WO2018177444A3 - 一种氮杂非那烯-3-酮的衍生物及其制备方法与应用 - Google Patents
一种氮杂非那烯-3-酮的衍生物及其制备方法与应用 Download PDFInfo
- Publication number
- WO2018177444A3 WO2018177444A3 PCT/CN2018/088201 CN2018088201W WO2018177444A3 WO 2018177444 A3 WO2018177444 A3 WO 2018177444A3 CN 2018088201 W CN2018088201 W CN 2018088201W WO 2018177444 A3 WO2018177444 A3 WO 2018177444A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- derivative
- azaphenalene
- preparation
- application
- method therefor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/497,773 US10669274B2 (en) | 2017-03-31 | 2018-05-24 | Azaphenalene-3-one derivative, preparation method therefor, and application therof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710205740.2A CN106883232B (zh) | 2017-03-31 | 2017-03-31 | 一种氮杂非那烯-3-酮的衍生物及其制备方法与应用 |
CN201710205740.2 | 2017-03-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2018177444A2 WO2018177444A2 (zh) | 2018-10-04 |
WO2018177444A3 true WO2018177444A3 (zh) | 2018-11-22 |
Family
ID=59182652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2018/088201 WO2018177444A2 (zh) | 2017-03-31 | 2018-05-24 | 一种氮杂非那烯-3-酮的衍生物及其制备方法与应用 |
Country Status (3)
Country | Link |
---|---|
US (1) | US10669274B2 (zh) |
CN (1) | CN106883232B (zh) |
WO (1) | WO2018177444A2 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106883232B (zh) * | 2017-03-31 | 2019-01-22 | 苏州康润医药有限公司 | 一种氮杂非那烯-3-酮的衍生物及其制备方法与应用 |
CN113527332B (zh) * | 2020-04-13 | 2022-07-26 | 南开大学 | 具有生物活性的卡波特韦衍生物及其制备方法和应用 |
CN112851558B (zh) * | 2021-02-05 | 2022-01-07 | 大连理工大学 | 2-氰基非那烯酮类化合物及其在白血病治疗中的应用 |
CN116253655A (zh) * | 2023-03-10 | 2023-06-13 | 宁夏顺邦达新材料有限公司 | 一种合成邻氨基苯甲酸甲酯的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102341394A (zh) * | 2009-01-23 | 2012-02-01 | 武田药品工业株式会社 | 聚(adp-核糖)聚合酶(parp)抑制剂 |
CN103703004A (zh) * | 2011-12-31 | 2014-04-02 | 百济神州有限公司 | 作为parp抑制剂的稠合的四环或五环的二氢二氮杂*并咔唑酮 |
CN106083849A (zh) * | 2011-12-31 | 2016-11-09 | 百济神州有限公司 | 作为parp抑制剂的稠合的四元或五元环吡啶并酞嗪酮类化合物 |
CN106883232A (zh) * | 2017-03-31 | 2017-06-23 | 苏州康润医药有限公司 | 一种氮杂非那烯‑3‑酮的衍生物及其制备方法与应用 |
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2017
- 2017-03-31 CN CN201710205740.2A patent/CN106883232B/zh active Active
-
2018
- 2018-05-24 WO PCT/CN2018/088201 patent/WO2018177444A2/zh active Application Filing
- 2018-05-24 US US16/497,773 patent/US10669274B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102341394A (zh) * | 2009-01-23 | 2012-02-01 | 武田药品工业株式会社 | 聚(adp-核糖)聚合酶(parp)抑制剂 |
CN103703004A (zh) * | 2011-12-31 | 2014-04-02 | 百济神州有限公司 | 作为parp抑制剂的稠合的四环或五环的二氢二氮杂*并咔唑酮 |
CN106083849A (zh) * | 2011-12-31 | 2016-11-09 | 百济神州有限公司 | 作为parp抑制剂的稠合的四元或五元环吡啶并酞嗪酮类化合物 |
CN106883232A (zh) * | 2017-03-31 | 2017-06-23 | 苏州康润医药有限公司 | 一种氮杂非那烯‑3‑酮的衍生物及其制备方法与应用 |
Also Published As
Publication number | Publication date |
---|---|
US10669274B2 (en) | 2020-06-02 |
US20200031828A1 (en) | 2020-01-30 |
WO2018177444A2 (zh) | 2018-10-04 |
CN106883232B (zh) | 2019-01-22 |
CN106883232A (zh) | 2017-06-23 |
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