WO2018157328A1 - Endoprothèse auto-expansible ouverte en spirale - Google Patents

Endoprothèse auto-expansible ouverte en spirale Download PDF

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Publication number
WO2018157328A1
WO2018157328A1 PCT/CN2017/075316 CN2017075316W WO2018157328A1 WO 2018157328 A1 WO2018157328 A1 WO 2018157328A1 CN 2017075316 W CN2017075316 W CN 2017075316W WO 2018157328 A1 WO2018157328 A1 WO 2018157328A1
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WO
WIPO (PCT)
Prior art keywords
winding
sawtooth waveform
section
connection
connecting bridge
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PCT/CN2017/075316
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English (en)
Chinese (zh)
Inventor
王成
王媛茹
张正亮
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浙江巴泰医疗科技有限公司
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Priority to PCT/CN2017/075316 priority Critical patent/WO2018157328A1/fr
Publication of WO2018157328A1 publication Critical patent/WO2018157328A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other

Definitions

  • the invention relates to the technical field of implantable medical instruments, in particular to a spiral open self-expanding stent.
  • the medical stent can be placed in the diseased blood vessel segment to support and smooth the blood vessel wall, and is often used for angioplasty to repair and reconstruct blood vessels. Placement of the stent within the damaged arterial segment prevents elastic retraction and arterial closure, as well as preventing localized incision of the artery along the intermediate layer.
  • the stent can be used in any human physiological lumen, such as the arteries, veins, bile ducts, urinary tract, digestive tract, tracheobronchial tree, brain water tube or the lumen of the genitourinary system, and of course can also be placed in the lumen of the animal.
  • stents in terms of deployment in a blood vessel: a self-expanding stent and a balloon-expandable stent.
  • the balloon-expandable stent inserts an unexpanded stent into the damaged area of the blood vessel.
  • the balloon is inflated by inflating the balloon by inflating the balloon, and the inflation process reshapes the atheroma.
  • the stent is fixed in the damaged blood vessel.
  • a problem with the balloon-expandable stent is that, as time passes, if the stent lacks expansion elasticity, the inner diameter of the stent gradually becomes smaller, and eventually collapses due to the natural elastic retraction of the blood vessel.
  • self-expanding stents are self-expanding and have many different designs including: spiral, circular, cylindrical, rolled, stepped, high-order coiled, braided or mesh.
  • the self-expanding stent is composed of a superelastic metal or a shape memory metal (see, for example, U.S. Patent No. 6,013,854 to Moriuchi), by inserting a stent in a compressed state into a damaged narrow blood vessel segment, once the compression force is removed, the stent self The lumen that swells and fills the blood vessels.
  • a tube having an outer diameter smaller than the inner diameter of the damaged blood vessel region can be used to compress the stent. When the stent is released from the restricted state in the tube, the stent expands to restore its original shape, thereby adhering to the vessel wall and firmly fixing the vessel in.
  • a stent formed in a simple cylindrical shape is not easily compressed, resulting in difficulty in inserting the stent into a damaged portion of the blood vessel safely.
  • One of the prior art stent designs that overcomes this problem is to provide a stent formed by a zigzag-shaped element, as described in U.S. Patent No. 5,562,697 to Christians.
  • the stent formed by the zigzag pattern has flexibility in the axial direction so that the stent can be transported and deformed as the vessel deforms.
  • this type of stent often lacks sufficient radial strength to maintain The openness of the blood vessels after elastic retraction.
  • the serrated elements can be coupled to the connecting elements.
  • U.S. Patent No. 6,042,597 to Kveen et al. discloses a balloon expansion stent formed by a continuous helical element having a wavy portion forming peaks and troughs, adjacent undulating portions All peaks are connected by curve elements Pick up. The connecting elements between adjacent undulating portions may impair the softness of the stent.
  • the other method is to provide a plurality of interconnected units, which are in the form of a diamond or a rhomboid, such as a stent design disclosed in U.S. Patent No. 6,063,113 to retet al.
  • the stent has a rigidly interlocking unit, so this type of stent has a relatively high stiffness and cannot be bent to accommodate changes in vessel shape.
  • the invention provides a geometric design for the bracket, which has good softness, sufficient radial strength and axial strength at the same time, and has good use effect, and can keep the blood vessel unblocked for a long time without failing.
  • the design also allows it to be inserted into complex small-diameter blood vessels that dynamically respond to changes in blood pressure.
  • the technical aim of the present invention is to provide a spiral open self-expanding stent, which has good flexibility, high flexibility, high radial strength and high axial strength, and has a good smoothing effect. , long-lasting effectiveness.
  • a spiral open self-expanding stent comprising a main body, a transition region connected to both end portions of the main body, and a distal end portion connected to the transition region, the main body including a spiral arrangement a first sawtooth waveform winding, the first sawtooth waveform windings being connected by a first connecting bridge; the end region comprising a second sawtooth waveform winding, the end region passing through the transition region a second connecting bridge is connected, the main body, the transition zone, and the end zone collectively enclosing a tubular structure, the self-expanding stent having a collapsed diameter for insertion into a blood vessel and for abutting in the blood vessel An expansion diameter, the transition region includes a third sawtooth waveform winding, a fourth sawtooth waveform winding, and a fifth sawtooth waveform winding, wherein the fourth sawtooth waveform winding and the fifth sawtooth waveform winding are both connected to
  • the first sawtooth waveform winding comprises a plurality of first winding units, the first winding unit comprising a first winding connection post and a first winding connected to a top end of the first winding connection post a wire connecting segment;
  • the second sawtooth waveform winding includes a plurality of second winding units, the second winding unit includes a second winding connecting post and is connected to the second winding connecting post a second winding connection segment of the top end;
  • the third sawtooth waveform winding includes a plurality of third winding units, the third winding unit includes a third winding connection post and is connected to the third winding connection a third winding connection segment at the top end of the column;
  • the fourth sawtooth waveform winding includes a plurality of fourth winding units, the fourth winding unit includes a fourth winding connection post and is connected to the fourth winding a fourth winding connection segment connecting the top ends of the columns;
  • the fifth sawtooth waveform winding includes a plurality of fifth winding units
  • the fifth winding connection section and the third sawtooth section of the first section of the fifth sawtooth connection section/the fourth sawtooth waveform winding of the fifth sawtooth waveform winding are connected, and the beginning of the fourth winding connection column/the fifth sawtooth waveform winding of the first section of the fourth sawtooth waveform winding
  • a top end of the fifth winding connection post and a third winding connection post of the third sawtooth waveform winding are connected by a sixth connecting bridge.
  • the fifth winding connection post and the third sawtooth of the first section of the fourth winding connection post/the fifth sawtooth waveform winding of the fourth sawtooth waveform winding There is a deformation transition space between the third winding connection columns of the last section of the waveform winding, and the span of the deformation transition space is defined by the sixth connection bridge.
  • one end of the sixth connecting bridge is connected to a central portion of the third winding connecting post of the last section of the third sawtooth waveform winding, and the length of the middle portion occupies the third sawtooth
  • the third winding of the last section of the waveform winding connects 1/3 of the length of the column.
  • the first connecting bridge, the third connecting bridge, the fourth connecting bridge, and the fifth connecting bridge are inclined to the same side with respect to the long axis of the bracket; the tilting direction of the sixth connecting bridge The direction of inclination of the first connecting bridge, the third connecting bridge, the fourth connecting bridge, and the fifth connecting bridge is the same.
  • the degree of inclination of the sixth connecting bridge is smaller than the inclination of the first connecting bridge, the third connecting bridge, the fourth connecting bridge, and the fifth connecting bridge.
  • the toughness of the sixth connecting bridge is stronger than the toughness of the first connecting bridge, the third connecting bridge, the fourth connecting bridge, and the fifth connecting bridge.
  • each of the first winding connection columns has the same length; the lengths of the third winding connection column, the fourth winding connection column, and the fifth winding connection column are respectively started by respective The section gradually increases toward the last section.
  • the length of the third connecting bridge is gradually increased and has the same increasing direction with respect to the third winding connecting post.
  • the length of the third winding connection column varies from 1.0 to 1.5 times the first winding connection column.
  • the length of the fourth winding connection column varies from 0.5 to 1.0 times the length of the first winding connection column.
  • the length of the fifth winding connection column varies from 0.5 to 1.0 times the length of the first winding connection column.
  • said first connecting bridge is connected between two said first winding connecting sections belonging to two sets of said first sawtooth waveform windings; said second connecting bridge being connected to said second winding Between the wire connecting segment and the third winding connecting segment, between the second winding connecting segment and the fifth winding connecting segment; the third connecting bridge is connected to the third winding connection Between the segment and the first winding connection segment; the fourth connection bridge is connected between the fourth winding connection segment and the first winding connection segment; the fifth connection bridge is connected to the Between the fourth winding connection segment and the fifth winding connection segment.
  • each of the first sawtooth waveform windings is connected to the first connecting bridge every second of the first winding connecting segments.
  • two third winding connecting sections and two first winding connecting sections are spaced apart between adjacent third connecting bridges.
  • two of the fourth winding connecting sections and two of the first winding connecting sections are spaced apart between adjacent fourth connecting bridges.
  • the radial strength is defective, and the support effect on the blood vessel is correspondingly weakened, and as the circumferential span gradually increases, the sawtooth
  • the longitudinal dimension of the wave winding must increase, the overall structural stability is poor, the strength effect is discounted, and it is difficult to control, further weakening the supporting force, and the effect in the patient is often unsatisfactory;
  • brackets that re-improve the transition zone, replacing the original single sawtooth waveform winding with a pair of sawtooth waveform windings connected to the bridge pillars, the bridge pillars increasing clockwise or counterclockwise relative to the long axis of the bracket Fitting the space in the transition zone, the bridge column can cooperate with the sawtooth waveform winding to form a closed frame.
  • the structure of the transition zone makes the overall spatial structure and support capacity have higher stability and structural strength, but the same transition
  • the invention further designs, on the basis of the conventional support structure, a transition zone composed of the third sawtooth waveform winding, the fourth sawtooth waveform winding, and the fifth sawtooth waveform winding, and has the following Significant technical effects:
  • the overall structural composition of the bracket is combined with good material selection and processing technology in actual production, the axial bending and stretching performance is good, and the radial supporting force is strong, so that the bracket has good flexibility and high diameter.
  • the direction and high axial strength can also be ensured, the structure is tight, and the expansion is uniform;
  • the structural design of the fourth sawtooth waveform winding and the fifth sawtooth waveform winding can make the spatial shape of the expanded shape more stable, further improving the radial supporting force and the axial stretching capability;
  • the structure of the fourth sawtooth waveform winding and the fifth sawtooth waveform winding and the structure of the third sawtooth waveform winding mutually assist each other to adjust respective circumferential span ranges, so that the two structures of the transition zone
  • the strength is kept at a good value, and its circumferential span can also be adjusted within the preferred effect value, while at the same time helping to increase the application amount of the drug coating, improving the anti-distraction effect, and exerting good and lasting performance.
  • connection structure between the fourth sawtooth waveform winding, the fifth sawtooth waveform winding and the third sawtooth waveform winding makes the expansion uniformity and flexibility of the transition zone effectively ensured, especially
  • the sixth connecting bridge and the deformation transition space can smoothly and effectively bear and conduct the force when the transition zone is expanded, so that the expansion movement of the entire transition zone is consistent, and the sixth connecting bridge and the The deformation transition space is disposed at a position where the third sawtooth waveform winding is connected to the fourth sawtooth waveform winding and the fifth sawtooth waveform winding, and the force of the foregoing two structures can be applied.
  • the technical advantage of the present invention is that the spiral open self-expanding stent has a reasonable structure and convenient use, and the whole stent has good flexibility, high axial strength and high radial strength, and can have sufficient axial force in the blood vessel and
  • the radial force causes the stent to expand in a timely, complete and uniform manner, and the support for the vessel wall is uniform and stable.
  • the force at both ends is uniform and the shape is good, and the adaptability to the application in different blood vessels is better, and It has a good and long-lasting smoothness during use, which greatly improves the use effect and prolongs the service life.
  • FIG. 1 is a schematic structural view of an embodiment of the present invention
  • FIG. 2 is a schematic partial structural view of an embodiment of the present invention.
  • FIG. 3 is a schematic structural view of an outer flaring according to an embodiment of the present invention.
  • the names of the parts corresponding to the numbers in the figure are: 1-body, 11-first winding connection column, 12-first winding connection section, 2-transition zone, 21-third winding connection column, 22- Three winding connection section, 3-terminal zone, 31-second winding connection column, 32-second winding connection section, 4-first connection bridge, 23-fourth winding connection column, 24-fourth winding Wire connection section, 25-fifth winding connection post, 26-fifth winding connection section, 5-second connection bridge, 6-third connection bridge, 7-fourth connection bridge, 8-fifth connection bridge, 9- sixth bridge.
  • a spiral open self-expanding stent comprises a body 1, a transition zone 2 connected to both ends of the body 1, and a terminal zone 3 connected to the transition zone 2, the body 1 comprising a spiral arrangement
  • the first sawtooth waveform is wound, the first sawtooth waveform winding is connected by the first connecting bridge 4; the end region 3 includes a second sawtooth waveform winding, and the end region 3 and the transition region 2 are passed through the second connecting bridge 5
  • the main body 1, the transition zone 2, and the end zone 3 together form a tubular structure
  • the self-expanding stent has a collapsed diameter for insertion into the blood vessel and an expanded diameter for abutting in the blood vessel, and the entire end zone 3 is formed.
  • the well-called closed-loop structure is beneficial to the uniform force of the two ends of the bracket during the pushing and releasing process, the uniformity of the stent when expanding, and the overall structural strength of the bracket is strengthened at the same time.
  • the second sawtooth waveform winding can also be set to 2 groups or more, and the second sawtooth waveform windings can be interconnected by re-setting the connecting bridge, generally in the same manner as the second connecting bridge 5. It can also be seen in FIG.
  • the second sawtooth waveform winding forms an outer flare relative to the long axis of the stent when the stent is in the expanded state
  • the external expansion angle ⁇ of the outer flare relative to the longitudinal axis of the stent is preferably 10 Degree, can stably and firmly adhere to the inner wall of the blood vessel, avoiding the deviation of the stent in the blood vessel.
  • the length of the second winding connection post 31 is greater than the length of the first winding connection post 11, and the thickness or the maximum radial span of the actual second winding connection post 31 is the same as that of the first winding connection post 11 to ensure the overall structure.
  • the design is consistent and has a superior effect.
  • the design is advantageous for the crimping of the bracket. If the second bobbin connecting rod 31 is short, it is easy to be lifted when the bracket is pressed, and the crimping is very difficult.
  • the end region 3 further includes a developing body disposed on the second winding connecting portion 32.
  • the developing body is an X-ray opaque marker such as enamel or platinum or gold, which can play a large role in guiding and positioning the stent in the blood vessel. Generally, five developing bodies are arranged in each end zone 3, which increases the stress point of the stent when released, which is favorable for the conduction of the release force.
  • the transition zone 2 includes a third sawtooth waveform winding, a fourth sawtooth waveform winding, and a fifth sawtooth waveform winding, and the fourth sawtooth wave
  • the shape winding and the fifth sawtooth waveform winding are both connected to the third sawtooth waveform winding; the third sawtooth waveform winding and the first sawtooth waveform winding are connected by the third connecting bridge 6, and the fourth sawtooth waveform winding
  • the fourth connecting bridge 7 is connected with the first sawtooth waveform winding, and the fourth sawtooth waveform winding and the fifth sawtooth waveform winding are connected by the fifth connecting bridge 8.
  • the first sawtooth waveform winding includes a plurality of first winding units, the first winding unit includes a first winding connection post 11 and a first winding connection section 12 connected to a top end of the first winding connection post 11;
  • the sawtooth waveform winding includes a plurality of second winding units, the second winding unit includes a second winding connection post 31 and a second winding connection section 32 connected to the top end of the second winding connection post 31;
  • the third sawtooth waveform The winding includes a plurality of third winding units, the third winding unit includes a third winding connection post 21 and a third winding connection section 22 connected to the top end of the third winding connection post 21;
  • the fourth sawtooth waveform winding A plurality of fourth winding units including a fourth winding connection post 23 and a fourth winding connection section 24 connected to the top end of the fourth winding connection post 23;
  • the fifth sawtooth waveform winding includes a plurality of A fifth winding unit, the fifth winding
  • the wire connecting segments 22 are connected, the first zigzag connecting string 23 of the fourth sawtooth waveform winding, the first one of the fifth winding connecting post 25, and the third sawtooth waveform of the fifth winding connecting post 25
  • the last section of the winding, the third winding connection post 21 is connected by the sixth connecting bridge 9, and the "/" separator in the foregoing means two optional setting positions, such as the setting position of the sixth connecting bridge 9. Can be on the opposite left or right side of the figure.
  • the first section of the fourth sawtooth waveform winding, the fourth winding connection post 23 / the fifth sawtooth waveform winding, the first section, the fifth winding connection post 25 and the third sawtooth waveform winding, the last section of the third winding There is a deformation transition space between the line connecting columns 21, and the span of the deformation transition space is defined by the sixth connecting bridge 9.
  • One end of the sixth connecting bridge 9 is connected to the central portion of the last third winding connecting post 21 of the third sawtooth waveform winding, and the length of the middle portion occupies the last third winding of the third sawtooth waveform winding.
  • the wire connects the column 21 to 1/3 of the length.
  • the connection position of the sixth connecting bridge 9 can conform to the action when the transition zone is released from expansion, and ensures that the deformation transition space has a suitable effective spatial position as well as a lateral span and a longitudinal span.
  • the first connecting bridge 4, the third connecting bridge 6, the fourth connecting bridge 7, and the fifth connecting bridge 8 are inclined to the same side with respect to the long axis of the bracket; the inclined direction of the sixth connecting bridge 9 and the first connecting bridge 4, The inclination directions of the third connecting bridge 6, the fourth connecting bridge 7, and the fifth connecting bridge 8 are the same, and the inclination of the sixth connecting bridge 9 is smaller than that of the first connecting bridge 4, the third connecting bridge 6, and the fourth connecting bridge 7, The degree of inclination of the fifth connecting bridge 8 ensures that the sixth connecting bridge 9 can cooperate with the deformation transition space to make the release stress of the transition zone smoothly and uniformly, and ensure the flexibility and consistency of the overall support, and at the same time, the deformation transition space can be
  • the span in the direction of the short axis of the stent is limited to a suitable value.
  • the toughness of the sixth connecting bridge 9 is stronger than the toughness of the first connecting bridge 4, the third connecting bridge 6, the fourth connecting bridge 7, and the fifth connecting bridge 8.
  • the sixth connecting bridge 9 is a key point of action of the force transition, and has better adaptability to different application environments and is not easy to break.
  • the second connecting bridge 5 is parallel with respect to the long axis of the bracket, ie In practice, the two ends of the second connecting bridge 5, that is, the second winding connecting section 32 and the third winding connecting section 22, and the second winding connecting section 32 and the fifth winding connecting section 26 are all facing each other.
  • the second sawtooth waveform winding is also a circumferentially flush section rather than a spiral arrangement, which can make the whole stent have good expansion uniformity, and there are such two sections with uniform force and strong structural strength at both ends.
  • the segment also maintains a tubular support in appearance.
  • the length of each of the first winding connection columns 11 is equal; the lengths of the third winding connection column 21, the fourth winding connection column 23, and the fifth winding connection column 25 are all from the first section to the last section. Gradually increase.
  • the length of the third connecting bridge 6 gradually increases and has the same increasing direction with respect to the third winding connecting post 21.
  • the third connecting bridge 6 cooperates with the structure of the sixth connecting bridge 9 and the deformation transition space to have different lengths here to ensure the flexibility and consistency of the overall expansion of the bracket.
  • the length of the third winding connection post 21 varies from 1.0 to 1.5 times the first winding connection post 11
  • the length of the fourth winding connection post 23 varies from 0.5 to 1.0 times the first winding connection post 11 .
  • the length of the fifth winding connection post 25 varies from 0.5 to 1.0 times of the first winding connection column 11, and the support is unstable. If the size is too small, the flexibility, expansion or shrinkage may be reduced, and the actual third winding is practical.
  • the thickness or the maximum radial span of the connecting post 21, the fourth winding connecting post 23, and the fifth winding connecting post 25 are the same as those of the first winding connecting post 11, ensuring overall structural consistency and superior effects.
  • the first connecting bridge 4 is connected between two first winding connecting segments 12 belonging to two adjacent first sawtooth waveform windings; the second connecting bridge 5 is connected to the second winding connecting portion 32 and the third winding Between the line connecting sections 22, between the second winding connecting section 32 and the fifth winding connecting section 26; the third connecting bridge 6 is connected between the third winding connecting section 22 and the first winding connecting section 12; The fourth connecting bridge 7 is connected between the fourth winding connecting section 24 and the first winding connecting section 12; the fifth connecting bridge 8 is connected between the fourth winding connecting section 24 and the fifth winding connecting section 26.
  • a first connecting bridge 4 is connected to every two first winding connecting segments 12 of each set of first sawtooth waveform windings.
  • the first connecting bridge 4 is wound by two adjacent first sawtooth waveforms.
  • the number of installations is 5-6, and the two first winding connection segments 12 connected are not facing each other, but are staggered from each other; there are two second spaces between adjacent two second connecting bridges 5 Winding connection section 32 and two third winding connection sections 22 or two fifth winding connection sections 26 or a third winding connection section 22 and a fifth winding connection section 26, generally said second connection
  • the number of the bridges 5 is 5-6, and the connected second winding connecting section 32 and the third winding connecting section 22 or the second winding connecting section 32 and the fifth winding connecting section 26 are mutually positive.
  • the second connecting bridge 5 is parallel with respect to the long axis of the bracket; between the adjacent third connecting bridges 6, there are two third winding connecting sections 22 and two first winding connecting sections 12, generally The number of the third connecting bridges 6 is 2-3, and the connected first winding connecting section 12 and the third winding connecting section 22 are not directly opposite, but Between the adjacent fourth connecting bridges 7, there are two fourth winding connecting segments 24 and two first winding connecting segments 12, generally the number of the third connecting bridges 6 is 2 to 3
  • the first winding connecting section 12 and the fourth winding connecting section 24 are not aligned, but are mutually offset; the number of the fifth connecting bridges 8 can be set as needed, because the fifth connecting bridge 8 can be matched
  • the fourth sawtooth waveform winding and the fifth sawtooth waveform winding form a plurality of
  • the edge-shaped closed frame can be determined by the requirements of drug coating, cost input, and structural strength required by the polygonal closed frame.
  • the fourth winding connection segment 24 and fifth are connected.
  • the winding connecting sections 26 are also not facing each other, but are staggered from each other; of course, the size of the brackets has common and special specifications, and the above-mentioned number setting is also changed correspondingly with the size of the brackets. These settings facilitate the carriage being pushed. And the conduction of force during release, the stent can release enough axial force to release the stent in the blood vessel in a timely and complete manner, avoiding delayed release or incomplete release, and enhancing axial bending performance.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

La présente invention concerne une endoprothèse auto-expansible ouverte en spirale, comprenant un corps (1), des régions de transition (2) reliées aux deux extrémités du corps (1), et des régions d'extrémité arrière (3) reliées aux régions de transition (2). Le corps (1) comprend des premiers enroulements en forme d'onde en dents de scie qui sont disposés en spirale. Les premiers enroulements en forme d'onde en dents de scie sont reliés au moyen d'un premier pont de connexion (4). Chaque région d'extrémité arrière (3) comprend des seconds enroulements en forme d'onde en dents de scie. La région d'extrémité arrière (3) et la région de transition (2) sont reliées au moyen d'un second pont de connexion (5). Le corps (1), les régions de transition (2) et les régions d'extrémité arrière (3) entourent ensemble une structure tubulaire. L'endoprothèse auto-extensible a un diamètre réduit pour une mise en place dans un vaisseau sanguin et un diamètre d'expansion pour un déploiement dans le vaisseau sanguin. L'endoprothèse auto-extensible présente une structure raisonnable et est pratique à utiliser, et présente une flexibilité élevée, une résistance radiale et axiale élevée, et un bon effet de service durable.
PCT/CN2017/075316 2017-03-01 2017-03-01 Endoprothèse auto-expansible ouverte en spirale WO2018157328A1 (fr)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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