WO2018155974A1 - Composition cosmétique pour filtrer la lumière bleue et bloquer les rayons ultraviolets - Google Patents

Composition cosmétique pour filtrer la lumière bleue et bloquer les rayons ultraviolets Download PDF

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Publication number
WO2018155974A1
WO2018155974A1 PCT/KR2018/002319 KR2018002319W WO2018155974A1 WO 2018155974 A1 WO2018155974 A1 WO 2018155974A1 KR 2018002319 W KR2018002319 W KR 2018002319W WO 2018155974 A1 WO2018155974 A1 WO 2018155974A1
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WIPO (PCT)
Prior art keywords
cosmetic composition
visible light
blocking
hydrophobic
less
Prior art date
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PCT/KR2018/002319
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English (en)
Korean (ko)
Inventor
박정은
윤혜인
김형준
김선영
Original Assignee
(주)아모레퍼시픽
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by (주)아모레퍼시픽 filed Critical (주)아모레퍼시픽
Priority to CN201880023294.6A priority Critical patent/CN110494115B/zh
Priority to SG11201907890UA priority patent/SG11201907890UA/en
Publication of WO2018155974A1 publication Critical patent/WO2018155974A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29—Titanium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds

Definitions

  • OIL-DISPERSIBILITY refers to a property or degree that is well dispersed in an oil or oil component, and is a concept included in hydrophobicity.
  • WATER-DISPERSIBILITY refers to a property or degree that is well dispersed in water or a water-soluble substance, and is a concept included in hydrophilicity.
  • coloring component refers to pigments, pigments, and other materials having the ability to produce color. It may include a “pigment”, preferably a pigment component that can be used as a raw material for cosmetics.
  • Coloring components are titanium dioxide, micro titanium oxide (Micro TiO 2 ), zinc oxide, zinc oxide, micro zinc oxide (Micro ZnO), iron oxide (iron oxide, FeO (II), Fe 2 O 3 ( III), Fe 3 O 4 (IV)), aluminum oxide (alumina, Al 2 O 3 ), barium sulfate (barium sulfate, BaSO 3 ), PMMA (polymethylmethacrylate), silica, nylon, polyurethane, ultra It may be one or more selected from the group consisting of marine, pearl, synthetic mica, mica, talc, kaolin, sericite and boron nitride, but is not limited thereto.
  • anionic surfactant means that the portion of the surfactant that is ionized when dissolved in water becomes anion.
  • Surfactants include nonionic surfactants (surfactants that do not dissociate into aqueous solutions because they do not have an ionizing atomic group in their molecules), and cationic surfactants (surfactants that become valence cations that dissolve in water and dissociate into ions). ), Anionic surfactants, and amphoteric surfactants (surfactants having both a cationic group and an anionic group in the same molecule).
  • phosphate surfactant refers to a surfactant comprising a chemical structural phosphate
  • glutamate surfactant refers to a surfactant comprising a chemical structural glutamate
  • carbamate surfactant refers to a chemical structural carbamate Means a surfactant containing.
  • the oil phase including a sunscreen and silicone oil;
  • An aqueous phase including at least one thickener selected from the group consisting of phosphate surfactants, glutamate surfactants and carbamate surfactants;
  • a hydrophobic visible light blocking agent homogeneously dispersed for example, in the form of emulsion particles
  • the particle size of the dispersed emulsion may have an average diameter of 0.1 to 20 ⁇ m as measured by an optical microscope.
  • the average diameter is 0.1 ⁇ m, 0.5 ⁇ m, 0.8 ⁇ m, 1 ⁇ m, 1.2 ⁇ m, 1.5 ⁇ m, 2 ⁇ m, 3 ⁇ m, 4 ⁇ m, 5 ⁇ m, 7 or at least 9 ⁇ m, at least 9 ⁇ m, at least 12 ⁇ m, at least 15 ⁇ m, or at least 18 ⁇ m.
  • the average diameter may be 20 ⁇ m or less, 18 ⁇ m or less, 15 ⁇ m or less, 13 ⁇ m or less, 10 ⁇ m or less, 8 ⁇ m or less, 6 ⁇ m or less, 4 ⁇ m or less, 2 ⁇ m or less, 1 ⁇ m or less, 0.8 ⁇ m or less, 0.5 ⁇ m or less, or 0.2 ⁇ m or less.
  • the average diameter may be 1 to 5 ⁇ m.
  • the sunscreen may be at least one of an organic sunscreen and an inorganic sunscreen.
  • the silicone oil may be at least one selected from the group consisting of silicone oils including cyclomethicone, dimethicone, cyclopentasiloxane, and cyclohexasiloxane.
  • the silicone oil may be at least one of cyclopentasiloxane and cyclohexasiloxane.
  • the hydrocarbon-based oil including squalane or mineral oil in place of the silicone oil; Ester-based oils including isopropyl palmitate, 2-octyldodecyl myristate, isopropyl mysteryte or butyloctyl salicylate; And vegetable oils, including castor oil, olive oil or jojoba oil.
  • Surfactants that can be used in the composition according to an aspect of the present invention include anionic surfactants such as sulfates, sulfosuccinates, sacosinates, phosphates, isethionates, glutamate, taurates, and the like.
  • the hydrophilic group may have a phosphate, sulfate, glutamate or citrate, etc., and the counterion may have sodium, potassium or ammonium, and the hydrophobic group generally has a fatty alkyl group between C2 and C24 Surfactants can be used.
  • the surfactant may be a phosphate surfactant or glutamate surfactant, and instead of the anionic surfactant, a carbamate surfactant (surfactant comprising carbamate in chemical structure, preferably inulin lauryl carbamate) May be used.
  • a carbamate surfactant surfactant comprising carbamate in chemical structure, preferably inulin lauryl carbamate
  • potassium cetylphosphate, aluminum isostearyl glyceryl phosphate, sodium lauryl sulfate, sodium stearoyl glutamate, and inulin lauryl carbamate It may be one or more, more preferably potassium cetylphosphate.
  • the cosmetic composition according to one aspect of the present invention may further contain one or more emulsifiers in addition to the above components.
  • emulsifiers for example, Lecithin, Hydrogenated Lecithin, Lysolecithin, Hydrogenated Dryosolecithin, Polysorbate 60, Fiji-40 Stearate, Octyldodeces-25, Ceteares-20, Fiji-20 Glycerin
  • It may further contain one or more emulsifiers selected from the group consisting of rilisisostearate, polyglyceryl-3 methylglucose distearate, cetearylglucoside, polyglyceryl-10 stearate, and the like, but is not limited thereto. It is not.
  • the emulsifier further contained may contain 0.01 to 10 wt% based on the total weight of the cosmetic composition. If it is less than 0.01% by weight it is difficult to achieve the emulsification purpose, if it exceeds 10% by weight it may irritate the skin.
  • any one or more phases of the water phase and oil phase may further comprise a thickener.
  • a thickener for example, sodium acrylate copolymers, crosslinked or uncrosslinked acrylic acid polymers, in particular polyacrylic acids, cellulose derivatives crosslinked with polyfunctional functional groups (such as methylcellulose, hydroxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl methylcellulose, carboxy Methyl cellulose, carboxymethyl cellulose), sodium salt of cellulose derivative, cetylstearyl alcohol, oxyethylenated cetylstearyl alcohol containing ethylene oxide, guar gum, xanthan gum and combinations thereof. have.
  • the thickener may be contained in 0.001 to 20.0% by weight in the total composition.
  • the hydrophobic visible light blocker may be an inorganic powder surface-treated hydrophobic.
  • the surface treatment is dimethicone, methicone, caprylyl silane with substituents introduced, lauroyl lysine, disodium stearoyl glutamate, sodium myristyl glutamate, silica, alumina, And it may be treated with one or more selected from the group consisting of aluminum hydroxide.
  • the harmful light blocking effect can be obtained and the skin tone correction effect can be achieved.
  • the hydrophobic visible light blocker or the hydrophobic surface-treated inorganic powder may be titanium dioxide coated with aluminum hydroxide and triethoxycaprylylsilane.
  • the content of the hydrophobic visible light blocker may be 0.5 to 5% by weight based on the total weight of the composition. If it is less than 0.5% by weight, the coloring or visible light blocking effect is weak, and if it exceeds 5% by weight, the dispersion in the formulation is not smooth, and the formulation stability is significantly lowered.
  • the content of the hydrophobic visible light blocker is 0.5% by weight, 0.8% by weight, 1% by weight, 1.2% by weight, 1.4% by weight, 1.6% by weight, 1.8% by weight, 2% by weight, 2.2% by weight Or at least 2.4 wt%, at least 2.6 wt%, at least 2.8 wt%, at least 3 wt%, at least 3.5 wt%, at least 4 wt%, at least 4.5 wt%, or at least 4.8 wt%.
  • the content is 5 wt% or less, 4.8 wt% or less, 4.5 wt% or less, 4 wt% or less, 3.5 wt% or less, 3 wt% or less, 2.8 wt% or less, 2.6 wt% or less, 2.4 wt% or less, It may be 2.2 wt% or less, 2 wt% or less, 1.8 wt% or less, 1.6 wt% or less, 1.4 wt% or less, 1.2 wt% or less, 1 wt% or less, 0.8 wt% or less, or 0.6 wt% or less. Preferably at least 1% by weight may be less than 3% by weight.
  • the content of the anionic surfactant is 2 wt% or less, 1.8 wt% or less, 1.6 wt% or less, 1.5 wt% or less, 1.4 wt% or less, 1.2 wt% or less, 1.0 wt% or less, 0.8 wt% or less, and 0.6 wt% or less. It may be up to weight percent, or up to 0.55 weight percent.
  • the visible light may have a wavelength of 380 ⁇ 800 nm.
  • the light source may be at least one of violet light having a wavelength of 380 to 430 nm, and blue light having a wavelength of 430 to 500 nm.
  • the cosmetic composition may be to block 60% or more of violet light.
  • the cosmetic composition comprises at least 60%, at least 65%, at least 68%, at least 70%, at least 75%, at least 78%, at least 80%, at least 85%, at least 90%, at least 95%, or 97% of violet light. It may be an abnormal blocking.
  • the composition may contain up to 98%, up to 95%, up to 90%, up to 85%, up to 80%, up to 78%, up to 75%, up to 70%, up to 68%, up to 65%, or up to 63% of the violet light. It may be to block below.
  • the cosmetic composition may be to block 35% or more blue light.
  • the composition comprises at least 35%, at least 36%, at least 38%, at least 40%, at least 42%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, or at least 68% of the blue light. It may be blocking.
  • the composition may contain 70% or less, 68% or less, 65% or less, 60% or less, 55% or less, 50% or less, 45% or less, 42% or less, 40% or less, 38% or less, or 36% blue light. It may be blocking below%.
  • the cosmetic composition may be an emulsion or a cream formulation.
  • the cosmetic composition may be an oil-in-water (O / W) emulsion formulation.
  • O / W oil-in-water
  • the present specification may be applied to other formulations, but may particularly relate to an O / W emulsion composition and a formulation stabilization method thereof.
  • O / W emulsions it is very difficult to disperse the hydrophobic visible light blocking agent (for example, titanium dioxide surface-treated with hydrophobic material, zinc oxide surface-treated with hydrophobic material, etc.), and even if dispersed, O / W formulation stability Although very difficult to maintain, the present invention solves such a challenge in one aspect.
  • the cosmetic composition may be a liquid or cream formulation.
  • the cosmetic composition may be that the stability of the formulation is maintained for more than 4 weeks at -30 °C to 60 °C.
  • the temperature is -30 ° C or more, -20 ° C or more, -10 ° C or more, -5 ° C or more, 0 ° C or more, 5 ° C or more, 10 ° C or more, 15 ° C or more, 20 ° C or more, 25 ° C
  • the said temperature is 60 degrees C or less, 55 degrees C or less, 50 degrees C or less, 45 degrees C or less, 40 degrees C or less, 35 degrees C or less, 30 degrees C or less, 25 degrees C or less, 20 degrees C or less, 15 degrees C or less, 10 degrees C or less, 5 Or less, or less than or equal to 0 ° C, or less than or equal to -5 ° C, or less than or equal to -10 ° C, or less than or equal to -20 ° C, or less than or equal to -25 ° C.
  • it may be -20 °C to 45 °C.
  • the stability may be maintained at -30 °C to 60 °C 4 weeks, at least 5 weeks, at least 6 weeks, at least 7 weeks, at least 8 weeks, or at least 9 weeks. Further, 10 weeks or less, 9 weeks or less, 8 weeks or less, 7 weeks or less, 6 weeks or less, or 5 weeks or less may be maintained.
  • the hydrophobic visible light blocker may be dispersed by homogenizing for 1 to 20 minutes at 5000 to 15000rpm. Preferably, it may be dispersed by homogenizing for 3 to 8 minutes at 8000 to 12000 rpm. In one embodiment, the homogenization may be to homogenize in the water phase, or in the oil phase.
  • the cosmetic composition may be obtained by homogeneously dispersing the hydrophobic visible light blocker and then emulsifying it with other raw materials or components. In one embodiment, the emulsification may be performed for 1 to 20 minutes at 5000 to 15000 rpm, and preferably for 3 to 6 minutes at 8000 to 12000 rpm.
  • the cosmetic composition may be for improving skin tone while simultaneously blocking visible light.
  • a hydrophobic visible light blocker eg, titanium dioxide surface-treated with a hydrophobic material
  • harmful visible light eg, one or more of blue light and violet light
  • the cosmetic composition may further include a functional additive and components included in the general cosmetic composition.
  • the functional additive may include, for example, a component selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymer peptides, polymer polysaccharides, sphingolipids, and seaweed extracts.
  • oils and fats moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, fungicides, antioxidants, plant extracts, pH adjusters, alcohols, pigments, flavorings, blood circulation And accelerators, cooling agents, limiting agents, purified water, and the like.
  • the cosmetic composition is not particularly limited in shape, and may be appropriately selected depending on the intended purpose.
  • face wash, cleaning product, exfoliating product, skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nourishing lotion, massage cream, nourishing cream, moisturizing cream, hand cream, foundation , Essence, nutrition essence, pack, soap, cleansing foam, cleansing gel, cleansing lotion, cleansing cream, body lotion and body cleanser may be prepared in any one or more forms selected from, but is not limited thereto. Preferably in the form of lotions or creams.
  • the carrier component is animal fiber, vegetable fiber, wax, paraffin, starch, trakant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide. And the like can be used.
  • a solvent, solvating agent or emulsifying agent is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, Fatty acid esters of propylene glycol, 1,3-butylglycol oil, glycerol aliphatic esters, polyethylene glycols or sorbitan.
  • an aliphatic alcohol sulfate an aliphatic alcohol ether sulfate, a sulfosuccinic acid monoester, isethionate, an imidazolinium derivative, methyl taurate, and sarcosinate
  • Fatty acid amide ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, linolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.
  • the present invention includes an oil phase including the sunscreen and silicone oil, at least one or more of the surfactants, and an aqueous phase including a thickener and a hydrophobic visible light blocker homogeneously dispersed in the aqueous phase. It may be to a method for blocking the visible light comprising the step of administering a cosmetic composition to the subject in need thereof.
  • the present invention includes an oil phase including the sunscreen and silicone oil, at least one or more of the surfactants, and an aqueous phase including a thickener and a hydrophobic visible light blocker homogeneously dispersed in the aqueous phase. It may be directed to a method for improving visible light blocking and skin tone, comprising administering a cosmetic composition to a subject in need thereof.
  • the present invention provides an oil phase part including the sunscreen agent and silicone oil, an aqueous phase part including at least one of the surfactant and a thickener, and an aqueous phase part, for preparing a cosmetic composition for blocking visible light. It may be directed to the use of a composition comprising a homogeneously dispersed hydrophobic light blocker.
  • the present invention provides an oil-based part including the sunscreen agent and silicone oil, an aqueous phase including at least one of the surfactants, and a thickener for producing a cosmetic composition for blocking visible light and improving skin tone. It may be related to the use of the composition comprising a hydrophobic visible light blocker homogeneously dispersed in the water phase.
  • the present invention provides an oil phase part including the sunscreen agent and silicone oil, at least one or more of the surfactants, and an aqueous phase part and the water phase part, for use in blocking visible light or improving skin tone. It may be directed to the use of a composition comprising a homogeneously dispersed hydrophobic light blocker.
  • the present invention is directed to the use of a surfactant contained in a specific content as one or more selected from the group consisting of a phosphate surfactant, a glutamate surfactant, and a carbamate surfactant to enhance formulation stability of the cosmetic composition. It may be about.
  • a cosmetic composition was prepared by dispersing TiO 2 for hydrophobic pigments (for coloring agents) in an aqueous phase of an O / W emulsion formulation using potassium cetylphosphate.
  • O / W emulsion formulations are prepared using the ingredients in Table 1 below, but may be prepared using conventional methods for preparing O / W emulsion formulations.
  • a sunscreen cosmetic composition comprising the ingredients listed in Table 1
  • the components of the oil phase in the table was mixed according to the numerical value (% by weight) in the table and warmed to 75 (mixture 1).
  • the aqueous phase components in the table were mixed according to the numerical values (% by weight) in the table and then warmed to 75 (mixture 2).
  • composition was prepared according to the above method, but the content (% by weight) for the specific component was changed according to Table 1 below.
  • composition according to the embodiment was measured whether the actual cosmetic composition and cosmetic preparation, formulation stability, UV blocking ability, harmful visible light (blue and violet) blocking effect, and investigated the presence of skin tone correction.
  • Formulation stability is determined by using the above-described embodiment after the actual cosmetic composition (e.g., sunscreen product) at -20 degrees, 5 degrees, room temperature, 30 degrees, 45 degrees for 4 weeks, whether the powder agglomeration, appearance changes It confirmed as a result of observing whether or not.
  • the actual cosmetic composition e.g., sunscreen product
  • the UVB protection factor (SPF) was measured according to the UV protection effect measurement method and standard by the ISO test method (ISO 24444).
  • 12 subjects suitable for the purpose of testing through medical history examination and skin condition diagnosis were irradiated with ultraviolet light using Multiport Solar UV Simulator (601-300W) on the unbacked area and after 16 ⁇ 24 hours Minimal Erythema Dose (MED) was determined.
  • Samples of the cosmetic composition shown in Table 1 above were uniformly applied to the skin at a thickness of 2 mg / cm 2 , respectively. Based on the uncoated MED, ultraviolet light was irradiated to determine the MED and SPF of the standard and test composition samples.
  • the UV blocking index (SPFi) for each subject was calculated and the UV blocking index of the composition sample was determined by an arithmetic mean value.
  • UV protection index (SPFi) for each subject minimum amount of erythema at the product application site / minimum amount of erythema at the product-free area
  • UVA protection dimension Protection Factor of UVA, PFA
  • PFA Photo-Protection Factor of UVA
  • the MPPD means the minimum sustained instant blackening amount (the minimum ultraviolet irradiation amount in which faint blackening is recognized) (“MPPD”).
  • the formulations of Examples and Comparative Examples were applied in an amount of 2 mg / cm 2 on quartz or a band pass filter, respectively, and then blue light / violet
  • the light source including the region was irradiated and the transmitted blue / violet light wavelength region (380-500 nm) was measured with an SPR-4001 spectroradiometer (Spectroradiometer, Luzchem, Canada).
  • compositions except for Example 3 can be prepared with regard to whether they can be made into sunscreen cosmetics (eg sunscreen products) in cream formulations.
  • sunscreen cosmetics eg sunscreen products
  • the hydrophobic visible light blocker was stable in an effective and homogeneously dispersed state in the water phase. Emulsion formulation is maintained). It does not contain the potassium cetyl phosphate, a water-dispersible coloring TiO 2 for In the case of Example 2 containing TiO 2 coated with a hydrophilic (water dispersible) material appeared to aggregate, it was impossible to maintain the formulation.
  • Example 3 which contained but did not contain potassium cetylphosphate, the hydrophobic visible light blocker (TiO 2 coated with a hydrophobic material) was not homogeneously dispersed in the water phase, so that emulsion stability was not maintained.
  • Formulation stability, UV blocking effect and harmful visible light blocking effect according to the content of potassium cetylphosphate were measured.
  • Experimental results of Experimental Examples 1 and 2 are considered to be similar when the composition is prepared using zinc oxide or iron oxide instead of titanium dioxide, and sodium stearoyl glutamate or inulin lauryl carbamate may be used instead of potassium cetylphosphate. It was confirmed that the case came out similarly.

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Abstract

La présente invention concerne une composition cosmétique huile dans l'eau pour filtrer la lumière bleue et bloquer un rayon ultraviolet, dans laquelle un agent de blocage de rayonnement visible hydrophobe est dispersé de manière uniforme dans une phase aqueuse, et une méthode pour maintenir la stabilité de la composition. En conséquence, le souhait de nombreux consommateurs très intéressés par ce domaine peut être atteint, et le développement d'industries pertinentes peut être favorisé.
PCT/KR2018/002319 2017-02-27 2018-02-26 Composition cosmétique pour filtrer la lumière bleue et bloquer les rayons ultraviolets WO2018155974A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201880023294.6A CN110494115B (zh) 2017-02-27 2018-02-26 用于过滤蓝光与阻隔紫外光的化妆品组合物
SG11201907890UA SG11201907890UA (en) 2017-02-27 2018-02-26 Cosmetic composition for filtering blue light and blocking ultraviolet ray

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Application Number Priority Date Filing Date Title
KR10-2017-0025307 2017-02-27
KR1020170025307A KR102672901B1 (ko) 2017-02-27 2017-02-27 유해 광선 차단 화장료 조성물

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WO2018155974A1 true WO2018155974A1 (fr) 2018-08-30

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KR102214051B1 (ko) * 2018-10-29 2021-02-09 코스맥스 주식회사 블루라이트 차단용 무기 입자를 포함하는 화장료 조성물
KR102168166B1 (ko) * 2018-11-08 2020-10-21 주식회사 코리아나화장품 블루라이트 차단용 화장료 조성물
WO2020149430A1 (fr) * 2019-01-16 2020-07-23 코스맥스 주식회사 Composition cosmétique bloquant les uv de type huile-dans-eau présentant une résistance à l'eau
KR102268228B1 (ko) * 2019-05-20 2021-06-24 코스맥스 주식회사 자외선 차단용 화장료 조성물
KR102298142B1 (ko) * 2019-10-29 2021-09-06 코스맥스 주식회사 티타늄디옥사이드가 이중 분산된 수중유형 자외선 차단용 화장료 조성물
CN113116736A (zh) * 2019-12-31 2021-07-16 新生活化妆品科技(上海)有限公司 一种无机复合粉体及制备方法、应用与化妆材料组合物
KR102362336B1 (ko) * 2020-06-01 2022-02-14 주식회사 초이스엔텍 자외선, 근적외선 및 블루라이트 차단용 징크옥사이드 유분산액 및 이를 포함하는 화장료 조성물
KR102176704B1 (ko) * 2020-06-08 2020-11-09 한국콜마주식회사 무기 점증제 및 유기 점증제를 포함하는 수분산 제형의 자외선 차단용 화장료 조성물
KR102574547B1 (ko) * 2020-10-28 2023-09-12 코스맥스 주식회사 무기분체를 안정적으로 내포하는 워터 드롭 매크로 에멀젼 화장료 조성물 및 이의 제조방법
KR102534801B1 (ko) * 2020-11-03 2023-05-19 아이큐어 주식회사 자외선 및 블루라이트 차단용 화장료 조성물
KR102532227B1 (ko) * 2020-11-03 2023-05-15 아이큐어 주식회사 자외선 및 블루라이트 차단용 유무기 복합소재 및 그 제조방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0619999A2 (fr) * 1993-04-14 1994-10-19 Tioxide Specialties Limited Compositions contenant des agents de protection solaire
KR100321188B1 (ko) * 1996-09-27 2002-01-19 데이비드 엠 모이어 안정한 차광 조성물
KR20040095267A (ko) * 2002-03-06 2004-11-12 다우 글로벌 테크놀로지스 인크. 화장품 제형의 제조방법 및 이를 위한 조성물
US20060280702A1 (en) * 2005-06-10 2006-12-14 Amcol International Corporation Stable sunscreen compositions containing zinc oxide
WO2016173927A1 (fr) * 2015-04-29 2016-11-03 Dsm Ip Assets B.V. Émulsions d'écran solaire topiques

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS501267B1 (fr) * 1970-12-28 1975-01-16
CN101674798B (zh) 2007-04-26 2015-03-25 株式会社资生堂 水包油型乳化组合物及其制备方法
ES2390008T3 (es) * 2008-07-16 2012-11-05 Dsm Ip Assets B.V. Uso de (etilendiamina)tetrametilenfosfonato pentasódico para suprimir la decoloración en composiciones tópicas
ES2559236T3 (es) * 2009-07-24 2016-02-11 Coreana Cosmetics Co., Ltd. Polvo de compuesto para bloquear simultáneamente rayos ultravioleta e infrarrojo y composición cosmética que utiliza lo mismo
EP2982363A1 (fr) * 2014-08-04 2016-02-10 Omya International AG Système à deux composants pour formulations cosmétiques

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0619999A2 (fr) * 1993-04-14 1994-10-19 Tioxide Specialties Limited Compositions contenant des agents de protection solaire
KR100321188B1 (ko) * 1996-09-27 2002-01-19 데이비드 엠 모이어 안정한 차광 조성물
KR20040095267A (ko) * 2002-03-06 2004-11-12 다우 글로벌 테크놀로지스 인크. 화장품 제형의 제조방법 및 이를 위한 조성물
US20060280702A1 (en) * 2005-06-10 2006-12-14 Amcol International Corporation Stable sunscreen compositions containing zinc oxide
WO2016173927A1 (fr) * 2015-04-29 2016-11-03 Dsm Ip Assets B.V. Émulsions d'écran solaire topiques

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