WO2018093731A3 - Method for treating lamivudine-resistant hepatitis b - Google Patents

Method for treating lamivudine-resistant hepatitis b Download PDF

Info

Publication number
WO2018093731A3
WO2018093731A3 PCT/US2017/061375 US2017061375W WO2018093731A3 WO 2018093731 A3 WO2018093731 A3 WO 2018093731A3 US 2017061375 W US2017061375 W US 2017061375W WO 2018093731 A3 WO2018093731 A3 WO 2018093731A3
Authority
WO
WIPO (PCT)
Prior art keywords
resistant hepatitis
lamivudine
treating
treating lamivudine
subject
Prior art date
Application number
PCT/US2017/061375
Other languages
French (fr)
Other versions
WO2018093731A2 (en
Inventor
Shu-chen HO WU
Kun-Shuan Huang
Ching-Chuan Chen
Ray-Ling Huang
Original Assignee
Jin Xin Biotechnology Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jin Xin Biotechnology Co., Ltd. filed Critical Jin Xin Biotechnology Co., Ltd.
Priority to CN201780070732.XA priority Critical patent/CN110072517A/en
Publication of WO2018093731A2 publication Critical patent/WO2018093731A2/en
Publication of WO2018093731A3 publication Critical patent/WO2018093731A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A method for treating lamivudine-resistant hepatitis B in a subject in need thereof comprises administering an effective amount of an aqueous extract of Bombax malabaricum DC. to the subject. The extract is obtained by extracting a flower sample of Bombax malabaricum DC. by water under 0.35-0.5 Kg/cm2G and 115-125°C for 1.5-3 hours.
PCT/US2017/061375 2016-11-15 2017-11-13 Method for treating lamivudine-resistant hepatitis b WO2018093731A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201780070732.XA CN110072517A (en) 2016-11-15 2017-11-13 The method for treating the viral hepatitis type b that how there is drug resistance to liver

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TW105137322 2016-11-15
TW105137322A TWI583389B (en) 2016-11-15 2016-11-15 A use of an extract of bombax malabaricum dc.

Publications (2)

Publication Number Publication Date
WO2018093731A2 WO2018093731A2 (en) 2018-05-24
WO2018093731A3 true WO2018093731A3 (en) 2019-06-13

Family

ID=59367434

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2017/061375 WO2018093731A2 (en) 2016-11-15 2017-11-13 Method for treating lamivudine-resistant hepatitis b

Country Status (3)

Country Link
CN (1) CN110072517A (en)
TW (1) TWI583389B (en)
WO (1) WO2018093731A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI583389B (en) * 2016-11-15 2017-05-21 景鑫生物科技有限公司 A use of an extract of bombax malabaricum dc.
TWI594760B (en) * 2017-01-16 2017-08-11 景鑫生物科技股份有限公司 A use of an extract of bombax malabaricum dc.
TWI612967B (en) * 2017-06-06 2018-02-01 景鑫生物科技股份有限公司 A use of an extract of asplenium australasicum (j. sm.) hook.
TW201907943A (en) * 2017-07-13 2019-03-01 景鑫生物科技股份有限公司 A use of an extract of Bombax malabaricum DC

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147969A1 (en) * 2001-10-05 2003-08-07 Tzu-Sheng Wu Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same
TWI583389B (en) * 2016-11-15 2017-05-21 景鑫生物科技有限公司 A use of an extract of bombax malabaricum dc.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612360B (en) * 2009-07-17 2010-07-21 肖嘉惠 Medicine for treating hepatitis, hepatocirrhosis and liver cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030147969A1 (en) * 2001-10-05 2003-08-07 Tzu-Sheng Wu Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same
TWI583389B (en) * 2016-11-15 2017-05-21 景鑫生物科技有限公司 A use of an extract of bombax malabaricum dc.

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
WANG ET AL.: "A new lignan with anti-HBV activity from the roots of Bombax ceiba", NATURAL PRODUCT RESEARCH, vol. 27, no. 15, August 2013 (2013-08-01), pages 1348 - 1352, XP055616462 *
WANJARI ET AL.: "Hepatoprotective and antioxidant activity of Bombax ceiba flowers against carbon tetrachloride-induced hepatotoxicity in rats", HEPATOMA RESEARCH, vol. 2, 1 June 2016 (2016-06-01), pages 144 - 150, XP055515976 *
ZHANG ET AL.: "Phenolic Compounds from the Flowers of Bombax malabaricum and Their Antioxidant and Antiviral Activities", MOLECULES, vol. 20, 2015, pages 19947 - 19957, XP055616465 *

Also Published As

Publication number Publication date
WO2018093731A2 (en) 2018-05-24
TWI583389B (en) 2017-05-21
TW201818953A (en) 2018-06-01
CN110072517A (en) 2019-07-30

Similar Documents

Publication Publication Date Title
WO2018093731A3 (en) Method for treating lamivudine-resistant hepatitis b
WO2017181141A3 (en) Combinations and methods comprising a capsid assembly inhibitor
MY178466A (en) A biostimulant formulation for improving plant growth and uses thereof
MX2016011152A (en) Pramipexole-containing transdermal patch for treatment of neurodegenerative disease.
WO2016201306A3 (en) Inhibitors of nucleotidyl transferases and use in herpes and hepatitis viral infections therefor
WO2018093735A3 (en) Method for treating hepatitis c
BR112015013218A2 (en) process of treating agricultural land with gas
IN2014MN01933A (en)
MX2013008754A (en) Process for preparation of a herbal extract.
MY156604A (en) Optimized extraction process for obtaining labisia pumila extract
NZ727066A (en) Preparation of a solid form of gadobenate dimeglumine
UA116466U (en) METHOD OF COMPLEX PROCESSING OF HAWTHORN FRUITS FOR OBTAINING MEANS WITH IMMUNOMODULATING ACTION
CN106967032B8 (en) Equipment for rapidly extracting flavone from plant stems and leaves and working method thereof
CN105230660A (en) Bacteriostatic agent for leather
RU2013143478A (en) METHOD FOR OBTAINING 7-HYDROXYROYLOLEANONE POSSESSING ANTIMICROBIAL ACTION
RU2019108739A (en) Antifungal, plant-based liquid extract
RU2018125189A (en) METHOD FOR PRODUCING IVAN-TEA EXTRACT
UA82981U (en) METHOD FOR PRODUCING DRY EXTRACT FROM Cayenne pepper WITH ANTICONVULSANT ACTION
WO2018026263A3 (en) A process for extracting irisresorcinol from labisia pumila
UA108399U (en) METHOD OF OBTAINING A LIPOPHILIC COMPLEX WITH ANTIMICROBIC ACTION
PH22016050024Y1 (en) Process for collecting oil from almaciga tree (agathis philippinensis) for conversion to biodiesel
GEP20135971B (en) Method of obtaining plant grow stimulator "alexin"
RU2012102194A (en) EXTRACTION OF IONS FROM AQUEOUS SOLUTIONS BY VEGETABLE OILS
RU2015155297A (en) METHOD FOR PRODUCING FODDER ADDITIVE BASED ON WOOD GREEN
TH161336A (en) Soluble chili extraction process And using the aforementioned processes

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17870714

Country of ref document: EP

Kind code of ref document: A2