WO2018080148A3 - Peg-기반 하이드로젤을 포함하는 3차원 세포배양 시스템 - Google Patents

Peg-기반 하이드로젤을 포함하는 3차원 세포배양 시스템 Download PDF

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WO2018080148A3
WO2018080148A3 PCT/KR2017/011802 KR2017011802W WO2018080148A3 WO 2018080148 A3 WO2018080148 A3 WO 2018080148A3 KR 2017011802 W KR2017011802 W KR 2017011802W WO 2018080148 A3 WO2018080148 A3 WO 2018080148A3
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peg
based hydrogel
cell culture
culture system
dimensional cell
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French (fr)
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WO2018080148A2 (ko
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이승태
임혜원
윤정임
김민성
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주식회사 세바바이오텍
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Publication of WO2018080148A3 publication Critical patent/WO2018080148A3/ko

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Abstract

본 발명은 PEG(polyethylene glycol)-기반 하이드로젤을 포함하는 3차원 세포배양 시스템에 관한 것으로서, 상기 PEG-기반 하이드로젤은 비닐술폰(vinylsulfone)이 결합된 PEG(polyethylene glycol)인 PEG-VS(polyethylene glycol-vinylsulfone)에 부착 펩타이드(adhesion peptide) 및 가교제(crosslinker)를 혼합하여 제조되며, 상기 시스템은 피부세포인 진피섬유아세포, 멜라노세포 또는 케라틴세포를 배양할 수 있어 피부세포의 활성을 측정하는데 유용하게 사용될 수 있다.
PCT/KR2017/011802 2016-10-31 2017-10-25 Peg-기반 하이드로젤을 포함하는 3차원 세포배양 시스템 WO2018080148A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0143486 2016-10-31
KR1020160143486A KR101910807B1 (ko) 2016-10-31 2016-10-31 Peg-기반 하이드로젤을 포함하는 3차원 세포배양 시스템

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WO2018080148A2 WO2018080148A2 (ko) 2018-05-03
WO2018080148A3 true WO2018080148A3 (ko) 2018-08-09

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109576213B (zh) * 2018-12-28 2022-07-12 杭州恩格生物医疗科技有限公司 一种黑色素细胞液的制备方法及其应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102053895B1 (ko) * 2019-02-01 2019-12-09 영남대학교 산학협력단 세포의 부착, 증식과 분화를 촉진하는 신규 펩티드 fnin3 및 이의 용도
KR102013218B1 (ko) * 2019-02-01 2019-08-22 영남대학교 산학협력단 세포의 부착, 증식과 분화를 촉진하는 신규 펩티드 fnin2 및 이의 용도
KR20230059380A (ko) * 2021-10-26 2023-05-03 강원대학교산학협력단 피부 복원용 3차원 스캐폴드

Citations (2)

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Publication number Priority date Publication date Assignee Title
US20050065281A1 (en) * 2001-11-07 2005-03-24 Mathias Lutolf Synthetic matrix for controlled cell ingrowth and tissue regeneration
US20120202263A1 (en) * 2011-02-03 2012-08-09 The Trustees Of The University Of Pennsylvania Bioactive Macromers and Hydrogels and Methods for Producing Same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050065281A1 (en) * 2001-11-07 2005-03-24 Mathias Lutolf Synthetic matrix for controlled cell ingrowth and tissue regeneration
US20120202263A1 (en) * 2011-02-03 2012-08-09 The Trustees Of The University Of Pennsylvania Bioactive Macromers and Hydrogels and Methods for Producing Same

Non-Patent Citations (3)

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Title
KRAEHENBUEHL, THOMAS P. ET AL.: "Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell -responsive PEG-hydrogel", BIOMATERIALS, vol. 29, 2008, pages 2757 - 2766, XP022615788 *
PATTERSON, J. ET AL.: "Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2", BIOMATERIALS, vol. 31, 2010, pages 7836 - 7845, XP027219014 *
ZHU, JUNMIN: "Bioactive modification of poly (ethylene glycol) hydrogels for tissue engineering", BIOMATERIALS, vol. 31, 2010, pages 4639 - 4656, XP055532113 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109576213B (zh) * 2018-12-28 2022-07-12 杭州恩格生物医疗科技有限公司 一种黑色素细胞液的制备方法及其应用

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KR101910807B1 (ko) 2018-10-23
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