WO2018010962A1 - Composition de soin buccal comprenant des particules composites contenant un germicide cationique - Google Patents

Composition de soin buccal comprenant des particules composites contenant un germicide cationique Download PDF

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Publication number
WO2018010962A1
WO2018010962A1 PCT/EP2017/066089 EP2017066089W WO2018010962A1 WO 2018010962 A1 WO2018010962 A1 WO 2018010962A1 EP 2017066089 W EP2017066089 W EP 2017066089W WO 2018010962 A1 WO2018010962 A1 WO 2018010962A1
Authority
WO
WIPO (PCT)
Prior art keywords
composite particles
composition according
composition
particles
cationic
Prior art date
Application number
PCT/EP2017/066089
Other languages
English (en)
Inventor
Somnath Das
Amitava Pramanik
Original Assignee
Unilever N.V.
Unilever Plc
Conopco, Inc., D/B/A Unilever
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever N.V., Unilever Plc, Conopco, Inc., D/B/A Unilever filed Critical Unilever N.V.
Priority to EP17736616.8A priority Critical patent/EP3484435A1/fr
Priority to BR112019000655A priority patent/BR112019000655A2/pt
Priority to CN201780043519.XA priority patent/CN109475473A/zh
Publication of WO2018010962A1 publication Critical patent/WO2018010962A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0254—Platelets; Flakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Definitions

  • said particles are flaky shaped, having a thickness of 30 to 50 nm.
  • the aforementioned composite particles are deposited into the teeth crevices, thereby replenishing lost enamel and brightening the teeth (whitening). Additional benefits are realized by the slow release of cationic germicide from the deposited composite particles. In particular, this slow release provides prolonged antimicrobial activity and effectively prevents the formation of biofilm.
  • the composite particles can be used as an abrasive component in toothpaste in the same way as common abrasives.
  • Yet another aspect of the invention relates to a method of preparing composite particles as defined herein, said method comprising the steps of:

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition de soin buccal comprenant des particules composites, lesdites particules contenant : un composant inorganique insoluble dans l'eau de formule Can(X)x(AOy)z (dans laquelle X est choisi parmi OH, F et Cl; A est choisi parmi C, P, Si et des combinaisons de ceux-ci; n vaut de 1 à 5; x vaut 0 ou 1; y vaut 3 ou 4; z vaut de 1 à 3; et un germicide cationique, lesdites particules étant en forme de paillettes et ayant une épaisseur de 15 à 80 nm. La composition de soin buccal empêche la formation de biofilm, facilite la reminéralisation de l'émail endommagé et assure un blanchiment prolongé des dents, ainsi qu'une activité antimicrobienne résiduelle prolongée.
PCT/EP2017/066089 2016-07-14 2017-06-29 Composition de soin buccal comprenant des particules composites contenant un germicide cationique WO2018010962A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP17736616.8A EP3484435A1 (fr) 2016-07-14 2017-06-29 Composition de soin buccal comprenant des particules composites contenant un germicide cationique
BR112019000655A BR112019000655A2 (pt) 2016-07-14 2017-06-29 composição,uso de uma composição e método de preparação de partículas compostas
CN201780043519.XA CN109475473A (zh) 2016-07-14 2017-06-29 包含含有阳离子杀菌剂的复合材料颗粒的口腔护理组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16179545.5 2016-07-14
EP16179545 2016-07-14

Publications (1)

Publication Number Publication Date
WO2018010962A1 true WO2018010962A1 (fr) 2018-01-18

Family

ID=56464048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/066089 WO2018010962A1 (fr) 2016-07-14 2017-06-29 Composition de soin buccal comprenant des particules composites contenant un germicide cationique

Country Status (4)

Country Link
EP (1) EP3484435A1 (fr)
CN (1) CN109475473A (fr)
BR (1) BR112019000655A2 (fr)
WO (1) WO2018010962A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100011492A1 (it) 2021-05-05 2022-11-05 Kalichem Srl Idrossiapatite biomimetica funzionalizzata

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273759A (en) 1979-05-18 1981-06-16 Colgate-Palmolive Company Antibacterial oral composition
US4933171A (en) * 1988-05-19 1990-06-12 Unilever Patent Holdings B.V. Oral compositions
KR20030016539A (ko) 2001-08-21 2003-03-03 엘지.필립스디스플레이(주) 음극선관용 편향요크
US20030175217A1 (en) 2000-06-16 2003-09-18 Christian Kropf Thixotropic oral and dental care agents
WO2007137606A1 (fr) 2006-05-30 2007-12-06 Coswell S.P.A. Nanoparticules biologiquement actives d'une hydroxyapatite substituée par des ions carbonate, procédé pour la préparation de celles-ci et compositions incorporant celles-ci
US20120251981A1 (en) 2011-03-22 2012-10-04 Klox Technologies Inc. Device and method for administering teeth whitening and antimicrobial compositions
EP2810917A1 (fr) 2013-06-04 2014-12-10 UAB Moksliniu Tyrimu Pletros Laboratorija Procédé d'obtention des nanocristaux d'hydroxyapatite de calcium de morphologie désirée

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US5900230A (en) * 1997-08-18 1999-05-04 Squigle, Inc. Dental products to treat and prevent periodontal disease
US6355229B1 (en) * 2001-06-27 2002-03-12 Church & Dwight Co., Inc. Oral composition containing cetylpyridinium chloride and guar hydroxypropyltrimonium chloride and method of using the same
US20040258630A1 (en) * 2003-06-23 2004-12-23 Boyd Thomas J. Antiplaque breath freshening consumable film
US20090013481A1 (en) * 2007-07-12 2009-01-15 Allwyn Colaco Composition to impart benefit agents to anionic substrates and methods of its use
WO2009091001A1 (fr) * 2008-01-17 2009-07-23 Kuraray Medical Inc. Composition orale dentaire
KR101229176B1 (ko) * 2010-07-19 2013-02-01 김기영 은 입자가 함유된 분말치약 조성물과 그 제조방법
CN104398390B (zh) * 2014-11-24 2017-10-03 浙江大学 牙本质底涂‑冲洗底涂剂及其方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273759A (en) 1979-05-18 1981-06-16 Colgate-Palmolive Company Antibacterial oral composition
US4933171A (en) * 1988-05-19 1990-06-12 Unilever Patent Holdings B.V. Oral compositions
US20030175217A1 (en) 2000-06-16 2003-09-18 Christian Kropf Thixotropic oral and dental care agents
KR20030016539A (ko) 2001-08-21 2003-03-03 엘지.필립스디스플레이(주) 음극선관용 편향요크
WO2007137606A1 (fr) 2006-05-30 2007-12-06 Coswell S.P.A. Nanoparticules biologiquement actives d'une hydroxyapatite substituée par des ions carbonate, procédé pour la préparation de celles-ci et compositions incorporant celles-ci
US20120251981A1 (en) 2011-03-22 2012-10-04 Klox Technologies Inc. Device and method for administering teeth whitening and antimicrobial compositions
EP2810917A1 (fr) 2013-06-04 2014-12-10 UAB Moksliniu Tyrimu Pletros Laboratorija Procédé d'obtention des nanocristaux d'hydroxyapatite de calcium de morphologie désirée

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
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NORBERTO ROVERI ET AL.: "Evolving application of biomimetic nanostructured hydroxyapatite", NANOTECHNOLOGY, SCIENCE AND APPLICATIONS, 1 November 2010 (2010-11-01), pages 107
NORBERTO ROVERI ET AL.: "Surface Enamel Remineralization: Biomimetic Apatite Nanocrystals and Fluoride Ions Different Effects", JOURNAL OF NANOMATERIALS, vol. 2, no. 2, January 2009 (2009-01-01), pages 1149 - 9
NORBERTO ROVERI ET AL: "Evolving application of biomimetic nanostructured hydroxyapatite", NANOTECHNOLOGY, SCIENCE AND APPLICATIONS, 1 November 2010 (2010-11-01), pages 107, XP055302872, DOI: 10.2147/NSA.S9038 *
NORBERTO ROVERI ET AL: "Surface Enamel Remineralization: Biomimetic Apatite Nanocrystals and Fluoride Ions Different Effects", JOURNAL OF NANOMATERIALS, vol. 2, no. 2, 1 January 2009 (2009-01-01), US, pages 1149 - 9, XP055302888, ISSN: 1687-4110, DOI: 10.1177/10454411950060020701 *
SORIANO DE SOUZA ET AL.: "Adsorption of chlorhexidine on synthetic hydroxyapatite and in vitro biological activity", COLLOIDS AND SURFACES B: BIOINTERFACES, vol. 87, 2011, pages 310 - 318
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Also Published As

Publication number Publication date
CN109475473A (zh) 2019-03-15
BR112019000655A2 (pt) 2019-04-24
EP3484435A1 (fr) 2019-05-22

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