WO2017219805A1 - 含有双唑草酮的复配除草组合物及其使用方法 - Google Patents

含有双唑草酮的复配除草组合物及其使用方法 Download PDF

Info

Publication number
WO2017219805A1
WO2017219805A1 PCT/CN2017/084916 CN2017084916W WO2017219805A1 WO 2017219805 A1 WO2017219805 A1 WO 2017219805A1 CN 2017084916 W CN2017084916 W CN 2017084916W WO 2017219805 A1 WO2017219805 A1 WO 2017219805A1
Authority
WO
WIPO (PCT)
Prior art keywords
active ingredient
herbicidal composition
composition containing
glyphosate
compound
Prior art date
Application number
PCT/CN2017/084916
Other languages
English (en)
French (fr)
Inventor
彭学岗
金涛
张景远
Original Assignee
青岛清原抗性杂草防治有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 青岛清原抗性杂草防治有限公司 filed Critical 青岛清原抗性杂草防治有限公司
Priority to CA3029080A priority Critical patent/CA3029080C/en
Priority to US16/312,770 priority patent/US20190216089A1/en
Priority to AU2017280298A priority patent/AU2017280298B2/en
Publication of WO2017219805A1 publication Critical patent/WO2017219805A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles

Definitions

  • the invention relates to a compound herbicidal composition containing oxazolone and a using method thereof, and belongs to the field of pesticides.
  • Glyphosate molecular formula: C 3 H 8 NO 5 P, chemical name: N-(phosphonomethyl)glycine
  • a herbicide developed by Monsanto, USA is a highly efficient, low-toxic, broad-spectrum And post-emergence herbicides for non-selective foliar application, which mainly inhibit the enol acetone-based valerin phosphate synthase in plants, thereby inhibiting the conversion of valerin to phenylalanine, tyrosine and color ammonia.
  • the conversion of acid interferes with protein synthesis, leading to plant death.
  • Glyphosate is absorbed into the plant through stems and leaves and transmitted to the whole body tissues, inhibiting the biosynthesis of amino acids, interfering with photosynthesis and killing them. Glyphosate protects more than 40 families of monocotyledonous and dicotyledonous, annual and perennial, herbaceous and shrub species. Glyphosate quickly loses its activity when it is combined with metal ions such as iron and aluminum, and has no adverse effects on the seeds and soil microorganisms in the soil.
  • Glufosinate ammonium molecular formula: C 5 H 15 N 2 O 4 P, chemical name: 4-[hydroxy(methyl)phosphonoyl]-DL-homoalanine
  • Hearst Company in the 1980s It has been successfully developed and is a broad-spectrum contact herbicide. Its systemic action is not strong. It is used in orchards, vineyards, non-cultivated land, potato fields, etc. to control annual and perennial dicotyledonous and grassy weeds.
  • Glutamine synthetase plays an important role in the nitrogen metabolism of plants. It is an important detoxifying enzyme in plants, which can relieve the toxicity of ammonia released by nitrate reduction, amino acid degradation and photorespiration.
  • glufosinate The target enzyme of glufosinate is glutamine synthetase (GS).
  • GS glutamine synthetase
  • Glufosinate inhibits the activity of plant GS, causing dysregulation of plant nitrogen metabolism, lack of essential amino acids, and eventually leading to excessive glucose and poisoning in the cells, followed by chlorophyll. Disintegration, plant death.
  • glyphosate Compared with glyphosate, glyphosate is ineffective against malignant weeds such as amaranth, chlorpyrifos, etc.
  • Glufosinate has special effects.
  • HPPD p-hydroxyphenylpyruvate dioxygenase
  • the HPPD-targeted inhibitor has a broad-spectrum herbicidal activity and can simultaneously control broad-leaved weeds in broad-leaved crops. It can be used both before or after bud, with high activity, low residual, and environmental phase. Good capacitance and safe use. This type of herbicide appears later, the development of resistance is slower than other mechanisms of action, and there is no cross-resistance with other commonly used herbicides, which can be an important solution for the management of resistant weeds.
  • the invention provides a compound herbicidal composition containing oxazolone and a method for using the same, and the cycloflufenone has synergistic effect with glyphosate or glufosinate, and has excellent activity for controlling resistant weeds.
  • the active ingredient B is glyphosate or glufosinate.
  • the weight ratio of the active ingredient A to the active ingredient B is 1:100-1, preferably 1:60-1.
  • the concentration of the active ingredients A and B in the compound herbicidal preparation of the invention is usually from 0.001 to 98% by weight, preferably from 0.01 to 90% by weight.
  • the active ingredient is usually present in a concentration of from 5 to 98% by weight, preferably from 10 to 90% by weight, more preferably from 20 to 75% by weight.
  • the compounded herbicidal composition is mixed with a usual auxiliary agent of at least one formulation technique to obtain a compounded herbicidal preparation.
  • auxiliary agents commonly used in the formulation technology include liquid carriers, solid carriers, dispersing agents, emulsifiers, stabilizers, antifreeze agents, thickeners and other known substances which are beneficial to the stability and efficacy of the active ingredients in the preparation, preferably pesticides.
  • the various ingredients, specific ingredients and amounts which are commonly used or allowed to be used, are determined by experiments according to the different properties of the various preparations.
  • Liquid carriers suitable for the preparation of the compound herbicidal preparations according to the invention are preferably aromatic hydrocarbons, aliphatic hydrocarbons, particularly preferably polar solvents, such as alcohols and their ethers and esters, in addition to vegetable oils and methyl soluble fibers; Mixtures are also suitable.
  • the solid carrier suitable for preparing the compound herbicidal preparation of the present invention is preferably diatomaceous earth, aluminum magnesium silicate, activated clay, kaolin, clay, gypsum, bentonite, white carbon, light calcium carbonate, limestone, wood chips, corn starch, One or more of soluble starches.
  • Dispersing agents suitable for preparing the compound herbicidal preparation of the present invention are preferably alkylnaphthalenesulfonate, bis(alkyl)naphthalenesulfonate formaldehyde condensate, naphthalenesulfonic acid formaldehyde condensate, alkylphenol polyoxyethylene phosphate , alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether, castor oil ethylene oxide adduct, ethylene oxide-epoxy Propane block copolymer, alkylphenol ethoxylate ether condensation condensate, octylphenol polyoxyethylene ether sulfate, and methyl cellulose.
  • sodium lignosulfonate for example, one or more of sodium lignosulfonate, calcium lignosulfonate, sodium methylnaphthalenesulfonate formaldehyde condensate, sodium naphthalenesulfonate formaldehyde condensate, and sodium methylene naphthalenesulfonate.
  • Suitable emulsifiers for preparing the compound herbicidal preparations of the invention are preferably anionic and/or nonionic emulsifiers, such as alkylphenol ethoxylates, alkylphenol polyoxyethylene polyoxypropylene ethers, benzylphenol polyoxyethylenes.
  • anionic and/or nonionic emulsifiers such as alkylphenol ethoxylates, alkylphenol polyoxyethylene polyoxypropylene ethers, benzylphenol polyoxyethylenes.
  • carboxymethylcellulose, ethylene glycol, propylene glycol and the like which are usually used in the form of auxiliary agents are used.
  • the compounding herbicidal composition and the auxiliary agent commonly used in the formulation technology can be formulated into any dosage form allowed in agriculture, and the present invention preferably
  • the dosage form is liquid agent, wettable powder, soluble powder, soluble granule, emulsifiable concentrate, water suspension agent, dispersible oil suspension agent, microcapsule, microemulsion, water emulsion, suspension emulsion, water dispersible granule, capsule suspension Mixture (ZC), ultra low volume liquid agent, seed coating agent.
  • the auxiliary agents used are: a dispersing agent, an emulsifier, a wetting agent, a thickener, a preservative, an antifoaming agent and an antifreezing agent; wherein: the dispersing agent is selected from the group consisting of polycarboxylates and lignosulfonates.
  • alkyl naphthalene sulfonate alkyl naphthalene sulfonate
  • emulsifier selected from the agricultural milk 700# (common name: alkylphenol formaldehyde resin polyoxyethylene ether), agricultural milk 2201, Sipan-60# (common name: sorbitol monostearyl) Acid ester), emulsifier T-60 (common name: sorbitan monostearate polyoxyethylene ether), agricultural milk 1601# (common name: phenethyl phenol polyoxyethylene polyoxypropylene ether);
  • the wetting agent is selected from the group consisting of alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, alkylphenol polyoxyethylene ether phosphate, phenethyl phenol polyoxyethylene ether phosphate, alkyl sulfate, alkyl sulfonic acid Salt, naphthalene sulfonate, TERSPERSE 2
  • the auxiliary agents used are: dispersing agents, emulsifiers, wetting agents, thickeners, antifreeze agents, stabilizers and dispersion media; wherein: the dispersing agent is selected from the group consisting of polycarboxylates and lignin sulfonates.
  • the auxiliary agents used are: a dispersing agent, a wetting agent and a solid carrier; wherein: the dispersing agent is selected from the group consisting of polycarboxylates, lignosulfonates, alkylnaphthalenesulfonates; Alkyl sulfate, alkyl sulfonate, naphthalene sulfonate; solid support selected from the group consisting of ammonium sulfate, urea, sucrose, glucose, diatomaceous earth, kaolin, white carbon black, light calcium carbonate, talc, attapulgite And clay.
  • the dispersing agent is selected from the group consisting of polycarboxylates, lignosulfonates, alkylnaphthalenesulfonates; Alkyl sulfate, alkyl sulfonate, naphthalene sulfonate; solid support selected from the group consisting of ammonium sulfate,
  • the auxiliary agents used are: a dispersing agent, a wetting agent, a disintegrating agent, a binder and a solid carrier; wherein: the dispersing agent is selected from the group consisting of polycarboxylates, lignosulfonates, alkylnaphthalenes Sulfonate, alkylphenol ethoxylate, EO/PO block polyether; wetting agent is selected from the group consisting of alkyl sulfate, alkyl sulfonate, naphthalene sulfonate, sodium lignosulfonate, fatty alcohol Oxyethylene ether, alkylphenol ethoxylate; disintegrant selected from ammonium sulfate, sodium sulfate, sodium chloride, ammonium chloride, urea, sucrose, glucose, carboxymethyl Base cellulose, soluble starch, polyvinylpyrrolidone; the binder is selected from the group consisting of polycarboxylates, lignos
  • the present invention also provides a method of controlling undesirable plants comprising applying the formulated herbicidal compositions to a growing place and/or leaves and/or stems of undesirable plants.
  • the undesired plants are grass weeds, broadleaf weeds, and sedge weeds.
  • grass weeds Such as genus, genus, genus, genus, genus, oats, foxtail, genus, ryegrass, genus Solanum, genus, genus, genus, genus, genus, genus Genus, yellow flower genus, Xanthium, genus, genus, sweet potato, genus Artemisia, Poria, Amaranthus and Pomna.
  • the active ingredients of the invention may also be administered in combination with one or more other herbicides to control a wider range of undesirable vegetation.
  • the active ingredient can be formulated with other herbicides or with other herbicides.
  • the invention adopts glyphosate or glufosinate mixed with oxazolone, has good activity for controlling weeds in the field, effectively reduces the damage of weeds on field crops, improves crop yield and improves quality.
  • Glyphosate or glufosinate is mixed with oxazolone, and the herbicidal spectrum has certain complementarity and synergy. The combination of the two helps to reduce the amount of each component, reduce the phytotoxicity, reduce residual activity, and delay The occurrence and development of herbicide resistance.
  • Descurainia sophia and Capsella bursa-pastoris were collected from the wheat field of the test site of Huangdao District, Shandong City in 2015.
  • the above weeds are cultured by pot culture. It is placed in an enamel pan with 180*140mm plastic nutrient bowl, and the surface soil (4/5) which has been air-dried and screened from the farmland is collected. The soil moisture is controlled at 20% at the beginning, and the weeds are selected to be full and uniform.
  • the seeds were immersed in warm water at 25 ° C for 6 hours, germinated in a 28 ° C biochemical incubator (dark), and the white weed seeds were evenly placed on the soil surface, and then the soil was 0.7 cm. After the treatment, the medicine is placed in a controllable solar greenhouse, and a certain amount of water is regularly added to the enamel tray to keep the soil moist.
  • Glufosinate is a herbicide that is absorbed by stems and leaves and transmitted to various parts of the plant. Glufosinate is different from glyphosate. Glufosinate is a contact-weak herbicide with weak internal absorption and no conduction. It only produces drug spots at the contact site and has a fast action.
  • the oxazolone has a broad spectrum of herbicidal activity and can simultaneously control broadleaf weeds, mainly used after germination.
  • Each treatment was repeated 4 times, and each time 3 pots were treated, 20 seeds of weed seeds were planted per pot, and 60 plants per treatment.
  • the cultured test materials were evenly placed on a platform with an area of 0.5 m 2 , and sprayed with a 3WP-2000 type walking spray tower, and the spray amount was 30 kg/ha.
  • the spray pressure was 0.3 MPa. After all the liquid medicines have been sprayed, close the air valve. After 30 seconds, open the spray tower door and take out the nutrient bowl. Then open the air valve, spray 50ml of water, and clean the spray tube.
  • the whole seedlings of the living weeds were cut along the surface of the soil with a blade, and the fresh weight of the weeds was weighed by an analytical balance. For dead weeds, the fresh weight is zero.
  • the investigation was conducted 20 days after the treatment, and a total of 1 investigation was conducted.
  • E measured inhibition rate
  • the E-E0 value is greater than 10% for synergism, less than -10% for antagonism, and between -10% and 10% for additive effect. According to the actual control effect and the characteristics of the herbicide, the balance of the formula and other factors determine the best ratio.
  • X is the fresh weight inhibition rate when the amount of glyphosate or glufosinate is P
  • Y is the fresh weight inhibition rate when the amount of oxazolone is Q.
  • Type of joint action The test results show that (Table 1, Table 2), the combination of glyphosate or glufosinate and oxazolone combined treatment of two kinds of weeds E-E0 value ⁇ 0, showing a certain Increase the trend of drug efficacy.
  • the dosage range and content of the selected preparation should be properly considered in the processed dosage form. If processed into a dispersible oil suspending agent, the total content of the preparation should not be too high, otherwise the viscosity is too large to be processed, and a relatively small ratio range is generally selected. If the two agents are processed into wettable powders, water-dispersible granules or aqueous suspensions, the ratio can be broader.
  • Medicinal evaluation The results of the determination of the herbicidal effect of glyphosate on the oxaloquinone against the wormwood and amaranth are shown in Table 1. It can be seen that glyphosate and oxazolone have a synergistic effect on the 675+15, 675+30, 900+15 compound composition, and the E-E0 values correspond to 20.5, 10.7, and 12.3, respectively; For the leek, the combination of 675+15, 675+30, and 900+15 showed synergistic effect, and the E-E0 values corresponded to 21.9, 11.6, and 11.9, respectively.
  • Medicinal evaluation The results of the determination of the herbicidal effect of glufosinate on diazepam against sage and amaranth are shown in Table 2. It can be seen that glufosinate and oxazolone have synergistic effects on the planting of Artemisia scoparia with 300+15, 300+30 and 450+15, and their E-E0 values correspond to 23.4, 12.9 and 13.3, respectively; For the amaranth, the combination of 300+15, 300+30, and 450+15 showed synergistic effect, and the E-E0 values corresponded to 23.8, 14.3, and 12.3, respectively.
  • Formulation composition 1% oxadiazone + 30% glyphosate + 12% EO-PO block polyether + 2% naphthalene sulfonate wetting agent + 0.2% xanthan gum + 5% glycerol + Water complements.
  • the above water suspension processing equipment mixing tank, colloid mill, sand mill, shearing machine and the like.
  • Formulation composition 2% oxadiazone + 20% glufosinate + 5% phenethyl phenol polyoxyethylene ether phosphate triethanolamine salt + 2% fatty alcohol polyoxyethylene ether + 0.15% xanthan gum + 5% Glycerol + water to make up.
  • the above water suspension processing equipment mixing tank, colloid mill, sand mill, shearing machine and the like.
  • Formulation composition 1% oxaconazole + 20% glyphosate + 2% calcium dodecylbenzene sulfonate + 4% phenethyl phenol polyoxyethylene ether phosphate triethanolamine salt + 5% fatty alcohol polyoxygen Vinyl ether + 4% castor oil polyoxyethylene ether + 2.2% organic bentonite + methyl oleate to make up.
  • the above dispersible oil suspension processing equipment mixing tank, colloid mill, sand mill, shearing machine and the like.
  • the above dispersible oil suspension agent processing process all materials are put into the mixing kettle, stirred and mixed, then passed through the colloid mill, then enter the sand mill three-stage sanding, and finally cut evenly in the shearing machine, after passing the test, transfer To the tank filling.
  • Formulation composition 1% oxaconazole + 20% glufosinate + 4% sodium sec-butyl dioctyl sulfonate + 6% nonylphenol ethoxylate + 7% castor oil polyoxyethylene ether + 2 % organic bentonite + 10% soybean oil + methyl oleate to make up.
  • the above dispersible oil suspension processing equipment mixing tank, colloid mill, sand mill, shearing machine and the like.
  • the above dispersible oil suspension agent processing process all materials are put into the mixing kettle, stirred and mixed, then passed through the colloid mill, then enter the sand mill three-stage sanding, and finally cut evenly in the shearing machine, after passing the test, transfer To the tank filling.
  • composition of the formula is: 2% oxazolone + 60% glyphosate + 10% naphthalene sulfonate dispersant + 5% pull powder + 5% precipitation method white carbon black + kaolin complement.
  • the above wettable powder processing equipment a mechanical pulverizer and a jet mill.
  • the above-mentioned wettable powder processing process the original drug, the auxiliary agent, the filler and the like are put into a mechanical pulverizer, and then passed through the airflow pulverizer, and the sample is tested and qualified for use.
  • Formulation composition 3% oxaconazole + 40% glufosinate + 10% sodium lignin sulfonate dispersant + 2.5% sodium lauryl sulfate + 10% precipitation method white carbon black + calcium bentonite complement
  • the above wettable powder processing equipment a mechanical pulverizer and a jet mill.
  • the above-mentioned wettable powder processing process the original drug, the auxiliary agent, the filler and the like are put into a mechanical pulverizer, and then passed through the airflow pulverizer, and the sample is tested and qualified for use.
  • Formulation composition 2% oxadiazone + 60% glyphosate + 20% EO-PO block polyether dispersant + 5% pull powder + 5% urea + ammonium sulfate make up
  • the original drug, the auxiliary agent, the filler and the like are put into a mechanical pulverizer, and then passed through the airflow pulverizer, and the sample is tested and qualified for use.
  • Formulation composition 2% oxaconazole + 20% glufosinate + 20% naphthalene sulfonate dispersant + 5% sodium lauryl sulfate + 1% precipitation method white carbon black + anhydrous sodium sulfate
  • the above-mentioned soluble powder processing process the original medicine, the auxiliary agent, the filler and the like are put into a mechanical pulverizer, and then the air flow is pulverized. Machine, sample and test after passing the test.
  • composition of the formula is: 2% oxadiazone + 60% glyphosate + 10% polycarboxylate dispersant + 5% pull-open powder + 1% disintegrant polyvinyl alcohol + filler diatomaceous earth to make up.
  • the above water dispersible granule processing equipment a jet mill, a coulter mixer, a basket granulator, a drying box, a screening machine, and the like.
  • the above water-dispersible granule processing process the above materials are uniformly mixed and pulverized by air flow, added with water to knead and granulate, then dried, and finally sieved to obtain a finished product.
  • Formulation composition 2% oxaconazole + 20% glufosinate +15% naphthalene sulfonate dispersant + 2.5% sodium dodecyl benzene sulfonate +1% disintegrant PEG-4000+ Filled kaolin is used to make up.
  • the above water dispersible granule processing equipment a jet mill, a coulter mixer, a basket granulator, a drying box, a screening machine, and the like.
  • the above water-dispersible granule processing process the above materials are uniformly mixed and pulverized by air flow, added with water to knead and granulate, then dried, and finally sieved to obtain a finished product.
  • composition of the formula is: 2% oxazolone + 60% glyphosate + 12% polycarboxylate dispersant + 5% pull-open powder + 1% disintegrant polyvinyl alcohol + filler urea to make up.
  • the above-mentioned soluble granule processing equipment a jet mill, a coulter mixer, a basket granulator, a drying box, a screening machine, and the like.
  • the above-mentioned soluble granule processing process the above materials are uniformly mixed and pulverized by air flow, water is added to kneading granulation, then dried, and finally sieved to obtain a finished product.
  • Formulation composition 2% oxaconazole + 40% glufosinate +15% naphthalene sulfonate dispersant + 2.5% sodium dodecyl benzene sulfonate +1% disintegrant PEG-4000+ Filled with anhydrous sodium sulfate.
  • the above-mentioned soluble granule processing equipment a jet mill, a coulter mixer, a basket granulator, a drying box, a screening machine, and the like.
  • the above-mentioned soluble granule processing process the above materials are uniformly mixed and pulverized by air flow, water is added to kneading granulation, then dried, and finally sieved to obtain a finished product.
  • Control agent Glyphosate, glufosinate and oxadiazepine compound composition, developed and produced by Qingdao Nongguan Pesticide Co., Ltd.
  • Control agent 30% glyphosate water; 200g/L glyphosate soluble solution (commercially available); 10% oxadiazepine OD (Qingdao Nongguan Pesticides Co., Ltd.).
  • the weeds were investigated as weeds, such as sage, amaranth, amaranth, and purslane.
  • the fresh weight of weeds was investigated 20 days and 40 days after application.

Abstract

提供一种含有双唑草酮的复配除草组合物及其使用方法。该复配除草组合物包含活性成分A和B，其中活性成分A为双唑草酮，活性成分B为草甘膦或草铵膦，二者重量配比为1:100-1，优选1:60-1。该复配除草组合物具有增效作用，对于防治抗性杂草具有极好活性。

Description

含有双唑草酮的复配除草组合物及其使用方法 技术领域
本发明涉及一种含有双唑草酮的复配除草组合物及其使用方法，属于农药领域。
背景技术
草甘膦(Glyphosate)，分子式：C3H8NO5P，化学名称：N-(膦酸甲基)甘氨酸，是由美国孟山都公司开发的除草剂，是一种高效、低毒、广谱和内吸传导非选择性叶面喷施的芽后除草剂，主要抑制植物体内的烯醇丙酮基莽草素磷酸合成酶，从而抑制莽草素向苯丙氨酸、酪氨酸及色氨酸的转化，使蛋白质合成受到干扰，导致植物死亡。草甘膦是通过茎叶吸收进入植物体内，并传导至全身组织，抑制氨基酸的生物合成，干扰光合作用，使之枯死。草甘膦可防除单子叶和双子叶、一年生和多年生、草本和灌木等40多科的植物。草甘膦入土后很快与铁、铝等金属离子结合而失去活性，对土壤中潜藏的种子和土壤微生物无不良影响。
草铵膦(Glufosinate ammonium)，分子式：C5H15N2O4P，化学名称：4-[羟基(甲基)膦酰基]-DL-高丙氨酸，是由赫斯特公司80年代开发成功，属广谱触杀型除草剂，内吸作用不强，用于果园、葡萄园、非耕地、马铃薯田等防治一年生和多年生双子叶及禾本科杂草。谷氨酰胺合成酶在植物的氮代谢中起重要作用，它是植物中一个重要的解毒酶，其可以解除由硝酸盐还原、氨基酸降解及光呼吸中释放出的氨的毒性。草铵膦的靶标酶正是谷氨酰胺合成酶(GS)，草铵膦抑制植物GS的活性，造成植物氮代谢失调，必需氨基酸缺乏，最终导致细胞内氨的含量过量而中毒，随之叶绿素解体，植物死亡。与草甘膦相比，对抗恶性杂草如荠菜、小飞蓬等，草甘膦无效，草铵膦有特效。
HPPD，对羟基苯基丙酮酸双氧化酶，是20世纪90年代确定的除草剂作用新靶标。以HPPD为靶标的抑制剂具有广谱的除草活性，能同时防除阔叶作物中的阔叶杂草，既可在芽前使用，也可以在芽后使用，具有活性高、残留低、环境相容性好、使用安全的特点。这一类除草剂出现较晚，抗性发展较其他作用机制的慢，而且与常用的其他作用机制的除草剂不存在交互抗性，可以作为抗性杂草管理的重要解决方案。
发明内容
本发明提供一种含有双唑草酮的复配除草组合物及其使用方法，环吡氟草酮与草甘膦或草铵膦具有增效作用，对于防治抗性杂草具有极好活性。
本发明的技术方案为：
一种含有双唑草酮的复配除草组合物，包括活性成分A和B，所述的活性成分A为双唑 草酮
Figure PCTCN2017084916-appb-000001
活性成分B为草甘膦或草铵膦。
活性成分A与活性成分B重量配比为1:100-1，优选1:60-1。
活性成分A和B在本发明的复配除草制剂中的浓度通常为0.001-98wt％，优选使用0.01-90wt％的浓度。在设计用作浓缩物的制剂中，有效成分的存在浓度通常为5-98wt％，优选10-90wt％，更优选20-75wt％。
采用所述复配除草组合物与至少一种制剂技术常用助剂混合，得到复配除草制剂。
所述制剂技术常用助剂包括液体载体、固体载体、分散剂、乳化剂、稳定剂、防冻剂、增稠剂及其它有益于有效成分在制剂中稳定和药效发挥的已知物质，优选农药中常用或允许使用的各种成分，具体成分和用量根据各种制剂不同的性能而定，通过试验确定。
适合制备本发明所述复配除草制剂的液体载体优选芳烃、脂肪烃，尤其优选极性溶剂，如醇类以及它们的醚和酯，此外还可选择植物油和甲基溶纤维；同时，不同液体的混合物也是适用的。
适合制备本发明所述复配除草制剂的固体载体优选硅藻土、硅酸铝镁、活性白土、高岭土、粘土、石膏、膨润土、白炭黑、轻质碳酸钙、石灰石、木屑、玉米淀粉、可溶性淀粉中的一种或多种。
适合制备本发明所述复配除草制剂的分散剂优选烷基萘磺酸盐、双(烷基)萘磺酸盐甲醛缩合物、萘磺酸甲醛缩合物、烷基酚聚氧乙烯基磷酸盐、烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯醚磷酸酯、烷基酚聚氧乙烯醚、蓖麻油环氧乙烷加成物、环氧乙烷-环氧丙烷嵌段共聚物、烷基酚聚氧乙烯醚甲醛缩合污、辛基酚聚氧乙烯基醚硫酸盐和甲基纤维素。例如木质素磺酸钠、木质素磺酸钙、甲基萘磺酸钠甲醛缩合物、萘磺酸钠甲醛缩合物、亚甲基萘磺酸钠中的一种或多种。
适合制备本发明所述复配除草制剂的乳化剂优选阴离子和/或非离子型乳化剂，如烷基酚聚氧乙烯醚、烷基酚聚氧乙烯聚氧丙烯醚、苄基酚聚氧乙烯醚、聚氧乙烯脂肪酸酯、聚氧乙烯脂肪醇醚、聚氧乙烯脂肪胺、烷基酚聚乙二醇醚中的一种或多种。
其它添加剂，采用通常以助剂形式使用的羧甲基纤维素，乙二醇和丙二醇等。
所述复配除草组合物与制剂技术常用助剂可配制成农业上允许的任意剂型，本发明优选 的剂型为液剂、可湿性粉剂、可溶性粉剂、可溶性粒剂、乳油、水悬浮剂、可分散油悬浮剂、微囊剂、微乳剂、水乳剂、悬浮乳剂、水分散粒剂、胶囊水悬混剂(ZC)、超低容量液剂、种衣剂。
对悬浮剂，使用的助剂有：分散剂、乳化剂、润湿剂、增稠剂、防腐剂、消泡剂和防冻剂；其中：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐；乳化剂选自农乳700#(通用名：烷基酚甲醛树脂聚氧乙烯醚)、农乳2201、斯盘-60#(通用名：山梨醇酐单硬脂酸酯)、乳化剂T-60(通用名：失水山梨醇单硬脂酸酯聚氧乙烯醚)、农乳1601#(通用名：苯乙基苯酚聚氧乙烯聚氧丙烯醚)；润湿剂选自烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯基醚磷酸酯、苯乙基酚聚氧乙烯基醚磷酸酯、烷基硫酸盐、烷基磺酸盐、萘磺酸盐、TERSPERSE2500(美国亨斯迈公司出品)；增稠剂选自黄原胶、聚乙烯醇、膨润土、硅酸镁铝；防腐剂选自甲醛、苯甲酸、苯甲酸钠；消泡剂为有机硅类消泡剂；防冻剂选自乙二醇、丙二醇、甘油、尿素、无机盐类(如氯化钠)。
对可分散油悬浮剂，使用的助剂有：分散剂、乳化剂、润湿剂、增稠剂、防冻剂、稳定剂和分散介质；其中：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐(扩散剂NNO)、TERSPERSE2425；乳化剂选自BY(蓖麻油聚氧乙烯醚)系列乳化剂(BY-110、BY-125、BY-140)农乳700#(通用名：烷基酚甲醛树脂聚氧乙烯醚)、农乳2201、斯盘-60#(通用名：山梨醇酐单硬脂酸酯)、吐温-60#(通用名：失水山梨醇单硬脂酸酯聚氧乙烯醚)、农乳1601#(通用名：苯乙基苯酚聚氧乙烯聚氧丙烯醚)、TERSPERSE4894；润湿剂选自烷基酚聚氧乙烯基醚甲醛缩合物硫酸盐、烷基酚聚氧乙烯醚磷酸酯、苯乙基酚聚氧乙烯基醚磷酸酯、烷基硫酸盐、烷基磺酸盐、萘磺酸盐、TERSPERSE2500；增稠剂选自白炭黑、聚乙烯醇、膨润土、硅酸镁铝；防冻剂选自乙二醇、丙二醇、甘油、尿素、无机盐类(如氯化钠)；稳定剂选自环氧大豆油、环氧氯丙烷、磷酸三苯酯；分散介质选自大豆油、菜籽油、玉米油、油酸甲酯、柴油、机油、矿物油。
对可湿性粉剂，使用的助剂有：分散剂、润湿剂和固体载体；其中：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐；润湿剂选自烷基硫酸盐、烷基磺酸盐、萘磺酸盐；固体载体选自硫酸铵、尿素、蔗糖、葡萄糖、硅藻土、高岭土、白炭黑、轻质碳酸钙、滑石粉、凹凸棒土、陶土。
对于水分散粒剂，使用的助剂有：分散剂、润湿剂、崩解剂、粘结剂和固体载体；其中：分散剂选自聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐、烷基酚聚氧乙烯醚、EO/PO嵌段聚醚；润湿剂选自烷基硫酸盐、烷基磺酸盐、萘磺酸盐、木质素磺酸钠、脂肪醇聚氧乙烯醚、烷基酚聚氧乙烯醚；崩解剂选自硫酸铵、硫酸钠、氯化钠、氯化铵、尿素、蔗糖、葡萄糖、羧甲 基纤维素、可溶淀粉、聚乙烯吡咯烷酮；粘结剂选自聚乙烯醇、可溶性淀粉、糊精、黄原胶、羧甲基(乙基)纤维素类；固体载体选自硅藻土、高岭土、白炭黑、轻质碳酸钙、滑石粉、凹凸棒土、陶土。
本发明还提供一种防治不希望有的植物的方法，包括将所述的复配除草组合物施用于不希望有的植物的生长场所和/或叶和/或茎上。
所述不希望有的植物为禾本科杂草、阔叶杂草及莎草科杂草。如繁缕属、豆瓣菜属、剪股颖属、马唐属、燕麦属、狗尾草属、欧白芥属、黑麦草属、茄属、雀麦属、看麦娘属、母菊属、茼麻属、黄花稔属、苍耳属、苋属、藜属、番薯属、茼蒿属、猪殃殃属、堇菜属和婆婆纳属。具体地，如扁杆藤草、牛毛毡、日本藨草、水莎草、碎米莎草、异型莎草、播娘蒿、马唐、荠菜、千金子、狗尾草、早熟禾、牛毛毡、萤蔺、鸭舌草、节节菜、水马齿、水车前、荆三棱、野慈姑、眼子菜、猪殃殃、荠菜、刺儿菜、苍耳、香附子、铁苋菜、藜、刺苋及枝苋、遏兰菜、唐松草、马齿苋等。
本发明的有效成分还可以与一种或多种其它除草剂联合施用以控制更广范围的不期望的植被。当与其它除草剂联合使用时，有效成分可以与其它除草剂配制、或与其它除草剂相续施用。本发明的有效成分与下述除草剂混配同样可以取得增效的技术效果。
上述可以与本发明的有效成分联合使用的其他种类除草剂包括：2,4-D，刈草胺，三氟羧草醚，苯草醚，甲草胺，磺氨磺隆氯氨吡啶酸，氨基三唑，硫氰酸铵，四唑磺隆，呋草磺，苄嘧磺隆，噻草平，杀草丹，苯并双环酮，吡草酮，治草醚，双草醚，除草定，溴丁酰草胺，溴苯腈，地乐胺，苯酮唑，长杀草，唑草酯，氯甲丹，氯嘧磺隆，氯苯胺灵，醚磺隆，烯草酮，炔草酯-炔丙基，异噁草酮，播娘蒿胺，二氯吡啶酸，氯酯磺草胺(cloransulam-methyl)，苄草隆，环丙磺隆，噻草酮，氰氟草丁酯，香草隆，麦草畏，敌草腈，精2,4-滴丙酸，唑嘧磺胺，吡氟酰草胺，二氟吡隆，哌草丹，戊草津，二甲吩草胺，精二甲吩草胺，敌草快，氟硫草定，敌草隆，禾草畏，乙氧嘧磺隆，乙氧苯酰草，噁唑禾草灵，乙基噁唑禾草灵，四唑草，啶嘧磺隆，双氟磺草胺，吡氟禾草灵，丁基精吡氟禾草灵，氟吡磺隆，氟噻草胺，氟哒嗪草乙酯，氟唑啶草，氟烯草酸-戊基酯，丙炔氟草胺，伏草隆，氟啶磺隆，氟草烟，氟磺胺草醚，甲酰胺磺隆，fumiclorac，草甘膦，吡氯磺隆，甲基氟吡禾灵，精氟吡禾灵，咪草酯，咪草啶酸，甲咪唑烟酸，灭草烟，灭草喹，咪草烟，啶咪磺隆，茚草酮，碘磺隆，碘苯腈，，异丙隆，异噁酰草胺，异噁氟草酮，乳氟禾草灵，MCPA，MCPB，精2甲4氯丙酸，苯噻酰草胺，甲基二磺隆，甲基磺草酮，噁唑酰草胺，异丙甲草胺，唑草磺胺，甲磺隆，草达灭，单嘧磺隆，MSMA，敌草胺，烟嘧磺隆，达草灭，OK-9701，orthosulfamuron，黄草消，炔丙噁唑草，噁草灵，乙氧氟草醚，百草枯，胺硝草，戊噁唑草，烯草胺，氨氯吡啶酸，氟吡草 胺，哌草磷，冰草胺，氟嘧磺隆，环苯草酮，毒草安，敌稗，异丙草胺，炔苯酰草胺，苄草丹，氟丙磺隆，双唑草腈，氟唑草乙酯，pyrazogyl，吡唑特，吡嘧磺隆，苄草唑，嘧苯草肟，pyrabuticarb，环酯草醚，嘧草醚，pyroxsulam，二氯喹啉酸，灭藻醌，喹禾灵-乙基-D，saflufenacil，稀禾定，西玛津，西草净，s-异丙甲草胺，磺草酮，磺胺草唑，草硫膦，tefuryltrione，tembotrione，特草定，噻醚草胺，噻草啶，禾草丹，绿草定，氟乐灵，抗倒酯和三氟甲磺隆。
与现有技术相比，本发明的有益效果为：
(1)本发明选用草甘膦或草铵膦与双唑草酮混配，对于防除田间杂草具有很好活性，有效减少杂草对田间作物的危害，提高农作物产量，提升品质。
(2)草甘膦或草铵膦与双唑草酮混配，杀草谱具有一定的互补和增效，两者混用有助于降低各成分的用量，降低药害、减少残留活性、延缓除草剂抗药性的发生与发展。
具体实施方式
下面结合实施应用例对本发明进一步说明。
实施应用例1：
草铵膦、草甘膦与双唑草酮混配对杂草的活性测定试验报告。
1试验条件
1.1供试靶标
播娘蒿(Descurainia sophia)、荠菜(Capsella bursa-pastoris)，2015年采自山东省黄岛区试验基地小麦田。
上述杂草采用盆栽法培养。用180*140mm塑料营养钵，摆放于搪瓷盘中，内装从农田采回经风干过筛的表层土壤(4/5处)，土壤湿度初期均控制在20％，挑选籽粒饱满均一的杂草种子，用25℃温水浸泡6小时，在28℃生化培养箱(黑暗)中催芽，将刚刚露白的杂草种子均匀摆放在土壤表面，然后覆土0.7cm。药剂处理后置于可控日光温室内培养，定期在搪瓷盘中加入一定量的水，保持土壤湿润。
1.2培养条件
在可控日光温室内进行，温度18～30℃，自然光照，相对湿度57％～72％。
土壤类型为壤土，有机质含量为1.63％，pH＝7.1，碱解氮84.3mg/kg，速效磷38.5mg/kg，速效钾82.1mg/kg。
1.3仪器设备
3WP-2000型行走式喷雾塔，农业部南京农业机械研究所。GA110型万分之一电子天平(德国)；ZDR2000智能数据记录仪(杭州泽大仪器有限公司)；SPX型智能生化培养箱(宁波江南仪器厂)。
2.试验设计
2.1试剂
2.1.1试验药剂
95％草甘膦(Glyphosate)原药(浙江新安化工集团股份有限公司)；
95％草铵膦(Glufosinate)原药(浙江永农生物科学有限公司提供)；
95％双唑草酮原药(青岛农冠农药有限责任公司提供)。
由于这几种药剂均溶于丙酮，因此，两种原药均采用丙酮作溶剂，用含量0.1％乳化剂T－80水溶液稀释，现用现稀释。
2.2试验处理
2.2.1剂量设置
在确定草铵膦、草甘膦与双唑草酮各组分配比或含量时，应从药剂的作用特点及其毒力等衡量，还要考虑该配方的主要使用目的。草铵膦为灭生性除草剂，通过茎叶吸收后传导到植物各部分。草铵膦与草甘膦杀根不同，草铵膦是内吸很弱，无传导的触杀性除草剂，只在接触部位产生药斑，作用速度快。双唑草酮具有广谱的除草活性，能同时防除阔叶杂草，主要在芽后使用，具有活性高、残留低、环境相容性好、使用安全的特点，防治谱与草甘膦和草铵膦有一定互补。两者混用有助于降低各成分的用量，减少对环境的污染。本研究在前期预试的基础上，设草甘膦、草铵膦、双唑草酮单用及混合用量分别见表1、2，分别共设计15组。以不含药剂、含相同溶剂及乳化剂的水作为空白对照
2.2.2试验重复
每处理重复4次，每次每处理3盆，每盆播种杂草种子20粒，每处理共60株。
2.3处理方式
2.3.1处理时间和次数
试验共用药1次。待杂草2叶1心期，间苗，保持每盆内杂草15株，每处理保留45株，然后继续培养至播娘蒿、荠菜4片真叶期进行处理。
2.3.2使用器械和用药方法
将培养好的试材均匀摆放在面积0.5m2的平台上，用3WP-2000型行走式喷雾塔茎叶喷雾，喷液量按30公斤/公顷计。喷雾压力0.3MPa。待全部药液喷完后，关闭气阀，30秒后，打开喷雾塔门，取出营养钵。然后打开气阀，喷清水50ml，清洗喷液管。
3试验方法
采用盆栽法。杂草培养见1.1，参照《农药室内生物测定试验准则除草剂》进行。用药方法见2.3.2，采用茎叶处理法。
4数据调查与统计分析
4.1调查方法
采用绝对数调查法，用刀片沿土壤表面切断存活杂草整株幼苗，用分析天平称量杂草鲜重。对于已经死亡的杂草，按鲜重为零计。
4.2调查时间和次数
处理后20天调查，共调查1次。
4.3数据统计分析
用Gowing法计算各处理混合组合的理论鲜重抑制率(E0＝X+Y-X*Y/100)，然后与实测抑制率(E)相比较，评价二者混用对杂草的联合作用类型，当E-E0值大于10％为增效作用、小于-10％为拮抗作用、在-10％～10％之间为加成作用。并根据实际防效和除草剂特点、配方的平衡性等因素确定最佳配比。
式中X为草甘膦或草铵膦用量为P时的鲜重抑制率；Y为双唑草酮用量为Q时的鲜重抑制率。统计结果见表1、表2。
5结果分析与讨论
5.1药剂评价
联合作用类型：试验结果表明(表1、表2)，草甘膦或草铵膦与双唑草酮混用各组合处理对2种杂草的抑制率E-E0值≥0，表现出一定的增加药效趋势。
选择制剂的配比范围和含量要适当考虑加工的剂型，若加工成可分散油悬浮剂，制剂的总含量不宜过高，否则黏度太大，难以加工，一般选择相对较小的配比范围。若两药剂加工成可湿性粉剂、水分散性粒剂或水悬浮剂，配比范围可更宽泛。
表1草甘膦、双唑草酮混用对杂草的联合作用效应(Gowing法)
Figure PCTCN2017084916-appb-000002
Figure PCTCN2017084916-appb-000003
药用评价：草甘膦对双唑草酮对播娘蒿、荠菜除草效果测定结果见表1。可见，草甘膦和双唑草酮以675+15、675+30、900+15混配组合物对播娘蒿表现出增效作用，其E-E0值分别对应为20.5、10.7、12.3；对荠菜，675+15、675+30、900+15混配组合表现为增效作用，其E-E0值分别对应21.9、11.6、11.9。其中675+15的混配对播娘蒿、荠菜的增效作用最明显，其E-E0值分别为20.5和21.9。可见，在草甘膦的低剂量和双唑草酮的低剂量组合时表现为很好的增效作用，而在各自的最高剂量时表现为加和作用。草甘膦和双唑草酮的混用在降低用量的情形下也能达到良好防除效果。双唑草酮和草甘膦的配比在1：20-60附近增效更为明显。
表2草铵膦、双唑草酮混用对杂草的联合作用效应(Gowing法)
Figure PCTCN2017084916-appb-000004
Figure PCTCN2017084916-appb-000005
药用评价：草铵膦对双唑草酮对播娘蒿、荠菜除草效果测定结果见表2。可见，草铵膦和双唑草酮以300+15、300+30、450+15混配组合物对播娘蒿表现出增效作用，其E-E0值分别对应为23.4、12.9、13.3；对荠菜，300+15、300+30、450+15混配组合表现为增效作用，其E-E0值分别对应23.8、14.3、12.3。其中300+15的混配对播娘蒿、荠菜的增效作用最明显，其E-E0值分别为23.4和23.8。可见，在草铵膦的低剂量和双唑草酮的低剂量组合时表现为很好的增效作用，而在各自的最高剂量时表现为加和作用。草铵膦和双唑草酮的混用在降低用量的情形下也能达到良好防除效果。双唑草酮和草铵膦的配比在1：20-30附近增效更为明显。
实施应用例2：
为了更好地理解本发明，以下结合实施例具体说明本发明的技术内容，下列实施例中的百分比均为质量百分比。
实施例1 水悬浮剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：1％双唑草酮+30％草甘膦+12％EO-PO嵌段聚醚+2％萘磺酸盐类润湿剂+0.2％黄原胶+5％丙三醇+水补足。
上述水悬浮剂加工设备：混料釜、胶体磨、砂磨机、剪切机等。
上述水悬浮剂加工过程：将所有物料投入混料釜中，搅拌混合后过胶体磨，之后进入砂磨机三级砂磨，最后在剪切机中剪切均匀，化验合格后，转移至储罐灌装。
实施例2 水悬浮剂
化合物环吡氟草酮，当活性成分B为草铵膦。
配方组成为：2％双唑草酮+20％草铵膦+5％苯乙基酚聚氧乙烯醚磷酸酯三乙醇胺盐+2％脂肪醇聚氧乙烯醚+0.15％黄原胶+5％丙三醇+水补足。
上述水悬浮剂加工设备：混料釜、胶体磨、砂磨机、剪切机等。
上述水悬浮剂加工过程：将所有物料投入混料釜中，搅拌混合后过胶体磨，之后进入砂磨机三级砂磨，最后在剪切机中剪切均匀，化验合格后，转移至储罐灌装。
表3水悬浮剂主要技术指标
Figure PCTCN2017084916-appb-000006
实施例3 可分散油悬浮剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：1％双唑草酮+20％草甘膦+2％十二烷基苯磺酸钙+4％苯乙基苯酚聚氧乙烯醚磷酸酯三乙醇胺盐+5％脂肪醇聚氧乙烯醚+4％蓖麻油聚氧乙烯醚+2.2％有机膨润土+油酸甲酯补足。
上述可分散油悬浮剂加工设备：混料釜、胶体磨、砂磨机、剪切机等。
上述可分散油悬浮剂加工过程：将所有物料投入混料釜中，搅拌混合后过胶体磨，之后进入砂磨机三级砂磨，最后在剪切机中剪切均匀，化验合格后，转移至储罐灌装。
实施例4 可分散油悬浮剂
化合物双唑草酮，当活性成分B为草铵膦。
配方组成为：1％双唑草酮+20％草铵膦+4％顺丁烯二仲辛酯磺酸钠+6％壬基酚聚氧乙烯醚+7％蓖麻油聚氧乙烯醚+2％有机膨润土+10％豆油+油酸甲酯补足。
上述可分散油悬浮剂加工设备：混料釜、胶体磨、砂磨机、剪切机等。
上述可分散油悬浮剂加工过程：将所有物料投入混料釜中，搅拌混合后过胶体磨，之后进入砂磨机三级砂磨，最后在剪切机中剪切均匀，化验合格后，转移至储罐灌装。
表4可分散油悬浮剂主要技术指标
Figure PCTCN2017084916-appb-000007
实施例5 可湿性粉剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：2％双唑草酮+60％草甘膦+10％萘磺酸盐类分散剂+5％拉开粉+5％沉淀法白炭黑+高岭土补足。
上述可湿性粉剂加工设备：机械粉碎机、气流粉碎机。
上述可湿性粉剂加工过程：将原药、助剂、填料等投入机械粉碎机中，之后过气流粉碎机，取样化验合格后备用。
实施例6 可湿性粉剂
化合物双唑草酮，当活性成分B为草铵膦。
配方组成为：3％双唑草酮+40％草铵膦+10％木质素磺酸钠类分散剂+2.5％十二烷基硫酸钠+10％沉淀法白炭黑+钙基膨润土补足
上述可湿性粉剂加工设备：机械粉碎机、气流粉碎机。
上述可湿性粉剂加工过程：将原药、助剂、填料等投入机械粉碎机中，之后过气流粉碎机，取样化验合格后备用。
表5可湿性粉剂主要技术指标
Figure PCTCN2017084916-appb-000008
实施例7 可溶性粉剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：2％双唑草酮+60％草甘膦+20％EO-PO嵌段聚醚分散剂+5％拉开粉+5％尿素+硫酸铵补足
上述可溶性粉剂加工设备：机械粉碎机、气流粉碎机。
上述可溶性粉剂加工过程：将原药、助剂、填料等投入机械粉碎机中，之后过气流粉碎机，取样化验合格后备用。
实施例8 可溶性粉剂
化合物双唑草酮，当活性成分B为草铵膦。
配方组成为：2％双唑草酮+20％草铵膦+20％萘磺酸盐类分散剂+5％十二烷基硫酸钠+1％沉淀法白炭黑+无水硫酸钠补足
上述可溶性粉剂加工设备：机械粉碎机，气流粉碎机。
上述可溶性粉剂加工过程：将原药、助剂、填料等投入机械粉碎机中，之后过气流粉碎 机，取样化验合格后备用。
表6可溶性粉剂主要技术指标
Figure PCTCN2017084916-appb-000009
实施例9 水分散粒剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：2％双唑草酮+60％草甘膦+10％聚羧酸盐类分散剂+5％拉开粉+1％崩解剂聚乙烯醇+填料硅藻土补足。
上述水分散粒剂加工设备：气流粉碎机，犁刀式混合机，篮式造粒机，干燥箱，筛分机等。
上述水分散粒剂加工过程：将上述物料混合均匀过气流粉碎，加水入捏合造粒，之后干燥，最后筛分得到成品。
实施例10 水分散粒剂
化合物双唑草酮，当活性成分B为草铵膦。
配方组成为：2％双唑草酮+20％草铵膦+15％萘磺酸盐类分散剂+2.5％十二烷基苯磺酸钠+1％崩解剂聚乙二醇-4000+填料高岭土补足。
上述水分散粒剂加工设备：气流粉碎机，犁刀式混合机，篮式造粒机，干燥箱，筛分机等。
上述水分散粒剂加工过程：将上述物料混合均匀过气流粉碎，加水入捏合造粒，之后干燥，最后筛分得到成品。
表7水分散粒剂主要技术指标
Figure PCTCN2017084916-appb-000010
实施例11 可溶性粒剂
化合物双唑草酮，当活性成分B为草甘膦。
配方组成为：2％双唑草酮+60％草甘膦+12％聚羧酸盐类分散剂+5％拉开粉+1％崩解剂聚乙烯醇+填料尿素补足。
上述可溶性粒剂加工设备：气流粉碎机，犁刀式混合机，篮式造粒机，干燥箱，筛分机等。
上述可溶性粒剂加工过程：将上述物料混合均匀过气流粉碎，加水入捏合造粒，之后干燥，最后筛分得到成品。
实施例12 可溶性粒剂
化合物双唑草酮，当活性成分B为草铵膦。
配方组成为：2％双唑草酮+40％草铵膦+15％萘磺酸盐类分散剂+2.5％十二烷基苯磺酸钠+1％崩解剂聚乙二醇-4000+填料无水硫酸钠补足。
上述可溶性粒剂加工设备：气流粉碎机，犁刀式混合机，篮式造粒机，干燥箱，筛分机等。
上述可溶性粒剂加工过程：将上述物料混合均匀过气流粉碎，加水入捏合造粒，之后干燥，最后筛分得到成品。
表8可溶性粒剂主要技术指标
Figure PCTCN2017084916-appb-000011
实施应用例3：
草甘膦、草铵膦与双唑草酮复配组合物防治非耕地杂草田间药效试验
防治药剂：草甘膦、草铵膦与双唑草酮复配组合物，由青岛农冠农药有限责任公司研发生产。
对照药剂：30％草甘膦水剂；200g/L草甘膦可溶性液剂(市购)；10％双唑草酮OD(青岛农冠农药有限责任公司)。
设人工除草和清水对照处理。
使用方法：每亩兑水30升后均匀喷雾于各小区内。
施药时间：杂草旺盛生长期，进行茎叶喷雾1次。
调查方法及药效计算：
调查杂草对象为：播娘蒿、荠菜、反枝苋、马齿苋等杂草，调查施药后20天、40天对杂草的鲜重防效。
按下列公式计算鲜重防效。
Figure PCTCN2017084916-appb-000012
表9草甘膦·双唑草酮复配组合物防治非耕地杂草药效试验
Figure PCTCN2017084916-appb-000013
上述表9中仅详细列出播娘蒿和荠菜的具体数据，其中总体表示播娘蒿、荠菜、反枝苋、马齿苋等杂草的统计平均值；由表9可知草甘膦、双唑草酮复配对非耕地的杂草有很好的防治效果，防效优于单剂防效，与对照药剂、相对于清水对照处理的之间差异显著，并且具有较好的速效性和持效性。
表10草铵膦·双唑草酮复配组合物防治非耕地杂草药效试验
Figure PCTCN2017084916-appb-000014
上述表10中仅详细列出播娘蒿和荠菜的具体数据，其中总体表示马唐、播娘蒿、荠菜、反枝苋、马齿苋等杂草的统计平均值；由表10可知，草铵膦与双唑草酮复配对非耕地的杂草有很好的防治效果，防效优于单剂防效，与对照药剂、人工除草、相对于清水对照处理的之间差异显著，并且具有较好的速效性及持效性。

Claims (8)

  1. 一种含有双唑草酮的复配除草组合物，其特征在于，包括活性成分A和B，所述的活性成分A为双唑草酮，活性成分B为草甘膦或草铵膦。
  2. 根据权利要求1所述含有双唑草酮的复配除草组合物，其特征在于，活性成分A与活性成分B重量配比为1:100-1。
  3. 根据权利要求2所述含有双唑草酮的复配除草组合物，其特征在于，活性成分A与活性成分B重量配比为1:60-1。
  4. 根据权利要求1或2所述含有双唑草酮的复配除草组合物，其特征在于，所述活性成分的浓度为0.001-98wt％。
  5. 根据权利要求4所述含有双唑草酮的复配除草组合物，其特征在于，所述活性成分的浓度为0.01-90wt％。
  6. 根据权利要求1或2所述含有双唑草酮的复配除草组合物，其特征在于，所述复配除草组合物还包括助剂，所述的助剂选自液体载体、固体载体、分散剂、乳化剂、稳定剂、防冻剂和增稠剂中的至少一种。
  7. 根据权利要求1或2所述含有双唑草酮的复配除草组合物，其特征在于，所述复配除草组合物的剂型为液剂、可湿性粉剂、可溶性粉剂、可溶性粒剂、乳油、水悬浮剂、可分散油悬浮剂、微囊剂、微乳剂、水乳剂、悬浮乳剂、水分散粒剂、胶囊水悬混剂、超低容量液剂或种衣剂。
  8. 一种防治不希望有的植物的方法，其特征在于，将权利要求1-7任意一项所述含有双唑草酮的复配除草组合物施用于不希望有的植物的生长场所和/或叶和/或茎上。
PCT/CN2017/084916 2016-06-21 2017-05-18 含有双唑草酮的复配除草组合物及其使用方法 WO2017219805A1 (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA3029080A CA3029080C (en) 2016-06-21 2017-05-18 Herbicidal composition containing shuangzuocaotong and a method of usingthe same
US16/312,770 US20190216089A1 (en) 2016-06-21 2017-05-18 Compounded herbicidal composition containing shuangzuocaotong and method of using the same
AU2017280298A AU2017280298B2 (en) 2016-06-21 2017-05-18 Compounded herbicidal composition containing Shuangzuocaotong and method of using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610452583.0A CN106070309B (zh) 2016-06-21 2016-06-21 含有双唑草酮的复配除草组合物及其使用方法
CN201610452583.0 2016-06-21

Publications (1)

Publication Number Publication Date
WO2017219805A1 true WO2017219805A1 (zh) 2017-12-28

Family

ID=57237830

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/084916 WO2017219805A1 (zh) 2016-06-21 2017-05-18 含有双唑草酮的复配除草组合物及其使用方法

Country Status (5)

Country Link
US (1) US20190216089A1 (zh)
CN (1) CN106070309B (zh)
AU (1) AU2017280298B2 (zh)
CA (1) CA3029080C (zh)
WO (1) WO2017219805A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106070309B (zh) * 2016-06-21 2018-06-15 江苏清原农冠抗性杂草防治有限公司 含有双唑草酮的复配除草组合物及其使用方法
CN106946784B (zh) * 2017-05-02 2019-02-12 青岛清原化合物有限公司 无定形态双唑草酮及其制备方法和用途
CN107286096B (zh) * 2017-07-13 2019-05-03 青岛清原化合物有限公司 双唑草酮e晶型及其制备方法和用途
CN107286095B (zh) * 2017-07-13 2019-05-03 青岛清原化合物有限公司 双唑草酮d晶型及其制备方法和用途
CN107311930B (zh) * 2017-07-13 2019-05-03 青岛清原化合物有限公司 双唑草酮b晶型及其制备方法和用途
CN107646848A (zh) * 2017-11-09 2018-02-02 青岛清原化合物有限公司 一种含双唑草酮的除草组合物及其应用
CN108535369B (zh) * 2018-03-14 2021-03-12 山东省农业科学院植物保护研究所 一种检测小麦种植中双唑草酮残留量的方法
CN111896654B (zh) * 2020-08-05 2022-12-20 安徽华辰检测技术研究院有限公司 生姜中乙草胺及其代谢物ema、hema的分析方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101541755A (zh) * 2006-11-28 2009-09-23 石原产业株式会社 苯甲酰吡唑化合物及其生产方法和含有它们的除草剂
CN102986705A (zh) * 2012-11-30 2013-03-27 王学权 一种含有苯唑草酮的除草剂组合
CN103980202A (zh) * 2014-05-27 2014-08-13 青岛清原化合物有限公司 一种具有除草活性的4-苯甲酰吡唑类化合物
CN105230629A (zh) * 2015-11-17 2016-01-13 青岛清原抗性杂草防治有限公司 增效除草组合物
CN105503728A (zh) * 2015-12-31 2016-04-20 青岛清原化合物有限公司 吡唑类化合物或其盐、制备方法、除草剂组合物及用途
CN106070309A (zh) * 2016-06-21 2016-11-09 青岛清原抗性杂草防治有限公司 含有双唑草酮的复配除草组合物及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939559A (en) * 1995-02-07 1999-08-17 Nissan Chemical Industries, Ltd. Pyrazole derivative and herbicidal composition
MXPA02009567A (es) * 2000-03-31 2004-05-14 Bayer Cropscience Gmbh Benzoilpirzoles y su uso como herbicidas.
DE10157339A1 (de) * 2001-11-22 2003-06-12 Bayer Cropscience Gmbh Synergistische herbizide Mittel enthaltend Herbizide aus der Gruppe der Benzoylpyrazole

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101541755A (zh) * 2006-11-28 2009-09-23 石原产业株式会社 苯甲酰吡唑化合物及其生产方法和含有它们的除草剂
CN102986705A (zh) * 2012-11-30 2013-03-27 王学权 一种含有苯唑草酮的除草剂组合
CN103980202A (zh) * 2014-05-27 2014-08-13 青岛清原化合物有限公司 一种具有除草活性的4-苯甲酰吡唑类化合物
CN105230629A (zh) * 2015-11-17 2016-01-13 青岛清原抗性杂草防治有限公司 增效除草组合物
CN105503728A (zh) * 2015-12-31 2016-04-20 青岛清原化合物有限公司 吡唑类化合物或其盐、制备方法、除草剂组合物及用途
CN106070309A (zh) * 2016-06-21 2016-11-09 青岛清原抗性杂草防治有限公司 含有双唑草酮的复配除草组合物及其使用方法

Also Published As

Publication number Publication date
CN106070309A (zh) 2016-11-09
CN106070309B (zh) 2018-06-15
CA3029080C (en) 2023-08-29
CA3029080A1 (en) 2017-12-28
AU2017280298A1 (en) 2019-01-31
AU2017280298B2 (en) 2021-02-25
US20190216089A1 (en) 2019-07-18

Similar Documents

Publication Publication Date Title
WO2017219805A1 (zh) 含有双唑草酮的复配除草组合物及其使用方法
WO2017219804A1 (zh) 含有环吡氟草酮的复配除草组合物及其使用方法
CN103181391A (zh) 含有苯唑草酮和莠去津的除草剂组合物
CN103783076B (zh) 一种含草甘膦、双草醚和二甲四氯的混合除草剂及其应用
CN105409961A (zh) 一种含氟啶胺的杀菌组合物及其应用
CN101911947A (zh) 一种小麦田除草剂组合物
CN101911948B (zh) 一种含醚磺隆的除草剂组合物
CN103828816A (zh) 含精噁唑禾草灵、炔草酯和氯氟吡氧乙酸的混合除草剂
CN106376576A (zh) 一种三元除草组合物
CN107509733A (zh) 一种含有莠去津和砜吡草唑的玉米田除草组合物
CN103190414A (zh) 含有苯唑草酮和二甲四氯的除草剂组合物
CN108013051A (zh) 一种含氟磺胺草醚和砜吡草唑的除草剂组合物
CN104872162A (zh) 一种含苯唑草酮的玉米田除草组合物
CN107347907A (zh) 一种含草甘膦的三元除草组合物
CN107372589A (zh) 一种含草甘膦的三元除草组合物
WO2018076667A1 (zh) 一种小麦田除草组合物及其应用
CN106665628A (zh) 含吡嘧磺隆、丙草胺、苯噻酰草胺的除草剂及其应用
CN103651479B (zh) 一种含有单嘧磺隆和杀草胺的除草组合物
CN113100244B (zh) 一种除草剂组合物及其应用
CN115104622B (zh) 一种精草铵膦与苯唑草酮的复配组合物
CN105724384A (zh) 一种含氟吡菌胺的杀菌组合物及其应用
CN105409978A (zh) 一种农药组合物、除草剂及应用
CN111758737A (zh) 一种包含唑嘧磺草胺和精喹禾灵的除草组合物
CN105410004B (zh) 一种含五氟磺草胺与唑草胺的除草剂组合物
CN106172453A (zh) 一种杀菌组合物及其应用

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17814543

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 3029080

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2017280298

Country of ref document: AU

Date of ref document: 20170518

Kind code of ref document: A

122 Ep: pct application non-entry in european phase

Ref document number: 17814543

Country of ref document: EP

Kind code of ref document: A1