WO2017179345A1 - Injector - Google Patents

Abstract

An injector 100 is provided with: a first drive section 2 for pushing a first medical liquid out of a first syringe 91 filled with the first medical liquid; a closure section 16 for closing a flow passage within a tube 103 connected to the first syringe 91; and a stirring unit 3 for rocking the first syringe 91 while the closure section 16 closes the flow passage.

Description

Injection device

The present invention relates to an injection device for injecting a chemical solution, and relates to an injection device capable of stirring the chemical solution in a syringe to be mounted.

There is a contrast medium made of a suspension as a chemical solution used for imaging by a medical imaging apparatus, for example, an ultrasonic diagnostic apparatus. This contrast agent contains microbubbles or solid particles to scatter ultrasonic waves. When performing an ultrasonic diagnosis, a syringe filled with the contrast medium is mounted on the injection device, and imaging is performed after the contrast medium is injected into the body of the subject. The ultrasonic diagnostic apparatus captures an image of the inside of a body by analyzing ultrasonic waves that are incident on and reflected by microbubbles or solid particles. Here, separation may occur in the contrast agent after the syringe is mounted on the injection device, and the concentration of the content of the contrast agent may be biased.

Patent Document 1 discloses an injection apparatus including a holding unit that holds a syringe filled with a contrast agent, and a stirring unit that is connected to the holding unit and swings the holding unit. A three-way cock is connected to the syringe held by the holding unit, and the injection device includes an installation portion for the three-way cock. Further, the injection device includes a lever driving unit that drives a switching lever of the three-way cock, and does not push out the contrast agent when the contrast agent channel is not opened.

International Publication No. 2015/141202

In the injection device disclosed in Patent Document 1, a space for driving with a three-way cock is required. This increases the size of the injection device.

In order to solve the above problems, an injection device according to the present invention includes a first drive unit that pushes out the first chemical solution from a first syringe filled with the first chemical solution, and a flow in a tube connected to the first syringe. It is characterized by comprising: a closing part for closing a passage; and a stirring unit for swinging the first syringe in a state where the closing part opens the flow path.

This makes it possible to reduce the size of the injection device while preventing the destruction of the microbubbles.

Further features of the present invention will become apparent from the following description of embodiments, given by way of example with reference to the accompanying drawings.

It is a schematic perspective view of an injection device. It is a schematic perspective view which shows the inside of an injection device. It is a schematic perspective view which shows a stirring unit. It is a schematic perspective view which shows a transmission mechanism. It is a schematic perspective view which shows a closing part. It is the schematic which shows an open state. It is the schematic which shows a closed state. It is a schematic block diagram of an injection device. It is a flowchart of channel closing. It is a schematic perspective view of a 2nd drive part. It is a schematic sectional drawing of a 2nd drive part. It is a flow chart of channel closure concerning a 2nd embodiment of the present invention. It is a schematic block diagram of the injection apparatus which concerns on 3rd Embodiment of this invention. It is a flowchart of the automatic rocking | fluctuation mode which concerns on 3rd Embodiment.

Hereinafter, exemplary embodiments for carrying out the present invention will be described in detail with reference to the drawings. However, dimensions, materials, shapes, and relative positions of components described in the following embodiments are arbitrary, and can be changed according to the configuration of the apparatus to which the present invention is applied or various conditions. In addition, unless otherwise specified, the scope of the present invention is not limited to the embodiments specifically described below. In the present specification, “up and down” corresponds to an upward direction and a downward direction in the direction of gravity, respectively. Moreover, let the side in which the syringe in an injection head is mounted be a front side, and let the opposite side of the front side be a rear side.

[First Embodiment]
FIG. 1 is a schematic perspective view of an injection device (injector) 100 that is used when a body of a subject is imaged by a medical imaging apparatus, for example, an ultrasonic diagnostic apparatus. As shown in FIG. 1, an injection device 100 for injecting a chemical solution includes an injection head 1 on which a first syringe 91 and a second syringe 92 are mounted. In addition, the injection device 100 includes a holding member 11 that holds the first syringe 91. The holding member 11 is formed by aluminum die casting, but can also be formed by resin. FIG. 1 shows a state in which the presser 21 advances the piston 914 of the first syringe 91 to the limit position, and the presser 61 advances the piston 924 of the second syringe 92 to the limit position.

The injection device 100 includes a holding unit 12 that holds the second syringe 92, and the holding unit 12 is provided on the front frame 15 of the injection head 1. The injection head 1 is provided with a display unit 13 and an operation unit 14. The display unit 13 displays the elapsed time from the start of injection, the injection amount, the injection speed, and the like. The injection head 1 can also display such information on a portable display or a tablet computer. These devices are wirelessly connected to the injection head 1 according to a standard such as Bluetooth (registered trademark) or Wi-Fi, and can be replaced with the display unit 13 and the operation unit 14 of the injection head 1. Furthermore, instead of the display unit 13 and the operation unit 14, a touch panel may be provided on the injection head 1.

The first syringe 91 is filled with a contrast agent which is a suspension as a first chemical solution. The second syringe 92 is filled with physiological saline as the second chemical solution. These chemical solutions may be manually filled into the first syringe 91 or the second syringe 92, or may be filled into the first syringe 91 or the second syringe 92 with the injection device 100 or the filling device. Further, the first syringe 91 and the second syringe 92 may be prefilled syringes.

The first tube 103 is connected to the tip of the first syringe 91. Further, a guide portion 106 for guiding the first tube 103 is formed in the front frame 15 of the injection head 1. This guide part 106 consists of a substantially U-shaped groove | channel, and the 1st tube 103 is mounted in the said groove | channel.

The second tube 104 is connected to the tip of the second syringe 92. The second tube 104 is connected to the first tube 103 via a T-shaped connector. Furthermore, the third tube 105 is connected to the first syringe 91 via the first tube 103. The distal end of the third tube 105 is connected to a catheter or the like. The T-shaped connector can be replaced with a connector having another shape such as a Y-shape, or a mixing device (for example, “SPIRAL FLOW” (registered trademark) manufactured by Nemoto Kyorindo Co., Ltd.).

In addition, a foot switch and a hand switch (not shown) can be connected to the injection apparatus 100 by wire. The operator can start the injection of the chemical liquid by operating the foot switch and the hand switch. Note that the foot switch and the hand switch may be wirelessly connected to the injection head 1. Further, instead of the foot switch and the hand switch, another remote control device can be connected to the injection head 1 by wire or wirelessly.

The injection head 1 is connected to an external power source via an AC adapter (not shown). However, the injection head 1 can also incorporate a battery. Moreover, the injection head 1 may be mounted on a caster stand (not shown) or may be configured integrally with the caster stand. Furthermore, a ceiling suspension member can be provided, and the injection head 1 can be suspended from the ceiling via the ceiling suspension member.

FIG. 2 shows the inside of the injection head 1 with the upper frame and the lower frame removed. As shown in FIG. 2, the injection device 100 includes a first drive unit 2 that pushes out the first chemical solution from the first syringe 91 filled with the contrast agent that is the first chemical solution, and the first chemical solution in the first syringe 91. In order to stir, a stirring unit 3 that swings the first syringe 91 via the holding member 11 is provided. The injection device 100 includes a second drive unit 6 that pushes out the second chemical solution from the second syringe 92 filled with the second chemical solution. And the 1st drive part 2, the 2nd drive part 6, and the stirring unit 3 are accommodated in both flame | frames of the injection | pouring head 1. FIG.

The first drive unit 2 presses the rear end of the mounted first syringe 91 (the rear end of the piston 914) to press the contrast agent from the first syringe 91, and the actuator that moves the presser 21 forward or backward 22. The actuator 22 includes a feed screw nut, a feed screw shaft, a motor, a transmission mechanism that transmits rotation from the motor to the feed screw shaft, and a forward and backward rod (both not shown). Further, the first drive unit 2 has a presser pipe 23 connected to the rod of the actuator 22.

The presser 21 is fixed to the presser pipe 23. When the motor of the actuator 22 rotates forward with the presser 21 in contact with the rear end of the piston 914, the presser 21 pushes the piston 914 forward. As a result, when the piston 914 moves forward, the contrast medium in the first syringe 91 is pushed out, and the subject's subject is connected via the first tube 103, the T-shaped connector and the third tube 105 connected to the tip of the first syringe 91. Injected into the body. On the other hand, when the motor reverses, the presser 21 can move backward and return to the original position.

The second drive unit 6 also has a presser 61 and an actuator 62. The actuator 62 has the same structure as the actuator 22. On the other hand, the presser 61 has a syringe hook 611 for fixing the rear end of the piston 924 to the presser 61. Then, when the presser 61 moves backward in a state where the rear end of the piston 924 is fixed to the presser 61, the piston 924 can be moved backward.

The presser 61 is fixed to the presser pipe 63. Then, when the motor of the actuator 62 rotates forward with the presser 61 in contact with the rear end of the piston 924, the presser 61 pushes the piston 924 forward. Thus, when the piston 924 advances, the physiological saline in the second syringe 92 is pushed out, and the subject is connected via the second tube 104, the T-shaped connector, and the third tube 105 connected to the tip of the second syringe 92. Injected into the body. On the other hand, when the motor rotates in the reverse direction, the presser 61 can move backward and the piston 924 can move backward. The presser 21 and the presser 61 are both made of aluminum, but can be made of resin.

A groove portion 111 having a substantially U-shaped cross section for holding the body portion of the first syringe 91 is attached to the front end portion of the holding member 11 that holds the first syringe 91. Further, the holding member 11 has a flange groove portion 112 adjacent to the groove portion 111, and the flange of the first syringe 91 is inserted into the flange groove portion 112. Thereby, the holding member 11 holds the first syringe 91, and when the stirring unit 3 swings the holding member 11, the first syringe 91 swings together with the holding member 11. The holding portion 12 that holds the second syringe 92 is provided with a flange groove portion 122 into which the flange of the second syringe 92 is inserted. Thereby, the holding unit 12 holds the second syringe 92.

[Stirring unit]
Next, the stirring unit 3 that swings the first syringe 91 will be described with reference to FIGS. 3 and 4. 3 shows the stirring unit 3 viewed from the upper rear side, and FIG. 4 shows the transmission mechanism 33 viewed from the front side.

As shown in FIG. 3, the stirring unit 3 includes a stirring motor 32 that drives the holding member 11 and a transmission mechanism 33 that transmits the rotational force from the stirring motor 32 to the holding member 11. As the stirring motor 32, a DC motor can be used. In addition, the stirring unit 3 includes a swing detection unit 35 that detects the swing angle of the holding member 11. The swing detection unit 35 is, for example, an optical slit sensor.

The transmission mechanism 33 includes a rotating member 124 (FIG. 4) that is rotatably attached to the fixed portion 134 via a needle bearing. The holding member 11 is fixed to the rotating member 124 via a washer. The transmission mechanism 33 includes a pulley 331 that rotates together with the output shaft of the stirring motor 32, a belt 332 that is wound around the pulley 331, and a pulley 333 that is wound around the belt 332 and connected to the rotating member 124. Have. The pulley 333 is fixed to the rotating member 124 with a screw through a washer. The transmission mechanism 33 may have a gear instead of the pulley 331 and the belt 332.

Further, a shield plate 34 having a slit of a predetermined angle is fixed to the pulley 333 of the transmission mechanism 33 with a screw. Then, the swing detection unit 35 detects the slit of the shielding plate 34 and detects that the holding member 11 swings by a predetermined angle. That is, the shielding plate 34 is fixed to the pulley 333 by screws, and the shielding plate 34 rotates together with the pulley 333 and the rotating member 124. Then, the swing detection unit 35 detects the swing angle of the holding member 11 by detecting the slit of the shielding plate 34.

The swing detection unit 35 and the shielding plate 34 may be configured to detect the origin that is the original position when swinging. In this case, the swing detection unit 35 detects the origin of the swing of the holding member 11 by detecting the slit of the shielding plate 34. The swing angle is detected by the encoder 321 of the stirring motor 32.

As shown in FIG. 4, the transmission member 114 is fixed to the front surface of the rotating member 124 with screws. A fitting groove into which the transmission member 114 is fitted is formed at the rear end of the holding member 11. The transmission member 114 has an external shape complementary to the internal shape of the fitting groove of the holding member 11. A hole through which the presser pipe 23 passes is formed at the center of the transmission member 114, and the transmission member 114 has a pair of protrusions 115 protruding on both sides of the hole.

The transmission member 114 is fixed to the rear surface of the holding member 11 by two screws 116 that are fitted in the fitting grooves of the holding member 11 and penetrate the protruding portion 115. As a result, when the pulley 333 rotates, the holding member 11 rotates via the rotating member 124 and the transmission member 114. Similar to the transmission member 114, a hole through which the presser pipe 23 passes is formed at the center of the shielding plate 34, the pulley 333, and the rotating member 124.

[Closed part]
The injection device 100 includes a closing portion 16 that closes the flow path in the first tube 103 connected to the first syringe 91. The closing portion 16 is provided on the guide portion 106 (FIG. 1) of the first tube 103. Hereinafter, the closing part 16 will be described with reference to FIG. FIG. 5 is a schematic perspective view of the closing portion 16 as viewed from the front.

As shown in FIG. 5, the closing part 16 includes an actuator 161, a clamp member 162 driven by the actuator 161, and a closing detection part 169 that detects closing of the flow path in the first tube 103. The actuator 161 has the same structure as the actuator 22 of the first drive unit 2 or the actuator 62 of the second drive unit 6. The actuator 161 has a rod 168 (FIG. 7) that can move in the vertical direction.

The clamp member 162 has a substantially U-shaped protrusion 1621 that protrudes toward the rod 168 of the actuator 161. And the protrusion part 1621 is rotatably connected with respect to the rod 168 via the rod axis | shaft 164 so that the front-end | tip of the rod 168 may be located inside the protrusion part 1621. FIG. The clamp member 162 has a shaft hole portion 1622. The clamp member 162 is rotatably connected to the guide portion 106 of the first tube 103 via a clamp shaft 165 inserted into the shaft hole portion 1622.

The closing detection unit 169 is, for example, an optical slit sensor. Further, a shielding member 163 protruding downward is fixed to the clamp member 162 with a screw. The closure detection unit 169 detects that the clamp member 162 has closed the flow path in the first tube 103 by detecting that the shield member 163 has shielded it.

A shaft hole is formed at the lower end of the case of the actuator 161. The actuator 161 is rotatably connected to the front frame 15 via a case shaft 166 inserted into the shaft hole.

Subsequently, the operation of the clamp member 162 will be described with reference to FIGS. 6 is a schematic plan view showing the clamp member 162 in the open state as viewed from the rear, and FIG. 7 is a schematic plan view showing the clamp member 162 in the closed state as viewed from the rear.

6, the flow path in the first tube 103 inserted into the guide portion 106 is open. At this time, except for the tip of the rod 168, the rod 168 (FIG. 7) is accommodated in the case of the actuator 161. That is, the rod 168 is in the lowered position that is completely lowered. The clamp member 162 connected to the rod 168 via the rod shaft 164 is in an open position separated from the first tube 103.

When closing the first tube 103, the actuator 161 raises the rod 168 to the raised position shown in FIG. When the rod 168 rises, the protrusion 1621 rises through the rod shaft 164. Therefore, the clamp member 162 rotates around the clamp shaft 165. As a result, the clamp member 162 protrudes into the guide portion 106 and crushes the first tube 103 in the guide portion 106. As a result, the contrast member flow path in the first tube 103 is closed by the clamp member 162.

When the clamp member 162 rotates, the shielding member 163 fixed to the clamp member 162 also rotates toward the closure detection unit 169 about the clamp shaft 165. Accordingly, the closing detection unit 169 detects that the first tube 103 is closed by being shielded by the shielding member 163. When the rod 168 is raised, the actuator 161 is slightly rotated around the case shaft 166 toward the clamp shaft 165.

When opening the closed first tube 103, the actuator 161 lowers the rod 168 to the lowered position shown in FIG. When the rod 168 is lowered, the protruding portion 1621 is lowered via the rod shaft 164. Therefore, the clamp member 162 rotates around the clamp shaft 165. As a result, the clamp member 162 is retracted from the guide portion 106, and the first tube 103 in the guide portion 106 returns to its original shape. As a result, the contrast agent flow path in the first tube 103 is opened.

Further, when the clamp member 162 rotates, the shielding member 163 also rotates in the direction away from the closure detection unit 169 about the clamp shaft 165. Thereby, shielding by the shielding member 163 is released. When the rod 168 is lowered, the actuator 161 is slightly rotated around the case shaft 166 in a direction away from the clamp shaft 165.

[Flow path closing flow]
When the first syringe 91 swings in a state where the closing portion 16 is squeezing the first tube 103, the first tube 103 is twisted. Therefore, the stirring unit 3 of the injection device 100 swings the first syringe 91 in a state where the closing portion 16 opens the flow path in the first tube 103. In other words, the closing part 16 of the injection device 100 opens the flow path in the first tube 103 before the stirring unit 3 swings the first syringe 91.

Also, if the piston 924 of the second syringe 92 is pushed with the contrast medium flow path open, the contrast medium is pressurized, resulting in breakage of microbubbles in the suspension. Therefore, the closing part 16 closes the flow path in the first tube 103 when the second chemical liquid is pushed out from the second syringe 92.

The closing of the flow path will be described with reference to the schematic block diagram of FIG. 8 and the flowchart of FIG. As shown in FIG. 8, the injection device 100 includes a control unit 5 that controls the first drive unit 2, the second drive unit 6, the stirring unit 3, and the closing unit 16, and a memory unit 53 as a storage unit. Yes. Moreover, the control part 5 has the chemical | medical solution judgment part 51 which judges the chemical | medical solution to inject | pour, the warning alerting | reporting part 52 which alert | reports an error, and the completion | finish judgment part 54 which judges the completion | finish of extrusion of a 2nd chemical | medical solution.

The control unit 5 is, for example, a CPU that is a one-chip microcomputer, and is disposed below the first drive unit 2, the second drive unit 6, and the stirring unit 3. And the control part 5 performs the process operation | movement of the injection apparatus 100 whole, such as predetermined | prescribed calculation, control, and discrimination | determination besides control of each motor according to the program memorize | stored in the memory part 53 previously. The memory unit 53 includes a RAM (Random Access Memory) which is a system work memory for operating a main CPU (Central Processing Unit), a ROM (Read Only Memory) storing a program or system software, a hard disk drive, or the like. .

The injection of the first chemical solution and the second chemical solution is automatically performed according to the injection protocol. In this injection protocol, for example, an injection time, an injection speed, an injection amount, and an injection pressure limit value are set. Then, the display unit 13 displays the contents of the injection protocol such as the injection speed, and the operator can check the contents of the injection protocol.

The injection protocol, drug solution data, and the like are stored in the memory unit 53 in advance. When injecting a chemical into a subject, the operator can input data such as an injection speed and an injection amount into the control unit 5 by operating the input key 141 (FIG. 1) of the operation unit 14. The operator may input data such as the injection time, the maximum injection pressure, and the tube type in addition to the above data via an input device provided separately. The operator can also read the injection protocol and various data from an external storage medium. Furthermore, the control unit 5 may calculate the injection conditions based on the input data and data stored in advance, and may determine the amount of chemical solution to be injected into the subject and the injection protocol. The injection protocol can also be locked with a password so that it cannot be changed.

Before injecting the chemical solution, the operator turns on the power of the injection device 100 and mounts the first syringe 91 and the second syringe 92 on the injection head 1. When the operator completes preparation for injection, the injection device 100 stands by in an injectable state. If necessary, the operator presses the stirring button 143 (FIG. 1) of the operation unit 14 to swing the first syringe 91. Thereafter, the operator presses the start button 142 (FIG. 1) of the operation unit 14 to start injecting the chemical solution.

Note that the operator may turn on the power of the injection device 100 after mounting the syringe. Further, the operator may start the injection of the chemical liquid by pressing a hand switch or a foot switch instead of the operation unit 14. Further, the injection device 100 can be configured so that the injection of the chemical solution is stopped by pressing the foot switch again.

As shown in FIG. 9, when the operator presses the stirring button 143 and inputs the stirring command of the stirring unit 3, the operation unit 14 transmits a stirring signal to the control unit 5 (S101). And the control part 5 which received the stirring signal controls the stirring unit 3, and the stirring unit 3 rocks | fluctuates the 1st syringe 91 according to predetermined stirring operation (S102). Specifically, the rotational motion from the stirring motor 32 is transmitted to the rotating member 124 via the transmission mechanism 33. Then, the holding member 11 swings together with the rotating member 124, and the first syringe 91 held by the holding member 11 swings.

The stirring unit 3 swings the holding member 11 around the axis of the first syringe 91 at a predetermined swing angle. That is, the control unit 5 determines the swing amount of the holding member 11 based on the detection signal from the swing detection unit 35. As a result, the holding member 11 is swung back and forth within a range of a predetermined angle from a horizontal direction with respect to a swing shaft positioned at the center of the rotating member 124. For example, in the stirring operation, the stirring time is 10 seconds to 300 seconds, and the rotation speed is 10 rpm to 120 rpm. Further, the stirring operation is performed so as to repeat swinging in one direction and swinging in the opposite direction.

As an example, the agitation unit 3 swings the holding member 11 180 degrees in one direction so that the first syringe 91 faces downward. Then, the agitation unit 3 swings the holding member 11 180 degrees in the reverse direction so that the first syringe 91 returns to the original position (origin). Thereafter, the stirring unit 3 swings the holding member 11 180 degrees in the reverse direction so that the first syringe 91 faces downward.

When the operator presses the start button 142 and inputs a chemical injection instruction, the operation unit 14 transmits an injection start signal to the control unit 5. And the control part 5 which received the injection | pouring start signal makes the chemical | medical solution judgment part 51 judge the chemical | medical solution to inject | pour. The drug solution determination unit 51 refers to the injection protocol and determines whether or not physiological saline is being injected. If the drug solution determination unit 51 determines that the physiological saline is not injected (NO in S103), the contrast agent is injected to the subject because it is a contrast agent injection command (S104). That is, the control unit 5 drives the actuator 22 of the first drive unit 2. Then, the actuator 22 advances the presser 21 through the presser pipe 23. Thereby, the presser 21 advances the piston 914 toward the tip of the first syringe 91. As a result, the contrast medium in the first syringe 91 is injected into the subject via the first tube 103.

When the chemical solution determination unit 51 determines that the physiological saline is injected (YES in S103), the control unit 5 controls the closing unit 16. And the closing part 16 closes the flow path of a contrast agent before pushing out the physiological saline. That is, the closing part 16 crushes the first tube 103 and closes the contrast agent flow path (S105). Specifically, the actuator 161 is driven, and the clamp member 162 crushes the first tube 103 in the guide portion 106. At the same time, the shielding member 163 shields the optical path of the closure detection unit 169. When the flow channel is normally closed, the closing detection unit 169 of the closing unit 16 detects the closing of the flow channel (YES in S106), and transmits a closing signal to the control unit 5.

The control unit 5 that has received the closing signal drives the actuator 62 of the second drive unit 6. Then, the actuator 62 advances the presser 61 through the presser pipe 63. Thereby, the presser 61 advances the piston 924 toward the tip of the second syringe 92. As a result, the physiological saline in the second syringe 92 is injected into the subject through the second tube 104 (S107).

In addition, when injecting the contrast medium and the physiological saline, the control unit 5 controls the injection time using a timer (not shown) and monitors the injection state such as the injection pressure of the drug solution. In addition, the control unit 5 displays the elapsed time from the start of injection on the display unit 13 by counting up. Further, the control unit 5 may cause the display unit 13 to display the time until the start of imaging on a countdown basis. Thereby, imaging can be started at an appropriate timing. According to the injection protocol as an example, the control unit 5 injects physiological saline to flush the contrast agent after injecting the contrast agent.

Thereafter, the control unit 5 causes the end determination unit 54 to determine whether or not the pushing out of the physiological saline has ended. When the driving of the second drive unit 6 stops, the end determination unit 54 determines that the physiological saline has been pushed out. Specifically, based on a signal received from the potentiometer that detects the rotation angle of the encoder 64 in the actuator 62 or the motor in the actuator 62, the end determination unit 54 determines to stop driving the second drive unit 6. . When the driving is stopped, the end determination unit 54 determines that the injection of the physiological saline has ended. On the other hand, when it is determined that the injection has not ended (NO in S108), the control unit 5 continues the injection of the physiological saline.

The closing part 16 opens the flow path of the contrast agent after the completion of the extrusion of the physiological saline. In other words, the closing portion 16 opens the flow path when the end determination portion 54 determines that the extrusion has ended. That is, when the end determination unit 54 determines that the extrusion has ended (YSE in S108), the control unit 5 controls the closing unit 16. Then, the closing portion 16 retracts the clamp member 162 from the guide portion 106 of the first tube 103 to open the contrast agent flow path (S109).

This causes the contrast agent channel to be closed and the contrast agent channel normally open only while physiological saline is being injected. When the injection of the physiological saline is completed, the flow path of the contrast medium is opened, and when the first syringe 91 is swung again, the process returns to S101 and each step is repeated. At this time, since the flow path is opened, the stirring unit 3 swings the first syringe 91 in a state where the closing portion 16 opens the contrast medium flow path. This eliminates the need to check the opening of the flow path before the first syringe 91 swings or before the contrast agent is injected. Furthermore, even if the presser 21 is moved forward by mistake, the microbubbles of the contrast agent can be prevented from being broken.

When the closing of the flow path is not detected, the closing detection unit 169 of the closing unit 16 does not transmit a closing signal to the control unit 5. If the control unit 5 does not receive the closing signal within a predetermined time after the closing unit 16 closes the flow path (NO in S106), the control unit 5 notifies the warning notification unit 52 of the error. The warning notification unit 52 displays a symbol or the like indicating an error on the display unit 13 (S110). This prompts the operator to check for channel closure. In addition, when the injection device 100 has a sound output unit, the warning notification unit 52 may cause the sound output unit to output a sound indicating an error.

Further, the operator can manually input the operation command of the second drive unit 6 via the operation unit 14. For example, the operator can advance the presser 61 to push out the physiological saline while pushing down the advance button of the operation unit 14. In this case, the operation unit 14 transmits a forward signal of the presser 61 to the control unit 5 as an injection start signal. The control unit 5 that has received the advance signal causes the chemical solution determination unit 51 to determine the chemical solution to be injected. And since the chemical | medical solution judgment part 51 is the advance signal of the presser 61, it judges that it is injection | pouring of the physiological saline. Upon receiving this determination result, the control unit 5 controls the closing unit 16, and the closing unit 16 closes the flow path of the contrast agent before pushing out the physiological saline.

When the flow channel is normally closed, the closing detection unit 169 of the closing unit 16 detects the closing of the flow channel and transmits a closing signal to the control unit 5. The control unit 5 that has received the closing signal drives the actuator 62 of the second drive unit 6. Thereby, the physiological saline in the second syringe 92 is injected through the second tube 104. Thereafter, the control unit 5 causes the end determination unit 54 to determine whether or not the pushing out of the physiological saline has ended. The end determination unit 54 determines that the pushing out of the physiological saline has ended when the input of the operation command via the operation unit 14 is stopped. When the end determination unit 54 determines that the injection has ended, the control unit 5 controls the closing unit 16 to open the contrast agent flow path.

As described above, the control unit 5 controls the first drive unit 2 and the second drive unit 6. And if the stirring command of the stirring unit 3 is input in the state where the 1st drive part 2 or the 2nd drive part 6 is operating, the control part 5 will ignore a stirring command or the 2nd drive part 6 Stop operation. That is, when the operator erroneously depresses the stirring button 143 and inputs the stirring command while the first driving unit 2 or the second driving unit 6 is operating, the control unit 5 ignores the stirring command or 2 The operation of the drive unit 6 is stopped. This prevents the agitating unit 3 from swinging the first syringe 91 while the first drive unit 2 or the second drive unit 6 is operating.

Further, when the contrast agent flow path is closed, the control unit 5 may notify the warning notification unit 52 of a warning when the operator erroneously presses the stirring button 143 and inputs a stirring command. Furthermore, the control unit 5 notifies the warning notification unit 52 of a warning when the operator accidentally depresses the forward button and inputs an operation command of the first drive unit 2 when the contrast agent flow path is closed. You may let them.

In addition, when an operator accidentally presses two types of buttons of the operation unit 14 simultaneously, for example, when the advance button and the stirring button 143 of the presser 61 are simultaneously pressed, the control unit 5 stops the injection device 100. Further, when the operator erroneously presses the operation button of the operation unit 14 during the injection of the chemical solution, for example, when the advance button of the presser 21 is pressed during the injection of the physiological saline, the control unit 5 causes the injection device 100 to Stop. However, instead of the injection device 100 being stopped, when two types of buttons are pressed at the same time, or when an operation button is pressed during the injection of the chemical solution, the control unit 5 inputs a command using the buttons. May be ignored.

[Limit detection unit]
Returning to FIG. 2, the injection device 100 includes a presser pipe 23 that is advanced or retracted by the first drive unit 2, and a limit detection unit 25 that detects a limit position of forward and backward movement of the presser pipe 23. Similarly, the injection device 100 includes a presser pipe 63 that is advanced or retracted by the second drive unit 6 and a limit detection unit 65 that detects the forward and backward limit positions of the presser pipe 63.

The limit detection unit 25 monitors the forward limit and the backward limit of the presser 21 by detecting the forward and backward limit positions of the presser pipe 23. Similarly, the limit detection unit 65 monitors the forward limit and the backward limit of the presser 61 by detecting the forward and backward limit positions of the presser pipe 63. When the detection signal from the limit detection unit 25 is received, the control unit 5 stops the presser 21 from moving forward or backward. Similarly, when the detection signal from the limit detection unit 65 is received, the control unit 5 stops the presser 61 from moving forward or backward.

The limit detection unit 25 and the limit detection unit 65 have the same structure. Therefore, description of the limit detection unit 25 is omitted, and the limit detection unit 65 will be described with reference to FIGS. 10 and 11. 10 shows the limit detector 65 viewed from the upper front side, and FIG. 11 shows a cross section along the longitudinal direction of the limit detector 65 extending in the vertical direction. 10 and 11 show a state where the presser pipe 63 is advanced to the limit position.

As shown in FIG. 10, the limit detection unit 65 includes a first limit detection unit 651 that detects a backward limit position, and a second limit detection unit 653 that detects a forward limit position. The first limit detection unit 651 and the second limit detection unit 653 are optical slit sensors. Further, the presser pipe 63 is formed with a first light transmission portion 652 and a second light transmission portion 654 (FIG. 11). The first light transmission part 652 and the second light transmission part 654 are holes that penetrate the presser pipe 63.

As shown in FIG. 11, when the presser pipe 63 reaches the forward limit position, the second light transmission unit 654 detects the light transmitted through the second light transmission unit 654 by the second limit detection unit 653. It is set to be. Similarly, the position of the first light transmission unit 652 is set so that the first limit detection unit 651 detects the light transmitted through the first light transmission unit 652 when the presser pipe 63 reaches the retreat limit position. Has been.

When the second limit detection unit 653 detects light transmitted through the second light transmission unit 654, the limit detection unit 65 transmits a detection signal to the control unit 5. Then, the control unit 5 that has received the detection signal controls the second drive unit 6. Thereby, the 2nd drive part 6 stops the advance of the presser 61. FIG. Similarly, when the first limit detection unit 651 detects light transmitted through the first light transmission unit 652, the limit detection unit 65 transmits a detection signal to the control unit 5. Then, the control unit 5 that has received the detection signal controls the second drive unit 6. As a result, the second drive unit 6 stops the retreat of the presser 61. By detecting the forward and backward limit positions with such a configuration, the injection device 100 can be downsized for the following reason.

For example, the limit detection unit described in Patent Document 1 includes a front limit detection unit and a rear limit detection unit that are optical slit sensors. And the shielding board is being fixed to the rear-end part of a screw shaft, and if a presser advances to a limit, a front side limit detection part will be shielded by a shielding board. Further, the rear limit detection unit is shielded by the shielding plate when the presser moves back to the limit.

Therefore, the screw shaft needs a rear end portion having a length corresponding to the distance between the front limit detection portion and the rear limit detection portion. As a result, the size of the injection device is increased. However, according to the limit detection unit 65 according to the first embodiment, the rear end portion of the screw shaft for detecting the forward limit and the backward limit becomes unnecessary. As a result, the injection device 100 can be further downsized.

In addition, the presser pipe 63 has a hollow portion 632 and a solid portion 634. The first light transmission part 652 is formed in the hollow part 632, and the second light transmission part 654 is formed in the solid part 634. That is, at least a part of the solid part 634 exists between the first light transmission part 652 and the second light transmission part 654. Thereby, even if the chemical solution enters the first light transmitting portion 652, the solid portion 634 prevents the intrusion into the injection head 1.

Note that the first light transmitting portion 652 and the second light transmitting portion 654 can be filled with a light transmitting resin or the like. However, if the first light transmitting portion 652 and the second light transmitting portion 654 are through holes extending in the direction of gravity, the chemical solution or the like that has entered the through holes can be discharged out of the apparatus by gravity.

According to the injection device 100 according to the first embodiment, a space for mounting and driving the three-way cock is not required. Thereby, injection device 100 can be reduced in size, preventing destruction of microbubbles. Further, the closing part 16 opens the flow path of the first chemical liquid after the second chemical liquid is injected. Thereby, the stirring unit 3 can swing the first syringe 91 in a state where the closing portion 16 opens the flow path of the contrast agent. Furthermore, the limit detecting unit 65 according to the first embodiment does not require the rear end portion of the screw shaft for detecting the forward and backward limit positions, so that the injection device 100 can be further downsized.

The control unit 5 may control the actuator 22 of the first drive unit 2 not to be driven when the closure signal is received from the closure unit 16. Moreover, the control part 5 may control the 1st drive part 2 so that injection may not be started during stirring operation. In this case, the control unit 5 starts the injection of the chemical solution after the holding member 11 stops swinging. Therefore, when the injection start signal is received during the stirring operation, the control unit 5 drives the actuator 22 after the stirring operation is finished. Thereby, the first tube 103 is not moved by the swinging operation during the injection, and the catheter or the like can be prevented from being detached from the subject.

Also, the control unit 5 can cause the stirring unit 3 to automatically perform the stirring operation when starting the injection. In this case, the control unit 5 that has received the injection start signal causes the stirring unit 3 to perform the stirring operation, and drives the actuator 22 after the stirring operation is completed. In addition, the stirring operation can be automatically started when the separation of the chemical solution is detected. The separation of the chemical solution can be detected by a turbidity detection unit or the like, and the control unit 5 starts the stirring operation when receiving the detection signal. Furthermore, the operator can also set to perform a stirring operation automatically every predetermined time. If necessary, a stirring operation may be performed during the injection of the chemical solution.

[Second Embodiment]
Control according to the second embodiment will be described with reference to FIG. FIG. 12 is a flowchart illustrating the closing of the flow path according to the second embodiment. Further, in the description of the second embodiment, differences from the first embodiment will be described, the same reference numerals will be given to the components described in the first embodiment, and description thereof will be omitted. Except where specifically described, the constituent elements having the same reference numerals perform substantially the same operations and functions, and the effects thereof are also substantially the same.

[Flow path closing flow]
As in the first embodiment, the injection device 100 includes a control unit 5 that controls the first drive unit 2, the second drive unit 6, the stirring unit 3, and the closing unit 16, and a memory unit 53 as a storage unit. ing. Moreover, the control part 5 has the chemical | medical solution judgment part 51 which judges the chemical | medical solution to inject | pour, the warning alerting | reporting part 52 which alert | reports an error, and the completion | finish judgment part 54 which judges the completion | finish of extrusion of a 2nd chemical | medical solution. The second embodiment differs from the first embodiment in that the contrast agent flow path is normally closed.

When the operator completes preparation for injection, the injection device 100 stands by in an injectable state. Specifically, the operator depresses the check button of the operation unit 14 after arranging the first tube 103 on the guide unit 106. Accordingly, the control unit 5 that has received the signal from the operation unit 14 controls the closing unit 16. And the closing part 16 crushes the 1st tube 103, and closes the flow path of a contrast agent. In this state, the injection device 100 stands by. Thereafter, the operator presses the stirring button 143 (FIG. 1) of the operation unit 14 to swing the first syringe 91.

As shown in FIG. 12, when the operator presses the stirring button 143 and inputs the stirring command of the stirring unit 3, the operation unit 14 transmits a stirring signal to the control unit 5 (S201). In the second embodiment, since the flow path of the contrast medium is normally closed, the closing portion 16 opens the flow path of the contrast medium when the stirring command of the stirring unit 3 is input. Specifically, the closing portion 16 retracts the clamp member 162 from the guide portion 106 of the first tube 103 to open the contrast agent flow path (S202).

When the flow path is not normally opened, the closing detection unit 169 of the closing unit 16 continues to transmit a closing signal to the control unit 5. The control unit 5 determines that the opening of the flow channel is not detected when the closing signal is received even after a predetermined time has elapsed since the closing unit 16 opened the flow channel (NO in S203). The warning notification unit 52 is controlled. And the warning alerting | reporting part 52 displays the symbol etc. which show an error on the display part 13 (S204). This prompts the operator to check for channel closure. Thereafter, the control unit 5 does not perform the stirring operation until the stirring signal is input again.

When the flow path is normally opened, the closing detection unit 169 of the closing unit 16 does not transmit a closing signal to the control unit 5. When the control unit 5 stops receiving the closing signal, it determines that the opening of the flow path has been detected (YES in S203). And the control part 5 controls the stirring unit 3, and the stirring unit 3 rocks | fluctuates the 1st syringe 91 according to predetermined stirring operation (S205). Thereby, the stirring unit 3 can swing the first syringe 91 in a state where the closing portion 16 opens the flow path of the contrast agent.

Furthermore, the control unit 5 causes the end determination unit 54 to determine whether or not the swinging of the first syringe 91 has ended. Specifically, the end determination unit 54 determines stop of the stirring motor 32 based on a signal received from the encoder 321 of the stirring motor 32 or the potentiometer in the stirring unit 3. When the stirring motor 32 is stopped, the end determination unit 54 determines that the swinging of the first syringe 91 has ended. On the other hand, when the end determination unit 54 determines that the swing has not ended (NO in S206), the control unit 5 continues the swing of the first syringe 91.

When the end determination unit 54 determines that the swinging has ended (YES in S206), the control unit 5 controls the closing unit 16. Then, the closing unit 16 crushes the first tube 103 to close the contrast agent flow path (S207). When the flow channel is normally closed, the closing detection unit 169 of the closing unit 16 detects the closing of the flow channel and transmits a closing signal to the control unit 5. When the operator presses the start button 142, the operation unit 14 transmits an injection start signal to the control unit 5. And the control part 5 which received the injection | pouring start signal makes the chemical | medical solution judgment part 51 judge the chemical | medical solution to inject | pour. The drug solution determination unit 51 refers to the injection protocol and determines whether or not the contrast agent is injected.

If the drug solution determination unit 51 determines that the contrast agent is not injected (NO in S208), the physiological saline is injected into the subject because of the physiological saline injection command (S212). In the second embodiment, since the flow path of the contrast medium is normally closed, it is not necessary to close the flow path before injecting physiological saline. Therefore, it is not necessary to check the closing of the flow path before the injection of physiological saline.

When injecting physiological saline, the control unit 5 drives the actuator 62 of the second drive unit 6. Then, the actuator 62 advances the presser 61 through the presser pipe 63. Thereby, the presser 61 advances the piston 924 toward the tip of the second syringe 92. As a result, the physiological saline in the second syringe 92 is injected into the subject. Thereafter, the control unit 5 stands by until the contrast agent is injected. In the second embodiment, since the contrast agent channel is normally closed, it is not necessary to open the channel after injection of physiological saline.

If the chemical solution determination unit 51 determines that the contrast agent is injected (YES in S208), the control unit 5 controls the closing unit 16. Then, the closing portion 16 retreats the clamp member 162 from the guide portion 106 of the first tube 103 to open the contrast agent flow path (S209). When the flow path is not normally opened, the closing detection unit 169 of the closing unit 16 continues to transmit a closing signal to the control unit 5. The control unit 5 determines that the opening of the flow path has not been detected when the closing signal is received even after a predetermined time has elapsed since the closing part 16 was opened (NO in S210). ), The warning notification unit 52 is notified of the warning (S213). This prompts the operator to check the opening of the flow path. Thereafter, the controller 5 does not perform the injection operation until the injection start signal is input again.

When the flow path is normally opened, the closing detection unit 169 of the closing unit 16 does not transmit a closing signal to the control unit 5. When the control unit 5 does not receive the closing signal, it determines that the opening of the flow path has been detected (YES in S210). Thereafter, the control unit 5 drives the actuator 22 of the first drive unit 2. Then, the actuator 22 advances the presser 21 through the presser pipe 23. Thereby, the presser 21 advances the piston 914 toward the tip of the first syringe 91. As a result, the contrast medium in the first syringe 91 is injected into the subject (S211).

Thereafter, the control unit 5 causes the end determination unit 54 to determine whether or not the extrusion of the contrast agent has ended. When the driving of the first drive unit 2 is stopped, the end determination unit 54 determines that the extrusion of the contrast agent has ended. Specifically, based on a signal received from the potentiometer that detects the rotation angle of the encoder 24 in the actuator 22 or the motor in the actuator 22, the end determination unit 54 determines whether to stop driving the first drive unit 2. . When the driving is stopped, the end determination unit 54 determines that the injection of the contrast agent has ended. When the end determination unit 54 determines that the extrusion of the contrast agent has ended, the closing unit 16 crushes the first tube 103 in the same manner as described above to close the contrast agent flow path.

According to the injection device 100 according to the second embodiment, a space for mounting and driving the three-way stopcock becomes unnecessary. Thereby, injection device 100 can be reduced in size, preventing destruction of microbubbles. Further, the closing part 16 opens the flow path of the first chemical liquid after the second chemical liquid is injected. Thereby, the stirring unit 3 can swing the first syringe 91 in a state where the closing portion 16 opens the first tube 103. In addition, since the contrast agent channel is normally closed, it is not necessary to close the channel before injecting physiological saline.

[Third Embodiment]
With reference to FIG.13 and FIG.14, the injection apparatus 300 of 3rd Embodiment which has automatic stirring mode is demonstrated. FIG. 13 is a schematic block diagram of an injection apparatus 300 according to the third embodiment. FIG. 14 is a flowchart for explaining the automatic stirring mode. In the description of the third embodiment, differences from the first and second embodiments will be described, the same reference numerals will be given to the components described in the first and second embodiments, and the description thereof will be omitted. . Except where specifically described, the constituent elements having the same reference numerals perform substantially the same operations and functions, and the effects thereof are also substantially the same.

As shown in FIG. 13, the injection device 300 includes a control unit 5 that controls the first drive unit 302, the second drive unit 306, the stirring unit 3 and the closing unit 16, and a memory unit 53 as a storage unit. Yes. The control unit 5 has a timer (not shown). The control unit 5 is a CPU which is a one-chip microcomputer, for example, and executes the processing operation of the entire injection apparatus 300 according to a program stored in the memory unit 53 in advance. The memory unit 53 includes a RAM, a ROM, or a hard disk drive.

The first drive unit 302 includes a motor (not shown) (for example, a DC motor), and pushes out the first drug solution (contrast agent) from the first syringe 91. Moreover, the 1st drive part 302 differs from 1st and 2nd embodiment by the point provided with the 1st detection part 329 which detects the injection pressure of a 1st chemical | medical solution. The first detector 329 measures the current value of the current supplied to the motor, and obtains the injection pressure based on the measured current value. Alternatively, the current value measured by the first detection unit 329 may be transmitted to the control unit 5, and the control unit 5 may obtain the injection pressure based on the received current value. The control unit 5 controls the first driving unit 302 so as not to exceed a predetermined maximum injection pressure during the injection of the first chemical solution. The first detection unit 329 may be a load cell.

Similarly, the second drive unit 306 includes a motor (not shown) (for example, a DC motor), and pushes out the second drug solution (saline) from the second syringe 92. The second drive unit 306 is different from the first and second embodiments in that it includes a second detection unit 369 that detects the injection pressure of the second chemical solution. The second detector 369 measures the current value of the current supplied to the motor and obtains the injection pressure based on the measured current value. Alternatively, the current value measured by the second detection unit 369 may be transmitted to the control unit 5, and the control unit 5 may obtain the injection pressure based on the received current value. The control unit 5 controls the second driving unit 306 so as not to exceed a predetermined maximum injection pressure during the injection of the second chemical solution. Note that the second detection unit 369 may be a load cell.

The stirring unit 3 includes a stirring motor 32 and swings the first syringe 91. The stirring unit 3 has a swing detection unit 35 that detects a swing angle. The closing unit 16 closes the flow path in the first tube 103 connected to the first syringe 91. The closing part 16 includes a closing detection part 169 that detects the closing of the flow path in the first tube 103.

[Automatic stirring mode]
The injection device 300 of the third embodiment has an automatic stirring mode in which the stirring operation is automatically repeated every predetermined time (for example, 30 seconds to 60 seconds). This automatic stirring mode will be described with reference to FIGS. 13 and 14.

Before the chemical solution is injected, the operator turns on the power of the injection device 300. At this time, when the flow path is closed, the closing portion 16 opens the flow path. Moreover, when the holding member 11 (FIG. 1) has shifted | deviated from the origin, the stirring unit 3 moves the holding member 11 to the original position. Then, the operator mounts the first syringe 91 and the second syringe 92 on the injection head 1. Subsequently, the operator presses the forward button 145 </ b> A of the operation unit 14. As a result, the presser 21 of the first drive unit 302 moves forward and comes into contact with the rear end of the piston 914 of the first syringe 91. Similarly, the operator presses the forward button 145B to bring the presser 61 of the second drive unit 306 into contact with the rear end of the piston 924 of the second syringe 92. The operator may previously move the presser 21 and the presser 61 to a predetermined position by pressing the forward button 145A or the backward button 146A, or the forward button 145B or the backward button 146B.

Thereafter, the operator presses the stirring button 143 of the operation unit 14 to start the automatic stirring mode in order to stir the first chemical solution (S301). That is, when the stirring button 143 is pressed and a stirring command of the stirring unit 3 is input, the operation unit 14 transmits a stirring signal to the control unit 5. And the control part 5 which received the stirring signal controls the stirring unit 3, and the stirring unit 3 rocks the 1st syringe 91 according to the predetermined initial stirring operation (S302).

In the initial stirring operation, for example, the stirring unit 3 swings the holding member 11 180 degrees in the first direction so that the first syringe 91 faces downward. Then, after stopping for a predetermined time (for example, 2 seconds), the agitation unit 3 moves the holding member 11 in the direction opposite to the first direction so that the first syringe 91 passes through the original position (origin) and faces downward. Swing 360 degrees in the second direction. Subsequently, after stopping for a predetermined time (for example, 2 seconds), the stirring unit 3 swings the holding member 11 in the first direction by 180 degrees so that the first syringe 91 returns to the original position.

At this time, when the swing angle of the swing in the second direction is 370 degrees or more or 350 degrees or less, the control section 5 causes the warning notification section 52 (FIG. 8) to notify the warning. When the warning is notified, the control unit 5 cancels the automatic stirring mode.

In the automatic stirring mode, the control unit 5 refers to the information from the timer and automatically repeats the same stirring operation as the initial stirring operation every predetermined time (S303). Alternatively, a stirring operation different from the initial stirring operation, for example, an operation of swinging 180 degrees in the first direction and then swinging 180 degrees in the second direction may be repeated. During this automatic stirring, the stirring button 143 blinks to display the automatic stirring mode. The operator operates the input key 141 of the operation unit 14 to input the injection speed and the injection amount to the control unit 5. The display unit 13 displays the injection speed and the injection amount, and the operator can check the contents. The input item is changed every time the selection button 147 is pressed.

After this input, the operator punctures the subject with the needle and presses the standby button 148 on the operation unit 14. Thereby, the preparation for injection is completed, and the injection device 300 stands by in an injectable state. At this time, the lamp 140 of the operation unit 14 is turned on to display a standby state. During the preparation and waiting for injection, the automatic agitation mode is continued. Then, during the automatic stirring, the control unit 5 determines whether or not to stop the automatic stirring mode (S304). Specifically, when the condition for mode stop is satisfied (YES in S304), the control unit 5 stops the automatic stirring mode (S305). The mode stop condition is, for example, pressing of the start button 142 of the operation unit 14, pressing of the forward buttons 145A and 145B, pressing of the backward buttons 146A and 146B, or reception of a closing signal.

As an example, when the operator presses the start button 142, the control unit 5 that has received the injection start signal stops the automatic stirring mode halfway and injects the chemical solution. At this time, the control unit 5 stops the automatic stirring mode even in the middle of swinging (for example, the state where the first syringe 91 faces downward). This is because importance is placed on the start timing of injection of the chemical solution. However, the automatic stirring mode may alternatively be stopped after the end of rocking. For example, the automatic stirring mode may be stopped after the first syringe 91 is swung until it faces upward. By stopping the automatic stirring mode, swinging while the first drive unit 302 or the second drive unit 306 is driven can be prevented.

Thereafter, when the condition for resuming the mode is satisfied (YES in S306), the control unit 5 resumes the automatic stirring mode (S303). The condition for restarting the mode is, for example, completion of injection of the second chemical solution. That is, when the end determination unit 54 (FIG. 8) determines that the injection of the second chemical liquid has ended, the control unit 5 resumes the automatic stirring mode. At this time, if a predetermined time in the automatic stirring mode has elapsed during the injection of the chemical solution, the stirring unit 3 swings simultaneously with the restart. When the mode restart condition is not satisfied (NO in S306), the control unit 5 continues to stop the automatic stirring mode.

Furthermore, during automatic stirring, the control unit 5 determines whether or not to cancel the automatic stirring mode (S307). Specifically, when the condition for canceling the mode is satisfied (YES in S307), the control unit 5 cancels the automatic stirring mode and ends the automatic stirring mode. When the automatic stirring mode ends, the stirring button 143 is turned off. The condition for releasing the mode is, for example, pressing down of the auto return button 149 of the operation unit 14, completion of injection of the first chemical liquid or the second chemical liquid, pressing down of the backward button 146A, pressing down of the stirring button 143, or notification of a warning. is there. By canceling the automatic stirring mode, it is possible to prevent rocking when stirring is unnecessary. When the condition for canceling the mode is not satisfied (NO in S307), the control unit 5 continues the automatic stirring mode (S303).

As an example, when the operator presses the auto return button 149, the second drive unit 306 moves the presser 61 back to a predetermined position via the presser pipe 63. At this time, the control unit 5 cancels the automatic stirring mode after swinging until the first syringe 91 faces upward. Thereby, repetition of stirring operation stops. Alternatively, the control unit 5 may cancel the automatic stirring mode in the middle of swinging (for example, the state where the first syringe 91 faces downward). The operator can restart the automatic stirring mode by pressing the stirring button 143.

In the standby state, when the operator presses the stop button 144 of the operation unit 14, the standby state is released. Further, when the operator presses the stop button 144 of the operation unit 14 during the injection of the chemical liquid, the injection of the chemical liquid is stopped. However, when the first chemical solution remains in these situations, stirring is necessary, so the automatic stirring mode is not released. When the operator presses the stop button 144 in the state of automatic stirring other than the standby state and during the injection of the chemical solution, the automatic stirring mode may be canceled.

Further, the control unit 5 may cancel the automatic stirring mode when the holding member 11 is swung by an external force. As an example, the control unit 5 cancels the automatic agitation mode when the swing detection unit 35 (FIG. 3) detects swing of a predetermined angle (for example, 90 degrees) other than during swing.

The order of the above procedures can be changed as appropriate. For example, the operator may turn on the power of the injection device 300 after mounting each syringe. Further, the operator may start the automatic stirring mode after pressing the standby button 148.

According to the injection device 300 according to the third embodiment, a space for mounting and driving a three-way cock is not required. Thereby, injection device 300 can be reduced in size, preventing destruction of microbubbles. Further, since the stirring is automatically repeated, it is not necessary for the operator to press the stirring button 143 each time. Thereby, while being able to reduce an operator's operation | work, separation of a contrast agent can be suppressed automatically.

The control unit 5 may control the injection pressure of the first chemical solution or the second chemical solution to be lower than the limit injection pressure at which the microbubbles collapse. In this case, the control unit 5 acquires the limit injection pressure stored in advance from the memory unit 53. Then, the control unit 5 controls the first driving unit 302 or the second driving unit 306 so as not to reach the limit injection pressure. Further, the control unit 5 may acquire the limit injection pressure from a data carrier such as an RFID or a barcode disposed in the first syringe 91 or the second syringe 92. The controller 5 can read the information recorded from the data carrier via the injection head 1. The limit injection pressure can be obtained by experiments.

The memory unit 53 may store a plurality of limit injection pressures set for each thickness of a needle punctured by the subject. This critical injection pressure can be set to increase as the needle becomes thicker. For example, the limit injection pressure for a 21G needle is set higher than a 22G needle and lower than a 20G needle.

Further, the control unit 5 controls the second driving unit 306 so as to stop the first chemical solution in the third tube 105 by pushing out the first chemical solution after the first chemical solution is pushed out by the second chemical solution. May be. That is, the control unit 5 may control the second drive unit 306 so as to move the contrast agent to a position close to the catheter after the injection of the contrast agent. In this case, the control unit 5 acquires the injection amount of the second chemical solution corresponding to the third tube 105 from the memory unit 53. Then, the control unit 5 causes the second driving unit 306 to inject the second injection of the acquired injection amount so that the first chemical stops at a predetermined position in the third tube 105.

Depending on the length of the third tube 105, the amount of physiological saline necessary to move the contrast agent varies. Therefore, the control unit 5 may determine the necessary amount of physiological saline injected according to the length (type) of the third tube 105. Thereby, the shift | offset | difference of the timing when a chemical | medical solution is inject | poured into a body and the timing which an injection | pouring apparatus starts injection | pouring can be reduced, and the fall of an image quality can be suppressed. Further, even when a plurality of types of tubes having different lengths are used, the contrast agent can be pushed and advanced to an appropriate position.

[Modification]
The present invention has been described above with reference to each embodiment. However, the present invention is not limited to the above embodiment. Inventions modified within the scope not departing from the present invention and inventions equivalent to the present invention are also included in the present invention. In addition, the above-described embodiments and modifications can be combined as appropriate without departing from the scope of the present invention.

For example, an ultrasonic motor can be used for each motor. Further, although the holding portion 12 is fixed, it can be swung similarly to the holding member 11. The injection devices 100 and 300 can also be used with other medical imaging devices other than the ultrasonic diagnostic device. Examples of such medical imaging apparatuses include an MRI (Magnetic Resonance Imaging) apparatus, a CT (Computed Tomography) apparatus, an angio imaging apparatus, a PET (Positron Emission Tomography) apparatus, a SPECT (Single Photon Emission Computed Tomography) apparatus, and a CT. There are various medical imaging apparatuses such as an angio apparatus, MR angio apparatus, and blood vessel imaging apparatus.

Also, the injection devices 100 and 300 can be connected to the imaging device by wire or wirelessly. In this case, various types of data are transmitted and received between the imaging device and the injection devices 100 and 300 when the chemical solution is injected and when an image is taken. For example, the imaging conditions may be set or displayed on the injection devices 100 and 300, and the injection conditions may be set or displayed on the imaging device.

In addition, the injection devices 100 and 300 send information on injection results (injection history and agitation operation history) via a network via RIS (Radiology Information System), PACS (Picture Architecture and Communication System), and HIS (Hospital Information System) It can also be transmitted and stored in an external storage device. In this case, the history of the stirring operation may include data such as the name of the chemical solution, the stirring time, and the rocking speed. In addition, the injection history may include data such as the name of the chemical solution, the injection speed, the injection amount, the injection time, and the maximum injection pressure. In addition, when injection device 100,300 is provided with a communication part, information about an imaging result, for example, examination ID, imaging time, an imaging part, etc. can also be acquired from an ultrasonic diagnostic device via a communications part. The injection devices 100 and 300 can store the injection result associated with the imaging result in the external storage device. The operator can also send and receive information such as the injection protocol to the injection device using the terminal of the hospital information system.

Also, the syringe can be provided with a data carrier such as an RFID or a barcode. In this data carrier, information on the filled chemical solution is recorded. The injection devices 100 and 300 can read the information recorded from the data carrier via the injection head 1. For example, the injection devices 100 and 300 can display information on the read chemical solution on the display unit 13 of the injection head 1. In addition, as information of a chemical | medical solution, there exist a product name, a chemical | medical agent name, product ID, a chemical classification, a containing component, a density | concentration, a viscosity, a syringe capacity | capacitance, a syringe pressure | voltage resistant, a cylinder internal diameter, a piston stroke etc.

The control unit 5 acquires the filling time of the chemical solution from the memory unit 53, refers to the information from the timer, and gives an error to the warning notification unit 52 when a predetermined time (for example, 1 to 2 hours) has elapsed from the filling time. May be notified. This filling date and time can be input to the memory unit 53 from the operation unit 14 by the operator. Accordingly, it is possible to prompt the operator to inject the chemical before the microbubbles collapse due to the lapse of the usable time. Alternatively, the control unit 5 may automatically store the mounting time of the syringe in the memory unit 53 and notify the warning notification unit 52 of an error when a predetermined time has elapsed from the mounting time.

[Appendix]
A part or all of the above-described embodiment can be described as in the following supplementary notes, but is not limited thereto.

(Additional remark 1) The 1st drive part which extrudes the said 1st chemical | medical solution from the 1st syringe with which the 1st chemical | medical solution was filled, The closing part which closes the flow path in the tube connected to the said 1st syringe, The said 1st A control method for an injection device comprising a stirring unit for swinging a syringe, wherein the first syringe is swung by the stirring unit in a state where the closing portion opens the flow path.

(Supplementary Note 2) A drive unit that pushes out the chemical solution from a syringe filled with a chemical solution, a presser pipe that is advanced or retracted by the drive unit, and a limit detection unit that detects the forward and backward limit positions of the presser pipe The presser pipe is further provided with a first light transmission part and a second light transmission part, and the positions of the first light transmission part and the second light transmission part are at the forward limit position. The limit detection unit detects the light transmitted through the first light transmission unit when it reaches, and the limit detection unit detects the light transmitted through the second light transmission unit when it reaches the retreat limit position. An infusion device that is set to detect.

(Supplementary Note 3) A control method for an injection apparatus comprising: a first drive unit that pushes out the first chemical solution from a first syringe filled with a first chemical solution; and a stirring unit that rocks the first syringe, A control method in which the stirring unit automatically repeats the stirring operation every predetermined time.

(Supplementary Note 4) A first drive unit that pushes out the first chemical solution from the first syringe filled with the first chemical solution, and a stirring unit that automatically repeats the stirring operation of swinging the first syringe every predetermined time. Injection device.

(Additional remark 5) Control of injection | pouring apparatus provided with the drive part which extrudes the said chemical | medical solution from the syringe with which the chemical | medical solution containing a microbubble was filled, the detection part which detects the injection pressure of the said chemical | medical solution, and the stirring unit which rocks | fluctuates the said syringe It is a method, Comprising: The said drive part is driven so that the said injection pressure may not exceed predetermined pressure, The said predetermined pressure is set to the pressure which does not collapse the said microbubble.

(Additional remark 6) The drive part which extrudes the said chemical | medical solution from the syringe with which the chemical | medical solution containing microbubble was filled, the detection part which detects the injection pressure of the said chemical | medical solution, the stirring unit which rocks | fluctuates the said syringe, and the said injection pressure are predetermined And a control unit that drives the driving unit so as not to exceed the pressure, and the predetermined pressure is set to a pressure that does not cause the microbubbles to collapse.

This application claims priority from Japanese Patent Application No. 2016-80957 filed on Apr. 14, 2016, the entire contents of which are incorporated herein by reference.

2: 1st drive part, 3: Stirring unit, 5: Control part, 6: 2nd drive part, 14: Operation part, 16: Closure part, 52: Warning notification part, 54: Completion judgment part, 63: Presser pipe , 65: limit detection unit, 91: first syringe, 92: second syringe, 100: injection device, 103: first tube, 300: injection device, 302: first driving unit, 306: second driving unit, 652 : 1st light transmission part, 654: 2nd light transmission part

Claims (9)

1. A first drive unit for pushing out the first chemical solution from the first syringe filled with the first chemical solution;
   A closing portion for closing a flow path in a tube connected to the first syringe;
   An injection device comprising: an agitation unit that swings the first syringe in a state where the closing portion opens the flow path.
2. The injection device according to claim 1, wherein the closing portion opens the flow path before the stirring unit swings the first syringe.
3. The injection device according to claim 2, wherein the closing part opens the flow path when a stirring command of the stirring unit is input.
4. A second drive unit for extruding the second chemical solution from the second syringe filled with the second chemical solution;
   The said closing part closes the said flow path before pushing out the said 2nd chemical | medical solution, and opens the said flow path after the extrusion of the said 2nd chemical | medical solution is complete | finished. Injection device.
5. An end determination unit for determining the end of the extrusion of the second chemical solution;
   The termination determining unit determines that the extrusion is terminated when the driving of the second driving unit is stopped,
   The injection device according to claim 4, wherein the closing part opens the flow path when the end determination part determines that the extrusion has ended.
6. An end determination unit for determining the end of the extrusion of the second chemical solution;
   An operation unit for inputting an operation command of the second drive unit;
   The injection device according to claim 4, wherein the end determination unit determines that the extrusion has ended when the input of the operation command is stopped.
7. A control unit for controlling the first driving unit and the second driving unit;
   When the stirring command of the stirring unit is input in a state where the first driving unit or the second driving unit is operating, the control unit ignores the stirring command or operates the second driving unit. The injection device according to any one of claims 4 to 6, wherein the injection is stopped.
8. 8. The apparatus according to claim 1, further comprising a warning notification unit that issues a warning when a stirring command of the stirring unit or an operation command of the first drive unit is input when the flow path is closed. The injection device according to item 1.
9. A presser pipe in which a first light transmission part and a second light transmission part are formed;
   A limit detection unit for detecting a limit position for forward and backward movement of the presser pipe;
   The positions of the first light transmission part and the second light transmission part are such that the limit detection part detects the light transmitted through the first light transmission part when the forward limit position is reached, and the backward movement is performed. The injection device according to any one of claims 1 to 8, wherein the limit detection unit is set to detect light transmitted through the second light transmission unit when the limit position is reached.

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