WO2017166567A1

WO2017166567A1 - Synergistic plant growth regulator composition

Info

Publication number: WO2017166567A1
Application number: PCT/CN2016/094032
Authority: WO
Inventors: 仲汉根; 季红进
Original assignee: 江苏辉丰农化股份有限公司
Priority date: 2016-04-02
Filing date: 2016-08-08
Publication date: 2017-10-05
Also published as: CN106922714A; CN106342853B; CN106342853A

Abstract

Provided are a synergistic plant growth regulator composition, and a method for preparing the composition and the use thereof. The effective ingredients of the composition comprise active components A and B, wherein the active component A is thidiazuron, and the active component B is diethyl aminoethyl hexanoate; and the weight ratio of the active component A to the active component B is 1:0.7-140. The composition can effectively regulate the growth of crops, increase the disease resistance and stress resistance thereof, promote the health benefits of crops and increase the yield of crops.

Description

Synergistic plant growth regulator composition

Technical field

The invention belongs to the field of agricultural plant protection, in particular to a plant growth regulator composition with improved properties, in particular to a composition comprising a thiazole and an amine fresh pesticide.

Background technique

Diethyl aminoethyl hexanoate is a high-energy plant growth regulator with broad-spectrum and breakthrough effects. It can increase the activity of plant peroxidase and nitrate reductase, increase the content of chlorophyll to accelerate photosynthetic rate, and promote plants. The division and elongation of cells promote the development of roots and regulate the balance of nutrients in the body. It has high bioactive compounds for a variety of crops with significant effects of increasing yield, stress resistance, disease resistance, quality improvement, and early maturity. It can be compounded with various elements, and can also be combined with fungicides to enhance the disease resistance of plants and enhance the sterilization effect. It can be used alone or in combination with fertilizers, fungicides, insecticides and herbicides.

Pyraclostrobin is a new type of high-efficiency plant growth regulator. When it is absorbed by plants, it can promote the separation of petioles and stems and form natural shedding. It can be widely used in pesticides and fertilizers. It has strong biological activity, and its ability to induce plant cell division and callus formation is many times higher than that of general cytokinins. Improve crop absorptive capacity and increase photosynthesis, so as to increase production and enhance the purpose. It can be used in various kinds of melons, fruits, vegetables, seedlings, flowers, food, tobacco and other crops, and can also be used for tissue culture, genetic engineering, etc. In production, it can significantly improve crop yield, improve quality and use less, has no pollution to the ecological environment, and is non-toxic to humans, animals, birds, bees and natural enemies.

The plant growth regulators currently on the market are mainly based on a single agent, and the effect is single.

Summary of the invention

It is an object of the present invention to provide a plant growth regulator composition for promoting crop growth, improving crop disease resistance, crop yield and improving crop quality. The inventors have found that there is a significant synergistic effect between the amine fresh ester and the thiene on the regulation or promotion of plant growth.

Another object of the present invention is to provide a process for the preparation of a composition comprising two active ingredients A and B plant growth regulators and for regulating and promoting the growth of crops in the agricultural field.

The object of the invention can be achieved by the following measures:

A synergistic plant growth regulator composition comprising two active components A and B, Wherein the active component A is thiabendazole and the active component B is an amine fresh ester, and the weight ratio between the two components is from 1:0.7 to 140 by weight of the active component A and the active component B.

In a preferred embodiment, the weight ratio of the active component A to the active component B is 1:0.75-130. To further enhance the synergistic effect, the weight ratio of the active component A to the active component B is 1:0.8. ~120.

In a preferred embodiment, the weight ratio between the two components of A and B can be arbitrarily adjusted within the range of the following ratios: 1:0.7, 1:0.75, 1:0.8, 1:0.85, 1: 0.9, 1:0.95, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:15, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1: 80, 1:85, 1:90, 1:95, 1:100, 1:110, 1:115, 1:120, 1:125, 1:130, 1:135 or 1:140, can also be above Choose within the range of any two ratios.

The inventors have found through experiments that the composition of the present invention can be used to better regulate the growth of crops, promote the health effects of crops, increase crop yield, and improve crop quality; therefore, the pesticide composition of the present invention can be applied to agricultural fields. Promote or regulate plant growth.

The invention provides the use of a composition comprising component A (thiabendazole) and component B (amine fresh ester) to regulate crop growth in the agricultural field, in particular to regulate crop growth in rice, corn or fruit trees to improve disease resistance Other uses.

In order to fully exert the advantageous effects of the present invention, the composition of the present invention can also be used in combination with other pesticides (such as fungicides, insecticides, herbicides, plant growth regulators), fertilizers, etc., and these are mixed with Commonly used pesticides or fertilizers disclosed in the art.

In order to enhance the use effect, the composition of the present invention can be processed into a preparation of various dosage forms with a fertilizer, or co-administered or mixed with a fertilizer. Suitable fertilizers include: inorganic fertilizers or organic fertilizers, such as one or more of a large number of elements containing nitrogen, phosphorus, potassium, etc., or containing copper, iron, manganese, zinc, boron, calcium, magnesium, sulfur, etc. One or more trace elements in the medium or a mixture of at least one of a fertilizer such as humic acid, amino acid, and chitosan.

The composition of the present invention can be made into a pesticide-acceptable dosage form from the active ingredient and the pesticide adjuvant.

In the composition of the present invention, the active ingredient may be present in the composition in an amount of from 0.5 to 85%, preferably from 0.85 to 50% by mass.

The above composition may specifically comprise an agrochemical auxiliary, such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant, etc., during the application process. Mix commonly used auxiliaries.

Suitable auxiliaries may be solid or liquid, they are usually materials commonly used in the processing of dosage forms, such as natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickeners, binders or fertilizers. .

The method of application of the composition of the invention comprises the use of the composition of the invention for aerial parts of plants, in particular leaves Department or leaf surface. You can choose to soak or apply to the surface of the control object. The frequency of application and the amount applied will depend on the growth of the crop.

These compositions may be applied only with the active ingredient or may be mixed with an additive (agrochemical adjuvant).

The composition of the present invention can be prepared into a pesticide-acceptable dosage form such as a liquid, a suspension, a soluble liquid, an oil suspension, a microcapsule, a microemulsion, a wettable powder and the like. Depending on the nature of the compositions and the intended purpose and environmental conditions to which the compositions are to be applied, the compositions may be applied by spraying, misting, dusting, spreading or pouring, and the like.

Microcapsule dosage forms suitable for the present invention include: microcapsule suspension, microcapsule suspension-suspension, microcapsule suspension-water emulsion, etc., characterized in that the inner wall of the capsule (ie, the capsule core) contains the active ingredient amine fresh ester and thiabenzene. Long in accordance with a certain proportion of the mixture, that is, the two are mixed into a microcapsule. The microcapsules are stably dispersed and suspended in a certain concentration to form a microcapsule suspending agent in water as a continuous phase. Alternatively, one of the active ingredients is prepared as a microcapsule suspension, another active ingredient is prepared into an emulsion, and the prepared two components are mixed, stirred, and shaken to obtain a microcapsule suspension-suspension or microcapsule suspension. Agent-water emulsion.

The composition of the present invention can be prepared into various dosage forms by a known method, and the active ingredient and the auxiliary agent, such as a solvent, a solid carrier, and, if necessary, can be uniformly mixed and ground together with the surfactant to prepare a desired preparation. Dosage form.

The above solvent may be selected from aromatic hydrocarbons, preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings. Alkenes or paraffins, alcohols and glycols and their ethers and esters, such as ethanol, ethylene glycol, ethylene glycol monomethyl; ketones, such as cyclohexanone, highly polar solvents such as N-methyl-2 Pyrrolidone, dimethyl sulfoxide or dimethylformamide, and vegetable or vegetable oils such as soybean oil.

The above solid carriers, such as for wettable powders and dispersible agents, are typically natural mineral fillers such as talc, kaolin, montmorillonite or activated clay. In order to manage the physical properties of the composition, it is also possible to add a highly dispersible silicic acid or a highly dispersible adsorbent polymer carrier, such as a particulate adsorbent carrier or a non-adsorbing carrier, and a suitable particulate adsorbent carrier is porous, such as pumice, bentonite or Bentonite; a suitable non-adsorbing carrier such as calcite or sand. In addition, a large amount of pre-granulated materials of inorganic or organic nature can be used as a carrier, in particular dolomite.

Suitable surfactants according to the chemical nature of the active ingredient in the composition of the present invention are lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkaline earth metal or amine salts, alkylarylsulfonates, alkyl groups Sulfates, alkyl sulfonates, fatty alcohol sulphates, fatty acids and sulfated fatty alcohol glycol ethers, as well as condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, naphthalene or naphthalene sulfonic acid with phenol and formaldehyde Condensate, polyoxyethylene octyl phenyl ether, ethoxylated isooctyl phenol, octyl phenol, nonyl phenol, alkyl aryl polyglycol ether, tributyl benzene polyglycol ether, three Stearyl phenyl polyglycol ether, alkyl aryl Polyether alcohol, ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensate, ethoxylated polyoxypropylene, lauric acid polyethylene glycol ether acetal, sorbitol ester, lignin sulfite Waste liquid and methyl cellulose.

Plants of the invention include, but are not limited to, apple or corn.

The two active ingredients in the compositions of the present invention exhibit synergistic effects, the activity of which is more pronounced than the expected sum of activity using a single compound, and the individual activity of a single compound. The other characteristics exhibited by the composition of the present invention are mainly as follows: 1. The composition of the present invention has obvious synergistic effect; 2. The composition of the invention can well regulate crop growth and improve disease resistance. Resistance, promote crop health and increase crop yield.

detailed description

In order to make the objects, technical solutions and advantages of the present invention more comprehensible, the present invention will be further described in detail below with reference to the embodiments. It is understood that the specific embodiments described herein are intended to be illustrative of the invention and are not to be construed as limiting the scope of the invention. Within the scope of protection of the present invention.

The percentages in all formulations in the following examples are by weight (by hundred percent). The processing techniques of the various formulations of the compositions of the present invention are all prior art and may vary depending on the circumstances.

First, the dosage form preparation example

(1) Processing and examples of suspending agents

The active ingredient amine fresh ester and thidiazepine, and the components such as dispersant, wetting agent, thickener and water are uniformly mixed according to the formula, and after being sanded and/or sheared at high speed, semi-finished products are obtained, and analyzed. After the addition of water and evenly filtered, the finished product is obtained.

Example 1: 25.25% thiabendazole-amine fresh ester suspension

Thiabendazole 0.25%, amine fresh ester 25%, xanthan gum 4%, glycerol 2%, kaolin 5%, aluminum silicate magnesium 5%, sodium lignosulfonate 5%, water to 100%.

Example 2: 25.5% thiabendazole-amine fresh ester suspension

Thiabendazole 0.5%, amine fresh ester 25%, bentonite 7%, ethylene glycol 3%, methyl naphthalenesulfonate sodium formaldehyde condensate 5%, water to 100%.

Example 3: 0.875% thiabendazole-amine fresh ester suspension

Thiabendazole 0.5%, amine fresh ester 0.375%, white carbon black 5%, glycerol 6%, sodium benzoate 3%, fatty alcohol polyoxyethylene ether phosphate 5%, water to 100%.

(2) Processing and examples of microcapsules

A mixture of the active ingredient thiabendazole and amine fresh ester in a certain ratio, that is, a mixture of the two to form a microcapsule. The microcapsules are stably dispersed and suspended in a certain concentration to form a microcapsule suspending agent in water as a continuous phase. Or put it One active ingredient is prepared into a microcapsule suspension agent, and another active ingredient is prepared into an emulsion, and the prepared two components are mixed, stirred, and shaken to obtain a microcapsule suspension-suspension or microcapsule suspension agent- Water emulsion.

Example 4: 16.2% thiabendazole-amine fresh ester microcapsule suspension

Thiabendazole 0.2%, amine fresh ester 16%, turpentine vegetable oil 12%, lactic acid glyceride 4%, emulsifier polyoxyethylene castor oil 3%, stabilizer triphenyl phosphite 3.5%, toluene diisocyanate 15%, acrylic acid - 5% acrylate copolymer, 3% dipropylene glycol, 1% preservative sodium benzoate, 2.1% thickener xanthan gum, water up to 100%.

Example 5: 6.2% thiabendazole-amine fresh ester microcapsule suspension-suspending agent

Thiabendazole 0.2%, amine fresh ester 6%, methyl ester coconut oil 15%, polyoxyethylene monopalmitate 5%, BHT 5%, attractant amino acid 2%, sodium benzoate 5%, ethylene glycol 5%, acetic acid 4% ethylene emulsion, 2% xanthan gum, water to 100%.

Example 6: 1.8% thiabendazole-amine fresh ester microcapsule suspension-water emulsion

Thiablon 1%, amine fresh ester 0.8%, gelatin 15%, ethanol 4%, ethylene diamine 5%, methyl naphthalene sulfonate formaldehyde condensate 5%, water to 100%.

(III) Processing and examples of soluble powders

The active ingredient thiabendazole and the amine fresh ester are placed in a kettle according to a certain proportion of the mixture, the surfactant, the auxiliary agent and the filler, and the mixture is thoroughly stirred to obtain a soluble powder.

Example 7: 19.65% thiabendazole-amine fresh ester soluble powder

Thiabendron 0.15%, amine fresh ester 19.5%, sodium alkylbenzene sulfonate 5%, kaolin supplement to 100%.

Example 8: 30.5% thiabendazole-amine fresh ester soluble powder

Thiabendazole 0.5%, amine fresh ester 30%, alkylphenol polyoxyethylene ether polyoxypropylene ether 2%, bentonite to 100%

Example 9: 2% thiabendazole-amine fresh ester soluble powder

Thiabendron 1%, amine fresh ester 1%, benzyl dimethylphenol ethoxylate 4%, ammonium sulfate salt to 100%.

(4) Processing and examples of water agents

The active ingredient and the auxiliary agent are added to the reaction kettle, and the balance is made up with water, and the mixture is uniformly stirred to obtain a thiabendazole-amine fresh ester aqueous solution.

Example 10: 28.2% thiabendazole-amine fresh ester water agent

Mix thiazolone 0.2%, dimethyl sulfoxide 5%, ethanol 5%, stir for 20 minutes, add amine fresh ester 28%, stir for 30 minutes until the amine ester is completely dissolved; add 8% alkyl alcohol sulfate Sodium, the balance is made up with water.

Example 11: 10.5% thiabendazole-amine fresh ester water agent

Add 0.5% of thiabendazole and 8% of ethanol to the reaction kettle, stir for 20 minutes; add 10% of the amine fresh ester, stir for 30 minutes until the amine ester is completely dissolved; add 10% fatty alcohol polyoxyethylene ether, The amount of water is used to make up.

Example 12: 0.8% thiabendazole-amine fresh ester water agent

Add thiabendazole 0.5% and ethanol 5% to the reaction kettle, stir for 20 minutes; add 0.3% of the amine fresh ester, stir for 30 minutes until the amine fresh ester is completely dissolved; add 5% fatty alcohol ethoxylate, the balance with water Make up.

(5) Processing and examples of water emulsion

The active ingredient amine fresh ester and thibenone, and the components such as a solvent, an emulsifier, a dispersing agent, an antifreezing agent and water are mixed in a ratio of the formulation in a reaction kettle, and fully stirred to obtain an aqueous emulsion.

Example 13: 15.125% thiabendazole-amine fresh ester water emulsion

Thiablon 0.125%, amine fresh ester 15%, sodium dodecylbenzene sulfonate 10%, toluene 10%, polyvinyl alcohol 5%, glycerol 5%, silicone defoamer 1%, water complement To 100%.

Example 14: 8.2% thiabendazole-amine fresh ester water emulsion

Thiabendazole 0.2%, amine fresh ester 8%, xylene 10%, polyvinyl alcohol 5%, glycerol 5%, silicone defoamer 1%, water to 100%.

Example 15: 11% thiabendazole-amine fresh ester water emulsion

Thiabendron 1%, amine fresh ester 10%, sodium dodecylbenzene sulfonate 10%, methanol 10%, polyvinyl alcohol 5%, glycerol 5%, silicone defoamer 1%, water complement To 100%.

Example 16: 0.85% thiabendazole-amine fresh ester water emulsion

Thiabendazole 0.5%, amine fresh ester 0.35%, alkylphenol ethoxylate 10%, toluene 10%, glycerol 5%, silicone defoamer 1%, water to 100%.

Second, the efficacy test

(1) Bioassay examples

1. The comprehensive determination test of apple growth regulation by thiablon and DA-6

The thidiazepine and DA-6 were diluted with acetone at a certain concentration, and the crops were sprayed with stems and leaves. The effects of various concentrations on the growth of apple fruit were measured in the garden, including the transverse diameter, longitudinal diameter, single fruit weight and disease resistance of apple. Comprehensive evaluation of the situation, fruit quality, and yield.

Horizontal diameter control rate = (clear water control transverse diameter - transverse diameter after treatment) / clear water control transverse diameter * 100%

Vertical diameter increase rate = (clear water control longitudinal diameter - longitudinal diameter after treatment) / clear water control longitudinal diameter * 100%

Preventive effect = (incidence index of clear water control - incidence index after treatment) / incidence index of clear water control * 100%

Single fruit weight increase rate = (single fruit weight of clear water control - single fruit weight after treatment) / single fruit weight of clear water control *100%

Per mu yield increase rate = (mu yield of clear water control - yield per mu after treatment) / mu yield of clear water control * 100%

Table 1. Summary of the comprehensive determination of the growth regulation of thiabendazole and amine fresh esters

Note: The "amine" in the table is the abbreviation of "amine fresh ester" and the "thio" is the abbreviation of "thiablon". Application period: In the early stage of the initial flowering stage, apple anthracnose did not occur in the apple tree at this stage. The application frequency: 3 times, the application interval is 7-10 days; the application method: stem and leaf spray; the investigation period: the initial stage of apple expansion; in this experiment, the transverse diameter, the longitudinal diameter, the incidence index, the single fruit weight and other indicators are The average of each treatment.

Through experiments, the inventors found that there is a good synergistic effect between thiabendazole and amine fresh ester. The combination of thidiazepine and amine fresh ester in different ratios, relative to thiabendone, amine fresh ester single agent, and clear water Control, the growth regulation effect of apple is obvious, mainly manifested in: 1. The invention can effectively increase the transverse diameter and longitudinal diameter of apple fruit, which can increase the activity of plant peroxidase and nitrate reductase and increase the content of chlorophyll. Photosynthetic speed, which promotes the division and elongation of plant cells, Thereby improving the quality of apple; 2, thiabendone has a certain anti-disease and anti-reverse effect on plant growth when used as a single agent, and amine-fresh ester is a highly bioactive compound, which has certain immunity to crop diseases, amine The co-administration between fresh ester and thiabendone has a good synergistic effect. It can be seen from the above analysis that the synergistic effect between thifenol and amine fresh ester on the prevention of apple anthracnose is compared with single agent and water control. Good preventive effect; 3, due to the synergistic effect of thiabendazole and amine fresh ester in apple expansion period, promotes the nutrient conduction, disease resistance and resistance of apple. In the mature stage of apple, the single fruit weight of apple and the yield per unit of mu have Significant lifting effect; 4, when the ratio of amine fresh ester to thidiazepine in the ratio (0.7 ~ 140): 1, the synergistic effect of the two synergistic effects is obvious, when the ratio of amine fresh ester to thi Pixabay Below 0.7, the synergistic effect of the two is not obvious.

(2) Field efficacy test

1. Field comprehensive experiment of blending thidiazepine with amine fresh ester to adjust the growth and disease resistance of maize crops

During the application period: the early stage of corn tasseling is prone to diseases such as small spot disease.

The number of applications: 2 times. Spraying was carried out using the formulation examples of the present invention, three replicates, and the results were averaged.

Table 2 Field comprehensive experiment of thiazolone and amine fresh ester mixed with corn to regulate growth

The experimental data from Table 2 shows that the product of the present invention can be effectively adjusted to the healthy growth of corn during the male tasseling period. When the ratio of amine fresh ester to thidiazepine is between 0.7 and 140:1, the main performances are as follows: 1. The weight of corn kernel can be significantly increased; 2. The corn plant can be dwarfed, and the corn control can be effectively controlled. To prevent corn from lodging; 3, thiabendazole has a certain promoting effect on the growth of corn, and amine fresh ester has certain resistance to disease and stress, and it has certain synergistic effect after mixing; 4 The composition of the present invention has a significant effect on the unit yield of corn; 5. Example 12 (0.8% thiabendazole-amine fresh ester water), ie, the amine fresh ester: the ratio of thidiazepine 0.3:0.5 The synergistic effect was not significant relative to the single dose control and other examples.

Claims

A synergistic plant growth regulator composition, characterized in that the composition comprises two active components A and B, wherein active component A is thiabendazole and active component B is amine fresh ester, active The weight ratio of component A to active component B is from 1:0.7 to 140.
The composition according to claim 1, wherein the weight ratio of the active component A to the active component B is from 1:0.75 to 130.
The composition according to claim 1, wherein the weight ratio of the active component A to the active component B is from 1:0.8 to 120.
The composition according to claim 1, characterized in that the composition is made into a pesticide-acceptable dosage form from the active ingredient and the adjuvant.
The composition according to claim 4, characterized in that the active ingredient is present in the composition in an amount of from 0.5 to 85% by mass.
The composition according to claim 5, characterized in that the active ingredient is present in the composition in an amount of from 0.85 to 50% by mass.
The composition according to claim 4, characterized in that the dosage form is a liquid, a suspension, a solution or a microcapsule.
The composition according to claim 4, characterized in that the adjuvant is selected from one of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer or Several.
Use of the pesticidal composition according to any one of claims 1 to 8 for promoting or regulating plant growth in the agricultural field.
Use according to claim 9, characterized in that the plant is selected from the group consisting of apple, rice or corn.