WO2017138053A1

WO2017138053A1 - Deodorant

Info

Publication number: WO2017138053A1
Application number: PCT/JP2016/005057
Authority: WO
Inventors: 亮介川口; 保夫芝; 孝弘永安
Original assignee: パナソニックＩｐマネジメント株式会社
Priority date: 2016-02-10
Filing date: 2016-12-05
Publication date: 2017-08-17
Also published as: CN108601856A; TWI624283B; EP3415169A4; EP3415169A1; JP2017140236A; TW201728343A; US20190030199A1

Abstract

This deodorant contains (A) zinc oxide, (B) an organic acid, (C) an aqueous solvent and (D) an amphoteric surfactant having either a carboxylate group or a carboxy group.

Description

Deodorants

The present invention relates to a deodorant.

Conventionally, deodorizers have been used to reduce various odors that occur in daily life, for example, bad odor caused by nitrogen compounds, sulfur compounds, lower fatty acids, aldehydes, and the like. In recent years, with the improvement of the living environment, indoor airtightness has increased, and awareness of odors caused by chemical substances released from building materials has improved, and therefore further odor reduction measures have been required for deodorants. ing.

Also, deodorants may come into contact with the human body during use, and are discarded after use, so it is desirable that they have low toxicity.

Therefore, Japanese Published Patent Publication No. JP2001-190344A (hereinafter referred to as prior art document) proposes a deodorant that uses zinc oxide and amino acids as deodorant components and blends these in water as a solvent. Has been. This deodorant is a solubilized zinc oxide that is sparingly soluble in water using an amino acid as a solubilizer.

However, the deodorizers of the above-mentioned prior art documents have insufficient solubility in water of zinc oxide, so that the transparency of the liquid is not good, or zinc oxide is precipitated and floats and precipitates are generated. There was a case. For this reason, there is a concern that a good appearance cannot be obtained and the commercial value is impaired, and there are restrictions on use.

The present invention has been made in view of the circumstances as described above, and is a deodorant having low toxicity and having high liquid transparency and capable of suppressing the generation of suspended matters and precipitates. It is an issue to provide.

In order to solve the above problems, the deodorizer of the present invention comprises A) zinc oxide, (B) an organic acid, and (C) an aqueous solvent, and (D) a carboxylate group or a carboxy group. And an amphoteric surfactant having either one of them.

According to the deodorant of the present invention, it is a deodorant with low toxicity, the liquid is highly transparent, and it is possible to suppress the occurrence of suspended matters and precipitation.

Hereinafter, an embodiment of the present invention will be described.

The deodorant of this embodiment is an amphoteric interface having (A) zinc oxide, (B) an organic acid, (C) an aqueous solvent, and (D) a carboxylate group or a carboxy group. And an activator.
The amphoteric surfactant (D) has either a carboxylate group or a carboxy group, and even if it is blended alone without blending an organic acid (B) such as an amino acid, zinc oxide (A ) Is not dissolved in an aqueous solvent (C) such as water. However, when used in combination with the organic acid (B), which is a solubilizing agent for zinc oxide (A), it acts as a solubilizing agent that increases the solubility of zinc oxide (A) in the aqueous solvent (C). Therefore, by adding such an amphoteric surfactant (D), the solubility of zinc oxide (A) is increased, thereby improving the transparency of the liquid and suppressing the occurrence of suspended matters and precipitation. it can.

Since the amphoteric surfactant (D) is further less toxic, it may come into contact with the human body, and the safety of the deodorant discarded after use can be increased.

The amphoteric surfactant (D) is not particularly limited, and examples thereof include betaine type amphoteric surfactants and glycine type amphoteric surfactants. These may be used alone or in combination of two or more.

Examples of betaine-type amphoteric surfactants include alkyl betaines. Examples of alkylbetaines include lauryl dimethylaminoacetic acid betaine, stearyldimethylaminoacetic acid betaine, and the like. These may be used alone or in combination of two or more.

Examples of the glycine-type amphoteric surfactant include those represented by the following general formulas (1) and (2). These may be used alone or in combination of two or more.
R- (NHCH ₂ CH ₂ ) ₂ NHCH ₂ COOM (1)
(R-NHCH ₂ CH ₂ ) ₂ NCH ₂ COOM (2)
(In the formula, R represents an alkyl or alkenyl group having 3 to 20 carbon atoms, and M represents a hydrogen atom, an alkali metal, an amine, or an alkanolamine.)
Examples of the glycine-type amphoteric surfactants represented by the above general formulas (1) and (2) include sodium lauryl diaminoethyl glycine (product name: Levon S manufactured by Sanyo Chemical Industries), alkyl polyaminoethyl glycine hydrochloride (product) Name: Levon U Sanyo Chemical Industries).

The amphoteric surfactant (D) preferably has the same number of monovalent cations and monovalent anions in the molecule. By using the amphoteric surfactant (D) that satisfies such conditions, the transparency of the liquid can be further increased, and the occurrence of suspended matters and precipitation can be further suppressed. Examples of such amphoteric surfactant (D) include betaine-type amphoteric surfactants.

As the amphoteric surfactant (D), lauryldimethylaminoacetic acid betaine is preferable in view of further improving the transparency of the liquid and further suppressing the generation of suspended matters and precipitation.

The blending amount of the amphoteric surfactant (D) having a carboxylate group or a carboxy group in the deodorant of the present embodiment is improved in the transparency of the liquid and can suppress the occurrence of suspended matters and precipitation. Is considered to be within the range of 0.2 to 2% by mass.

Although it does not specifically limit as zinc oxide (A) mix | blended with the deodorizer of this embodiment, For example, the powdery thing used as a cosmetics raw material or a pharmaceutical raw material is mentioned, for example, fine Zinc oxide or the like can be used.

The organic acid (B) blended in the deodorant of this embodiment acts as a deodorant component and as a solubilizer for zinc oxide (A). Examples of the organic acid (B) include amino acids and pyrrolidone carboxylic acids. These may be used alone or in combination of two or more. Among these, amino acids are preferred in view of deodorizing action, zinc oxide (A) solubility, and liquid safety. Examples of amino acids include glycine, alanine, phenylalanine, glutamate, proline, betaine, sarcosine and the like. These may be used alone or in combination of two or more. Any isomers of D-form, L-form, and racemate can be used. Among these amino acids, glycine, alanine, and sarcosine are preferable.

The blending amount of the organic acid (B) in the deodorant of this embodiment is a mass ratio with respect to zinc oxide (A) (zinc oxide (A): organic), considering the solubility and deodorizing action of zinc oxide (A). The acid (B)) is preferably in the range of 1: 3 to 1:40.

The aqueous solvent (C) blended in the deodorant of this embodiment is a solvent such as zinc oxide (A), organic acid (B), and amphoteric surfactant (D). Examples of the aqueous solvent (C) include water such as ion-exchanged water and tap water, water such as a water-alcohol solvent, a water-glycol solvent, a water-glycol monoether solvent, and a water-soluble organic solvent. A mixed solvent etc. are mentioned. Among these, water is preferable in consideration of safety and economy.

The total amount of zinc oxide (A) and organic acid (B) with respect to the aqueous solvent (C) is in the range of 0.01 to 20% by mass in consideration of the deodorizing action and the suppression of the generation of suspended matters and precipitation. Is preferable, and the range of 0.1 to 10% by mass is more preferable.

The deodorizer of this embodiment preferably further contains an organic acid metal salt (E). When the organic acid metal salt (E) is blended, the transparency of the liquid can be further increased. This is considered to be because the stabilizing effect on zinc oxide (A) due to complex formation is further enhanced. Even if an inorganic metal salt is blended, the effect of improving the transparency of such a liquid cannot be obtained. The organic acid metal salt (E) is not particularly limited, and examples thereof include sodium dehydroacetate, trisodium citrate, and potassium sorbate. These may be used alone or in combination of two or more.

In the deodorant of this embodiment, an additive can be appropriately added within a range that does not inhibit the effect. Examples of the additive include preservatives, essential oils, fragrances, and ultraviolet absorbers. These may be used alone or in combination of two or more.

The deodorant of this embodiment can be prepared, for example, by the following method. A deodorant is prepared by preparing a suspension of zinc oxide (A) and an aqueous solution of organic acid (B) in advance, and mixing them in a predetermined combination ratio. Alternatively, zinc oxide (A) fine particles and organic acid (B) are mixed in a predetermined ratio, and then the mixture is dissolved in an aqueous solvent (C) to prepare a deodorant. Alternatively, a deodorant is prepared by adding and mixing fine particles of zinc oxide (A) at a predetermined ratio to the organic acid (B) in an aqueous solution of the organic acid (B).

In addition to being used as an aqueous solution, the deodorant of the present embodiment can be used in various forms such as a spray form, a gel form using a gel base material, an aerosol form, etc., and a form suitable for the use situation can be selected. it can.

The deodorant of the present embodiment includes, for example, nitrogen compounds such as ammonia and amines, sulfur compounds such as hydrogen sulfide and methyl mercaptan, lower fatty acids such as acetic acid, isovaleric acid and caproic acid, formaldehyde, acetaldehyde and the like. It can be used to remove malodorous gases such as aldehydes.

According to the deodorant of this embodiment described above, in addition to zinc oxide (A), organic acid (B), and aqueous solvent (C), either one of a carboxylate group or a carboxy group is added. The amphoteric surfactant (D) is further contained. Thereby, while being a deodorant with low toxicity, the transparency of a liquid is high and generation | occurrence | production of a suspended | floating matter and precipitation can be suppressed.
The present invention is not limited to the above embodiment.

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples. However, the present invention is not limited to these examples. In addition, the compounding amount of each component shown in Tables 1 to 3 indicates mass%. 1. Evaluation of Deodorant Incorporating Various Surfactants With the formulation shown in Table 1, each component was added to ion-exchanged water of an aqueous solvent (C) at room temperature and stirred, and a deodorant was prepared without performing filtration. Zinc oxide (A), organic acid (B), and preservative are blended in the deodorant, and in Example 1, lauryldimethylaminoacetic acid betaine, which is an amphoteric surfactant having a carboxylate group, is used as the surfactant. Was formulated. In Example 2, sodium lauryldiaminoethylglycine, which is an amphoteric surfactant having a carboxy group, was added as a surfactant. In Comparative Example 2, an anionic surfactant sodium polyoxyethylene alkyl ether sulfate was added as a surfactant. In Comparative Example 3, a cationic surfactant, cetylpyridium chloride, was blended as a surfactant. In Comparative Example 4, a nonionic surfactant polyoxyalkyl decyl ether was blended as a surfactant. Comparative Example 1 was a basic formulation that did not contain a surfactant.

The following evaluation was performed about the obtained deodorizer.
(Liquid appearance)
The above components were added to ion-exchanged water, and the appearance of the liquid after standing for 30 minutes after stirring was evaluated according to the following criteria. In this evaluation, “excellent” and “good” were judged as good, and the others (fair, bad) were judged as bad.
Excellent: colorless and transparent with no floating or sediment
good: Light blue white translucent and no suspended matter / precipitation
fair: no precipitation, float
bad: Cloudy or precipitated (surfactant toxicity)
Table 1 shows the oral LD50 catalog values for the surfactants used.
(Deodorant)
The deodorizing rate of hydrogen sulfide was measured for a diluted solution obtained by diluting the deodorant stock solution 200 times with ion-exchanged water.

As hydrogen sulfide, a high concentration gas (0.15 ml) was used, and the deodorization rate was measured by the following method.

After the nonwoven fabric was put into the flask, a deodorant diluted solution was supplied to the nonwoven fabric. Next, hydrogen sulfide was supplied to the flask, and after standing for 60 minutes, the gas in the flask was sucked with a gas detector tube, and the concentration of hydrogen sulfide was measured. In addition, the deodorizing rate was calculated | required compared with the density | concentration of the hydrogen sulfide in the same blank flask except not supplying the dilution liquid of a deodorizer.

From the above measurement results of the deodorization rate of hydrogen sulfide, the case where the deodorization rate of hydrogen sulfide was 90% or more was evaluated as “good”.

Table 1 shows the results of the above measurements and evaluations.

* 1 Fine zinc oxide (manufactured by Sakai Chemical Industry)
* 2 Glycine M (manufactured by Fuso Chemical Industries)
* 3 Sanyo Kasei Kogyo * 4 Sanyo Kasei Kogyo * 5 Kao * 6 Daiichi Kogyo Seiyaku * 7 San Nopco From Table 1, Examples 1 and 2 containing amphoteric surfactants, cationic surfactants The comparative example 3 and the comparative example 4 which mix | blended the nonionic surfactant were favorable in the external appearance of the liquid compared with the comparative example 1 of the basic mixing | blending which does not mix | blend surfactant. Among them, Example 1 in which amphoteric surfactant lauryldimethylaminoacetic acid betaine was blended and Comparative Example 3 in which cationic surfactant cetylpyridium chloride was blended were colorless and transparent, had no suspended matter, and had the best results. there were. The deodorizing properties of Examples 1 and 2 and Comparative Examples 3 to 4 were all good compared to the basic composition of Comparative Example 1 in which no surfactant was blended. In Comparative Example 2 in which the anionic surfactant was blended, the liquid became cloudy, and the transparency of the liquid was lower than that in Comparative Example 1 in which the basic blend was not blended.

Regarding the toxicity of the surfactants, Examples 1 and 2, which are amphoteric surfactants, had low oral LD50 values exceeding 2500 mg. On the other hand, Comparative Example 2 which is an anionic surfactant, Comparative Example 3 which is a cationic surfactant, and Comparative Example 4 which is a nonionic surfactant are highly toxic when the oral LD50 is less than 2000 mg. It was.

From the above results, the deodorant of Example 1 blended with amphoteric surfactant lauryldimethylaminoacetic acid betaine was the best considering the overall appearance, toxicity and deodorant of the liquid. The deodorant of Example 2 blended with the amphoteric surfactant sodium lauryldiaminoethylglycine is slightly inferior in liquid appearance as compared to Example 1, but the surface activity and toxicity are comprehensively considered. An improvement effect was recognized in the appearance of the liquid without lowering the toxicity as compared with Comparative Example 1 having a basic composition in which no agent was blended.
2. Evaluation of deodorant mixed with various amphoteric surfactants Examples 1 and 2 blended with amphoteric surfactants were all good in liquid appearance, surfactant toxicity, and deodorant properties. Therefore, the relationship between the type of amphoteric surfactant and the appearance of the liquid was further evaluated.

Each component was added to the ion-exchanged water of the aqueous solvent (C) with the formulation shown in Table 2 and stirred at room temperature, and a deodorant was produced without performing filtration. Zinc oxide (A), organic acid (B), and preservative were blended in the deodorant, and in Example 1, lauryldimethylaminoacetic acid betaine was blended as an amphoteric surfactant having a carboxylate group. In Example 2, sodium lauryl diaminoethylglycine was blended as an amphoteric surfactant having a carboxy group. In Comparative Example 5, lauramidopropylhydroxysultain was blended as an amphoteric surfactant having neither a carboxylate group nor a carboxy group. Comparative Example 1 was a basic formulation that did not contain a surfactant.

The following evaluation was performed about the obtained deodorizer.
(Liquid appearance)
The above components were added to ion-exchanged water, and the appearance of the liquid after standing for 30 minutes after stirring was evaluated according to the following criteria. In this evaluation, “excellent” and “good” were judged as good, and the others (fair, bad) were judged as bad.
Excellent: colorless and transparent with no floating or sediment
good: Light blue white translucent and no suspended matter / precipitation
fair: no precipitation, float
bad: cloudiness or precipitation present The results of the above evaluation are shown in Table 2.

* 1 Fine zinc oxide (manufactured by Sakai Chemical Industry)
* 2 Glycine M (manufactured by Fuso Chemical Industries)
* 3 Sanyo Kasei Kogyo * 4 Sanyo Kasei Kogyo * 5 Kawaken Fine Chemical * 6 San Nopco From Table 2, Example 1 containing lauryldimethylaminoacetic acid betaine having a carboxylate group as an amphoteric surfactant is shown in Table 1 Similar to 1, it was colorless and transparent and had no suspended matter, and the best result was obtained. Example 2 in which sodium lauryldiaminoethylglycine having a carboxy group as an amphoteric surfactant was blended was slightly inferior to that in Example 1, but there was no white suspended matter, and no basic blend was added. As compared with Comparative Example 1, the effect of improving the liquid appearance was recognized. On the other hand, Comparative Example 5 in which lauramidopropylhydroxysultain was added as an amphoteric surfactant was colorless and transparent, but had white floating matters and the appearance of the liquid was lowered.

From the above results, among the amphoteric surfactants, the amphoteric surfactant (D) having a carboxylate group (—COO ⁻ ) or carboxy group which is a weak acid as in Examples 1 and 2 has an effect of improving the appearance of the liquid. Was recognized. Among them, when the amphoteric surfactant has the same number of monovalent cations (N ⁺ ) and monovalent anions (COO ⁻ ) in the molecule as in Example 1, the amphoteric as in Example 2 The appearance of the liquid was particularly good as compared with the surfactants having different valences. On the other hand, those having a sulfo group (—SO ₃ ⁻ ), which is a strong acid as in Comparative Example 5, had white floating matters and the liquid appearance was not satisfactory.
3. Compounding amount of amphoteric surfactant From the above results, the appearance of the liquid, the toxicity of the surfactant, and the deodorizing property were all good. The blending amount was changed and the appearance of the liquid was evaluated.

Each component was added to the ion-exchanged water of the aqueous solvent (C) with the formulation shown in Table 3 and stirred at room temperature, and a deodorant was produced without performing filtration. About the obtained deodorizer, each component was added and the external appearance of the liquid 30 minutes after stirring was evaluated. The case of colorless and transparent and no precipitation was evaluated as “excellent”.

The results of the above evaluation are shown in Table 3.

* 1 Fine zinc oxide (manufactured by Sakai Chemical Industry)
* 2 Glycine M (manufactured by Fuso Chemical Industries)
* 3 Sanyo Kasei Kogyo * 4 San Nopco From Table 3, Examples 3 and 4 containing 0.2 to 2% by mass of lauryldimethylaminoacetic acid betaine as an amphoteric surfactant (D) having a carboxylate group or a carboxy group All of Nos. 5 and 6 were colorless and transparent, had no precipitate, and had good liquid appearance.

Claims

(A) zinc oxide;
(B) an organic acid;
(C) an aqueous solvent;
(D) an amphoteric surfactant having either one of a carboxylate group or a carboxy group;
Deodorant characterized by containing.
The deodorant according to claim 1, wherein the amphoteric surfactant (D) has the same number of monovalent cations and monovalent anions in the molecule.
The deodorant according to claim 1 or 2, wherein the amphoteric surfactant (D) is lauryldimethylaminoacetic acid betaine.