JP6839821B2 - Deodorants - Google Patents

Description

The present disclosure relates to deodorants in general, and more specifically to deodorants containing zinc oxide.

Patent Document 1 discloses an antibacterial deodorant. This antibacterial deodorant contains a zinc compound and an amino acid as active ingredients. Here, the zinc compound is at least one selected from zinc carbonate and zinc oxide. On the other hand, the amino acid is at least one selected from the group of glycine, alanine, phenylalanine, glutamic acid salt and sarcosine. The combined ratio of the zinc compound and the amino acid is in the range of 1: 2 to 1:50 by weight.

JP-A-2006-026156 (paragraph [0032])

The antibacterial deodorant of Patent Document 1 may be used by spraying it on a textile product in the form of an aqueous solution, but in this case, a trace may be generated. The "trace residue" means that after the deodorant adhering to the textile product or the like has dried, a trace of the deodorant remains to the extent that it can be visually confirmed. As described above, the antibacterial deodorant of Patent Document 1 has a good deodorizing effect, and even if there is no undissolved residue of the active ingredient in the form of an aqueous solution, there is a possibility that a trace residue may occur. There is room for improvement.

An object of the present disclosure is to provide a deodorant capable of suppressing undissolved residue and trace residue of an active ingredient while having good deodorizing property.

The deodorant according to one aspect of the present disclosure contains zinc oxide, glycine, threonines, and an aqueous solvent. The threonines include at least one selected from the group consisting of threonine and threonine derivatives.

According to the present disclosure, it is possible to suppress undissolved residue and trace residue of the active ingredient while having good deodorant property.

1. 1. Outline The deodorant according to the present embodiment contains zinc oxide, glycine, threonines, and an aqueous solvent. The active ingredients of the deodorant are zinc oxide, glycine and threonines. Threonines include at least one selected from the group consisting of threonine and threonine derivatives. The deodorant is in the form of an aqueous solution.

When the active ingredients of the deodorant are zinc oxide and glycine, they have good deodorizing properties and can suppress the undissolved residue of the active ingredients. Here, when threonines are added as an active ingredient, it is possible to suppress the trace residue while maintaining good deodorant property and solubility.

That is, the deodorant according to the present embodiment can suppress undissolved residue and trace residue of the active ingredient while having good deodorizing property.

2. 2. Details The deodorant contains zinc oxide, glycine, threonines, and an aqueous solvent. The active ingredients of the deodorant are zinc oxide, glycine and threonines. Depending on these active ingredients, sulfur compounds such as hydrogen sulfide and methyl mercaptan, nitrogen compounds such as ammonia and amines, lower fatty acids such as acetic acid, isovaleric acid and caproic acid, and aldehydes such as formaldehyde and acetaldehyde can be used. Malodorous gas can be removed. That is, the deodorant has good deodorizing properties against these malodorous gases.

The deodorant is in the form of an aqueous solution. Unless otherwise specified, in the following, the term deodorant means a stock solution. Glycine and threonines are easily soluble in aqueous solvents (particularly water). Zinc oxide is sparingly soluble in aqueous solvents, but the coexistence of glycine and threonines improves the solubility of zinc oxide. That is, it is possible to suppress the undissolved residue of the active ingredient of the deodorant.

Threonines include at least one selected from the group consisting of threonine and threonine derivatives. Here, a threonine derivative means a compound produced by a change in a small portion of threonine in the molecule. Threonine derivatives also include substitutions in which the hydrogen atom in the threonine molecule is replaced by another atom or atomic group. Specific examples of threonine derivatives include L-threonine (L-threonine: Protein Chemical Co., Ltd.), DL-threonine, D-threonine, L-allothreonine, N- (tert-butoxycarbonyl) -D-threonine methyl, Examples thereof include N-[(9H-fluoren-9-ylmethoxy) carbonyl] -O-tert-butyl-D-threonine and glycyl-L-threonine. Threonines are effective in suppressing the traces of deodorants. That is, even if the deodorant is attached to a textile product or the like and dried, and then the deodorant adhered portion is observed, it is difficult to visually confirm the trace. The object to which the deodorant adheres is not limited to textile products.

The mass ratio of glycine to threonines is preferably in the range of 1: 2 to 2: 1, more preferably in the range of 1.25: 1 to 1: 1.12. In other words, the value of the mass ratio of glycine / threonine is preferably in the range of 0.5 or more and 2 or less, and more preferably in the range of 0.89 or more and 1.25 or less. When the value of the mass ratio of glycine / threonine is 0.5 or more, the amount of glycine does not become too small, and the solubility of the active ingredient can be further improved. When the value of the mass ratio of glycine / threonine is 2 or less, the amount of glycine does not become too large, and the trace of the deodorant can be further suppressed. That is, when the mass ratio of glycine and threonines is within the above range, it is possible to further suppress the undissolved residue and the trace residue of the active ingredient.

The mass ratio of zinc oxide to threonines is preferably in the range of 1: 1.5 to 1: 4, and more preferably in the range of 1: 1.5 to 1: 3. In other words, the value of the mass ratio of zinc oxide / threonines is preferably in the range of 0.25 or more and 0.67 or less, and more preferably in the range of 0.33 or more and 0.67 or less. When the value of the mass ratio of zinc oxide / threonines is 0.25 or more, the amount of zinc oxide does not become too small, and the reduction of the deodorizing effect due to zinc oxide can be suppressed. When the value of the mass ratio of zinc oxide / threonines is 0.67 or less, the amount of zinc oxide does not become too large, and the solubility of the active ingredient can be further improved. That is, when the mass ratio of zinc oxide and threonines is within the above range, the reduction of the deodorizing effect due to zinc oxide can be suppressed, and the undissolved residue of the active ingredient can be further suppressed.

Specific examples of the aqueous solvent include water and a mixed solvent of water and alcohol. Water includes tap water and purified water. Purified water includes ion-exchanged water, distilled water, pure water, ultrapure water, and RO membrane water. Alcohols include ethanol, methanol and isopropyl alcohol.

The content of the active ingredient (that is, the total content of zinc oxide, glycine and threonine) is preferably 2.5% by mass or more and 8.5% by mass with respect to the total mass of the deodorant (in this case, the undiluted solution). It is in the range of% or less, and more preferably in the range of 4.0% by mass or more and 7.0% by mass or less. The undiluted solution of the deodorant may be used as it is, or may be diluted with an aqueous solvent up to 250 times before use. When the stock solution of the deodorant is diluted 250 times, the lower limit of the preferable content of the active ingredient is 0.010% by mass, and the lower limit of the more preferable content of the active ingredient is 0.016% by mass. Even if diluted, it still has a deodorizing effect, and the undissolved residue and trace residue of the active ingredient are further suppressed.

The deodorant preferably further contains an amphoteric surfactant. Specific examples of amphoteric surfactants include lauryl betaine (Levon LD-36: Sanyo Kasei Kogyo Co., Ltd.), lauramide propyl betaine, myristamide propyl betaine, sodium cocoamphoacetate, sodium lauroamphoacetate, sodium lauramide propionate, and cocamide. Sodium propionate, stearyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyeter imidazolium betaine, sodium β-alkylaminopropionate, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, 2, Included are -alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, sodium laurylaminodipropionate, palm nuclear fatty acid amide propyl betaine and lauramide propyl hydroxysultaine. By further containing such an amphoteric surfactant in the deodorant, it is possible to further suppress the undissolved residue of the active ingredient.

When the deodorant further contains an amphoteric surfactant, the content of the amphoteric surfactant preferably exceeds 0.08% by mass with respect to the total mass of the deodorant (in this case, the undiluted solution). It is in the range of less than 22% by mass, more preferably in the range of 0.1% by mass or more and 19% by mass or less. When the content of the amphoteric surfactant exceeds 0.08% by mass, the undissolved residue of the active ingredient can be further suppressed, and the transparency of the deodorant can be ensured. When the content of the amphoteric surfactant is less than 22% by mass, the trace residue of the deodorant can be further suppressed. That is, when the content of the amphoteric surfactant is within the above range, it is possible to further suppress the trace residue while ensuring the transparency of the deodorant.

The deodorant can be prepared by blending zinc oxide, glycine, threonines and an aqueous solvent, further blending an amphoteric surfactant if necessary, and stirring the blend.

The deodorant can be used by putting it in a spray container and spraying it in a mist form. Further, the deodorant and the propellant (liquefied gas or compressed gas) may be put in a spray container and sprayed in the form of an aerosol for use. The deodorant can be used by spraying it on an object of concern for odor. Specific examples of the object include textile products, but are not particularly limited.

3. 3. Summary As described above, the deodorant according to the first aspect contains zinc oxide, glycine, threonines, and an aqueous solvent. The threonines include at least one selected from the group consisting of threonine and threonine derivatives.

According to this aspect, it is possible to suppress undissolved residue and trace residue of the active ingredient while having good deodorant property.

The deodorant according to the second aspect has a mass ratio of the glycine to the threonines in the range of 1: 2 to 2: 1 in the first aspect.

According to this aspect, the undissolved residue and the trace residue of the active ingredient can be further suppressed.

The deodorant according to the third aspect has a mass ratio of the zinc oxide to the threonines in the range of 1: 1.5 to 1: 4 in the first or second aspect.

According to this aspect, the reduction of the deodorizing effect due to zinc oxide can be suppressed, and the undissolved residue of the active ingredient can be further suppressed.

The deodorant according to the fourth aspect further contains an amphoteric surfactant in any one of the first to third aspects.

According to this aspect, the undissolved residue of the active ingredient can be further suppressed.

In the fourth aspect, the deodorant according to the fifth aspect has a content of the amphoteric surfactant of more than 0.08% by mass and less than 22% by mass with respect to the total mass of the deodorant. It is within the range.

According to this aspect, it is possible to further suppress the trace residue while ensuring the transparency of the deodorant.

Hereinafter, the present disclosure will be specifically described with reference to Examples, but the present disclosure is not limited to the Examples.

1. 1. Experiment 1
(1) Preparation of deodorant Zinc oxide, glycine, threonine (threonine) and aqueous solvent (ion-exchanged water) are mixed in a glass bottle at the ratio shown in Table 1, and this mixture is stirred for 30 minutes. The deodorant (stock solution) of each Example and Comparative Example was prepared according to the above.

(2) Test (2.1) Undissolved residue The deodorant in the glass bottle after stirring for 30 minutes was observed. Based on this observation result, the undissolved residue was evaluated according to the following criteria.

A: No sediment or suspended matter B: Precipitate is visible at the bottom of the bottle C: Precipitate is laminated on the bottom of the bottle Note that the description such as "AB" is an intermediate evaluation between A and B. It means that the same applies to the following.

(2.2) Deodorant The deodorant was diluted 20-fold with ion-exchanged water to prepare an aqueous deodorant solution (5% by mass). A 5 mL aqueous deodorant solution was injected into the flask with a micropipette. Further, hydrogen sulfide gas was injected into the flask with a syringe so as to have a concentration of 100 ppm / L, the flask was plugged, and the flask was allowed to stand for 5 minutes. Then, the hydrogen sulfide concentration in the flask was measured with a gas detector tube. Based on this measurement result, the deodorant property was evaluated according to the following criteria.

A: Deodorant rate 80% or more B: Deodorant rate 20% or more and less than 80% C: Deodorant rate less than 20%

(2.3) Remaining 10 μL of deodorant (stock solution) was applied to a glass plate (Matsunami Glass Industry Co., Ltd., product number: S9213, product number: S9213, manufactured by Nichiryo Co., Ltd., product number: NichipetEX NPX-100) with a pipette man (Gilson Co., Ltd.). It was attached to the upper surface of a large slide glass). This glass plate was placed in a constant temperature bath set at 105 ° C. and heated for 60 minutes. Then, the glass plate was taken out from the constant temperature bath and the upper surface thereof was observed. Based on this observation result, the trace residue was evaluated according to the following criteria.

A: The trace is transparent B: The trace is translucent C: The trace is white

In Experiment 1, the effect of different combinations of active ingredients was verified.

As is clear from Table 1, in Examples 1-2 to 1-6, all points of undissolved residue, deodorant property and trace residue were good.

On the other hand, in Comparative Example 1-1 containing no threonines, traces were generated. Further, in Comparative Example 1-7 containing no glycine, undissolved residue occurred. Furthermore, in Comparative Example 1-8 containing neither glycine nor threonine, it was poor in all points of undissolved, deodorant and trace residue.

From the above, it was found that the combined use of zinc oxide, glycine and threonine as active ingredients is effective.

2. 2. Experiment 2
(1) Preparation of deodorant Zinc oxide, glycine, threonines (threonine), amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) are mixed in a glass bottle at the ratio shown in Table 2. The deodorant of each Example and Comparative Example was prepared by stirring this formulation for 30 minutes. As for the amphoteric surfactant (lauryl betaine), the concentration of the 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Tests (2.1) Undissolved, deodorant and traces As in Experiment 1, undissolved, deodorant and traces were tested.

(2.2) Transparency The deodorant in the glass bottle after stirring for 30 minutes was observed. Based on this observation result, transparency was evaluated according to the following criteria.

A: Colorless and transparent B: Blue-white to translucent C: Cloudy

In Experiment 2, the effect of using an amphoteric surfactant was verified.

As is clear from Table 2, the combination of zinc oxide, glycine and threonine as active ingredients is effective even when the amphoteric tenside agent is added from the comparison of each example and comparative example. It turned out to be.

Further, from the comparison between each example of Experiment 1 and each example of Experiment 2, it was found that the use of the amphoteric surfactant generally suppressed the undissolved residue.

Furthermore, from the results of Examples 2-2-2-3.5, it was found that it is more effective that the mass ratio of glycine to threonines is in the range of 2: 1 to 19:17. That is, these examples are best in all respects of undissolved residue, deodorant property, trace residue and transparency.

3. 3. Experiment 3
(1) Preparation of deodorant Zinc oxide, glycine, threonines (threonine), alanine, sarcosine, phenylalanine, amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) in a glass bottle at the ratio shown in Table 3. The deodorant of each Example and Comparative Example was prepared by mixing the mixture in and stirring the mixture for 30 minutes. As for the amphoteric surfactant (lauryl betaine), the concentration of the 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Test Similar to Experiment 2, tests of undissolved residue, deodorant property, trace residue and transparency were performed.

In Experiment 3, the effects of the case where the amino acid in the active ingredient was only glycine and the case where the amino acid was glycine and other amino acids were verified. Other amino acids are specifically threonines, alanine, sarcosine and phenylalanine.

As is clear from Table 3, the combination of glycine and threonine was found to be the best from the comparison of each example and comparative example.

4. Experiment 4
(1) Preparation of deodorant Zinc oxide, glycine, threonine (threonine), amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) are mixed in a glass bottle at the ratio shown in Table 4. The deodorant of each example was prepared by stirring this formulation for 30 minutes. As for the amphoteric surfactant (lauryl betaine), the concentration of the 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Test Similar to Experiment 2, tests of undissolved residue, deodorant property, trace residue and transparency were performed.

In Experiment 4, the effect of the difference in the content of the amphoteric surfactant was verified.

As is clear from Table 4, it was found from each example that the content of the amphoteric surfactant is preferably in the range of more than 0.08% by mass and less than 22% by mass.

Claims (2)

It contains zinc oxide, glycine, threonines, an aqueous solvent, and an amphoteric tenside.
The threonines include at least one selected from the group consisting of threonine and threonine derivatives.
The content of amphoteric surfactants Ri der range of less than 22% by weight greater than 0.08 wt%,
Mass ratio of the zinc oxide and the threonine compound is 1: 1.5 to 1: Ru der range of 4,
Deodorants. The mass ratio of the glycine to the threonines is in the range of 1: 2 to 2: 1.
The deodorant according to claim 1.