JP2019141417A - Deodorant - Google Patents

Abstract

To provide a deodorant that can suppress an active ingredient from being undissolved and leaving marks, while having excellent deodorant properties.SOLUTION: A deodorant has zinc oxide, glycine, threonine, and an aqueous solvent. The threonine has at least one selected from the group consisting of threonine and threonine derivatives.SELECTED DRAWING: None

Description

  The present disclosure relates generally to deodorants, and more particularly to deodorants containing zinc oxide.

  Patent Document 1 discloses an antibacterial deodorant. This antibacterial deodorant contains a zinc compound and an amino acid as active ingredients. Here, the zinc compound is at least one selected from zinc carbonate and zinc oxide. On the other hand, the amino acid is at least one selected from the group of glycine, alanine, phenylalanine, glutamate and sarcosine. And the combined ratio of a zinc compound and an amino acid exists in the range of 1: 2-1: 50 by weight ratio.

JP 2006-026156 A (paragraph [0032])

  The antibacterial deodorant of Patent Document 1 may be used by spraying on a textile product in the form of an aqueous solution. In this case, there is a possibility that a trace remains. The remaining trace means that the deodorant remains on the deodorant to the extent that it can be visually confirmed after the deodorant adhered to the fiber product is dried. As described above, the antibacterial deodorant of Patent Document 1 has a good deodorizing effect, and even if there is no undissolved active ingredient in the form of an aqueous solution, there is a possibility that a trace remains. There is room for improvement.

  The objective of this indication is providing the deodorizer which can suppress the undissolved residue and trace residue of an active ingredient, having favorable deodorizing property.

  A deodorant according to one embodiment of the present disclosure contains zinc oxide, glycine, threonines, and an aqueous solvent. The threonine includes at least one selected from the group consisting of threonine and threonine derivatives.

  According to the present disclosure, it is possible to suppress the undissolved residue and traces of the active ingredient while having good deodorizing properties.

1. Outline The deodorant according to the present embodiment contains zinc oxide, glycine, threonines, and an aqueous solvent. The active ingredients of the deodorant are zinc oxide, glycine and threonine. The threonine includes at least one selected from the group consisting of threonine and a threonine derivative. The deodorant is in the form of an aqueous solution.

  When the active ingredients of the deodorant are zinc oxide and glycine, the deodorant has good deodorizing properties and can suppress the remaining undissolved active ingredients. Here, when threonine is added as an active ingredient, traces can be suppressed while maintaining good deodorizing properties and solubility.

  That is, the deodorizer according to the present embodiment can suppress undissolved residues and traces of active ingredients while having good deodorizing properties.

2. Details The deodorant contains zinc oxide, glycine, threonines, and an aqueous solvent. The active ingredients of the deodorant are zinc oxide, glycine and threonine. By these active ingredients, sulfur compounds such as hydrogen sulfide and methyl mercaptan, nitrogen compounds such as ammonia and amines, lower fatty acids such as acetic acid, isovaleric acid and caproic acid, and aldehydes such as formaldehyde and acetaldehyde The malodorous gas can be removed. That is, the deodorant has a good deodorizing property against these malodorous gases.

  The deodorant is in the form of an aqueous solution. Unless otherwise noted, hereinafter, deodorant means stock solution. Glycine and threonines are readily soluble in aqueous solvents (especially water). Zinc oxide is hardly soluble in an aqueous solvent, but the solubility of zinc oxide is improved by the coexistence of glycine and threonines. That is, the remaining undissolved active ingredient of the deodorant can be suppressed.

  The threonine includes at least one selected from the group consisting of threonine and a threonine derivative. Here, the threonine derivative means a compound produced by a change in a small part in the molecule of threonine. The threonine derivative also includes a substitution product in which a hydrogen atom in the molecule of threonine is substituted with another atom or atomic group. Specific examples of the threonine derivative include L-threonine (L-threonine: Protein Chemical Co., Ltd.), DL-allothreonine, D-allothreonine, L-allothreonine, N- (tert-butoxycarbonyl) -D-threonine methyl, N-[(9H-fluoren-9-ylmethoxy) carbonyl] -O-tert-butyl-D-threonine and glycyl-L-threonine. Threonines are effective in suppressing traces of deodorants. That is, even after the deodorant is attached to a fiber product and dried and then the deodorant is adhered, it is difficult to visually confirm the trace. In addition, the adhesion target object of a deodorizer is not limited to a textile product.

  The mass ratio of glycine to threonines is preferably in the range of 1: 2 to 2: 1, more preferably in the range of 1.25: 1 to 1: 1.12. In other words, the value of the mass ratio of glycine / threonine is preferably in the range of 0.5 to 2, more preferably in the range of 0.89 to 1.25. When the value of the mass ratio of glycine / threonine is 0.5 or more, glycine is not decreased too much, and the solubility of the active ingredient can be further improved. When the value of the mass ratio of glycine / threonine is 2 or less, the amount of glycine does not increase excessively, and the trace of the deodorant can be further suppressed. That is, when the mass ratio of glycine and threonine is within the above range, the undissolved residue and the remaining residue of the active ingredient can be further suppressed.

  The mass ratio of zinc oxide to threonines is preferably in the range of 1: 1.5 to 1: 4, more preferably in the range of 1: 1.5 to 1: 3. In other words, the value of the mass ratio of zinc oxide / threonine is preferably in the range of 0.25 to 0.67, and more preferably in the range of 0.33 to 0.67. When the value of the mass ratio of zinc oxide / threonine is 0.25 or more, zinc oxide does not decrease too much, and the reduction of the deodorizing effect by zinc oxide can be suppressed. When the value of the mass ratio of zinc oxide / threonine is 0.67 or less, zinc oxide does not increase excessively, and the solubility of the active ingredient can be further improved. That is, when the mass ratio of zinc oxide and threonines is within the above range, it is possible to suppress a reduction in deodorizing effect due to zinc oxide, and to further suppress undissolved residual active ingredients.

  Specific examples of the aqueous solvent include water and a mixed solvent of water and alcohol. Water includes tap water and purified water. The purified water includes ion exchange water, distilled water, pure water, ultrapure water, and RO membrane water. Alcohol includes ethanol, methanol and isopropyl alcohol.

  The content of the active ingredient (that is, the total content of zinc oxide, glycine and threonine) is preferably 2.5% by mass or more and 8.5% by mass with respect to the total mass of the deodorant (in this case, the stock solution). % Or less, and more preferably 4.0% by mass or more and 7.0% by mass or less. The stock solution of deodorant may be used as it is, but it may be diluted with an aqueous solvent up to 250 times. When the deodorant stock solution is diluted 250 times, the lower limit of the preferable content of the active ingredient is 0.010% by mass, and the lower limit of the more preferable content of the active ingredient is 0.016% by mass. Even if diluted, it still has a deodorizing effect, and the remaining undissolved and traced active ingredients are further suppressed.

  The deodorant preferably further contains an amphoteric surfactant. Specific examples of amphoteric surfactants include lauryl betaine (Levon LD-36: Sanyo Chemical Industries), lauramidopropyl betaine, myristamidopropyl betaine, sodium cocoamphoacetate, sodium lauroamphoacetate, sodium lauramide propionate, cocamide Sodium propionate, stearyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyetherimidazolium betaine, sodium β-alkylaminopropionate, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, 2 -Alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, sodium laurylaminodipropionate, palm kernel fatty acid amidopropyl betaine and lauramide pro Le hydroxy sultaine and the like. When the deodorant further contains such an amphoteric surfactant, the remaining undissolved active ingredient can be further suppressed.

  When the deodorant further contains an amphoteric surfactant, the content of the amphoteric surfactant is preferably more than 0.08% by mass with respect to the total mass of the deodorant (in this case, the stock solution). In the range of less than 22% by mass, and more preferably in the range of 0.1% by mass to 19% by mass. When the content of the amphoteric surfactant exceeds 0.08% by mass, the remaining undissolved active ingredient can be further suppressed, and the transparency of the deodorant can be ensured. When the content of the amphoteric surfactant is less than 22% by mass, the trace of the deodorant can be further suppressed. That is, when the content of the amphoteric surfactant is within the above range, the trace can be further suppressed while ensuring the transparency of the deodorant.

  The deodorant can be prepared by blending zinc oxide, glycine, threonine and an aqueous solvent, further blending an amphoteric surfactant as necessary, and stirring the blend.

  The deodorant can be used by putting it in a spray container and spraying it in the form of a mist. Further, a deodorant and a propellant (liquefied gas or compressed gas) may be put in a spray container and sprayed into an aerosol form for use. The deodorant can be used by spraying it on an object that causes odor. A specific example of the object is a fiber product, but is not particularly limited.

3. Summary As described above, the deodorant according to the first aspect contains zinc oxide, glycine, threonines, and an aqueous solvent. The threonine includes at least one selected from the group consisting of threonine and threonine derivatives.

  According to this aspect, it is possible to suppress undissolved residue and traces of the active ingredient while having good deodorizing properties.

  In the deodorizer according to the second aspect, in the first aspect, the mass ratio of the glycine and the threonine is in the range of 1: 2 to 2: 1.

  According to this aspect, the undissolved residue and the trace residue of an active ingredient can further be suppressed.

  In the deodorizer according to the third aspect, in the first or second aspect, the mass ratio of the zinc oxide to the threonine is in the range of 1: 1.5 to 1: 4.

  According to this aspect, it is possible to suppress the reduction of the deodorizing effect due to zinc oxide, and it is possible to further suppress the remaining undissolved active ingredient.

  The deodorizer which concerns on a 4th aspect further contains an amphoteric surfactant in any one of the 1st-3rd aspect.

  According to this aspect, the remaining undissolved active ingredient can be further suppressed.

  In the fourth aspect, the deodorant according to the fifth aspect has a content of the amphoteric surfactant of more than 0.08% by mass and less than 22% by mass with respect to the total mass of the deodorant. Within range.

  According to this aspect, the trace residue can be further suppressed while ensuring the transparency of the deodorant.

  Hereinafter, the present disclosure will be specifically described by way of examples. However, the present disclosure is not limited to the examples.

1. Experiment 1
(1) Preparation of deodorant Zinc oxide, glycine, threonine (threonine) and aqueous solvent (ion-exchanged water) are mixed in a glass bottle at the ratio shown in Table 1, and this mixture is stirred for 30 minutes. The deodorant (stock solution) of each Example and Comparative Example was prepared.

(2) Test (2.1) Undissolved residue The deodorizer in the glass bottle after stirring for 30 minutes was observed. Based on this observation result, the undissolved residue was evaluated according to the following criteria.

A: There is no sediment and suspended matter B: A sediment is visible at the bottom of the bottle C: A sediment is laminated at the bottom of the bottle Note that the description such as “A-B” is an intermediate evaluation between A and B This also applies to the following.

(2.2) Deodorant The deodorant was diluted 20 times with ion-exchanged water to prepare a deodorant aqueous solution (5% by mass). 5 mL of a deodorant aqueous solution was injected into the flask with a micropipette. Furthermore, hydrogen sulfide gas was injected into the flask at 100 ppm / L with a syringe, the flask was stoppered and allowed to stand for 5 minutes. Thereafter, the hydrogen sulfide concentration in the flask was measured with a gas detector tube. Based on this measurement result, the deodorizing property was evaluated according to the following criteria.

A: Deodorization rate 80% or more B: Deodorization rate 20% or more and less than 80% C: Deodorization rate less than 20%

(2.3) Remaining trace 10 μL of deodorant (stock solution) with a micropipette (manufactured by Nichiyo Co., Ltd., product number: NichipetEX NPX-100) pipette man (Gilson Company) and a glass plate (Matsunami Glass Industrial Co., Ltd., product number: S9213) It was attached to the upper surface of a large slide glass. This glass plate was placed in a thermostat set at 105 ° C. and heated for 60 minutes. Then, the glass plate was taken out from the thermostat and the upper surface was observed. Based on the observation results, the remaining marks were evaluated according to the following criteria.

A: Trace remains transparent B: Trace remains translucent C: Trace remains white

  In Experiment 1, the effect by the difference of the combination of an active ingredient was verified.

  As is clear from Table 1, Examples 1-2 to 1-6 were satisfactory in all points of undissolved, deodorant properties and traces.

  On the other hand, in Comparative Example 1-1 that does not contain threonines, traces occurred. In Comparative Example 1-7 not containing glycine, undissolved residue was generated. Furthermore, Comparative Example 1-8 containing neither glycine nor threonine was bad in all the points of undissolved, deodorizing property and trace.

  As mentioned above, it turned out that combined use of a zinc oxide, glycine, and threonine is effective as an active ingredient.

2. Experiment 2
(1) Preparation of deodorant In the ratio shown in Table 2, zinc oxide, glycine, threonine (threonine), amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) are put in a glass bottle and formulated. The deodorizer of each Example and Comparative Example was prepared by stirring this formulation for 30 minutes. In addition, about the amphoteric surfactant (lauryl betaine), the density | concentration of 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Test (2.1) Undissolved residue, deodorant property and trace residue In the same manner as in Experiment 1, a test for undissolved component, deodorant property and trace residue was performed.

(2.2) Transparency The deodorant in the glass bottle after stirring for 30 minutes was observed. Based on this observation result, transparency was evaluated according to the following criteria.

A: colorless and transparent B: blue-white to translucent C: cloudiness

  In Experiment 2, the effect of using an amphoteric surfactant was verified.

  As is clear from Table 2, from the comparison of Examples and Comparative Examples, even when an amphoteric surfactant is added, as in Experiment 1, the combined use of zinc oxide, glycine and threonine is effective as an active ingredient. It turns out that.

  Moreover, it was found from the comparison between each Example in Experiment 1 and each Example in Experiment 2 that when the amphoteric surfactant was used, the undissolved residue was generally suppressed.

  Furthermore, from the results of Examples 2-2 to 2-3.5, it was found that it is more effective that the mass ratio of glycine to threonine is in the range of 2: 1 to 19:17. That is, in these Examples, it is the best in all the points of undissolved, deodorant, trace and transparency.

3. Experiment 3
(1) Preparation of deodorant Zinc oxide, glycine, threonine (threonine), alanine, sarcosine, phenylalanine, amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) at a ratio shown in Table 3 in a glass bottle The deodorant of each Example and Comparative Example was prepared by mixing in and mixing the mixture for 30 minutes. In addition, about the amphoteric surfactant (lauryl betaine), the density | concentration of 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Test In the same manner as in Experiment 2, tests of undissolved, deodorant, trace and transparency were performed.

  In Experiment 3, the effect when the amino acid in the active ingredient was glycine alone and when it was glycine and other amino acids was verified. Other amino acids are specifically threonines, alanine, sarcosine and phenylalanine.

  As is clear from Table 3, the comparison of each example and comparative example showed that the combination of glycine and threonine was the best.

4). Experiment 4
(1) Preparation of deodorant In the ratio shown in Table 4, zinc oxide, glycine, threonine (threonine), amphoteric surfactant (lauryl betaine) and aqueous solvent (ion-exchanged water) are put in a glass bottle and blended. The deodorant of each Example was prepared by stirring this formulation for 30 minutes. In addition, about the amphoteric surfactant (lauryl betaine), the density | concentration of 36 mass% lauryl betaine aqueous solution was adjusted and used.

(2) Test In the same manner as in Experiment 2, tests of undissolved, deodorant, trace and transparency were performed.

  In Experiment 4, the effect due to the difference in the content of amphoteric surfactant was verified.

  As is clear from Table 4, from each example, it was found that the content of the amphoteric surfactant is preferably in the range of more than 0.08% by mass and less than 22% by mass.

Claims (5)

Containing zinc oxide, glycine, threonine, and aqueous solvent,
The threonine includes at least one selected from the group consisting of threonine and threonine derivatives,
Deodorants. The mass ratio of the glycine to the threonines is in the range of 1: 2 to 2: 1;
The deodorizer according to claim 1. The mass ratio of the zinc oxide to the threonine is in the range of 1: 1.5 to 1: 4;
The deodorant of Claim 1 or 2. Further containing an amphoteric surfactant,
The deodorizer of any one of Claims 1-3. The content of the amphoteric surfactant is within the range of more than 0.08% by mass and less than 22% by mass with respect to the total mass of the deodorant.
The deodorizer according to claim 4.