WO2017047968A1 - Nouveau lactobacillus présentant diverses fonctions et son utilisation - Google Patents

Nouveau lactobacillus présentant diverses fonctions et son utilisation Download PDF

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Publication number
WO2017047968A1
WO2017047968A1 PCT/KR2016/009994 KR2016009994W WO2017047968A1 WO 2017047968 A1 WO2017047968 A1 WO 2017047968A1 KR 2016009994 W KR2016009994 W KR 2016009994W WO 2017047968 A1 WO2017047968 A1 WO 2017047968A1
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WIPO (PCT)
Prior art keywords
lactobacillus
bifidobacterium
lactic acid
rdna
acid bacteria
Prior art date
Application number
PCT/KR2016/009994
Other languages
English (en)
Korean (ko)
Inventor
김동현
한명주
Original Assignee
경희대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020160005018A external-priority patent/KR20170032816A/ko
Priority to MX2018003230A priority Critical patent/MX2018003230A/es
Priority to CA2998841A priority patent/CA2998841C/fr
Priority to US15/759,915 priority patent/US11202811B2/en
Priority to AU2016322617A priority patent/AU2016322617B2/en
Priority to JP2018513778A priority patent/JP6608047B2/ja
Priority to CN201680066778.XA priority patent/CN108473944B/zh
Priority to RU2018113245A priority patent/RU2734031C2/ru
Application filed by 경희대학교 산학협력단 filed Critical 경희대학교 산학협력단
Priority to CN202210200178.5A priority patent/CN114410548B/zh
Priority to BR112018005195-0A priority patent/BR112018005195A2/pt
Priority to SG11201802144TA priority patent/SG11201802144TA/en
Priority to EP16846789.2A priority patent/EP3351617A4/fr
Publication of WO2017047968A1 publication Critical patent/WO2017047968A1/fr
Priority to PH12018500566A priority patent/PH12018500566A1/en
Priority to AU2020202144A priority patent/AU2020202144B2/en
Priority to US17/455,328 priority patent/US11771725B2/en

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C12R2001/24—Lactobacillus brevis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne une nouvelle souche de Lactobacillus sp., une nouvelle souche de Bifidobacterium sp. ou un mélange de lactobacillus correspondants, qui est isolé(e) à partir de kimchi ou de matières fécales humaines. Selon la présente invention, la souche spécifique de Lactobacillus sp. ou la souche spécifique de Bifidobacterium sp. est isolée à partir de kimchi ou de matières fécales humaines, présentant ainsi une sécurité élevée et diverses activités physiologiques telles qu'une activité antioxydante, une activité inhibitrice de ß-glucuronidase, un activité inhibitrice de génération de lipopolysaccharides (LPS) ou une activité d'induction d'expression de protéines de jonction serrée. Par conséquent, selon la présente invention, la souche spécifique de Lactobacillus sp., la souche spécifique de Bifidobacterium sp. ou un mélange de lactobacillus correspondants peut être utilisé(e) comme aliment fonctionnel et matériau de médicament utiles pour empêcher, atténuer ou traiter une lésion de l'intestin, une lésion hépatique, des allergies, des maladies inflammatoires ou l'obésité.
PCT/KR2016/009994 2015-09-15 2016-09-07 Nouveau lactobacillus présentant diverses fonctions et son utilisation WO2017047968A1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
EP16846789.2A EP3351617A4 (fr) 2015-09-15 2016-09-07 Nouveau lactobacillus présentant diverses fonctions et son utilisation
RU2018113245A RU2734031C2 (ru) 2015-09-15 2016-09-07 Новая лактобактерия, характеризующаяся различными функциями, и ее применение
US15/759,915 US11202811B2 (en) 2015-09-15 2016-09-07 Lactobacillus having various functions, and use thereof
AU2016322617A AU2016322617B2 (en) 2015-09-15 2016-09-07 Novel lactobacillus having various functions, and use thereof
CN202210200178.5A CN114410548B (zh) 2015-09-15 2016-09-07 具有各种功能的新型乳酸杆菌及其用途
CN201680066778.XA CN108473944B (zh) 2015-09-15 2016-09-07 具有各种功能的新型乳酸杆菌及其用途
CA2998841A CA2998841C (fr) 2015-09-15 2016-09-07 Nouveau lactobacille ayant diverses fonctions, et utilisation connexe pour la prevention ou le traitement des blessures au foie, des blessures intestinales, des allergies, de l'inflammation ou de l'obesite
MX2018003230A MX2018003230A (es) 2015-09-15 2016-09-07 Nuevo lactobacilo con diversas funciones y su uso.
JP2018513778A JP6608047B2 (ja) 2015-09-15 2016-09-07 多様な機能性を有する新規乳酸菌およびその用途
BR112018005195-0A BR112018005195A2 (pt) 2015-09-15 2016-09-07 lactobacillus plantarum lc27, composição farmacêutica para a prevenção ou tratamento de uma ou mais doenças, composição alimentícia para a prevenção ou tratamento de uma ou mais doenças, método de prevenção ou tratamento de uma ou mais doenças, e uso de uma composição que compreende lactobacillus plantarum lc27
SG11201802144TA SG11201802144TA (en) 2015-09-15 2016-09-07 Novel lactobacillus having various functions, and use thereof
PH12018500566A PH12018500566A1 (en) 2015-09-15 2018-03-15 Novel lactobacillus having various functions, and use thereof
AU2020202144A AU2020202144B2 (en) 2015-09-15 2020-03-26 Novel lactobacillus having various functions, and use thereof
US17/455,328 US11771725B2 (en) 2015-09-15 2021-11-17 Lactobacillus having various functions, and use thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20150130124 2015-09-15
KR10-2015-0130124 2015-09-15
KR1020160005018A KR20170032816A (ko) 2015-09-15 2016-01-15 다양한 기능성을 가진 신규 유산균 및 이의 용도
KR10-2016-0005018 2016-01-15

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US15/759,915 A-371-Of-International US11202811B2 (en) 2015-09-15 2016-09-07 Lactobacillus having various functions, and use thereof
US17/455,328 Continuation US11771725B2 (en) 2015-09-15 2021-11-17 Lactobacillus having various functions, and use thereof

Publications (1)

Publication Number Publication Date
WO2017047968A1 true WO2017047968A1 (fr) 2017-03-23

Family

ID=58289199

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/009994 WO2017047968A1 (fr) 2015-09-15 2016-09-07 Nouveau lactobacillus présentant diverses fonctions et son utilisation

Country Status (1)

Country Link
WO (1) WO2017047968A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019103198A1 (fr) * 2017-11-24 2019-05-31 주식회사 고바이오랩 Souche de lactobacillus fermentum kbl 375 et son utilisation
KR102058622B1 (ko) 2019-08-27 2019-12-23 주식회사 아미코스메틱 여드름 유발 피부상재균에 대한 항균 활성을 갖는 락토바실러스 쿠르바투스
US10668116B2 (en) 2014-10-31 2020-06-02 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
CN112111430A (zh) * 2020-09-27 2020-12-22 吉林农业大学 一种抗氧化与抗衰老双效益生菌及其应用
CN113604400A (zh) * 2021-08-26 2021-11-05 王玉莹 具有预防或治疗糖尿病作用的新型乳杆菌yuyingw
US11202811B2 (en) 2015-09-15 2021-12-21 University-Industry Cooperation Group Of Kyung Hee University Lactobacillus having various functions, and use thereof
US11583558B2 (en) 2017-08-30 2023-02-21 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080075971A (ko) * 2007-02-14 2008-08-20 (주)네오팜 프로바이오틱스 복합 제제
KR101470347B1 (ko) * 2012-12-31 2014-12-10 재단법인 전남생물산업진흥원 황금엑스 발효물을 함유한 간손상 보호용 조성물

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080075971A (ko) * 2007-02-14 2008-08-20 (주)네오팜 프로바이오틱스 복합 제제
KR101470347B1 (ko) * 2012-12-31 2014-12-10 재단법인 전남생물산업진흥원 황금엑스 발효물을 함유한 간손상 보호용 조성물

Non-Patent Citations (4)

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Title
KARCZEWSKI, JURGEN ET AL.: "Regulation of Human Epithelial Tight Junction Proteins by Lactobacillus plantarum In Vivo and Protective Effects on the Epithelial Barrier", AMERICAN JOURNAL OF PHYSIOLOGY GASTROINTESTINAL AND LIVER PHISIOLOGY, vol. 298, no. 6, 11 March 2010 (2010-03-11), pages G851 - G859, XP055373219 *
See also references of EP3351617A4 *
SULTANA, RESHMA ET AL.: "Strain-dependent Augmentation of Tight-junction Barrier Function in Human Primary Epidermal Keratinocytes by Lactobacillus and Bifi-dobacterium Lysates", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 79, no. 16, 14 June 2013 (2013-06-14), pages 4887 - 4894, XP055373211 *
ULLUWISHEWA, DULANTHA ET AL.: "Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components", THE JOURNAL OF NUTRITION, vol. 141, no. 5, 23 March 2011 (2011-03-23), pages 769 - 776, XP055373216 *

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11213556B2 (en) 2014-10-31 2022-01-04 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US11931387B2 (en) 2014-10-31 2024-03-19 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US10668116B2 (en) 2014-10-31 2020-06-02 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US10675312B2 (en) 2014-10-31 2020-06-09 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US10842830B2 (en) 2014-10-31 2020-11-24 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US10842831B2 (en) 2014-10-31 2020-11-24 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US11364270B2 (en) 2014-10-31 2022-06-21 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US11278580B2 (en) 2014-10-31 2022-03-22 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
US11202811B2 (en) 2015-09-15 2021-12-21 University-Industry Cooperation Group Of Kyung Hee University Lactobacillus having various functions, and use thereof
US11771725B2 (en) 2015-09-15 2023-10-03 University-Industry Cooperation Group Of Kyung Hee University Lactobacillus having various functions, and use thereof
US11583558B2 (en) 2017-08-30 2023-02-21 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders
WO2019103198A1 (fr) * 2017-11-24 2019-05-31 주식회사 고바이오랩 Souche de lactobacillus fermentum kbl 375 et son utilisation
KR102058622B1 (ko) 2019-08-27 2019-12-23 주식회사 아미코스메틱 여드름 유발 피부상재균에 대한 항균 활성을 갖는 락토바실러스 쿠르바투스
CN112111430A (zh) * 2020-09-27 2020-12-22 吉林农业大学 一种抗氧化与抗衰老双效益生菌及其应用
CN112111430B (zh) * 2020-09-27 2022-10-21 吉林农业大学 一种抗氧化与抗衰老双效益生菌及其应用
CN113604400A (zh) * 2021-08-26 2021-11-05 王玉莹 具有预防或治疗糖尿病作用的新型乳杆菌yuyingw
CN113604400B (zh) * 2021-08-26 2023-06-02 王玉莹 具有预防或治疗糖尿病作用的新型乳杆菌yuyingw

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