WO2016167104A1 - 近視進行抑制用コンタクトレンズならびにその設計方法および製造方法 - Google Patents
近視進行抑制用コンタクトレンズならびにその設計方法および製造方法 Download PDFInfo
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- WO2016167104A1 WO2016167104A1 PCT/JP2016/059802 JP2016059802W WO2016167104A1 WO 2016167104 A1 WO2016167104 A1 WO 2016167104A1 JP 2016059802 W JP2016059802 W JP 2016059802W WO 2016167104 A1 WO2016167104 A1 WO 2016167104A1
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- contact lens
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- myopia progression
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/041—Contact lenses for the eyes bifocal; multifocal
- G02C7/044—Annular configuration, e.g. pupil tuned
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C2202/00—Generic optical aspects applicable to one or more of the subgroups of G02C7/00
- G02C2202/04—Lenses comprising decentered structures
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C2202/00—Generic optical aspects applicable to one or more of the subgroups of G02C7/00
- G02C2202/24—Myopia progression prevention
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/024—Methods of designing ophthalmic lenses
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- the present invention relates to a contact lens having a myopia progression inhibitory effect used to suppress the progression of myopia in the human eye, and in particular, the myopia progression inhibitory effect that the present inventor has newly found.
- the present invention relates to a novel method for designing a contact lens for suppressing myopia progression based on the obtained optical and physiological mechanisms.
- myopia in the human eye not only causes inconvenience in daily life, but also increases the risk of possessing lesions such as retinal detachment and glaucoma as myopia increases. Particularly in recent years, the prevalence of myopia has increased, so the social demand for myopia progression suppression technology has also increased.
- the former contact lens for suppressing myopia progression based on the theory of off-axis aberrations causes a hyperopic focus error in incident light tilted with respect to the optical axis direction in myopic eyes with a long ocular length. This is based on the idea that it causes the progression of myopia. Therefore, by setting a predetermined addition power (Add) to the incident light inclined with respect to the optical axis direction, and returning the focal position having the far-sighted focal error outside the optical axis shifted from the retina to the front of the retina. It is intended to suppress myopia progression due to further growth of the axial length.
- Add addition power
- a contact lens for suppressing myopia progression based on the latter adjustment lag theory is an incomplete adjustment amount (adjustment stimulus and adjustment stimulus) generated to minimize the adjustment amount to the extent that the human eye is not aware of image blur when focusing.
- the adjustment lag which is the difference in adjustment response, causes myopia progression due to hyperextension of the axial length as a hyperopic focus error.
- the focal position having the hyperopic focus error on the optical axis is reduced or eliminated and brought closer to the retina, so that the length of the axial axis is increased. It tries to suppress myopia progression due to further growth.
- the former myopia progression suppression contact lens based on the off-axis aberration theory takes about + 2.0D (diopter) to correct the hyperopic focus error in the peripheral part of the retina when the lens displacement on the cornea is taken into account.
- a high addition power is required.
- QOV quality of appearance
- the light condensing rate on the retina is lowered and a myopic focus error is likely to occur during far vision.
- Sankaridurg et al. P. Sankaridurg et al. Decrese inRate of Myopia Progression with a Contact Lens Designed to Reduce Relative Peripheral Hyperopia: One-Year Results.
- the present inventors have conducted research on the provision of contact lenses for suppressing myopia progression based on the latter adjustment lag theory, and as a result, there is an unexpected conclusion that the myopia progression suppression action itself based on the adjustment lag theory was erroneous. I came to get. Although the specific facts will be described later with experimental results, conventionally, the adjustment lag on the optical axis of the eye that occurs during near vision can be suppressed by setting an additional power on the contact lens, thereby enabling hyperopia. Although it was thought that it was possible to suppress the overextension of the axial length due to sexual focus error, the adjustment lag on the optical axis of the eye that occurs during near vision can be adjusted even if the additional power is set on the contact lens. I learned the new fact that it cannot be suppressed significantly.
- the present inventor has found a new optical and physiological mechanism for obtaining a myopia progression inhibitory effect, and has also confirmed it through experiments. Based on this, the present invention relating to a novel method for designing a contact lens for suppressing myopia progression, which has not been heretofore, has been completed.
- the present invention has been made in the background of the above-mentioned circumstances, and the problem to be solved is a contact lens having a myopia progression suppression ability based on the mechanism of the myopia progression suppression effect newly found by the present inventor.
- the object is to provide a design method and a manufacturing method, and a novel contact lens for suppressing myopia progression.
- the present invention relating to a novel design method for a contact lens for suppressing the progression of myopia is characterized by the improvement of aberrations off the optical axis and the adjustment on the optical axis with respect to the correction power necessary for realizing proper correction.
- a method of designing a contact lens for suppressing myopia progression that provides a correction region.
- the present invention relating to a novel method for manufacturing a contact lens for suppressing myopia progression is characterized in that the correction power of the appropriate correction region set in accordance with the method for designing a contact lens for suppressing myopia according to the present invention described above. And a lens front-rear surface shape that realizes the additional power of the accommodation tension relief region, and a contact lens having such a lens front-rear surface shape is manufactured.
- the feature of the present invention relating to a novel contact lens for suppressing myopia progression is that it is necessary to realize proper correction without improving aberrations off the optical axis and adjusting lag on the optical axis.
- An adjustment tension alleviation area set with a maximum value of +0.25 to +0.75 diopters is provided as an additional power that can relieve the adjustment tension with respect to a correct correction power, and such an additional power is set at least on the optical center.
- There is a contact lens for suppressing myopia progression provided with an appropriate correction area.
- the appropriate correction region set in the central portion for example, the appropriate correction region set in the central portion, the constant addition power region provided with a predetermined radial width in the outer peripheral portion of the optical portion, A mode in which a gradual addition power region that gradually changes from the appropriate correction region toward the constant addition power region is provided, and the adjustment tension relaxation region is configured by the constant addition power region and the gradual addition power region.
- the appropriate correction region set in the central portion the constant addition power region provided with a predetermined radial width in the outer peripheral portion of the optical portion
- the gradually added power region is set to 0 mm ⁇ r where r is a radial dimension from the optical center.
- a mode in which the addition power is set within the range of ⁇ 3.5 mm and the addition power at the outermost peripheral portion of the gradually changing power addition area is set to +0.25 to +0.75 diopter is preferably employed.
- the present invention presents a new optical and physiological mechanism for the suppression of myopia progression instead of the myopia progression suppression action based on the conventional adjustment lag theory that was proposed as a desktop theory, and was devised by the present inventor. This is based on what can be confirmed by the experimental method. And, according to the design method according to the present invention, an effective myopia progression suppression contact lens capable of presenting myopia progression suppression ability theoretically and experimentally even in a situation where the myopia progression suppression action based on the adjustment lag theory is denied. Can be designed while ensuring a good quality of appearance (QOV) during wearing.
- QOV quality of appearance
- the manufacturing method according to the present invention it is possible to manufacture a contact lens having both an effective myopia suppression ability and a good QOV when worn with the optical characteristics obtained by the design method of the present invention. become.
- the contact lens having the structure according to the present invention has an optical and physiological mechanism that can be explained theoretically and experimentally in a situation where the myopia progression suppressing action based on the adjustment lag theory is denied. Based on this, an effective myopia suppression effect and a good QOV at the time of wearing can be exhibited.
- BRIEF DESCRIPTION OF THE DRAWINGS Explanatory drawing for demonstrating the measuring apparatus and method of an eye accommodation reaction amount using the front open type binocular wavefront sensor which this inventor devised.
- the graph which shows the measurement result of QOV using the evaluation scale of FIG. Explanatory drawing for demonstrating the theory based on the optical and physiological mechanism of the myopia progress inhibitory effect discovered by this inventor.
- the front view which illustrates the contact lens of the structure according to the present invention.
- the incident optical path in the myopic eye 10 is shown.
- the myopic eye 10 has a naked eye focal point A positioned in front of the cornea 16 with respect to the retina 14 on the optical axis with respect to a substantially parallel incident light assuming far vision. So that a clear image cannot be recognized in a distance view. Therefore, by wearing the contact lens 12 on the cornea 16 having an appropriate correction power that gives an appropriate visual acuity for distance vision, the focus of the substantially parallel incident light beam is changed to the retina 14 as shown by the solid line in FIG. It is the position of the proper correction focus B, which is the upper approximate fovea.
- the adjustment of the near vision focus C by the adjustment ability of the myopic eye 10 is generally adjusted by an amount that does not reach the appropriate position on the retina 14, and as shown by a two-dot chain line in FIG.
- the position of the near vision focal point C ′ that gives clear vision without inconvenience without reaching the retina 14 is set.
- the difference on the optical axis between the near vision focus C ′ and the proper focus position on the retina 14 is referred to as “adjustment lag”.
- the size of this adjustment lag is recognized as an under-adjustment of 0.50 to 0.75 diopters on average for young people aged 20 to 25 years with respect to the adjustment stimulus set with an index of 40 cm in front of the eyes.
- the lack of adjustment of the human eye during near vision is considered to be a cause of myopia progression due to the growth of the axial length.
- myopia progression suppression based on the conventional adjustment lag theory can adjust the adjustment lag according to the additional power set to the contact lens 12 to be worn, and the adjustment lag changes according to the magnitude of the additional power. It is assumed that.
- the contact lens 12 that gives a far vision focal point that is appropriately corrected on the optical axis, and is worn on the same subject by using four types of test lenses with different addition powers set in the periphery.
- the change in the adjustment lag was actually measured, no correlation was found between the added power and the adjustment lag, as shown in FIG. Specifically, the contact lens 12 in which the addition powers of + 0.25D, + 0.50D, + 0.75D, and + 1.00D are set in a mode of gradually increasing from the appropriate correction power set at the center of the optical unit toward the periphery.
- the adjustment lag generated in near vision at 40 cm in front of the eye corresponding to the adjustment stimulus amount of ⁇ 2.5D was measured. As shown in FIG.
- the adjustment lag tends to decrease when a lens with an added power of + 0.25D is used, compared to a spherical contact lens (control) that gives an appropriate correction focus. It is clear that the adjustment lag cannot be improved by the added power because the adjustment lag may be increased even if the power is increased.
- the mechanism of myopia progression suppression mechanism based on the adjustment lag theory is to suppress the progression of myopia by wearing a contact lens with a set addition power and appropriately improving the adjustment lag depending on the addition power. I must admit that there was an error.
- the present inventor made progress of myopia by wearing a contact lens with an additional power set in the peripheral part, as compared with the case of wearing a spherical contact lens that gives an appropriate correction focus by past statistics and experiments. It has been confirmed that the effect itself of suppressing the above is recognized. Therefore, there is an error in the logic of the mechanism of myopia progression suppression based on the adjustment lag theory, and it is considered that there is another correct logic as a mechanism of myopia progression suppression with a contact lens with a set addition power. Went. In particular, the present inventor succeeded in objectively measuring the amount of lens accommodation under contact lens wearing, which could not be achieved conventionally, by devising a new experimental device and experimental method.
- FIG. 3 shows the basic structure of the experimental apparatus used by the present inventors.
- This experimental apparatus uses a binocular wavefront sensor of an open front type, and the subject is positioned in front of each of the right eye 20 and the left eye 22 in which the head is positioned with the chin rest and forehead fixed.
- a wavefront sensor 24 for the right eye and a wavefront sensor 26 for the left eye via half mirrors 28 and 30, respectively.
- Wavefront sensors are well known in the field of eye optics. For example, the wavefront aberration in reflected light from the macular of the eyeball projected with measurement light is measured using a Shack-Hartmann sensor, and the measurement results are used.
- the optical characteristics of the eye can also be obtained based on the distortion of the wave front having the same phase.
- the indicators 32 and 34 can be visually recognized by wearing the contact lens 12 only in one eye (for example, the right eye) 20.
- an index 32 for near vision with a viewing distance of 40 cm and an index 34 for far vision with a viewing distance of 5 m were used.
- the other eye (for example, the left eye) 22 was a naked eye without wearing a contact lens, and a shielding plate 36 was installed instead of the index.
- the naked eye (the left eye shown in the figure) 22 can measure the amount of adjustment of the lens of the eye, which is an adjustment reaction of the naked eye synchronized with the lens wearing eye (the right eye shown in the figure) 20.
- the contact lens 12 was worn on each dominant eye of the subject, and the difference in the amount of adjustment of the lens of the eye between when the index 32 with a visual distance of 40 cm was observed and when the index 34 with a visual distance of 5 m was observed.
- the measured value of the adjustment amount obtained in this way is measured for the naked eye, and the change in the amount of adjustment of the eye when changing from far vision to near vision (change in eye refractive power) is contacted. It can be obtained as an adjustment amount in the crystalline lens of the eye excluding the optical characteristics of the lens.
- the measurement used four types of contact lenses 12 in which the peripheral addition power (Add) was set to + 0.25D, + 0.50D, + 0.75D, and + 1.00D, respectively. .
- the peripheral addition power (Add) was set to + 0.25D, + 0.50D, + 0.75D, and + 1.00D, respectively.
- the effect of the change of the addition power on the change of the adjustment amount of the naked eye (non-wearing eye) was measured. .
- the lens power distribution in each contact lens 12 used is shown in FIG. Further, the lens power on the optical center of the contact lens 12 of each additional power is the same as the lens power of control, and is completely corrected with glasses as necessary so as to be an appropriate correction power.
- the contact lenses 12 having four types of addition powers were randomly worn by the subject, and the correction values with the glasses were constant.
- FIG. 5 shows the actual measurement results obtained by measuring five subjects with measured average values.
- the average age of 5 subjects was 36.4 ⁇ 6.3 years.
- the average refraction value of the eyes of the five subjects is that the spherical lens power (P) is ⁇ 1.61 ⁇ 2.01D, the cylindrical lens power (C) is ⁇ 0.27 ⁇ 1.10D, and the cylinder axis angle.
- P spherical lens power
- C cylindrical lens power
- A was 87.3 ⁇ 6.0 degrees.
- the quality of appearance was also measured together with the measurement of the amount of eye adjustment while wearing each contact lens 12.
- QOV quality of appearance
- it is widely used as an index when acquiring subjective pain and distress as objective data in the medical field for how to see with contact lens wearing eyes in both far vision and near vision It was measured by obtaining a subjective evaluation of the subject using a visual evaluation scale (VAS: Visual Analog Scale).
- VAS Visual Analog Scale
- FIG. 6 the VAS actually used is checked at the corresponding position on the linear evaluation line drawn in the center, and each subject checked. The position is scored by an analog distance where the left end of the line is 0 and the right end of the line is 100, and the measurement result is obtained.
- FIG. 7 The visual measurement results obtained in this way are shown in FIG. 7 with the average value of the VAS evaluation points. From the measurement result of FIG. 7, it can be seen that there is almost no effect on near vision with respect to the change in the addition power of the contact lens 12 to be worn. On the other hand, in distant vision, it drops from around + 0.50D, and although it received an evaluation of 69 points at + 0.75D, it was evaluated at 37 points at + 1.00D. It can be seen that the evaluation is below the 50 points, which is considered to be a possible lower limit.
- the size of the adjustment lug generated during near vision is improved by setting the added power, that is, the magnitude of the added power.
- the added power that is, the magnitude of the added power.
- the amount of adjustment of the lens to which the eye reacts during near vision can be relaxed by setting the addition power. It can be confirmed that it is possible to reduce the amount of adjustment of the lens according to the magnitude of the frequency. That is, it is possible to reduce the amount of adjustment caused to the crystalline lens during near vision by wearing the contact lens 12 with the added power set, compared to wearing the spherical contact lens 12. It is also possible to control the adjustment amount of the lens by the addition power.
- the myopic eye 10 as a human eye having a naked eye focus (A) ahead of the retina 14 on the optical axis in the distance vision as shown in FIG.
- a contact lens with a set power is worn.
- myopia is overcorrected in near vision, and the back is focused behind the retina 14. Therefore, in the near vision, the near vision focus is adjusted to the retina 14 side by the adjustment ability of the crystalline lens 38 of the myopic eye 10 to make the vision clear.
- the ciliary muscle 40 composed of ring-shaped fibers and meridian fibers is strained to ciliate.
- a compressive external force F in the radial direction is applied from the corpuscle to the crystalline lens 38.
- the tension of the ciliary muscle 40 is also exerted on the inner surface of the eyeball through a saw-toothed edge, etc., and as a result, the force vector of the inner eye muscle including the ciliary muscle 40 becomes stronger. Growth in the equator direction is suppressed, and growth in the axial direction, which is the front-rear direction, is promoted.
- the amount of adjustment in near vision in the appropriately corrected myopic eye that is, the degree of tension of the ciliary muscle 40 is reduced.
- the amount of reduction in the degree of tension of the ciliary muscle 40 in the appropriately corrected myopic eye can be adjusted and set according to the added power.
- the added power is less than + 0.25D, it is difficult to sufficiently relax the adjustment tension and suppress myopia progression based on it.
- the added power exceeds + 0.75D, it will be visible in distance vision. There should also be concern about the risk that it will be difficult to obtain the quality of the person.
- a setting range of the additional power for example, when a contact lens set with an addition power of + 0.5D is worn on a child myopia patient, a wide visual range (ear viewing angle and nose side) with respect to the optical axis of the eye.
- the optical unit 42 provided in the substantially central portion of the contact lens 12 is provided with an appropriate corrected visual acuity in far vision with the myopic eye 10 to be worn on the lens optical axis 18.
- An appropriate correction area in which the appropriate correction power is set is provided, and a gradual addition power area in which an addition power that gradually increases from the lens optical axis 18 toward the outer periphery is provided as an adjustment tension relaxation area.
- the setting of the additional power in the accommodation tension alleviation region is preferably made with a power distribution in the radial direction as shown in FIG.
- the gradual addition power region is set within the range of 0 mm ⁇ r ⁇ 3.5 mm, where r is the radial dimension from the optical center, and the addition is the largest in the outermost peripheral portion of the gradual addition power region. It is preferable that the frequency is +0.25 to +0.75 diopter.
- FIG. 4 it is possible to provide a constant added power region that spreads in the radial direction with a fixed maximum added power at the outermost peripheral portion of the optical unit 42 in accordance with the present invention.
- a constant added power region that spreads in the radial direction with a fixed maximum added power at the outermost peripheral portion of the optical unit 42 in accordance with the present invention.
- it is more suitable for relieving excessive tension of the body muscle 40 and suppressing myopia progression it is not essential to provide such a constant added power region. That is, in FIG. 4, the mode in which the accommodation tension relaxation region is configured by the constant addition power region and the gradual addition power region is illustrated, but the accommodation tension relaxation region is configured only by the gradual addition power region. Also good.
- an additional power distribution that changes stepwise can be adopted, and the change mode of the additional power is limited. It is not something.
- the effect of suppressing myopia progression can be exhibited without affecting the daily life by adopting the setting range and setting pattern of the additional power as described above.
- a soft contact lens for suppressing myopia progression with a power distribution of + 0.5D set according to the present invention with the power distribution shown in FIG. 4 and a power addition as a comparative example are not set.
- the myopia progression-suppressing soft contact lens of the present invention has a corrected visual acuity and a subjective appearance compared to the spherical soft contact lens of the comparative example.
- experimental data has been obtained that the amount of axial length elongation after 12 months is significantly suppressed.
- the correction power and additional power required for realizing proper correction are specifically based on the measurement results of the target human eye adjustment function, for example, the measurement result of the naked eye vision based on the adjustment ability remaining in the lens. Therefore, it is preferable that the setting is made in consideration of the living environment and preferences of the wearer.
- the correction power necessary for realizing proper correction in the central portion of the optical unit that is, the region where the proper correction power is set to give a focal point that forms an image on the retina in the distance vision is not limited to the optical axis. It is also possible to set with a region extending from the axis in the radial direction by a predetermined distance.
- the optical center point at which the optical center axis intersects in the optical unit is matched with the optical axis on the eye optics when the contact lens is worn. Therefore, in the stable position of the contact lens on the cornea, if the contact lens geometric center is out of the center of the pupil, which is the center point on the eye optics, the optical axis of the optical unit is set to the geometric center of the contact lens. A bias may be set. In that case, as means for positioning the contact lens in the circumferential direction on the cornea when the lens is worn, for example, the “Truncation Method” disclosed in Japanese Utility Model Laid-Open No. 48-13048 or the Japanese Patent Laid-Open No.
- a conventionally known cutting method such as a lace cutting method or molding It can be formed in the same manner as in the past by mold forming such as the method, spin casting method, or a combination thereof.
- the addition power setting optical surface is not specified as any one of the front and rear surfaces of the lens, and the addition power setting optical device is considered in consideration of required optical characteristics, dimensions of each part, manufacturing method employed, and the like.
- the surface can be selected and set to the front and back surfaces of the lens. For example, by setting the addition power on the front surface of the lens, it is possible to make the rear surface of the lens a base curve having a curved surface shape corresponding to the corneal shape, and by setting the addition power on the rear surface of the lens, It is also possible to make the manufacturing easier by reducing the types of molds for use.
- the addition power it is possible to set the addition power to be shared between the front surface of the lens and the rear surface of the lens, so that even when the addition power is high, it is possible to suppress a change in shape on the front surface of the lens and the rear surface of the lens.
- a peripheral portion having a shape corresponding to the surface of the eyeball is provided on the outer periphery of the optical portion of the contact lens so as to stabilize the position of the contact lens on the eyeball, like a general myopic contact lens.
- the contact lens to which the present invention is applied may be either a soft type or a hard type.
- the material is not limited.
- a contact lens having a soft type myopia progression suppressing ability in addition to a water-containing material such as a known PHEMA (polyhydroxyethyl methacrylate) or PVP (polyvinylpyrrolidone), an acrylic rubber, Non-hydrous materials such as silicone can also be used.
- a material such as a gas permeable lens (RGP lens) such as PMMA (polymethylmethacrylate) or SiMA / MMA polymer to make a hard type contact lens having the ability to suppress myopia progression.
- the soft type is preferable from the viewpoint of positional stability on the cornea.
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Abstract
Description
Claims (5)
- 適正な矯正の実現に必要な矯正度数に対して、光軸外での収差の改善および光軸上での調節ラグの改善をすることなく調節緊張を緩和し得る付加度数として+0.25~+0.75ディオプターの最大値をもって設定した調節緊張緩和領域を設けると共に、少なくとも光学中心上においてかかる付加度数を設定しない適正矯正領域を設けることを特徴とする近視進行抑制用コンタクトレンズの設計方法。
- 請求項1に記載の設計方法に従って設定された前記適正矯正領域の前記矯正度数と前記調節緊張緩和領域の前記付加度数とを実現するレンズ前後面形状を決定し、かかるレンズ前後面形状を備えたコンタクトレンズを製造することを特徴とする近視進行抑制用コンタクトレンズの製造方法。
- 光軸外での収差の改善および光軸上での調節ラグの改善をすることなく、適正な矯正の実現に必要な矯正度数に対して調節緊張を緩和し得る付加度数として+0.25~+0.75ディオプターの最大値をもって設定した調節緊張緩和領域が設けられていると共に、少なくとも光学中心上においてかかる付加度数を設定しない適正矯正領域が設けられていることを特徴とする近視進行抑制用コンタクトレンズ。
- 中央部分に設定された前記適正矯正領域と、
光学部の外周部分に所定径方向幅で設けた一定付加度数領域と、
該適正矯正領域から該一定付加度数領域に向かって次第に変化する漸変付加度数領域とを設けて、
該一定付加度数領域と該漸変付加度数領域とにより前記調節緊張緩和領域を構成した請求項3に記載の近視進行抑制用コンタクトレンズ。 - 前記漸変付加度数領域が、前記光学中心からの径方向寸法をrとして0mm<r≦3.5mmの範囲内に設定されていると共に、
該漸変付加度数領域の最外周部分における付加度数が+0.25~+0.75ディオプターとされている請求項4に記載の近視進行抑制用コンタクトレンズ。
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
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CN201680021482.6A CN107533241A (zh) | 2015-04-13 | 2016-03-28 | 用于近视发展抑制的接触透镜及其设计方法和制造方法 |
KR1020177027470A KR102522801B1 (ko) | 2015-04-13 | 2016-03-28 | 근시 진행 억제용 콘택트 렌즈 및 그 설계 방법 및 제조 방법 |
EP16779895.8A EP3285109A4 (en) | 2015-04-13 | 2016-03-28 | Contact lens for suppressing progression of myopia, method for designing same, and method for manufacturing same |
SG11201708386TA SG11201708386TA (en) | 2015-04-13 | 2016-03-28 | Contact lens for myopia progression suppression, and designing method and manufacturing method thereof |
US15/251,884 US20160370602A1 (en) | 2015-04-13 | 2016-08-30 | Contact lens for myopia progression suppression, and designing method and manufacturing method thereof |
HK18108140.2A HK1248828A1 (zh) | 2015-04-13 | 2018-06-25 | 用於近視發展抑制的接觸透鏡及其設計方法和製造方法 |
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JP2015082068A JP5923640B1 (ja) | 2015-04-13 | 2015-04-13 | 近視進行抑制用コンタクトレンズの設計方法および製造方法 |
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US15/251,884 Continuation US20160370602A1 (en) | 2015-04-13 | 2016-08-30 | Contact lens for myopia progression suppression, and designing method and manufacturing method thereof |
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US (1) | US20160370602A1 (ja) |
EP (1) | EP3285109A4 (ja) |
JP (1) | JP5923640B1 (ja) |
KR (1) | KR102522801B1 (ja) |
CN (1) | CN107533241A (ja) |
HK (1) | HK1248828A1 (ja) |
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EP3530174A1 (en) * | 2018-02-23 | 2019-08-28 | Essilor International (Compagnie Generale D'optique) | Method for altering the visual performance of a subject, method for measuring the spherical refraction correction need of a subject and optical system for implementing these methods |
CN114391121B (zh) * | 2019-09-12 | 2024-03-26 | 香港理工大学 | 用于延缓近视进展的镜片和方法 |
WO2023279282A1 (en) * | 2021-07-07 | 2023-01-12 | Shenyang Kangende Medical Science And Technology Co., Ltd | Systems, apparatus, and methods for regulating refractive error development through the modulation of peripheral distortion |
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JP2014032404A (ja) * | 2012-07-31 | 2014-02-20 | Johnson & Johnson Vision Care Inc | 近視制御光学素子及びムスカリン様作用薬を組み込むレンズ |
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2016
- 2016-03-28 EP EP16779895.8A patent/EP3285109A4/en not_active Withdrawn
- 2016-03-28 SG SG11201708386TA patent/SG11201708386TA/en unknown
- 2016-03-28 KR KR1020177027470A patent/KR102522801B1/ko active IP Right Grant
- 2016-03-28 WO PCT/JP2016/059802 patent/WO2016167104A1/ja active Application Filing
- 2016-03-28 CN CN201680021482.6A patent/CN107533241A/zh active Pending
- 2016-08-30 US US15/251,884 patent/US20160370602A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
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US20160370602A1 (en) | 2016-12-22 |
SG11201708386TA (en) | 2017-11-29 |
JP5923640B1 (ja) | 2016-05-24 |
CN107533241A (zh) | 2018-01-02 |
JP2016200762A (ja) | 2016-12-01 |
KR20170136520A (ko) | 2017-12-11 |
EP3285109A4 (en) | 2018-10-31 |
KR102522801B1 (ko) | 2023-04-19 |
EP3285109A1 (en) | 2018-02-21 |
HK1248828A1 (zh) | 2018-10-19 |
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