WO2016161990A3 - 用于治疗心血管疾病的固体制剂 - Google Patents

用于治疗心血管疾病的固体制剂 Download PDF

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Publication number
WO2016161990A3
WO2016161990A3 PCT/CN2016/090136 CN2016090136W WO2016161990A3 WO 2016161990 A3 WO2016161990 A3 WO 2016161990A3 CN 2016090136 W CN2016090136 W CN 2016090136W WO 2016161990 A3 WO2016161990 A3 WO 2016161990A3
Authority
WO
WIPO (PCT)
Prior art keywords
cardiovascular disease
solid preparation
treating cardiovascular
preparation used
enables
Prior art date
Application number
PCT/CN2016/090136
Other languages
English (en)
French (fr)
Other versions
WO2016161990A2 (zh
Inventor
蔡燕霞
王蓓
麦水梅
Original Assignee
深圳信立泰药业股份有限公司
山东信立泰药业有限公司
惠州信立泰药业有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳信立泰药业股份有限公司, 山东信立泰药业有限公司, 惠州信立泰药业有限公司 filed Critical 深圳信立泰药业股份有限公司
Publication of WO2016161990A2 publication Critical patent/WO2016161990A2/zh
Publication of WO2016161990A3 publication Critical patent/WO2016161990A3/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明提供了一种同时适用于硫酸氢氯吡格雷或阿利沙坦酯的包衣处方及包衣工艺，所述处方具有较现有技术具有更好的隔离效果，使得制剂在极端环境下亦可保持稳定，进而使得制剂在常规储存条件下可以实现更长时间的保存，有利于延长产品有效期。
PCT/CN2016/090136 2015-09-08 2016-07-15 用于治疗心血管疾病的固体制剂 WO2016161990A2 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510564484.7A CN105168166A (zh) 2015-09-08 2015-09-08 用于治疗心血管疾病固体制剂的包衣技术
CN201510564484.7 2015-09-08

Publications (2)

Publication Number Publication Date
WO2016161990A2 WO2016161990A2 (zh) 2016-10-13
WO2016161990A3 true WO2016161990A3 (zh) 2016-11-24

Family

ID=54890943

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2016/090136 WO2016161990A2 (zh) 2015-09-08 2016-07-15 用于治疗心血管疾病的固体制剂

Country Status (2)

Country Link
CN (2) CN105168166A (zh)
WO (1) WO2016161990A2 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168166A (zh) * 2015-09-08 2015-12-23 深圳信立泰药业股份有限公司 用于治疗心血管疾病固体制剂的包衣技术
CN108420798B (zh) * 2017-02-15 2021-03-02 江苏威凯尔医药科技有限公司 一种抗凝剂的速释药物制剂及其制备方法
US11478432B2 (en) 2018-04-16 2022-10-25 Jiangsu Vcare Pharma Tech Co., Ltd. Instant release pharmaceutical preparation of anticoagulant and preparation method therefor
CN115212180B (zh) * 2022-09-03 2024-05-10 深圳市信宜特科技有限公司 一种阿司匹林和硫酸氢氯吡格雷的复方制剂及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110189245A1 (en) * 2008-09-25 2011-08-04 Terzian Lana L Smooth, High Solids Tablet Coating Composition
CN103768063A (zh) * 2012-10-19 2014-05-07 深圳信立泰药业股份有限公司 一种盐酸莫西沙星药物组合物及其制备方法
CN103893773A (zh) * 2014-04-04 2014-07-02 成都科特包衣技术有限公司 一种耐油性胃溶型薄膜包衣预混辅料及其制备方法
CN105168166A (zh) * 2015-09-08 2015-12-23 深圳信立泰药业股份有限公司 用于治疗心血管疾病固体制剂的包衣技术

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2878748B1 (fr) * 2004-12-07 2007-03-09 Arrow Generiques Soc Par Actio Formule de comprimes permettant une liberation prolongee d'indapamide apres administration par voie orale et procede de preparation
CN101690719A (zh) * 2007-07-01 2010-04-07 深圳信立泰药业股份有限公司 一种硫酸氢氯吡格雷的固体制剂、其颗粒及其制备方法
CN100581547C (zh) * 2007-12-18 2010-01-20 严洁 一种雷诺嗪缓释片
CN102247333A (zh) * 2010-05-18 2011-11-23 山东方明药业股份有限公司 一种硫酸氢氯吡格雷片及其制备方法
US9555001B2 (en) * 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110189245A1 (en) * 2008-09-25 2011-08-04 Terzian Lana L Smooth, High Solids Tablet Coating Composition
CN103768063A (zh) * 2012-10-19 2014-05-07 深圳信立泰药业股份有限公司 一种盐酸莫西沙星药物组合物及其制备方法
CN103893773A (zh) * 2014-04-04 2014-07-02 成都科特包衣技术有限公司 一种耐油性胃溶型薄膜包衣预混辅料及其制备方法
CN105168166A (zh) * 2015-09-08 2015-12-23 深圳信立泰药业股份有限公司 用于治疗心血管疾病固体制剂的包衣技术

Also Published As

Publication number Publication date
CN105168166A (zh) 2015-12-23
CN107213131A (zh) 2017-09-29
WO2016161990A2 (zh) 2016-10-13

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