WO2016137131A3 - 연질 캡슐 조성물 - Google Patents

연질 캡슐 조성물 Download PDF

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Publication number
WO2016137131A3
WO2016137131A3 PCT/KR2016/000999 KR2016000999W WO2016137131A3 WO 2016137131 A3 WO2016137131 A3 WO 2016137131A3 KR 2016000999 W KR2016000999 W KR 2016000999W WO 2016137131 A3 WO2016137131 A3 WO 2016137131A3
Authority
WO
WIPO (PCT)
Prior art keywords
soft capsule
present
film
agent
long time
Prior art date
Application number
PCT/KR2016/000999
Other languages
English (en)
French (fr)
Other versions
WO2016137131A2 (ko
Inventor
김재훈
Original Assignee
김재훈
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 김재훈 filed Critical 김재훈
Publication of WO2016137131A2 publication Critical patent/WO2016137131A2/ko
Publication of WO2016137131A3 publication Critical patent/WO2016137131A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

본 발명은, 피막 형성제로서 수용성 셀룰로오스 에테르, 겔화제로서 이오타카라기난, 겔화보조제로서 유기계 칼슘염, 가소제로서 글리세린, 붕해촉진제로서 이산화규소 및 정제수를 포함하여 이루어지는 연질 캡슐 조성물에 관한 것이다. 본 발명에 따르면 연질 캡슐을 성형할 때에, 피막용액의 겔화 온도가 낮아져 에너지가 절감되며, 피막용액을 장시간 보관하여도 탄성을 갖는 습윤필름을 제조할 수 있어 장시간 성형 작업을 할 수 있게 된다. 이에 따라 연질 캡슐의 성형 작업성이 향상된다. 또한, 본 발명에 따르면 탄성이 우수하면서도 붕해성도 우수한 연질 캡슐을 제공할 수 있다.
PCT/KR2016/000999 2015-02-27 2016-01-29 연질 캡슐 조성물 WO2016137131A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150028040A KR101550322B1 (ko) 2015-02-27 2015-02-27 연질 캡슐 조성물
KR10-2015-0028040 2015-02-27

Publications (2)

Publication Number Publication Date
WO2016137131A2 WO2016137131A2 (ko) 2016-09-01
WO2016137131A3 true WO2016137131A3 (ko) 2016-10-20

Family

ID=54247334

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/000999 WO2016137131A2 (ko) 2015-02-27 2016-01-29 연질 캡슐 조성물

Country Status (2)

Country Link
KR (1) KR101550322B1 (ko)
WO (1) WO2016137131A2 (ko)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08208458A (ja) * 1994-12-01 1996-08-13 Nippon Eranko Kk カプセル用皮膜組成物
KR20020059329A (ko) * 1999-07-07 2002-07-12 알.피.쉐러 테크놀러지즈 인코포레이티드 개질 전분 및 이오타(ｉｏｔａ)-카라기난을 포함하는 필름 형성 조성물 및 그것을 이용한 연질 캡슐의 제조 방법
KR101342486B1 (ko) * 2005-03-11 2013-12-19 아르테르곤 에스.에이. 신규한 연질 젤라틴 캡슐
KR101445334B1 (ko) * 2013-06-05 2014-10-01 코스맥스바이오 주식회사 화학적 금속염을 포함하지 않는 식물성 연질캡슐조성물
KR101467853B1 (ko) * 2014-04-01 2014-12-03 창성소프트젤 주식회사 탄성 및 접착성이 우수하고 얇은 피막으로 생산성과 붕해도가 향상되는 식물성 연질캡슐 및 그의 조성물과 그 제조방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08208458A (ja) * 1994-12-01 1996-08-13 Nippon Eranko Kk カプセル用皮膜組成物
KR20020059329A (ko) * 1999-07-07 2002-07-12 알.피.쉐러 테크놀러지즈 인코포레이티드 개질 전분 및 이오타(ｉｏｔａ)-카라기난을 포함하는 필름 형성 조성물 및 그것을 이용한 연질 캡슐의 제조 방법
KR101342486B1 (ko) * 2005-03-11 2013-12-19 아르테르곤 에스.에이. 신규한 연질 젤라틴 캡슐
KR101445334B1 (ko) * 2013-06-05 2014-10-01 코스맥스바이오 주식회사 화학적 금속염을 포함하지 않는 식물성 연질캡슐조성물
KR101467853B1 (ko) * 2014-04-01 2014-12-03 창성소프트젤 주식회사 탄성 및 접착성이 우수하고 얇은 피막으로 생산성과 붕해도가 향상되는 식물성 연질캡슐 및 그의 조성물과 그 제조방법

Also Published As

Publication number Publication date
KR101550322B1 (ko) 2015-09-04
WO2016137131A2 (ko) 2016-09-01

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