WO2016080796A3 - 세스퀴테르펜 화합물을 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 및 이의 용도 - Google Patents
세스퀴테르펜 화합물을 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 및 이의 용도 Download PDFInfo
- Publication number
- WO2016080796A3 WO2016080796A3 PCT/KR2015/012504 KR2015012504W WO2016080796A3 WO 2016080796 A3 WO2016080796 A3 WO 2016080796A3 KR 2015012504 W KR2015012504 W KR 2015012504W WO 2016080796 A3 WO2016080796 A3 WO 2016080796A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mediated diseases
- preventing
- pharmaceutical composition
- sesquiterpene compound
- stat3
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
본 발명은 세스퀴테르펜 화합물을 포함하는 STAT3 매개 질환의 예방 또는 치료용 약학적 조성물 및 상기 조성물을 이용한 STAT3 매개 질환의 치료 방법에 관한 것이다. 또한, 본 발명은 세스퀴테르펜 화합물을 포함하는 STAT3 매개 질환의 예방 또는 개선용 식품 조성물, 의약외품 조성물, 사료 및 사료첨가제에 관한 것이다.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20140161605 | 2014-11-19 | ||
KR10-2014-0161605 | 2014-11-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016080796A2 WO2016080796A2 (ko) | 2016-05-26 |
WO2016080796A3 true WO2016080796A3 (ko) | 2016-10-06 |
Family
ID=56014656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2015/012504 WO2016080796A2 (ko) | 2014-11-19 | 2015-11-19 | 세스퀴테르펜 화합물을 포함하는, stat3 매개 질환의 예방 또는 치료용 약학적 조성물 및 이의 용도 |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR101741017B1 (ko) |
WO (1) | WO2016080796A2 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107805233B (zh) * | 2017-10-30 | 2020-07-28 | 浙江工业大学 | 一种二聚倍半萜化合物及其制备方法与应用 |
KR102074575B1 (ko) * | 2018-04-17 | 2020-02-06 | 원광대학교산학협력단 | 세스퀴테르펜 계열 대사체를 포함하는 항염증 조성물 |
CN111892563B (zh) * | 2020-08-26 | 2022-12-09 | 河南中医药大学 | 化合物3β-acetoxyl-atractylenolide I、制备方法和用途 |
CN113831221B (zh) * | 2021-09-18 | 2023-04-07 | 云南民族大学 | 一种倍半萜类化合物及其制备方法与应用 |
CN114956974B (zh) * | 2022-06-02 | 2023-10-31 | 暨南大学 | 一类倍半萜聚酮化合物、药物组合物及其用途 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20040107185A (ko) * | 2003-06-13 | 2004-12-20 | 이상국 | 알란토락톤 또는 이소알란토락톤을 포함하는 암 또는염증질환 예방 및 치료용 조성물 |
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2015
- 2015-11-19 WO PCT/KR2015/012504 patent/WO2016080796A2/ko active Application Filing
- 2015-11-19 KR KR1020150162645A patent/KR101741017B1/ko active IP Right Grant
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20040107185A (ko) * | 2003-06-13 | 2004-12-20 | 이상국 | 알란토락톤 또는 이소알란토락톤을 포함하는 암 또는염증질환 예방 및 치료용 조성물 |
Non-Patent Citations (4)
Title |
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FU, XIU - QIONG: "Inhibition of STAT3 Signalling contributes to the Antimelanoma Action of Atractylenolide II.", EXPERIMENTAL DERMATOLOGY, vol. 23, no. 11, 24 July 2014 (2014-07-24), pages 855 - 857, XP055317353 * |
LI, ER - WEI ET AL.: "New Eremophilenolides from Cacalia Pilgeriana.", PLANTA MEDICA, vol. 71, no. 12, 2005, pages 1140 - 1144, XP055317355 * |
MATSUURA, BRYAN S. ET AL.: "Intercepting Wacker Intermediates with Arenes: C-H Functionalization and Dearomatization.", ORGANIC LETTERS, vol. 13, no. 23, 2011, pages 6320 - 6323, XP055317358 * |
PANDEY, UMESH C. ET AL.: "Isoalantolactone Derivatives and Germacranolides from Blumea Densiflora.", PHYTOCHEMISTRY, vol. 24, no. 7, 1985, pages 1509 - 1514, XP026680004 * |
Also Published As
Publication number | Publication date |
---|---|
KR101741017B1 (ko) | 2017-05-30 |
KR20160060580A (ko) | 2016-05-30 |
WO2016080796A2 (ko) | 2016-05-26 |
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