WO2016076754A1

WO2016076754A1 - Semi-finished product for producing a feed additive

Info

Publication number: WO2016076754A1
Application number: PCT/RU2015/000681
Authority: WO
Inventors: Наталья Алексеевна КОЗЛОВА; Александр Александрович СВЯТКОВСКИЙ; Александр Владимирович СВЯТКОВСКИЙ; Ирина Владимировна ЛУНЕГОВА; Надежда Николаевна ПАВЛЮШИНА; Катерина Михайловна ТИХОНОВА; Андрей Юрьевич НЕЧАЕВ
Original assignee: Наталья Алексеевна КОЗЛОВА
Priority date: 2014-11-11
Filing date: 2015-10-16
Publication date: 2016-05-19
Also published as: RU2014145389A; RU2588645C2

Abstract

The present invention relates to veterinary science and can be used in the preparation of feeds for farm animals and birds, when it is most important to exactly follow a recipe in producing feed additives for same, with the possibility to quickly adjust the recipe so as to achieve a maximum decrease in the negative effect of toxins on health and productivity. A semi-finished product for producing a feed additive contains expanded vermiculite, having active components introduced into same, said active components including lactic acid with polyvinylpyrrolidone in an overall ratio of 3:2, and mycelium biomass in a ratio of 0.1-10:1 relative to the previous ratio. The technical result of the claimed invention consists in creating a novel, enlarged composite active and functional ingredient, namely, a semi-finished product for producing a feed additive for productive farm animals and birds, wherein said ingredient can also be used independently and, in addition, can be stored for a long time in order to be subsequently used in a process for producing another corresponding feed additive, providing for the precisely calibrated use of ingredients in the final product and increasing the manufacturability of said ingredients.

Description

SEMI-FINISHED PRODUCT FOR PRODUCING FODDER ADDITIVE

FIELD OF TECHNOLOGY

The present invention relates to veterinary medicine and can be used in the preparation of feed for farm animals and birds, when it is most important to strictly comply with the formulation of the feed additives obtained for them with the possibility of its rapid change in order to achieve the maximum reduction in the negative impact of toxins on their health and productivity.

BACKGROUND

As you know, high productivity means the genetically determined ability of animals to transform feed nutrients into elements of tissues, organs, and productive secrets that are used as food products or technological raw materials. But for all the genetic potential to be realized, it is necessary to observe a large list of conditions and quality of performance, such as: in feeding, keeping, exercise, etc. One of the most important conditions for the productivity of animals and birds is a complete and balanced feeding. It is known that with modern intensification and cheaper In livestock and poultry production, often insufficient quality of feed is used, both in the content of nutrient ingredients (deficiency) and in the content of harmful substances (the presence of toxins, pesticides, heavy metals, etc.). Poor feeding leads to an increase in the total load on the body of an animal or bird, which is further expressed in the occurrence of diseases of various etiologies, poisoning, stress and, as a result, a decrease in productivity and quality of manufactured products. Currently, the presence of toxins (mycotoxins) in animal and bird feed is almost inevitable, for the neutralization and elimination of the body of which experts use various drugs, for example: antioxidants, enzymes, organic and inorganic sorbents, etc.

Currently, the most commonly used means to protect animals from the damaging effects of contaminated feeds are the use of mycotoxin-binding sorbents. The action of sorbents is based on the ability to bind and remove mycotoxins from the gastrointestinal tract. Sorbents must quickly bind and effectively retain mycotoxins at various levels of acidity of the gastrointestinal tract and the rate of removal of residual metabolic products from it, including mycotoxins.

The negative quality of the sorbent materials is their low specificity, which results in the binding of nutrients (essential fatty acids, vitamins, amino acids) and drugs (Disinfection of mycotoxins in animal feed with various adsorbents, Toxicology Letters, 122 (2001), 179-188).

The use of organic acids with pronounced bactericidal activity is known. In recent years, developed highly effective preparations based on organic acids, which have a bactericidal, antiseptic and fungicidal effect (Instructions for use Cuxacid S, LOMAN ANIVAL HELTH, Germany). They can effectively preserve feed and destroy the already formed toxins. In addition, many acids (succinic, lactic) stimulate the protective functions of the body and improve digestion.

The disadvantage of such drugs is the use of active acids such as formic and acetic acids, which at high dosages can lead to acidosis. Concentration, which is not sufficient to kill mold due to a change in the pH of the medium, can create stress for molds, which, in turn, stimulates the formation of toxins.

It is known to use a chitin-chitosan complex with sorption and denitrifying properties, which removes mainly radionuclides, heavy metals, nitrates and nitrites from animals and birds, which ultimately positively affects the health of the animal and bird and their productivity. The source of the chitin-chitosan complex in feeding is mainly shell rock or mushrooms. It is known to use the biomass of fungal mycelium as a source of chitin-chitosan complex for the detoxification effect on the animal organism.

The disadvantage of this product is the need to enter a large amount of mycelium into the diet for a theoretical full anti-toxic effect. But when a large amount of mushroom mycelium biomass is added to the diet, there will be an imbalance in the composition of the feed with respect to useful and nutrients, as a result - a violation of the feeding technology.

Famous FODDER PRODUCT FOR PRODUCTIVE AGRICULTURAL ANIMALS AND BIRDS (see Patent R.F. _/

4 JJO /. The log feed product contains aluminosilicate as a sorptive material and additionally includes a silver complex with polyvinylpyrrolidone, lactic acid, succinic acid or its salts, citric acid and iodine in the following ratio of ingredients, wt.%: lactic acid - 8.0-12.0 succinic acid (or its salts) - 2.0-5.0 citric acid - 5.0-12.0 polyvinylpyrrolidone - 5.0-8.0 silver - 0.0001-0.0002 iodine - 0.005-0.01 aluminosilicate - the rest is up to 100%

This known feed product is prepared as follows.

1. Take purified water corresponding to Purified Water SanPiN 2.1.4.1074-01, GOST R 51232 and serve in an ionizer in which it is saturated with silver to a concentration of 2-25 mg / liter;

2.3 then in a blending vessel polyvinylpyrrolidone (PVP) is mixed with ionized water;

But

3. Then the PVP solution with silver enters mixer 1 and the liquid fractions of organic acids enter the same. All this is mixed with aluminosilicates, characterized by sorption properties: water capacity 320-468%, fat capacity 208-324%; „

4. i3 mixer product enters the oven to remove excess moisture;

5. From the oven, the mixture enters the mixer ^ ^s 2, where the final mixing takes place with organic acids and an aluminosilicate filler;

6. From the mixer 2, the finished product enters the packaging and labeling line.

This well-known feed product is already used to neutralize toxins in the feed and gastrointestinal tract of highly productive animals and birds. Its composition includes only natural components that do not have negative side effects on the animal’s body in acceptable concentrations. It performs the following functions: inhibits the development and destroys existing toxins, improves the detoxification function of the liver. The presence of mycotoxins in feed leads to a decrease in productivity, reproductive qualities and the immune state of animals. Although mycotoxins differ in chemical structure, toxicity and mechanism of action, the main sign of all mycotoxins is toxicity relative to eukaryotic organisms.

From the analysis of the formulas and descriptions of the known invention in the technology of its production, it can be distinguished that in this composition they use semi-finished product - aluminosilicates, since they are used in a sufficiently large amount as feedstock. Then they add lactic acid and all other active components to them and, in a continuous process, mix, getting the final product - a feed mixture. But the source is a semi-finished product that contains expanded vermiculite. UH has the following disadvantages: low specificity, as a result of which the binding of nutrients (essential fatty acids, vitamins, amino acids) and drugs (Mycotoxin neutralization in animal feed by various adsorbents, Toxicology Letters, 122 (2001), 179-188).

This semi-finished product is selected as a prototype, since it contains the largest number of essential features matching the essential features of the claimed invention.

SUMMARY OF THE INVENTION

The objective of the present invention is the creation of a new semi-finished product, which has the following technical result, namely: high selectivity of specific sorption and neutralization of various substances in the body of an animal and bird, in particular in the gastrointestinal tract. And also allows you to be a new enlarged composite active functional component to obtain a feed additive.

The problem is solved as follows. In the known semi-finished product, including expanded vermiculite, according to the present invention, an active component is introduced, which is used lactic acid with polyvinylpyrrolidone in a total ratio of 3: 2 and the mycelium biomass of Aspergillus niger fungus in a ratio of 0.1-10: 1 to the previous ratio.

The proposed semi-finished product allows to achieve the following technical result: to increase the selectivity of specific sorption and neutralization of various substances in the body of an animal and bird, in particular in the gastrointestinal tract. This means that having very strong sorption properties, it has high selectivity - it enhances the neutralization and elimination of animal and bird from the body _m „„

the flow of ins, heavy metals, and even radionuclides coming in as feed, minimizing the sorption of nutrients and compounds, and also helps general detoxification, which improves the qualitative and quantitative indicators of the health of the animal or bird and the resulting product. The semi-finished product can be independently used as a feed mixture.

This result is achieved due to the fact that during the preparation of a semifinished product in the process of layer-by-layer deposition of sorbents and neutralizers (organic acids and a chitin-chitosan complex) of toxins on a known semifinished product - expanded vermiculite, micropores of aluminosilicate are filled with them and the molecular binding to it is not stable level. When a semi-finished product enters the gastrointestinal tract of an animal or bird, other sorbents and neutralizers (organic acids and chitin-chitosan complex) that are involved in detoxification of the body not only directly into the gastrointestinal tract, but also get into the bloodstream, neutralize and remove toxins, separated from vermiculite. some heavy metals and radionuclides in the entire macroorganism. Expanded free vermiculite binds toxins and heavy metals that come with food and are in the digestive tract, forming a strong complex, thereby neutralizing them, removes them from the body in a natural way with feces.

This technical result of the proposed semi-finished product is also due to the technology of preparing the semi-finished product as an independent product. Namely, the semi-finished product is made by mixing about 80% lactic acid solution with polyvinylpyrrolidone 1: 0.02, and then the resulting mixture is sprayed onto expanded vermiculite in a ratio of 2: 3 to obtain a dry and free-flowing mixture. To the resulting mixture add the biomass of the mycelium of the fungus Aspergillus niger (npeflno4THTenbHO according to TU 9291-001-00343237-2000, but others are also suitable options, for example, according to T TU r 9v2> n9i1- l00l2- l00l4 and t7l9l9l94 _/! -95, and others. L) in a ratio of 0.1-10: 1.

The applicant conducted a patent search, which showed that the proposed set of technical features is unknown. Therefore, this invention can be considered new.

The proposed semi-finished product has an inventive step, since the proposed combination of its essential features for a specialist does not logically follow from the prior art.

However, each component is individually known and their use as independent ingredients for the preparation of feed additives does not need to be explained. But the technology of taring these sorbents and their ratio in the semi-finished product allows you to get a completely new adsorbent and toxin neutralizer with a wide range of functionality of the three known and used drugs (aluminosilicates, organic acids, chitin-chitosan complex). A successful combination of ingredients and the method of preparation of the semi-finished product allows you to get a product with the maximum pronounced antitoxic effect at low dosages and is a good basis for feed products.

DETAILED DESCRIPTION OF THE INVENTION

The practical application of the invention is disclosed in the following description with illustrative examples.

1) Prefabricated to obtain a feed additive. For its preparation, the following components are used: lactic acid, polyvinylpyrrolidone, expanded vermiculite in a total ratio of 2: 0.04: 3; mycelial biomass in a ratio of 0.1-10: 1 to the previous ratio. „ _C

1.1) JD lactic acid solution Sir / o added polyvinylpyrrolidone (liquid viscous mass) in a ratio of 1: 0.02 and stirred until a homogeneous liquid.

1.2) Then they took three parts of expanded vermiculite and sprayed on it two parts of a previously prepared homogeneous liquid n 1.1.

1.3) Then, the mycelium biomass in a ratio of 0.1-10: 1 was added to the resulting mixture of p 1.2, depending on the physiological needs and characteristics of the animal or bird organism.

1.4) The resulting mixture remains dry and free-flowing, evenly calibrated, manufactured and stored in a separate container, and can also go immediately to the preparation of a feed additive.

A known method of adding liquid fractions to a feed additive in the prototype (patent N ° RU 2 425 587 C1), but the process is integral to the technology for the production of feed additives and requires additional drying of the raw material.

A known method of using vermiculite with organic acids in the prototype (patent N ° RU 2 425 587 C1) and in others, in particular with lactic acid for the conservation of feed and their storage. Our semi-finished product can also be used for preserving feed, but it is more technologically advanced in production and is more functional in the sorption and neutralization of toxins, heavy metals and radionuclides in the body of animals and birds. The difference in the applied ratio of mycelium biomass to vermiculite with lactic acid according to p. 1.2 is determined when preparing a semi-finished product depending on the physiological characteristics and condition of animals and birds.

For example: with the addition of a semi-finished product, where the ratio of mycelium biomass to vermiculite with lactic acid according to item 1.2 5: 1, in the diet of cattle 100 g per head per day, the excretion of toxins, heavy metals, nitrates and nitrites from the animal’s body significantly increases with food; eatability of feed improves; stimulated by liver function (its detoxification abilities) and carbohydrate oomen in the body, which improves the quality of the final product obtained and increases its quantity.

For example: when adding a semi-finished product, where the ratio of mycelium biomass to vermiculite with lactic acid according to item 1.2 0.1: 1, to the diet of poultry (laying hens) 1 kg per ton of feed, the excretion of toxins, heavy metals, nitrates from the animal’s body significantly increases and nitrites supplied with feed; eatability of feed improves; liver function (its detoxification abilities) and carbohydrate metabolism in the body are stimulated, which improves the quality of the final product obtained and increases its quantity.

Thus, the technical result of the claimed invention is achieved: the creation of a new enlarged composite active and functional component, such as a semi-finished product for producing a feed additive for productive farm animals and birds, which also has independent use and at the same time can be stored for a long time for subsequent use .. In the process of preparing the next appropriate feed additive, it provides accurate calibrated use of components in the final product, and increases manufacturability of their preparation. The semi-finished product increases the selectivity of specific sorption and neutralization of various toxins in the body of an animal and bird, in particular in the gastrointestinal tract - it enhances the neutralization and elimination of toxins, heavy metals and even radionuclides from the body of an animal and bird, minimizing the sorption of nutrients and compounds , and also helps general detoxification, which improves the qualitative and quantitative indicators of the health of the animal or bird and the resulting product.

Claims

Claim

1. The semi-finished product for the feed additive contains expanded vermiculite, characterized in that an active component is introduced, which is used lactic acid with polyvinylpyrrolidone in a total ratio of 3: 2 and mycelium biomass in a ratio of 0.1-10: 1 to the previous ratio.