WO2016055483A1 - Produit de soin de plaies présentant un non-tissé en nanofibres - Google Patents

Produit de soin de plaies présentant un non-tissé en nanofibres Download PDF

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Publication number
WO2016055483A1
WO2016055483A1 PCT/EP2015/073059 EP2015073059W WO2016055483A1 WO 2016055483 A1 WO2016055483 A1 WO 2016055483A1 EP 2015073059 W EP2015073059 W EP 2015073059W WO 2016055483 A1 WO2016055483 A1 WO 2016055483A1
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WO
WIPO (PCT)
Prior art keywords
wound
care product
product according
wound care
layers
Prior art date
Application number
PCT/EP2015/073059
Other languages
German (de)
English (en)
Inventor
Birgit Riesinger
Original Assignee
Bsn Medical Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bsn Medical Gmbh filed Critical Bsn Medical Gmbh
Publication of WO2016055483A1 publication Critical patent/WO2016055483A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Definitions

  • Wound care product comprising a nanofiber nonwoven
  • the present invention relates to a wound care product comprising a nanofiber nonwoven according to the preamble of claim 1.
  • wound care products are based on cellulose and may be supplemented with other materials.
  • Cellulose for example, has poor wicking behavior and is therefore difficult to control, so wound care products tend to fix ingested moisture in place, which in turn can cause macerations of the wound edges.
  • cellulose can, under certain circumstances, provide a favorable environment for the growth of bacteria. Furthermore, cellulose has a certain hardness at the fiber level, which can be perceived as uncomfortable by patients.
  • Polyurethane often soft and cushioning, but still stiff and rigid. They only absorb comparatively little liquid and often leave them free to pressure from the outside. This leads to a high alternating frequency, which in turn is high
  • composition of such foam dressings usually consists of materials which only absorb and cushion liquids which, however, lack further functional properties.
  • a wound care product comprising at least one flat layer comprising a nanofiber nonwoven is provided,
  • nanofibers as used herein means fine fibers of polyurethanes having a diameter of less than 10 ⁇ m, often less than 1 ⁇ m.
  • nanofiber nonwovens are described, for example, in US Pat. 4,043,331 and WO 01/27365. They have great flexibility, adaptability and softness, and are also capable of effectively draining liquids. It is preferably provided that the nanofibers are fibers comprising polyurethane.
  • the fibers may also comprise cellulose or its derivatives, polyamides, polyesters, polyacrylonitriles, polyvinyl alcohols, polyvinylpyrrolidones, polyethylene oxides, cellulose acetates, polyethyleneimines, polycaprolactones or poly-2-hydroxymethacrylates, or mixtures or copolymers
  • At least one of the laminar layers comprising a nanofiber nonwoven fabric has a hydrophilic TPU nanofiber matrix.
  • TPU refers to urethane-based thermoplastic elastomers which have a foam-like consistency similar to a high-grade polyurethane foam and are described, for example, by the company SNS Nano Fiber Technology, Hudson, OH under the term Nanosan® Nanosan - sorb marketed.
  • this material Compared to cellulose, this material has a well-controlled "wicking" behavior, which prevents maceration, for example, and unlike cellulose, it also provides an unfavorable growth environment.
  • this material has a great softness, which is perceived by patients as unpleasant. This is accompanied by a particularly high degree of flexibility and / or a particularly low rigidity, which allows the wound care product to adapt well to the wound contour.
  • the material Compared with foam dressings, the material has a lower stiffness and rigidity. Furthermore, unlike foams, the material can be functionalized in a wide variety of ways.
  • At least one of the flat layers additionally comprises superabsorbent polymers.
  • Superabsorbent polymers are plastics that are able to absorb many times their own weight - up to 1000 times - in liquids. Chemically, this is a copolymer of acrylic acid (propionic acid, C3H4O2) and sodium acrylate (sodium salt of acrylic acid, NaCsFbC), wherein the ratio of the two monomers may vary.
  • a so-called core crosslinker core-crosslinker, CXL
  • CXL core-crosslinker
  • the superabsorbent polymers can be present in the wound care product according to the invention in the form of a granulate, a powder, a bed, a compact, a foam, in the form of fibers, a fiber knitted, laid or nonwoven fabric and / or a fiber wadding.
  • the methylacrylic acid-based superabsorbents polyvinyl alcohol-maleic anhydride copolymers, polysaccharide-maleic anhydride copolymers, maleic acid derivatives, acrylamidopropanesulfonic acid copolymers, starch acrylonitrile graft polymers, gelatinized starch derivatives, alkyl or hydroxyalkyl cellulose, carboxymethyl cellulose, starch acrylic acid graft polymers, vinyl acetate acrylic acid esters - Copolymers, acrylonitrile or acrylamide copolymers may be selected.
  • the superabsorber particles can be present in powder or granular form in an average particle size between 10 and 2000 ⁇ m. They may also be in fibrous form. Also, mixtures of the aforementioned embodiments are conceivable.
  • Superabsorbent polymers in particular based on polyacrylates, have germ-binding properties, and moreover are capable of deactivating germs by ionic interactions, dehydration and other, as yet unclarified, effects.
  • a suitably equipped wound care product according to the invention can therefore bring about a reduction in the number of germs in the wound even without delivery of pharmaceutical substances.
  • the patent applicant has conducted extensive experiments.
  • superabsorbent polymers particularly those based on polyacrylates, have protein binding properties, and thus can accomplish the uptake of bacterial endotoxins, wound damaging proteases such as MMPs and cytokines such as interleukins or tumor necrosis factors.
  • the wound care product has two or more laminar layers comprising a nanofiber nonwoven, wherein at least two of these have a different grammage and / or a different SAP content.
  • At least one of the sheet-like layers has a grammage in the range between> 150 g / m 2 and ⁇ 500 g / m 2 .
  • the grammage is preferably 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370 , 380, 390, 400, 410, 420, 430, 440, 450, 460, 470, 480, 490 or 500 g / m 2 +/- 5 g / m 2 .
  • At least one of the flat layers has a grammage in the range between> 30 g / m 2 and ⁇ 250 g / m 2 .
  • the grammage is preferably 30, 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, or 250 g / m 2 +/- 5 g / m 2 .
  • At least one of the sheet-like layers has an SAP content between> 30% by weight and ⁇ 95% by weight.
  • the SAP content is preferably 30, 32.5, 35, 37.5, 40, 42.5, 45, 47.5, 50, 52.5, 55, 57.5, 60, 62.5, 65, 67.5, 70, 72.5, 75, 77.5, 80, 82.5 , 85, 87.5, 90, 92.5, 95, 97.5, or 100 +/- 2.5 parts by weight Likewise, it is preferably provided that at least one of the two-dimensional layers has an SAP content of between> 0% and ⁇ 40% by weight.
  • the SAP content is preferably 0, 2.5, 5, 7.5, 10, 12.5, 15, 17.5, 20, 22.5, 25, 27.5, 30, 32.5, 35, 37.5, or 40 +/- 2.5% by weight.
  • the wound care product has a sandwich-like arrangement of the at least two flat layers, as well as a sore-facing and a sore-facing flat side, the layer having the lower grammage and / or the lower SAP content being arranged on the wound-facing side.
  • the wound care product has a sandwich-like arrangement with at least three flat layers, wherein an inner layer has a relatively higher grammage and / or a relatively higher SAP content and two respective outer layers have a relatively lower grammage and / or a relative have lower to absent SAP content.
  • the wound care product further has a sore-facing and a sore-facing flat side, the sore-facing side having a liquid-impermeable and / or elastic backsheet
  • Said backsheet can be designed in particular color. It may also have a rough or smooth surface to either have an attractive handle or to be worn under clothing without further complications.
  • the backsheet can furthermore preferably be made germ-proof in order to be able to prevent the emergence of germs. For this purpose, a maximum pore size of about 0.2 ⁇ - 1 ⁇ be provided.
  • the backsheet can be present as a textile nonwoven, foil, or nonwoven. Said backsheet can be designed in particular vapor permeable. It can be provided that the Water Vapor Transmission Rate (WVTR) is in the range between> 4000 gr / m 2 day and ⁇ 15,000 gr / m 2 day. In this way it is ensured that under said backsheet no moisture build-up or sweating, while a moisture leakage is still prevented.
  • WVTR Water Vapor Transmission Rate
  • the wound care product has an adhesive layer, which is arranged at least in sections on the wound-facing surface side.
  • the edge of at least one of the laminar layers comprising a nanofiber nonwoven be edged and / or sealed.
  • This may be useful, especially for SAP-containing layers, to prevent leakage of swollen SAP material. Although this is not toxic to the wound, and otherwise physiologically harmless, but it can be as an increased cleaning effort and possibly also a contamination of the environment with pathogenic germs are prevented.
  • the enclosure is formed from the material of the backsheet and / or from the material of the adhesive layer, for example in the form of a piping, which is formed partly from the material of the backsheet and partly from the material of the adhesive layer.
  • the adhesive layer has at least one physiologically acceptable adhesive selected from the group consisting of silicone, HydrokoUoid, or acrylate.
  • the adhesive layer comprises an adhesive laminate having a first, lying on the skin distal adhesive layer based on acrylate, a carrier layer, and a second, proximal to the skin continuous silicone-based adhesive layer.
  • the adhesive layer can be arranged like a frame only in the periphery of the wind care product, or even this inferior on the wound-facing side more or less entirely. In the latter case, it can preferably be provided that the adhesive layer has pores or punctures at least in the central region, which facilitate an exudate passage.
  • the adhesive layer has a larger area than the underlying absorbent layer.
  • the backsheet and / or at least one layer comprising a nanofiber nonwoven fabric is designed elastically deformable.
  • the wound care product can exploit its full absorption capacity and, moreover, can adapt to complicated wound geometry and / or contours.
  • the wound care product contains at least one wound-healing-promoting additive.
  • This may be, for example, a substance selected from the group DHMB, heavy metal or heavy metal ions (silver, copper, Zionk), honey or honey extracts, detergents, disinfectants such as octenidine, antibiotics, polyhexanide, antibacterial peptides and / or antibiotics.
  • the wound care product according to the invention has a microabrasive surface facing the wound in order to promote the removal of wound cover.
  • a microabrasive surface facing the wound in order to promote the removal of wound cover.
  • Such a surface is designed in such a way that the wound care product is suitable for breaking up relative to a wound a) a biofilm arranged in the wound, and / or
  • Such a microabrasive surface can, for example
  • a cleaning body comprising an emulsion, a gel, a suspension, a paste or a dry product.
  • a material in particular a film, comprising a three-dimensional
  • the wound care product according to the invention has a wound spacer mesh, preferably a three-dimensional wound spacer mesh, facing the wound.
  • the wound care product has no shell.
  • the wound care product has a sheath which, for example by seams or fold edges, defines an inner surface 3% to 80% larger in plan view than the area of an absorbent layer disposed therein.
  • the inner absorbent layer is not limited in its absorption capacity by a constricting sheath.
  • the shell consists of two flat layers connected at the edges.
  • the shell can be configured identically on both sides, but also in such a way that the materials of the two planar layers are different
  • the wound care product is moistened or impregnated with an electrolyte.
  • a kit of parts comprising a wound care product according to one of the preceding claims and an electrolyte for moistening or impregnating the same
  • a cleaning and rinsing system is realized which, applied to the wound, removes pathological exudate and releases it to the wind against electrolyte, such as physiological saline or Ringer's solution.
  • electrolyte such as physiological saline or Ringer's solution.
  • coverings such as biofilms or fibrin coatings, softened and removed.
  • nanofibers for the preparation of a wound care product as described above for use - or the use of the wound care product itself - is intended for one of the following purposes:
  • nanofibers for the preparation of a wound care product as described above for use - or the use of the wound care product itself - is intended for one of the following purposes:
  • ⁇ as a secondary dressing, which can be arranged as a second dressing over a primary dressing, eg a spacer grid, or over a wound gel
  • a wound care product as described above is intended wherein it is moistened or soaked with electrolyte in the wound region.
  • FIG. 1 shows a wound care product comprising a sheet-like layer 1 comprising a nanofiber nonwoven fabric made of a hydrophilic TPU nanofiber matrix.
  • superabsorbent polymers 2 are additionally introduced.
  • the wound care product further has a side facing away from the wound, which is provided with a liquid-impermeable elastic backsheet 3.
  • the wound care product further comprises an adhesive layer 4 disposed on the wound facing flat side of the wound care product.
  • the Backsheet 3 is over the edges of the sheet-like layer 1 comprising a nanofiber nonwoven over.
  • the adhesive layer 4 is arranged like a frame only in the region of the periphery of the wind care product.
  • superabsorbent polymers were homogeneously dispersed in a polymer solution, which is then subjected to an electropulse process, whereby the superabsorbent polymers are homogeneously embedded in the nanofiber matrix.
  • FIG. 2 shows a similar wound care product, but having three sheet layers 5, 6, and 7 comprising a nanofiber web.
  • the two outer layers have a different grammage and a different SAP content than the inner layer.
  • Figure 3 shows a similar wound care product, but having an adhesive layer 4 disposed on the sore-facing sheet side of the wound care product covering the entire wound-facing side and having pores or punctures in the central area 8 facilitating exudate passage.
  • FIG. 4 shows a similar wound care product, in which the edge of the laminar layers comprising a nanofiber nonwoven is bordered.
  • the enclosure is formed from the material of the backsheet and the adhesive layer.
  • the edge area is filled with an adhesive 9 to fix the enclosure.
  • Fig. 5 shows a micrograph of a nanofiber web having superabsorbent polymers.
  • the wound care product according to the invention preferably has a higher affinity for protein-containing solutions than for saline-containing solutions.
  • the wound care product according to the invention preferably has a layer which exhibits a distinct extensibility in at least one direction.
  • the wound care product according to the invention has a layer with non-foamed polyurethane.
  • the wound care product according to the invention has a layer which contains between 3 and 95% by volume inclusive of SAP, preferably 3; 4; 5; 6; 7; 8th; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; 60; 61; 62; 63; 64; 65; 66; 67; 68; 69; 70; 71; 72; 73; 74; 75; 76; 77; 78; 79; 80; 81; 82; 83; 84; 85; 86; 87; 88; 89; 90; 91; 92; 93; 94 or 95%.
  • the wound care product according to the invention has a layer which contains between 3 and up to and including 95% by weight of SAP, preferably 3; 4; 5; 6; 7; 8th; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; 60; 61; 62; 63; 64; 65; 66; 67; 68; 69; 70; 71; 72; 73; 74; 75; 76; 77; 78; 79; 80; 81; 82; 83; 84; 85; 86; 87; 88; 89; 90; 91; 92; 93; 94 or 95%.
  • the wound care product according to the invention has a layer which comprises between 3 and up to and including 95% by weight of polyurethane, preferably 3; 4; 5; 6; 7; 8th; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; 60; 61; 62; 63; 64; 65; 66; 67; 68; 69; 70; 71; 72; 73; 74; 75; 76; 77; 78; 79; 80; 81; 82; 83; 84; 85; 86; 87; 88; 89; 90; 91; 92; 93; 94 or 95% by weight
  • the wound care product according to the invention has a layer which comprises between 3 and up to and including 95% by volume of polyurethane, preferably 3; 4; 5; 6; 7; 8th; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; 60; 61; 62; 63; 64; 65; 66; 67; 68; 69; 70; 71; 72; 73; 74; 75; 76; 77; 78; 79; 80; 81; 82; 83; 84; 85; 86; 87; 88; 89; 90; 91; 92; 93; 94 or 95% by volume
  • the wound care product according to the invention has a multi-layer structure of at least two layers, wherein the first layer is free of SAP, and the second layer contains at least 5 wt .-% SAP.
  • the wound care product according to the invention has a thickness (overall height) of between 1 and 10 mm inclusive, preferably 1; 2; 3; 4; 5; 6; 7; 8th; 9; 10 mm; more preferably between 2 and 4 mm inclusive, preferably 2.0; 2.1; 2.2; 2.3; 2.4; 2.4; 2.5 2.6; 2.7; 2.8; 2.9; 3.0; 3.1; 3.2; 3.3; 3.4; 3.5 3.6; 3.7; 3.8; 3.9 or 4.0 mm.
  • the wound care product according to the invention has a particularly high flexibility and / or a particularly low rigidity.
  • the wound care product according to the invention comprises dialkylcarbamoyl chloride or similar apolar substances.
  • the wound care product according to the invention is designed such that an inner layer has a greater affinity for absorbed fluid than a position facing away from the wound, so that the absorbed fluids only pass into the position away from the wound when the inner layer is saturated.
  • the wound care product according to the invention is designed such that at least one layer of the wound care product expands laterally on wetting and / or saturation and possibly throws wrinkles.

Abstract

L'invention concerne un produit de soin de plaies qui comprend au moins une couche plane présentant un non-tissé en nanofibres.
PCT/EP2015/073059 2014-10-06 2015-10-06 Produit de soin de plaies présentant un non-tissé en nanofibres WO2016055483A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102014114461 2014-10-06
DE102014114461.9 2014-10-06

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Publication Number Publication Date
WO2016055483A1 true WO2016055483A1 (fr) 2016-04-14

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Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4043331A (en) 1974-08-05 1977-08-23 Imperial Chemical Industries Limited Fibrillar product of electrostatically spun organic material
EP0341870A2 (fr) * 1988-05-13 1989-11-15 Minnesota Mining And Manufacturing Company Pansement absorbant élastomère pour blessure
WO2001027365A1 (fr) 1999-10-08 2001-04-19 The University Of Akron Fibres filees electriquement et appareil correspondant
WO2007118652A1 (fr) 2006-04-12 2007-10-25 Birgit Riesinger Pansement primaire
US20080255492A1 (en) * 2004-08-19 2008-10-16 Jens Hoeg Truelsen Absorbent Fiber Material and Use Thereof in Wound Dressings
EP2335743A2 (fr) * 2005-08-05 2011-06-22 Schill + Seilacher GmbH Nanofibreux non-tissé contenant de la poudre superabsorbante
EP2359784A1 (fr) * 2005-11-02 2011-08-24 Birgit Riesinger Corps d'absorption destiné à être appliqué sur la surface cutanée d'un être humain ou d'un animal
US20120070485A1 (en) * 2009-05-26 2012-03-22 Giorgio Soldani method for producing a device applicable to biological tissues, particularly a patch for treating damaged tissues, and a device obtained by said method
WO2013113906A1 (fr) 2012-02-01 2013-08-08 Birgit Riesinger Article pour le soin des plaies comprenant au moins une surface présentant des propriétés abrasives
WO2013121006A1 (fr) 2012-02-17 2013-08-22 Birgit Riesinger Pansement primaire perméable aux liquides et présentant une part de métal lourd
WO2014108476A1 (fr) 2013-01-09 2014-07-17 Birgit Riesinger Pansement primaire perméable aux liquides et revêtu de silicone

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4043331A (en) 1974-08-05 1977-08-23 Imperial Chemical Industries Limited Fibrillar product of electrostatically spun organic material
EP0341870A2 (fr) * 1988-05-13 1989-11-15 Minnesota Mining And Manufacturing Company Pansement absorbant élastomère pour blessure
WO2001027365A1 (fr) 1999-10-08 2001-04-19 The University Of Akron Fibres filees electriquement et appareil correspondant
US20080255492A1 (en) * 2004-08-19 2008-10-16 Jens Hoeg Truelsen Absorbent Fiber Material and Use Thereof in Wound Dressings
EP2335743A2 (fr) * 2005-08-05 2011-06-22 Schill + Seilacher GmbH Nanofibreux non-tissé contenant de la poudre superabsorbante
EP2359784A1 (fr) * 2005-11-02 2011-08-24 Birgit Riesinger Corps d'absorption destiné à être appliqué sur la surface cutanée d'un être humain ou d'un animal
WO2007118652A1 (fr) 2006-04-12 2007-10-25 Birgit Riesinger Pansement primaire
US20120070485A1 (en) * 2009-05-26 2012-03-22 Giorgio Soldani method for producing a device applicable to biological tissues, particularly a patch for treating damaged tissues, and a device obtained by said method
WO2013113906A1 (fr) 2012-02-01 2013-08-08 Birgit Riesinger Article pour le soin des plaies comprenant au moins une surface présentant des propriétés abrasives
WO2013121006A1 (fr) 2012-02-17 2013-08-22 Birgit Riesinger Pansement primaire perméable aux liquides et présentant une part de métal lourd
WO2014108476A1 (fr) 2013-01-09 2014-07-17 Birgit Riesinger Pansement primaire perméable aux liquides et revêtu de silicone

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