WO2015157768A1 - Implant delivery system - Google Patents

Implant delivery system Download PDF

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Publication number
WO2015157768A1
WO2015157768A1 PCT/US2015/025594 US2015025594W WO2015157768A1 WO 2015157768 A1 WO2015157768 A1 WO 2015157768A1 US 2015025594 W US2015025594 W US 2015025594W WO 2015157768 A1 WO2015157768 A1 WO 2015157768A1
Authority
WO
WIPO (PCT)
Prior art keywords
pusher
heater
coil
tether
wire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2015/025594
Other languages
English (en)
French (fr)
Inventor
Heath Bowman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MicroVention Inc
Original Assignee
MicroVention Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MicroVention Inc filed Critical MicroVention Inc
Priority to EP22201761.8A priority Critical patent/EP4151164A1/en
Priority to CN201580030683.8A priority patent/CN106659574B/zh
Priority to EP15777509.9A priority patent/EP3128961B1/en
Priority to JP2017504634A priority patent/JP6749888B2/ja
Publication of WO2015157768A1 publication Critical patent/WO2015157768A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12154—Coils or wires having stretch limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00026—Conductivity or impedance, e.g. of tissue
    • A61B2017/0003—Conductivity or impedance, e.g. of tissue of parts of the instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00929—Material properties isolating electrical current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205—Introduction devices
    • A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12068—Details concerning the detachment of the occluding device from the introduction device detachable by heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08—Accessories or related features not otherwise provided for
    • A61B2090/0807—Indication means
    • A61B2090/0808—Indication means for indicating correct assembly of components, e.g. of the surgical apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents

Definitions

  • the system comprises an implant, a delivery catheter (generically referred to as the pusher or delivery pusher), a detachable joint for coupling the implant to the pusher, a heat generating apparatus (generically referred to as the heater), and a power source to apply energy to the heater.
  • a delivery catheter generically referred to as the pusher or delivery pusher
  • a detachable joint for coupling the implant to the pusher
  • a heat generating apparatus generatorically referred to as the heater
  • a power source to apply energy to the heater.
  • Figure 4 illustrates a cross-sectional side view of a third embodiment of a detachment system according to the present invention.
  • Figure 15 illustrates a perspective view of the delivery system of Figure 13
  • Figure 18 illustrates a side view of an alternate tether arrangement for the delivery system of Figure 13.
  • Figures 26G-26H illustrate the structural coils of one embodiment of an implant delivery system.
  • an optional spring 1 16 is placed between the heater 106 and the implant device 1 12. The spring is compressed during assembly and the distal end of the tether 104 may be tied or coupled to the distal end of the implant device 1 12, or may be melted or otherwise formed into an atraumatic distal end 1 14.
  • the proximal region 356 may typically measure .005-.015 inches
  • the middle region 358 may typically measure .001 -.008 inches
  • the distal region 360 may typically measure .0005-.010 inches.
  • the core mandrel 354 will typically comprise between about 10-80% of the total diameter of the delivery pusher 350 at any point.
  • the delivery pusher 350 may include any number of different regions greater than or less than the three shown in Figure 7. Additionally, the radiopaque material of the core mandrel 354 may only extend partially through the delivery pusher 350. For example, the radiopaque material could extend from the proximal end of the core mandrel 354 to three centimeters from the distal end of the delivery pusher 350, providing yet another predetermined position marker visible under fluoroscopy. [00103] In this respect, the regions 356, 358, and 360 of delivery pusher 350 provide a more precise radiopaque marking system that is easily manufactured, yet is readily apparent under fluoroscopy. Further, the increased precision of the markers may decrease complications relating to improper positioning of the delivery pusher during a procedure.
  • FIG. 19-20 illustrate the distal-most portion of the pusher 700.
  • Current is supplied to a heater 704 by lead wire 706, which connects (e.g., via solder) to a distal end 704B of the heater 704, and a lead wire 708 that connects to a proximal end 704B of heater 704.
  • the wires 704, 706 are oppositely polarized to provide the current that flows through the heater to induce heat.
  • the coil 716 of the pusher 700 may utilize a stretch resistant wire 717 (Fig. 26F) to prevent the coil 716 of the pusher 700 from unduly stretching during movement within a patient.
  • this stretch resistant wire 717 is a 0.001 " diameter stainless steel wire which can be welded at a proximal portion of the assembly (within coil 716) at weld area 717A, about 5 cm from the distal tip of the implant delivery system. This location at 5 cm from the distal tip is also within coil 716.
  • the stretch resistant wire 717 may also be a polymer tether.
  • Hypotube 718 which contains both wires 706 and 708, may have a ground- down or thinned out proximal portion 721 (seen best in Figures 22, 24, and 25) to facilitate connection to the next section of the assembly, namely the tubular, outer polarized contact 726.
  • Figures 22-25 illustrate that the outer polarized contact 726 connects to lead wire 706, allowing an outside power supply to be connected to the pusher 700.
  • the contact 726 includes a distal slot 728, seen best in Figure 25, that at least partially aligns with a proximal slot 723 in the thinned out proximal portion 721 of the hypotube 718.
  • the outer tubular contact 726 is disposed over the distal, recessed end 721 of the mandrel 722, but is also spaced apart by an insulator sleeve 724, which prevents electrical contact between the contact 726 and the mandrel 722.
  • the insulator is a polyimide sleeve.
  • Mandrel 722 extends to the proximal end of the pusher 700, as shown in Figures 26A-C.
  • the mandrel 722 is further covered by a proximal tubular electrical contact 736, located proximally adjacent to contact 726, and by a hypotube 738, located proximally adjacent to contact 736 (Figs. 26A-26C).
  • the contact 736 is in physical, electrical contact with the mandrel 722 but insulated from other components on the pusher 700, thereby forming the second electrical connection point for a power supply to connect to. More specifically, the contact 736 is electrically isolated from contact 726 and hypotube 738 by insulators 740 and 742 (e.g., epoxy or insulating tubes).

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)
PCT/US2015/025594 2014-04-11 2015-04-13 Implant delivery system Ceased WO2015157768A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP22201761.8A EP4151164A1 (en) 2014-04-11 2015-04-13 Implant delivery system
CN201580030683.8A CN106659574B (zh) 2014-04-11 2015-04-13 植入物递送系统
EP15777509.9A EP3128961B1 (en) 2014-04-11 2015-04-13 Implant delivery system
JP2017504634A JP6749888B2 (ja) 2014-04-11 2015-04-13 インプラント配送システム

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461978686P 2014-04-11 2014-04-11
US61/978,686 2014-04-11

Publications (1)

Publication Number Publication Date
WO2015157768A1 true WO2015157768A1 (en) 2015-10-15

Family

ID=54264071

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2015/025594 Ceased WO2015157768A1 (en) 2014-04-11 2015-04-13 Implant delivery system

Country Status (5)

Country Link
US (4) US9867622B2 (enExample)
EP (2) EP3128961B1 (enExample)
JP (1) JP6749888B2 (enExample)
CN (1) CN106659574B (enExample)
WO (1) WO2015157768A1 (enExample)

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US11484319B2 (en) 2015-01-20 2022-11-01 Neurogami Medical, Inc. Delivery system for micrograft for treating intracranial aneurysms
CN107205736B (zh) 2015-01-20 2021-04-09 纽罗加米医药公司 用于颅内动脉瘤的治疗的微型移植物及使用方法
US10925611B2 (en) 2015-01-20 2021-02-23 Neurogami Medical, Inc. Packaging for surgical implant
US10857012B2 (en) 2015-01-20 2020-12-08 Neurogami Medical, Inc. Vascular implant
US10736730B2 (en) 2015-01-20 2020-08-11 Neurogami Medical, Inc. Vascular implant
CN113952095B (zh) 2015-09-18 2025-06-06 微仙美国有限公司 植入物固位、脱离以及递送系统
KR102747976B1 (ko) 2016-02-10 2025-01-02 마이크로벤션, 인코포레이티드 혈관 폐색을 위한 디바이스들
CN105662490B (zh) * 2016-03-08 2017-11-21 柳春雷 血管扩张器植入手术工具
WO2017201316A1 (en) 2016-05-18 2017-11-23 Microvention, Inc. Embolic containment
WO2017214577A1 (en) 2016-06-10 2017-12-14 Microvention, Inc. Vessel occluder
US10420563B2 (en) * 2016-07-08 2019-09-24 Neurogami Medical, Inc. Delivery system insertable through body lumen
CN110996805B (zh) 2017-05-25 2024-03-19 泰尔茂株式会社 粘合封堵系统
US11039840B2 (en) 2017-12-11 2021-06-22 Microvention, Inc. Implant detachment
DE102018109580A1 (de) * 2018-04-20 2019-10-24 Phenox Gmbh Vorrichtung zur Einbringung von Implantaten
US12114863B2 (en) * 2018-12-05 2024-10-15 Microvention, Inc. Implant delivery system
AU2020256222A1 (en) 2019-04-05 2021-11-04 Balt Usa, Llc Optimized detachment systems based on leverage from electrical locus targeting and related medical devices
BR112022002215A2 (pt) * 2019-08-06 2022-06-07 Microvention Inc Seringa
WO2022106903A1 (en) 2020-11-19 2022-05-27 Rapid Medical Ltd. Systems and methods for selective detachment of endovascular coils
JP2024510262A (ja) * 2021-03-19 2024-03-06 マイクロベンション インコーポレイテッド 複数の取り外し機構を備えるインプラント送達システム
EP4366629A4 (en) 2021-07-07 2025-04-23 Microvention, Inc. STRETCH-RESISTANT METAL COIL FOR EMBOLIZATION

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Also Published As

Publication number Publication date
US20180110528A1 (en) 2018-04-26
US20210204959A1 (en) 2021-07-08
EP4151164A1 (en) 2023-03-22
US12035918B2 (en) 2024-07-16
EP3128961B1 (en) 2022-11-02
CN106659574B (zh) 2018-12-25
EP3128961A4 (en) 2017-11-15
JP6749888B2 (ja) 2020-09-02
EP3128961A1 (en) 2017-02-15
CN106659574A (zh) 2017-05-10
JP2017517358A (ja) 2017-06-29
US20150289879A1 (en) 2015-10-15
US20250017587A1 (en) 2025-01-16
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