CN106659574B - 植入物递送系统 - Google Patents
植入物递送系统 Download PDFInfo
- Publication number
- CN106659574B CN106659574B CN201580030683.8A CN201580030683A CN106659574B CN 106659574 B CN106659574 B CN 106659574B CN 201580030683 A CN201580030683 A CN 201580030683A CN 106659574 B CN106659574 B CN 106659574B
- Authority
- CN
- China
- Prior art keywords
- propeller
- electrical contacts
- heater
- rope
- coil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12154—Coils or wires having stretch limiting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00026—Conductivity or impedance, e.g. of tissue
- A61B2017/0003—Conductivity or impedance, e.g. of tissue of parts of the instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00929—Material properties isolating electrical current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
- A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
- A61B2017/12068—Details concerning the detachment of the occluding device from the introduction device detachable by heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0807—Indication means
- A61B2090/0808—Indication means for indicating correct assembly of components, e.g. of the surgical apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461978686P | 2014-04-11 | 2014-04-11 | |
| US61/978,686 | 2014-04-11 | ||
| PCT/US2015/025594 WO2015157768A1 (en) | 2014-04-11 | 2015-04-13 | Implant delivery system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106659574A CN106659574A (zh) | 2017-05-10 |
| CN106659574B true CN106659574B (zh) | 2018-12-25 |
Family
ID=54264071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580030683.8A Active CN106659574B (zh) | 2014-04-11 | 2015-04-13 | 植入物递送系统 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US9867622B2 (enExample) |
| EP (2) | EP3128961B1 (enExample) |
| JP (1) | JP6749888B2 (enExample) |
| CN (1) | CN106659574B (enExample) |
| WO (1) | WO2015157768A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11484319B2 (en) | 2015-01-20 | 2022-11-01 | Neurogami Medical, Inc. | Delivery system for micrograft for treating intracranial aneurysms |
| CN107205736B (zh) | 2015-01-20 | 2021-04-09 | 纽罗加米医药公司 | 用于颅内动脉瘤的治疗的微型移植物及使用方法 |
| US10925611B2 (en) | 2015-01-20 | 2021-02-23 | Neurogami Medical, Inc. | Packaging for surgical implant |
| US10857012B2 (en) | 2015-01-20 | 2020-12-08 | Neurogami Medical, Inc. | Vascular implant |
| US10736730B2 (en) | 2015-01-20 | 2020-08-11 | Neurogami Medical, Inc. | Vascular implant |
| CN113952095B (zh) | 2015-09-18 | 2025-06-06 | 微仙美国有限公司 | 植入物固位、脱离以及递送系统 |
| KR102747976B1 (ko) | 2016-02-10 | 2025-01-02 | 마이크로벤션, 인코포레이티드 | 혈관 폐색을 위한 디바이스들 |
| CN105662490B (zh) * | 2016-03-08 | 2017-11-21 | 柳春雷 | 血管扩张器植入手术工具 |
| WO2017201316A1 (en) | 2016-05-18 | 2017-11-23 | Microvention, Inc. | Embolic containment |
| WO2017214577A1 (en) | 2016-06-10 | 2017-12-14 | Microvention, Inc. | Vessel occluder |
| US10420563B2 (en) * | 2016-07-08 | 2019-09-24 | Neurogami Medical, Inc. | Delivery system insertable through body lumen |
| CN110996805B (zh) | 2017-05-25 | 2024-03-19 | 泰尔茂株式会社 | 粘合封堵系统 |
| US11039840B2 (en) | 2017-12-11 | 2021-06-22 | Microvention, Inc. | Implant detachment |
| DE102018109580A1 (de) * | 2018-04-20 | 2019-10-24 | Phenox Gmbh | Vorrichtung zur Einbringung von Implantaten |
| US12114863B2 (en) * | 2018-12-05 | 2024-10-15 | Microvention, Inc. | Implant delivery system |
| AU2020256222A1 (en) | 2019-04-05 | 2021-11-04 | Balt Usa, Llc | Optimized detachment systems based on leverage from electrical locus targeting and related medical devices |
| BR112022002215A2 (pt) * | 2019-08-06 | 2022-06-07 | Microvention Inc | Seringa |
| WO2022106903A1 (en) | 2020-11-19 | 2022-05-27 | Rapid Medical Ltd. | Systems and methods for selective detachment of endovascular coils |
| JP2024510262A (ja) * | 2021-03-19 | 2024-03-06 | マイクロベンション インコーポレイテッド | 複数の取り外し機構を備えるインプラント送達システム |
| EP4366629A4 (en) | 2021-07-07 | 2025-04-23 | Microvention, Inc. | STRETCH-RESISTANT METAL COIL FOR EMBOLIZATION |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997001368A1 (en) * | 1995-06-26 | 1997-01-16 | Trimedyne, Inc. | Therapeutic appliance releasing device |
| US5873835A (en) * | 1993-04-29 | 1999-02-23 | Scimed Life Systems, Inc. | Intravascular pressure and flow sensor |
| CN101842061A (zh) * | 2007-06-25 | 2010-09-22 | 微排放器公司 | 自扩展假体 |
| CN103002837A (zh) * | 2010-04-30 | 2013-03-27 | 艾博特心血管系统公司 | 用于将支架安装至球囊导管的方法 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3324280A (en) | 1964-08-06 | 1967-06-06 | Frank E Cheney | Insulated metal sheath heating element for electric water heaters |
| US4346712A (en) | 1979-04-06 | 1982-08-31 | Kuraray Company, Ltd. | Releasable balloon catheter |
| JPS63294852A (ja) | 1987-05-28 | 1988-12-01 | Koji Yoshida | 胆管癌治療装置 |
| US4885217A (en) * | 1987-07-06 | 1989-12-05 | Alupower, Inc. | Air cathodes and materials therefor |
| US5976131A (en) | 1990-03-13 | 1999-11-02 | The Regents Of The University At California | Detachable endovascular occlusion device activated by alternating electric current |
| US5354295A (en) | 1990-03-13 | 1994-10-11 | Target Therapeutics, Inc. | In an endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| USRE41029E1 (en) | 1990-03-13 | 2009-12-01 | The Regents Of The University Of California | Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US5851206A (en) | 1990-03-13 | 1998-12-22 | The Regents Of The University Of California | Method and apparatus for endovascular thermal thrombosis and thermal cancer treatment |
| US5569245A (en) | 1990-03-13 | 1996-10-29 | The Regents Of The University Of California | Detachable endovascular occlusion device activated by alternating electric current |
| US5122136A (en) | 1990-03-13 | 1992-06-16 | The Regents Of The University Of California | Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US6083220A (en) | 1990-03-13 | 2000-07-04 | The Regents Of The University Of California | Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas |
| US5108407A (en) | 1990-06-08 | 1992-04-28 | Rush-Presbyterian St. Luke's Medical Center | Method and apparatus for placement of an embolic coil |
| US5217484A (en) | 1991-06-07 | 1993-06-08 | Marks Michael P | Retractable-wire catheter device and method |
| US5382259A (en) | 1992-10-26 | 1995-01-17 | Target Therapeutics, Inc. | Vasoocclusion coil with attached tubular woven or braided fibrous covering |
| US5470338A (en) | 1993-10-08 | 1995-11-28 | United States Surgical Corporation | Instrument for closing trocar puncture wounds |
| JP2880070B2 (ja) | 1994-03-31 | 1999-04-05 | 株式会社カネカメディックス | 生体内留置部材を有する医療用ワイヤー |
| US5814062A (en) | 1994-12-22 | 1998-09-29 | Target Therapeutics, Inc. | Implant delivery assembly with expandable coupling/decoupling mechanism |
| US5853418A (en) | 1995-06-30 | 1998-12-29 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils (II) |
| US5582619A (en) | 1995-06-30 | 1996-12-10 | Target Therapeutics, Inc. | Stretch resistant vaso-occlusive coils |
| JPH0966109A (ja) * | 1995-09-04 | 1997-03-11 | Olympus Optical Co Ltd | 医療用チューブ |
| JP3754145B2 (ja) | 1996-09-20 | 2006-03-08 | 株式会社カネカメディックス | 生体内留置部材を有する医療用ワイヤー |
| US5944733A (en) | 1997-07-14 | 1999-08-31 | Target Therapeutics, Inc. | Controlled detachable vasoocclusive member using mechanical junction and friction-enhancing member |
| US6159206A (en) | 1997-10-30 | 2000-12-12 | Kaneka Medix Corporation | Medical implement for depositing implanted device and method of depositing implanted device |
| US5941888A (en) | 1998-02-18 | 1999-08-24 | Target Therapeutics, Inc. | Vaso-occlusive member assembly with multiple detaching points |
| US6077260A (en) | 1998-02-19 | 2000-06-20 | Target Therapeutics, Inc. | Assembly containing an electrolytically severable joint for endovascular embolic devices |
| US6500149B2 (en) | 1998-08-31 | 2002-12-31 | Deepak Gandhi | Apparatus for deployment of micro-coil using a catheter |
| US6478773B1 (en) | 1998-12-21 | 2002-11-12 | Micrus Corporation | Apparatus for deployment of micro-coil using a catheter |
| US6277126B1 (en) | 1998-10-05 | 2001-08-21 | Cordis Neurovascular Inc. | Heated vascular occlusion coil development system |
| WO2000072781A2 (en) | 1999-06-02 | 2000-12-07 | Sethel Interventional, Inc. | Intracorporeal occlusive device |
| US6398802B1 (en) | 1999-06-21 | 2002-06-04 | Scimed Life Systems, Inc. | Low profile delivery system for stent and graft deployment |
| US6158206A (en) | 1999-08-17 | 2000-12-12 | D&W Jewelry, Inc. | Modified gap for jewelry rope chain link |
| KR100387384B1 (ko) | 2000-07-26 | 2003-06-12 | 규 호 이 | 색전 물질 분리 검출 시스템 및 그의 방법과 색전술용어셈블리 |
| US6605101B1 (en) | 2000-09-26 | 2003-08-12 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
| US6743251B1 (en) | 2000-11-15 | 2004-06-01 | Scimed Life Systems, Inc. | Implantable devices with polymeric detachment junction |
| US20020123755A1 (en) | 2001-03-01 | 2002-09-05 | Scimed Life Systems, Inc. | Embolic protection filter delivery sheath |
| US6602269B2 (en) | 2001-03-30 | 2003-08-05 | Scimed Life Systems | Embolic devices capable of in-situ reinforcement |
| US6716238B2 (en) | 2001-05-10 | 2004-04-06 | Scimed Life Systems, Inc. | Stent with detachable tethers and method of using same |
| CA2449137A1 (en) * | 2001-06-01 | 2002-12-05 | Jean Raymond | Detachable tip microcatheter for use of liquid embolic agents |
| US7048719B1 (en) | 2002-06-07 | 2006-05-23 | Microvention, Inc. | Endovascular catheter resheathing apparatus and related methods |
| US7485122B2 (en) | 2002-06-27 | 2009-02-03 | Boston Scientific Scimed, Inc. | Integrated anchor coil in stretch-resistant vaso-occlusive coils |
| CA2441396C (en) | 2002-07-19 | 2010-07-13 | Micrus Corporation | Apparatus for deployment of micro-coil using a catheter |
| US7608058B2 (en) | 2002-07-23 | 2009-10-27 | Micrus Corporation | Stretch resistant therapeutic device |
| US6807446B2 (en) | 2002-09-03 | 2004-10-19 | Celsion Corporation | Monopole phased array thermotherapy applicator for deep tumor therapy |
| ATE504241T1 (de) | 2003-01-10 | 2011-04-15 | Kaneka Corp | Embolus-bildendes in-vivo-verweilimplantat |
| JP2004261234A (ja) | 2003-02-20 | 2004-09-24 | Kaneka Medix Corp | 塞栓形成用体内留置具 |
| WO2005042081A1 (en) | 2003-10-28 | 2005-05-12 | Peacock James C Iii | Embolic filter device and related systems and methods |
| US20060241682A1 (en) | 2003-12-08 | 2006-10-26 | Kurz Daniel R | Intravascular device push wire delivery system |
| CN101415459B (zh) | 2004-08-25 | 2014-11-05 | 麦克罗文逊股份有限公司 | 可植入物装置的热脱离系统 |
| US8998926B2 (en) | 2006-04-06 | 2015-04-07 | DePuy Synthes Products, LLC | Heat detachable coil |
| US20080306503A1 (en) | 2006-11-20 | 2008-12-11 | Boston Scientific Scimed, Inc. | Mechanically detachable vaso-occlusive device |
| CN101835430B (zh) | 2007-03-13 | 2013-06-05 | 泰科保健集团有限合伙公司 | 包括线圈和抗拉伸构件的植入物 |
| ES2627125T3 (es) * | 2007-05-18 | 2017-07-26 | Stryker European Holdings I, Llc | Sistemas de separación de implantes médicos |
| WO2009012057A2 (en) * | 2007-07-13 | 2009-01-22 | Boston Scientific Scimed, Inc. | Hybrid and portable power supplies for electrolytically detaching implantable medical devices |
| WO2009014883A1 (en) * | 2007-07-20 | 2009-01-29 | Boston Scientific Scimed, Inc. | Power supply using time varying signal for electrolytically detaching implantable device |
| US20090270901A1 (en) | 2007-10-30 | 2009-10-29 | Boston Scientific Scimed, Inc. | Degradable detachment mechanisms for implantable devices |
| US20100160944A1 (en) * | 2008-12-24 | 2010-06-24 | Boston Scientific Scimed, Inc. | Thermally detachable embolic assemblies |
| US9095450B2 (en) * | 2008-12-24 | 2015-08-04 | DePuy Syntheses Products, Inc. | Insertion instrument for anteriorly inserting intervertebral spinal implants |
| WO2010104955A2 (en) * | 2009-03-13 | 2010-09-16 | Boston Scientific Scimed, Inc. | Electrical contact for occlusive device delivery system |
| BRPI1014975A2 (pt) * | 2009-04-15 | 2016-04-26 | Microventon Inc | sistema de entrega de implante |
| WO2010120694A1 (en) | 2009-04-16 | 2010-10-21 | Boston Scientific Scimed, Inc. | Electrical contact for occlusive device delivery system |
| WO2011053620A1 (en) * | 2009-11-02 | 2011-05-05 | Boston Scientific Scimed, Inc. | Occlusive device delivery system |
| BR112012025969B1 (pt) | 2010-04-14 | 2021-01-05 | Microvention, Inc. | dispositivo de fornecimento de implante |
| US20120116350A1 (en) | 2010-07-07 | 2012-05-10 | Reverse Medical Corporation | Translation dilator and stand alone vascular guide catheter |
| WO2013149683A1 (en) * | 2012-04-02 | 2013-10-10 | Flux Medical N.V. | Implant device and system for ablation of a vessel's wall from the inside |
| US8795313B2 (en) | 2011-09-29 | 2014-08-05 | Covidien Lp | Device detachment systems with indicators |
| US9155540B2 (en) | 2012-03-30 | 2015-10-13 | DePuy Synthes Products, Inc. | Embolic coil detachment mechanism with heating element and kicker |
| US8932318B2 (en) | 2012-03-30 | 2015-01-13 | DePuy Synthes Products, LLC | Embolic coil detachment mechanism with polymer tether |
| US20140058434A1 (en) | 2012-08-21 | 2014-02-27 | Donald K. Jones | Releasable device system |
| US8597323B1 (en) * | 2012-11-16 | 2013-12-03 | Sequent Medical, Inc. | Delivery and detachment systems and methods for vascular implants |
-
2015
- 2015-04-13 US US14/685,312 patent/US9867622B2/en active Active
- 2015-04-13 EP EP15777509.9A patent/EP3128961B1/en active Active
- 2015-04-13 CN CN201580030683.8A patent/CN106659574B/zh active Active
- 2015-04-13 JP JP2017504634A patent/JP6749888B2/ja active Active
- 2015-04-13 EP EP22201761.8A patent/EP4151164A1/en active Pending
- 2015-04-13 WO PCT/US2015/025594 patent/WO2015157768A1/en not_active Ceased
-
2017
- 2017-12-12 US US15/839,671 patent/US10980544B2/en active Active
-
2021
- 2021-03-16 US US17/203,564 patent/US12035918B2/en active Active
-
2024
- 2024-06-18 US US18/747,254 patent/US20250017587A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5873835A (en) * | 1993-04-29 | 1999-02-23 | Scimed Life Systems, Inc. | Intravascular pressure and flow sensor |
| WO1997001368A1 (en) * | 1995-06-26 | 1997-01-16 | Trimedyne, Inc. | Therapeutic appliance releasing device |
| CN101842061A (zh) * | 2007-06-25 | 2010-09-22 | 微排放器公司 | 自扩展假体 |
| CN103002837A (zh) * | 2010-04-30 | 2013-03-27 | 艾博特心血管系统公司 | 用于将支架安装至球囊导管的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20180110528A1 (en) | 2018-04-26 |
| US20210204959A1 (en) | 2021-07-08 |
| EP4151164A1 (en) | 2023-03-22 |
| US12035918B2 (en) | 2024-07-16 |
| EP3128961B1 (en) | 2022-11-02 |
| EP3128961A4 (en) | 2017-11-15 |
| JP6749888B2 (ja) | 2020-09-02 |
| EP3128961A1 (en) | 2017-02-15 |
| WO2015157768A1 (en) | 2015-10-15 |
| CN106659574A (zh) | 2017-05-10 |
| JP2017517358A (ja) | 2017-06-29 |
| US20150289879A1 (en) | 2015-10-15 |
| US20250017587A1 (en) | 2025-01-16 |
| US9867622B2 (en) | 2018-01-16 |
| US10980544B2 (en) | 2021-04-20 |
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