WO2015152514A1 - Dispositif de surveillance de patient et dispositif de surveillance de la fonction rénale - Google Patents

Dispositif de surveillance de patient et dispositif de surveillance de la fonction rénale Download PDF

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Publication number
WO2015152514A1
WO2015152514A1 PCT/KR2015/000954 KR2015000954W WO2015152514A1 WO 2015152514 A1 WO2015152514 A1 WO 2015152514A1 KR 2015000954 W KR2015000954 W KR 2015000954W WO 2015152514 A1 WO2015152514 A1 WO 2015152514A1
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WIPO (PCT)
Prior art keywords
information
body fluid
time
event
discharge
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PCT/KR2015/000954
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English (en)
Korean (ko)
Inventor
김정회
김승태
Original Assignee
(주)엠큐브테크놀로지
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Publication of WO2015152514A1 publication Critical patent/WO2015152514A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201—Assessing renal or kidney functions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/207—Sensing devices adapted to collect urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery

Definitions

  • the present invention relates to a patient monitoring device and kidney function monitoring device, and more particularly, to the function of the kidney or the function of the patient through an accurate real-time measurement of the fluid discharge collected in the fluid collection bag such as a urine bag mounted on the patient, etc.
  • a patient monitoring device and kidney function monitoring device for monitoring the condition are provided.
  • the kidney is an organ that produces urine by filtering the blood supplied to the kidney and discharges it into the bladder. By monitoring the function of the kidney, the kidney can check whether the blood is circulating. In particular, in the event of surgery, general anesthesia, or kidney transplantation, which greatly affect the amount of blood supplied to each organ of the patient's body, to determine whether circulating blood volume is normal, whether kidney function is restored or not. Continuous monitoring
  • a urinary catheter is inserted into the patient's bladder or kidney and a urine bag is connected to one end of the catheter to collect urine generated in the kidney into the urine bag.
  • U.S. Patent No. 6,640,649 relates to "DROPLET COUNTER FOR LOW FLOW RATES" and discloses an apparatus for measuring fluid flow.
  • the droplet counter disclosed in this patent measures a fluid flow using a laser sensor, and characterized in that the fluid is dropped in the form of droplets and the number of droplets is counted by a laser signal to calculate the amount of fluid flowing.
  • a droplet counter using the method according to this patent requires a specially constructed component consisting of a first chamber (12) and a second chamber (17) for producing and counting water droplets, which are in series on a bodily fluid discharge tube. It is a consumable that must be connected and must be sterilized to prevent infection of the patient and to be discarded after one use. Therefore, the method according to this patent is practically used.
  • the object according to the invention for solving the above-mentioned problems is to It is to provide a patient monitoring device that can determine the state of the patient by measuring the discharge of the discharged or discharged body fluid, and analyzing and monitoring it in real time.
  • Another object of the present invention is to measure the amount of fluid discharged or released from a patient, analyze event information and / or drug injection information provided from an infusion controller, and compare event information and / or drug injection information with fluid discharge.
  • the present invention provides a patient monitoring device that can monitor correlations of patients in real time by outputting correlations in real time through time series graphs.
  • Another object according to the present invention is to provide a kidney monitoring device that allows a patient to measure the condition of the urine bag and analyze the measurement data to monitor the condition or function of the kidney in real time.
  • Another object of the present invention is to provide a kidney monitoring method that can monitor the state or function of the kidney in real time using the urine discharge information collected in real time in the kidney monitoring device described above.
  • Another object of the present invention is to collect the drug injection information about the drug or the sap injected into the patient, to detect the urine discharge from the measurement data measuring the state of the urine bag, to analyze the urine discharge and event information and drug injection information In addition, by analyzing the urine output and event information and drug injection information per unit time, it is to provide a kidney function monitoring device that can monitor in real time whether the recovery of the kidney status and function according to the event or drug injection.
  • a first aspect of the present invention for achieving the above-described technical problem relates to a patient monitoring device by measuring the body fluid discharge, body fluid collector for collecting and storing the body fluid generated and discharged from the human body of the patient;
  • a bodily fluid collector state meter which measures a state of the bodily fluid collector at a preset sampling time and provides measurement data in real time; And generating body fluid discharge information using measurement data provided from the body fluid collector state meter, generating event information using an event signal input from the outside, and
  • a main body configured to analyze body fluid discharge information and event information, the main body comprising: a signal input unit configured to receive measurement data from a body fluid collector state measuring device in real time; An event input unit configured to receive an event signal from the outside; A data output unit; Receiving measurement data from the signal input unit in real time, generating bodily fluid discharge information using the measured data, generating event information using the event signal provided from the event input unit, and receiving the bodily fluid discharge information and the event information.
  • a control unit for analyzing and outputting
  • the body fluid discharge information includes body fluid discharge and detection time information of detecting the body fluid discharge
  • the event information includes an event item and an event occurrence time
  • Analyze the body fluid discharge information and event information it is preferable to output the analysis results in a time series graph.
  • control unit is operated in one of a plurality of operation modes by using body fluid discharge information and event information
  • the controller If the first operation mode is selected, the controller outputs the body fluid discharge and event information for each detection time to the data output unit. If the second operation mode is selected, the controller extracts the discharge per unit time from the fluid discharge for each detection time. It is preferable to output the discharge per unit time and event information for each detection time to a data output unit.
  • An apparatus for monitoring a patient comprising: an infusion controller configured to provide, in real time, information related to an infusion related to an infusion to a patient in real time;
  • the injection related information further includes an injection amount per unit time and a total injection amount.
  • the control unit generates drug injection information using the injection related information provided from the injection controller, and the drug injection information is a unit. It is characterized in that it comprises the injection amount information or total injection amount information, and the injection time information, wherein the control unit preferably analyzes the body fluid discharge information and drug injection information and provide an analysis result,
  • the controller may be operated in one of a plurality of operation modes by using bodily fluid discharge information, event information, and drug injection information.
  • the controller may, in response to the first operation mode being selected, bodily fluid discharge and event information for each detection time.
  • Output to the data output unit if the second operation mode is selected, extract the discharge per unit time from the body fluid discharge information, output the discharge per unit time and event information for each detection time to the data output unit, the third operation mode If is selected, the fluid discharge amount, total injection amount and event information for each detection time is output to the data output unit, if the fourth operation mode is selected, the discharge per unit time is extracted from the body fluid discharge information, the discharge per unit time, the total injection amount and Outputting event information to a data output unit; When the operation mode is selected, the bodily fluid discharge amount, the injection amount per unit time and event information for each detection time are output to the data output unit. When the sixth operation mode is selected, the discharge per unit time is extracted from the bodily fluid discharge information. It is more preferable to output the output per unit time, injection amount per unit time and event information to the data output unit.
  • the body fluid collector state measuring device a cradle for mounting the body fluid collector; And a weight sensor for measuring the weight of the body fluid collector mounted on the holder, and providing measurement data for the body fluid collector measured by the weight sensor to the main body.
  • a kidney function monitoring apparatus comprising: a urine bag state measuring device measuring a state of a urine bag at a predetermined sampling time and providing measurement data in real time; And generating urine excretion information using measurement data provided from the urine bag state measuring device, generating event information using an event signal input from the outside, analyzing urine excretion information and event information, and using kidney analysis results.
  • a main body for monitoring a function ;
  • the main body the signal input unit for receiving the measurement data in real time from the urine bag state measuring device; An event input unit configured to receive an event signal from the outside; A data output unit; Measurement data from the signal input unit. It is provided in real time, the urine discharge information is generated using the measured data, the event information is generated using the event signal provided from the event input unit, the event information and urine discharge information is analyzed and the analyzed results are outputted to the data. And a control unit output to the unit.
  • the urine discharge information includes urine discharge and detection time information of detecting the urine discharge
  • the event information includes an event item and an event occurrence time.
  • the control unit analyzes urine discharge information and event information according to each detection time, and outputs the analyzed results as a time series graph.
  • the control unit may be operated in one of a plurality of operation modes using urine discharge information and event information.
  • the control unit may output urine discharge and event information for each detection time when the first operation mode is selected. It is more preferable to output to the data outputting section the output per unit time and the event information for each detection time when the second operation mode is selected.
  • An apparatus for monitoring kidney function comprising: an infusion controller configured to provide, in real time, an injection tube 3 ⁇ 4 information to be injected into a patient for a predetermined time; Further comprising, the injection related information is characterized in that it comprises an injection amount per unit time or total injection amount,
  • the controller generates drug injection information using the injection related information provided from the injection controller, wherein the drug injection information includes the injection amount information or total injection amount information per unit time, and injection time information. It is preferable to analyze the urine discharge information or unit time discharge information and the drug injection information according to the detection time, and the controller is operated in one of a plurality of operation modes using the urine discharge information, drug injection information and event information.
  • the control unit outputs the urine discharge and event information for each detection time to the data output unit when the first operation mode is selected, and the discharge and event per unit time for each detection time when the second operation mode is selected. Information is output to the data output unit.
  • Urine for each detection time if selected When the discharge, total injection amount, and event information is output to the data output unit, and when the operation mode is selected, the output per unit time, total injection amount and event information for each detection time is output to the data output unit. If selected, the urine discharge, injection amount per unit time, and event information for each detection time are output to the data output unit. If the sixth operation mode is selected, output per unit time discharge, injection amount and event information for each detection time is output. It is more preferable to output to a negative part.
  • the urine bag condition measuring device a cradle for mounting the urine bag; And a weight sensor for sensing the weight of the urine bag mounted on the holder. It is preferable to provide the measurement data for the urine bag measured by the weight sensor to the main body.
  • a bodily fluid collector state measuring device for measuring the weight of a bodily fluid collector includes: a weight sensing sensor fixedly mounted to one surface of a housing and outputting a sensing signal according to a weight; Mounting the body fluid collector, the cradle to move in the direction of gravity by the load of the body fluid collector; And an elastic member disposed between the weight sensor and the cradle to transmit the load of the cradle to the weight sensor, wherein the load of the cradle is transmitted to the weight sensor through the elastic member, Output the detection signal to the outside.
  • the weight sensor is preferably configured of a load cel using a strain gage.
  • a bodily fluid collector state measuring device for measuring the weight of a bodily fluid collector further comprising: a sensor protection member fixedly mounted to one surface of the housing and configured such that the movable range of the cradle is not within a preset range; Preferably, the preset range is determined by the rated capacity of the weight sensor.
  • the body fluid collector is characterized in that it is a urine bag.
  • the patient monitoring apparatus analyzes the body fluid discharge information and event information and / or drug injection information over time, and outputs the analyzed results in real time together, according to the occurrence of the event or injection of drugs, etc. Changes in bodily fluids can be identified in real time, and the extent to which the occurrence of events or infusions of drugs affect the variability of fluids in each patient.
  • the renal function monitoring apparatus is applied to the above-described patient monitoring device for renal function monitoring, by measuring the weight of the urine bag connected to the catheter inserted into the patient * real time to detect the urine discharge of the patient in real time
  • urine excretion information including the analysis of urine excretion information, event information and / or drug infusion information
  • outputs the analysis results provided urine according to the occurrence of events such as surgery and / or injection of drugs
  • urine is also possible to determine how much an event or drug infusion affects the change in urine output in each patient, thereby monitoring kidney function.
  • the patient monitoring device and kidney function monitoring device is a fluid collector state measuring instrument or urine measuring and providing in real time the weight of the body fluid collector or urine bag.
  • a bag condition meter By providing a bag condition meter, the weight of the fluid collector or urine bag can be measured more accurately and simply.
  • the above-mentioned body fluid collector state measuring device uses a load cell, and further includes an elastic member and a sensor protecting member to protect the load cell, so that even if a sudden increase in load, an external lamella, or an overload exceeding the rated load is applied, The cell can be prevented from being broken.
  • FIG. 1 is a block diagram schematically showing a patient monitoring apparatus according to a first preferred embodiment of the present invention.
  • Figure 2 is a patient monitoring device according to the second embodiment of the present invention It is a schematic block diagram.
  • FIG. 3 is a graph illustrating an example of a screen output to a data output unit when three controllers are driven in a third operation mode in a patient monitoring apparatus and a kidney function monitoring apparatus according to the first and third exemplary embodiments of the present invention; to be.
  • FIG. 4 is a graph illustrating an example of a screen output to a data output unit when a control unit is driven in a crab 4 operation mode in the patient monitoring device and the kidney function monitoring device according to the first and third embodiments of the present invention; to be.
  • FIG. 5 is a graph illustrating an example of a screen output to a data output unit when a control unit is driven in a seventh operation mode in a patient monitoring apparatus and a kidney function monitoring apparatus according to the second and fourth embodiments of the present invention. to be.
  • FIG. 6 is a graph illustrating an example of a screen output to a data output unit when the control unit is driven in the eighth operation mode in the patient monitoring device and the kidney function monitoring device according to the second and fourth embodiments of the present invention. to be.
  • FIG. 7 is a schematic view showing a body fluid collector state measuring device according to a sixth embodiment of the present invention.
  • the patient monitoring device measures the state of a bodily fluid collector connected to a catheter inserted or mounted in a patient and analyzes the measured data to generate bodily fluid discharge information in real time, and the fluid discharge information ⁇ event information and / Alternatively, by analyzing the drug injection information together and providing the analysis result, it is possible to monitor in real time the fluid discharge and / or f low rate according to the occurrence of the event or drug injection.
  • the body fluid discharge information includes at least body fluid discharge and detection time information of detecting the body fluid discharge.
  • the event information may be information indicating a change in the patient's condition, such as surgery or procedure, bowel movement, weather, bedtime, drink intake, or diuretics.
  • the drug injection information refers to information that the liquid such as drugs or fluids are injected into the human body, such as a patient through the external infusion regulator for a certain time, and one of the total injection amount or injection per unit time of the liquid such as drugs or fluids At least injection time information.
  • the patient monitoring device by measuring the urine discharge collected in the urine bag in real time in order to monitor the kidney function of the patient, the change of urine discharge according to the injection of the event or the drug by the infusion regulator and thus It is characterized in that to monitor the kidney function in real time.
  • FIG. 1 is a block diagram schematically showing a patient monitoring apparatus according to a first preferred embodiment of the present invention.
  • the patient monitoring apparatus 2 includes a main body 200 and a body fluid collector state meter 250 connected to the main body.
  • the body fluid refers to those produced and discharged from specific organs of the human body, such as blood, lymph, urine, sweat, saliva, and tears.
  • the body fluid collector state detector 250 measures the state of the body fluid collector, for example, weight, volume, pressure, and length, in real time, and provides measurement data to the main body in real time.
  • the bodily fluid collector is connected to a catheter inserted into an organ through which specific bodily fluid is discharged from the patient's body, and collects bodily fluid discharged to a specific organ of the human body through the catheter.
  • An example of a bodily fluid collector is a urine bag, and can be used in various ways. Therefore, since the state of the bodily fluid collector changes according to the total amount of the bodily fluid discharged to the bodily fluid collector, the state of the bodily fluid collector can be measured in real time by the magnetic flux, so that the bodily fluid discharge of the patient can be detected from the measured data in real time.
  • the fluid discharge detected in real time is the total discharge Qv collected in the fluid collector from the start time of the measurement to the measurement time.
  • the bodily fluid collector state measurer 250 measures and provides state information such as weight, weight, pressure, and length of the bodily fluid collector, and detects a state of the cradle 252 for mounting the bodily fluid collector and the bodily fluid collector mounted to the cradle. It provides a measurement sensor 254 to provide.
  • the measuring sensor may use a weight sensor for measuring the weight of the bodily fluid collector, and the weight sensor may be a load sal using a strain gage as an example. load cel l).
  • the bodily fluid collector state meter 250 may be variously configured with a cradle and a measuring sensor according to the type of state information to be measured. Accordingly, the present invention is not limited to the configuration of the bodily fluid collector state meter, but can be easily derived by those skilled in the art, and can measure conditions such as mass or volume, pressure, and the like of the bodily fluid collector. All configurations will be included herein.
  • the bodily fluid collector state meter may further include a signal output unit.
  • the signal output unit comprises an amplifier for amplifying the minute detection signal provided from the measurement sensor and an A / D converter for converting the amplified signal into a digital signal.
  • the provided minute sensing signal may be amplified and then converted into a digital signal and output.
  • the main body 200 includes a signal input unit 210, a control unit 220, an event input unit 230, a data output unit 240, a display unit 241, a printer 242, an alarm output unit 250 and a communication '.
  • the interface unit 260 is provided.
  • the signal input unit 210 provides the detection signal received from the bodily fluid collector state meter to the controller 220.
  • the event input unit 230 provides an event item, etc. input from a user to the controller 200.
  • the event input unit 230 may include a keypad for inputting event-related information or a touch screen for key input.
  • the event is information indicating a change in the patient's condition, such as surgery or procedure, bowel movement, weather, bedtime, drink intake, or one-time injection of a specific drug such as a diuretic. It refers to an event that occurs once, for example.
  • the event information includes at least an event item.
  • the event item may be extracted from an event signal input from a user through an event input unit, and when it is possible to determine that an event has occurred from the event signal, the event item may be expressed as "Nul l" without additional information.
  • the event information may further include event occurrence time information, wherein the event occurrence time information is input from the user together with an event signal through an event input unit or when the event occurrence time information is not input through the event input unit.
  • the controller it is preferable that the controller sets the time when the event signal is input through the event input unit as event occurrence time information, and stores the same in the event information.
  • the data output unit 240 includes at least one of the display unit 241 and the printer 242.
  • the display unit 241 may be configured as a display panel such as a CRT, LCD, PDP, etc., and outputs information provided from the controller on a screen.
  • the printer 242 outputs information provided from the control unit to a graph paper or the like.
  • the data output unit may include only one of the display unit and the printer, or both of them.
  • the data output unit may be further provided if it can output data.
  • the alarm output unit 250 is driven according to an alarm signal provided from the control unit, and may include one or more buzzers for outputting an emergency sound, an LED or a lamp warning light that can repeatedly blink in an emergency. Can be.
  • the communication interface unit 260 is connected to a communication network such as the Internet or an intranet to transmit and receive data to an external central server or an adjacent external computer or terminal. Therefore, through the communication interface, the control unit may transmit data to a central server or the like or receive data from the central server or the like.
  • a communication network such as the Internet or an intranet to transmit and receive data to an external central server or an adjacent external computer or terminal. Therefore, through the communication interface, the control unit may transmit data to a central server or the like or receive data from the central server or the like.
  • the monitoring apparatus may further include a mode selector (not shown), and the mode selector may be configured by a plurality of different buttons or repeatedly press a single button. It allows the user to select one of a plurality of operating modes, to select a pause function, or to select a replacement function for replacing a fluid collector.
  • the mode selector provides information about the operation mode selected by the user to the controller.
  • the controller 220 includes a plurality of operation modes, generates body fluid discharge information using measurement data provided from the signal input unit, and generates event information using an event signal provided from the event input unit.
  • the control unit may be driven according to an operation mode that is preset or selected by the mode selection unit by using the body fluid discharge information and the event information, to allow the user to monitor the patient's condition in real time.
  • the control unit analyzes the fluid discharge information and the event information according to the operation mode selected or preset by the mode selection unit, and outputs the analysis result on the screen of the display unit and simultaneously prints them in the form of a graph by a printer, and outputs an alarm. Will print to the negative.
  • the bodily fluid discharge amount Qv is a value accumulated from the time point at which the measurement is started, and the bodily fluid discharge amount Qv (tl) at the arbitrary time point U is the random time tl from the measurement start time point tO.
  • the controller extracts the body fluid discharge from the measurement data, generates, stores, and manages the body fluid discharge information including the detection time information of detecting the corresponding body fluid discharge and the body fluid discharge.
  • the body fluid discharge information includes at least body fluid discharge and detection time information on which the body fluid discharge is detected.
  • the controller when an event signal is provided from an event input unit, the controller generates event information including at least an event item and event occurrence time information, and stores and manages the event information in a database.
  • the controller generates both event item and event occurrence time information from the event input unit, or sets event time provided by the event item as event occurrence time information when the event occurrence time information is not provided from the event input unit.
  • the control unit uses the measurement data provided from the signal input unit
  • the process of generating body fluid discharge information will be described in detail.
  • the body fluid discharge rate (Qv) is calculated using this, and the body fluid discharge information is configured with the measurement time and stored in the database.
  • the difference between the measured data of the previous time (t-1) and the measured time of the current time (t) is out of the preset error range, such as a rapid change in the fluid discharge due to external strata or other errors.
  • the noise of the measurement data may be attenuated by determining that the noise is corrected or by calculating an average value of the plurality of input measurement data every predetermined unit time.
  • various methods for correcting measurement data determined as noise have been proposed in the art, and one of such methods may be appropriately selected and used in the present invention.
  • the corrected measurement data is converted into bodily fluid discharge using a preset equation column, and bodily fluid discharge information including the bodily fluid discharge and detection time information of detecting the bodily fluid discharge is generated and stored and managed in a database.
  • the control unit pauses all jobs. Therefore, in a situation where it is difficult to measure the state of the bodily fluid collector, such as when the patient is moving, it is preferable to select the pause function so that the measurement is not performed.
  • the amount of fluid discharged before the replacement of the fluid collector is set as the reference amount, and when the replacement complete button is input or the replacement button is re-entered and the replacement completion information is input, the newly collected fluid discharge amount and the reference amount are set. In total, the amount of fluid discharged is set again. Therefore, when replacing a bodily fluid collector with a new bodily fluid collector, it is desirable that the bodily fluid discharge can be provided as the sum of the sum of the discharge collected from the old bodily fluid collector and the discharge collected from the new bodily fluid collector. By this summing process, even if the bodily fluid collector is newly replaced, the bodily fluid discharged from the replaced bodily fluid collector can be provided in sum with the bodily fluid discharged from the previous bodily fluid collector.
  • the controller includes an initialization mode and first to fourth operating modes.
  • the controller drives an initialization mode when a reset button is input or a start button is input. Otherwise, the controller drives the operation mode according to a button for selecting an operation mode.
  • the controller waits for an operation until the pause function is released.
  • the controller In the initialization mode, the controller initializes the measurement sensor of the bodily fluid collector state meter in the state where the bodily fluid collector is initially disposed, and sets the measurement sensor of the bodily fluid collector state meter as a zero point reference.
  • the controller In the first operation mode, the controller outputs the body fluid discharge Qv along with the detection time information t on the screen of the display unit in real time and simultaneously prints it to the printer.
  • the fluid discharge amount and the detection time information may be displayed in numbers, texts, and / or graphs. In particular, when the fluid discharge rate is displayed as a time series graph as shown in FIGS. Will be easier to see visually.
  • the control unit presets a range of a first reference value, that is, an upper limit value and / or a lower limit value, with respect to the body fluid discharge, and the range of the first reference value as shown in FIG. 4 or 6.
  • the controller may generate an alarm signal and provide the generated alarm signal to the alarm output unit when the bodily fluid discharged out of a range of a preset first reference value, such as the first warning section and the second warning section shown in FIG. 4 or 6. , Inform the caregiver or the caregiver by the operation of the alarm output unit.
  • a preset first reference value such as the first warning section and the second warning section shown in FIG. 4 or 6.
  • the control unit extracts the discharge per unit time (dQv / dt; f lowrate) from the body fluid discharge (Qv), and detects the discharge per unit time (dQv / dt) in real time with the detection time information (t). Output to the data output section.
  • the emission per unit time and the detection time information may be displayed in numbers, texts and / or graphs, and in particular, when displaying in time series graphs, the emission per unit time over time will be visually easier to understand. In this way, it is possible to easily grasp the fluid discharge and increase and decrease in real time through the unit hourly discharge displayed in the time series graph.
  • the control unit is configured to discharge the unit time per unit time.
  • the range of the second reference value may be preset and provided, and the range of the second reference value may be displayed together with the numbers, text, and / or graphs.
  • the controller generates an alarm signal to provide an alarm output unit when the discharge per unit time is out of the range of the second preset reference value, thereby informing the caregiver or caregiver of the alarm state by the operation of the alarm output unit.
  • the controller analyzes the body fluid discharge information and the event information, and outputs the analyzed result on the screen of the data output unit in real time.
  • the event information may include at least an event item and event occurrence time information, and the event item may be input through an event input unit, and the event occurrence time information may be input through an event input unit or may not be input through an event input unit.
  • the event input time may be set as event occurrence time information.
  • the event item may be displayed as "Nul l" when it includes information on the type of event or when there is no information on a separate event item and only indicates that an event has occurred.
  • the fluid discharge amount (Qv) according to each detection time and the event item according to the event occurrence time can be displayed in the same number, text and / or graph, especially when the time series graph is displayed in the graph And by displaying the event information together, it will be easier to grasp the change in body fluid discharge according to the event.
  • the user By displaying the corresponding event items in the time domain that is reflected in the event occurrence time information included in the event information on the time series graph indicating the fluid discharge, the user can visually easily identify the correlation between the event and the fluid discharge. .
  • the controller extracts the discharge per unit time (dQv / dt) from the body fluid discharge (Qv), analyzes the discharge per unit time (dQv / dt) and event information, and displays the analysis result in real time. Print to a copy and / or a printer.
  • the discharge per unit time, detection time information and event information can be displayed in a number, text and / or graph, in particular, when the time series graph is displayed in the graph the discharge per unit time event By displaying it with information, it will be easier to visually identify emissions per unit time and their correlations with events.
  • a patient monitoring apparatus uses body fluid discharge information, event information, and drug injection information about a drug or an fluid injected into a patient's human body by an infusion controller, and according to the injection of a drug or an fluid, etc.
  • an infusion controller uses body fluid discharge information, event information, and drug injection information about a drug or an fluid injected into a patient's human body by an infusion controller, and according to the injection of a drug or an fluid, etc.
  • FIG. 2 is a schematic diagram illustrating a patient monitoring apparatus according to a second embodiment of the present invention.
  • the patient monitoring apparatus 5 includes a body 500, a body fluid collector state meter 550, and an infusion controller 570 connected to the body.
  • the bodily fluid collector state meter 550 is the same as that of the first embodiment, and thus redundant description is omitted.
  • the infusion controller 570 is a device for injecting a liquid such as a drug or a fluid into the blood vessel of the patient, it characterized in that to provide infusion-related information injected into the patient to the main body 500 in real time.
  • the infusion-related information refers to information in which a liquid such as a drug or an infusion solut ion is injected into a patient for a predetermined time, and includes at least total injection amount information Qi or injection amount information dQi / dt per unit time.
  • the total injection amount information Qi means a total injection amount from an injection start time to a measurement time.
  • the infusion solut ion is an amino acid solution, glucose solution, fructose solution, or plasma for nutrient supply to supply essential ' nutrients such as physiological saline, ringer, or carbohydrate or protein for supplying water and electrolyte. Say the net.
  • the controller of the main body generates, stores, and manages drug infusion information using infusion-related information provided from an infusion controller.
  • the information refers to information in which a liquid such as drug or fluid is injected into a patient for a predetermined time, and includes at least a total injection amount Qi or an injection amount per unit time dQi / dt included in the injection related information.
  • the drug injection information may further include injection item information such as a drug to be injected, and the injection item information may be provided from an injection controller or directly input by a user through a main body.
  • the drug injection information may further include injection time information, and the injection time information may be provided as an injection time information provided by the injection controller or the control unit may set the time when the total injection amount or the injection amount per unit time is input from the injection controller. have.
  • the main body 500 includes a signal input unit 510, a control unit 520, an event input unit 530, a data output unit 540, a display unit 541, a printer 542, an alarm output unit 550, and a communication interface.
  • a unit 560 and an operation mode selection unit 570 are provided.
  • the signal input unit 510 receives the measurement data from the bodily fluid collector state meter and provides the control data to the controller 520, and receives the injection related information from the infusion controller in real time to the controller 520.
  • the event input unit 530, the data output unit 540, the display unit 541, the printer 542, the alarm output unit 550, the communication interface unit 560, and the operation mode selection unit 570 are the first embodiment. Since they are the same as those, duplicate descriptions are omitted.
  • the controller 520 generates the bodily fluid discharge information using the measurement data, generates the drug injection information using the injection related information provided from the infusion controller, and generates the event information using the event signal provided from the event input unit. It stores and manages in, and operates in one operation mode selected by the operation mode selection unit of a plurality of operation modes preset by using the body fluid discharge information, drug injection information and event information.
  • the controller includes an initialization mode and a first through eighth operation modes.
  • the initialization mode and the first to fourth operating modes are different from those of the first embodiment. Since it is the same, a description thereof will be omitted and the fifth to eighth operation modes will be described.
  • the controller extracts the total injection amount Qi from the drug injection information, and outputs the body fluid discharge amount Qv and the total injection amount information Qi in real time together with the detection time information t. Output to.
  • the fluid discharge amount and the total injection amount Qi according to each detection time information may be displayed in a similar number, a text and / or a graph, and in the case of displaying the time series graph, by outputting the fluid discharge amount and the total injection amount over time, It will be easier to visually identify changes in body fluid output following infusion information.
  • the controller may preset the range of the first reference value with respect to the body fluid discharge, and display the range of the first reference value in numbers, text, and / or graphs together.
  • the controller generates an alarm signal and provides an alarm signal to the caregiver or the caregiver by operating the alarm output unit when the bodily fluid discharge is out of the range of the first reference value.
  • the controller extracts the injection amount per unit time (dQi / dt) from the drug injection information or the total injection amount, and replaces the injection amount per unit time (dQi / dt) instead of the total injection amount (Qi) on a time series graph Can be provided along with fluid emissions.
  • the controller extracts the discharge per unit time (dQv / dt) from the body fluid discharge information, and detects the discharge per unit time (dQv / dt) and the total injection amount Qi in real time together with the detection time information (t). To the data output section. At this time, the discharge per unit time (dQv / dt), the total injection amount (Qi) and the detection time information can be displayed in a number, text and / or graph, in particular in the case of time series graphs discharged per unit time and total over time It will be easier to visually recognize the change in the discharge amount per unit time (dQv / dt) according to the injection amount QO.
  • the controller controls the range of the second provisional value with respect to the discharge amount per unit time. And presetting the second reference value to a number, text, and / or a graph; the controller may generate an alarm signal when the bodily fluid discharge is out of the preset second reference value.
  • To alarm output By providing an alarm state to the caregiver or the caregiver by the operation of the alarm output unit.
  • the controller extracts the injection amount per unit time (dQi / dt) from the drug injection information or the total injection amount, and replaces the injection amount per unit time (dQi / dt) instead of the total injection amount Qi on the time series graph. Can be provided along with the emission per unit time (dQv / dt).
  • the controller analyzes the body fluid discharge information, the drug injection information, and the event information, and outputs the analysis result on the screen of the data output unit in real time.
  • Fluid discharge over time (Qv), total infusion information (Qi) and event information (Event A, Event B, Event C) can be displayed numerically, textually and / or graphically.
  • the time series graph is displayed, the fluid discharge amount is displayed on the graph together with the event information and the total injection amount, so that the change of the fluid discharge according to the event and the drug injection will be more easily understood.
  • the device not only the body fluid discharge on a single time series graph, but also the drug injection information in the time domain of the injection time and the event information in the time domain of the event occurrence time are combined.
  • the user can visually easily grasp the correlation between the event information and the fluid discharge and the correlation between the drug injection information and the fluid discharge.
  • the control unit extracts the injection amount per unit time (dQi / dt) from the drug injection information or the total injection amount, and replaces the injection amount per unit time (dQi / dt) instead of the injection amount (Qi) on the time series graph It can be provided along with fluid discharge and event information.
  • the controller extracts the discharge per unit time (dQv / dt) from the body fluid discharge information, analyzes the discharge per unit time (dQv / dt), drug injection information and event information, and analyzes the analyzed result. Output to the data output section in real time.
  • the discharge per unit time (dQv / dt), the total injection amount (Qi) and the event information extracted from the drug injection information according to each detection time can be displayed in a flat, text and / or graph, especially in a time series graph In the above graph, the emission per unit time (dQv / dt), the event information and the total injection amount (Qi) are displayed together. It will be easier to see the amount of fluid changes following the injection.
  • the controller extracts the injection amount per unit time (dQi / dt) from the drug injection information or the total injection amount, and instead of the injection amount (Qi) on the time series graph unit
  • the hourly dose (dQi / dt) can be provided along with the hourly rate (dQv / dt) and event information.
  • the third and fourth embodiments according to the present invention apply the above-described patient monitoring devices of the first and second embodiments to a device for monitoring kidney function of a patient.
  • the third and fourth embodiments according to the present invention measure the state of the ur ine bag connected to the patient and analyze the measurement data to generate urine discharge information in real time. By providing it is possible to monitor in real time the recovery of the kidney state and kidney function of the patient.
  • the kidney monitoring apparatus according to the third embodiment includes a main body and a urine bag condition measuring device connected to the main body
  • the kidney monitoring device according to the fourth embodiment includes a main body and a urine bag condition measuring device connected to the main body and an infusion controller. It is done.
  • the main body, urine bag condition meter, and infusion regulator of the kidney function monitoring apparatus according to the third and fourth embodiments are respectively applied to the main body, the body fluid collector state meter, and the infusion regulator of the first and second embodiments, and the basic configuration thereof is different from each other. same.
  • the urine bag state measuring device measures the state of the urine bag (ur ine bag), for example, weight, volume, pressure, length, etc. in real time, and provides the measurement data to the main body in real time.
  • a ur ine bag is connected to a catheter inserted into the bladder or kidney of the patient, and urine discharged from the patient's kidney into the bladder is immediately collected into the urine bag through the catheter.
  • the state of the urine bag changes according to the amount of urine collected in the urine bag, the state of the urine bag is continuously measured in real time.
  • the patient's urine output can be extracted from the data in real time.
  • the main body includes a signal input unit, a control unit, an event input unit, a data output unit, a display unit, a printer, an alarm output unit, and a communication interface unit, and these components are the same as those of the first and second embodiments described above.
  • the body fluid is limited to urine
  • the fluid discharge is limited to the urine discharge generated in the kidney and collected in the urine bag through the catheter.
  • the controller of the main body is preferably configured in the same manner as those of the first and second embodiments.
  • the kidney monitoring apparatus may be characterized by visually more easily identifying the correlation between urine discharge and event information and the correlation between urine discharge and drug injection information.
  • FIG. 3 is a graph illustrating an example of a screen output to a data output unit when the controller is driven in a third operation mode in the systems according to the first and third embodiments of the present invention.
  • the urine discharge or the fluid discharge amount Qv for the time t is output, and the events A, B, and C are output together on the graph, so that the change in the urine discharge or the fluid discharge for each event is determined. It's easy to see.
  • event A represents surgery
  • event B represents a first diuretic input
  • event C represents a second diuretic input.
  • FIG. 4 shows the first and third embodiments of the present invention.
  • it is a graph illustrating an example of a screen output to a data output unit when the controller is driven in the fourth operation mode.
  • the output per unit time for the time t (Flowrate; dQv / dt) is output, and the events A, B, and C are output together on the graph to easily identify the output per unit time for each event. It becomes possible.
  • an area that falls below the lower limit of the first reference range may be indicated by a first warning zone and a second zone.
  • FIG. 5 is a graph illustrating an example of a screen output to a data output unit when the controller is driven in a seventh operation mode in the systems according to the second and fourth embodiments of the present invention.
  • the urine discharge or the fluid discharge Qv for the time t is output, and the total injection amount Qi and the events A, B, and C for each time are output together on the graph, thereby providing an infusion regulator.
  • the total injection amount Qi and the events A, B, and C for each time are output together on the graph, thereby providing an infusion regulator.
  • FIG. 6 is a graph illustrating an example of a screen output to a data output unit when the controller is driven in an eighth operation mode in the systems according to the second and fourth embodiments of the present invention.
  • the output per unit time (Flowrate; dQv / dt), the injection amount per unit time (dQi / dt), and the events A, B, and C are outputted together on the time series graph by the infusion controller. It is easy to know the injection amount per unit time (dQi / dt) and the emission per unit time (dQv / dt) for each event.
  • the patient monitoring apparatus is characterized by including a body fluid collector, a body fluid collector state meter, an infusion controller, and a main body.
  • the patient monitoring apparatus according to the present embodiment is characterized by providing information for monitoring a patient's condition by using body fluid discharge information and drug injection information.
  • the bodily fluid collector, the bodily fluid collector state measuring device, and the infusion controller of the patient monitoring apparatus are the same as those of the above-described second embodiment, redundant description thereof will be omitted.
  • the main body of the patient monitoring apparatus according to the present embodiment is different from that of the above-described first to second embodiments in that the main body does not have a separate event input unit. ⁇
  • a body configured to generate bodily fluid discharge information using measurement data provided from the bodily fluid collector state meter, to generate drug injection information using the injection related information provided from the infusion controller, and to analyze the bodily fluid discharge information and the drug injection information;
  • the main body includes a signal input unit, a data output unit, and a controller for receiving measurement data in real time from a bodily fluid collector state meter or receiving injection related information from the injection controller in real time.
  • the control unit receives the measurement data in real time from the signal input unit, Generating bodily fluid discharge information using the measurement data, generating drug injection information using the injection related information provided from the infusion controller, analyzing the bodily fluid discharge information and the drug injection information, and outputting the analyzed results Output to the unit.
  • Body fluid discharge information and drug injection information according to the present embodiment are the same as those of the first and second embodiments.
  • the controller is operated in one of a plurality of operation modes by using body fluid discharge information and drug injection information. If the first operation mode is selected, the controller outputs the body fluid discharge amount and the injection amount per unit time for each detection time to the data output unit. If the second operation mode is selected, the controller extracts the discharge amount per unit time from the body fluid discharge information. Outputting the discharge amount per unit time and injection amount per unit time to a data output unit, and when the third operation mode is selected, outputs the body fluid discharge amount and total injection amount for each detection time to the data output unit, and the fourth operation mode If selected, the output per unit time is extracted from the body fluid discharge information, and the output per unit time and the total injection amount are output to the data output unit.
  • the patient monitoring device according to the present embodiment can be used as a kidney function monitoring device by being magnified in a urine bag as a body fluid bag.
  • the body fluid collector state measurer is for measuring the amount of body fluid stored in the body fluid collector, and may be variously measured through volume measurement, weight measurement, pressure measurement, length measurement, and the like.
  • the present embodiment is characterized in that the body fluid discharge is detected by measuring the load of the body fluid collector using a load cell.
  • An example of the bodily fluid collector may be a ur ine bag, and the urine bag condition meter of the embodiment 14 may measure and provide urine discharge collected in the urine bag.
  • the body fluid collector state meter 8 includes a cradle 810 for mounting the body fluid collector 1, a weight sensor 820 fixed to the housing 800, and an elastic member ( 830, a sensor protection member 840.
  • the cradle 810 is for mounting the body fluid collector 1, characterized in that to move along the direction of gravity by the load of the body fluid collector.
  • the weight sensor 820 may be configured as a strain gage, and is mounted on one surface of the housing or a support protruding from the housing. One end of the weight sensor is electrically connected to an external monitoring device, and a sensing signal output from the weight sensor is output to the outside.
  • the body fluid collector state meter is characterized by including an elastic member and a sensor protection member to prevent such damage.
  • the elastic member 830 may be composed of a spring, a swatch, or the like, and may prevent the external shock from being suddenly applied by the weight sensor.
  • the elastic member may be fixedly disposed between the upper surface of the weight sensor 820 and the upper frame of the cradle 810, the load of the cradle weight sensor To pass.
  • the sensor protection member 840 is preferably configured so that the movable range of the cradle does not deviate from a preset range, so as to prevent an overload from being added to the weight sensor.
  • the preset range may be determined by the rated load of the weight sensor.
  • the sensor protection member is composed of a guide bump protruding from the housing and is disposed at a predetermined height between the weight sensor and the upper frame of the cradle.
  • the installation height of the guide beam may be determined by the rated load of the weight sensor.
  • the bodily fluid collector state measuring device having the above-described structure is for measuring the bodily fluid collector weight, and when the bodily fluid collector is mounted on the lower frame of the cradle, the cradle descends along the direction of gravity as a whole according to the load of the bodily fluid collector.
  • the load of the cradle is transmitted to the weight sensor through the elastic member, and the weight sensor detects this and outputs a detection signal to the outside.
  • the housing mounting portion may be provided in the center of gravity of the upper portion of the housing, and the housing mounting portion may be mounted on a fixed surface such as a wall surface or a bed handle.
  • the housing mounting portion is provided with a hole in the center portion and is fixed so as to be able to move freely in the hole so that the housing can be freely rotated by gravity so that the center of the housing is always facing the increasing direction.
  • the bodily fluid collector condition meter described above can be used as the urine bag condition meter of the third and fourth embodiments.
  • Patient monitoring device and kidney monitoring device according to the present invention in the medical field because it can monitor the patient's state changes or renal function in real time in the case of drug or fluid infusion or specific surgery or procedure, etc. It can be widely used.

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Abstract

La présente invention concerne un dispositif permettant de surveiller la fonction rénale par mesure du volume de l'urine déchargée qui comprend : un appareil de mesure d'état de poche de recueil d'urine qui mesure l'état d'une poche de recueil d'urine à des moments d'échantillonnage prédéfinis, et fournit des données de mesure en temps réel ; un appareil de réglage d'injection qui fournit des informations en temps réel relatives aux injections impliquant l'injection de médicaments ou de transfusions à des patients ; et un corps principal qui génère des informations de décharge d'urine en utilisant les données mesurées par l'appareil de mesure d'état de poche de recueil d'urine, génère des informations d'injection de médicament et des informations d'événements, analyse les informations de décharge d'urine, les informations d'injection de médicaments et les informations d'événements, et affiche les résultats d'analyse sur un graphique chronologique et les transmet à une unité de sortie de données. Une unité de commande du corps principal analyse les informations de décharge d'urine, les informations d'injection de médicaments et les informations d'événements et délivre en sortie les résultats d'analyse sous la forme d'un graphique chronologique, permettant ainsi aux patients de vérifier en temps réel la corrélation entre la survenue d'événements ou l'injection de médicaments et le volume d'urine déchargée.
PCT/KR2015/000954 2014-04-04 2015-01-29 Dispositif de surveillance de patient et dispositif de surveillance de la fonction rénale WO2015152514A1 (fr)

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KR102198846B1 (ko) * 2018-06-29 2021-01-05 다인기술 주식회사 배뇨에 관한 설문을 수행하는 방법, 시스템 및 비일시성의 컴퓨터 판독 가능 기록 매체
KR102155354B1 (ko) 2018-07-16 2020-09-11 연세대학교 산학협력단 무선운용 멀티센싱 임플란트 및 이를 포함하는 고위험 노인질환 상시 모니터링 시스템
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