WO2015132432A1 - Implant dentaire artificiel - Google Patents

Implant dentaire artificiel Download PDF

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Publication number
WO2015132432A1
WO2015132432A1 PCT/ES2015/070127 ES2015070127W WO2015132432A1 WO 2015132432 A1 WO2015132432 A1 WO 2015132432A1 ES 2015070127 W ES2015070127 W ES 2015070127W WO 2015132432 A1 WO2015132432 A1 WO 2015132432A1
Authority
WO
WIPO (PCT)
Prior art keywords
bone
graft
face
jaw
artificial dental
Prior art date
Application number
PCT/ES2015/070127
Other languages
English (en)
Spanish (es)
Inventor
Francisco Javier RUIZ GINER
Original Assignee
Ruiz Giner Francisco Javier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ruiz Giner Francisco Javier filed Critical Ruiz Giner Francisco Javier
Publication of WO2015132432A1 publication Critical patent/WO2015132432A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2803—Bones for mandibular reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2875—Skull or cranium
    • A61F2002/2889—Maxillary, premaxillary or molar implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures

Definitions

  • the present invention can be included in the technical field of artificial dental grafts and more specifically it is an osteointegrable graft and not reabsorbed.
  • dental implants attach to the jaw bone. It is essential that this fixation be totally stable so that osseointegration is not lost due to mobility and poor lift. In these cases it is necessary to reconstruct the missing part of the bone and a reconstruction in the vertical direction or in the horizontal direction may be necessary, to have sufficient support for the implant. In other cases it may be necessary to restore part of the jaw to prevent the patient's own teeth from falling out of lack of support.
  • a generalized solution to these problems is to use an autologous bone, that is, the patient himself, to make a natural graft in the bone of the patient's jaw. You can also use animal bones to achieve this same goal. Autologous bones are usually used because this avoids possible incompatibility problems of the patient with the new bone grafted into his jaw. Other advantages of this type of graft are that it can preserve the matrix, with its bone-inducing properties and undifferentiated cells, and that it conserve vital cells, which are replaced by the host. They also do not induce any immune reaction. Small autogenous grafts can be obtained from the chin, and from the mandibular branch, the largest grafts, from the iliac crest.
  • the aim is to recover bone height and volume.
  • the corticomedular autograft of the iliac crest is the material that is generally used.
  • the biggest drawback of using natural bones to make grafts in patients' mouths is that they end up being reabsorbed. Over time it returns again to the same situation of lack of bone volume that was before the placement of the graft. In cases where the graft is reabsorbed, the implant is left with insufficient fixation.
  • the present invention describes an artificial dental graft of a biomaterial that is osseointegrated and that allows to restore bones of the oral cavity.
  • the artificial graft acts as part of the patient's own bone. It is specially designed to be used in cases in which the bone crest of a patient is not large enough in the oral jaws to accommodate endogenous support implants for the placement of dental prostheses.
  • Artificial grafting is used as a substitute for bone and dental roots respectively to help or complete the repair of skeletal deficiencies that may be due to trauma, tumor pathologies or abnormal development.
  • the graft allows to restore the normal function of the tissue and the dental pieces.
  • autologous bone grafts are currently used, that is, bones that are removed from another part of the patient's own body.
  • the artificial graft of the present invention is used in place of said autologous bones to prevent resorption. It is from a non-absorbable biomaterial but that is osseointegrated.
  • Osseointegration is a direct structural and functional connection between live, ordered bone, and the surface of an implant subjected to functional loading.
  • the graft is integrated with the alveolar bone, which is the bone that supports the natural tooth portion.
  • the graft be in direct contact with the bone, so that the process occurs naturally.
  • the graft of the invention replaces the part of the maxillofacial bone that the patient lacks. In most cases, the graft is used to achieve a larger surface area so that an implant can be placed on the patient. Implant placement requires sufficient support surface to ensure that it will remain fixed in position throughout the patient's life. In cases where the bone in which the implant has to be fixed is too thin or non-existent, the use of the graft of the invention is necessary.
  • the graft is modeled based on the shape and size calculated in the previous step and is manufactured using that exact data.
  • the grafts and all the necessary attachments for implantation in the patient's oral cavity are superficially treated and sterilized before performing the implant surgery on the patient.
  • the implant surface design is based on a porous trabecula that can be combined with a plasma rich in growth factors and / or with bone morphogenetic proteins that favor and accelerate your own bone growth.
  • This is osseointegration and occurs in the postimplantar phases, that is, after having placed the graft.
  • the artificial graft comprises through holes intended to receive means for joining the bone of the patient's jaw.
  • the connecting elements are threaded elements.
  • thread steps where the pillar implants are subsequently housed which are intended to support subsequent prostheses.
  • the graft thread steps are primarily intended to serve as a surgical guide in the placement of implants. Threaded stops are placed in the threaded passage housings that act as a limit for the surgical bits.
  • the secondary and main purpose of the graft threads is to serve as a mechanical stabilization for future endogenous implants, as well as to ensure, through a morse cone at the base, a biological seal that prevents bacterial colonization in compromised areas such as the implant-graft interface /bone.
  • threaded elements such as traspitelials, hollow or solid pillars can be connected, for the placement of manufacturing prostheses by conventional systems .
  • the graft of the invention acts as reinforcement throughout the jaw and allows the fixation of the implantomucosoported prosthesis.
  • the artificial graft can also be used to level the dentogingival line, increasing bone support (i.e., increasing bone surface) in patients who have gingival asymmetries.
  • the graft can be combined with gingivectomies or osteotomies if necessary. It is also used in recreations of the alveolar bone support.
  • the grafts are placed in the jaws of patients with acute and chronic periodontitis as dental support and to promote the regeneration of periodontal tissues.
  • the artificial graft is placed in the bone areas of the patient's jaw where part of the bone has been lost or is too thin. As it is not reabsorbable, once it joins the bone it no longer moves or becomes thinner or lost.
  • the proposed artificial graft osseointegrates and behaves as part of said bone to which it has been fixed.
  • It can also be used to perform large bone restructuring of the two jaws, placing one or more complementary grafts for the total recovery of the original support bone in complex maxillofacial surgeries.
  • the graft described is of a biomaterial that promotes cell adhesion, it can be combined with growth proteins that favor angiogenesis to consolidate the original periodontal fibers attached to the graft. The result is an artificial implant with all the biomechanical and functional characteristics of the original tooth.
  • the graft can also be used in palatoplasties (plastic surgery of the palate) as a definitive palatal obturator in patients who have cleft lip-alveolus-palatine.
  • This graft allows to operate early, reducing the surgical stages, with excellent aesthetic results. It does not slow the growth and normal development of the maxilla and prevents maxillary collapse and a satisfactory occlusion can be obtained. That is, with the conventional method only They make soft tissue grafts as obturation of the palatal fissure in several surgeries usually, while with the graft of the invention artificial bone support for the palatal mucosa is being placed in the palatal fissure in a single surgical act.
  • a further embodiment allows the artificial graft to be used as a housing for the slow and controlled release of drugs in the oral cavity.
  • the graft has at least one hollow cavity in which the drug is housed and a communication hole with the outside
  • Figure 1. Shows a perspective view of the graft in which the different parts of the graft body are observed.
  • Figure 2 - Shows a view in which the means of union of the body are observed to the jaw of a user.
  • Figure 3. Shows a view in which a graft with support projections is observed.
  • Figure 4.- Shows a view in which another example graft with support projections is observed.
  • the described artificial dental graft is intended to be fixed to the jaw bone of a user.
  • the objective is to be able to recover the original volume of said bone in a hollow of the jaw in which bone is missing or its volume has decreased.
  • This artificial graft comprises an osteointegrable and non-absorbable biomaterial body (1) that has a shape and size coinciding with the shape and size of the user's jaw hollow obtainable from a 3D image.
  • Each graft is in the corresponding jaw hole for which it is designed.
  • Figure 1 shows the body parts (1) of the implant.
  • said body (1) comprises a lingual / palatal face (2) intended to be oriented towards the lingual / palatal area, a vestibular face (3) opposite the lingual / palatal face (2), a basal face (5 ) intended to be in contact with the jaw bone and an occlusal face (6) opposite to said basal face (5).
  • the artificial graft comprises a plurality of microperforations (4) that cross the lingual / palatal face (2) and the anterior face (3) and that are configured to favor osseointegration in the jaw bone. As the biomaterial has osteoconductive characteristics, these multiple microperforations (4), induce the bone to grow through them, integrating the graft over time with the bone mass as a whole.
  • the occlusal face (6) of the body (1) is perforated with through holes (7) that also cross the basal face (5). These holes are intended for the placement and fixation of endogenous implants.
  • the graft additionally comprises joining means (9) that are configured to fix the body (1) to the jaw bone.
  • these joining means (9) are screws as shown in Figure 2.
  • the graft can also comprise depth limiters that have a hollow cylindrical configuration with a stop at its end. These limiters are arranged inside the holes (7) and are configured to limit the depth of said holes (7).
  • the doctor When an implant is to be placed to the graft user, the doctor has already marked the trajectory of the screw for the implant thanks to the depth limiters that allow limiting the depth of the bone drill used by the doctor for placement depending on the kind of endogenous implant planned for placement in each case.
  • the body (1) comprises on its occlusal face (6) support projections (8).
  • the artificial graft can additionally comprise a dental implant attached to the body (1) through the support projections (8).
  • the biomaterial with which the artificial graft of the The invention is a material comprising hydroxyapatite that is the main inorganic component of bones and is also present in dentin and tooth enamel.
  • Synthetic hydroxyapatite has a great chemical physical similarity to bone tissue and behaves like an osteoconductive structure that allows it to be invaded by connective tissue from the surrounding bone to later ossify, maintaining its original characteristics.
  • the artificial dental graft is used as a juxta or supraosseous graft prepared for the accommodation of an endogenous dental implant.
  • Figure 2 shows a biomaterial bone crest graft with the purpose of recovering the total volume of the jaw bone of the patient disappeared due to various causes, both vertically and horizontally.
  • the holes (7) are intended to receive endogenous implants of the same biomaterial as the graft body (1) or traditional titanium implants.
  • the implants connect the body (1) of the graft with the user's remaining bone.
  • joining means (9) which are in this case titanium or non-self-tapping screws of between 3 and 6 mm flat head for primary graft stability. They allow the body (1) of the graft to be attached to the remaining cortex in the vestibular / lingual / palatine areas.
  • the depth limiters in this case are made of titanium and have a different height depending on the implant that is to be arranged later attached to the graft. They allow to limit the pre-designed depth virtually of access of the surgical drill to the remaining bone, facilitating the surgeon the correct instrumentation, avoiding damaging important tissues (nerves, vessels, cortical, teeth, etc.).
  • the artificial dental graft is used as a juxta or supraosseous monoblock crest graft with built-in supports or stumps (8) that are configured for the conventional cementation of a fixed prosthesis .
  • This second embodiment also includes a body (1) intended to recover part of the missing bone from a user's jaw.
  • the body (1) comprises the projections or stumps (8) described above which are the supports for the placement of a future prosthesis.
  • the joining means (9) are as described for the first embodiment.
  • screwed or friction pins made of titanium or of the body's own biomatenal (1), which are transoseos and allow the vestibular / lingual / palatine face to be connected for greater stability and load distribution.
  • the graft is used as a periodontal graft.
  • the body (1) is a vestibular and lingual / palatal anatomical lamina of vertical bone support recovery of the dental socket. It is used in periodontal teeth with micro perforations at the level of the bone papillae on both sides to accommodate the titanium microvarillas.
  • An autologous fibrin clot is arranged between the graft and the dental root, as a scaffold for cell regeneration.
  • this third example there are also the same joining means (9) as in the first and second example, and additionally it comprises friction titanium microvarillas for the connection / fixation of the bone papillae of the graft.
  • the graft is used as a bone papilla graft as a support for mucous papilla.
  • the body (1) has a rounded pyramidal configuration.
  • the body (1) comprises additional micro perforations that are intended to accommodate impacted titanium rods as fixation to the interdental bone. remainder.
  • the graft is used as an intersinusal graft in "open sky" surgeries.
  • the graft has an elongated and flat configuration and is supported by the maxillary sinus bone and under the sinus membrane as a vertical bone augmentation for the support of threaded implants.
  • the joining means (9) are also flat head titanium screws.
  • the exact mold or shape of the graft is achieved by making a virtual simulation of the patient's bone in its optimal or ideal state at an early age. Thus the amount of graft necessary in its ideality, still in virtual phase, is obtained. Subsequently, using specialized software, machining / milling strategies are calculated on a precision machine with 5 continuous axes on a virgin biomaterial block. In this way the physical artificial graft object of virtual design is achieved.

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Manufacturing & Machinery (AREA)
  • Dental Prosthetics (AREA)

Abstract

L'invention concerne un implant dentaire artificiel conçu pour être fixé sur l'os de la mâchoire inférieure d'un patient dans le but de restaurer le volume original osseux dans un creux de la mâchoire inférieure dans lequel le volume osseux est insuffisant ou a diminué. L'implant artificiel comprend un corps (1) de biomatériau ostéo-intégrable et ne pouvant être réabsorbé, dont la forme et la taille correspondent à la forme et à la taille du creux présent dans la mâchoire inférieure du patient, qui peut être obtenu à partir d'une image 3D. L'invention permet ainsi d'obtenir un implant parfaitement adapté à la mâchoire inférieure du patient.
PCT/ES2015/070127 2014-03-04 2015-02-24 Implant dentaire artificiel WO2015132432A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201430290A ES2544904B1 (es) 2014-03-04 2014-03-04 Injerto artificial odontológico
ESP201430290 2014-03-04

Publications (1)

Publication Number Publication Date
WO2015132432A1 true WO2015132432A1 (fr) 2015-09-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2015/070127 WO2015132432A1 (fr) 2014-03-04 2015-02-24 Implant dentaire artificiel

Country Status (4)

Country Link
AR (1) AR103101A1 (fr)
ES (1) ES2544904B1 (fr)
UY (1) UY36017A (fr)
WO (1) WO2015132432A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3284441A1 (fr) * 2016-08-15 2018-02-21 Technische Universität Dresden Transplant permettant d'éliminer un défaut osseux de la mâchoire et procédé de fabrication du transplant
EP3725261A1 (fr) * 2019-04-15 2020-10-21 Trophy Procédé et appareil permettant d'aider un praticien dynamiquement dans la préparation d'une opération de greffe osseuse dentaire
CN111821048A (zh) * 2019-04-19 2020-10-27 李美桦 植牙手术导板及其制备方法
CN114366359A (zh) * 2022-02-10 2022-04-19 北京大学口腔医学院 适用于骨增量同期种植的数字化组合导板制作方法
US11364323B2 (en) 2018-09-17 2022-06-21 Rejuvablast LLC Combination grafts for tissue repair or regeneration applications

Citations (4)

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Publication number Priority date Publication date Assignee Title
US20050113930A1 (en) * 2003-02-26 2005-05-26 Therics, Inc. Method of manufacture, installation, and system for an alveolar ridge augmentation graft
CN102920535A (zh) * 2012-11-26 2013-02-13 北京爱康宜诚医疗器材股份有限公司 颌骨修复体
CN202960830U (zh) * 2012-11-26 2013-06-05 北京爱康宜诚医疗器材股份有限公司 颌骨修复体
US20130164707A1 (en) * 2011-12-22 2013-06-27 Mohamed Ikbal Ali Devices and methods for enhancing bone growth

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US4795475A (en) * 1985-08-09 1989-01-03 Walker Michael M Prosthesis utilizing salt-forming oxyacids for bone fixation
ES2129336B1 (es) * 1996-11-29 2000-04-01 Univ De A Coruna Protesis dental osteointegrable con implante y fijacion por levas y espigos.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050113930A1 (en) * 2003-02-26 2005-05-26 Therics, Inc. Method of manufacture, installation, and system for an alveolar ridge augmentation graft
US20130164707A1 (en) * 2011-12-22 2013-06-27 Mohamed Ikbal Ali Devices and methods for enhancing bone growth
CN102920535A (zh) * 2012-11-26 2013-02-13 北京爱康宜诚医疗器材股份有限公司 颌骨修复体
CN202960830U (zh) * 2012-11-26 2013-06-05 北京爱康宜诚医疗器材股份有限公司 颌骨修复体

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3284441A1 (fr) * 2016-08-15 2018-02-21 Technische Universität Dresden Transplant permettant d'éliminer un défaut osseux de la mâchoire et procédé de fabrication du transplant
US11364323B2 (en) 2018-09-17 2022-06-21 Rejuvablast LLC Combination grafts for tissue repair or regeneration applications
EP3725261A1 (fr) * 2019-04-15 2020-10-21 Trophy Procédé et appareil permettant d'aider un praticien dynamiquement dans la préparation d'une opération de greffe osseuse dentaire
WO2020214700A1 (fr) * 2019-04-15 2020-10-22 Carestream Dental Llc Procédé et appareil d'aide dynamique d'un praticien lors de la préparation d'une opération de greffe osseuse dentaire
CN111821048A (zh) * 2019-04-19 2020-10-27 李美桦 植牙手术导板及其制备方法
CN114366359A (zh) * 2022-02-10 2022-04-19 北京大学口腔医学院 适用于骨增量同期种植的数字化组合导板制作方法
CN114366359B (zh) * 2022-02-10 2024-03-12 北京大学口腔医学院 适用于骨增量同期种植的数字化组合导板制作方法

Also Published As

Publication number Publication date
ES2544904B1 (es) 2016-07-07
AR103101A1 (es) 2017-04-19
ES2544904A2 (es) 2015-09-04
ES2544904R1 (es) 2015-09-24
UY36017A (es) 2015-09-30

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