WO2015003779A3 - Vorrichtung und verfahren zur modellierung einer hornhaut - Google Patents
Vorrichtung und verfahren zur modellierung einer hornhaut Download PDFInfo
- Publication number
- WO2015003779A3 WO2015003779A3 PCT/EP2014/001791 EP2014001791W WO2015003779A3 WO 2015003779 A3 WO2015003779 A3 WO 2015003779A3 EP 2014001791 W EP2014001791 W EP 2014001791W WO 2015003779 A3 WO2015003779 A3 WO 2015003779A3
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- cornea
- finite element
- tissue sections
- distribution function
- element model
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- G—PHYSICS
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- G06F30/00—Computer-aided design [CAD]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F9/00825—Methods or devices for eye surgery using laser for photodisruption
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F30/00—Computer-aided design [CAD]
- G06F30/20—Design optimisation, verification or simulation
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
- A61B2034/101—Computer-aided simulation of surgical operations
- A61B2034/105—Modelling of the patient, e.g. for ligaments or bones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00853—Laser thermal keratoplasty or radial keratotomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00897—Scanning mechanisms or algorithms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/013—Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- General Engineering & Computer Science (AREA)
- Geometry (AREA)
- Evolutionary Computation (AREA)
- Optics & Photonics (AREA)
- Robotics (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- Databases & Information Systems (AREA)
- Vascular Medicine (AREA)
- Data Mining & Analysis (AREA)
- Primary Health Care (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Prostheses (AREA)
- Instructional Devices (AREA)
Abstract
Zur Modellierung einer Hornhaut für die Simulation von Gewebeschnitten in der Hornhaut, wird ein patientenspezifisches Finite Elemente Modell der Hornhaut erzeugt (S2). Im Finite Elemente Modell wird eine erste Gruppe von Gewebefasern, mit parallel zur Oberfläche der Hornhaut verlaufenden Hauptfasern, gemäss einer ersten Verteilungsfunktion verteilt (S22). Im Finite Elemente Modell wird überdies eine zweite Gruppe von Gewebefasern, mit inklinierten, nicht parallel zur Oberfläche der Hornhaut verlaufenden Crosslink-Fasern, gemäss einer zweiten Verteilungsfunktion verteilt (S23). Dabei verteilt (S23) die zweite Verteilungsfunktion die Crosslink-Fasern mit einer nicht uniformen Gewichtungsfunktion über die Tiefe der Hornhaut, von der äusseren Oberfläche der Hornhaut zur inneren Oberfläche der Hornhaut.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/903,674 US10181007B2 (en) | 2013-07-10 | 2014-06-30 | Device and method for modelling a cornea |
ES14736629.8T ES2665146T3 (es) | 2013-07-10 | 2014-06-30 | Dispositivo y procedimiento para el modelado de una córnea |
EP14736629.8A EP3019990B1 (de) | 2013-07-10 | 2014-06-30 | Vorrichtung und verfahren zur modellierung einer hornhaut |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20130003481 EP2824599A1 (de) | 2013-07-10 | 2013-07-10 | Vorrichtung und Verfahren zur Modellierung einer Hornhaut |
EP13003481.2 | 2013-07-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015003779A2 WO2015003779A2 (de) | 2015-01-15 |
WO2015003779A3 true WO2015003779A3 (de) | 2015-03-12 |
Family
ID=48793856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2014/001791 WO2015003779A2 (de) | 2013-07-10 | 2014-06-30 | Vorrichtung und verfahren zur modellierung einer hornhaut |
Country Status (4)
Country | Link |
---|---|
US (1) | US10181007B2 (de) |
EP (2) | EP2824599A1 (de) |
ES (1) | ES2665146T3 (de) |
WO (1) | WO2015003779A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
US10449090B2 (en) | 2015-07-31 | 2019-10-22 | Allotex, Inc. | Corneal implant systems and methods |
WO2017076698A1 (en) | 2015-11-05 | 2017-05-11 | Optimo Medical Ag | Method and device for modelling human or animal tissue |
TWI617284B (zh) * | 2016-11-08 | 2018-03-11 | 阿格斯醫材公司 | 眼角膜手術風險評估方法及其系統 |
CN108346472A (zh) * | 2017-01-24 | 2018-07-31 | 阿格斯医材公司 | 眼角膜手术风险评估方法及其系统 |
CN107766640B (zh) * | 2017-10-16 | 2020-06-30 | 北京理工大学 | 考虑微观组织界面的颗粒增强复合材料有限元建模方法 |
EP3764871A4 (de) | 2018-03-13 | 2021-12-15 | The UAB Research Foundation | Co-lokalisierte detektion von netzhautperfusion und sehnervenkopfdeformationen |
US20220133533A1 (en) * | 2019-02-26 | 2022-05-05 | Avedro, Inc. | Systems and Methods for Cross-Linking Treatments of an Eye |
AU2020270386A1 (en) | 2019-05-03 | 2021-12-02 | Lensar, Inc. | Cloud based system cataract treatment database and algorithm system |
CN113345065B (zh) * | 2021-08-04 | 2021-11-12 | 康达洲际医疗器械有限公司 | 一种基于指向性线段的曲面图像构建方法与系统 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5891131A (en) | 1993-02-01 | 1999-04-06 | Arizona Board Of Regents | Method and apparatus for automated simulation and design of corneal refractive procedures |
AU2001277038A1 (en) | 2000-07-21 | 2002-02-05 | Ohio State University | Methods and instruments for improving refractive ophthalmic surgery |
US7620147B2 (en) * | 2006-12-13 | 2009-11-17 | Oraya Therapeutics, Inc. | Orthovoltage radiotherapy |
US7496174B2 (en) * | 2006-10-16 | 2009-02-24 | Oraya Therapeutics, Inc. | Portable orthovoltage radiotherapy |
US7844425B2 (en) | 2008-01-18 | 2010-11-30 | Technolas Perfect Vision Gmbh | Finite element modeling of the cornea |
US20090318907A1 (en) | 2008-06-20 | 2009-12-24 | Bille Josef F | Generalized modeling of the cornea |
-
2013
- 2013-07-10 EP EP20130003481 patent/EP2824599A1/de not_active Withdrawn
-
2014
- 2014-06-30 EP EP14736629.8A patent/EP3019990B1/de active Active
- 2014-06-30 US US14/903,674 patent/US10181007B2/en active Active
- 2014-06-30 WO PCT/EP2014/001791 patent/WO2015003779A2/de active Application Filing
- 2014-06-30 ES ES14736629.8T patent/ES2665146T3/es active Active
Non-Patent Citations (3)
Title |
---|
ABAHUSSIN ET AL.: "3D collagen orientation study of the human cornea using X-ray diffraction and femtosecond laser technology.", INVEST OPHTHALMOL VIS SCI., vol. 50, no. 10, 10 June 2009 (2009-06-10), pages 5159 - 5164, XP002733940, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/pubmed/19516010> [retrieved on 20141217], DOI: doi: 10.1167/iovs.09-3669 * |
HARALD P. STUDER ET AL: "Patient-specific finite-element simulation of the human cornea: A clinical validation study on cataract surgery", JOURNAL OF BIOMECHANICS, vol. 46, no. 4, 1 February 2013 (2013-02-01), pages 751 - 758, XP055089802, ISSN: 0021-9290, DOI: 10.1016/j.jbiomech.2012.11.018 * |
STUDER H ET AL: "Biomechanical model of human cornea based on stromal microstructure", JOURNAL OF BIOMECHANICS, PERGAMON PRESS, NEW YORK, NY, US, vol. 43, no. 5, 22 March 2010 (2010-03-22), pages 836 - 842, XP026937973, ISSN: 0021-9290, [retrieved on 20100303], DOI: 10.1016/J.JBIOMECH.2009.11.021 * |
Also Published As
Publication number | Publication date |
---|---|
US20160162630A1 (en) | 2016-06-09 |
EP2824599A1 (de) | 2015-01-14 |
US10181007B2 (en) | 2019-01-15 |
EP3019990A2 (de) | 2016-05-18 |
WO2015003779A2 (de) | 2015-01-15 |
EP3019990B1 (de) | 2018-01-10 |
ES2665146T3 (es) | 2018-04-24 |
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