WO2014126351A1 - 치아 미백 조성물 - Google Patents
치아 미백 조성물 Download PDFInfo
- Publication number
- WO2014126351A1 WO2014126351A1 PCT/KR2014/000937 KR2014000937W WO2014126351A1 WO 2014126351 A1 WO2014126351 A1 WO 2014126351A1 KR 2014000937 W KR2014000937 W KR 2014000937W WO 2014126351 A1 WO2014126351 A1 WO 2014126351A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tartrate
- weight
- tooth
- parts
- whitening composition
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/38—Percompounds, e.g. peracids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/51—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Definitions
- a tooth whitening composition is disclosed. More specifically, a tooth whitening composition comprising tartrate is disclosed.
- tooth aesthetics are affected by the arrangement, size, color, texture and light transmittance of the tooth. Among these, tooth color is the most sensitive and important factor. It can also cause psychological problems.
- Tooth whitening is a treatment process that restores the enamel colored or discolored due to the pigment to the original color by using the pharmacological action of the whitening component.
- the coloring material may be removed by physical methods such as tooth cleaning, but the enamel layer or the ivory layer In the case of endogenous coloring that is penetrated and colored, it is difficult to remove the coloring material only by a physical method. Therefore, in addition to the physical method, a chemical method of removing the coloring material by infiltrating the dental whitening agent to the tooth surface is required.
- Conventional tooth whitening is performed using hydrogen peroxide or its precursor, carbamide peroxide.
- Hydrogen peroxide produces free radicals, and because these free radicals are chemically unstable and have electron affinity, whitening proceeds by combining with other organic molecules to obtain chemical stability and continuously generating free radicals.
- the free radicals are highly permeable to the tooth surface and easily move to the tooth surface to reach organic components attached to the enamel surface to oxidize the pigment molecules to convert them into small, pigmentless particles.
- Factors affecting the decomposition of hydrogen peroxide include temperature, pH, metal ions and light, and these factors have been known to promote the decomposition reaction of hydrogen peroxide.
- One embodiment of the present invention provides a tooth whitening composition comprising tartrate.
- a dental whitening composition comprising a dental whitening agent, a binder, tartrate and a solvent is provided.
- the dental whitening agent may include peroxide, hypochlorite, percarbonate, peroxide or a combination thereof.
- the binder may include a polymer.
- the polymer may have a number average molecular weight of 500,000 ⁇ 4,000,000.
- the tartrate may include monosodium tartrate, disodium tartrate, sodium ammonium tartrate, monopotassium tartrate, dipotassium tartrate, potassium sodium tartrate, calcium tartrate or combinations thereof.
- the solvent may comprise water, ethanol or a combination thereof.
- the tooth whitening composition may include 100 parts by weight of the dental whitening agent, 30 to 1,700 parts by weight of the binder, 0.3 to 350 parts by weight of the tartrate and 300 to 3,200 parts by weight of the solvent.
- the tooth whitening composition may further include a metal component, a pH adjuster or a combination thereof.
- the metal component may be derived from a metal salt.
- the metal salt may include iron salt, calcium salt, magnesium salt, copper salt or a combination thereof.
- the pH adjusting agent may include sodium hydroxide, sodium carbonate, sodium bicarbonate, potassium carbonate, tris (hydroxymethyl) aminomethane, triethanolamine, or a combination thereof.
- the amount of the dental whitening agent may be 3 to 35 parts by weight based on 100 parts by weight of the total weight of the tooth whitening composition.
- the tooth whitening composition according to the embodiment of the present invention includes tartrate, which has been proven to be safe as a food additive, so that it is harmless to the human body, and the reduction of metal ions present on the tooth surface, and thus inactivation of metal ions and metals By preventing the precipitation of the components to maintain a high pH of the tooth surface and improve the performance of tooth whitening by improving the penetration and decomposition ability of the dental whitening agent to the tooth surface.
- 1 is a photograph showing the whitening effect of the tooth whitening composition according to an embodiment of the present invention.
- FIG. 2 is a graph showing a change in brightness of teeth according to the number of times of whitening treatment when using the tooth whitening composition according to an embodiment of the present invention.
- a tooth bleaching composition according to one embodiment of the present invention includes a dental whitening agent, a binder, a tartrate and a solvent.
- the dental whitening agent After the dental whitening agent is decomposed, it serves to remove the coloring component by reacting with the coloring component (for example, protein) present on the tooth surface.
- the coloring component for example, protein
- the dental whitening agent may include peroxide, hypochlorite, percarbonate, peroxide or a combination thereof.
- the peroxide may include hydrogen peroxide, sodium peroxide, potassium peroxide, carbamide peroxide, sodium perborate, sodium percarbonate, or a combination thereof.
- the hypochlorite may include sodium hypochlorite, potassium hypochlorite, calcium hypochlorite, barium hypochlorite, or a combination thereof.
- the percarbonate may include sodium percarbonate, potassium percarbonate or a combination thereof.
- the peroxide may include acetic acid peroxide, monophosphate peroxide, diphosphate peroxide, monosulfate peroxide, persulfate peroxide, nitric peroxide or a combination thereof.
- the binder serves to bind the components of the tooth whitening composition. Accordingly, the tooth whitening composition may form a gel.
- the binder may include a polymer.
- the polymer may have a number average molecular weight of 500,000 ⁇ 4,000,000.
- the binder may include an ionic polymer, a nonionic polymer, or a combination thereof.
- the ionic polymer may include carboxymethyl cellulose, carboxypropyl cellulose, or a combination thereof.
- the nonionic polymer is polyvinyl alcohol, polyvinylpyrrolidone, hydroxyethyl cellulose, hydroxypropyl cellulose, polyacrylic acid, or a combination thereof. It may include.
- the tartrate is capable of reducing metal ions present on the tooth surface (e.g., reaction of metal ions with hydroxyl groups present on the tooth surface), and thereby inactivating the metal ions (i.e., degrading the dental whitening agent). Reduction) and to prevent the precipitation of metal. That is, the tartrate may be used as a chelating agent that forms a chemically stable chelate compound by coordinating with the metal ion. In addition, the tartrate prevents inactivation of the metal ions to maintain a high decomposition reaction rate of the dental whitening agent promoted by the metal ions, thereby increasing the concentration of the hydroxyl group generated by decomposition of the dental whitening agent.
- the pH of the tooth surface can be increased to maintain alkalinity and improve the teeth whitening effect.
- the tartrate prevents precipitation of the metal by the reduction of the metal ions (i.e., precipitation on the tooth surface), thereby facilitating the penetration of the dental whitening agent into the tooth surface, thereby decomposing the reaction rate of the dental whitening agent. It can be maintained high, thereby improving the teeth whitening effect.
- the tartrate is a food additive that is easily dissolved in an aqueous solution regardless of pH, so that it is easy to be formulated, and the human safety is proved.
- the tartrate may include monosodium tartrate, disodium tartrate, sodium ammonium tartrate, monopotassium tartrate, dipotassium tartrate, potassium sodium tartrate, calcium tartrate or combinations thereof.
- the solvent serves to dissolve at least the dental whitening agent and the binder.
- Such solvents may include water, ethanol or combinations thereof.
- the tooth whitening composition may include 100 parts by weight of the dental whitening agent, 30 to 1,700 parts by weight of the binder, 0.3 to 350 parts by weight of the tartrate and 300 to 3,200 parts by weight of the solvent.
- the viscosity of the tooth whitening composition is appropriate so that the whitening gel composition is not easily diluted or lost by saliva and the like, and is easy to the teeth. It can be applied, and may have excellent phase stability.
- the phase stability of the dental whitening agent in the tooth whitening composition may be excellent, and an excellent tooth whitening effect may be obtained.
- the tooth whitening composition may further include a metal component, a pH adjuster or a combination thereof.
- the metal component has affinity with the constituents of the enamel (eg, inorganic components), so that when the tooth whitening composition is applied to the tooth surface, it easily migrates towards the enamel. Accordingly, the metal component (particularly, metal ions) may increase the tooth whitening effect by helping to dissolve the dental whitening agent at or near the tooth surface to effectively remove the coloring component deep in the enamel. As such, the metal component promotes disintegration of the dental whitening agent to activate tooth whitening, and serves to enable fast and effective tooth whitening.
- the constituents of the enamel eg, inorganic components
- the metal component may be derived from a metal salt.
- Such metal components may include metal ions, core metals that form chelate compounds, or combinations thereof.
- the metal salt may include iron salt, calcium salt, magnesium salt, copper salt or a combination thereof.
- the present invention is not limited thereto, and the metal salt may include other transition metal salts and / or other alkali metal salts.
- the iron salt is iron (II) chloride, iron (III) chloride, iron bromide, iron sulfate, iron nitrate, iron acetate (II), iron propionate, iron citrate, iron gluconate, iron lactate, iron oxide, iron hydroxide, hydrates thereof, and these It may include at least one compound selected from the group consisting of ferric salts and ferrous salts of the mixture of.
- the magnesium salt may include magnesium phosphate, magnesium nitrate, magnesium acetate, magnesium chloride, magnesium carbonate, magnesium sulfate, magnesium gluconate, magnesium hydroxide, or a combination thereof.
- the copper salt includes copper pyrophosphate, copper sulfate, copper nitrate, copper acetate (II), copper chloride (I), copper chloride (II), copper carbonate (CuCO 3 ), copper gluconate, copper hydroxide, or a combination thereof. can do.
- the tooth whitening composition may have a metal ion concentration of 0.05-1 mM.
- the tooth whitening composition includes a chelating compound (ie, a complex formed by coordinating a tartrate to a metal ion), and the central metal of the chelate compound is also included in the calculation of the concentration of the metal ion. If the metal ion concentration is within the above range, an excellent tooth whitening effect can be obtained without the occurrence of additional coloring caused when excessive metal ions are present.
- the pH adjusting agent serves to promote decomposition of the dental whitening agent.
- pH adjusting agents may include sodium hydroxide, sodium carbonate, sodium bicarbonate, potassium carbonate, tris (hydroxymethyl) aminomethane, triethanolamine or combinations thereof.
- the content of the pH adjusting agent may be 1 to 20 parts by weight based on 100 parts by weight of the dental whitening agent.
- the content of the pH adjusting agent is within the range with respect to 100 parts by weight of the dental whitening agent, the pH of the tooth whitening composition is moderate, there is no risk of irritating the dental mucosa, the dental whitening agent is sufficiently decomposed to excellent tooth whitening effect Can be obtained.
- the tooth whitening composition may further comprise other additives such as flavors, hypersensitivity treatments, dental caries suppressants, gum disease ameliorating agents or combinations thereof.
- the fragrance may include peppermint, spearmint, citrus, herbs, menthol or a combination thereof.
- the hypersensitivity treatment agent is potassium nitrate (potassium nitrate), tin fluoride (stannous fluoride), sodium monofluoride phosphate (MFP), sodium fluoride (NaF: sodium fluoride), sodium fluoride (Na 2 SiF 6 : sodium silicofluoride) or a combination thereof.
- the dental caries suppressor may include sodium fluoride (NaF), calcium fluoride (CaF 2 ) or a combination thereof.
- the gum disease improving agent is bamboo salt, tocopherol acetate, vitamin D, allantoin chlorohydroxy aluminum, triclosan, xylitol, calcium glycophosphate, aminocaproic acid, KNO 3 , sodium monofluoro It may include phosphate (sodium monofluorophosphate), enzyme (enzyme) or a combination thereof.
- the amount of the other additives may be appropriately adjusted within a range capable of improving the usability and functionality of the tooth whitening composition without seriously changing the shape and stability of the tooth whitening composition.
- the amount of the dental whitening agent may be 3 to 35 parts by weight based on 100 parts by weight of the total weight of the tooth whitening composition.
- the content of the dental whitening agent is within the above range with respect to 100 parts by weight of the total weight of the tooth whitening composition, it is possible to obtain an excellent tooth whitening effect without fear of irritating the gingiva and oral mucosa.
- a tooth whitening composition was prepared by mixing 100 parts by weight of hydrogen peroxide, 166.7 parts by weight of polyacrylic acid (Sigma Aldrich, Carbomer, weight average molecular weight: 3,000,000), 33.3 parts by weight of monosodium tartrate and 3033.3 parts by weight of purified water. .
- a tooth whitening composition was prepared by mixing 100 parts by weight of hydrogen peroxide, 166.7 parts by weight of polyacrylic acid (Sigma Aldrich, Carbomer, weight average molecular weight: 3,000,000) and 3,000 parts by weight of purified water.
- each whitened tooth was visually observed to evaluate the whitening effect according to the VITA Shade Classical Guide.
- the tooth whitening composition was applied in the following manner: that is, each tooth whitening composition was applied to each tooth twice with a brush for 6 days.
- photographs of the teeth before the whitening treatment and the teeth after the whitening treatment were taken in FIG. 1.
- rows are teeth before the whitening treatment
- rows are the teeth after the whitening treatment.
- Example 1 Using the tooth whitening composition prepared in Example 1 and Comparative Examples 1 and 2, three white teeth having similar shade steps were subjected to a whitening treatment twice a day for 5 days, and then for 1 day compared to each non-whitening tooth. , 2 days, 3 days, 4 days and 5 days to measure the color change value ( ⁇ E * ab) of each tooth whitening treatment, the results are shown in Table 1 below.
- the tooth whitening composition was stored at a temperature of 37 °C during the whitening treatment period.
- the numerical value shown in Table 1 is a color change value ((DELTA) E * ab).
- a spectrophotometer (Spectro Color Meter SE-2000, Nippon Denshoku Industries Co., Ltd., Tokyo, Japan) was used as a measuring device of the color change value ( ⁇ E * ab).
- Example 1 Referring to Table 1, it was shown that the tooth whitening composition prepared in Example 1 is superior to the tooth whitening composition prepared in Comparative Examples 1 and 2.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
Description
미백 처리 일수 | 비교예 1 | 비교예 2 | 실시예 1 |
1일 | 1.5±0.7 | 1.8±1.5 | 4.2±1.6 |
2일 | 1.7±0.5 | 2.0±1.8 | 4.5±2.0 |
3일 | 1.8±0.8 | 2.2±2.6 | 4.9±2.6 |
4일 | 2.0±1.1 | 2.8±2.8 | 5.8±2.8 |
5일 | 2.9±1.1 | 3.3±3.5 | 6.2±3.5 |
Claims (12)
- 치과용 미백제, 바인더, 타트레이트 및 용매를 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 치과용 미백제는 과산화물, 하이포아염소산염, 과탄산염, 과산화산 또는 이들의 조합을 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 바인더는 고분자를 포함하는 치아 미백 조성물.
- 제3항에 있어서,상기 고분자는 500,000~4,000,000의 수평균분자량을 갖는 치아 미백 조성물.
- 제1항에 있어서,상기 타트레이트는 모노소듐 타트레이트, 디소듐 타트레이트, 소듐 암모늄 타트레이트, 모노포타슘 타트레이트, 디포타슘 타트레이트, 포타슘 소듐 타트레이트, 칼슘 타트레이트 또는 이들의 조합을 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 용매는 물, 에탄올 또는 이들의 조합을 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 치아 미백 조성물은 상기 치과용 미백제 100중량부, 상기 바인더 30~1,700중량부, 상기 타트레이트 0.3~350중량부 및 상기 용매 300~3,200중량부를 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 치아 미백 조성물은 금속 성분, pH 조절제 또는 이들의 조합을 더 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 금속 성분은 금속염으로부터 유래된 것인 치아 미백 조성물.
- 제9항에 있어서,상기 금속염은 철염, 칼슘염, 마그네슘염, 구리염 또는 이들의 조합을 포함하는 치아 미백 조성물.
- 제9항에 있어서,상기 pH 조절제는 소듐 히드록사이드, 소듐 카보네이트, 소듐 바이카보네이트, 포타슘 카보네이트, 트리스(히드록시메틸)아미노메탄, 트리에탄올아민 또는 이들의 조합을 포함하는 치아 미백 조성물.
- 제1항에 있어서,상기 치과용 미백제의 함량은 상기 치아 미백 조성물의 총 중량 100중량부에 대하여 3~35중량부인 치아 미백 조성물.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14752176.9A EP2957276B1 (en) | 2013-02-18 | 2014-02-04 | Dental bleaching composition |
US14/768,293 US20150374597A1 (en) | 2013-02-18 | 2014-02-04 | Dental bleaching composition |
JP2015557937A JP2016507584A (ja) | 2013-02-18 | 2014-02-04 | 歯牙美白組成物 |
CN201480009313.1A CN105025871A (zh) | 2013-02-18 | 2014-02-04 | 牙齿美白组合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2013-0016988 | 2013-02-18 | ||
KR20130016988A KR101493508B1 (ko) | 2013-02-18 | 2013-02-18 | 치아 미백 조성물 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014126351A1 true WO2014126351A1 (ko) | 2014-08-21 |
Family
ID=51354317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2014/000937 WO2014126351A1 (ko) | 2013-02-18 | 2014-02-04 | 치아 미백 조성물 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20150374597A1 (ko) |
EP (1) | EP2957276B1 (ko) |
JP (1) | JP2016507584A (ko) |
KR (1) | KR101493508B1 (ko) |
CN (1) | CN105025871A (ko) |
WO (1) | WO2014126351A1 (ko) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6494968B2 (ja) * | 2014-09-26 | 2019-04-03 | 株式会社ジーシー | 歯牙漂白用組成物 |
KR101831259B1 (ko) * | 2016-01-04 | 2018-02-23 | 오스템임플란트 주식회사 | 안정성이 향상된 치아 미백제 조성물 |
CN105616205A (zh) * | 2016-01-26 | 2016-06-01 | 浙江浙北药业有限公司 | 一种美白牙贴组合物 |
CN105616173A (zh) * | 2016-01-26 | 2016-06-01 | 浙江浙北药业有限公司 | 一种美白牙贴及其制备方法 |
KR102430222B1 (ko) * | 2017-11-28 | 2022-08-05 | 주식회사 엘지생활건강 | 치아 미백용 조성물 |
WO2023031025A1 (en) * | 2021-09-01 | 2023-03-09 | Unilever Ip Holdings B.V. | Oral care composition |
KR20230088163A (ko) * | 2021-12-10 | 2023-06-19 | 주식회사 엘지생활건강 | 공침물을 포함하는 치아 미백 촉진용 구강 조성물 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030152528A1 (en) * | 2001-05-01 | 2003-08-14 | Parminder Singh | Hydrogel compositions for tooth whitening |
KR20040095898A (ko) * | 2003-04-29 | 2004-11-16 | 애경산업(주) | 치아 미백용 첩포제 |
KR100550065B1 (ko) * | 2002-07-24 | 2006-02-08 | 주식회사 태평양 | 하이드로젤 매트릭스 부착 치아 미백용 패취 |
US20070065376A1 (en) * | 2005-09-20 | 2007-03-22 | Milton Hodosh | Method and composition for preventing tooth hypersensitivity when using passive bleaching agents |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU179164B (en) * | 1979-12-14 | 1982-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing cycloalkyl-ethers of alkanolamines |
US20060171907A1 (en) * | 1996-11-21 | 2006-08-03 | The Procter & Gamble Company | Oral care compositions providing enhanced whitening and stain prevention |
US6696043B2 (en) * | 2000-09-20 | 2004-02-24 | Scientific Pharmaceuticals, Inc. | Teeth whitening composition in the form of a chewing gum |
US6447757B1 (en) * | 2000-11-08 | 2002-09-10 | Scientific Pharmaceuticals, Inc. | Teeth whitening composition with increased bleaching efficiency and storage stability |
US6682722B2 (en) * | 2001-09-19 | 2004-01-27 | The Procter & Gamble Company | Oral compositions providing enhanced overall cleaning |
US7025950B2 (en) * | 2002-05-09 | 2006-04-11 | The Procter & Gamble Company | Oral care compositions comprising dicarboxy functionalized polyorganosiloxanes |
EP1555995B1 (en) * | 2002-10-31 | 2011-12-21 | Kao Corporation | Oral preparation and chewing gum |
KR100507675B1 (ko) * | 2003-05-30 | 2005-08-09 | 이상호 | 젤리형 치아미백용 패치 |
US20050143274A1 (en) * | 2003-12-17 | 2005-06-30 | Ghosh Chanchal K. | Compositions and methods of delivering bleaching agents to teeth |
US20050210615A1 (en) * | 2004-03-29 | 2005-09-29 | Ramachandra Shastry | Oral care method |
MX2007001031A (es) * | 2004-08-03 | 2009-02-11 | Unilever Nv | Composicion oral. |
US8956162B2 (en) * | 2005-04-11 | 2015-02-17 | Sylphar N.V. | Strip for the delivery of oral care compositions |
JP2009520829A (ja) * | 2005-12-20 | 2009-05-28 | ザ プロクター アンド ギャンブル カンパニー | 亜鉛およびフィチン酸塩を含む口腔ケア組成物 |
JP2007254419A (ja) * | 2006-03-24 | 2007-10-04 | Gc Corp | 歯科用漂白材 |
JP2008201732A (ja) * | 2007-02-21 | 2008-09-04 | Kao Corp | 歯の美白方法 |
CN101507689A (zh) * | 2009-04-02 | 2009-08-19 | 南昌普洋科技有限公司 | 用于牙齿漂白美白的凝胶 |
-
2013
- 2013-02-18 KR KR20130016988A patent/KR101493508B1/ko active IP Right Grant
-
2014
- 2014-02-04 US US14/768,293 patent/US20150374597A1/en not_active Abandoned
- 2014-02-04 CN CN201480009313.1A patent/CN105025871A/zh active Pending
- 2014-02-04 EP EP14752176.9A patent/EP2957276B1/en active Active
- 2014-02-04 JP JP2015557937A patent/JP2016507584A/ja active Pending
- 2014-02-04 WO PCT/KR2014/000937 patent/WO2014126351A1/ko active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030152528A1 (en) * | 2001-05-01 | 2003-08-14 | Parminder Singh | Hydrogel compositions for tooth whitening |
KR100550065B1 (ko) * | 2002-07-24 | 2006-02-08 | 주식회사 태평양 | 하이드로젤 매트릭스 부착 치아 미백용 패취 |
KR20040095898A (ko) * | 2003-04-29 | 2004-11-16 | 애경산업(주) | 치아 미백용 첩포제 |
US20070065376A1 (en) * | 2005-09-20 | 2007-03-22 | Milton Hodosh | Method and composition for preventing tooth hypersensitivity when using passive bleaching agents |
Also Published As
Publication number | Publication date |
---|---|
EP2957276B1 (en) | 2019-12-18 |
KR20140104530A (ko) | 2014-08-29 |
KR101493508B1 (ko) | 2015-02-16 |
CN105025871A (zh) | 2015-11-04 |
EP2957276A1 (en) | 2015-12-23 |
US20150374597A1 (en) | 2015-12-31 |
EP2957276A4 (en) | 2016-08-03 |
JP2016507584A (ja) | 2016-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2014126351A1 (ko) | 치아 미백 조성물 | |
KR101869109B1 (ko) | 치아 미백용 광활성화 가능한 산소 발생 조성물 및 방법 | |
EP1951184B1 (en) | Teeth whitening compositions and methods | |
EP2895139B1 (en) | Methods for teeth whitening | |
NL9500373A (nl) | Werkwijze voor het bereiden van een combinatiepreparaat voor het bleken van gebitselementen enerzijds en voor huid- en slijmvliesaandoeningen anderzijds alsmede toepassing daarvan. | |
WO2015076559A1 (ko) | 치아 미백 제품을 위한 구강 조성물 및 이를 포함하는 키트 | |
WO2000016737A1 (en) | Composition and method for whitening teeth without damaging soft tissue | |
WO2017119660A1 (ko) | 안정성이 향상된 치아 미백제 조성물 | |
WO2014126350A1 (ko) | 다부분 치아 미백 조성물 및 치아 미백 방법 | |
KR20140104529A (ko) | 치아 미백 조성물 및 치아 미백 방법 | |
US20220008301A1 (en) | Compositions and methods for reducing silver staining on teeth | |
US8277783B2 (en) | Permanganate containing whitening compositions and methods of their use | |
JP2004175766A (ja) | 美白用歯磨組成物 | |
CN104644476A (zh) | 一种能形成牙齿保护膜的漱口液 | |
WO2017109889A1 (ja) | 歯牙漂白用組成物及び歯牙の漂白方法 | |
WO2022113931A1 (ja) | 歯質強化方法及び歯のホワイトニング方法 | |
WO2023106810A1 (ko) | 공침물을 포함하는 치아 미백 촉진용 구강 조성물 | |
AU2015203605B2 (en) | Photoactivatable oxygen-evolving compositions and methods for teeth whitening | |
Mericle et al. | Studies concerning the antisolubility effectiveness of different stannous fluoride prophylaxis paste mixtures | |
Elmarakby | Dental Bleaching: How Far Distance between Patient Demands and what Actually Achieved | |
WO2022118254A1 (en) | Compositions comprising an iodide or thiocyanate, and methods for treating teeth | |
Fonseca | Basics of Compounding for Dentistry, Part 2: Tooth Whitening |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 201480009313.1 Country of ref document: CN |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 14752176 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 14768293 Country of ref document: US Ref document number: 2014752176 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2015557937 Country of ref document: JP Kind code of ref document: A |
|
NENP | Non-entry into the national phase |
Ref country code: DE |