WO2014097152A1 - Procédé de préparation du pazopanib ou de ses sels - Google Patents

Procédé de préparation du pazopanib ou de ses sels Download PDF

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Publication number
WO2014097152A1
WO2014097152A1 PCT/IB2013/061048 IB2013061048W WO2014097152A1 WO 2014097152 A1 WO2014097152 A1 WO 2014097152A1 IB 2013061048 W IB2013061048 W IB 2013061048W WO 2014097152 A1 WO2014097152 A1 WO 2014097152A1
Authority
WO
WIPO (PCT)
Prior art keywords
formula
compound
process according
pazopanib
salts
Prior art date
Application number
PCT/IB2013/061048
Other languages
English (en)
Inventor
Rajesh Kumar
Prabhat GIRI
Dhiren C. BARMAN
Asok Nath
Mohan Prasad
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Priority to EP13828826.1A priority Critical patent/EP2935250B1/fr
Priority to ES13828826.1T priority patent/ES2669425T3/es
Priority to US14/652,807 priority patent/US9802923B2/en
Publication of WO2014097152A1 publication Critical patent/WO2014097152A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

L'invention concerne un procédé de préparation du pazopanib de formule Ia ou de ses sels, et de ses intermédiaires.
PCT/IB2013/061048 2012-12-17 2013-12-17 Procédé de préparation du pazopanib ou de ses sels WO2014097152A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP13828826.1A EP2935250B1 (fr) 2012-12-17 2013-12-17 Procédé de préparation de pazopanib ou de sels de celui-ci
ES13828826.1T ES2669425T3 (es) 2012-12-17 2013-12-17 Procedimiento para la preparación de pazopanib o sales del mismo
US14/652,807 US9802923B2 (en) 2012-12-17 2013-12-17 Process for the preparation of pazopanib or salts thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
INDE38972012 2012-12-17
IN3897/DEL/2012 2012-12-17

Publications (1)

Publication Number Publication Date
WO2014097152A1 true WO2014097152A1 (fr) 2014-06-26

Family

ID=50070614

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/061048 WO2014097152A1 (fr) 2012-12-17 2013-12-17 Procédé de préparation du pazopanib ou de ses sels

Country Status (1)

Country Link
WO (1) WO2014097152A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107721989A (zh) * 2017-11-14 2018-02-23 苏州东南药业股份有限公司 一种帕唑帕尼的制备方法及其中间体
US10730859B2 (en) 2013-11-05 2020-08-04 Laurus Labs Limited Process for the preparation of pazopanib or a pharmaceutically acceptable salt thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106416A2 (fr) * 2002-06-17 2003-12-24 Smithkline Beecham Corporation Processus chimique
WO2005054212A2 (fr) * 2003-12-05 2005-06-16 Ciba Specialty Chemicals Holding Inc. Dispositif electroluminescent
US7105530B2 (en) 2000-12-21 2006-09-12 Smithkline Beecham Corporation Pyrimidineamines as angiogenesis modulators
WO2007064752A2 (fr) 2005-11-29 2007-06-07 Smithkline Beecham Corporation Procede de traitement
WO2011069053A1 (fr) 2009-12-04 2011-06-09 Teva Pharmaceutical Industries Ltd. Procede de preparation de pazopanip hcl et formes cristallines de pazopanib hcl
WO2012051659A1 (fr) * 2010-10-20 2012-04-26 Biota Scientific Management Pty Ltd Inhibiteurs d'une polymérase virale

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105530B2 (en) 2000-12-21 2006-09-12 Smithkline Beecham Corporation Pyrimidineamines as angiogenesis modulators
WO2003106416A2 (fr) * 2002-06-17 2003-12-24 Smithkline Beecham Corporation Processus chimique
WO2005054212A2 (fr) * 2003-12-05 2005-06-16 Ciba Specialty Chemicals Holding Inc. Dispositif electroluminescent
WO2007064752A2 (fr) 2005-11-29 2007-06-07 Smithkline Beecham Corporation Procede de traitement
WO2011069053A1 (fr) 2009-12-04 2011-06-09 Teva Pharmaceutical Industries Ltd. Procede de preparation de pazopanip hcl et formes cristallines de pazopanib hcl
WO2012051659A1 (fr) * 2010-10-20 2012-04-26 Biota Scientific Management Pty Ltd Inhibiteurs d'une polymérase virale

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DAVIES R R: "Indazole derivatives: the synthesis of various amino- and hydroxy-indazoles and derived sulphonic acids", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL SOCIETY, LETCHWORTH; GB, 1 January 1955 (1955-01-01), pages 2412 - 2423, XP009176650, ISSN: 0368-1769, DOI: 10.1039/JR9550002412 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10730859B2 (en) 2013-11-05 2020-08-04 Laurus Labs Limited Process for the preparation of pazopanib or a pharmaceutically acceptable salt thereof
US11299477B2 (en) 2013-11-05 2022-04-12 Laurus Labs Limited Process for the preparation of Pazopanib or a pharmaceutically acceptable salt thereof
US11427570B2 (en) 2013-11-05 2022-08-30 Laurus Labs Limited Process for the preparation of pazopanib or a pharmaceutically acceptable salt thereof
CN107721989A (zh) * 2017-11-14 2018-02-23 苏州东南药业股份有限公司 一种帕唑帕尼的制备方法及其中间体
CN107721989B (zh) * 2017-11-14 2019-06-14 苏州东南药业股份有限公司 一种帕唑帕尼的制备方法及其中间体

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