WO2014086753A2 - Composition comprenant des agents de lutte biologique - Google Patents

Composition comprenant des agents de lutte biologique Download PDF

Info

Publication number
WO2014086753A2
WO2014086753A2 PCT/EP2013/075326 EP2013075326W WO2014086753A2 WO 2014086753 A2 WO2014086753 A2 WO 2014086753A2 EP 2013075326 W EP2013075326 W EP 2013075326W WO 2014086753 A2 WO2014086753 A2 WO 2014086753A2
Authority
WO
WIPO (PCT)
Prior art keywords
hyl
spp
carboxamide
amino
rifluorome
Prior art date
Application number
PCT/EP2013/075326
Other languages
English (en)
Other versions
WO2014086753A3 (fr
Inventor
Wolfram Andersch
Bernd Springer
Wolfgang Thielert
Peter Lüth
Ute Eiben
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of WO2014086753A2 publication Critical patent/WO2014086753A2/fr
Publication of WO2014086753A3 publication Critical patent/WO2014086753A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/30—Microbial fungi; Substances produced thereby or obtained therefrom

Definitions

  • composition comprising biological control agents
  • the present invention relates to a composition
  • a composition comprising at least one biological control agent (I) selected from specific microorganisms and/or a mutant of these strains having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, nematodes and/or phytopathogens and at least one further biological control agent (II) which is selected from the group consisting of protozoas, viruses, entomopathogenic nematodes, and inoculants in a synergistically effective amount.
  • the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
  • Synthetic insecticides or fungicides often are non-specific and therefore can act on organisms other than the target ones, including other naturally occurring beneficial organisms. Because of their chemical nature, they may be also toxic and non- biodegradable. Consumers worldwide are increasingly conscious of the potential environmental and health problems associated with the residuals of chemicals, particularly in food products. This has resulted in growing consumer pressure to reduce the use or at least the quantity of chemical (i. e. synthetic) pesticides. Thus, there is a need to manage food chain requirements while still allowing effective pest control. A further problem arising with the use of synthetic insecticides or fungicides is that the repeated and exclusive application of an insecticide or fungicides often leads to selection of resistant microorganisms. Normally, such strains are also cross-resistant against other active ingredients having the same mode of action. An effective control of the pathogens with said active compounds is then not possible any longer. However, active ingredients having new mechanisms of action are difficult and expensive to develop.
  • Paecilomyces lilacinus strain 251 is known from WO 91 /02051 as biological nematicide. It was found in 1979 and is approved for use as a nematicide e.g. in Bulgaria and Italy as well as in Belgium. The strain has been isolated from a Meloidogyne egg mass in Los Banos, Philippines (cf. WO 91 /02051 ) and has been deposited with the Australian Government Analytical Laboratories (AGAL) in 1989 under the accession No. 89/030550.
  • WO 2009/1 1 61 06 relates to the strain Trichoderma atroviride SCI which is effective for biocontrol of fungal diseases in plants. It has first been isolated from decayed hazelnut wood in northern Italy in 2000 and has been deposited at the "Centraalbureeau voor Schimmelcultures" under the deposition number CBS No. 1 22089 in 2007.
  • a further known biological control agent is the strain Coniothyrium minitans CON/M/91 -08 (cf. WO 96/21 358) which has been deposited under the number DSM 9660 with the German Collection of Microorganisms and Cell Cultures in Braunschweig. It is used as a biological control against the fungal pathogens Sclerotinia sclerotiorum and Sclerotinia minor (causal agents of white mold on many plant species).
  • BCAs biological control agents
  • compositions which exhibit activity against insects, mites, nematodes and/or phytopathogens were provided.
  • it was a further particular object of the present invention to reduce the application rates and broaden the activity spectrum of the biological control agents, and thereby to provide a composition which, preferably at a reduced total amount of active compounds applied, has improved activity against insects, mites, nematodes and/or phytopathogens.
  • compositions according to the invention preferably fulfills the above-described needs. It has been discovered surprisingly that the application of the compositions according to the present invention in a simultaneous or sequential way to plants, plant parts, harvested fruits, vegetables and/or plant's locus of growth preferably allows better control of insects, mites, nematodes and/or phytopathogens than it is possible with one of the individual biological control agents and/or their mutants and/or their metabolites alone (synergistic mixtures).
  • the activity against insects, mites, nematodes and/or phytopathogens is preferably increased in a super additive manner.
  • the application of the composition according to the invention induces an increase in the activity against phytopathogens in a superadditive manner.
  • compositions according to the present invention preferably allow reduced total amounts of biological control agents to be used and thus the crops which have been treated by these compositions preferably show lowered amounts of residues in the crops treated with them. Further, the risk of resistance formation of animal pests is reduced.
  • the present invention is directed to a composition
  • a composition comprising at least one biological control agent (I) selected from the group consisting of Paecilomyces lilacinus strain 251 (AGAL No. 89/030550), Trichoderma atroviride SCI (CBS No.
  • Coniothyrium minitans CON/M/91 -08 DSM 9660
  • a mutant of these strains having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against nematodes, insects and/or phytopathogens, and at least one further biological control agent (II) which is selected from the group consisting of protozoas, viruses, entomopathogenic nematodes, and inoculants in a synergistically effective amount.
  • the present invention relates to a kit of parts comprising at least one of the specific biological control agents (I) and at least one of the biological control agent (II) .
  • the present invention is further directed to the use of said composition as pesticide. Moreover, i ⁇ is directed to the use of said composition for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, mites, nematodes and/or phytopathogens.
  • the present invention provides a method for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, mites, nematodes and/or phytopathogens.
  • pesticidal means the ability of a substance to increase mortality or inhibit the growth rate of plant pests.
  • the term is used herein, to describe the property of a substance to exhibit activity against insects, mites, nematodes and/or phytopathogens.
  • pests include insects, mites, nematodes and/or phytopathogens.
  • biological control is defined as control of a pathogen and/or insect and/or an acarid and/or a nematode by the use of a second organism.
  • Known mechanisms of biological control include bacteria that control root rot by out- competing fungi for space or nutrients on the surface of the root.
  • Bacterial toxins, such as antibiotics, have been used to control pathogens.
  • the toxin can be isolated and applied directly to the plant or the bacterial species may be administered so it produces the toxin in situ.
  • biological control as used in connection with the present invention may also encompass microorganisms having a beneficial effect on plant health, growth, vigor, stress response or yield.Application routes include spray application soil application and seed treatment.
  • metabolite refers to any compound, substance or byproduct of a fermentation of a said microorganism that has pesticidal activity.
  • mutant refers to a variant of the parental strain as well as methods for obtaining a mutant or variant in which the pesticidal activity is greater than that expressed by the parental strain.
  • the "parent strain” is defined herein as the original strain before mutagenesis. To obtain such mutants the parental strain may be treated wi ⁇ h a chemical such as N-me ⁇ hyl-N'-ni ⁇ ro-N-ni ⁇ rosoguanidine, ethylmethanesulfone, or by irradiation using gamma, x-ray, or UV-irradia ⁇ ion, or by other means well known to those skilled in the art.
  • a "variant” is a strain having all the identifying characteristics of the respective Accession Numbers as indicated in this text and can be identified as having a genome that hybridizes under conditions of high stringency to the genome of the respective Accession Numbers.
  • Hybridization refers to a reaction in which one or more polynucleotides react to form a complex that is stabilized via hydrogen bonding between the bases of the nucleotide residues.
  • the hydrogen bonding may occur by Watson-Crick base pairing, Hoogstein binding, or in any other sequence-specific manner.
  • the complex may comprise two strands forming a duplex structure, three or more strands forming a multi- stranded complex, a single self-hybridizing strand, or any combination of these.
  • Hybridization reactions can be performed under conditions of different "stringency". In general, a low stringency hybridization reaction is carried out at about 40 °C in 10 X SSC or a solution of equivalent ionic strength/temperature. A moderate stringency hybridization is typically performed at about 50 °C in 6 X SSC, and a high stringency hybridization reaction is generally performed at about 60 °C in 1 X SSC.
  • a variant of the indicated Accession Number may also be defined as a strain having a genomic sequence that is greater than 85%, more preferably greater than 90% or more preferably greater than 95% sequence identity to the genome of the indicated Accession Number.
  • a polynucleotide or polynucleotide region (or a polypeptide or polypeptide region) has a certain percentage (for example, 80%, 85%, 90%, or 95%) of "sequence identity" to another sequence means that, when aligned, that percentage of bases (or amino acids) are the same in comparing the two sequences. This alignment and the percent homology or sequence identity can be determined using software programs known in the art, for example, those described in Current Protocols in Molecular Biology (F. M. Ausubel et al., eds., 1987) Supplement 30, section 7. 7. 18, Table 7. 7. 1 .
  • AGAL is the abbreviation for "Australian Analytical Laboratories” which today is named “National Measurement Institute (NMI)” having the address 1 , Suakin Street, Pymble NSW 2073, Australia.
  • CBS is the abbreviation for "Centraalbureau voor Schimmelcultures", an international depositary authority for the purposes of deposing microorganism strains under the Budapest treaty on the international recognition of the deposit of microorganisms for the purposes of patent procedure, having the address Uppsalalaan 8, 3584 CT Utrecht, Netherlands.
  • DMS is the abbreviation for "Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH” located at Inhoffenstr. 78 in 38124 Braunschweig, Germany.
  • the biological control agents used in the present invention are known in the art as follows: Paecilomyces lilacinus strain 251
  • Paecilomyces lilacinus which was recently re-classified as Prupureocillium lilacinum, generally is a widely distributed saprophytic soil fungus which is readily isolatable throughout the world.
  • Paecilomyces lilacinus strain 251 (in the following sometimes referred to as Bl ) has been shown to be effective under field conditions against plant pathogenic or rather parasitic nematodes which attack a variety of agriculturally important crops including banana, potato, pineapple, cotton, coffee, rice, black pepper, okra, avocado, tomato etc. (WO 91 /02051 ) .
  • the combination according to the invention is effective against nematodes of the species Meloidogyne such as the Southern Root-Knot nematode (Meloidogyne incognita), Javanese Root-Knot nematode (Meloidogyne javanica), Northern Root- Knot Nematode (Meloidogyne hapla) and Peanut Root-Knot Nematode (Meloidogyne arenaria); nematodes of the species Ditylenchus such as Ditylenchus destructor and Ditylenchus dipsaci; nematodes of the species Pratylenchus such as the Cob Root-Lesion Nematode (Pratylenchus penetrans), Chrysanthemum Root- Lesion Nematode (Pratylenchus fallax), Pratylenchus coffeae, Pratylenchus loosi and Walnut Root-Lesion Nematode (Praty
  • Exemplary commercial products containing Paecilomyces lilacinus strain 251 are BioAct ® WG and MeloCon WG.
  • the activity of Paecilomyces lilacinus strain 251 is described inter alia in A. Khan et al., FEMS Microbiology Letters, 227, 1 07-1 1 1 , 2003 and S. Kiewnick at al. Biological Control 38, 1 79-187, 2006. Its isolation and characteristic properties are disclosed in WO 91 /02051 , which is incorporated herein by reference.
  • the strain has been deposited with the Australian Government Analytical Laboratories (AGAL) in 1 989 under the accession No. 89/030550.
  • AGAL Australian Government Analytical Laboratories
  • Paecilomyces lilacinus strain 251 of the invention is known and can be cultivated and caused to sporulate using methods well known in the art as described e.g. in WO 91 /02051 .
  • Harvesting of spores is preferably performed under conditions that do not promote heat, including shaking, scraping, washing and centrifugation.
  • the spore material is then dried by a suitable process such as air drying, freeze drying or desiccation with a suitable desiccant and can be reformulated by addition of inert filler or new growth material to provide a suitable number of spores per unit amount of product.
  • the strain is formulated on a carrier, preferably a water-soluble sugar carrier, in a concentration of between 1 x 1 0 5 and about 1 x 10 10 spores/g of carrier, preferably between 5 x 10 7 and about 5 x 1 0 9 spores/g carrier.
  • a carrier preferably a water-soluble sugar carrier
  • formulations up to about 1 x 1 0 10 spores/g, about 2 x 10 10 spores/g, about 5 x 1 0 10 spores/g, about 1 x 1 0 1 1 spores/g or even about 2 x 1 0" spores/g or about 3 x 1 0" spores/g may be obtained.
  • the carrier may e.g.
  • Paecilomyces lilacinus strain 251 may be formulated as a powder or in pelleted form. In this case the carrier is preferably formulated so that slow release of the spores is obtained over a considerable period of time following application.
  • the infective propagules of Paecilomyces lilacinus strain 251 may be applied to the crop either in liquid suspension, optionally in association with a suitable nematicidal carrier or, less preferred, as solid formulation, and in association with a suitable excipient.
  • the final dosage of infective propagules of Paecilomyces lilacinus starin 251 is normally in the order of between 1 x about 10 5 and about 1 x 1 0 7 , preferably between about 1 x 1 0 5 and about 1 x 1 0 6 spores per gram of soil for nursery applications and for field applications.
  • inventive composition may be applied to crops using any of the methods well known in the art. It may be advantageous to apply the inventive composition to the environment of the roots so minimizing the root damage caused by nematodes. This may be achieved by coating of the seeds with the inventive composition so that emergence of roots results in a fungal inoculum in their environment; by dipping or spraying the root regions of seedlings or seed trays in a nursery situation, or by application of the composition at the site of planting, either in aqueous suspension or in solid form. It is particularly preferred that the inventive composition is specifically applied to the regions of the plant rhizosphere affected by nematodes. The composition may be applied as a soil drench or through drip (trickle) or sprinkler (microjet) irrigation system.
  • Vegetables and other transplants can be treated just before transplanting with a soil drench to protect from nematodes entering the developing root ball in the field.
  • Nonfumigated field soils should be treated with the composition two weeks before seeding or transplanting to reduce initial nematode infestation.
  • Application can then be repeated e.g. at 6 weeks intervals.
  • the spores of Paecilomyces lilacinus strain 251 germinate upon contact with nematode eggs, juvenile stages and adults in the soil. The growing fungus engulfs and penetrates the nematode over a period of several days, killing it by consuming its body contents.
  • Paecilomyces lilacinus strain 251 is an obligate parasite of nematodes; it does not colonize the root or feed on root exudates. In the absence of nematodes, spores of Paecilomyces lilacinus strain 251 decline in the soil over a period of 3 to 6 weeks at a rate depending on soil type and temperature. According ⁇ o the invention Paecilomyces lilacinus strain 251 encompasses mutants having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against nematodes and/or insects. Trichoderma atroviride SCI
  • Trichoderma is a cosmopolitan fungal genus, which can colonize soils, rhizospheres and phyllospheres. Trichoderma species are frequently found on decaying wood and vegetable material. Several Trichoderma strains are economically important producers of industrial enzymes. Some Trichoderma strains have already been used as biocontrol agents against numerous plant pathogens and quite a few have been developed for use as commercial (i.e. Trichoderma harzianum, known as Trichodex® or Trianum ® , Trichoderma virens, known as SoilGard ® , and Trichoderma atroviride, known as Esquive ® ) biocontrol products for field and greenhouse crops.
  • Trichoderma harzianum known as Trichodex® or Trianum ®
  • Trichoderma virens known as SoilGard ®
  • Esquive ® Trichoderma atroviride
  • Trichoderma atroviride SCI (in the following sometimes referred to as B2) is known to suppress and to prevent the development of plant pathogens, in particular fruits and root rots, such as those caused by Botrytis cinerea and Armillaria spp., powdery mildews and wood diseases (Esca disease) (WO2009/1 1 61 06 which is incorporated herein by reference). It is deposited under the accession number CBS No. 122089.
  • Trichoderma atroviride SC I is a mesophilic fungus and able to utilize a wide range of compounds as carbon and nitrogen sources. Accordingly, it persists in soil at effective levels for long periods (more than one year) .
  • Trichoderma atroviride SCI compositions the spores are cultured by methods known to those skilled in the art.
  • Trichoderma atroviride SCI on a common nutrient substrate in liquid suspension or on solid substrate to obtain preferably at least 1 0 2 -1 0 3 conidia/(ml or g) (active concentration), preferably about 1 x 10 4 to about 1 x 1 0 8 conidia/(ml or g), which are then used in a composition preferably comprising an effective amount of this strain in a quantity of at least 10 2 -10 3 conidia/(ml or g), preferably about 1 x 1 0 4 1 x 1 0 8 conidia/(ml or g) .
  • Other cultivation methods are disclosed in WO2009/1 1 61 06.
  • a final concentration of conidia in the soil of between about 1 x 1 0 2 and about 1 x 1 0 5 spores/(ml or g) soil is envisaged.
  • the amount applied ranges between about 1 x 1 0" and about 1 x 10 13 spores/hectare, preferably about 1 x 10 12 spores/hectare
  • Plant treatment and/or prevention is carried out by using Trichoderma atroviride SCI cultures grown in liquid or semi-solid media or on a solid substrate and by applying this suspension onto parts of the plant or applying the enriched substrate on or into the sol in close proximity of the plant in need of such a treatment.
  • the treatment can be affected by applying agricultural compositions to plants, on the leaves of plants, on wounds made during cutting or pruning, or to the sol to suppress the development of fungal diseases on roots.
  • the treatment can be carried out during plant vegetative period or during dormancy.
  • the treatment can be applied once (i. e. at planting time in soil) or repeatedly as needed.
  • Trichoderma atroviride SCI encompasses mutants having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against pathogenic fungi.
  • Coniothyrium minitans strain CON/M/91 -08 The naturally occurring fungus Coniothyrium minitans has been first identified in 1947 and can be found in soils world-wide. It attacks and destroys the sclerotia (overwintering or survival structures) of Sclerotinia sclerotiorum and Sclerotinia minor, other Sclerotinia species and Sclerotium cepivorum. These pathogens have a wide host range of several hundered species of plants (including many vegetables and ornamentals). They commonly cause white mold on cole crops and beans, and are occasionally found on tomatoes and peppers. Additionally, they cause leaf drop on lettuce and white mold in carrots.
  • strain Coniothyrum minitans strain CON/M/91 -08 (in the following sometimes referred to as B3) is commercially available as Contans ® .
  • Coniothyrium minitans strain CON/M/91 -08 can be cultured as described in WO 96/21358 which is incorporated herein by reference.
  • this strain can be cultured on suitable substrates, such as seeds of grain, bran, straw or other plant materials, or also with the help of agar culture media that are customary in mycology, such as potato dextrose agar, or malt peptone agar, or on suitable support materials to which a culture medium has been added, as well as in liquid nutrient media without the addition of agar.
  • suitable substrates such as seeds of grain, bran, straw or other plant materials
  • agar culture media that are customary in mycology, such as potato dextrose agar, or malt peptone agar, or on suitable support materials to which a culture medium has been added, as well as in liquid nutrient media without the addition of agar.
  • the strain is formulated on a carrier, preferably a water-soluble sugar carrier, in a concentration of between 1 x 1 0 9 and about 1 x 10 15 spores/g of carrier, preferably between 1 x 1 0 10 and about 1 x 10 13 spores/g carrier. Most preferably, the concentration lies between about 1 x 1 0 8 and about 1 x 10 10 spores/g of carrier, such as at about 1 x 10 9 spores/g carrier.
  • the water-soluble sugar is glucose.
  • Coniothyrium minitans strain CON/M/91 -08 encompasses mutants having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against Sclerotinia spp., such as Sclerotinia sclerotiorum and/or Sclerotinia minor and/or Sclerotium cepivorum.
  • the biological control agent (I) comprises not only the isolated, pure culture(s) of the respective microorganism (s), but also their suspensions in a whole broth culture or a metabolite-containing supernatant or a purified metabolite obtained from whole broth culture of the strain.
  • Whole broth culture refers to a liquid culture containing both cells and media.
  • Supernatant refers to the liquid broth remaining when cells grown in broth are removed by centrifugation, filtration, sedimentation, or other means well known in the art.
  • the above-mentioned metabolites produced by the nonpathogenic microorganisms include antibiotics, enzymes, siderophores and growth promoting agents.
  • the biological control agent (I) may be employed or used in any physiologic state such as active or dormant.
  • the biological control agent (I) is Paecilomyces lilacinus strain 251 (AGAL No. 89/030550), and/or a mutant of this strain having all the identifying characteristics of this strain, and/or at least one metabolite produced by this strain that exhibits activity against nematodes, insects and/or phytopathogens.
  • this strain, its mutant and/or metabolite as defined above is preferred in case of the seed treatment and the seed treated with the composition according to the present invention.
  • the strain, its mutant and/or metabolite as defined above is used in soil or foliar applications.
  • Biological control agent (II) is selected from the group consisting of protozoas, viruses, entomopathogenic nematodes, and inoculants. Preferably, these terms encompass the following organisms and/or mutants of them having all identifying characteristics of the respective strain, and/or metabolites produced by the respective strain that exhibit activity against insects, mites, nematodes and/or phytopathogens.
  • biological control agents (II) that are summarized under the term "protozoas” are selected from the group consisting of (the numbering is used in the complete description) :
  • biological control agents (II) that are summarized under the term "viruses” are selected from the group consisting of (the numbering is used in the complete description) :
  • biological control agents (II) that are summarized under the term "entomopathogenic nematodes" are selected from the group consisting of (the numbering is used in the complete description) :
  • the invention biological control agents (II) that are summarized under the term "inoculants” are selected from the group consisting of (the numbering is used in the complete description) :
  • the biological control agent (II) comprises not only the isolated, pure cultures of the respective microorganisms, but also their suspensions in a whole broth culture or a metabolite-containing supernatant or a purified metabolite obtained from whole broth culture of the strain.
  • Whole broth culture refers to a liquid culture containing both cells and media.
  • Supernatant refers to the liquid broth remaining when cells grown in broth are removed by centrifugation, filtration, sedimentation, or other means well known in the art.
  • the above-mentioned metabolites produced by the nonpathogenic microorganisms include antibiotics, enzymes, siderophores and growth promoting agents.
  • the biological control agent (II) may be employed or used in any physiologic state such as active or dormant.
  • the term "at least one" indicates that in any case a substance as specified, such as a metabolite or a biological control agent other than Paecilomyces and Coniothyrium, is present in the composition according to the invention. However, more than one such as (at least) two, (at least) three, (at least) four, (at least) 5 or even more such substances may be present in the composition according to the invention.
  • the composition comprises the at least one biological control agent (I) and the at least one biological control agent (II) in a synergistically effective amount.
  • a “synergistically effective amount” represents a quantity of a combination of at least one biological control agent (I) and at least one biological control agent (II) that is statistically significantly more effective against insects, mites, nematodes and/or phytopathogens than the biological control agent (I) or the biological control agent (II) only.
  • fungicidal means fhe ability of a substance to increase mortality or inhibit the growth rate of fungi.
  • fungus or "fungi” includes a wide variety of nucleated sporebearing organisms that are devoid of chlorophyll. Examples of fungi include yeasts, molds, mildews, rusts, and mushrooms.
  • fungicide is selected so as not to have any fungicidal activity against the biological control agents according to the present invention.
  • the fungicide is selected from the group consisting of (1) Inhibitors of the ergosterol biosynthesis, for example (Fl) aldimorph (1704-28-5), (F2) azaconazole (60207-31-0), (F3) bitertanol (55179-31-2), (F4) bromuconazole (116255-48- 2), (F5) cyproconazole (113096-99-4), (F6) diclobutrazole (75736-33-3), (F7) difenoconazole (119446-68-3), (F8) diniconazole (83657-24-3), (F9) diniconazole-M (83657-18-5), (F10) dodemorph (1593-77-7), (FIT) dodemorph acetate (31717-87-0), (F12) epoxiconazole (106325-08-0), (F13) etaconazole (60207-93-4), (F14) fenarimol (60168-88-9
  • inhibitors of the respiratory chain at complex I or II for example (F65) bixafen (581809-46-3), (F66) boscalid (188425-85-6), (F67) carboxin (5234-68-4), (F68) diflumetorim (130339-07-0), (F69) fenfuram (24691 -80-3), (F70) fluopyram (658066-35-4), (F71 ) flutolanil (66332-96-5), (F72) fluxapyroxad (907204-31 -3), (F73) furametpyr (123572- 88-3), (F74) furmecyclox (60568-05-0), (F75) isopyrazam (mixture of syn-epimeric racemate 1 RS,4SR,9RS and anti-epimeric racemate 1 RS,4SR,9SR) (881685-58-1 ), (F76) isopyrazam (anti-epimeric racemate 1 RS
  • inhibitors of the respiratory chain at complex III for example (F105) ametoctradin (865318-97-4), (F106) amisulbrom (348635-87-0), (F107) azoxystrobin (131860-33-8), (F108) cyazofamid (1201 16-88-3), (F109) coumethoxystrobin (850881 -30-0), (Fl 10) coumoxystrobin (850881 -70-8), (Fi l l ) dimoxystrobin (141600-52-4), (Fl 12) enestroburin (238410-1 1 -2), (Fl 13) famoxadone (131807-57-3), (Fl 1 ) fenamidone (161326-34-7), (Fl 15) fenoxystrobin (9181 62-02-4), (Fl 16) fluoxastrobin (361377-29-9), (Fl 17) kresoxim- methyl (143390-89-0
  • Inhibitors of the mitosis and cell division for example (F138) benomyl (17804-35-2), (F139) carbendazim (10605-21-7), (F140) chlorfenazole (3574-96-7), (Fl 41 ) diethofencarb (87130-20-9), (F142) ethaboxam (162650-77-3), (F143) fluopicolide (239110-15-7), (F144) fuberidazole (3878-19-1), (F145) pencycuron (66063-05-6), (F146) thiabendazole (148-79-8), (F147) thiophanate-methyl (23564-05-8), (F148) thiophanate (23564-06-9), (F149) zoxamide (156052-68-5), (F150) 5-chloro-7-(4-me ⁇ hylpiperidin-l-yl)- 6-(2,4,6- ⁇ rifluorophenyl)[l,2,4] ⁇
  • Inhibitors of the ATP production for example (F198) fentin acetate (900-95-8), (F199) fentin chloride (639-58-7), (F200) fentin hydroxide (76-87-9), (F201) silthiofam (175217-20- 6);
  • Inhibitors of the cell wall synthesis for example (F202) benthiavalicarb (177406-68-7), (F203) dimethomorph (110488-70-5), (F204) flumorph (211867-47-9), (F205) iprovalicarb (140923-17-7), (F206) mandipropamid (374726-62-2), (F207) polyoxins (11113-80-7), (F208) polyoxorim (22976-86-9), (F209) validamycin A (37248-47-8), (F210) valifenalate (283159-94-4; 283159-90-0);
  • Inhibitors of the lipid and membrane synthesis for example (F211 ) biphenyl (92-52- 4), (F212) chloroneb (2675-77-6), (F213) dicloran (99-30-9), (F214) edifenphos (17109-49- 8), (F215) etridiazole (2593-15-9), (F216) iodocarb (55406-53-6), (F217) iprobenfos (26087-47-8), (F218) isoprothiolane (50512-35-1), (F219) propamocarb (25606-41-1), (F220) propamocarb hydrochloride (25606-41-1), (F221) prothiocarb (19622-08-3), (F222) pyrazophos (13457-18-6), (F223) quintozene (82-68-8), (F224) tecnazene (117-18-
  • Inhibitors of the melanine biosynthesis for example (F226) carpropamid (104030- 54-8), (F227) diclocymet (139920-32-4), (F228) fenoxanil (115852-48-7), (F229) phthalide (27355-22-2), (F230) pyroquilon (57369-32-1), (F231) tricyclazole (41814-78-2), (F232) 2,2,2-trifluoroethyl ⁇ 3-me ⁇ hyl-l-[(4-me ⁇ hylbenzoyl)amino]bu ⁇ an-2-yl ⁇ carbama ⁇ e (851524-22-6);
  • Inhibitors of the nucleic acid synthesis for example (F233) benalaxyl (71626-11-4), (F234) benalaxyl-M (kiralaxyl) (98243-83-5), (F235) bupirimate (41483-43-6), (F236) clozylacon (67932-85-8), (F237) dimethirimol (5221-53-4), (F238) ethirimol (23947-60-6), (F239) furalaxyl (57646-30-7), (F240) hymexazol (10004-44-1), (F241) metalaxyl (57837-19-
  • Inhibitors of the signal transduction for example (F246) chlozolinate (84332-86-5), (F247) fenpiclonil (74738-17-3), (F248) fludioxonil (131341-86-1), (F249) iprodione (36734-
  • fungicides of fhe classes (1) fo (16) i. e. Fl fo F380
  • fungicides of fhe classes (1) fo (16) can, if fheir functional groups enable this, optionally form salts with suitable bases or acids.
  • the fungicide is selected from fhe group consisting of
  • Inhibitors of fhe ergosterol biosynthesis for example (F3) bifertanol, (F4) bromuconazole (116255-48-2), (F5) cyproconazole (113096-99-4), (F7) difenoconazole (119446-68-3), (F12) epoxiconazole (106325-08-0), (F16) fenhexamid (126833-17-8), (F17) fenpropidin (67306-00-7), (F18) fenpropimorph (67306-03-0), (F19) fluquinconazole (136426-54-5), (F22) flufriafol, (F26) imazalil, (F29) ipconazole (125225-28-7), (F30) mefconazole (125116-23-6), (F31) myclobufanil (88671-89-0), (F37) penconazole (66246-88-6), (F39
  • inhibitors of fhe respiratory chain af complex I or II for example (F65) bixafen (581809-46-3), (F66) boscalid (188425-85-6), (F67) carboxin (5234-68-4), (F70) fluopyram (658066-35-4), (F71) flutolanil (66332-96-5), (F72) fluxapyroxad (907204-31-3), (F73) furamefpyr (123572-88-3), (F75) isopyrazam (mixture of syn-epimeric racemafe 1RS,4SR,9RS and anfi-epimeric racemafe 1RS,4SR,9SR) (881685-58-1), (F76) isopyrazam (anti-epimeric racemafe 1 RS,4SR,9SR), (F77) isopyrazam (anti-epimeric enanfiomer 1R,4S,9S), (F
  • inhibitors of the respiratory chain at complex III for example (F105) ametoctradin (865318-97-4), (F106) amisulbrom (348635-87-0), (F107) azoxystrobin (131860-33-8), (F108) cyazofamid (120116-88-3), (Fill) dimoxystrobin (141600-52-4), (Fl 12) enestroburin (238410-11-2), (Fl 13) famoxadone (131807-57-3), (Fl 1 ) fenamidone (161326-34-7), (Fl 16) fluoxastrobin (361377-29-9), (Fl 17) kresoxim-methyl (143390-89-0), (Fl 18) metominostrobin (133408-50-1), (Fl 19) orysastrobin (189892-69-1), (F120) picoxystrobin (117428-22-5), (Fl 21 pyraclostrobin
  • Inhibitors of the mitosis and cell division for example (F139) carbendazim (10605-21- 7), (F140) chlorfenazole (3574-96-7), (Fl 41 ) diethofencarb (87130-20-9), (F142) ethaboxam (162650-77-3), (F143) fluopicolide, (F144) fuberidazole (3878-19-1), (F145) pencycuron (66063-05-6), (F147) thiophanate-methyl (23564-05-8), (F149) zoxamide (156052-68-5);
  • Inhibitors of the amino acid and/or protein biosynthesis for example (F192) cyprodinil (121552-61-2), (F196) pyrimethanil (53112-28-0); (8) Inhibitors of the cell wall synthesis, for example (F202) benthiavalicarb ( 1 77406-68-7), (F203) dimethomorph ( 1 1 0488-70-5), (F205) iprovalicarb ( 140923-1 7-7), (F206) mandipropamid (374726-62-2), (F210) valifenalate (2831 59-94-4; 2831 59-90-0);
  • Inhibitors of the lipid and membrane synthesis for example (F21 6) iodocarb (55406- 53-6), (F21 7) iprobenfos (26087-47-8), (F220) propamocarb hydrochloride (25606-41 -1 ),
  • Inhibitors of the nucleic acid synthesis for example (F233) benalaxyl (71 626-1 1 -4), (F234) benalaxyl-M (kiralaxyl) (98243-83-5), (F239) furalaxyl (57646-30-7), (F240) hymexazol ( 10004-44-1 ), (F241 ) metalaxyl (57837-19-1 ), (F242) me ⁇ alaxyl-M (mefenoxam) (70630-1 7-0), (F244) oxadixyl (77732-09-3);
  • Inhibitors of the signal transduction for example (F247) fenpiclonil (74738-1 7-3), (F248) fludioxonil ( 131341 -86-1 ), (F249) iprodione (36734-19-7), (F251 ) quinoxyfen ( 124495-18-7), (F252) vinclozolin (50471 -44-8); (1 3) Compounds capable to act as an uncoupler, like for example (F256) fluazinam (79622-59-6);
  • the at least one fungicide e.g., the fungicide for use in seed treatment is selected from the group consisting of Carbendazim (F1 39), Carboxin (F67), Difenoconazole (F7), Fludioxonil (F248), Fluquinconazole (F19), Fluxapyroxad (F72), Ipconazole (F29), Isotianil (F187), Mefenoxam (F242), Metalaxyl (F241 ), Pencycuron (F1 45), Penflufen (F84), Prothioconazole (F41 ), Prochloraz (F39), Pyraclostrobin (F1 21 ), Sedaxane (F86), Silthiofam (F201 ), Tebuconazole (F47), Thiram (F1 82), Trifloxystrobin (F1 26), and Triticonazole (F55) .
  • Carbendazim F1 39
  • the fungicide used according to the present invention is a synthetic fungicide.
  • synthetic defines a compound that has no ⁇ been obtained from a natural source such as a plant, bacterium or other organism.
  • insects as well as the term “insecticidal” refers to the ability of a substance to increase mortality or inhibit growth rate of insects. As used herein, the term “insects” includes all organisms in the class “Insecta”. The term “pre-adult” insects refers to any form of an organism prior to the adult stage, including, for example, eggs, larvae, and nymphs.
  • nematodes and “nematicidal” refers to the ability of a substance to increase mortality or inhibit the growth rate of nematodes.
  • nematode comprises eggs, larvae, juvenile and mature forms of said organism.
  • Acaricide and “acaricidal” refers to the ability of a substance to increase mortality or inhibit growth rate of (ecto) parasites belonging to the class Arachnida, sub-class Acari.
  • the insecticides specified herein by their "common name” are known and described, for example, in the Pesticide Manual ("The Pesticide Manual", 15 ⁇ h Ed., British Crop Protection Council 2009) or can be searched in the internet (e.g. http://www.alanwood.net/pesticides).
  • Acetylcholinesterase (AChE) inhibitors for example carbamates, e.g. Alanycarb (II ), Aldicarb (12), Bendiocarb (13), Benfuracarb (14), Butocarboxim (15), Butoxycarboxim (16), Carbaryl (17), Carbofuran (18), Carbosulfan (19), Ethiofencarb (110), Fenobucarb (11 1 ), Formetanate (112), Furathiocarb (113), Isoprocarb (114), Methiocarb (115), Methomyl (116), Metolcarb (11 7), Oxamyl (118), Pirimicarb (119), Propoxur (120), Thiodicarb (121 ), Thiofanox (122), Triazamate (123), Trimethacarb (124), XMC (125), and Xylylcarb (126); or organophosphates, e.g.
  • AChE Acetylcholineste
  • Sodium channel modulators / voltage-dependent sodium channel blockers for example pyrethroids, e.g. Acrinathrin (196), Allethrin (197), d-cis- ⁇ rans Allethrin (198), d- trans Allethrin (199), Bifenthrin (1100), Bioallethrin (1101), Bioallethrin S-cyclopen ⁇ enyl isomer (1102), Bioresmethrin (1103), Cycloprothrin (1104), Cyfluthrin (1105), beta-Cyfluthrin (1106), Cyhalothrin (1107), lambda-Cyhalothrin (1108), gamma-Cyhalothrin (1109), Cypermethrin (1110), alpha-Cypermethrin (Nil), beta-Cypermethrin (1112), theta- Cypermethrin (II 13), zeta-Cypermethrin (1114), Cypheno
  • Nicotinic acetylcholine receptor (nAChR) allosteric activators for example spinosyns, e.g. Spinetoram (1150) and Spinosad (1151);
  • Chloride channel activators for example avermectins/milbemycins, e.g. Abamectin (1152), Emamectin benzoate (1153), Lepimectin (1154), and Milbemectin (1155); (7) Juvenile hormone mimics, for example juvenile hormon analogues, e.g. Hydroprene (1156), Kinoprene (1157), and Methoprene (1158); or Fenoxycarb (1159); or Pyriproxyfen (1160);
  • avermectins/milbemycins e.g. Abamectin (1152), Emamectin benzoate (1153), Lepimectin (1154), and Milbemectin (1155
  • Juvenile hormone mimics for example juvenile hormon analogues, e.g. Hydroprene (1156), Kinoprene (1157), and Methoprene (1158); or Fenoxycarb (1159); or Pyriproxyfen
  • Miscellaneous non-specific (multi-site) inhibitors for example alkyl halides, e.g. Methyl bromide (1161) and other alkyl halides; or Chloropicrin (1162); or Sulfuryl fluoride (II 63); or Borax (II 64); or Tartar emetic (1165);
  • alkyl halides e.g. Methyl bromide (1161) and other alkyl halides; or Chloropicrin (1162); or Sulfuryl fluoride (II 63); or Borax (II 64); or Tartar emetic (1165);
  • Mite growth inhibitors e.g. Clofentezine (1168), Hexythiazox (1169), and Diflovidazin (II 70); or Etoxazole (1171); (11) Microbial disruptors of insect midgut membranes, e.g. Bacillus thuringiensis subspecies israelensis (1172), Bacillus thuringiensis subspecies aizawai (1173), Bacillus thuringiensis subspecies kurstaki (1174), Bacillus thuringiensis subspecies tenebrionis (1175), and B.t. Microbial disruptors of insect midgut membranes, e.g. B.t.
  • crop proteins CrylAb, CrylAc, CrylFa, CrylA.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34 Abl/35Abl (II 76); or Bacillus sphaericus (II 77);
  • Inhibitors of mitochondrial ATP synthase for example Diafenthiuron (1178); or organotin miticides, e.g. Azocyclotin (1179), Cyhexatin (1180), and Fenbutatin oxide (1181); or Propargite (1182); orTetradifon (1183);
  • Uncouplers of oxidative phoshorylation via disruption of the proton gradient for example Chlorfenapyr (1184), DNOC (1185), and Sulfluramid (1186);
  • Nicotinic acetylcholine receptor (nAChR) channel blockers for example Bensultap (11 87), Cartap hydrochloride (11 88), Thiocyclam (11 89), and Thiosultap- sodium (1190);
  • Inhibitors of chitin biosynthesis type 0, for example Bistrifluron (1191 ), Chlorfluazuron (11 92), Diflubenzuron (11 93), Flucycloxuron (1194), Flufenoxuron (11 95), Hexaflumuron (11 96), Lufenuron (11 97), Novaluron (1198), Noviflumuron (1199), Teflubenzuron (1200), and Triflumuron (1201 );
  • Inhibitors of chitin biosynthesis type 1 , for example Buprofezin (1202);
  • Ecdysone receptor agonists for example Chromafenozide (1204), Halofenozide (1205), Methoxyfenozide (1206), and Tebufenozide (1207);
  • Octopamine receptor agonists for example Amitraz (1208);
  • Mitochondrial complex III electron transport inhibitors for example Hydramethylnon (1209); or Acequinocyl (1210); or Fluacrypyrim (121 1 );
  • METI acaricides e.g. Fenazaquin (1212), Fenpyroximate (1213), Pyrimidifen (1214), Pyridaben (1215), Tebufenpyrad (121 6), and Tolfenpyrad (121 7); or Rotenone (Derris) (1218);
  • Inhibitors of acetyl CoA carboxylase for example tetronic and tetramic acid derivatives, e.g. Spirodiclofen (1221 ), Spiromesifen (1222), and Spirotetramat (1223);
  • Mitochondrial complex IV electron transport inhibitors for example phosphines, e.g. Aluminium phosphide (1224), Calcium phosphide (1225), Phosphine (1226), and Zinc phosphide (1227); or Cyanide (1228);
  • Mitochondrial complex II electron transport inhibitors for example beta-ketonitrile derivatives, e.g. Cyenopyrafen (1229) and Cyflumetofen (1230);
  • Ryanodine receptor modulators for example diamides, e.g. Chlorantraniliprole (1231 ), Cyantraniliprole (1232), and Flubendiamide (1233); Further active ingredients with unknown or uncertain mode of action, for example Amidoflumet (1234), Azadirachtin (1235), Benclothiaz (1236), Benzoximate (1237), Bifenazate (1238), Bromopropylate (1239), Chinomethionat (1240), Cryolite (1241 ), Dicofol (1242), Diflovidazin (1243), Fluensulfone (1244), Flufenerim (1245), Flufiprole (1246), Fluopyram (1247), Fufenozide (1248), Imidaclothiz (1249), Iprodione (1250), Meperfluthrin (1251 ), Pyridalyl (1252), Pyrifluquinazon (1253), Tetramethylfluthrin (1254), and iodomethane (1250),
  • H-pyrazole-5-carboxamide 1310 (known from WO2010/069502), N-[2-( ⁇ erf- bu ⁇ ylcarbamoyl)-4-cyano-6-me ⁇ hylphenyl]-l -(3-chloropyridin-2-yl)-3- ⁇ [5- (frifluoromefhyl)-l H- ⁇ e ⁇ razol-l -yl] methyl ⁇ -!
  • H-pyrazole-5-carboxamide (131 1 ) (known from WO2010/069502), N-[2-( ⁇ er ⁇ -bu ⁇ ylcarbamoyl)-4-cyano-6-me ⁇ hylphenyl]-l -(3- chloropyridin-2-yl)-3- ⁇ [5-( ⁇ rifluorome ⁇ hyl)-2H- ⁇ e ⁇ razol-2-yl] methyl ⁇ -!
  • H-pyrazole-5- carboxamide (1312) (known from WO2010/069502), (1 E)-N-[(6-chloropyridin-3- yl)me ⁇ hyl]-N'-cyano-N-(2,2-difluoroe ⁇ hyl)e ⁇ han-imidamide (1313) (known from WO2008/009360), N-[2-(5-amino-l,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3- bromo-l-(3-chloropyridin-2-yl)-l H-pyrazole-5-carboxamide (1314) (known from CN102057925), and methyl 2-[3,5-dibromo-2-( ⁇ [3-bromo-l -(3-chloropyridin-2-yl)-l H- pyrazol-5-yl]carbonyl ⁇ amino)benzoyl]-2-e ⁇ hyl-
  • the insecticide is a synthetic insecticide.
  • the insecticide is selected from the group consisting of Abamectin (1152) , Acephate (127), Acetamiprid (1141), Acrinathrin (196), Afidopyropen (1278), Alpha-Cypermethrin (1111), Azadirachtin (1235), Bacillus firmus (1256), (Beta-Cyfluthrin (1106), Bifenthrin (1100), Buprofezin (1202), Clothianidin (1142), Chlorantraniliprole (1231), Chlorfenapyr (1184), Chlorpyrifos (135), Carbofuran (18), Cyantraniliprole (1232), Cyenopyrafen (1229), Cyflumentofen (1230), Cyfluthrin (1105), Cypermethrin (1110), Deltamethrin (1116), Diafenthiuron (1178),
  • One aspect of the present invention is to provide a composition as described above additionally comprising at least one auxiliary selected from the group consisting of extenders, solvents, spontaneity promoters, carriers, emulsifiers, dispersants, frost protectants, thickeners and adjuvants.
  • auxiliary selected from the group consisting of extenders, solvents, spontaneity promoters, carriers, emulsifiers, dispersants, frost protectants, thickeners and adjuvants.
  • formulations are referred to as formulations.
  • such formulations, and application forms prepared from them are provided as crop protection agents and/or pesticidal agents, such as drench, drip and spray liquors, comprising the composition of the invention.
  • the application forms may comprise further crop protection agents and/or pesticidal agents, and/or activity-enhancing adjuvants such as penetrants, examples being vegetable oils such as, for example, rapeseed oil, sunflower oil, mineral oils such as, for example, liquid paraffins, alkyl esters of vegetable fatty acids, such as rapeseed oil or soybean oil methyl esters, or alkanol alkoxylates, and/or spreaders such as, for example, alkylsiloxanes and/or salts, examples being organic or inorganic ammonium or phosphonium salts, examples being ammonium sulphate or diammonium hydrogen phosphate, and/or retention promoters such as dioctyl sulphosuccinate or hydroxypropylguar
  • formulations include water-soluble liquids (SL), emulsifiable concentrates (EC), emulsions in water (EW), suspension concentrates (SC, SE, FS, OD), water-dispersible granules (WG), granules (GR) and capsule concentrates (CS); these and other possible types of formulation are described, for example, by Crop Life International and in Pesticide Specifications, Manual on development and use of FAO and WHO specifications for pesticides, FAO Plant Production and Protection Papers - 173, prepared by the FAO/WHO Joint Meeting on Pesticide Specifications, 2004, ISBN: 9251048576.
  • the formulations may comprise active agrochemical compounds other than one or more active compounds of the invention.
  • the formulations or application forms in question preferably comprise auxiliaries, such as extenders, solvents, spontaneity promoters, carriers, emulsifiers, dispersants, frost protectants, biocides, thickeners and/or other auxiliaries, such as adjuvants, for example.
  • auxiliaries such as extenders, solvents, spontaneity promoters, carriers, emulsifiers, dispersants, frost protectants, biocides, thickeners and/or other auxiliaries, such as adjuvants, for example.
  • An adjuvant in this context is a component which enhances the biological effect of the formulation, without the component itself having a biological effect.
  • adjuvants are agents which promote the retention, spreading, attachment to the leaf surface, or penetration.
  • These formulations are produced in a known manner, for example by mixing the active compounds with auxiliaries such as, for example, extenders, solvents and/or solid carriers and/or further auxiliaries, such as, for example, surfactants.
  • the formulations are prepared either in suitable plants or else before or during the application.
  • Suitable for use as auxiliaries are substances which are suitable for imparting to the formulation of the active compound or the application forms prepared from these formulations (such as, e.g., usable crop protection agents, such as spray liquors or seed dressings) particular properties such as certain physical, technical and/or biological properties.
  • Suitable extenders are, for example, water, polar and nonpolar organic chemical liquids, for example from the classes of the aromatic and non-aromatic hydrocarbons (such as paraffins, alkyl benzenes, alkylnaphthalenes, chlorobenzenes), the alcohols and polyols (which, if appropriate, may also be substituted, etherified and/or esterified), the ketones (such as acetone, cyclohexanone), esters (including fats and oils) and (poly)ethers, the unsubstituted and substituted amines, amides, lactams (such as N-alkylpyrrolidones) and lactones, the sulphones and sulphoxides (such as dimethyl sulphoxide).
  • aromatic and non-aromatic hydrocarbons such as paraffins, alkyl benzenes, alkylnaphthalenes, chlorobenzenes
  • suitable liquid solvents are: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons such as cyclohexane or paraffins, for example petroleum fractions, mineral and vegetable oils, alcohols such as butanol or glycol and also their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethylformamide and dimethyl sulphoxide, and also water.
  • aromatics such as xylene, toluene or alkylnaphthalenes
  • chlorinated aromatics and chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride
  • aliphatic hydrocarbons
  • Suitable solvents are, for example, aromatic hydrocarbons, such as xylene, toluene or alkylnaphthalenes, for example, chlorinated aromatic or aliphatic hydrocarbons, such as chlorobenzene, chloroethylene or methylene chloride, for example, aliphatic hydrocarbons, such as cyclohexane, for example, paraffins, petroleum fractions, mineral and vegetable oils, alcohols, such as methanol, ethanol, isopropanol, butanol or glycol, for example, and also their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, for example, strongly polar solvents, such as dimethyl sulphoxide, and water.
  • aromatic hydrocarbons such as xylene, toluene or alkylnaphthalenes
  • chlorinated aromatic or aliphatic hydrocarbons such as chloro
  • Suitable carriers are in particular: for example, ammonium salts and ground natural minerals such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals, such as finely divided silica, alumina and natural or synthetic silicates, resins, waxes and/or solid fertilizers. Mixtures of such carriers may likewise be used.
  • Carriers suitable for granules include the following: for example, crushed and fractionated natural minerals such as calcite, marble, pumice, sepiolite, dolomite, and also synthetic granules of inorganic and organic meals, and also granules of organic material such as sawdust, paper, coconut shells, maize cobs and tobacco stalks.
  • Liquefied gaseous extenders or solvents may also be used. Particularly suitable are those extenders or carriers which at standard temperature and under standard pressure are gaseous, examples being aerosol propellants, such as halogenated hydrocarbons, and also butane, propane, nitrogen and carbon dioxide.
  • emulsifiers and/or foam-formers, dispersants or wetting agents having ionic or nonionic properties, or mixtures of these surface-active substances are salts of polyacrylic acid, salts of lignosulphonic acid, salts of phenolsulphonic acid or naphthalenesulphonic acid, polycondensates of ethylene oxide with fatty alcohols or with fatty acids or with fatty amines, with substituted phenols (preferably alkylphenols or arylphenols), salts of sulphosuccinic esters, taurine derivatives (preferably alkylta urates), phosphoric esters of polyethoxylated alcohols or phenols, fatty acid esters of polyols, and derivatives of the compounds containing sulphates, sulphonates and phosphates, examples being alkylaryl polyglycol ethers, alkylsulphonates, alkyl sulphates, arylsulphonates, protein hydrolys,
  • auxiliaries that may be present in the formulations and in the application forms derived from them include colorants such as inorganic pigments, examples being iron oxide, titanium oxide, Prussian Blue, and organic dyes, such as alizarin dyes, azo dyes and metal phthalocyanine dyes, and nutrients and trace nutrients, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.
  • colorants such as inorganic pigments, examples being iron oxide, titanium oxide, Prussian Blue, and organic dyes, such as alizarin dyes, azo dyes and metal phthalocyanine dyes, and nutrients and trace nutrients, such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.
  • Stabilizers such as low-temperature stabilizers, preservatives, antioxidants, light stabilizers or other agents which improve chemical and/or physical stability may also be present. Additionally present may be foam-formers or defoamers.
  • formulations and application forms derived from them may also comprise, as additional auxiliaries, stickers such as carboxymethylcellulose, natural and synthetic polymers in powder, granule or latex form, such as gum arabic, polyvinyl alcohol, polyvinyl acetate, and also natural phospholipids, such as cephalins and lecithins, and synthetic phospholipids.
  • additional auxiliaries include mineral and vegetable oils.
  • auxiliaries present in the formulations and the application forms derived from them.
  • additives include fragrances, protective colloids, binders, adhesives, thickeners, thixotropic substances, penetrants, retention promoters, stabilizers, sequestrants, complexing agents, humectants and spreaders.
  • the active compounds may be combined with any solid or liquid additive commonly used for formulation purposes.
  • Suitable retention promoters include all those substances which reduce the dynamic surface tension, such as dioctyl sulphosuccinate, or increase the viscoelasticity, such as hydroxypropylguar polymers, for example.
  • Suitable penetrants in the present context include all those substances which are typically used in order to enhance the penetration of active agrochemical compounds into plants. Penetrants in this context are defined in that, from the (generally aqueous) application liquor and/or from the spray coating, they are able to penetrate the cuticle of the plant and thereby increase the mobility of the active compounds in the cuticle. This property can be determined using the method described in the literature (Baur et al., 1 997, Pesticide Science 51 , 131 -152) .
  • Examples include alcohol alkoxylates such as coconut fatty ethoxylate ( 10) or isotridecyl ethoxylate ( 12), fatty acid esters such as rapeseed or soybean oil methyl esters, fatty amine alkoxylates such as tallowamine ethoxylate ( 15), or ammonium and/or phosphonium salts such as ammonium sulphate or diammonium hydrogen phosphate, for example.
  • alcohol alkoxylates such as coconut fatty ethoxylate ( 10) or isotridecyl ethoxylate ( 12)
  • fatty acid esters such as rapeseed or soybean oil methyl esters
  • fatty amine alkoxylates such as tallowamine ethoxylate ( 15)
  • ammonium and/or phosphonium salts such as ammonium sulphate or diammonium hydrogen phosphate, for example.
  • the formulations preferably comprise between 0.00000001 % and 98% by weight of active compound or, with particular preference, between 0.01 % and 95% by weight of active compound, more preferably between 0.5% and 90% by weight of active compound, based on the weight of the formulation.
  • the content of the active compound is defined as the sum of the at least one biological control agent (I) and the at least one biological control agent (II).
  • the active compound content of the application forms (crop protection products) prepared from the formulations may vary within wide ranges.
  • the active compound concentration of the application forms may be situated typically between 0.00000001 % and 95% by weight of active compound, preferably between 0.00001 % and 1 % by weight, based on the weight of the application form.
  • Application takes place in a customary manner adapted to the application forms. Kit of parts
  • kit of parts comprising the composition according to the present invention in a spatially separated arrangement.
  • the above-mentioned kit of parts further comprises at least one fungicide and/or insecticide, with the proviso that the fungicide and/or insecticide and the biological control agent (I) and (II) are not identical.
  • the fungicide and/or the insecticide are those mentioned above.
  • the fungicide and/or insecticide can be present either in the biological control agent (I) component of the kit of parts or in the biological control agent (II) component of the kit of parts being spatially separated or in both of these components.
  • the kit of parts according to the present invention can additionally comprises at least one auxiliary selected from the group consisting of extenders, solvents, spontaneity promoters, carriers, emulsifiers, dispersants, frost protectants, thickeners and adjuvants as mentioned above.
  • This at least one auxiliary can be present either in the biological control agent (I) component of the kit of parts or in the biological control agent (II) component of the kit of parts being spatially separated or in both of these components.
  • composition as described above is used for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, mites, nematodes and/or phytopathogens.
  • composition as described above increases the overall plant health.
  • plant health generally comprises various sorts of improvements of plants that are not connected to the control of pests.
  • advantageous properties are improved crop characteristics including: emergence, crop yields, protein content, oil content, starch content, more developed root system, improved root growth, improved root size maintenance, improved root effectiveness, improved stress tolerance (e.g.
  • tillering increase, increase in plant height, bigger leaf blade, less dead basal leaves, stronger tillers, greener leaf color, pigment content, photosynthetic activity, less input needed (such as fertilizers or water), less seeds needed, more productive tillers, earlier flowering, early grain maturity, less plant verse (lodging), increased shoot growth, enhanced plant vigor, increased plant stand and early and better germination.
  • improved plant health preferably refers to improved plant characteristics including: crop yield, more developed root system (improved root growth), improved root size maintenance, improved root effectiveness, tillering increase, increase in plant height, bigger leaf blade, less dead basal leaves, stronger tillers, greener leaf color, photosynthetic activity, more productive tillers, enhanced plant vigor, and increased plant stand.
  • improved plant health preferably especially refers to improved plant properties selected from crop yield, more developed root system, improved root growth, improved root size maintenance, improved root effectiveness, tillering increase, and increase in plant height.
  • composition according to the present invention on plant health as defined herein can be determined by comparing plants which are grown under the same environmental conditions, whereby a part of said plants is treated with a composition according to the present invention and another part of said plants is not treated with a composition according to the present invention. Instead, said other part is not treated at all or treated with a placebo (i.e., an application without a composition according to the invention such as an application without all active ingredients (i.e. without the biological control agents as described herein), or an application without a biological control agent (I) as described herein, or an application without a biological control agent (II) as described herein.
  • a placebo i.e., an application without a composition according to the invention such as an application without all active ingredients (i.e. without the biological control agents as described herein), or an application without a biological control agent (I) as described herein, or an application without a biological control agent (II) as described herein.
  • composition according to the present invention may be applied in any desired manner, such as in the form of a seed coating, soil drench, and/or directly in-furrow and/or as a foliar spray and applied either pre-emergence, post-emergence or both.
  • the composition can be applied to the seed, the plant or to harvested fruits and vegetables or to the soil wherein the plant is growing or wherein it is desired to grow (plant's locus of growth). Reducing the overall damage of plants and plant parts often results in healthier plants and/or in an increase in plant vigor and yield.
  • composition according to the present invention is used for treating conventional or transgenic plants or seed thereof.
  • a method for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes and/or phytopathogens comprising the step of simultaneously or sequentially applying the composition of the present invention and optionally at least one fungicide and/or insecticide on the plant, plant parts, harvested fruits, vegetables and/or plant's locus of growth in a synergistically effective amount.
  • the method of the present invention includes the following application methods, namely both of the at least one biological control agent (I) and the at least one biological control agent (II) mentioned before may be formulated into a single, stable composition with an agriculturally acceptable shelf life (so called “solo-formulation”), or being combined before or at the time of use (so called “combined-formulations").
  • the expression “combination” stands for the various combinations of the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide, in a solo-formulation, in a single "ready-mix” form, in a combined spray mixture composed from solo-formulations, such as a "tank-mix”, and especially in a combined use of the single active ingredients when applied in a sequential manner, i.e. one after the other within a reasonably short period, such as a few hours or days, e.g. 2 hours to 7 days.
  • the order of applying the composition according to the present invention is not essential for working the present invention.
  • the term “combination” also encompasses the presence of the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide on or in a plant to be treated or its surrounding, habitat or storage space, e.g. after simultaneously or consecutively applying the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide to a plant its surrounding, habitat or storage space.
  • the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide are employed or used in a sequential manner, it is preferred to treat the plants or plant parts (which includes seeds and plants emerging from the seed), harvested fruits and vegetables according to the following method: Firstly applying the at least one biological control agent (II) and optionally the at least one fungicide and/or insecticide on the plant or plant parts or the soil, and secondly applying the biological control agent (I) to the same plant or plant parts or the soil.
  • the time periods between the first and the second application within a (crop) growing cycle may vary and depend on the effect to be achieved.
  • the first application is done, especially, if the at least one fungicide and/or insecticide is present, to prevent an infestation of the plant or plant parts with insects, mites, nematodes and/or phytopathogens (this is particularly the case when treating seeds) or to combat the infestation with insects, mites, nematodes and/or phytopathogens (this is particularly the case when treating plants and plant parts) and the second application is done to prevent or control the infestation with insects, mites, nematodes and/or phytopathogens.
  • Control in this context means that the biological control agent is not able to fully exterminate the pests or phytopathogenic fungi but is able to keep the infestation on an acceptable level.
  • a very low level of residues of the at least one biological control agents, and optionally at least one fungicide and/or insecticide on the treated plant, plant parts, and the harvested fruits and vegetables can be achieved.
  • harvested fruits and vegetables with the composition according to the invention is carried out directly or by action on their surroundings, habitat or storage space using customary treatment methods, for example dipping, spraying, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, foaming, painting, spreading-on, watering (drenching), drip irrigating.
  • customary treatment methods for example dipping, spraying, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, foaming, painting, spreading-on, watering (drenching), drip irrigating.
  • the at least one biological control agent (I), the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide as solo-formulation or combined-formulations by the ultra-low volume method, or to inject the composition according to the present invention as a composition or as sole-formulations into the soil (in-furrow).
  • plant to be treated encompasses every part of a plant including its root system and the material - e.g., soil or nutrition medium - which is in a radius of at least 10 cm, 20 cm, 30 cm around the caulis or bole of a plant to be treated or which is at least 10 cm, 20 cm, 30 cm around the root system of said plant to be treated, respectively.
  • the amount of the biological control agent (I) which is used or employed in combination with at least one biological control agent (II), optionally in the presence of at least one fungicide and/or insecticide depends on the final formulation as well as size or type of the plant, plant parts, seeds, harvested fruits and vegetables to be treated.
  • the biological control agent (I) to be employed or used according to the invention is present in about 2 % to about 80 % (w/w), preferably in about 5 % to about 75 % (w/w), more preferably about 10 % to about 70 % (w/w) of its solo- formulation or combined- formulation with the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide.
  • Paecilomyces lilacinus strain 251 e.g. its spores are present in a solo-formulation or the combined-formulation in a concentration of at least 104 colony forming units per gram preparation (e. g.
  • cells/g preparation, spores/g preparation such as 104 - 101 1 cfu/g, preferably 105 - 1010 cfu/g, more preferably 107 - 108 cfu/g, such as 108 cfu/g, 109 cfu/g, 5 x 109 cfu/g, 1010 cfu/g or 5 x 1010 cfu/g, Trichoderma atroviride SCI e.g. its spores are present in a solo-formulation or the combined-formulation in a concentration of at least 101 colony forming units per gram preparation (e. g.
  • cells/g preparation, spores/g preparation such as 101 - 105 cfu/g, preferably 102 - 103 cfu/g, and Coniothyrium minitans CON/M/91 -08 e.g. its spores are present in a solo-formulation or the combined-formulation in a concentration of at least 105 colony forming units per gram preparation (e. g. cells/g preparation, spores/g preparation), such as 105 - 1017 cfu/g, preferably 107 - 1015 cfu/g, more preferably 1010 - 1013 cfu/g at the time point of applying the biological control agent on a plant or plant parts such as seeds, fruits or vegetables.
  • references to the concentration of biological control agents in form of, e.g., spores or cells - when discussing ratios between the amount of a preparation of at least one biological control agent (I) and the amount of the biological control agent (II) - are made in view of the time point when the biological control agent (I) is applied on a plant or plant parts such as seeds, fruits or vegetables.
  • the amount of the biological control agent (II) which is used or employed in combination with at least one biological control agent (I), optionally in the presence of at least one fungicide and/or insecticide depends on the final formulation as well as size or type of the plant, plant parts, seeds, harvested fruits and vegetables to be treated.
  • the biological control agent (II) to be employed or used according to ⁇ he invention is present in about 2 % to about 80 % (w/w), preferably in about 5 % to about 75 % (w/w), more preferably about 10 % to about 70 % (w/w) of its solo- formulation or combined- formulation with the at least one biological control agent (I), and optionally the at least one fungicide and/or insecticide.
  • the at least one biological control agent (I) and at least one biological control agent (II), and if present also the at least one fungicide and/or insecticide are used or employed in a synergistic weight ratio.
  • the skilled person is able to find out the synergistic weight ratios for the present invention by routine methods.
  • the skilled person understands that these ratios refer to the ratio within a combined-formulation as well as to the calculative ratio of the at least one biological control agent (I) described herein and the biological control agent (II) when both components are applied as mono-formulations to a plant to be treated.
  • the skilled person can calculate this ratio by simple mathematics since the volume and the amount of the biological control agent (I) and biological control agent (II), respectively, in a mono-formulation is known to the skilled person.
  • the ratio can be calculated based on the amount of the at least one biological control agent (II), at the time point of applying said component of a combination according to the invention to a plant or plant part and the amount of a biological control agent (I) shortly prior (e.g., 48 h, 24 h, 12 h, 6 h, 2 h, 1 h) or at the time point of applying said component of a combination according to the invention to a plant or plant part.
  • the application of the at least one biological control agent (I) and the at least one biological control agent (II) to a plant or a plant part can take place simultaneously or at different times as long as both components are present on or in the plant after the application(s).
  • the skilled person can determine the concentration of the biological control agent (II) on/in a plant by analysis known in the art, at the time point or shortly before the time point of applying the biological control agent (I).
  • the concentration of a biological control agent (I) can be determined using test which are also known in the art, at the time point or shortly before the time point of applying the biological control agent (II).
  • the synergistic weight ratio of the at least one biological control agent (l)/spore preparation and the at least one biological control agent (ll)/spore preparation lies in the range of 1 : 500 to 1000 : 1 , preferably in the range of 1 : 500 to 500 : 1 , more preferably in the range of 1 : 500 to 300 : 1 . It has to be noted that for compositions further comprising at least one insecticide and/or at least one fungicide these ratio ranges refer to the biological control agents/spore preparation (to be combined with at least one other biological control agent/spore preparation) of around 1010 cells/spores per gram preparation of said cells/spores.
  • a ratio of 100:1 means 100 weight parts of a biological control agent/spore preparation having a cell/ spore concentration of 1010 cells/spores per gram preparation and 1 weight parts of a biological control agent/spore preparation having a cell/ spore concentration of 1010 cells/spores per gram preparation are combined (either as a solo formulation, a combined formulation or by separate applications to plants so that the combination is formed on the plant).
  • the ratio relates to cells/spores per gram preparation or per seed.
  • the synergistic weight ratio of the at least one biological control agent (l)/spore preparation to the at least one biological control agent (II) is in the range of 1 : 100 to 20.000 : 1 , preferably in the range of 1 :50 to 10.000:1 or even in the range of 1 :50 to 1000:1 .
  • the mentioned ratios ranges refer to biological control agents/spore preparations of biological control agents of around 1010 cells or spores per gram preparation of said biological control agent.
  • the ratio relates to cells/spores per gram preparation or per seed.
  • the cell/spore concentration of preparations can be determined by applying methods known in the art. To compare weight ratios of the biological control agents/ spore preparations, the skilled person can easily determine the factor between a preparation having a biological control agent/spore concentration different from 1010 cells/spores per gram cell/spore preparation and a preparation having a biological control agen ⁇ / spore concentration of 1010 cells/spores per gram preparation to calculate whether a ratio of a biological control agent/spore preparation to the other biological control agent/spore preparation is within the scope of the above listed ratio ranges.
  • the concentration of the biological control agent after dispersal is at least 50 g/ha, such as 50 - 7500 g/ha, 50 - 2500 g/ha, 50 - 1500 g/ha; at least 250 g/ha (hectare), at least 500 g/ha or at least 800 g/ha.
  • composition to be employed or used according to the present invention may vary.
  • the skilled person is able to find the appropriate application rate by way of routine experiments.
  • the present invention therefore also relates in particular to a method for protecting seed and germinating plants from attack by pests, by treating the seed with at least one biological control agent (I) as defined above and/or a mutant of it having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, nematodes and/or phytopathogens and at least one biological control agent (II) as defined above and optionally at least one fungicide and/or insecticide of the invention.
  • at least one biological control agent (I) as defined above and/or a mutant of it having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, nematodes and/or phytopathogens
  • at least one biological control agent (II) as defined above and optionally at least one fungicide and/or insecticide of the invention.
  • the method of the invention for protecting seed and germinating plants from attack by pests encompasses a method in which the seed is treated simultaneously in one operation with the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insecticide. It also encompasses a method in which the seed is treated at different times with the at least one biological control agent (I) and the at least one biological control agent (II), and optionally the at least one fungicide and/or insectice.
  • the invention likewise relates to the use of the composition of the invention for treating seed for the purpose of protecting the seed and the resultant plant against insects, mites, nematodes and/or phytopathogens.
  • the invention also relates to seed which at the same time has been treated with at least one biological control agent (I) and at least one biological control agent (II), and optionally at least one fungicide and/or insecticide.
  • the invention further relates to seed which has been treated at different times with the at least one biological control agent (I) and the at least one biological control agent (II) and optionally the at least one fungicide and/or insecticide.
  • the individual active ingredients in the composition of the invention may be present in different layers on the seed.
  • the invention relates to seed which, following treatment with the composition of the invention, is subjected to a film-coating process in order to prevent dust abrasion of the seed.
  • compositions of the invention provide protection from insects, mites, nematodes and/or phytopathogens not only to the seed itself but also to the plants originating from the seed, after they have emerged. In this way, it may not be necessary to treat the crop directly at the time of sowing or shortly thereafter.
  • a further advantage is to be seen in the fact that, through the treatment of the seed with composition of the invention, germination and emergence of the treated seed may be promoted.
  • composition of the invention may also be used, in particular, on transgenic seed.
  • composition of the invention may be used in combination with agents of the signalling technology, as a result of which, for example, colonization with symbionts is improved, such as rhizobia, mycorrhiza and/or endophytic bacteria, for example, is enhanced, and/or nitrogen fixation is optimized.
  • agents of the signalling technology for example, colonization with symbionts is improved, such as rhizobia, mycorrhiza and/or endophytic bacteria, for example, is enhanced, and/or nitrogen fixation is optimized.
  • compositions of the invention are suitable for protecting seed of any variety of plant which is used in agriculture, in greenhouses, in forestry or in horticulture. More particularly, the seed in question is that of cereals (e.g. wheat, barley, rye, oats and millet), maize, cotton, soybeans, rice, potatoes, sunflower, coffee, tobacco, canola, oilseed rape, beets (e.g. sugar beet and fodder beet), peanuts, vegetables (e.g. tomato, cucumber, bean, brassicas, onions and lettuce), fruit plants, lawns and ornamentals.
  • cereals e.g. wheat, barley, rye, oats and millet
  • maize cotton, soybeans, rice, potatoes, sunflower, coffee, tobacco, canola, oilseed rape, beets (e.g. sugar beet and fodder beet)
  • peanuts e.g. tomato, cucumber, bean, brassicas, onions and lettuce
  • fruit plants
  • the seed in question here is that of plants which generally contain at least one heterologous gene that controls the expression of a polypeptide having, in particular, insecticidal and/or nematicidal properties.
  • heterologous genes in transgenic seed may come from microorganisms such as Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, Clavibacter, Glomus or Gliocladium.
  • the present invention is particularly suitable for the treatment of transgenic seed which contains at least one heterologous gene from Bacillus sp.
  • the heterologous gene in question comes from Bacillus thuringiensis.
  • the composition of the invention is applied alone or in a suitable formulation to the seed.
  • the seed is preferably treated in a condition in which its stability is such that no damage occurs in the course of the treatment.
  • the seed may be treated at any point in time between harvesting and sowing.
  • seed is used which has been separated from the plant and has had cobs, hulls, stems, husks, hair or pulp removed.
  • seed may be used that has been harvested, cleaned and dried to a moisture content of less than 15% by weight.
  • seed can also be used that after drying has been treated with water, for example, and then dried again.
  • compositions of the invention can be applied directly, in other words without comprising further components and without having been diluted.
  • suitable formulations and methods for seed treatment are known to the skilled person and are described in, for example, the following documents: US 4,272,417 A, US 4,245,432 A, US 4,808,430 A, US 5,876,739 A, US 2003/0176428 Al , WO 2002/080675 A 1 , WO 2002/028186 A2.
  • the combinations which can be used in accordance with the invention may be converted into the customary seed-dressing formulations, such as solutions, emulsions, suspensions, powders, foams, slurries or other coating compositions for seed, and also ULV formulations.
  • These formulations are prepared in a known manner, by mixing composition with customary adjuvants, such as, for example, customary extenders and also solvents or diluents, colorants, wetters, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, stickers, gibberellins, and also water.
  • customary adjuvants such as, for example, customary extenders and also solvents or diluents, colorants, wetters, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, stickers, gibberellins, and also water.
  • Colorants which may be present in the seed-dressing formulations which can be used in accordance with the invention include all colorants which are customary for such purposes. In this context it is possible to use not only pigments, which are of low solubility in water, but also water-soluble dyes. Examples include the colorants known under the designations Rhodamin B, C.I. Pigment Red 1 12 and C.I. Solvent Red 1 .
  • Wetters which may be present in the seed-dressing formulations which can be used in accordance with the invention include all of the substances which promote wetting and which are customary in the formulation of active agrochemical ingredients. Use may be made preferably of alkylnaphthalenesulphonates, such as diisopropyl- or diisobutyl-naphthalenesulphonates.
  • Dispersants and/or emulsifiers which may be present in the seed-dressing formulations which can be used in accordance with the invention include all of the nonionic, anionic and cationic dispersants that are customary in the formulation of active agrochemical ingredients. Use may be made preferably of nonionic or anionic dispersants or of mixtures of nonionic or anionic dispersants.
  • Suitable nonionic dispersants are, in particular, ethylene oxide-propylene oxide block polymers, alkylphenol polyglycol ethers and also tristryrylphenol polyglycol ethers, and the phosphated or sulphated derivatives of these.
  • Suitable anionic dispersants are, in particular, lignosulphonates, salts of polyacrylic acid, and arylsulphonate- formaldehyde condensates.
  • Antifoams which may be present in the seed-dressing formulations which can be used in accordance with the invention include all of the foam inhibitors that are customary in the formulation of active agrochemical ingredients. Use may be made preferably of silicone antifoams and magnesium stearate.
  • Preservatives which may be present in the seed-dressing formulations which can be used in accordance with the invention include all of the substances which can be employed for such purposes in agrochemical compositions. Examples include dichlorophen and benzyl alcohol hemiformal.
  • Secondary thickeners which may be present in the seed-dressing formulations which can be used in accordance with the invention include all substances which can be used for such purposes in agrochemical compositions. Those contemplated with preference include cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and highly disperse silica.
  • Stickers which may be present in the seed-dressing formulations which can be used in accordance with the invention include all customary binders which can be used in seed-dressing products. Preferred mention may be made of polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and tylose.
  • the gibberellins are known (cf. R. Wegler, "Chemie der convinced für Schweizer- und Schadlingsbekampfungsstoff", Volume 2, Springer Verlag, 1970, pp. 401 -412).
  • the seed-dressing formulations which can be used in accordance with the invention may be used, either directly or after prior dilution with water, to treat seed of any of a wide variety of types.
  • the concentrates or the preparations obtainable from them by dilution with water may be employed to dress the seed of cereals, such as wheat, barley, rye, oats and triticale, and also the seed of maize, rice, oilseed rape, peas, beans, cotton, sunflowers and beets, or else the seed of any of a very wide variety of vegetables.
  • the seed-dressing formulations which can be used in accordance with the invention, or their diluted preparations, may also be used to dress seed of transgenic plants. In that case, additional synergistic effects may occur in interaction with the substances formed through expression.
  • suitable mixing equipment includes all such equipment which can typically be employed for seed dressing. More particularly, the procedure when carrying out seed dressing is to place the seed in a mixer, to add the particular desired amount of seed-dressing formulations, either as such or following dilution with water beforehand, and to carry out mixing until the distribution of the formulation on the seed is uniform. This may be followed by a drying operation.
  • the application rate of the seed-dressing formulations which can be used in accordance with the invention may be varied within a relatively wide range. It is guided by the particular amount of the at least one biological control agent (I) and the at least one biological control agent (II) in the formulations, and by the seed.
  • the application rates in the case of the composition are situated generally at between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 15 g per kilogram of seed.
  • composition according to the invention in case the at least one of the biological control agents exhibits insecticidal and nematicidal activity, in combination with good plant tolerance and favourable toxicity to warm-blooded animals and being tolerated well by the environment, are suitable for protecting plants and plant organs, for increasing harvest yields, for improving the quality of the harvested material and for controlling animal pests, in particular insects, arachnids, helminths, nematodes and molluscs, which are encountered in agriculture, in horticulture, in animal husbandry, in forests, in gardens and leisure facilities, in protection of stored products and of materials, and in the hygiene sector. They can be preferably employed as plant protection agents.
  • the present invention relates to the use of the composition according to the invention as pesticide.
  • pests from the phylum Arthropoda especially from the class Arachnida, for example, Acarus spp., Aceria sheldoni, Aculops spp., Aculus spp., Amblyomma spp., Amphitetranychus viennensis, Argas spp., Boophilus spp., Brevipalpus spp., Bryobia graminum, Bryobia praetiosa, Centruroides spp., Chorioptes spp., Dermanyssus gallinae, Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermacentor spp., Eotetranychus spp., Epitrimerus pyri, Eutetranychus spp., Eriophyes spp.,
  • Blaffodea for example, Blaffella asahinai, Blaffella germanica, Blaffa orienfalis, Leucophaea maderae, Panchlora spp., Parcoblaffa spp., Periplanefa spp., Supella longipalpa; from fhe order Coleopfera, for example, Acalymma viffafum, Acanfhoscelides obfecfus, Adorefus spp., Agelasfica alni, Agriofes spp., Alphifobius diaperinus, Amphimallon solsfifialis, Anobium puncfafum, Anoplophora spp., Anfhonomus spp., Anfhrenus spp., Apion spp., Apogonia spp., Afomaria spp., Affagenus
  • composition according to the present invention preferably has potent microbicidal activity and can be used for control of unwanted microorganisms, such as fungi and bacteria, in crop protection and in the protection of materials.
  • the invention also relates to a method for controlling unwanted microorganisms, characterized in that the inventive composition is applied to the phytopathogenic fungi, phytopathogenic bacteria and/or their habitat.
  • Fungicides can be used in crop protection for control of phytopathogenic fungi. They are characterized by an outstanding efficacy against a broad spectrum of phytopathogenic fungi, including soilborne pathogens, which are in particular members of the classes Plasmodiophoromycetes, Peronosporomycetes (Syn. Oomycetes), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and Deuteromycetes (Syn. Fungi imperfecti) . Some fungicides are systemically active and can be used in plant protection as foliar, seed dressing or soil fungicide. Furthermore, they are suitable for combating fungi, which inter alia infest wood or roots of plant.
  • Bactericides can be used in crop protection for control of Pseudomonadaceae, Rhizobiaceae, Enterobacteriaceae, Corynebacteriaceae and Streptomycetaceae .
  • Non-limiting examples of pathogens of fungal diseases which can be treated in accordance with the invention include: diseases caused by powdery mildew pathogens, for example Blumeria species, for example Blumeria graminis; Podosphaera species, for example Podosphaera leucotricha Sphaerotheca species, for example Sphaerotheca fuliginea; Uncinula species, for example Uncinula necator, diseases caused by rust disease pathogens, for example Gymnosporangium species, for example Gymnosporangium sabinae; Hemileia species, for example Hemileia vastatrix; Phakopsora species, for example Phakopsora pachyrhizi and Phakopsora meibomiae; Puccinia species, for example Puccinia recondite, P.
  • diseases caused by powdery mildew pathogens for example Blumeria species, for example Blumeria graminis
  • Uromyces species for example Uromyces appendiculatus
  • diseases caused by pathogens from the group of the Oomycetes for example Albugo species, for example Algubo Candida
  • Bremia species for example Bremia lacfucae
  • Peronospora species for example Peronospora pisi or P.
  • brassicae Phyfophfhora species, for example Phyfophfhora infesfans; Plasmopara species, for example Plasmopara vificola; Pseudoperonospora species, for example Pseudoperonospora humuli or Pseudoperonospora cubensis; Pyfhium species, for example Pyfhium ulfimum; leaf blotch diseases and leaf wilt diseases caused, for example, by Alfernaria species, for example Alfernaria solani; Cercospora species, for example Cercospora beficola; Cladiosporium species, for example Cladiosporium cucumerinum; Cochliobolus species, for example Cochliobolus safivus (conidia form: Drechslera, Syn: Helminthosporium), Cochliobolus miyabeanus; Collefofrichum species, for example Collef
  • Phaeosphaeria species for example Phaeosphaeria nodorum
  • Pyrenophora species for example Pyrenophora feres, Pyrenophora frifici repenfis
  • Ramularia species for example Ramularia collo-cygni, Ramularia areola
  • Rhynchosporium species for example Rhynchosporium secalis
  • Sepforia species for example Sepforia apii, Sepforia lycopersii
  • Typhula species for example Typhula incarnafa
  • Venfuria species for example Venfuria inaequalis
  • root and stem diseases caused, for example, by Corficium species for example Corficium graminearum
  • Fusarium species for example Fusarium oxysporum
  • Gaeumannomyces species for example Gaeumannomyces graminis
  • Rhizocfonia species such as, for example Rhizo
  • Urocystis species for example Urocystis occulta
  • Ustilago species for example Ustilago nuda, IS. nuda tritici
  • fruit rof caused, for example, by Aspergillus species, for example Aspergillus flavus
  • Botrytis species for example Botrytis cinerea
  • Penicillium species for example Penicillium expansum and P.
  • Sclerotinia species for example Sclerotinia sclerotiorum
  • Verticilium species for example Verticilium alboatrum
  • Aphanomyces species caused for example by Aphanomyces euteiches
  • Ascochyta species caused for example by Ascochyta lentis
  • Aspergillus species caused for example by Aspergillus flavus
  • Cladosporium species caused for example by Cladosporium herbarum
  • Cochliobolus species caused for example by Cochliobolus sativus
  • Drechslera, Bipolaris Syn Helminfhosporium
  • Colletotrichum species caused for example by Colletotrichum coccodes
  • Fusarium species caused for example by Fusarium species, caused for example by Fusarium
  • Taphrina species for example Taphrina deformans
  • decline diseases of wooden plants caused, for example, by Esca disease caused for example by Phaemoniella clamydospora, Phaeoacremonium aleophilum and Fomitiporia mediterranea
  • Eutypa dyeback caused for example by Eutypa lata
  • Ganoderma diseases caused for example by Ganoderma boninense
  • Rigidoporus diseases caused for example by Rigidoporus lignosus
  • diseases of flowers and seeds caused, for example, by Botrytis species, for example Botrytis cinerea
  • diseases of plant tubers caused, for example, by Rhizoctonia species, for example Rhizoctonia solani
  • Helminthosporium species for example Helminthosporium solani
  • Helminthosporium species for example Helminthosporium solani
  • Plasmodiophora species for example Plamodiophora brassicae
  • diseases caused by bacterial pathogens for example Xanthomonas species, for example Xanthomonas campestris pv. oryzae
  • Pseudomonas species for example Pseudomonas syringae pv. lachrymans
  • Erwinia species for example Erwinia amylovora.
  • the following diseases of soya beans can be controlled with preference:
  • Fungal diseases on roots and the stem base caused, for example, by black root rot (Calonecfria crofalariae), charcoal rot (Macrophomina phaseolina), fusarium blight or wilt, root rot, and pod and collar rot (Fusarium oxysporum, Fusarium orfhoceras, Fusarium semifecfum, Fusarium equisefi), mycoleptodiscus root rot (Mycolepfodiscus ferresfris), neocosmospora (Neocosmospora vasinfecfa), pod and stem blight ⁇ Diaporfhe phaseolorum), stem canker (Diaporfhe phaseolorum var.
  • phytophthora rot (Phyfophfhora megasperma), brown stem rot (Phialophora gregafa), pythium rot (Pyfhium aphanidermafum, Pyfhium irregulare, Pyfhium debaryanum, Pyfhium myriofylum, Pyfhium ulfimum), rhizoctonia root rot, stem decay, and damping- off (Rhizocfonia solani), sclerotica stem decay (Sclerofinia sclerofiorum), sclerotica southern blight (Sclerofinia rolfsii), thielaviopsis root rot (Thielaviopsis basicola) .
  • inventive compositions can be used for curative or protective/preventive control of phytopathogenic fungi.
  • the invention therefore also relates to curative and protective methods for controlling phytopathogenic fungi by the use of the inventive composition, which is applied to the seed, the plant or plant parts, the fruit or the soil in which the plants grow.
  • compositions are well tolerated by plants at the concentrations required for controlling plant diseases allows the treatment of above-ground parts of plants, of propagation stock and seeds, and of the soil.
  • all plants and plant parts can be treated.
  • plants are meant all plants and plant populations such as desirable and undesirable wild plants, cultivars and plant varieties (whether or not protectable by plant variety or plant breeder's rights).
  • Cultivars and plant varieties can be plants obtained by conventional propagation and breeding methods which can be assisted or supplemented by one or more biotechnological methods such as by use of double haploids, protoplast fusion, random and directed mutagenesis, molecular or genetic markers or by bioengineering and genetic engineering methods.
  • plant parts are meant all above ground and below ground parts and organs of plants such as shoot, leaf, blossom and root, whereby for example leaves, needles, stems, branches, blossoms, fruiting bodies, fruits and seed as well as roots, corms and rhizomes are listed.
  • Crops and vegetative and generative propagating material for example cuttings, corms, rhizomes, runners and seeds also belong to plant parts.
  • the inventive composition when it is well tolerated by plants, has favourable homeotherm toxicity and is well tolerated by the environment, is suitable for protecting plants and plant organs, for enhancing harvest yields, for improving the quality of the harvested material. It can preferably be used as crop protection composition. It is active against normally sensitive and resistant species and against all or some stages of development.
  • Plants which can be treated in accordance with the invention include the following main crop plants: maize, soya bean, alfalfa, cotton, sunflower, Brassica oil seeds such as Brassica napus (e.g. canola, rapeseed), Brassica rapa, B. juncea (e.g. (field) mustard) and Brassica carinata, Arecaceae sp. (e.g. oilpalm, coconut), rice, wheat, sugar beet, sugar cane, oats, rye, barley, millet and sorghum, triticale, flax, nuts, grapes and vine and various fruit and vegetables from various botanic taxa, e.g. Rosaceae sp. (e.g.
  • pome fruits such as apples and pears, but also stone fruits such as apricots, cherries, almonds, plums and peaches, and berry fruits such as strawberries, raspberries, red and black currant and gooseberry), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp. (e.g. olive tree), Actinidaceae sp., Lauraceae sp. (e.g. avocado, cinnamon, camphor), Musaceae sp. (e.g.
  • Rubiaceae sp. e.g. coffee
  • Theaceae sp. e.g. tea
  • Sterculiceae sp. e.g. lemons, oranges, mandarins and grapefruit
  • Solanaceae sp. e.g. tomatoes, potatoes, peppers, capsicum, aubergines, tobacco
  • Liliaceae sp. Compositae sp. (e.g. lettuce, artichokes and chicory - including root chicory, endive or common chicory), Umbelliferae sp. (e.g.
  • Cucurbitaceae sp. e.g. cucumbers - including gherkins, pumpkins, watermelons, calabashes and melons
  • Alliaceae sp. e.g. leeks and onions
  • Cruciferae sp. e.g. white cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, pak choi, kohlrabi, radishes, horseradish, cress and Chinese cabbage
  • Leguminosae sp. e.g. peanuts, peas, lentils and beans - e.g. common beans and broad beans
  • Chenopodiaceae sp. e.g.
  • the treatment according to the invention may also result in super-additive (“synergistic”) effects.
  • compositions in the treatment according to the invention may also have a strengthening effect in plants.
  • the defense system of the plant against attack by unwanted phytopathogenic fungi and/ or microorganisms and/or viruses is mobilized.
  • Plant-strengthening (resistance-inducing) substances are to be understood as meaning, in the present context, those substances or combinations of substances which are capable of stimulating the defense system of plants in such a way that, when subsequently inoculated with unwanted phytopathogenic fungi and/or microorganisms and/or viruses, the treated plants display a substantial degree of resistance to these phytopathogenic fungi and/or microorganisms and/or viruses,
  • composition according to the present invention in the treatment according ⁇ o the invention plants can be protected against attack by the abovementioned pathogens within a certain period of time after the treatment.
  • the period of time within which protection is effected generally extends from 1 to 10 days, preferably 1 to 7 days, after the treatment of the plants with the active compounds.
  • Plants and plant cultivars which are also preferably to be treated according to the invention are resistant against one or more biotic stresses, i.e. said plants show a better defense against animal and microbial pests, such as against nematodes, insects, mites, phytopathogenic fungi, bacteria, viruses and/or viroids.
  • Plants and plant cultivars which may also be treated according to the invention are those plants which are resistant to one or more abiotic stresses, i. e. that already exhibit an increased plant health with respect to stress tolerance.
  • Abiotic stress conditions may include, for example, drought, cold temperature exposure, heat exposure, osmotic stress, flooding, increased soil salinity, increased mineral exposure, ozon exposure, high light exposure, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients, shade avoidance.
  • the treatment of these plants and cultivars with the composition of the present invention additionally increases the overall plant health (cf. above).
  • Plants and plant cultivars which may also be treated according to the invention are those plants characterized by enhanced yield characteristics, i. e. that already exhibit an increased plant health with respect to this feature. Increased yield in said plants can be the result of, for example, improved plant physiology, growth and development, such as water use efficiency, water retention efficiency, improved nitrogen use, enhanced carbon assimilation, improved photosynthesis, increased germination efficiency and accelerated maturation.
  • Yield can furthermore be affected by improved plant architecture (under stress and non-stress conditions), including but not limited to, early flowering, flowering control for hybrid seed production, seedling vigor, plant size, internode number and distance, root growth, seed size, fruit size, pod size, pod or ear number, seed number per pod or ear, seed mass, enhanced seed filling, reduced seed dispersal, reduced pod dehiscence and lodging resistance.
  • Further yield traits include seed composition, such as carbohydrate content, protein content, oil content and composition, nutritional value, reduction in anti-nutritional compounds, improved processability and better storage stability.
  • the treatment of these plants and cultivars with the composition of the present invention additionally increases the overall plant health (cf. above).
  • Plants that may be treated according to the invention are hybrid plants that already express the characteristic of heterosis or hybrid vigor which results in generally higher yield, vigor, health and resistance towards biotic and abiotic stress factors. Such plants are typically made by crossing an inbred male-sterile parent line (the female parent) with another inbred male-fertile parent line (the male parent). Hybrid seed is typically harvested from the male sterile plants and sold to growers. Male sterile plants can sometimes (e.g. in corn) be produced by detasseling, i.e. the mechanical removal of the male reproductive organs (or males flowers) but, more typically, male sterility is the result of genetic determinants in the plant genome.
  • male sterile plants can also be obtained by plant biotechnology methods such as genetic engineering.
  • a particularly useful means of obtaining male-sterile plants is described in WO 89/10396 in which, for example, a ribonuclease such as barnase is selectively expressed in the tapetum cells in the stamens. Fertility can then be restored by expression in the tapetum cells of a ribonuclease inhibitor such as barstar.
  • Plants or plant cultivars obtained by plant biotechnology methods such as genetic engineering) which may be treated according to the invention are herbicide-tolerant plants, i.e. plants made tolerant to one or more given herbicides. Such plants can be obtained either by genetic transformation, or by selection of plants containing a mutation imparting such herbicide tolerance.
  • Herbicide-tolerant plants are for example glyphosate-tolerant plants, i.e. plants made tolerant to the herbicide glyphosate or salts thereof. Plants can be made tolerant to glyphosate through different means. For example, glyphosate-tolerant plants can be obtained by transforming the plant with a gene encoding the enzyme 5- enolpyruvylshikima ⁇ e-3-phospha ⁇ e synthase (EPSPS) .
  • EPSPS 5- enolpyruvylshikima ⁇ e-3-phospha ⁇ e synthase
  • EPSPS genes are the AroA gene (mutant CT7) of the bacterium Salmonella typhimurium, the CP4 gene of the bacterium Agrobacterium sp, the genes encoding a Petunia EPSPS, a Tomato EPSPS, or an Eleusine EPSPS. It can also be a mutated EPSPS.
  • Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes a glyphosate oxido- reductase enzyme.
  • Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes a glyphosate acetyl transferase enzyme.
  • Glyphosate-tolerant plants can also be obtained by selecting plants containing naturally-occurring mutations of the above-mentioned genes.
  • Other herbicide resistant plants are for example plants that are made tolerant to herbicides inhibiting the enzyme glutamine synthase, such as bialaphos, phosphinothricin or glufosinate.
  • Such plants can be obtained by expressing an enzyme detoxifying the herbicide or a mutant glutamine synthase enzyme that is resistant to inhibition.
  • One such efficient detoxifying enzyme is an enzyme encoding a phosphinothricin acetyltransferase (such as the bar or pat protein from Streptomyces species) . Plants expressing an exogenous phosphinothricin acetyltransferase are also described.
  • hydroxyphenylpyruvatedioxygenase HPPD
  • hydroxyphenylpyruvatedioxygenases are enzymes that catalyze the reaction in which para-hydroxyphenylpyruvate (HPP) is transformed into homogentisate.
  • Plants tolerant to HPPD-inhibitors can be transformed with a gene encoding a naturally-occurring resistant HPPD enzyme, or a gene encoding a mutated HPPD enzyme.
  • Tolerance to HPPD-inhibitors can also be obtained by transforming plants with genes encoding certain enzymes enabling the formation of homogentisate despite the inhibition of the native HPPD enzyme by the HPPD-inhibitor. Tolerance of plants to HPPD inhibitors can also be improved by transforming plants with a gene encoding an enzyme prephenate dehydrogenase in addition to a gene encoding an HPPD-tolerant enzyme. Still further herbicide resistant plants are plants that are made tolerant to acetolactate synthase (ALS) inhibitors.
  • ALS acetolactate synthase
  • Known ALS-inhibitors include, for example, sulfonylurea, imidazolinone, triazolopyrimidines, pyrimidinyoxy( ⁇ hio) benzoa ⁇ es, and/or sulfonylaminocarbonyltriazolinone herbicides.
  • Different mutations in the ALS enzyme also known as acetohydroxyacid synthase, AHAS
  • AHAS acetohydroxyacid synthase
  • the production of sulfonylurea-tolerant plants and imidazolinone-tolerant plants is described in WO 1996/033270. Other imidazolinone-tolerant plants are also described. Further sulfonylurea- and imidazolinone-tolerant plants are also described in for example WO 2007/024782.
  • plants tolerant to imidazolinone and/or sulfonylurea can be obtained by induced mutagenesis, selection in cell cultures in the presence of the herbicide or mutation breeding as described for example for soybeans, for rice, for sugar beet, for lettuce, or for sunflower.
  • Plants or plant cultivars obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are insect- resistant transgenic plants, i.e. plants made resistant to attack by certain target insects. Such plants can be obtained by genetic transformation, or by selection of plants containing a mutation imparting such insect resistance.
  • An "insect-resistant transgenic plant”, as used herein, includes any plant containing at least one transgene comprising a coding sequence encoding:
  • insecticidal crystal protein from Bacillus thuringiensis or an insecticidal portion thereof, such as the insecticidal crystal proteins listed online at:
  • a crystal protein from Bacillus thuringiensis or a portion thereof which is insecticidal in the presence of a second other crystal protein from Bacillus thuringiensis or a portion thereof, such as the binary toxin made up of the Cry34 and Cry35 crystal proteins; or
  • a hybrid insecticidal protein comprising parts of different insecticidal crystal proteins from Bacillus thuringiensis, such as a hybrid of the proteins of 1 ) above or a hybrid of the proteins of 2) above, e.g., the Cry 1 A.105 protein produced by corn event MON98034 (WO 2007/027777); or
  • VIP vegetative insecticidal
  • secreted protein from Bacillus thuringiensis or Bacillus cereus which is insecticidal in the presence of a second secreted protein from Bacillus thuringiensis or B. cereus, such as the binary toxin made up of the VIP 1 A and
  • hybrid insecticidal protein comprising parts from different secreted proteins from Bacillus thuringiensis or Bacillus cereus, such as a hybrid of the proteins in 1 ) above or a hybrid of the proteins in 2) above; or
  • an insect-resistant transgenic plant also includes any plant comprising a combination of genes encoding the proteins of any one of the above classes 1 to 8.
  • an insect-resistant plant contains more than one transgene encoding a protein of any one of the above classes 1 to 8, to expand the range of target insect species affected when using different proteins directed at different target insect species, or to delay insect resistance development to the plants by using different proteins insecticidal to the same target insect species but having a different mode of action, such as binding to different receptor binding sites in the insect.
  • Plants or plant cultivars obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are tolerant to abiotic stresses.
  • Such plants can be obtained by genetic transformation, or by selection of plants containing a mutation imparting such stress resistance.
  • Particularly useful stress tolerance plants include: ⁇ . plants which contain a transgene capable of reducing the expression and/or the activity of poly(ADP-ribose) polymerase (PARP) gene in the plant cells or plants
  • plants which contain a stress tolerance enhancing transgene capable of reducing the expression and/or the activity of the poly(ADP- ribose)glycohydrolase (PARG) encoding genes of the plants or plants cells.
  • PARG poly(ADP- ribose)glycohydrolase
  • plants which contain a stress tolerance enhancing transgene coding for a plant-functional enzyme of the nicotinamide adenine dinucleotide salvage synthesis pathway including nicotinamidase, nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide adenyl transferase, nicotinamide adenine dinucleotide synthetase or nicotine amide phosphorybosyltransferase.
  • nicotinamidase nicotinate phosphoribosyltransferase
  • nicotinic acid mononucleotide adenyl transferase nicotinamide adenine dinucleotide synthetase or nicotine amide phosphorybosyltransferase.
  • Plants or plant cultivars obtained by plant biotechnology methods such as genetic engineering which may also be treated according to the invention show altered quantity, quality and/or storage-stability of the harvested product and/or altered properties of specific ingredients of the harvested product such as :
  • transgenic plants which synthesize a modified starch, which in its physical- chemical characteristics, in particular the amylose content or the amylose/amylopectin ratio, the degree of branching, the average chain length, the side chain distribution, the viscosity behaviour, the gelling strength, the starch grain size and/or the starch grain morphology, is changed in comparison with the synthesised starch in wild type plant cells or plants, so that this is better suited for special applications.
  • a modified starch which in its physical- chemical characteristics, in particular the amylose content or the amylose/amylopectin ratio, the degree of branching, the average chain length, the side chain distribution, the viscosity behaviour, the gelling strength, the starch grain size and/or the starch grain morphology, is changed in comparison with the synthesised starch in wild type plant cells or plants, so that this is better suited for special applications.
  • transgenic plants which synthesize non starch carbohydrate polymers or which synthesize non starch carbohydrate polymers with altered properties in comparison to wild type plants without genetic modification.
  • Examples are plants producing polyfructose, especially of the inulin and levan-type, plants producing alpha 1 ,4 glucans, plants producing alpha-1 ,6 branched alpha- 1 ,4-glucans, plants producing alternan,
  • Plants or plant cultivars which may also be treated according to the invention are plants, such as cotton plants, with altered fiber characteristics.
  • Such plants can be obtained by genetic transformation or by selection of plants contain a mutation imparting such altered fiber characteristics and include: a) Plants, such as cotton plants, containing an altered form of cellulose synthase genes,
  • Plants such as cotton plants, having fibers with altered reactivity, e.g. through the expression of N-ac ⁇ eylglucosamine ⁇ ransferase gene including nodC and chitinsynthase genes.
  • Plants or plant cultivars which may also be treated according to the invention are plants, such as oilseed rape or related Brassica plants, with altered oil profile characteristics.
  • Such plants can be obtained by genetic transformation or by selection of plants contain a mutation imparting such altered oil characteristics and include: a) Plants, such as oilseed rape plants, producing oil having a high oleic acid content,
  • transgenic plants which may be treated according to the invention are plants which comprise one or more genes which encode one or more toxins, such as the following which are sold under the trade names YIELD GARD ® (for example maize, cotton, soya beans), nockOut ® (for example maize), BiteGard ® (for example maize), B ⁇ -X ⁇ ra ® (for example maize), StarLink ® (for example maize), Bollgard ® (cotton), Nucotn ® (cotton), Nucotn 33B ® (cotton), NatureGard ® (for example maize), Protecta® and NewLeaf ® (potato).
  • YIELD GARD ® for example maize, cotton, soya beans
  • nockOut ® for example maize
  • BiteGard ® for example maize
  • B ⁇ -X ⁇ ra ® for example maize
  • StarLink ® for example maize
  • Bollgard ® cotton
  • Nucotn ® cotton
  • herbicide-tolerant plants examples include maize varieties, cotton varieties and soya bean varieties which are sold under the trade names Roundup Ready ® (tolerance to glyphosate, for example maize, cotton, soya bean), Liberty Link ® (tolerance to phosphinotricin, for example oilseed rape), IMI ® (tolerance to imidazolinones) and STS ® (tolerance to sulphonylureas, for example maize).
  • Herbicide-resistant plants plants bred in a conventional manner for herbicide tolerance
  • Clearfield ® for example maize.
  • Particularly useful transgenic plants which may be treated according to the invention are plants containing transformation events, or a combination of transformation events, and that are listed for example in the databases for various national or regional regulatory agencies including Event 1 143-14A (cotton, insect control, not deposited, described in WO 06/128569); Event 1 143-51 B (cotton, insect control, not deposited, described in WO 06/128570); Event 1445 (cotton, herbicide tolerance, not deposited, described in US-A 2002-120964 or WO 02/034946); Event 17053 (rice, herbicide tolerance, deposited as PTA-9843, described in WO 10/1 1 7737); Event 17314 (rice, herbicide tolerance, deposited as PTA-9844, described in WO 10/1 17735); Event 281 -24-236 (cotton, insect control - herbicide tolerance, deposited as PTA-6233, described in WO 05/103266 or US-A 2005-216969); Event 3006-210-23 (cotton, insect control - herbicide tolerance,
  • Event CE43-67B (cotton, insect control, deposited as DSM ACC2724, described in US-A 2009-21 7423 or WO 06/128573); Event CE44-69D (cotton, insect control, not deposited, described in US-A 2010-0024077); Event CE44-69D (cotton, insect control, not deposited, described in WO 06/128571 ); Event CE46-02A (cotton, insect control, not deposited, described in WO 06/128572); Event COT102 (cotton, insect control, not deposited, described in US-A 2006-130175 or WO 04/039986); Event COT202 (cotton, insect control, not deposited, described in US-A 2007-067868 or WO 05/054479); Event COT203 (cotton, insect control, not deposited, described in WO 05/054480); Event DAS40278 (corn, herbicide tolerance, deposited as ATCC PTA-10244, described in
  • transgenic plants which may be treated according to the invention are plants containing transformation events, or combination of transformation events, that are listed for example in the databases from various national or regional regulatory agencies (see for example http://gmoinfo.jrc.it/gmp_browse.aspx and http://www.agbios.com/dbase.php).
  • the present invention relates to a method of controlling nematodes or insects in the soil surrounding a plant comprising applying an effective amount of the composition according to the invention to said soil.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Biotechnology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La présente invention concerne une composition comprenant au moins un agent de lutte biologique choisi dans le groupe consistant en la souche 251 de Paecilomyces lilacinus (AGAL No. 89/030550) et Coniothyrium minitans CON/M/91-08 (DSM 9660) et/ou un mutant de ces souches ayant toutes les caractéristiques d'identification de la souche respective, et/ou au moins un métabolite produit par la souche respective qui présente une activité contre les nématodes, les insectes et/ou les phytopathogènes, et au moins un agent (II) de lutte biologique supplémentaire qui est choisi dans le groupe consistant en protozoaires, virus, nématodes entomopathogènes et inoculants dans une quantité synergiquement efficace. En outre, la présente invention concerne une trousse de pièces comprenant ladite composition et l'utilisation de ladite composition.
PCT/EP2013/075326 2012-12-03 2013-12-03 Composition comprenant des agents de lutte biologique WO2014086753A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12195201.4 2012-12-03
EP12195201 2012-12-03

Publications (2)

Publication Number Publication Date
WO2014086753A2 true WO2014086753A2 (fr) 2014-06-12
WO2014086753A3 WO2014086753A3 (fr) 2014-08-14

Family

ID=47257694

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2013/075326 WO2014086753A2 (fr) 2012-12-03 2013-12-03 Composition comprenant des agents de lutte biologique

Country Status (1)

Country Link
WO (1) WO2014086753A2 (fr)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2962567A1 (fr) * 2014-07-01 2016-01-06 Basf Se Mélanges ternaires comprenant des biopesticides et au moins deux insecticides chimiques
CN110117545A (zh) * 2018-02-07 2019-08-13 南京农业大学 一种具有Cr(VI)耐性及还原能力的外生菌根真菌及其应用
CN111557309A (zh) * 2019-01-25 2020-08-21 河南勇冠乔迪农业科技有限公司 一种棉铃虫核型多角体病毒悬浮剂
US11747316B2 (en) 2014-06-26 2023-09-05 Ait Austrian Institute Of Technology Gmbh Plant-endophyte combinations and uses therefor
US11754553B2 (en) 2013-09-04 2023-09-12 Indigo Ag, Inc. Agricultural endophyte-plant compositions, and methods of use
US11753618B2 (en) 2013-12-24 2023-09-12 Indigo Ag, Inc. Method for propagating microorganisms within plant bioreactors and stably storing microorganisms within agricultural seeds
US11751515B2 (en) 2015-12-21 2023-09-12 Indigo Ag, Inc. Endophyte compositions and methods for improvement of plant traits in plants of agronomic importance
US11751571B2 (en) 2015-05-01 2023-09-12 Indigo Ag, Inc. Isolated complex endophyte compositions and methods for improved plant traits
US11766045B2 (en) 2016-12-01 2023-09-26 Indigo Ag, Inc. Modulated nutritional quality traits in seeds
US11771090B2 (en) 2013-11-06 2023-10-03 The Texas A&M Unversity System Fungal endophytes for improved crop yields and protection from pests
US11793202B2 (en) 2013-06-26 2023-10-24 Indigo Ag, Inc. Methods of use of seed-origin endophyte populations
US11807586B2 (en) 2016-12-23 2023-11-07 The Texas A&M University System Fungal endophytes for improved crop yields and protection from pests
US11819027B2 (en) 2015-06-08 2023-11-21 Indigo Ag, Inc. Streptomyces endophyte compositions and methods for improved agronomic traits in plants
US11882838B2 (en) 2017-04-27 2024-01-30 The Flinders University Of South Australia Bacterial inoculants
US11985931B2 (en) 2017-03-01 2024-05-21 Indigo Ag, Inc. Endophyte compositions and the methods for improvement of plant traits

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105441485B (zh) * 2015-11-23 2019-12-17 鲁东大学 一种叶用和根施农业生防制剂同时制备的方法及其应用

Citations (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4245432A (en) 1979-07-25 1981-01-20 Eastman Kodak Company Seed coatings
US4272417A (en) 1979-05-22 1981-06-09 Cargill, Incorporated Stable protective seed coating
US4808430A (en) 1987-02-27 1989-02-28 Yazaki Corporation Method of applying gel coating to plant seeds
WO1989010396A1 (fr) 1988-04-28 1989-11-02 Plant Genetic Systems N.V. Plantes avec cellules d'etamines modifiees
WO1991002051A1 (fr) 1989-08-03 1991-02-21 The Australian Technological Innovation Corporation Myconematicides
EP0539588A1 (fr) 1990-07-05 1993-05-05 Nippon Soda Co., Ltd. Derive d'amine
WO1996021358A1 (fr) 1995-01-14 1996-07-18 Prophyta Biologischer Pflanzenschutz Gmbh Isolat de champignon, preparation pour lutter contre les champignons pathogenes des plantes, ses procedes de preparation et son utilisation
WO1996033270A1 (fr) 1995-04-20 1996-10-24 American Cyanamid Company Produits resistant a des herbicides elabores a partir de structures
WO1998044140A1 (fr) 1997-04-03 1998-10-08 Dekalb Genetics Corporation Lignees de mais resistantes aux glyphosates
US5876739A (en) 1996-06-13 1999-03-02 Novartis Ag Insecticidal seed coating
WO2000026356A1 (fr) 1998-11-03 2000-05-11 Aventis Cropscience N. V. Riz tolerant au glufosinate
WO2000026345A1 (fr) 1998-11-03 2000-05-11 Aventis Cropscience N.V. Riz tolerant au glufosinate
WO2001031042A2 (fr) 1999-10-29 2001-05-03 Aventis Cropscience N.V. Plantes brassica male sterile et procedes de production de ces plantes
WO2001041558A1 (fr) 1999-12-08 2001-06-14 Aventis Cropscience N.V. Colza oleagineux d'hiver hybrides et son procede de production
WO2001051654A2 (fr) 2000-01-11 2001-07-19 Bayer Cropscience N.V. Procedes et assortiments de materiel permettant d'identifier l'evenement elite gat-zm1 dans les echantillons biologiques
WO2002028186A2 (fr) 2000-10-06 2002-04-11 Monsanto Technology, Llc Traitement de semences avec des melanges d'insecticides
WO2002034946A2 (fr) 2000-10-25 2002-05-02 Monsanto Technology Llc Mecanisme biochimique de plant de coton pv-ghgt07(1445), compositions et techniques de detection de celui-ci
WO2002036831A2 (fr) 2000-10-30 2002-05-10 Monsanto Technology Llc Colza canola pv-bngt(rt73), compositions et procedes de detection correspondants
WO2002044407A2 (fr) 2000-11-30 2002-06-06 Ses Europe N.V. Séquence des flancs de t227-1
US20020102582A1 (en) 2000-09-13 2002-08-01 Levine Elaine B. Corn event MON810 and compositions and methods for detection thereof
WO2002080675A1 (fr) 2001-03-21 2002-10-17 Monsanto Technology, Llc Procede permettant de commander la liberation de principes actifs agricoles de semences traitees de plantes
WO2002096882A1 (fr) 2001-05-31 2002-12-05 Nihon Nohyaku Co., Ltd. Derives d'anilide substitues, produits intermediaires de ces derives, produits chimiques agricoles et horticoles et leur utilisation
WO2002100163A2 (fr) 2001-06-11 2002-12-19 Monsanto Technology Llc Evenement mon15985 du coton et compositions et procedes servant a sa detection
WO2003013224A2 (fr) 2001-08-06 2003-02-20 Bayer Bioscience N.V. Cotonniers avec tolerance aux herbicides et procedes de production et d'identification de ces cotonniers
WO2003052073A2 (fr) 2001-12-17 2003-06-26 Syngenta Participations Ag Nouvel evenement du mais
US20030126634A1 (en) 1990-08-09 2003-07-03 Dekalb Genetics Corporation Methods and compositions for the increase of yield in plants
US20030176428A1 (en) 1998-11-16 2003-09-18 Schneidersmann Ferdinand Martin Pesticidal composition for seed treatment
WO2003106457A1 (fr) 2002-06-14 2003-12-24 Syngenta Limited Derives de spiroindolinepiperidine
WO2004011601A2 (fr) 2002-07-29 2004-02-05 Monsanto Technology, Llc Mais pv-zmir13 designe mon863, composition et procedes de detection
WO2004039986A1 (fr) 2002-10-29 2004-05-13 Syngenta Participations Ag Coton insecticide cot102
WO2004053062A2 (fr) 2002-12-05 2004-06-24 Monsanto Technology Llc Evenement associe a l'agrostide asr-368 et compositions et procedes de detection de la presence de celle-ci
WO2004072235A2 (fr) 2003-02-12 2004-08-26 Monsanto Technology Llc Evenement mon 88913 de plant de coton et procedes de detection correspondants
WO2004074492A1 (fr) 2003-02-20 2004-09-02 Kws Saat Ag Betteraves sucrieres tolerant le glyphosate
US20040172669A1 (en) 2003-02-28 2004-09-02 Josef Kraus Glyphosate tolerant sugar beet
WO2004099160A1 (fr) 2003-05-12 2004-11-18 Sumitomo Chemical Company, Limited Composes de pyrimidine et compostion de lutte contre les animaux nuisibles contenant ces composes
WO2004099447A2 (fr) 2003-05-02 2004-11-18 Dow Agrosciences Llc Mais tc1507 et procedes de detection de celui-ci
WO2005035486A1 (fr) 2003-10-02 2005-04-21 Basf Aktiengesellschaft 2-cyanobenzenesulfonamides destines a lutter contre les animaux nuisibles
WO2005054479A1 (fr) 2003-12-01 2005-06-16 Syngenta Participations Ag Cotonnier resistant aux insectes et procedes pour detecter celui-ci
WO2005054480A2 (fr) 2003-12-01 2005-06-16 Syngenta Participations Ag Plants de coton resistant aux insectes et procedes de detection de ces derniers
WO2005059103A2 (fr) 2003-12-15 2005-06-30 Monsanto Technology Llc Plant de mais mon88017, compositions et procedes de detection associes
WO2005061720A2 (fr) 2003-12-11 2005-07-07 Monsanto Technology Llc Compositions de mais a haute teneur en lysine et methodes de detection correspondantes
WO2005063094A1 (fr) 2003-12-23 2005-07-14 Koninklijke Philips Electronics N.V. Appareil de preparation de boissons comportant plusieurs chambres de reception de boissons
WO2005077934A1 (fr) 2004-02-18 2005-08-25 Ishihara Sangyo Kaisha, Ltd. Anthranilamides, procédé pour la production de ceux-ci et agents antiparasitaires contenant ceux-ci
WO2005085216A1 (fr) 2004-03-05 2005-09-15 Nissan Chemical Industries, Ltd. Composé benzamide substitué par de l’isoxazoline et agent de contrôle d’organisme nocif
US20050216969A1 (en) 2004-03-26 2005-09-29 Dow Agrosciences Llc Cry1F and Cry1AC transgenic cotton lines and event-specific identification thereof
WO2005103301A2 (fr) 2004-03-25 2005-11-03 Syngenta Participations Ag Mais mir604
US20060070139A1 (en) 2004-09-29 2006-03-30 Pioneer Hi-Bred International, Inc. Corn event DAS-59122-7 and methods for detection thereof
WO2006043635A1 (fr) 2004-10-20 2006-04-27 Kumiai Chemical Industry Co., Ltd. Dérivé de 3-triazolylphénylsulfide et insecticide/acaricide/nématicide incluant ledit dérivé au titre de principe actif
WO2006056433A2 (fr) 2004-11-26 2006-06-01 Basf Aktiengesellschaft Composes de 2-cyano-3-(halo)alcoxy-benzenesulfonamide destines au combat des parasites des animaux
WO2006089633A2 (fr) 2005-02-22 2006-08-31 Bayer Cropscience Ag Cetoenols cycliques substitues par spirocetal
WO2006098952A2 (fr) 2005-03-16 2006-09-21 Syngenta Participations Ag Mais 3272 et procedes pour le detecter
WO2006100288A2 (fr) 2005-03-24 2006-09-28 Basf Aktiengesellschaft Composes a base de 2-cyanobenzenesulfonamide, destines au traitement des semences
WO2006108675A2 (fr) 2005-04-11 2006-10-19 Bayer Bioscience N.V. Evenement elite a5547-127 et procedes et trousses pour l'identification d'un tel evenement dans des echantillons biologiques
WO2006108674A2 (fr) 2005-04-08 2006-10-19 Bayer Bioscience N.V. Evenement elite a2704-12 et procedes et trousses permettant d'identifier cet evenement dans des prelevements biologiques
WO2006128572A1 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce46-02a
WO2006130436A2 (fr) 2005-05-27 2006-12-07 Monsanto Technology Llc Evenement de soja mon89788 et procedes de detection de celui-ci
WO2006128569A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide 1143-14a
WO2006128571A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce44-69d
WO2006128568A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide t342-142
WO2006128573A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce43-67b
WO2006128570A1 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide 1143-51b
WO2007017186A1 (fr) 2005-08-08 2007-02-15 Bayer Bioscience N.V. Cotonniers tolerants aux herbicides et leurs procedes d'identification
WO2007024782A2 (fr) 2005-08-24 2007-03-01 Pioneer Hi-Bred International, Inc. Compositions assurant une tolerance a de multiples herbicides et methodes d'utilisation
WO2007027777A2 (fr) 2005-08-31 2007-03-08 Monsanto Technology Llc Sequences nucleotidiques codant des proteines insecticides
WO2007040280A1 (fr) 2005-10-06 2007-04-12 Nippon Soda Co., Ltd. Cyclic amine compound and pest control agent
WO2007057407A2 (fr) 2005-11-21 2007-05-24 Basf Se Procedes insecticides utilisant des derives de 3-amino-1,2-benzisothiazole
WO2007075459A2 (fr) 2005-12-16 2007-07-05 E. I. Du Pont De Nemours And Company 5-arylisoxazolines pour lutter contre des parasites invertebres
WO2007091277A2 (fr) 2006-02-10 2007-08-16 Maharashtra Hybrid Seeds Company Limited (Mahyco) Aubergine transgenique (solanum melongena) comprenant un evenement ee-i
WO2007101369A1 (fr) 2006-03-09 2007-09-13 East China University Of Science And Technology Méthode de préparation et utilisation de composés présentant une action biocide
WO2007115643A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués
WO2007115646A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués utilisés comme insecticides
WO2007115644A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués
WO2007140256A1 (fr) 2006-05-26 2007-12-06 Monsanto Technology, Llc Plant et semence de maïs correspondant au produit transgénique mon89034, procédés de détection et utilisation associés
WO2007142840A2 (fr) 2006-06-03 2007-12-13 Syngenta Participations Ag Événement de transformation de maïs mir162
US20070292854A1 (en) 2000-06-22 2007-12-20 Behr Carl F Corn event PV-ZMGT32(nk603) and compositions and methods for detection thereof
WO2007149134A1 (fr) 2006-06-23 2007-12-27 Dow Agrosciences Llc Procédé pour lutter contre des insectes résistant aux insecticides courants
WO2008002872A2 (fr) 2006-06-28 2008-01-03 Pioneer Hi-Bred International, Inc. Événement de soja 3560.4.3.5 et compositions et procedes d'identification et/ou de détection de celui-ci
WO2008009360A2 (fr) 2006-07-20 2008-01-24 Bayer Cropscience Ag Dérivés de n'-cyano-n-halogènalkyle-imidamide
US20080064032A1 (en) 2006-09-13 2008-03-13 Syngenta Participations Ag Polynucleotides and uses thereof
WO2008054747A2 (fr) 2006-10-31 2008-05-08 E. I. Du Pont De Nemours And Company Événement de soja dp-305423-1, leurs compositions et leurs procédés d'identification et/ou de détection
WO2008066153A1 (fr) 2006-11-30 2008-06-05 Meiji Seika Kaisha, Ltd. Agent antiparasitaire
WO2008067911A1 (fr) 2006-12-04 2008-06-12 Bayer Cropscience Ag Cétoénols spirocycliques substitués par le biphényle
WO2008104503A1 (fr) 2007-03-01 2008-09-04 Basf Se Mélanges actifs pesticides comprenant des composés aminothiazoline
WO2008112019A2 (fr) 2006-10-30 2008-09-18 Pioneer Hi-Bred International, Inc. Evènement dp-098140-6 du maïs et compositions et procédés pour son identification et/ou sa détection
WO2008114282A2 (fr) 2007-03-19 2008-09-25 Maharashtra Hybrid Seeds Company Limited Riz transgénique (oryza sativa) comprenant l'événement pe-7 et son procédé de détection
WO2008122406A1 (fr) 2007-04-05 2008-10-16 Bayer Bioscience N.V. Plants de coton résistant aux insectes et leurs procédés d'identification
US20080289060A1 (en) 2006-08-24 2008-11-20 Bayer Bioscience N.V. Herbicide tolerant rice plants and methods for identifying same
WO2008151780A1 (fr) 2007-06-11 2008-12-18 Bayer Bioscience N.V. Cotonniers résistant aux insectes comprenant un événement élite ee-gh6 et leurs procédés d'identification
WO2009049851A1 (fr) 2007-10-15 2009-04-23 Syngenta Participations Ag Dérivés pyrrolidine dione spirohétérocycliques utiles comme pesticides
US20090130071A1 (en) 2007-11-15 2009-05-21 Ai-Guo Gao Soybean Plant And Seed Corresponding To Transgenic Event MON87701 And Methods For Detection Thereof
US20090137395A1 (en) 2006-10-30 2009-05-28 Pioneer Hi-Bred International, Inc. Maize event DP-098140-6 and compositions and methods for the identification and/or detection thereof
WO2009100188A2 (fr) 2008-02-08 2009-08-13 Dow Agrosciences Llc Procédés de détection de l’événement de maïs das-59132
WO2009103049A2 (fr) 2008-02-14 2009-08-20 Pioneer Hi-Bred International, Inc. Evénement spt flanquant l'adn génomique végétal et procédés d'identification de l'événement spt
WO2009102873A1 (fr) 2008-02-15 2009-08-20 Monsanto Technology Llc Plante de soja et graine correspondant à l’évènement transgénique mon87769 et leurs procédés de détection
WO2009111263A1 (fr) 2008-02-29 2009-09-11 Monsanto Technology Llc Plant de maïs correspondant au produit transgénique mon87460 et compositions et procédés de détection associés
WO2009116106A1 (fr) 2008-03-21 2009-09-24 Trentino Sviluppo S.P.A. Trichoderma atroviride sc1 pour la lutte biologique contre les maladies fongiques des végétaux
WO2010005692A2 (fr) 2008-06-16 2010-01-14 E. I. Du Pont De Nemours And Company Carbonyl-amidines cycliques insecticides
WO2010006713A2 (fr) 2008-07-17 2010-01-21 Bayer Cropscience Ag Composés hétérocycliques utilisés comme pesticides
JP2010018586A (ja) 2008-07-14 2010-01-28 Meiji Seika Kaisha Ltd Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤
WO2010024976A1 (fr) 2008-08-29 2010-03-04 Monsanto Technology Llc Plante et semences de soja correspondant à l’événement transgénique mon87754 et procédés pour détection de celui-ci
US20100080887A1 (en) 2008-09-29 2010-04-01 Monsanto Technology Llc Soybean Transgenic Event MON87705 and Methods for Detection Thereof
WO2010069502A2 (fr) 2008-12-18 2010-06-24 Bayer Cropscience Ag Amides d'acide anthranilique substitués par tétrazol, utilisés comme pesticides
WO2010074751A1 (fr) 2008-12-26 2010-07-01 Dow Agrosciences, Llc Compositions insecticides stables renfermant de la sulfoximine
WO2010074747A1 (fr) 2008-12-26 2010-07-01 Dow Agrosciences, Llc Compositions d'insecticide stables et procédés de production associés
WO2010076212A1 (fr) 2008-12-19 2010-07-08 Syngenta Participations Ag Événement de betterave sucrière transgénique gm rz13
WO2010077816A1 (fr) 2008-12-16 2010-07-08 Syngenta Participations Ag Evénement transgénique du maïs 5307
WO2010080829A1 (fr) 2009-01-07 2010-07-15 Basf Agrochemical Products B.V. Évènement de soja 127 et procédés apparentés
WO2010117735A1 (fr) 2009-03-30 2010-10-14 Monsanto Technology Llc Évènement 17314 de riz transgénique et ses procédés d'utilisation
WO2010117737A1 (fr) 2009-03-30 2010-10-14 Monsanto Technology Llc Evénement de riz transgénique 17053 et ses procédés d'utilisation
WO2011022469A2 (fr) 2009-08-19 2011-02-24 Dow Agrosciences Llc Événement das-40278-9 d'aad-1, lignées transgéniques de maïs connexes et identification spécifique d'événement de celui-ci
WO2011034704A1 (fr) 2009-09-17 2011-03-24 Monsanto Technology Llc Variété transgénique mon 87708 du soja et ses méthodes d'utilisation
WO2011049233A1 (fr) 2009-10-23 2011-04-28 Sumitomo Chemical Company, Limited Composition de lutte contre des animaux nuisibles
CN102057925A (zh) 2011-01-21 2011-05-18 陕西上格之路生物科学有限公司 一种含噻虫酰胺和生物源类杀虫剂的杀虫组合物
WO2011062904A1 (fr) 2009-11-23 2011-05-26 Monsanto Technology Llc Événement du maïs transgénique mon 87427 et échelle de développement relative
WO2011066384A1 (fr) 2009-11-24 2011-06-03 Dow Agrosciences Llc Événement 416 de la transformation aad-12, lignées de soja transgéniques associées, et leur identification spécifique à l'événement
WO2011066360A1 (fr) 2009-11-24 2011-06-03 Dow Agrosciences Llc Détection de l'événement 416 du soja aad-12
WO2011075595A1 (fr) 2009-12-17 2011-06-23 Pioneer Hi-Bred International, Inc. Maïs dp-043a47-3 et procédés de détection associés
WO2011075593A1 (fr) 2009-12-17 2011-06-23 Pioneer Hi-Bred International, Inc. Maïs dp-040416-8 et procédés de détection associés
WO2011084621A1 (fr) 2009-12-17 2011-07-14 Pioneer Hi-Bred International, Inc. Evénement de transformation dp-004114-3 du maïs et son procédé de détection
WO2011084632A1 (fr) 2009-12-17 2011-07-14 Pioneer Hi-Bred International, Inc. Evénement de maïs dp-032316-8 et ses procédés de détection

Patent Citations (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272417A (en) 1979-05-22 1981-06-09 Cargill, Incorporated Stable protective seed coating
US4245432A (en) 1979-07-25 1981-01-20 Eastman Kodak Company Seed coatings
US4808430A (en) 1987-02-27 1989-02-28 Yazaki Corporation Method of applying gel coating to plant seeds
WO1989010396A1 (fr) 1988-04-28 1989-11-02 Plant Genetic Systems N.V. Plantes avec cellules d'etamines modifiees
WO1991002051A1 (fr) 1989-08-03 1991-02-21 The Australian Technological Innovation Corporation Myconematicides
EP0539588A1 (fr) 1990-07-05 1993-05-05 Nippon Soda Co., Ltd. Derive d'amine
US20030126634A1 (en) 1990-08-09 2003-07-03 Dekalb Genetics Corporation Methods and compositions for the increase of yield in plants
WO1996021358A1 (fr) 1995-01-14 1996-07-18 Prophyta Biologischer Pflanzenschutz Gmbh Isolat de champignon, preparation pour lutter contre les champignons pathogenes des plantes, ses procedes de preparation et son utilisation
WO1996033270A1 (fr) 1995-04-20 1996-10-24 American Cyanamid Company Produits resistant a des herbicides elabores a partir de structures
US5876739A (en) 1996-06-13 1999-03-02 Novartis Ag Insecticidal seed coating
US20050188434A1 (en) 1997-04-03 2005-08-25 Michael Spencer Method for plant breeding
US20060059581A1 (en) 1997-04-03 2006-03-16 Dekalb Genetics Corporation Method of breeding glyphosate resistant plants
WO1998044140A1 (fr) 1997-04-03 1998-10-08 Dekalb Genetics Corporation Lignees de mais resistantes aux glyphosates
US20050086719A1 (en) 1997-04-03 2005-04-21 Michael Spencer Glyphosate resistant maize lines
US6468747B1 (en) 1998-11-03 2002-10-22 Plant Genetic System, N.V. Glufosinate tolerant rice
WO2000026345A1 (fr) 1998-11-03 2000-05-11 Aventis Cropscience N.V. Riz tolerant au glufosinate
WO2000026356A1 (fr) 1998-11-03 2000-05-11 Aventis Cropscience N. V. Riz tolerant au glufosinate
US20030176428A1 (en) 1998-11-16 2003-09-18 Schneidersmann Ferdinand Martin Pesticidal composition for seed treatment
WO2001031042A2 (fr) 1999-10-29 2001-05-03 Aventis Cropscience N.V. Plantes brassica male sterile et procedes de production de ces plantes
WO2001041558A1 (fr) 1999-12-08 2001-06-14 Aventis Cropscience N.V. Colza oleagineux d'hiver hybrides et son procede de production
US20030188347A1 (en) 1999-12-08 2003-10-02 Both Greta De Hybrid winter oilseed rape and methods for producing same
WO2001051654A2 (fr) 2000-01-11 2001-07-19 Bayer Cropscience N.V. Procedes et assortiments de materiel permettant d'identifier l'evenement elite gat-zm1 dans les echantillons biologiques
US20010029014A1 (en) 2000-01-11 2001-10-11 Beuckeleer Marc De Methods and kits for identifying elite event GAT-ZM1 in biological samples
US20070292854A1 (en) 2000-06-22 2007-12-20 Behr Carl F Corn event PV-ZMGT32(nk603) and compositions and methods for detection thereof
US20020102582A1 (en) 2000-09-13 2002-08-01 Levine Elaine B. Corn event MON810 and compositions and methods for detection thereof
WO2002028186A2 (fr) 2000-10-06 2002-04-11 Monsanto Technology, Llc Traitement de semences avec des melanges d'insecticides
US20020120964A1 (en) 2000-10-25 2002-08-29 Rangwala Tasneem S. Cotton event PV-GHGT07(1445) and compositions and methods for detection thereof
WO2002034946A2 (fr) 2000-10-25 2002-05-02 Monsanto Technology Llc Mecanisme biochimique de plant de coton pv-ghgt07(1445), compositions et techniques de detection de celui-ci
US20080070260A1 (en) 2000-10-30 2008-03-20 Rachel Krieb Canola event PV-BNGT04(RT73) and compositions and methods for detection thereof
WO2002036831A2 (fr) 2000-10-30 2002-05-10 Monsanto Technology Llc Colza canola pv-bngt(rt73), compositions et procedes de detection correspondants
US20090265817A1 (en) 2000-11-30 2009-10-22 Ses Europe N.V./S.A. T227-1 flanking sequence
WO2002044407A2 (fr) 2000-11-30 2002-06-06 Ses Europe N.V. Séquence des flancs de t227-1
WO2002080675A1 (fr) 2001-03-21 2002-10-17 Monsanto Technology, Llc Procede permettant de commander la liberation de principes actifs agricoles de semences traitees de plantes
WO2002096882A1 (fr) 2001-05-31 2002-12-05 Nihon Nohyaku Co., Ltd. Derives d'anilide substitues, produits intermediaires de ces derives, produits chimiques agricoles et horticoles et leur utilisation
WO2002100163A2 (fr) 2001-06-11 2002-12-19 Monsanto Technology Llc Evenement mon15985 du coton et compositions et procedes servant a sa detection
US20040250317A1 (en) 2001-06-11 2004-12-09 Huber Scott A Cotton event moni5985 and compositions and methods for detection thereof
WO2003013224A2 (fr) 2001-08-06 2003-02-20 Bayer Bioscience N.V. Cotonniers avec tolerance aux herbicides et procedes de production et d'identification de ces cotonniers
US20030097687A1 (en) 2001-08-06 2003-05-22 Linda Trolinder Herbicide tolerant cotton plants and methods for producing and identifying same
WO2003052073A2 (fr) 2001-12-17 2003-06-26 Syngenta Participations Ag Nouvel evenement du mais
WO2003106457A1 (fr) 2002-06-14 2003-12-24 Syngenta Limited Derives de spiroindolinepiperidine
US20060095986A1 (en) 2002-07-29 2006-05-04 Cavato Tracey A Corn event pv-zmir13 (mon863) plants and compositions and methods for detection thereof
WO2004011601A2 (fr) 2002-07-29 2004-02-05 Monsanto Technology, Llc Mais pv-zmir13 designe mon863, composition et procedes de detection
US20060130175A1 (en) 2002-10-29 2006-06-15 Ellis Daniel M Cot102 insecticidal cotton
WO2004039986A1 (fr) 2002-10-29 2004-05-13 Syngenta Participations Ag Coton insecticide cot102
US20060162007A1 (en) 2002-12-05 2006-07-20 Monsanto Technology Llc Bentgrass event asr-368 and compositions and methods for detection thereof
WO2004053062A2 (fr) 2002-12-05 2004-06-24 Monsanto Technology Llc Evenement associe a l'agrostide asr-368 et compositions et procedes de detection de la presence de celle-ci
WO2004072235A2 (fr) 2003-02-12 2004-08-26 Monsanto Technology Llc Evenement mon 88913 de plant de coton et procedes de detection correspondants
US20060059590A1 (en) 2003-02-12 2006-03-16 Monsanto Technology Llc Cotton event mon 88913 and compositions and methods for detection thereof
WO2004074492A1 (fr) 2003-02-20 2004-09-02 Kws Saat Ag Betteraves sucrieres tolerant le glyphosate
US20040172669A1 (en) 2003-02-28 2004-09-02 Josef Kraus Glyphosate tolerant sugar beet
WO2004099447A2 (fr) 2003-05-02 2004-11-18 Dow Agrosciences Llc Mais tc1507 et procedes de detection de celui-ci
US20050039226A1 (en) 2003-05-02 2005-02-17 Dow Agrosciences Llc Corn event TC1507 and methods for detection thereof
WO2004099160A1 (fr) 2003-05-12 2004-11-18 Sumitomo Chemical Company, Limited Composes de pyrimidine et compostion de lutte contre les animaux nuisibles contenant ces composes
WO2005035486A1 (fr) 2003-10-02 2005-04-21 Basf Aktiengesellschaft 2-cyanobenzenesulfonamides destines a lutter contre les animaux nuisibles
US20070067868A1 (en) 2003-12-01 2007-03-22 Negrotto David V Insect resistant cotton plants and methods of detecting the same
WO2005054479A1 (fr) 2003-12-01 2005-06-16 Syngenta Participations Ag Cotonnier resistant aux insectes et procedes pour detecter celui-ci
WO2005054480A2 (fr) 2003-12-01 2005-06-16 Syngenta Participations Ag Plants de coton resistant aux insectes et procedes de detection de ces derniers
US20070028322A1 (en) 2003-12-11 2007-02-01 Dizigan Mark A High lysine maize compositions and methods for detection thereof
WO2005061720A2 (fr) 2003-12-11 2005-07-07 Monsanto Technology Llc Compositions de mais a haute teneur en lysine et methodes de detection correspondantes
WO2005059103A2 (fr) 2003-12-15 2005-06-30 Monsanto Technology Llc Plant de mais mon88017, compositions et procedes de detection associes
US20080028482A1 (en) 2003-12-15 2008-01-31 Beazley Kim A Corn Plant Mon88017 and Compositions and Methods for Detection Thereof
WO2005063094A1 (fr) 2003-12-23 2005-07-14 Koninklijke Philips Electronics N.V. Appareil de preparation de boissons comportant plusieurs chambres de reception de boissons
WO2005077934A1 (fr) 2004-02-18 2005-08-25 Ishihara Sangyo Kaisha, Ltd. Anthranilamides, procédé pour la production de ceux-ci et agents antiparasitaires contenant ceux-ci
WO2005085216A1 (fr) 2004-03-05 2005-09-15 Nissan Chemical Industries, Ltd. Composé benzamide substitué par de l’isoxazoline et agent de contrôle d’organisme nocif
US20080167456A1 (en) 2004-03-25 2008-07-10 Syngenta Participations Ag Corn Event MIR604
WO2005103301A2 (fr) 2004-03-25 2005-11-03 Syngenta Participations Ag Mais mir604
US20070143876A1 (en) 2004-03-26 2007-06-21 Dow Agrosciences Llc Cry1F and Cry1Ac transgenic cotton lines and event-specific identification thereof
WO2005103266A1 (fr) 2004-03-26 2005-11-03 Dow Agrosciences Llc Lignees de coton transgeniques cry1f et cry1ac et leur identification specifique a l'evenement
US20050216969A1 (en) 2004-03-26 2005-09-29 Dow Agrosciences Llc Cry1F and Cry1AC transgenic cotton lines and event-specific identification thereof
US20060070139A1 (en) 2004-09-29 2006-03-30 Pioneer Hi-Bred International, Inc. Corn event DAS-59122-7 and methods for detection thereof
WO2006043635A1 (fr) 2004-10-20 2006-04-27 Kumiai Chemical Industry Co., Ltd. Dérivé de 3-triazolylphénylsulfide et insecticide/acaricide/nématicide incluant ledit dérivé au titre de principe actif
WO2006056433A2 (fr) 2004-11-26 2006-06-01 Basf Aktiengesellschaft Composes de 2-cyano-3-(halo)alcoxy-benzenesulfonamide destines au combat des parasites des animaux
WO2006089633A2 (fr) 2005-02-22 2006-08-31 Bayer Cropscience Ag Cetoenols cycliques substitues par spirocetal
WO2006098952A2 (fr) 2005-03-16 2006-09-21 Syngenta Participations Ag Mais 3272 et procedes pour le detecter
US20060230473A1 (en) 2005-03-16 2006-10-12 Syngenta Participations Ag Corn event 3272 and methods for detection thereof
WO2006100288A2 (fr) 2005-03-24 2006-09-28 Basf Aktiengesellschaft Composes a base de 2-cyanobenzenesulfonamide, destines au traitement des semences
US20080320616A1 (en) 2005-04-08 2008-12-25 Bayer Bioscience N.V. Elite Event A2407-12 and Methods and Kits for Identifying Such Event in Biological Samples
WO2006108674A2 (fr) 2005-04-08 2006-10-19 Bayer Bioscience N.V. Evenement elite a2704-12 et procedes et trousses permettant d'identifier cet evenement dans des prelevements biologiques
US20080196127A1 (en) 2005-04-11 2008-08-14 Bayer Bioscience N.V. Elite Event A5547-127 and Methods and Kits For Identifying Such Event in Biological Samples
WO2006108675A2 (fr) 2005-04-11 2006-10-19 Bayer Bioscience N.V. Evenement elite a5547-127 et procedes et trousses pour l'identification d'un tel evenement dans des echantillons biologiques
US20060282915A1 (en) 2005-05-27 2006-12-14 Monsanto Technology Llc Soybean event MON89788 and methods for detection thereof
WO2006130436A2 (fr) 2005-05-27 2006-12-07 Monsanto Technology Llc Evenement de soja mon89788 et procedes de detection de celui-ci
WO2006128573A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce43-67b
WO2006128572A1 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce46-02a
US20090217423A1 (en) 2005-06-02 2009-08-27 Cayley Patricia J Ce43-67b insecticidal cotton
WO2006128570A1 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide 1143-51b
WO2006128571A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide ce44-69d
WO2006128569A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide 1143-14a
WO2006128568A2 (fr) 2005-06-02 2006-12-07 Syngenta Participations Ag Coton insecticide t342-142
US20100024077A1 (en) 2005-06-02 2010-01-28 Syngenta Participations Ag Ce44-69d insecticidal cotton
US20100050282A1 (en) 2005-08-08 2010-02-25 Bayer Bioscience N.V. Herbicide Tolerant Cotton Plants and Methods for Identifying the Same
WO2007017186A1 (fr) 2005-08-08 2007-02-15 Bayer Bioscience N.V. Cotonniers tolerants aux herbicides et leurs procedes d'identification
WO2007024782A2 (fr) 2005-08-24 2007-03-01 Pioneer Hi-Bred International, Inc. Compositions assurant une tolerance a de multiples herbicides et methodes d'utilisation
WO2007027777A2 (fr) 2005-08-31 2007-03-08 Monsanto Technology Llc Sequences nucleotidiques codant des proteines insecticides
WO2007040280A1 (fr) 2005-10-06 2007-04-12 Nippon Soda Co., Ltd. Cyclic amine compound and pest control agent
WO2007057407A2 (fr) 2005-11-21 2007-05-24 Basf Se Procedes insecticides utilisant des derives de 3-amino-1,2-benzisothiazole
WO2007075459A2 (fr) 2005-12-16 2007-07-05 E. I. Du Pont De Nemours And Company 5-arylisoxazolines pour lutter contre des parasites invertebres
WO2007091277A2 (fr) 2006-02-10 2007-08-16 Maharashtra Hybrid Seeds Company Limited (Mahyco) Aubergine transgenique (solanum melongena) comprenant un evenement ee-i
WO2007101369A1 (fr) 2006-03-09 2007-09-13 East China University Of Science And Technology Méthode de préparation et utilisation de composés présentant une action biocide
WO2007115644A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués
WO2007115646A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués utilisés comme insecticides
WO2007115643A1 (fr) 2006-03-31 2007-10-18 Bayer Cropscience Ag Composés énaminocarbonylés substitués
WO2007140256A1 (fr) 2006-05-26 2007-12-06 Monsanto Technology, Llc Plant et semence de maïs correspondant au produit transgénique mon89034, procédés de détection et utilisation associés
US20080260932A1 (en) 2006-05-26 2008-10-23 Anderson Heather M Corn Plant and Seed Corresponding to Transgenic Event MON89034 and Methods For Detection and Use Thereof
WO2007142840A2 (fr) 2006-06-03 2007-12-13 Syngenta Participations Ag Événement de transformation de maïs mir162
US20090300784A1 (en) 2006-06-03 2009-12-03 Syngenta Participations Ag Corn event mir162
WO2007149134A1 (fr) 2006-06-23 2007-12-27 Dow Agrosciences Llc Procédé pour lutter contre des insectes résistant aux insecticides courants
US20100184079A1 (en) 2006-06-28 2010-07-22 Pioneer Hi-Bred International, Inc. Soybean event 3560.4.3.5 and compositions and methods for the identification and detection thereof
WO2008002872A2 (fr) 2006-06-28 2008-01-03 Pioneer Hi-Bred International, Inc. Événement de soja 3560.4.3.5 et compositions et procedes d'identification et/ou de détection de celui-ci
WO2008009360A2 (fr) 2006-07-20 2008-01-24 Bayer Cropscience Ag Dérivés de n'-cyano-n-halogènalkyle-imidamide
US20080289060A1 (en) 2006-08-24 2008-11-20 Bayer Bioscience N.V. Herbicide tolerant rice plants and methods for identifying same
US20080064032A1 (en) 2006-09-13 2008-03-13 Syngenta Participations Ag Polynucleotides and uses thereof
WO2008112019A2 (fr) 2006-10-30 2008-09-18 Pioneer Hi-Bred International, Inc. Evènement dp-098140-6 du maïs et compositions et procédés pour son identification et/ou sa détection
US20090137395A1 (en) 2006-10-30 2009-05-28 Pioneer Hi-Bred International, Inc. Maize event DP-098140-6 and compositions and methods for the identification and/or detection thereof
US20080312082A1 (en) 2006-10-31 2008-12-18 Kinney Anthony J Soybean event dp-305423-1 and compositions and methods for the identification and/or detection thereof
WO2008054747A2 (fr) 2006-10-31 2008-05-08 E. I. Du Pont De Nemours And Company Événement de soja dp-305423-1, leurs compositions et leurs procédés d'identification et/ou de détection
WO2008066153A1 (fr) 2006-11-30 2008-06-05 Meiji Seika Kaisha, Ltd. Agent antiparasitaire
WO2008067911A1 (fr) 2006-12-04 2008-06-12 Bayer Cropscience Ag Cétoénols spirocycliques substitués par le biphényle
WO2008104503A1 (fr) 2007-03-01 2008-09-04 Basf Se Mélanges actifs pesticides comprenant des composés aminothiazoline
WO2008114282A2 (fr) 2007-03-19 2008-09-25 Maharashtra Hybrid Seeds Company Limited Riz transgénique (oryza sativa) comprenant l'événement pe-7 et son procédé de détection
US20100077501A1 (en) 2007-04-05 2010-03-25 Bayer Bioscience N.V. Insect resistant cotton plants and methods for identifying same
WO2008122406A1 (fr) 2007-04-05 2008-10-16 Bayer Bioscience N.V. Plants de coton résistant aux insectes et leurs procédés d'identification
WO2008151780A1 (fr) 2007-06-11 2008-12-18 Bayer Bioscience N.V. Cotonniers résistant aux insectes comprenant un événement élite ee-gh6 et leurs procédés d'identification
WO2009049851A1 (fr) 2007-10-15 2009-04-23 Syngenta Participations Ag Dérivés pyrrolidine dione spirohétérocycliques utiles comme pesticides
WO2009064652A1 (fr) 2007-11-15 2009-05-22 Monsanto Technology Llc Plante et graine de soja correspondant à l'événement transgénique mon87701 et procédés pour les détecter
US20090130071A1 (en) 2007-11-15 2009-05-21 Ai-Guo Gao Soybean Plant And Seed Corresponding To Transgenic Event MON87701 And Methods For Detection Thereof
WO2009100188A2 (fr) 2008-02-08 2009-08-13 Dow Agrosciences Llc Procédés de détection de l’événement de maïs das-59132
WO2009103049A2 (fr) 2008-02-14 2009-08-20 Pioneer Hi-Bred International, Inc. Evénement spt flanquant l'adn génomique végétal et procédés d'identification de l'événement spt
US20090210970A1 (en) 2008-02-14 2009-08-20 Pioneer Hi-Bred International, Inc. Plant Genomic DNA Flanking SPT Event and Methods for Identifying SPT Event
WO2009102873A1 (fr) 2008-02-15 2009-08-20 Monsanto Technology Llc Plante de soja et graine correspondant à l’évènement transgénique mon87769 et leurs procédés de détection
US20110067141A1 (en) 2008-02-15 2011-03-17 Byron Froman Soybean plant and seed corresponding to transgenic event mon87769 and methods for detection thereof
WO2009111263A1 (fr) 2008-02-29 2009-09-11 Monsanto Technology Llc Plant de maïs correspondant au produit transgénique mon87460 et compositions et procédés de détection associés
US20110138504A1 (en) 2008-02-29 2011-06-09 Monsanto Technology Llc Corn plant event mon87460 and compositions and methods for detection thereof
WO2009116106A1 (fr) 2008-03-21 2009-09-24 Trentino Sviluppo S.P.A. Trichoderma atroviride sc1 pour la lutte biologique contre les maladies fongiques des végétaux
WO2010005692A2 (fr) 2008-06-16 2010-01-14 E. I. Du Pont De Nemours And Company Carbonyl-amidines cycliques insecticides
JP2010018586A (ja) 2008-07-14 2010-01-28 Meiji Seika Kaisha Ltd Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤
WO2010006713A2 (fr) 2008-07-17 2010-01-21 Bayer Cropscience Ag Composés hétérocycliques utilisés comme pesticides
WO2010024976A1 (fr) 2008-08-29 2010-03-04 Monsanto Technology Llc Plante et semences de soja correspondant à l’événement transgénique mon87754 et procédés pour détection de celui-ci
US20100080887A1 (en) 2008-09-29 2010-04-01 Monsanto Technology Llc Soybean Transgenic Event MON87705 and Methods for Detection Thereof
WO2010037016A1 (fr) 2008-09-29 2010-04-01 Monsanto Technology Llc Événement transgénique de soja t mon87705 et procédés pour la détection de celui-ci
WO2010077816A1 (fr) 2008-12-16 2010-07-08 Syngenta Participations Ag Evénement transgénique du maïs 5307
WO2010069502A2 (fr) 2008-12-18 2010-06-24 Bayer Cropscience Ag Amides d'acide anthranilique substitués par tétrazol, utilisés comme pesticides
WO2010076212A1 (fr) 2008-12-19 2010-07-08 Syngenta Participations Ag Événement de betterave sucrière transgénique gm rz13
WO2010074751A1 (fr) 2008-12-26 2010-07-01 Dow Agrosciences, Llc Compositions insecticides stables renfermant de la sulfoximine
WO2010074747A1 (fr) 2008-12-26 2010-07-01 Dow Agrosciences, Llc Compositions d'insecticide stables et procédés de production associés
WO2010080829A1 (fr) 2009-01-07 2010-07-15 Basf Agrochemical Products B.V. Évènement de soja 127 et procédés apparentés
WO2010117735A1 (fr) 2009-03-30 2010-10-14 Monsanto Technology Llc Évènement 17314 de riz transgénique et ses procédés d'utilisation
WO2010117737A1 (fr) 2009-03-30 2010-10-14 Monsanto Technology Llc Evénement de riz transgénique 17053 et ses procédés d'utilisation
WO2011022469A2 (fr) 2009-08-19 2011-02-24 Dow Agrosciences Llc Événement das-40278-9 d'aad-1, lignées transgéniques de maïs connexes et identification spécifique d'événement de celui-ci
WO2011034704A1 (fr) 2009-09-17 2011-03-24 Monsanto Technology Llc Variété transgénique mon 87708 du soja et ses méthodes d'utilisation
WO2011049233A1 (fr) 2009-10-23 2011-04-28 Sumitomo Chemical Company, Limited Composition de lutte contre des animaux nuisibles
WO2011062904A1 (fr) 2009-11-23 2011-05-26 Monsanto Technology Llc Événement du maïs transgénique mon 87427 et échelle de développement relative
WO2011066384A1 (fr) 2009-11-24 2011-06-03 Dow Agrosciences Llc Événement 416 de la transformation aad-12, lignées de soja transgéniques associées, et leur identification spécifique à l'événement
WO2011066360A1 (fr) 2009-11-24 2011-06-03 Dow Agrosciences Llc Détection de l'événement 416 du soja aad-12
WO2011075595A1 (fr) 2009-12-17 2011-06-23 Pioneer Hi-Bred International, Inc. Maïs dp-043a47-3 et procédés de détection associés
WO2011075593A1 (fr) 2009-12-17 2011-06-23 Pioneer Hi-Bred International, Inc. Maïs dp-040416-8 et procédés de détection associés
WO2011084621A1 (fr) 2009-12-17 2011-07-14 Pioneer Hi-Bred International, Inc. Evénement de transformation dp-004114-3 du maïs et son procédé de détection
WO2011084632A1 (fr) 2009-12-17 2011-07-14 Pioneer Hi-Bred International, Inc. Evénement de maïs dp-032316-8 et ses procédés de détection
CN102057925A (zh) 2011-01-21 2011-05-18 陕西上格之路生物科学有限公司 一种含噻虫酰胺和生物源类杀虫剂的杀虫组合物

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
"Current Protocols in Molecular Biology", 1987
"Manual on development and use of FAO and WHO specifications for pesticides", 2004, FAO/WHO JOINT MEETING ON PESTICIDE SPECIFICATIONS
"The Pesticide Manual", 2009, BRITISH CROP PROTECTION COUNCIL
A. KHAN ET AL., FEMS MICROBIOLOGY LETTERS, vol. 227, 2003, pages 107 - 111
BAUR ET AL., PESTICIDE SCIENCE, vol. 51, 1997, pages 131 - 152
R. WEGLER: "Chemie der Pflanzenschutz- und Schadlingsbekampfungsmittel", vol. 2, 1970, SPRINGER VERLAG, pages: 401 - 412
S. KIEWNICK, BIOLOGICAL CONTROL, vol. 38, 2006, pages 179 - 187

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11793202B2 (en) 2013-06-26 2023-10-24 Indigo Ag, Inc. Methods of use of seed-origin endophyte populations
US11754553B2 (en) 2013-09-04 2023-09-12 Indigo Ag, Inc. Agricultural endophyte-plant compositions, and methods of use
US11771090B2 (en) 2013-11-06 2023-10-03 The Texas A&M Unversity System Fungal endophytes for improved crop yields and protection from pests
US11753618B2 (en) 2013-12-24 2023-09-12 Indigo Ag, Inc. Method for propagating microorganisms within plant bioreactors and stably storing microorganisms within agricultural seeds
US11747316B2 (en) 2014-06-26 2023-09-05 Ait Austrian Institute Of Technology Gmbh Plant-endophyte combinations and uses therefor
EP2962567A1 (fr) * 2014-07-01 2016-01-06 Basf Se Mélanges ternaires comprenant des biopesticides et au moins deux insecticides chimiques
US11751571B2 (en) 2015-05-01 2023-09-12 Indigo Ag, Inc. Isolated complex endophyte compositions and methods for improved plant traits
US11819027B2 (en) 2015-06-08 2023-11-21 Indigo Ag, Inc. Streptomyces endophyte compositions and methods for improved agronomic traits in plants
US11751515B2 (en) 2015-12-21 2023-09-12 Indigo Ag, Inc. Endophyte compositions and methods for improvement of plant traits in plants of agronomic importance
US11766045B2 (en) 2016-12-01 2023-09-26 Indigo Ag, Inc. Modulated nutritional quality traits in seeds
US11807586B2 (en) 2016-12-23 2023-11-07 The Texas A&M University System Fungal endophytes for improved crop yields and protection from pests
US11985931B2 (en) 2017-03-01 2024-05-21 Indigo Ag, Inc. Endophyte compositions and the methods for improvement of plant traits
US11882838B2 (en) 2017-04-27 2024-01-30 The Flinders University Of South Australia Bacterial inoculants
CN110117545B (zh) * 2018-02-07 2021-12-21 南京农业大学 一种具有Cr(VI)耐性及还原能力的外生菌根真菌及其应用
CN110117545A (zh) * 2018-02-07 2019-08-13 南京农业大学 一种具有Cr(VI)耐性及还原能力的外生菌根真菌及其应用
CN111557309A (zh) * 2019-01-25 2020-08-21 河南勇冠乔迪农业科技有限公司 一种棉铃虫核型多角体病毒悬浮剂

Also Published As

Publication number Publication date
WO2014086753A3 (fr) 2014-08-14

Similar Documents

Publication Publication Date Title
US9693565B2 (en) Composition comprising biological control agents
AU2013269662B2 (en) Compositions comprising a biological control agent and an insecticide
US9730455B2 (en) Composition comprising a biological control agent and an insecticide
US9867377B2 (en) Composition comprising a biological control agent and an insecticide
EP2925145A2 (fr) Composition comprenant des agents de lutte biologique
EP2925143A2 (fr) Composition comprenant un agent de lutte biologique et un insecticide
IL235491A (en) Preparations containing biological control and insecticide
WO2013178661A1 (fr) Compositions comprenant un agent de lutte biologique et un insecticide
WO2014086753A2 (fr) Composition comprenant des agents de lutte biologique
WO2014086747A2 (fr) Composition comprenant un agent de lutte biologique et un fongicide
WO2013178660A1 (fr) Compositions comprenant un biocide et un insecticide
CA2882671A1 (fr) Composition comprenant un melange pesticide a base de terpene et un pesticide biologique
WO2014086764A2 (fr) Composition comprenant un agent de lutte biologique et un fongicide
WO2014086756A1 (fr) Composition comprenant un agent de lutte biologique et un insecticide
WO2014086776A2 (fr) Composition comprenant un agent de lutte biologique et un fongicide
CA2898792A1 (fr) Compositions comportant un agent de lutte biologique a base de streptomyces et un autre agent de lutte biologique
EP2925141A2 (fr) Composition comprenant un agent de lutte biologique et un fongicide
WO2015160618A1 (fr) Compositions comprenant de la ningnanmycine et un agent de lutte biologique

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13798696

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 13798696

Country of ref document: EP

Kind code of ref document: A2