WO2014077906A1 - Dispositifs antimicrobiens destinés à être utilisés avec des dispositifs médicaux, ensembles dispositif médical et procédés associés - Google Patents

Dispositifs antimicrobiens destinés à être utilisés avec des dispositifs médicaux, ensembles dispositif médical et procédés associés Download PDF

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Publication number
WO2014077906A1
WO2014077906A1 PCT/US2013/047159 US2013047159W WO2014077906A1 WO 2014077906 A1 WO2014077906 A1 WO 2014077906A1 US 2013047159 W US2013047159 W US 2013047159W WO 2014077906 A1 WO2014077906 A1 WO 2014077906A1
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WO
WIPO (PCT)
Prior art keywords
antimicrobial
medical device
syringe
coupling
disinfecting
Prior art date
Application number
PCT/US2013/047159
Other languages
English (en)
Inventor
Joel K. FAULKNER
Li Min SHE
Aaron Garcia FAULKNER
Original Assignee
Health Line International Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Line International Corp. filed Critical Health Line International Corp.
Priority to AU2013345415A priority Critical patent/AU2013345415A1/en
Publication of WO2014077906A1 publication Critical patent/WO2014077906A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/16—Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • A61M39/18—Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/16—Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • A61M39/162—Tube connectors; Tube couplings having provision for disinfection or sterilisation with antiseptic agent incorporated within the connector

Definitions

  • the disclosure generally relates to medical devices generally and antimicrobial devices for use with medical devices and related assemblies and methods.
  • embodiments of the disclosure relate to antimicrobial devices that are configured to be initially coupled to a medical device and utilized in disinfecting at least a portion of a medical device, such as, one or more portions of a medical device for delivering fluid to and/or sampling fluid from a subject.
  • pathogens include microorganisms such as bacteria and viruses.
  • bloodstream infections which may be caused by microorganisms that enter patients via intravascular catheters, are a significant cause of illness and excess medical costs and may result in serious infections or death.
  • cleaning a potentially contaminated surface of a medical device includes treating the surface with an alcohol swab.
  • alcohol swabs include cotton gauze soaked in, e.g., isopropyl alcohol or ethanol.
  • the swab is typically applied by a healthcare provider and wiped across a surface of the medical device. As the alcohol applied by the pad dries, it destroys microorganisms.
  • Impregnating medical devices, such as catheters, with various other known antimicrobial agents is another approach for reducing the chances of contamination of the medical device.
  • Other devices comprising a cap for cleaning a medical device include United States Patent Application Publication No.
  • IV intravenous
  • an antimicrobial device including a disinfecting portion comprising a chamber including an amount of antimicrobial substance and a coupling portion configured to secure the antimicrobial device to at least a portion of a medical device.
  • a medical device assembly including an antimicrobial device and a syringe having a needle hub, wherein the coupling portion of the antimicrobial device is engaged with a connection portion of the syringe at the needle hub.
  • the method includes removing an antimicrobial device from a first device, cleaning a portion of a second device with an amount of antimicrobial substance contained in the antimicrobial device, and removing the antimicrobial device from the portion of the second device.
  • the antimicrobial device includes a disinfecting portion comprising a chamber including an amount of antimicrobial substance and an engagement feature for retaining a portion of a medical device to be disinfected.
  • the disinfecting portion is positioned at a first end portion of the antimicrobial device.
  • the antimicrobial device further includes a coupling portion comprising a female Luer connection for coupling with at least a portion of a male Luer connection of a medical device.
  • the coupling portion is positioned at a second end portion of the antimicrobial device opposing the first end portion.
  • the syringe includes a needle hub and the coupling portion of the antimicrobial device is engaged with and forms an initial sterilized seal with a male Luer connection of the syringe at the needle hub.
  • FIG. 1 illustrates a perspective view of an antimicrobial device in accordance with an embodiment of the disclosure.
  • FIG. 2 illustrates a cross-sectional side view of the antimicrobial device shown in FIG. 1.
  • FIG. 3 illustrates another cross-sectional side view of the antimicrobial device shown in FIG. 1 including a volume of antiseptic material within the antimicrobial device.
  • FIG. 4 illustrates a cross-sectional side view of an antimicrobial device in accordance with another embodiment of the disclosure.
  • FIG. 5 illustrates a cross-sectional side view of a medical device assembly including an antimicrobial device coupled to a portion of a medical device in accordance with yet another embodiment of the disclosure.
  • FIG. 6 illustrates an enlarged portion of the medical device assembly shown in
  • FIG. 5 is a diagrammatic representation of FIG. 5.
  • FIGS. 7 through 10 illustrate cross-sectional side views of various configurations disinfecting portions of antimicrobial devices in accordance with additional embodiments of the disclosure.
  • FIG. 1 1 illustrates a cross-sectional side view of an antimicrobial device such as, for example, the antimicrobial device shown in FIGS. 1 through 6 received on a portion of another medical device including a threaded portion.
  • antimicrobial devices as described herein may be utilized to disinfect potentially contaminated surfaces of various devices (e.g., medical devices).
  • Related assemblies and methods are also disclosed herein.
  • Such antimicrobial devices may be configured to include a first portion having a volume of antimicrobial substance therein.
  • the volume of antimicrobial substance may comprise a disinfectant and/or antiseptic (e.g., a disinfectant and/or antiseptic in a fluid state) such as, for example, alcohol (e.g., isopropyl alcohol) at various concentrations (e.g., 50 to 90%), ethanol at various concentrations (e.g., ranging from 50 to 95%), and combinations of these and any other suitable disinfectant and/or antiseptics.
  • the first portion of the device may used to protect (e.g., by covering a portion of the medical device) and/or disinfect a portion of medical device by receiving the portion of the medical device (e.g., at least temporarily) within the cap.
  • such antimicrobial devices reduce the likelihood of microorganisms entering the bloodstream of a subject via a medical device or assembly configured to deliver fluid to a subject and/or remove a fluid from a subject.
  • the antimicrobial device may be utilized with one or more portions of fluid flow or fluid delivery systems such as, for example, an intravenous (IV) device that delivers substances (e.g., fluid) to and from one or more veins of a subject.
  • IV devices may include a peripheral IV line having a cannula in communication with the vasculature of a subject.
  • the IV device may include one or more connections, valves, and access ports for delivering fluids to and from the subject that may become contaminated while the IV device is connected to the subject (e.g., in fluid communication with one or more portion of subject's internal systems).
  • the peripheral IV line may include one or more of needle injection sites (e.g., y-sites), needleless injection sites (e.g., a luer-activated valve (LAV)), and other fluid transfer devices.
  • LAV luer-activated valve
  • Antimicrobial devices as disclosed herein may be utilized with any such connectors, valves, and access ports in such fluid flow or fluid delivery systems.
  • the antimicrobial devices disclosed herein also include a second portion (e.g., a second end) for coupling to a medical device (e.g., the same medical device to be disinfected or a different medical device).
  • a medical device e.g., the same medical device to be disinfected or a different medical device.
  • the first, disinfecting end of the antimicrobial device may be utilized to disinfect portions of the medical device that are exposed to potential contamination during use.
  • the first, disinfecting end of the antimicrobial device may also be at least temporarily (e.g., transiently, for a selected period a time) connected to (e.g., coupling and retaining) one or more portions of a medical device, such as, the various portions of fluid systems discussed above in order to disinfect and/or protect portions of the medical device that are exposed to potential contamination during use (e.g., during use with a subject).
  • the antimicrobial device may disinfect and protect a portion of the medical device from further contamination as the antimicrobial device remains secured to the medical device in disinfecting contact with the portion of the medical device.
  • the second, coupling end of the antimicrobial device may include a coupling device (e.g., threads, such as a Luer connection) for coupling to the same medical device to be disinfected or a different medical device.
  • a coupling device e.g., threads, such as a Luer connection
  • many medical devices e.g., a syringe
  • a cover e.g., a cap
  • an engagement feature e.g., a threaded Luer connector
  • the coupling end of the antimicrobial device disclosed herein may perform the same or a similar function by sealing a portion of a medical device (e.g., before use). However, unlike typical sealing caps, the antimicrobial device may further provide a disinfecting portion for use in disinfecting a portion of the same medical device to which the coupling end is attached or disinfecting another medical device entirely.
  • the first, disinfecting end of such antimicrobial devices is configured to connect and secure to a portion of a medical including threaded connection (e.g., threads of a Luer connection).
  • the first, disinfecting end of such antimicrobial devices is configured to connect and secure to both a portion of a medical device lacking a threaded connection and/or a portion of a medical including threaded connection (e.g., threads of a Luer connection).
  • the antimicrobial device may be configured to connect and secure to a portion of medical device with or without a threaded connection.
  • the antimicrobial device includes a flexible member (e.g., a membrane) configured to engage with a non-threaded portion (e.g., a portion having a smooth surface, a flat surface, an uneven non-threaded surface, or combinations thereof) of an access port of a medical device (e.g., a needle injection site of an IV device).
  • a non-threaded portion e.g., a portion having a smooth surface, a flat surface, an uneven non-threaded surface, or combinations thereof
  • the flexible membrane of the antimicrobial device may also engage with a portion of a threaded portion (e.g., threads of Luer connection) of an access port of a medical device (e.g., a needleless injection site of an IV device).
  • the flexible member alone may engage and secure the threaded portion (e.g., the threads) of the medical device to retain the portion of the medical device within a housing of the antimicrobial device without the need for a set of complementary threads formed on the housing of the antimicrobial device.
  • the flexible member or membrane of the antimicrobial device may be flexible in the sense that the membrane is easily deformable by a medical practitioner as the practitioner installs and removes the antimicrobial device from the portion of the medical by hand.
  • the stiffness of the flexible member may be selected based on the configuration of the flexible member of the antimicrobial device.
  • FIG. 1 illustrates a perspective view of an antimicrobial device 100. As shown in FIG.
  • the antimicrobial device 100 includes a housing 102 and a sealing member 104.
  • the sealing member 104 may comprise any suitable nonporous material configured to at least partially seal a volume of fluid within the housing 102 of the antimicrobial device 100.
  • the sealing member 104 may include pull-tab (e.g., a metal tab formed from a foil, polymer tab, etc.) having a first portion sealed about the housing 102 and a second portion for a practitioner to grab in order to remove the sealing member 104. It is noted that while the embodiment of FIG.
  • the sealing member covers all of the antimicrobial device 100 and a portion of the medical device to which it is coupled to seal the antimicrobial device 100 to the medical device (e.g., a shrink wrap covering the antimicrobial device 100 and the coupling between the antimicrobial device 100 and the medical device).
  • the antimicrobial device 100 includes a disinfecting portion (e.g., disinfecting end 106) for disinfecting at least a portion of a medical device, which is sealed by the sealing member 104, and a coupling portion (e.g., coupling end 108) for coupling to a portion of a medical device (e.g., to a connection portion of the medical device).
  • the antimicrobial device 100 includes the disinfecting end 106 and the coupling end 108 positioned on opposing ends of the housing 102 of the antimicrobial device 100.
  • the disinfecting portion and the coupling portion of the antimicrobial device is positioned at any suitable location on the housing of the antimicrobial device.
  • the coupling end 108 of the antimicrobial device 100 includes a connection portion 1 10 (e.g., threads 1 12 forming a threaded connection portion such as a female Luer connection).
  • the coupling end 108 includes an opening 1 14 and a chamber 1 15 (FIG. 2) for receiving a portion of a medical device (e.g., at least a portion of a male Luer connection).
  • FIGS. 2 and 3 illustrate cross-sectional side views of the antimicrobial device 100, where, for clarity, FIG. 2 shows the antimicrobial device 100 without a volume of antimicrobial substance positioned in the antimicrobial device 100 and FIG. 3 shows the antimicrobial device 100 with the volume of antimicrobial substance 124 positioned in the antimicrobial device 100.
  • the disinfecting end 106 includes an opening 116 and a chamber 118 for receiving a portion of the medical device to be disinfected.
  • the inner surface 120 of the portion of the housing 102 of the antimicrobial device 100 includes an engagement feature (e.g., threads 122 of a Luer connection) for engaging a portion of a medical device.
  • an engagement feature e.g., threads 122 of a Luer connection
  • a complementary portion of a medical device e.g., threads complementary to threads 122
  • the threads 122 of the disinfecting end 106 may retain (e.g., secure) the portion of the medical device within the chamber 118 until the portion of the medical device is removed (e.g., by unthreading).
  • the antimicrobial device 100 includes a volume of antimicrobial substance 124 within the housing 102, which may be initially sealed in the housing 102 with the sealing member 104 (FIG. 1).
  • the antimicrobial substance 124 may comprise at least one of a disinfectant and antiseptic in a fluid state at various concentrations.
  • the volume of antimicrobial substance 124 will typically include a pad (e.g., sponge material, such as an open-cell foam, felt, fiber matrix, combinations thereof, etc.) configured to retain the antimicrobial substance within the housing 102.
  • the pad of the volume of antimicrobial substance 124 may be at least partially compressible such that the volume of antimicrobial substance 124 may fit within the housing 102 and may at least partially surround a portion of a medical device when the portion of the medical device is received within the housing 102.
  • the chamber 115 of the coupling end 108 may be empty.
  • the chamber 115 comprises a sterile volume (e.g., substantially devoid of any other elements or potential contaminates, apart from the atmosphere in which the chamber 115 is placed or, in some embodiments, the chamber 155 may comprise a vacuum).
  • the sterile volume of the chamber 15 may be configured to receive and seal with a connection portion of a medical device (see, e.g., FIGS. 5 and 6) to provide a sterile interface between the connection portion 110 of the antimicrobial device 100 and a connection portion of a medical device.
  • the antimicrobial device 100 may function as a protective cap and be connected to the medical device during manufacture and/or packaging of the medical device to provide an initial sterilized seal about an open end of the medical device (e.g., an open end or lumen through which fluids are delivered to a subject).
  • an open end of the medical device e.g., an open end or lumen through which fluids are delivered to a subject.
  • FIG. 4 illustrates a cross-sectional side view of an antimicrobial device 200 that may be somewhat similar to and may include one or more features of the antimicrobial device 100 discussed above with regard to FIGS. 1 through 3.
  • the antimicrobial device 200 may include a disinfecting end 206 that is the same or substantially similar to the disinfecting end 106 of the antimicrobial device 100.
  • the antimicrobial device 200 may also include a coupling end 208 having a connection portion 210.
  • the connection portion 210 may be formed as a male Luer connection similar to the configuration of the disinfecting end 206.
  • the connection portion 210 includes an opening 214 and chamber 215 for receiving a portion of a medical device (e.g., a portion of a female Luer connection).
  • FIG. 5 illustrates a cross-sectional side view of a medical device assembly 300 including an antimicrobial device (e.g., antimicrobial device 100) coupled to a portion of a medical device (e.g., syringe 302) and
  • FIG. 6 illustrates an enlarged portion of the medical device assembly 300 shown in FIG. 5.
  • the connection portion 1 10 formed as a female Luer connection
  • a complementary connection portion 304 e.g., a male Luer connection
  • the coupling end 108 of the antimicrobial device 100 may act to seal (e.g., to maintain sterility) an opening 306 (e.g., lumen) of the syringe 302 at the needle hub 308.
  • the coupling end 108 of the antimicrobial device 100 may be used to form an initial seal (e.g., prior to use of the syringe 302) that at least substantially prevents contaminants from entering the syringe 302 (e.g., entering the opening 306 and at the needle hub 308 and/or the chamber 310 within the barrel 312 of the syringe 302).
  • the medical device assembly 300 may include an additional sealing layer (e.g., shrink wrap) positioned over the interface between the antimicrobial device 100 and the syringe 302.
  • the antimicrobial device 100 may be removed from the syringe 302, thereby enabling the syringe 302 to be utilized separate from the antimicrobial device 100. Similarly, the antimicrobial device 100 may be utilized separate from the syringe 302 to disinfect a portion of a medical device. For example, the antimicrobial device 100 may be utilized to disinfect a needleless injection site before fluid is introduced into an rv device to which the needleless injection site is connected with the syringe 302. In some embodiments, the antimicrobial device 100 may also be reattached to the connection portion of the syringe 302 after being removed for an initial use of the syringe if necessary or desirable.
  • FIGS. 7 through 10 illustrate cross-sectional side views of various configurations disinfecting portions of antimicrobial devices.
  • each of antimicrobial devices 400, 500, 600, 700 includes a connection portion for coupling to a portion of a medical device that may, in some embodiments, be similar or the same as at least one of the connection portion 110 shown and described with reference to FIGS. 1 through 3 and the connection portion 210 shown and described with reference to FIG. 4.
  • each of antimicrobial devices 400, 500, 600, 700 includes a connection portion that comprises a male Luer connection or a female Luer connection.
  • antimicrobial device 400 includes a disinfecting end 406 having a volume of antimicrobial substance 424 initially sealed (e.g., by sealing member 404) within the housing 402.
  • the disinfecting end 406 includes an engagement feature configured as a membrane 408.
  • the disinfecting end 406 may be similar or the same as the antimicrobial devices disclosed in United States Provisional Patent Application Serial No. 61/663,287 to Faulkner et al., filed June 22, 2012, the disclosure of which is hereby incorporated herein in its entirety by this reference.
  • the membrane 408 e.g., a flexible membrane
  • the membrane 408 includes an opening 409 for receiving a portion of a medical device.
  • antimicrobial device 500 includes a disinfecting end 506 having a volume of antimicrobial substance 524 initially sealed (e.g., by sealing member 504) within the housing 502. Similar to antimicrobial device 400 (FIG. 7), the disinfecting end 506 of antimicrobial device 500 also includes an engagement feature configured as a membrane 508. However, membrane 508 includes a throat portion 510. As also disclosed in Provisional Patent Application Serial No.
  • the membrane 508 (e.g., a flexible membrane) includes the throat portion 510 extending into the housing 502 and an opening 509 formed by throat portion 510 for receiving a portion of a medical device.
  • the membrane 508 is configured to at least partially yield (e.g., elastically yield) about the portion of the medical device when inserted within the housing 502 to disinfect and at least temporarily retain the portion of the medical device within the housing 502.
  • the throat portion 510 may be formed to have a substantially cylindrical shape (e.g., a cylinder being coaxial with the housing 502) and may extend from a portion of the membrane 508 into the housing 502 (e.g., toward the volume of antimicrobial substance 524 within the housing 502).
  • the throat portion 510 may extend around a portion of the medical device received within the housing 502 and act to enhance the coupling (and retaining) of the portion of the medical device in the housing 502 by the membrane 508.
  • antimicrobial device 600 includes a disinfecting end 606 having a volume of antimicrobial substance 624 initially sealed (e.g., by sealing member 604) within the housing 602. Similar to antimicrobial devices 400, 500 (FIGS. 7 and 8), the disinfecting end 606 of antimicrobial device 600 includes an engagement feature configured as a membrane 608. However, membrane 608 includes a throat portion 610 having threads 612. For example, the disinfecting end 606 may be similar or the same as the antimicrobial devices disclosed in United States Provisional Patent Application Serial No. 61/663,272 to Faulkner et al., filed June 22, 2012, the disclosure of which is hereby incorporated herein in its entirety by this reference. As disclosed in Provisional Patent Application Serial No.
  • the membrane 608 (e.g., a flexible membrane) includes the throat portion 610 extending into the housing 602 and an opening 609 formed by throat portion 610 for receiving a portion of a medical device.
  • the membrane 608 is configured to at least partially yield (e.g., elastically yield) about the portion of the medical device when inserted within the housing 602 to disinfect and at least temporarily retain the portion of the medical device within the housing 602.
  • the throat portion 610 may be formed to have a substantially cylindrical shape (e.g., a cylinder being coaxial with the housing 602) and may extend from a portion of the membrane 608 into the housing 602 (e.g., toward the volume of antimicrobial substance 624 within the housing 602).
  • the throat portion 610 may extend around a portion of the medical device received within the housing 502 and act to enhance the coupling (and retaining) of the portion of the medical device in the housing 602 by the membrane 608.
  • the threads 612 e.g., threads of Luer connector
  • the threads 612 extending from an inner surface of the throat portion 610 of the membrane 608 may be configured to receive and engage with a complementary threaded portion of a medical device.
  • antimicrobial device 700 includes a disinfecting end 706 having a volume of antimicrobial substance 724 initially sealed (e.g., by sealing member 704) within the housing 702. Similar to antimicrobial device 400 (FIG. 7), the disinfecting end 706 of antimicrobial device 700 includes an engagement feature configured as a membrane 708 with an opening 709 formed therein for receiving a portion of a medical device. However, membrane 708 includes a proximal end 710 that is oriented to angularly correspond with an end of a y-site medical device (e.g., an end of a y-site medical device including a needle access valve). As also disclosed in Provisional Patent Application Serial No.
  • the housing 702 may have a proximal end 710 that is angularly offset from the housing 702.
  • the membrane 708 and proximal end 710 of the housing 702 are positioned at an oblique angle relative to a longitudinal axis 712 of the housing 702.
  • the membrane 708 and proximal end 710 of the housing 702 extend in a plane that is not perpendicular to (e.g., does not form a right angle with) the longitudinal axis 712 of the housing 702.
  • the housing 702 may have a substantially trapezoidal shape (e.g., a right trapezoidal shape).
  • the membranes 408, 508, 608, 708 may enable the antimicrobial devices 400,
  • a non-threaded portion of a medical device such as, for example, a needle access site, a threaded portion of a medical device such as, for example, a needleless access site, or combinations thereof.
  • connection portions of the antimicrobial devices discussed herein have been shown as threaded connections (e.g., male or female Luer connections), in other embodiments, the connection portions of the coupling portions of the antimicrobial devices may include any of the membranes 408, 508, 608, 708 discussed above with reference to FIGS. 7 through 10 to couple to a portion of a medical device (e.g., to form an initial sterile seal with the portion of the medical device).
  • FIG. 1 1 illustrates a cross-sectional side view of an antimicrobial device such as, for example, the antimicrobial device 100 shown in FIGS. 1 through 6 received on a threaded portion 22 of a medical device 20.
  • the threaded portion 22 of the medical device 20 e.g., a threaded Luer connection of a needleless access site
  • the threaded portion 22 of the medical device 20 may be inserted into the disinfecting end 106 of the antimicrobial device 100 through the opening 1 16 and into the chamber 1 18.
  • the threads 122 formed in the chamber 1 18 of the antimicrobial device 100 may engage with complementary threads 24 on the threaded portion 22 of the medical device 20 to secure the threaded portion 22 of the medical device 20 within the disinfecting end 106 of the antimicrobial device 100.
  • the disinfecting end 106 may include a different engagement feature (e.g., a membrane as shown in FIGS. 7 through 10) for engaging a portion of the medical device 20 (e.g., the threaded portion 22).
  • the portion of the medical device 20 may be inserted into the disinfecting end 106 of the antimicrobial device 100 in order to at least partially disinfect the portion of the medical device 20 with the volume of antimicrobial substance 124.
  • the disinfecting end 106 of the antimicrobial device 100 is configured to position a portion of the medical device 20 to be disinfected proximate (e.g., in contact with) the antimicrobial substance 124 within the disinfecting end 106.
  • the portion of the medical device 20 may at least partially deform the volume of antimicrobial substance 124 (e.g., the pad holding the volume of antimicrobial substance 124). Referring to FIGS.
  • a portion of an antimicrobial device may be used to form a seal on a medical device, such as, for example, a syringe 302 (e.g., an initial sterilized seal provided after manufacture and/or assembly of a medical device and before a first instance of use of the medical device).
  • the coupling end 108 of the antimicrobial device 100 may be removed from the syringe 302 to enable the syringe 302 to be utilized in a medical procedure.
  • the sealing member 104 of the antimicrobial device 100 may be removed to provide access to the volume of antimicrobial substance 124 within the disinfecting end 106 of the antimicrobial device 100.
  • a portion of a medical device e.g., another medical device 20
  • antimicrobial devices may be formed with one or more suitable materials such as, for example, metals, alloys, polymers, ceramics, combinations thereof, etc.
  • Membranes of the antimicrobial devices, where implemented, may be formed from a flexible material such a silicon or a polymer.
  • the housing of the antimicrobial device may be formed from a polymer such as, for example, a polyethylene, polyvinyl chloride, or other high-density polymers.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne des dispositifs antimicrobiens, qui comprennent une partie de désinfection comportant une chambre ayant une certaine quantité de substance antimicrobienne, et une partie de couplage configurée pour fixer le dispositif antimicrobien à au moins une partie d'un dispositif médical. Des ensembles dispositif médical comprennent un dispositif antimicrobien couplé à un raccord d'aiguille d'une seringue. Des procédés de désinfection d'une partie d'un dispositif comprennent le retrait d'un dispositif antimicrobien d'un premier dispositif et le nettoyage d'une partie d'un second dispositif.
PCT/US2013/047159 2012-11-19 2013-06-21 Dispositifs antimicrobiens destinés à être utilisés avec des dispositifs médicaux, ensembles dispositif médical et procédés associés WO2014077906A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013345415A AU2013345415A1 (en) 2012-11-19 2013-06-21 Antimicrobial devices for use with medical devices, medical device assemblies and related methods

Applications Claiming Priority (2)

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US201261728159P 2012-11-19 2012-11-19
US61/728,159 2012-11-19

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519005A (ja) * 2015-05-05 2018-07-19 コーパック メドシステムズ インコーポレイテッド ねじ付きコネクタポートのクリーニングシステム、方法、及び装置
USD834187S1 (en) 2016-01-18 2018-11-20 Becton, Dickinson And Company Disinfecting cap
CN109045396A (zh) * 2018-07-31 2018-12-21 杨福荣 一种带有消毒装置的留置针输液接头

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