WO2014040366A1 - 苦乔排毒粉及其制备方法 - Google Patents
苦乔排毒粉及其制备方法 Download PDFInfo
- Publication number
- WO2014040366A1 WO2014040366A1 PCT/CN2013/000780 CN2013000780W WO2014040366A1 WO 2014040366 A1 WO2014040366 A1 WO 2014040366A1 CN 2013000780 W CN2013000780 W CN 2013000780W WO 2014040366 A1 WO2014040366 A1 WO 2014040366A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- liver
- tartary buckwheat
- bitter
- powder
- buckwheat
- Prior art date
Links
- 239000000843 powder Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 235000009419 Fagopyrum esculentum Nutrition 0.000 title abstract description 8
- 239000003053 toxin Substances 0.000 title abstract 2
- 231100000765 toxin Toxicity 0.000 title abstract 2
- 241000219051 Fagopyrum Species 0.000 title description 7
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 10
- 235000008397 ginger Nutrition 0.000 claims abstract description 10
- 241000246044 Sophora flavescens Species 0.000 claims abstract description 9
- 238000012545 processing Methods 0.000 claims abstract description 9
- 244000130270 Fagopyrum tataricum Species 0.000 claims abstract description 8
- 235000014693 Fagopyrum tataricum Nutrition 0.000 claims abstract description 8
- 239000003513 alkali Substances 0.000 claims abstract description 6
- 239000006187 pill Substances 0.000 claims abstract description 6
- 150000003839 salts Chemical class 0.000 claims abstract description 6
- 239000002253 acid Substances 0.000 claims abstract description 5
- 239000002775 capsule Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 238000001784 detoxification Methods 0.000 claims description 18
- 239000003814 drug Substances 0.000 claims description 14
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 229910052709 silver Inorganic materials 0.000 claims description 10
- 239000004332 silver Substances 0.000 claims description 10
- 241000234314 Zingiber Species 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000012216 screening Methods 0.000 claims description 3
- 244000163122 Curcuma domestica Species 0.000 claims 1
- 235000003392 Curcuma domestica Nutrition 0.000 claims 1
- 235000003373 curcuma longa Nutrition 0.000 claims 1
- 239000002075 main ingredient Substances 0.000 claims 1
- 235000013976 turmeric Nutrition 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 abstract description 12
- 208000014018 liver neoplasm Diseases 0.000 abstract description 12
- 210000004185 liver Anatomy 0.000 abstract description 11
- 206010003445 Ascites Diseases 0.000 abstract description 6
- 208000004930 Fatty Liver Diseases 0.000 abstract description 6
- 206010019708 Hepatic steatosis Diseases 0.000 abstract description 6
- 230000001476 alcoholic effect Effects 0.000 abstract description 6
- 208000010706 fatty liver disease Diseases 0.000 abstract description 6
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract description 6
- 238000009835 boiling Methods 0.000 abstract description 5
- 208000006454 hepatitis Diseases 0.000 abstract description 5
- 231100000283 hepatitis Toxicity 0.000 abstract description 5
- 238000010025 steaming Methods 0.000 abstract description 5
- 238000007710 freezing Methods 0.000 abstract description 3
- 230000008014 freezing Effects 0.000 abstract description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract description 2
- 244000273928 Zingiber officinale Species 0.000 abstract description 2
- 240000008620 Fagopyrum esculentum Species 0.000 abstract 1
- 241000234435 Lilium Species 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 12
- YVGGHNCTFXOJCH-UHFFFAOYSA-N DDT Chemical compound C1=CC(Cl)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(Cl)C=C1 YVGGHNCTFXOJCH-UHFFFAOYSA-N 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 208000002672 hepatitis B Diseases 0.000 description 5
- 238000011161 development Methods 0.000 description 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 4
- 229910052737 gold Inorganic materials 0.000 description 4
- 239000010931 gold Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000003285 pharmacodynamic effect Effects 0.000 description 3
- 239000002574 poison Substances 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 206010016654 Fibrosis Diseases 0.000 description 2
- 230000007882 cirrhosis Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000029142 excretion Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 239000009313 kushen Substances 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 208000000419 Chronic Hepatitis B Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Definitions
- the invention belongs to the technical field of preparation of medicinal materials, in particular to bitter qiao detox powder and its unique formula and preparation method. Background technique
- Liver disease is a common and extremely harmful disease. According to incomplete statistics, there are more than 100 million people infected with hepatitis B virus in China and 20 million patients with chronic hepatitis B. It is a veritable "hepatitis B big country”. More than 80% of the serious diseases such as liver cirrhosis and liver cancer in our country are developed from hepatitis B. It can be seen that if the study confirms the effectiveness of the drug, the development prospects are considerable.
- the invention provides Shugan Kuaiqiao detoxification powder and a preparation method thereof, and the Kuiqiao detoxification powder has good effects on treating ascites of fatty liver, alcoholic liver, hepatitis, liver cirrhosis, liver cancer, liver cirrhosis and advanced liver cancer, and the pharmaceutical market prospect
- the development space is huge, and the source of medicine is abundant, the technical operation is simple, and the production investment is not large.
- the object of the present invention is to provide a bitter qiao detox powder
- the main components of the bitter qiao detox powder are gold needle silver pot, sophora flavescens, bitter buckwheat, dried ginger, according to the weight ratio: gold needle silver pots account for 10 ⁇ 35%, Sophora flavescens accounts for 10 ⁇ 35%, bitter buckwheat accounts for 15 ⁇ 25%, and dried ginger accounts for 10 ⁇ 25%.
- Another object of the present invention is to provide a method for preparing a bitter detoxification powder, which comprises the following steps:
- Step one screening qualified Chinese medicine decoction pieces and qualified bitter as raw materials
- Step 2 processing and processing the traditional Chinese medicine decoction pieces and tartary buckwheat by freezing, dampness, acid, alkali, salt, leaven, steaming, boiling and baking;
- Step 3 After pulverization, it is made into water pill or capsule, and the package is stored in the library.
- Jinjin silver pot and Sophora flavescens were selected from the Aba Prefecture of Sichuan province, and the bitterness of Yungui was used.
- bitter qiao detox powder firstly, the Chinese herbal medicines and qualified bitter are frozen, wet, sour, alkali, salt, and yeast.
- the prescription is used for constipation, has a special effect, and can be treated for 10 days in a row.
- the prescription is adjusted for the treatment of toothache, and the specific effect can be quickly recovered within a few hours. Loose teeth are naturally reset and stabilized.
- 1 is a flow chart showing the implementation of a method for preparing a bitter detoxification powder according to an embodiment of the present invention. detailed description
- the purpose of the present invention is to provide a bitter detoxification powder, and the main components of the bitter detoxification powder are gold needle silver pot, sophora flavescens, bitter buckwheat, and dried ginger.
- the pharmacodynamic principle of the bitter detoxification powder is rapid excretion of liver poison, indications: fatty liver, alcoholic liver, hepatitis, liver cirrhosis, liver cancer, liver cirrhosis, advanced ascites of liver cancer.
- Step S101 screening qualified products of Chinese medicine decoction pieces and qualified bitter as raw materials
- Step S102 processing and processing the qualified products of Chinese herbal medicine pieces and the qualified bitter buckwheat by means of freezing, dampness, acid, alkali, salt, leaven, steaming, boiling, baking, etc.;
- Step S103 after the pulverization process, is made into a water pill or a plastic bottle, and the package is stored in a library.
- Bitter Qiao Detox Powder is made from traditional Chinese medicines such as Golden Needle Silver Pot, Sophora flavescens, Bitter Ginseng and Dried Ginger. It has the effect of clearing heat and detoxifying. Clinically used for fatty liver, alcoholic liver, hepatitis B, liver cirrhosis, liver ascites, liver cancer and other effects.
- the drug has been used in the private sector for nearly a decade, treating thousands of patients with liver disease. After taking many patients, the effect is very good. Hepatitis B patients taking this drug controlled the symptoms of transaminase in January, and the symptoms of Dasanyang were reduced to Xiaosanyang until the recovery. The symptoms of the patients were significantly improved. A patient with advanced cirrhosis was controlled after taking the drug, and the liver cirrhosis did not continue to develop. Some indicators Turned to negative. According to the feedback results, the bitter detoxification powder has the functions of detoxification, improving immunity and restoring liver function, and has no toxic and side effects except for cold and cold.
- the Kuiqiao detoxification powder provided by the embodiment of the invention and the preparation method thereof, the main components of the liver powder are the golden needle silver pot, the Kushen, the bitter buckwheat, the dried ginger, and the pharmacodynamic principle of the bitter powder is rapidly excreting liver poison, indication : fatty liver, alcoholic liver, hepatitis, liver cirrhosis, liver cancer, liver cirrhosis and advanced ascites of liver cancer; when preparing bitter qiao detox powder, firstly, the qualified Chinese medicine decoction pieces and qualified bitter buckwheat are frozen, wet, acid, alkali, salt, Fermentation, steaming, boiling, baking and other methods processing; after crushing, making water pills or plastic bottles, packaging and storage in the library, the drug market has good prospects, huge development space, rich drug source, simple technical operation, production investment Not big, with strong promotion and application value.
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020147012696A KR20140097169A (ko) | 2012-09-13 | 2013-06-28 | 타타리 메밀 해독 분말 및 그 제조 방법 |
US14/353,714 US20140271954A1 (en) | 2012-09-13 | 2013-06-28 | Toxin Expelling Powder Comprising Root of Buckwheat and Preparation Process Thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012103370105A CN102836408A (zh) | 2012-09-13 | 2012-09-13 | 苦乔排毒粉及其制备方法 |
CN201210337010.5 | 2012-09-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014040366A1 true WO2014040366A1 (zh) | 2014-03-20 |
Family
ID=47364311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2013/000780 WO2014040366A1 (zh) | 2012-09-13 | 2013-06-28 | 苦乔排毒粉及其制备方法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20140271954A1 (zh) |
KR (1) | KR20140097169A (zh) |
CN (1) | CN102836408A (zh) |
WO (1) | WO2014040366A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102836408A (zh) * | 2012-09-13 | 2012-12-26 | 赵淩宏 | 苦乔排毒粉及其制备方法 |
CN104623201B (zh) * | 2015-02-12 | 2018-09-25 | 赵浚宏 | 一种保肝排毒降脂降糖药物及其应用 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1350848A (zh) * | 2000-10-31 | 2002-05-29 | 上海绿谷伟业生态工程有限公司 | 氧化苦参碱在制备治疗丙型病毒性肝炎药物中的应用 |
CN1362249A (zh) * | 2001-07-15 | 2002-08-07 | 王剑飞 | 金骨子清热解毒胶囊 |
CN1425373A (zh) * | 2003-01-08 | 2003-06-25 | 江苏正大天晴药业股份有限公司 | 苦参素缓释制剂及其制备方法 |
WO2003105877A1 (en) * | 2002-06-12 | 2003-12-24 | Medipearl Pte Limited | Pharmaceutical compositions |
CN1480193A (zh) * | 2003-07-18 | 2004-03-10 | 怡 程 | 苦参靶向制剂及其制备方法 |
CN101204573A (zh) * | 2007-12-12 | 2008-06-25 | 中国中医科学院广安门医院 | 一种治疗糖尿病的药物 |
CN102836408A (zh) * | 2012-09-13 | 2012-12-26 | 赵淩宏 | 苦乔排毒粉及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1143509A (zh) * | 1995-08-22 | 1997-02-26 | 张文军 | 一种治疗肠炎、赤皮、烂鳃的中药鱼药 |
JP4615796B2 (ja) * | 2001-11-20 | 2011-01-19 | 株式会社ファンケル | 刺激緩和組成物 |
CN1923237A (zh) * | 2005-09-01 | 2007-03-07 | 何元竹 | 治疗病毒性乙型肝炎的药物及其制备方法 |
-
2012
- 2012-09-13 CN CN2012103370105A patent/CN102836408A/zh active Pending
-
2013
- 2013-06-28 WO PCT/CN2013/000780 patent/WO2014040366A1/zh active Application Filing
- 2013-06-28 US US14/353,714 patent/US20140271954A1/en not_active Abandoned
- 2013-06-28 KR KR1020147012696A patent/KR20140097169A/ko not_active Application Discontinuation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1350848A (zh) * | 2000-10-31 | 2002-05-29 | 上海绿谷伟业生态工程有限公司 | 氧化苦参碱在制备治疗丙型病毒性肝炎药物中的应用 |
CN1362249A (zh) * | 2001-07-15 | 2002-08-07 | 王剑飞 | 金骨子清热解毒胶囊 |
WO2003105877A1 (en) * | 2002-06-12 | 2003-12-24 | Medipearl Pte Limited | Pharmaceutical compositions |
CN1425373A (zh) * | 2003-01-08 | 2003-06-25 | 江苏正大天晴药业股份有限公司 | 苦参素缓释制剂及其制备方法 |
CN1480193A (zh) * | 2003-07-18 | 2004-03-10 | 怡 程 | 苦参靶向制剂及其制备方法 |
CN101204573A (zh) * | 2007-12-12 | 2008-06-25 | 中国中医科学院广安门医院 | 一种治疗糖尿病的药物 |
CN102836408A (zh) * | 2012-09-13 | 2012-12-26 | 赵淩宏 | 苦乔排毒粉及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
US20140271954A1 (en) | 2014-09-18 |
KR20140097169A (ko) | 2014-08-06 |
CN102836408A (zh) | 2012-12-26 |
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