WO2014037613A1 - Procédé et appareil de récupération de déchets pharmaceutiques liquides - Google Patents

Procédé et appareil de récupération de déchets pharmaceutiques liquides Download PDF

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Publication number
WO2014037613A1
WO2014037613A1 PCT/FI2013/050845 FI2013050845W WO2014037613A1 WO 2014037613 A1 WO2014037613 A1 WO 2014037613A1 FI 2013050845 W FI2013050845 W FI 2013050845W WO 2014037613 A1 WO2014037613 A1 WO 2014037613A1
Authority
WO
WIPO (PCT)
Prior art keywords
package
emptying
pharmaceutical
overpressure
underpressure
Prior art date
Application number
PCT/FI2013/050845
Other languages
English (en)
Inventor
Ilpo KRÖGER
Original Assignee
Ipi Medicine Tech Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipi Medicine Tech Oy filed Critical Ipi Medicine Tech Oy
Publication of WO2014037613A1 publication Critical patent/WO2014037613A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65F—GATHERING OR REMOVAL OF DOMESTIC OR LIKE REFUSE
    • B65F1/00—Refuse receptacles; Accessories therefor
    • B65F1/10—Refuse receptacles; Accessories therefor with refuse filling means, e.g. air-locks
    • B65F1/105—Refuse receptacles; Accessories therefor with refuse filling means, e.g. air-locks the filling means being pneumatic, e.g. using suction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00—Other disintegrating devices or methods
    • B02C19/0056—Other disintegrating devices or methods specially adapted for specific materials not otherwise provided for
    • B02C19/0075—Other disintegrating devices or methods specially adapted for specific materials not otherwise provided for specially adapted for disintegrating medical waste
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B3/00—Destroying solid waste or transforming solid waste into something useful or harmless
    • B09B3/0075—Disposal of medical waste
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C9/00—Devices for emptying bottles, not otherwise provided for
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09B—DISPOSAL OF SOLID WASTE NOT OTHERWISE PROVIDED FOR
    • B09B2101/00—Type of solid waste
    • B09B2101/02—Gases or liquids enclosed in discarded articles, e.g. aerosol cans or cooling systems of refrigerators

Definitions

  • the invention relates to a method of recovering liquid pharmaceutical waste.
  • the invention further relates to an apparatus for emptying liquid pharmaceutical waste from a pharmaceutical package.
  • the method is characterized by: arranging a pharmaceutical package to be emptied in an emptying member, arranging a drain tube through a cap of the pharmaceutical package, generating an underpressure or an overpressure in the pharmaceutical package in order to empty the pharmaceutical package of a medicament, and conveying the medicament removed from the pharmaceutical package to a receptacle.
  • the apparatus is characterized in that it comprises: a pump for generating an underpressure and/or an overpressure, at least one emptying member arrangeable in connection with a pharmaceutical package to be emptied for generating an underpressure or an overpressure in the package, and a receptacle connected to the emptying member for receiving pharmaceutical waste, the emptying member comprising a cutting drain tube arrangeable through a cap of the pharmaceutical package.
  • the idea of an embodiment is that an underoverpressure is generated in the pharmaceutical package.
  • the advantage is that risks of the medicament spilling into the environment during emptying are minimized.
  • the idea of an embodiment is that the drain tube penetrating the cap is fixedly arranged in a reception recess of the apparatus.
  • the advantage is that the apparatus is safe to use because the user does not have to handle loose or otherwise exposed needles.
  • the apparatus also comprises a Luer connector.
  • the advantage is that the same apparatus may also be used for emptying packages provided with a Luer-Lok® or Luer-Slip® type mating connector, e.g. pain cartridges and pain syringes, into the same receptacle as those used for some other medicaments.
  • the apparatus also comprises an emptying place for thin glass ampoules.
  • the advantage is that the same apparatus may also be used for emptying thin glass ampoules.
  • the apparatus also comprises an emptying place for syringes.
  • the advantage is that the same apparatus may also be used for emptying syringes, such as contrast medium syringes.
  • Figure 1 is a schematic, partially sectioned view showing a method and an apparatus for recovering liquid pharmaceutical waste
  • FIG 2 schematically shows the apparatus according to Figure 1 from its user interface side
  • FIGS 3A to 3C schematically show some details of the apparatus according to Figure 1.
  • Figure 1 schematically shows a method and an apparatus for recovering liquid pharmaceutical waste
  • Figure 2 shows the apparatus from its user interface side.
  • Such liquid pharmaceutical waste may be e.g. a solution or a medicament in liquid suspension form or an infusion liquid.
  • a bottle comprising a polymer material and provided with a cap made of plastic or rubber,
  • a bag comprising a polymer material, e.g. a bag in a cartridge for a pain pump,
  • the apparatus 10 comprises six package emptying members enabling e.g. glass bottles with screw caps, glass bottles with a puncturable rubber cap, thin glass ampoules, plastic bottles with a puncturable rubber part, bags of a cartridge for a pain pump, and contrast medium syringes to be emptied.
  • six package emptying members enabling e.g. glass bottles with screw caps, glass bottles with a puncturable rubber cap, thin glass ampoules, plastic bottles with a puncturable rubber part, bags of a cartridge for a pain pump, and contrast medium syringes to be emptied.
  • the emptying members comprise a suction tip 3, four emptying places 4a to 4d, and a Luer connector 7. It is to be noted that the number and configuration of the emptying members may also be different. For instance, according to an idea, the apparatus 10 comprises no other emptying members but one emptying place 4a to 4d.
  • the apparatus 10 comprises a pump 5 for generating an underpressure or an overpressure in a package to be emptied.
  • the pump 5 may thus be an underpressure pump or an overpressure pump or a pump enabling both an underpressure and an overpressure to be generated.
  • the apparatus 10 comprises two pumps, a first one for generating an underpressure and a second one for generating an overpressure, enabling a user of the apparatus 10 to choose which pump to use at a given time.
  • the apparatus may comprise a pressure adjuster 16 for adjusting the magnitude of the underpressure or overpressure applied to the package to be emptied.
  • the pressure adjuster 16 may be controlled from a user interface arranged in an emptying unit 1.
  • the apparatus 10 may comprise a pressure accumulator 28 connected to the pump 5 which generates an overpressure in the pressure accumulator.
  • the overpressure generated in the pressure accumulator 28 may be conveyed via an overpressure tube 29 to a selected package located in a particular emptying space 4a to 4d.
  • the operations may be controlled by magnetic valves 32.
  • the apparatus 0 may further comprise a rinsing liquid reservoir 30.
  • a rinsing liquid contained therein may be conveyed via a rinsing liquid tube 31 to the overpressure tube 29 and further to the package.
  • the rinsing liquid may comprise water, for instance.
  • the package may be rinsed with the rinsing liquid when it is empty. The package thus becomes cleaner and recyclable.
  • the apparatus 10 further comprises a necessary number of receptacles 6a to 6b - two in the shown embodiment - in which liquid removed from the packages is stored. According to an idea, the receptacles 6a, 6b together with their pharmaceutical waste are taken to be destroyed.
  • the apparatus 10 further comprises a channel system 9 connecting the pump 5 and the receptacles 6a, 6b to the package emptying members 3, 4a to 4d, 7.
  • discharge air A is preferably filtered in a filter 17, e.g. a HEPA filter or an activated carbon filter, whereafter the discharge air A may be conveyed to a ventilating duct of a building, for instance.
  • the filter 17 removes possible medicament residues from the discharge air.
  • a desired emptying place 4a to 4d provided in the emptying unit 1 is selected to receive the package to be emptied.
  • the emptying place 4a to 4d is provided with a hollow drain tube 11 , e.g. a needle whose tip is shaped to be bevelled and cutting, a hollow blunt piercing tool whose end preferably comprises a cutting surface, or simply a tube with no cutting surfaces.
  • a hollow drain tube 11 e.g. a needle whose tip is shaped to be bevelled and cutting, a hollow blunt piercing tool whose end preferably comprises a cutting surface, or simply a tube with no cutting surfaces.
  • the medicament contained in the package is removed through the drain tube 11 by using underpressure or overpressure.
  • Third and fourth emptying places 4c, 4d comprise a cutting needle or a piercing tool.
  • the needle or the piercing tool penetrates the cap, lid or another closing cover of the package.
  • cap also refers to lids and other closing covers for a package.
  • An advantage of the method is, inter alia, that a vast majority of packaging bottles for liquid medicaments in use comprises a cap made of plastic, rubber or another penetrable material.
  • the package to be emptied may also be arranged in the suction tip 3 so as to enable packages for which no place is provided in the emptying unit 1 itself to be emptied.
  • the drain tube of the suction tip may comprise a cutting or a non-cutting tip.
  • the suction tip 3 is designed to be held in the hand; preferably, it further comprises an operating switch enabling the suction in the suction tip 3 necessary for the emptying to be switched on and off.
  • the suction tip 3 may also be arranged and fitted in the Luer connector 7.
  • the suction tip 3 is connected to the emptying unit 1 by means of a flexible suction tube 12, enabling the position of the suction tip to be changed quite freely.
  • the liquid suctioned by the suction tip 3 may be conveyed to a volume measurement container 2 and therefrom after measurement to the receptacle 6a, 6b by opening a cut-off valve 19.
  • the liquid suctioned by the suction tip 3 is conveyed directly to the receptacle 6a, 6b.
  • the suction tip 3 is further provided with an overpressure tube enabling an overpressure to be generated in the package to be emptied.
  • the package to be emptied may also be arranged in a Luer connector 7 provided with replaceable male or female fittings.
  • Luer connector refers to a connector having standard dimensions and being arrangeable in a standard mating connector.
  • the Luer connector 7 is compatible with at least either a Luer-Lok® or Luer- Slip® type mating connector.
  • the Luer connector 7 is suitable for emptying pain cartridges and pumps in particular. Via the Luer connector 7 the liquid may be conveyed to the volume measurement container 2 enabling the volume of the removed liquid to be measured prior to conveying it to the receptacle 6a, 6b.
  • the user interface of the apparatus is mainly arranged in the emptying unit 1.
  • the user interface comprises push buttons I to V, but naturally the user interface may also be implemented in another manner.
  • the user interface may comprise a foot-operated operating button placed on the floor, for instance.
  • the push buttons I to V are used for controlling the cut-off valve 19 and the magnetic valves 20.
  • the emptying place 4a to 4d connected thereto can be provided with a desired pressure effect, i.e. underpressure or overpressure.
  • the method and the apparatus 0 implementing it empty the package either by means of underpressure, overpressure or by alternating these two.
  • the apparatus may be provided with an adjuster enabling the pressure applied to the package to be changed and adjusted to be overpressure or underpressure.
  • the apparatus 10 When emptying with underpressure, when necessary, the apparatus 10 cuts off the generation of the underpressure in the package and, via a valve, enters substitution air/pressure into ' the package, after which the apparatus 10 returns to sucking an underpressure in the package so that the package is completely emptied of pharmaceutical waste.
  • a liquid e.g. water and/or solvent, is fed into the package in order to remove a medicament from the package and/or in order to rinse the package so that no medicament residues remain in the emptied package.
  • the liquid to be removed from the package is conveyed through the channel system 9 to a selected receptacle 6a, 6b.
  • the liquid On its way to the receptacle 6a, 6b, the liquid may pass through a liquid counter 8, which shows the amount of the liquid in a desired unit of measurement.
  • a first emptying place 4a is connected to the receptacle 6a shown on the right in Figure 1 while other emptying places 4b to 4d, as also the suction tip 3 and the Luer connector 7, are correspondingly connected to the receptacle 6b on the left.
  • These connections may naturally also be implemented in another manner, particularly because the number of receptacles may also be other than two.
  • the receptacle 6a, 6b comprises pressure-proof caps or lids 14 provided with overfill detectors 15.
  • the overfill detector 15 prevents overfill of the receptacle 6a, 6b by closing a filling channel leading to the receptacle 6a, 6b.
  • the pressure cap or lid 4 is removed and replaced by a tight cap or lid which preferably comprises locking means for preventing the receptacle from being opened afterwards.
  • the pressure cap or lid 14 is placed on a new receptacle 6a, 6b, after which filling of the receptacle may begin.
  • the apparatus 10 may comprise a means 18 for opening a thin glass ampoule, enabling an unopened ampoule to be opened safely.
  • the means 18 comprises a slot or an opening enabling the neck of an ampoule to be cut by sideways rotation.
  • a user places the package to be emptied in a selected emptying place for the package and starts the emptying by using the push button or the like of the emptying place in question.
  • the contents of the package are sucked by underpressure for a determined period of time.
  • substitution air may be entered into the package for a certain period of time from the pressure accumulator 28 or the like, and/or rinsing liquid from the rinsing liquid reservoir 30.
  • an underpressure may be sucked into the package.
  • the package may be rinsed with a rinsing liquid.
  • the apparatus may be provided with a separate rinse button or the like.
  • the rins- ing phase takes place automatically without using a separate button or the like.
  • the rinsing liquid in the package is sucked by underpressure.
  • An alternative for implementing the above-described operations of the apparatus is to use time-controlled relays which control the magnetic valves.
  • FIGS 3A to 3C schematically show some details of the apparatus according to Figure 1.
  • Figure 3A shows an alternative embodiment of the third and the fourth emptying places 4c, 4d.
  • the structure of the emptying places 4c, 4d may be the same, except for the dimensioning: the third emptying place 4c is dimensioned for larger packaging bottles while the fourth emptying place 4d is for smaller packaging bottles.
  • the third and the fourth emptying places 4c, 4d comprise a drain tube 11, in this case a needle with a bevelled tip, and a filling tube 33 through which substitution air, overpressure and/or rinsing liquid may be fed into a packaging bottle 23.
  • the substance to be fed is determined according to the emptying program being used, automatically or through the user's control operations. It is to be noted that the filling tube 33 is not necessary and that e.g. all the mentioned feeding operations may also be implemented through the drain tube 11. It is further to be noted that the dimensions of the drain tube 11 and the filling tube 33 may differ from those shown in the figure.
  • the drain tube 1 is arranged at a bottom of a reception recess 21 so that it extends at a distance from the bottom of the reception recess 21.
  • the diameter of the reception recess 21 is dimensioned such that it enables a standard-sized packaging bottle 23 of a certain size to be arranged therein appropriately.
  • a mouth of the reception recess 21 may be provided with guiding means 22 which may form either an annular member around the reception recess 21 or, alternatively, with protrusions which are located separately and at a distance from one another around the reception recess 21.
  • the guiding means 22 guide the packaging bottle 23 in a correct position to the reception recess 21.
  • the guiding means 22 are made of polyamide or another appropriate plastic.
  • the guiding means 22 may be dimensioned to be more constricted than the reception recess 21 , in which case they guide packaging bottles 23 that are smaller in diameter than the aforementioned standard-sized packaging bottle 23.
  • the guiding means 22 may be removed from the mouth of the reception recess 21 e.g. when the packaging bottle 23 to be emptied is too large for the guiding means 22 in question.
  • the guiding means 22 are dimensioned so as to enable the packaging bottle 23, with the cap or lid 24 foremost, to be taken into the reception recess 21 in order for the drain tube 11 to penetrate the cap or lid 24.
  • the reception recess 21 may also be provided with second guiding means 27 for preventing contact of an object wider than the cap 24 with the drain tube 1 .
  • FIG. 3B shows an alternative embodiment of a second emptying place 4b.
  • the second emptying place 4b is provided for emptying thin glass ampoules in particular.
  • a thin glass ampoule may first be opened by an opening means 18, after which the opened end of the ampoule is taken into the reception recess 21 to enable the drain tube 1 to settle inside the ampoule.
  • the opened end of the ampoule may be loose with respect to the drain tube 11.
  • a medicament may flow into the conical reception recess 21 , wherefrom it may be sucked into a receptacle 6 through holes 28.
  • Thin glass ampoules may also be emptied using the suction tip 3, of course.
  • FIG 3C shows an alternative embodiment of the first emptying place 4a. This is primarily meant for emptying contrast medium syringes 26.
  • the drain tube 11 is arranged at the bottom of the conically narrowing reception recess 21.
  • An injection tip 26 of the contrast medium syringe 25 is arranged in the reception recess 21 , after which the contents of the syringe 25 are sucked into the receptacle 6.

Landscapes

  • Engineering & Computer Science (AREA)
  • Environmental & Geological Engineering (AREA)
  • Food Science & Technology (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne un procédé et un appareil de récupération de déchets pharmaceutiques liquides. Le procédé comprend l'agencement d'un emballage pharmaceutique à vider dans un élément de vidange (3, 4a à 4d, 7), l'agencement d'un tube de drainage (11) à travers un capuchon (24) de l'emballage pharmaceutique, la génération d'une pression négative ou d'une surpression dans l'emballage pharmaceutique de façon à vider l'emballage pharmaceutique d'un médicament, et le transport du médicament retiré de l'emballage pharmaceutique vers un réceptacle (6a, 6b).
PCT/FI2013/050845 2012-09-07 2013-09-03 Procédé et appareil de récupération de déchets pharmaceutiques liquides WO2014037613A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20125930 2012-09-07
FI20125930A FI124394B (fi) 2012-09-07 2012-09-07 Menetelmä ja laite nestemäisten lääkejätteiden talteen ottamiseksi

Publications (1)

Publication Number Publication Date
WO2014037613A1 true WO2014037613A1 (fr) 2014-03-13

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ID=50236584

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2013/050845 WO2014037613A1 (fr) 2012-09-07 2013-09-03 Procédé et appareil de récupération de déchets pharmaceutiques liquides

Country Status (2)

Country Link
FI (1) FI124394B (fr)
WO (1) WO2014037613A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105174172A (zh) * 2015-09-24 2015-12-23 天津市华宇农药有限公司 一种全自动直列式罐装机上的接料装置
CN105267037A (zh) * 2015-11-27 2016-01-27 曹耀锋 自动配药器

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5220947A (en) * 1990-08-20 1993-06-22 Cogema-Compagnie Generale Des Matieres Nucleaires Apparatus for emptying and rinsing non-recoverable flasks containing a toxic product
WO2004018295A2 (fr) * 2002-08-21 2004-03-04 Nord Jay D Procede et appareil d'elimination des dechets chirurgicaux liquides destines a proteger les travailleurs de la sante
WO2004098801A1 (fr) * 2003-05-08 2004-11-18 Sociedade Brasileira E Japonesa De Beneficência Santa Cruz Appareil et procede pour le nettoyage de catheters et d'autres dispositifs hemodynamiques
EP2100826A1 (fr) * 2006-12-06 2009-09-16 Xiao Liu Purificateur d'eaux usées médicales
US7896271B2 (en) * 2007-08-06 2011-03-01 Ann Wakeman Medication disposal system
CN201921126U (zh) * 2010-12-07 2011-08-10 湖南康都制药有限公司 混药接头
US8257336B2 (en) * 2006-02-16 2012-09-04 Roche Diagnostics International Ag System and device for removing pharmaceutical products

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5220947A (en) * 1990-08-20 1993-06-22 Cogema-Compagnie Generale Des Matieres Nucleaires Apparatus for emptying and rinsing non-recoverable flasks containing a toxic product
WO2004018295A2 (fr) * 2002-08-21 2004-03-04 Nord Jay D Procede et appareil d'elimination des dechets chirurgicaux liquides destines a proteger les travailleurs de la sante
WO2004098801A1 (fr) * 2003-05-08 2004-11-18 Sociedade Brasileira E Japonesa De Beneficência Santa Cruz Appareil et procede pour le nettoyage de catheters et d'autres dispositifs hemodynamiques
US8257336B2 (en) * 2006-02-16 2012-09-04 Roche Diagnostics International Ag System and device for removing pharmaceutical products
EP2100826A1 (fr) * 2006-12-06 2009-09-16 Xiao Liu Purificateur d'eaux usées médicales
US7896271B2 (en) * 2007-08-06 2011-03-01 Ann Wakeman Medication disposal system
CN201921126U (zh) * 2010-12-07 2011-08-10 湖南康都制药有限公司 混药接头

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105174172A (zh) * 2015-09-24 2015-12-23 天津市华宇农药有限公司 一种全自动直列式罐装机上的接料装置
CN105267037A (zh) * 2015-11-27 2016-01-27 曹耀锋 自动配药器

Also Published As

Publication number Publication date
FI20125930A (fi) 2014-03-08
FI124394B (fi) 2014-08-15

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