WO2014014852A1 - Composés en amas organométalliques fonctionnalisés - Google Patents

Composés en amas organométalliques fonctionnalisés Download PDF

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Publication number
WO2014014852A1
WO2014014852A1 PCT/US2013/050580 US2013050580W WO2014014852A1 WO 2014014852 A1 WO2014014852 A1 WO 2014014852A1 US 2013050580 W US2013050580 W US 2013050580W WO 2014014852 A1 WO2014014852 A1 WO 2014014852A1
Authority
WO
WIPO (PCT)
Prior art keywords
compound
reactive species
cluster
alkyne
nucleic acid
Prior art date
Application number
PCT/US2013/050580
Other languages
English (en)
Inventor
Chris R. MELVILLE
Miriam INBAR FESKE
Jill Lynden HERSCHLEB
Adam Matthew JOHNS
Kevin Lloyd Greenman
David PARTYKA
David ZALATAN
Dean F. TOSTE
Original Assignee
Melville Chris R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melville Chris R filed Critical Melville Chris R
Priority to PCT/US2013/050580 priority Critical patent/WO2014014852A1/fr
Publication of WO2014014852A1 publication Critical patent/WO2014014852A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/002—Osmium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0033—Iridium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)

Abstract

La présente invention concerne de petits amas organométalliques fonctionnalisés, des procédés de fabrication et de fonctionnalisation de ces composés et des applications pour leur utilisation.
PCT/US2013/050580 2012-07-16 2013-07-16 Composés en amas organométalliques fonctionnalisés WO2014014852A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2013/050580 WO2014014852A1 (fr) 2012-07-16 2013-07-16 Composés en amas organométalliques fonctionnalisés

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
USNONE 2006-12-21
PCT/US2013/050580 WO2014014852A1 (fr) 2012-07-16 2013-07-16 Composés en amas organométalliques fonctionnalisés

Publications (1)

Publication Number Publication Date
WO2014014852A1 true WO2014014852A1 (fr) 2014-01-23

Family

ID=49950111

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/050580 WO2014014852A1 (fr) 2012-07-16 2013-07-16 Composés en amas organométalliques fonctionnalisés

Country Status (1)

Country Link
WO (1) WO2014014852A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10758623B2 (en) 2013-12-09 2020-09-01 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008127197A1 (fr) * 2007-04-16 2008-10-23 National University Of Singapore Composé triangulo de métal et procédé d'utilisation de celui-ci

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008127197A1 (fr) * 2007-04-16 2008-10-23 National University Of Singapore Composé triangulo de métal et procédé d'utilisation de celui-ci

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COLANGELO, D. ET AL.: "Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme", JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 99, 2005, pages 505 - 512 *
HWU, J.R. ET AL.: "New trirutheium clusters as photoinduced DNA-binding and cleabing agents", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 75, no. 5, 2002, pages 457 - 461 *
YOSHIMURA, T. ET AL.: "Direct observation of a {Re6( u 3-S)8} core-to-ligand charge-transfer excited state in an octahedral hexarhenium complex", INORGANIC CHEMISTRY, vol. 50, 2011, pages 9918 - 9920 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10758623B2 (en) 2013-12-09 2020-09-01 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US11529420B2 (en) 2013-12-09 2022-12-20 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same

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