WO2014006754A1 - Appareil d'administration de liquide - Google Patents

Appareil d'administration de liquide Download PDF

Info

Publication number
WO2014006754A1
WO2014006754A1 PCT/JP2012/067371 JP2012067371W WO2014006754A1 WO 2014006754 A1 WO2014006754 A1 WO 2014006754A1 JP 2012067371 W JP2012067371 W JP 2012067371W WO 2014006754 A1 WO2014006754 A1 WO 2014006754A1
Authority
WO
WIPO (PCT)
Prior art keywords
state
plunger
cover member
puncture
liquid
Prior art date
Application number
PCT/JP2012/067371
Other languages
English (en)
Japanese (ja)
Inventor
正臣 今井
滋晃 冨家
学 有延
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to PCT/JP2012/067371 priority Critical patent/WO2014006754A1/fr
Priority to JP2014523535A priority patent/JP5897125B2/ja
Publication of WO2014006754A1 publication Critical patent/WO2014006754A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion

Definitions

  • the present invention relates to a liquid administration device.
  • the syringe is generally composed of an outer cylinder, a gasket that can slide within the outer cylinder, and a pusher (plunger) that moves the gasket.
  • a pusher plunger
  • Such a syringe is configured to move the gasket toward the distal end side by pushing the pusher into the outer cylinder, thereby injecting the chemical liquid stored in the outer cylinder from the needle body to the object (for example, see Patent Document 1).
  • An object of the present invention is to provide a liquid administration device that is excellent in operability and can prevent liquid leakage.
  • a cylindrical body having a bottomed cylinder with a bottom at the tip and filled with liquid inside;
  • a needle tube having a sharp distal tip at the distal end and at the distal end of the proximal end, provided on the distal end side of the cylindrical body, and capable of communicating with the cylindrical body;
  • a gasket that can slide in the cylinder;
  • An operation member that performs a pressing operation of pressing the gasket toward a distal direction to discharge the liquid from the needle tube, the first plunger unit coupled to a proximal end side of the gasket, and the first An operating member having a second plunger portion disposed on the proximal end side of the plunger portion; Lock means for maintaining a positional relationship between the first plunger portion and the second plunger portion;
  • the operation member has a first state in which the gasket is pressed to a movement limit where the gasket is in contact with the bottom portion while the positional relationship is maintained by the locking means, and the positional relationship from the first state.
  • the liquid administration device
  • One plunger of the first plunger portion and the second plunger portion has at least two plate pieces arranged around the central axis of the cylindrical body, and the other plunger is In contact with the ends of the plate pieces in the first state, and in the second state, the plate pieces are deformed in a direction to be separated from each other and spread out while entering between the plate pieces.
  • the liquid administration device according to the above (2) which has a rod-like body.
  • the lock means has a tubular regulating portion disposed concentrically with the cylinder inside the cylinder, Each said board piece is inserted in the said control part in the said 1st state, deformation
  • a puncture prevention position that covers at least the tip side needle tip of the needle tube and prevents puncture by the tip side needle tip, and retracts from the puncture prevention position in the proximal direction so that the tip side needle tip is A cover member that is exposed and movable to a puncture position that allows puncture with the tip side needle tip;
  • the liquid administration device according to any one of (1) to (4), further comprising a biasing member that biases the cover member in a direction from the puncture position toward the puncture prevention position.
  • the cover member is retracted to the puncture position, the operation member is changed from the first state to the second state, and the cover member is moved to the puncture prevention position.
  • the cover member has a cylindrical shape and is disposed on the outer peripheral side of the cylindrical body
  • the restricting means includes at least one elastic piece provided on one of the outer peripheral side of the cylindrical body and the inner peripheral side of the cover member, and an engagement provided on the other, with which the elastic piece can be engaged.
  • a pressing portion that presses the elastic piece in a direction of engaging the engaging portion against its own elastic force
  • the elastic piece is provided to be inclined with respect to the central axis on the inner peripheral side of the cover member,
  • the engaging portion is provided on the outer peripheral side of the cylindrical body,
  • the pressing portion is disposed between the outer peripheral portion of the cylindrical body and the inner peripheral portion of the cover member on the proximal end side with respect to the elastic piece, the cover member is retracted to the puncture position, and the operation member Is composed of a coil spring that is maintained in a compressed state from the first state to the second state
  • the restricting means is provided on the operation member, the coil member in the compressed state when the cover member is retracted to the puncture position and the operation member is changed from the first state to the second state.
  • a release part for releasing The coil spring is configured such that when the compression state is released by the release portion, the elastic piece is pressed and tilted from the base end side to engage the elastic piece with the engagement portion (8)
  • a liquid administration device according to 1.
  • a support member that supports the needle tube movably along the central axis direction with respect to the cylindrical body,
  • the cylindrical body has a mouth portion formed in the bottom portion, through which the liquid passes, and a sealing portion made of an elastic material for sealing the mouth portion in a liquid-tight manner
  • the needle tube is composed of a double-ended needle further having a sharp proximal end needle tip at the proximal end, and communicates with the cylindrical body when the proximal needle tip penetrates the sealing portion.
  • the proximal needle tip is separated from the sealing portion when the cover member is in the puncture prevention position, and the cover member is moved to the puncture position by operation of the operation member.
  • the liquid administration device according to any one of (1) to (9), wherein the cover member moves together with the support member along the needle tube in the proximal direction, and pierces the sealing portion.
  • FIG. 1 is a longitudinal cross-sectional view sequentially illustrating an operating state when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 2 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 3 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 4 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 5 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 1 is a longitudinal cross-sectional view sequentially illustrating an operating state when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 2 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 6 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 7 is a longitudinal cross-sectional view sequentially illustrating operating states when the liquid administration device (first embodiment) of the present invention is used.
  • FIG. 8 is an exploded perspective view of the main part of the liquid administration device (first embodiment) of the present invention.
  • FIG. 9 is a longitudinal sectional perspective view showing the cover member in FIG. 8.
  • FIG. 10 is a longitudinal sectional view of the liquid administration device in the state shown in FIG. 7 when the angle is changed by 45 degrees around the axis.
  • FIG. 11 is a longitudinal cross-sectional view which shows the operation state at the time of use of the liquid administration device (2nd Embodiment) of this invention in order.
  • FIG. 11 is a longitudinal cross-sectional view which shows the operation state at the time of use of the liquid administration device (2nd Embodiment) of this invention in order.
  • FIG. 12 is a longitudinal cross-sectional view sequentially illustrating the operating state during use of the liquid administration device (second embodiment) of the present invention.
  • FIG. 13 is a longitudinal cross-sectional view which shows the operation state at the time of use of the liquid administration device (3rd Embodiment) of this invention in order.
  • FIG. 14 is a longitudinal cross-sectional view sequentially illustrating the operating state when the liquid administration device (third embodiment) of the present invention is used.
  • liquid administration device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
  • FIGS. 1 to 7 are longitudinal sectional views sequentially showing operating states of the liquid administration device of the present invention (first embodiment), and FIG. 8 is a liquid administration device of the present invention (first embodiment).
  • 9 is an exploded perspective view of the main part of FIG. 9, FIG. 9 is a perspective view of a vertical cross section of the cover member in FIG. 8, and FIG. 10 is a state in which the liquid administration device in the state shown in FIG. It is a longitudinal cross-sectional view when seen.
  • the upper side in FIGS. 1 to 10 is referred to as “base end” or “upper (upper)”, and the lower side is referred to as “tip” or “lower (lower)”.
  • a liquid administration device 10 shown in FIGS. 1 to 7 is a medical instrument used when a liquid Q is administered (injected) to a living body B.
  • the liquid Q is appropriately selected according to the purpose of use.
  • hematopoietic agents, vaccines, hormone preparations, antirheumatic agents, anticancer agents, anesthetics, blood coagulation inhibitors, etc. Chemicals to be used.
  • the liquid administration device 10 includes an inner cylinder (cylinder) 1, a lock member (lock means) 40 fixed to the proximal end of the inner cylinder 1, a double-ended needle 2 and a support member 9, and a puncture needle 50.
  • a gasket 3 that can slide in the inner cylinder 1, an operation member 11 that performs a pressing operation to press the gasket toward the distal end, a cover member 6 that is disposed on the outer peripheral side of the inner cylinder 1, and a cover member 6 is provided with a coil spring 60 as an urging member for urging 6 and a regulating means 30 capable of regulating the movement of the cover member 6.
  • the inner cylinder 1 is a member provided with a bottom portion 12 and a side wall 13 erected from the edge of the bottom portion 12 at the tip, that is, a bottomed cylindrical shape It has the inner cylinder main body 14 comprised with the member which makes
  • the inner cylinder 1 can be filled with the liquid Q.
  • the bottom portion 12 has a disc shape, and a mouth portion 121 through which the liquid Q passes is formed through the center portion thereof.
  • the side wall 13 has a cylindrical shape.
  • a flange portion 132 having an enlarged inner diameter protrudes from the outer peripheral portion of the base end of the side wall 13.
  • the inner cylinder 1 has a sealing member (sealing part) 15 for liquid-tightly sealing the mouth part 121 of the inner cylinder main body 14 and a fixing member 16 for fixing the sealing member 15 from the distal end side. is doing.
  • the sealing member 15 is composed of a disk-shaped elastic piece, and a recess 151 is formed on the base end surface thereof.
  • a ring-shaped convex portion 122 protruding from the mouth portion 121 of the inner cylinder main body 14 can be fitted into the concave portion 151 in a liquid-tight manner.
  • the sealing member 15 can be mounted on the mouth portion 121 of the inner cylinder main body 14 and the mouth portion 121 can be sealed in a liquid-tight manner.
  • the fixing member 16 is a ring-shaped member.
  • the fixing member 16 is fitted to the sealing member 15 from the outer peripheral side, and the sealing member 15 is sandwiched between the fixing member 16 and the convex portion 122, whereby the sealing member 15 is attached to the inner cylinder main body 14. It can be securely fixed. Thereby, the detachment
  • a fixing method of the fixing member 16 a method by adhesion or a method by welding may be used as a fixing method of the fixing member 16.
  • polyvinyl chloride polyethylene, a polypropylene, cyclic polyolefin, Polystyrene such as polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, nylon) 6, various types of resins such as nylon 6,6, nylon 6,10, nylon 12).
  • polypropylene, cyclic polyolefin, polyester, poly- (4-methyl) are easy to mold. Penten-1) Such resins are preferred.
  • the elastic material constituting the sealing member 15 and the gasket 3 is not particularly limited.
  • various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber
  • elastic materials such as various thermoplastic elastomers such as polyurethane, polyester, polyamide, olefin, and styrene, and mixtures thereof.
  • a puncture needle 50 is disposed on the distal end side of the inner cylinder 1.
  • the puncture needle 50 is composed of a double-ended needle 2 and a support member 9.
  • the double-ended needle 2 is a hollow needle tube and has a sharp distal needle tip 21 at the distal end and a sharp proximal needle tip 23 at the proximal end.
  • the double-ended needle 2 can puncture the living body B with the distal needle tip 21 and can pierce the sealing member 15 of the inner cylinder 1 with the proximal needle tip 23.
  • the lumen portion (hollow portion) of the double-ended needle 2 communicates with the inner cylinder 1 in a state where the proximal needle tip 23 penetrates the sealing member 15 of the inner cylinder 1, and the liquid from the inner cylinder 1 It functions as a flow path 22 through which Q passes. Further, the liquid Q is injected into the living body B through the flow path 22 in a state where the living body B is punctured from the skin to a predetermined depth with the tip side needle tip 21.
  • constituent material of the double-ended needle 2 is not particularly limited, and examples thereof include a metal material such as stainless steel, aluminum or aluminum alloy, titanium or titanium alloy.
  • the double-ended needle 2 having such a configuration is attached to the inner cylinder 1 via the support member 9.
  • the support member 9 supports the double-ended needle 2 so as to be movable along the central axis direction with respect to the inner cylinder 1.
  • the support member 9 includes a fixed portion (support portion) 91 having a disk shape and a wall portion 92 erected from the edge of the fixed portion 91 toward the proximal direction.
  • the fixing portion 91 can support and fix the double-ended needle 2 at the center thereof.
  • fixed part 91 of the double-ended needle 2 is a way of the longitudinal direction of the double-ended needle 2.
  • the wall portion 92 has a cylindrical shape, and a plurality of grooves (slits) 922 are formed along the axial direction thereof. These grooves 922 are arranged at equal intervals along the circumferential direction of the wall portion 92. In each of the grooves 922, a protrusion 123 formed so as to protrude outward from the bottom 12 of the inner cylinder 1 is inserted. Thereby, when the puncture needle 50 moves, the puncture needle 50 is guided, and thus the movement is performed smoothly.
  • the puncture needle 50 moves, so that the proximal end needle tip 23 is separated from the sealing member 15 of the inner cylinder 1, and the proximal end needle tip 23 is sealed.
  • the piercing state shown in FIG. 4 to FIG. 7 and FIG. Thereby, the unintentional leakage of the liquid Q from the double-ended needle 2 is prevented until it reaches the piercing state.
  • the gasket 3 is accommodated so as to be slidable along the axial direction of the inner cylinder 1.
  • the space surrounded by the gasket 3 and the inner cylinder 1 is filled with the liquid Q in advance. And when the gasket 3 moves toward the front-end
  • This gasket 3 has a cylindrical outer shape, and two projecting portions 31 and 32 project from the outer peripheral portion thereof.
  • the protrusion 31 and the protrusion 32 are separated along the axial direction of the gasket 3.
  • each of the protrusions 31 and 32 has a ring shape along the circumferential direction of the gasket 3, and its outer diameter is slightly larger than the inner diameter of the inner cylinder 1 in a natural state where no external force is applied. Thereby, each of the protrusions 31 and 32 can slide while being in close contact with the inner peripheral portion 133 of the side wall 13 of the inner cylinder 1. Can be improved.
  • the gasket 3 having such a configuration is pressed by the operation member 11.
  • the liquid Q can be discharged from the double-ended needle 2 by this pressing operation.
  • the operation member 11 is an assembly in which two parts are assembled and fixed.
  • the operating member 11 has a first plunger portion 7 and a second plunger portion 8 which are configured separately from each other.
  • the operating member 11 can take the first state shown in FIGS. 2 to 5 and the second state shown in FIGS.
  • the maintenance of the positional relationship between the first plunger portion 7 and the second plunger portion 8 is released from the first state, and the second plunger portion 8 is in relation to the first plunger portion 7. It is in the state which moved toward the tip direction.
  • the operation member 11 further includes a grip member 20 that is gripped when the operation member 11 is operated.
  • a grip member 20 that is gripped when the operation member 11 is operated.
  • the first plunger portion 7 (one plunger) includes a connecting portion 71 connected to the gasket, four plate pieces 72 provided on the base end side of the connecting portion 71, and the connecting portion 71 and the four plates.
  • a flange portion 73 provided between the two pieces 72 and a columnar portion 74 surrounded by four plate pieces 72 are provided.
  • the connecting portion 71 can be inserted into and fitted into the concave portion 33 opened in the base end surface of the gasket 3. As a result, the first plunger portion 7 is connected to the proximal end side of the gasket 3.
  • the flange portion 73 has a disk shape and is in contact with the proximal end surface of the gasket 3.
  • the four plate pieces 72 are formed so as to protrude from the flange portion 73 toward the proximal direction. These plate pieces 72 are arranged at equiangular intervals around the central axis of the liquid administration device 10 (inner cylinder 1). The adjacent plate pieces 72 are preferably separated from each other.
  • each plate piece 72 an inclined surface 721 inclined with respect to the central axis is formed at an inner portion thereof.
  • the number of the plate pieces 72 is four in the present embodiment, but is not limited thereto, and may be two, three, five or more, for example.
  • a columnar portion 74 having a columnar shape is formed on the inner side of the four plate pieces 72 arranged around the central axis so as to protrude from the flange portion 73 toward the proximal direction. Further, the overall length of the columnar portion 74 is shorter than the overall length of the plate piece 72.
  • This columnar portion 74 regulates its access limit when the second plunger portion 8 arranged on the proximal end side of the first plunger portion 7 moves toward the first plunger portion 7 and approaches it. It functions as a restricting section (see FIGS. 6 and 7).
  • the second plunger portion 8 (the other plunger) includes a top plate 81 having a disk shape, and a first spreading portion (rod-like body) formed to protrude from the lower surface of the top plate 81. 82, two second spreading parts 83, two first claw parts 84, and two second claw parts 85.
  • the first spreading portion 82 protrudes in a prismatic shape from the center portion of the top plate 81 toward the distal end.
  • a tapered portion 821 having an outer diameter that gradually decreases toward the distal end is formed at the distal end of the first spreading portion 82.
  • the first spreading portion 82 has an inclined surface 721 (end portion) of each plate piece 72 of the taper portion 821 of the first plunger portion 7. Abut. Thereby, the gasket 3 can be pressed to the movement limit together with the first plunger portion 7.
  • the taper angle of the taper part 821 and the inclination angle of the inclined surface 721 are the same.
  • the 1st expansion part 82 (1st plunger part 7) and each plate piece 72 (2nd plunger part 8) are spaced apart.
  • the first spreading portion 82 has the taper portion 821 exceeding the inclined surface 721 of each plate piece 72 of the first plunger portion 7.
  • the plate pieces 72 are inserted between the plate pieces 72 while being deformed and spread apart in a direction away from each other. Thereby, the 2nd plunger part 8 can move toward the front-end
  • the two second spreading portions 83 protrude in a columnar shape from the top plate 81 toward the tip. These second spreading parts 83 are arranged to face each other via the first spreading part 82. Moreover, these 2nd expansion parts 83 function as a releasing part which releases the coil spring 70 of the compression state which the control means 30 has, so that it may mention later (refer FIG. 6, FIG. 7).
  • the two first claw portions 84 are formed from the top plate 81 toward the front end, and are disposed to face each other via the first spreading portion 82. Note that the two first claw portions 84 and the two second claw portions 85 are arranged at positions that are different from each other by 90 degrees with the first spreading portion 82 as the center. Further, these first claw portions 84 can be engaged with the lock member 40 (engagement hole 405) when the operation member 11 is in the second state. By this engagement, it is possible to prevent the operation member 11 from moving again in the proximal direction and being in a state where a pressing operation can be performed.
  • the two second claw portions 85 are also formed from the top plate 81 toward the distal end, and are arranged to face each other via the first spreading portion 82. Each of the second claw portions 85 is disposed outside the second pushing and spreading portion 83.
  • the gripping member 20 has a cylindrical shape, and its inner peripheral portion 201 is engaged with each second claw portion 85 (see FIGS. 1 to 7). By this engagement, the second plunger portion 8 and the gripping member 20 are fixed to each other. Then, when operating the operation member 11, for example, the index finger to the little finger of one hand is hung on the outer peripheral portion 202 of the gripping member 20, and the thumb is hung on the top plate 81 of the second plunger portion 8 to perform the operation. It can be done reliably.
  • a lock member 40 is fixed to the proximal end portion of the inner cylinder 1.
  • the lock member 40 is a member that can maintain the positional relationship between the first plunger portion 7 and the second plunger portion 8 in the first state.
  • the lock member 40 has a disk-shaped top plate 401, a tubular regulating portion 402 penetrating through the center of the top plate 401, and an edge of the top plate 401 toward the distal end. And two elastic pieces 403 formed to protrude.
  • the top plate 401 is in contact with the flange portion 132 of the inner cylinder 1 from the base end side and is fitted (fixed).
  • the fixing method is not particularly limited, and examples thereof include a method using adhesion (adhesion using an adhesive or a solvent), a method using fusion (thermal fusion, high frequency fusion, ultrasonic fusion, etc.), and the like.
  • top plate 401 is formed with insertion holes 404 through which the respective second expanding portions 83 are inserted when the second plunger portion 8 moves in the distal direction.
  • top plate 401 is formed with engagement holes 405 for engaging the respective first claw portions 84 when the second plunger portion 8 moves in the distal direction.
  • the regulating part 402 is formed integrally with the top plate 401 and is disposed concentrically with the inner cylinder 1 inside the inner cylinder 1. As shown in FIGS. 1 to 4, four plate pieces 72 of the first plunger portion 7 are collectively inserted into the restricting portion 402, and deformation of each plate piece 72 to the outside is restricted. The Thereby, in the first state, the first spreading portion 82 of the second plunger portion 8 is reliably prevented from entering between the plate pieces 72, and thus the first plunger portion 7 and the second plunger portion 8 are prevented from entering each other.
  • the gasket 3 can be pressed to the movement limit while maintaining the positional relationship with the plunger portion 8.
  • the four plate pieces 72 inserted in the restricting portion 402 are moved to the first end portion 82 of the second plunger portion 8 moved in the proximal direction. Is pushed out of the restricting portion, and the restriction by the restricting portion 402 is released, so that outward deformation is possible.
  • the 1st expansion part 82 of the 2nd plunger part 8 can change each board piece 72 outside, respectively, and can enter between each board piece 72, Therefore
  • the second plunger portion 8 can move in the distal direction with respect to the first plunger portion 7.
  • the two elastic pieces 403 are formed integrally with the top plate 401 and are disposed to face each other with the restricting portion 402 interposed therebetween.
  • the number of elastic pieces 403 is two in this embodiment, but is not limited to this, and may be three or more, for example.
  • each elastic piece 403 is bent inward, and the tip of the bent portion 407 is a protruding piece 406. As shown in FIGS. 1 to 5, the coil spring 70 can be maintained in a compressed state between the projecting piece 406 of each elastic piece 403 and the top plate 401.
  • an inclined portion 408 that is inclined with respect to the central axis of the liquid administration device 10 is formed in the bent portion 407. As shown in FIGS. 6 and 7, the inclined portion 408 is pressed by the second spreading portion 83 of the second plunger portion 8. As a result, the elastic piece 403 is elastically deformed outward, so that the protruding piece 406 can be detached from the coil spring 70 to release the coil spring 70 in the compressed state, that is, in the compressed state.
  • the coil spring 70 extends.
  • a cylindrical cover member 6 is disposed concentrically with the inner cylinder 1 on the outer peripheral side of the inner cylinder 1. Similar to the puncture needle 50, the cover member 6 is supported so as to be movable along the axial direction with respect to the inner cylinder 1. Thereby, the cover member 6 can move between the puncture prevention position shown in FIGS. 1, 2 and 7 (FIG. 10) and the puncture position shown in FIGS. In the puncture prevention position, at least the tip side needle tip 21 of the double-ended needle 2 can be covered, and thus puncture by the tip side needle tip 21 is prevented. In addition, the tip side needle tip 21 is also prevented from being damaged. At the puncture position retracted in the proximal direction from the puncture prevention position, the distal needle tip 21 is exposed, and puncture by the distal needle tip 21 becomes possible.
  • the puncture needle 50 described above is in a state in which the proximal end needle tip 23 is separated from the sealing member 15 of the inner cylinder 1 when the cover member 6 is in the puncture prevention position. Further, when the cover member 6 comes to the puncture position, the puncture needle 50 pushes and moves the puncture needle 50 (the double-ended needle 2 together with the support member 9) toward the proximal end. The proximal needle tip 23 is pierced through the sealing member 15.
  • the cover member 6 includes a cylindrical outer cylinder part 61, a cylindrical inner cylinder part 62 concentrically arranged with the outer cylinder part 61, and a connection that connects the outer cylinder part 61 and the inner cylinder part 62. Part 63.
  • the outer cylinder portion 61 can cover most of the inner structure 80 formed by assembling the inner cylinder 1, the lock member 40, the puncture needle 50, and the gasket 3.
  • the inner cylinder part 62 is a part having a shorter overall length than the outer cylinder part 61, and has a plate-like tip wall part 621 at the tip part.
  • the distal end wall portion 621 can contact the support member 9 from the distal end side and press the support member 9 toward the proximal direction.
  • the double-ended needle 2 moves together with the support member 9 in the proximal direction, so that the proximal needle tip 23 can pierce the sealing member 15 (see FIGS. 3 and 4). .
  • an opening 622 that penetrates the central portion is formed in the central portion of the tip wall portion 621. As shown in FIGS. 3 to 6, when the cover member 6 is in the puncture position, the distal end side needle tip 21 of the puncture needle 50 protrudes (exposes) from the opening 622.
  • the connecting portion 63 connects the tip portions of the outer cylinder portion 61 and the inner cylinder portion 62 and is a ring-shaped portion.
  • the cover member 6 having such a configuration is urged by the coil spring 60 in a direction from the puncture position to the puncture prevention position.
  • the coil spring 60 has a distal end 601 in contact with the connecting portion 63 of the cover member 6 and a proximal end 602 in contact with the top plate 81 of the second plunger portion 8 of the operation member 11. Between these, the coil spring 60 is compressed. Thereby, the cover member 6 can be reliably urged in the direction from the puncture position to the puncture prevention position.
  • the cover member 6 can be positioned at the puncture prevention position until the liquid administration device 10 is used and after it is used, so that erroneous puncture by the distal needle tip 21 is prevented. It can be surely prevented.
  • the constituent material of the coil spring 60 is not particularly limited, and for example, a metal material such as stainless steel can be used.
  • the movement of the cover member 6 is regulated by the regulation means 30.
  • the restricting means 30 moves the cover member 6 to the puncture position again after the cover member 6 is temporarily retracted to the puncture position and the operation member 11 is changed from the first state to the second state and returned to the puncture prevention position. Is to regulate.
  • the restricting means 30 includes four elastic pieces 64 provided on the inner peripheral side of the cover member 6, that is, on the base end portion of the inner cylinder portion 62 constituting the cover member 6. , An outer peripheral side of the inner cylinder 1, that is, an outer peripheral portion of the inner cylinder main body 14, and an engaging portion 141 that can engage each elastic piece 64, and each elastic piece 64 engage with the engaging portion 141.
  • a coil spring 70 is provided as a pressing portion that collectively presses in the direction.
  • Each elastic piece 64 is integrally formed so as to project from the proximal end portion of the inner cylindrical portion 62 toward the proximal direction, and is inclined inward with respect to the central axis of the inner cylindrical portion 62 (liquid administration device 10). ing.
  • the elastic pieces 64 are arranged at equiangular intervals around the central axis of the inner cylindrical portion 62.
  • Each elastic piece 64 provided in this manner is further tilted inward by the biasing force of the coil spring 70 (see FIG. 6). Then, each of the further inclined elastic pieces 64 is engaged with the engaging portion 141, and the movement of the cover member 6 to the puncture position again is restricted (see FIG. 10).
  • the number of elastic pieces installed is four in this embodiment, but is not limited to this, and may be one, two, three, or five or more, for example.
  • the engaging portion 141 is configured by a groove formed in the outer peripheral portion of the inner cylinder main body 14 along the circumferential direction. The base end portion of each elastic piece 64 can be engaged with the engaging portion 141 formed in this way.
  • the coil spring 70 is disposed closer to the base end side than the elastic piece 64 between the outer peripheral portion of the inner cylinder main body 14 and the inner peripheral portion of the outer cylinder portion 61 of the cover member 6.
  • it does not specifically limit as a constituent material of the coil spring 70,
  • the same constituent material as the coil spring 60 can be used.
  • the coil spring 70 includes the top plate 401 of the lock member 40 and the projecting pieces 406 of the elastic pieces 403 projecting from the top plate 401 until the liquid Q is completely discharged. In between, it is maintained in a compressed state.
  • the coil spring 70 causes each second spreading portion 83 to spread the elastic piece 403 of the lock member 40 outward, thereby It is released from the compressed state and expands.
  • the extended coil spring 70 can be engaged with the engaging portion 141 by pressing and tilting each elastic piece 64 collectively from its proximal end side (see FIG. 10). Due to this engagement, the movement of the cover member 6 to the puncture position again is restricted, and thus it is possible to reliably prevent erroneous puncture by the tip side needle tip 21 and damage to the tip side needle tip 21. .
  • the second spreading portion 83 that functions as a release portion that releases the coil spring 70 in a compressed state also constitutes a part of the regulating means 30.
  • a liquid administration device 10 in an unused state is prepared.
  • the cover member 6 is in the puncture prevention position and covers the tip side needle tip 21 of the double-ended needle 2.
  • the cover member 6 can remain at the puncture prevention position by the urging force of the coil spring 60, and the state where the tip side needle tip 21 is covered with the cover member 6 is maintained. Thereby, the erroneous puncture by the tip side needle tip 21 can be prevented reliably.
  • the proximal end needle tip 23 of the double-ended needle 2 is separated from the sealing member 15 of the inner cylinder 1, and the sealing member 15 is not yet pierced. Thereby, the aseptic state of the liquid Q can be maintained until the administration of the liquid Q is started.
  • each plate piece 72 of the first plunger portion 7 and the first spreading portion 82 of the second plunger portion 8 are separated from each other, and the separated state is a biasing force of the coil spring 60. Is maintained by
  • the coil spring 70 constituting the restricting means 30 is in a compressed state between the top plate 401 of the lock member 40 and the protruding piece 406 of each elastic piece 403.
  • a method for setting such a magnitude relationship between the forces is not particularly limited. For example, a method of appropriately selecting the constituent materials of the gasket 3 and the inner cylinder main body 14 and adjusting the frictional force generated between these members. A method of adjusting the biasing force of the coil spring 60 by appropriately selecting a constituent material of the coil spring 60, a method of combining these adjustment methods, and the like can be given.
  • each plate piece 72 of the first plunger portion 7 is inserted into the restricting portion 402 of the lock member 40 and the deformation to the outside is restricted. Thereby, it is prevented that each plate piece 72 of the first plunger part 7 is spread outward by the first spreading part 82 of the second plunger part 8. The positional relationship with the second plunger portion 8 is maintained.
  • each plate piece 72 of the first plunger portion 7 comes out of the restriction portion 402 of the lock member 40 and the restriction by the restriction portion 402 is released.
  • the liquid administration device 10 is suitable, for example, when administering an expensive liquid Q or when administering a liquid Q whose dose is strictly determined.
  • the liquid administration device 10 in the former case, it is not necessary to store a little extra with respect to the dose assuming liquid leakage, and therefore the price of the liquid administration device 10 can be suppressed as much as possible. In the latter case, since the liquid leakage can be prevented, the dose can be strictly controlled.
  • each second spreading portion 83 of the second plunger portion 8 pushes the elastic piece 403 of the lock member 40 outward against its own elastic force.
  • the coil spring 70 is released from the compressed state and presses each elastic piece 64 disposed on the cover member 6.
  • each elastic piece 64 tilts inward, but cannot yet engage with the engaging portion 141 provided in the inner cylinder 1.
  • engagement with each elastic piece 64 and the engaging part 141 is performed when the cover member 6 returns to the puncture prevention position by the next operation.
  • liquid administration device 10 having the above-described configuration, a series of operations from puncture to administration is performed with one action of holding the operation member 11 and pressing the operation member 11 as it is until the movement of the operation member 11 stops. Can be performed accurately and reliably, and the operability is excellent.
  • the cap 90 may be attached to the liquid administration device 10 after the operation [7] (see FIG. 7).
  • the cap 90 has a bottomed cylindrical shape, and the inner peripheral portion thereof can be fitted or engaged with the outer peripheral portion of the distal end of the gripping member 20 of the operation member 11, for example. This reliably prevents the cap 90 mounted on the liquid administration device 10 from being detached.
  • the cap 90 can prevent, for example, blood adhering to the distal needle tip 21 from being scattered outside.
  • FIG. 11 and FIG. 12 are longitudinal sectional views sequentially showing the operating state when the liquid administration device of the present invention (second embodiment) is used.
  • This embodiment is the same as the first embodiment except that the configuration of the operation member is different.
  • the operation member 11A of the liquid administration device 10 of the present embodiment has a first plunger portion 7A and a second plunger portion 8A.
  • the gasket 3 is pressed to the movement limit where the gasket 3 abuts against the bottom 12 of the inner cylinder 1 while the positional relationship between the first plunger portion 7A and the second plunger portion 8A is maintained.
  • the maintenance of the positional relationship between the first plunger portion 7A and the second plunger portion 8A is released from the first state and the first state, so that the second plunger portion 8A is in relation to the first plunger portion 7A.
  • the second state (see FIG. 12) moved toward the distal end direction can be taken.
  • the first plunger portion 7 ⁇ / b> A includes a connecting portion 71, a columnar portion 75 provided on the proximal end side of the connecting portion 71, and a flange portion 73 provided between the connecting portion 71 and the columnar portion 75. ing.
  • the columnar portion 75 is a portion formed to protrude in a cylindrical shape toward the proximal direction.
  • the outer diameter of the columnar portion 75 is constant along the central axis direction of the columnar portion 75. Further, the base end surface 751 of the columnar portion 75 is inclined with respect to the central axis.
  • the second plunger portion 8A includes a top plate 81, a pressing portion 86 formed to project from the lower surface of the top plate 81, two second widening portions 83, two first claw portions 84, and two first 2 claw portions 85.
  • the pressing portion 86 is a portion that presses the columnar portion 75 of the first plunger portion 7A and tilts the columnar portion 75 (see FIG. 12).
  • the pressing portion 86 is formed so as to protrude in a cylindrical shape toward the distal end direction.
  • the outer diameter of the pressing portion 86 is constant along the central axis direction of the pressing portion 86.
  • the distal end surface 861 of the pressing portion 86 is inclined in the same direction as the proximal end surface 751 of the columnar portion 75 in a state before being inclined.
  • the operation member 11A when the operation member 11A is pressed from the unused state shown in FIG. 11, the operation member 11A enters the first state.
  • the distal end surface 861 of the pressing portion 86 of the second plunger portion 8A contacts the proximal end surface 751 of the columnar portion 75 of the first plunger portion 7A in the restricting portion 402. Thereby, the gasket 3 can be pressed to the movement limit together with the first plunger portion 7A.
  • the base end surface 751 of the columnar portion 75 slides in the inclination direction with respect to the distal end surface 861 of the pressing portion 86, and as a result, the columnar portion 75 tilts.
  • the 2nd plunger part 8A can move toward the direction of a tip to the 1st plunger part 7A. Therefore, similarly to the first embodiment, the operation of pushing the operating member 11A can be continued even after the administration of the liquid Q is completed, and the residual pressure in the inner cylinder 1 is reliably removed during that time. At the same time, the liquid Q surely penetrates into the living body B.
  • FIG. 13 and FIG. 14 are longitudinal sectional views sequentially showing the operating state when the liquid administration device (third embodiment) of the present invention is used.
  • This embodiment is the same as the first embodiment except that the configuration of the operation member is different.
  • the operation member 11B of the liquid administration device 10 of the present embodiment includes a first plunger portion 7B, a second plunger portion 8B, a first plunger portion 7B, and a second plunger portion. It has the connection part 111 which connects the plunger part 8B. Even in this operation member 11B, the gasket 3 is pressed to the movement limit where the gasket 3 abuts against the bottom portion 12 of the inner cylinder 1 while the positional relationship between the first plunger portion 7B and the second plunger portion 8B is maintained.
  • the maintenance of the positional relationship between the first plunger portion 7B and the second plunger portion 8B is released from the first state and the first state, so that the second plunger portion 8B is in relation to the first plunger portion 7B.
  • the second state (see FIG. 14) moved toward the distal end direction can be taken.
  • the first plunger portion 7 ⁇ / b> B has a connecting portion 71 and a flange portion 73.
  • the second plunger portion 8B includes a top plate 81, a columnar portion 87 formed in a columnar shape on the lower surface of the top plate 81, two second spreading portions 83, and two first claw portions 84 and 2. Two second claws 85.
  • the connecting portion 111 connects the flange portion 73 of the first plunger portion 7B and the columnar portion 87 of the second plunger portion 8B, and includes a plurality of easily deformable portions 112 made of plate pieces (this embodiment) 4 in the form). Each easily deformable portion 112 is arranged at equal intervals around the central axis of the operation member 11B.
  • the operation member 11B In the unused state shown in FIG. 13, the operation member 11B is in the first state. In this first state, each easily deformable portion 112 is located in the restricting portion 402, and deformation is restricted. Thereby, the positional relationship of the 1st plunger part 7B and the 2nd plunger part 8B is maintained, Therefore The gasket 3 can be pressed to a movement limit.
  • each easily deformable portion 112 comes out of the restricting portion 402 and the restriction by the restricting portion 402 is released.
  • each of the easily deformable portions 112 can be curved and deformed in a bow shape toward the outside by the pressing force from the operation member 11B.
  • the 2nd plunger part 8B can move toward the front-end
  • each easily deformable portion 112 is curved and deformed in a bow shape in the second state, but is not limited thereto, and may be one that breaks in the second state. .
  • liquid administration device of the present invention has been described above with respect to the illustrated embodiment. However, the present invention is not limited to this, and each component constituting the liquid administration device can have any function that can exhibit the same function. Can be substituted. Moreover, arbitrary components may be added.
  • liquid administration device of the present invention may be a combination of any two or more configurations (features) of the above embodiments.
  • the puncture needle has a needle tube that is a double-ended needle in each of the embodiments described above, but is not limited to this, and may have a needle tube in which the proximal end needle tip is omitted.
  • the needle tube is already in communication with the cylinder in advance, that is, in an unused state.
  • the operating member includes a first spreading portion (bar-shaped body) in which the first plunger portion has a plurality of plate pieces, and the second plunger portion enters between the plate pieces.
  • the present invention is not limited to this, and the second plunger portion has a plurality of plate pieces, and the first plunger portion is inserted between the plate pieces.
  • the restricting means for restricting the movement of the cover member is such that in each of the embodiments, the elastic piece is disposed on the inner peripheral side of the cover member, and the engaging portion with which the elastic piece engages is disposed on the outer peripheral side of the cylindrical body.
  • the elastic piece may be arranged on the outer peripheral side of the cylindrical body, and the engaging portion with which the elastic piece engages may be arranged on the inner peripheral side of the cover member.
  • the liquid administration device of the present invention has a bottomed cylindrical shape having a bottom portion at the distal end portion, and a cylindrical body filled with a liquid inside thereof, and a sharp distal needle tip at least at the distal end and the proximal end.
  • a needle tube that is provided on the distal end side of the cylindrical body and can communicate with the cylindrical body, a gasket that can slide within the cylindrical body, and pressing the gasket toward the distal direction to cause the liquid to flow into the needle tube
  • an operation member having a lock means for maintaining a positional relationship between the first plunger portion and the second plunger portion, and the operation member is maintained in the positional relationship by the lock means,
  • the gas is added to the gas A first state in which the base is pressed to the limit of movement in contact with the bottom portion, and the maintenance of the positional relationship is released from the first state, and the second plunger portion is moved relative to the first plunger portion.
  • the second state of moving toward the distal end direction can be taken. Therefore, operability is excellent and liquid leakage can be prevented.
  • the liquid administration device of the present invention has industrial applicability.
  • Liquid administration device 1 Inner cylinder (tubular body) 12 bottom part 121 mouth part 122 convex part 123 protrusion 13 side wall 132 flange part 133 inner peripheral part 14 inner cylinder main body 141 engaging part 15 sealing member (sealing part) 151 Concave portion 16 Fixing member 2 Double-ended needle 21 Tip side needle tip 22 Flow path 23 Base end side needle tip 3 Gaskets 31 and 32 Projection portion 33 Concavity 6 Cover member 61 Outer cylinder portion 62 Inner cylinder portion 621 Tip wall portion 622 Opening portion 63 Connection portion 64 Elastic piece 7, 7A, 7B First plunger portion 71 Connection portion 72 Plate piece 721 Inclined surface 73 Flange portion 74, 75 Columnar portion 751 Base end surface 8, 8A, 8B Second plunger portion 81 Top plate 82 First 1 spreading portion 821 taper portion 83 second spreading portion 84 first claw portion 85 second claw portion 86 pressing portion 861 tip surface 87 columnar portion 9 support member 91 fixing portion (supporting portion) 92 Wall part

Abstract

L'invention concerne un appareil d'administration de liquide, qui comprend : un corps cylindrique qui a une forme cylindrique inférieure ayant une partie inférieure sur une partie extrémité distale et à l'intérieur duquel est introduit un liquide ; un tube d'aiguille, qui a une pointe d'aiguille pointue côté extrémité distale sur au moins l'extrémité distale parmi l'extrémité distale et une extrémité de base, est disposé sur le côté extrémité distale du corps cylindrique et peut communiquer avec le corps cylindrique ; un joint qui est apte à coulisser à l'intérieur du corps cylindrique ; un élément fonctionnel pour réaliser une opération de pression dans laquelle le joint est pressé vers la direction d'extrémité distale, permettant ainsi de décharger le liquide du tube d'aiguille, et qui a une première partie piston plongeur qui est reliée à un côté extrémité de base du joint et une seconde partie piston plongeur qui est disposée sur le côté extrémité de base du premier piston plongeur ; et un moyen de verrouillage pour maintenir la relation de position entre la première partie piston plongeur et la seconde partie piston plongeur. L'élément fonctionnel est apte à adopter un premier état dans lequel, lorsque la relation de position est maintenue par le moyen de verrouillage, le joint est pressé jusqu'à la limite de mouvement où le joint entre en contact avec la partie inférieure, et un second état dans lequel le maintien de la relation de position à partir du premier état est annulé et la seconde partie piston plongeur est déplacée vers la direction d'extrémité distale par rapport à la première partie piston plongeur.
PCT/JP2012/067371 2012-07-06 2012-07-06 Appareil d'administration de liquide WO2014006754A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/JP2012/067371 WO2014006754A1 (fr) 2012-07-06 2012-07-06 Appareil d'administration de liquide
JP2014523535A JP5897125B2 (ja) 2012-07-06 2012-07-06 液体投与具

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2012/067371 WO2014006754A1 (fr) 2012-07-06 2012-07-06 Appareil d'administration de liquide

Publications (1)

Publication Number Publication Date
WO2014006754A1 true WO2014006754A1 (fr) 2014-01-09

Family

ID=49881541

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2012/067371 WO2014006754A1 (fr) 2012-07-06 2012-07-06 Appareil d'administration de liquide

Country Status (2)

Country Link
JP (1) JP5897125B2 (fr)
WO (1) WO2014006754A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS48106995U (fr) * 1972-03-13 1973-12-11
JPS5113954B1 (fr) * 1969-10-07 1976-05-06

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136714A0 (en) * 1997-12-16 2001-06-14 Meridian Medical Technologies Automatic injector for administrating a medicament
US6139526A (en) * 1998-10-01 2000-10-31 Bedner; Richard J. Single use self disabling safety syringe
JP4413978B2 (ja) * 2002-09-06 2010-02-10 大日本住友製薬株式会社 医療用注射器
JP5372350B2 (ja) * 2006-08-25 2013-12-18 大日本住友製薬株式会社 注射器及びプランジャロッド
CN103118723B (zh) * 2010-08-19 2017-03-22 诺沃—诺迪斯克有限公司 具有针罩、衰减机构和可听和触觉反馈的用于手动针插入的医疗自动注射装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113954B1 (fr) * 1969-10-07 1976-05-06
JPS48106995U (fr) * 1972-03-13 1973-12-11

Also Published As

Publication number Publication date
JPWO2014006754A1 (ja) 2016-06-02
JP5897125B2 (ja) 2016-03-30

Similar Documents

Publication Publication Date Title
JP5865498B2 (ja) 液体投与具
JP6038020B2 (ja) 液体注入具
US9498582B2 (en) Liquid administration device
US9192733B2 (en) Puncture needle assembly and medicinal liquid injection device
JP6068467B2 (ja) 医薬品容器
WO2009096227A1 (fr) Ensemble aiguille de ponction et dispositif d'injection de liquide médicinal
JP6125187B2 (ja) 液体投与具
JP6360470B2 (ja) 液体投与具
JP5897125B2 (ja) 液体投与具
JP2013188431A (ja) シリンジ
JP6178306B2 (ja) 液体投与具
WO2014115241A1 (fr) Instrument d'administration de liquide
JP6215550B2 (ja) 液体投与具
JP6104747B2 (ja) 液体投与具
JPWO2018180567A1 (ja) 薬液投与具およびガスケット付勢部材組立体
WO2013146049A1 (fr) Dispositif d'administration de liquide
JP6165131B2 (ja) 液体投与具
WO2014013547A1 (fr) Instrument pour administration de liquide
WO2013145998A1 (fr) Ensemble d'administration de liquide

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12880308

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2014523535

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12880308

Country of ref document: EP

Kind code of ref document: A1