WO2014005423A1 - 一种生发制剂及其制备方法 - Google Patents
一种生发制剂及其制备方法 Download PDFInfo
- Publication number
- WO2014005423A1 WO2014005423A1 PCT/CN2013/070064 CN2013070064W WO2014005423A1 WO 2014005423 A1 WO2014005423 A1 WO 2014005423A1 CN 2013070064 W CN2013070064 W CN 2013070064W WO 2014005423 A1 WO2014005423 A1 WO 2014005423A1
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- Prior art keywords
- black
- root
- sesame
- preparation
- hair
- Prior art date
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Definitions
- the invention relates to a traditional Chinese medicine preparation for germinating action, in particular to a formula and a preparation method of the traditional Chinese medicine preparation relating to the hair growth effect. Background technique
- the object of the present invention is to provide a formula for preparing a hair growth effect and a preparation method thereof according to the above-mentioned deficiencies, on the basis of the ancestral secret recipe, combined with modern Chinese and Western medicine technology, and in particular to provide a hair growth effect.
- the prepared preparation can be applied to various types of scalp, and there is no allergic reaction after washing the hair, no toxic and side effects, and the medicine is made. It can quickly penetrate into the skin to achieve the purpose of hair growth, and the cost is low, and the preparation process is simple and easy.
- the preparation of the invention is made up of black sesame oil, black glutinous rice, black bean, white peony, raw shouwu, mulberry leaf, vine, taurus, chuanxiong, white pheasant, cnidium, cypress, black glory, scorpion, a paste preparation prepared from sesame flower, medlar, burdock, lotus root, and medlar root,
- the mass ratio of each component is:
- the preferred raw material quality ratio of the present invention is
- the present invention can also be preferably used as raw material quality with black sesame oil 8 liters black glutinous rice 120g black beans 120g
- the preparation method of the above-mentioned raw Chinese medicine preparation comprises the following steps:
- the cnidium, cypress, black glory, medlar, sesame flower, medlar, burdock, lotus must be proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, then at 50-70 ° C Dry at high temperature, then naturally dry to room temperature for use;
- the above paste preparation is added to the remaining cnidium, arborvitae, Black morning glory, medlar, sesame flower, medlar, burdock, lotus seed mixture, stir evenly;
- the above-mentioned paste preparations are stirred once a day, morning and evening, each time for 10 minutes, after three days, slightly fry for half an hour, and then allowed to stand at room temperature, and then placed in a porcelain jar and served.
- the prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.
- the theoretical basis of the present invention is: Black sesame oil, which has been known as a long-lived high-grade food since ancient times, and sesame contains vitamin E, vitamin B1, linoleic acid, protein, sesame, polypentose, calcium, pity, iron, etc. Substance and a variety of nutrients. Vitamin E, which has the highest content and is the main ingredient, is often called a vitamin to prevent aging. It has a good effect on improving blood circulation and promoting metabolism in the head.
- Black glutinous rice is a variety of rice, belonging to glutinous rice. It is cultivated in a small amount in Sichuan, Guizhou and Yunnan.
- White pelt which is the skin of the perennial herb of the genus Rutaceae, has the effect of clearing heat and dampness, detoxifying and relieving itching. It can be hurricane, dampness, heat, detoxification. Treatment of wind and heat sore, phlegm, skin pruritus, rheumatism, jaundice.
- Shouwu can improve people's signs of aging, such as hair loss, tooth loss, age spots, etc., can promote the improvement of human immunity, and inhibit the deposition of "fat brown pigment" which can make people aging.
- Shouwu can also expand the coronary arteries of the heart, lower blood fat, promote the formation of red blood cells, so it has preventive effects on coronary heart disease, hyperlipidemia, senile anemia, brain decline, signs of premature aging.
- Mulberry leaves are the dry leaves of Mulberry mulberry, also known as mulberry, mulberry, mulberry, and yellow mulberry. They are produced in most parts of the country and have the functions of lowering blood pressure, blood fat, anti-inflammatory, etc., which can evacuate wind and heat. Qingfei Runzao, calming liver and yang, clearing liver and eyesight, cooling blood to stop bleeding. It has been recorded in the ancient Chinese medical directory "The Record of Keeping Lives" that the mulberry leaves can be "retained in the face, black hair, filled with marrow, and dysentery". Vine vine, English name FRUCTUS VITITCIS, was born on the beach, on the river and lake beach. Xin, bitter, slightly cold.
- Achyranthes bidentata the ancient Chinese doctor Li Shizhen said: "The power of nourishing, such as the power of cattle.”
- Achyranthes sinensis bitterness attending cold and dampness, limbs, and knee pain can not bend and stretch, bloody, The heat is burning, and the long-wearing is light and durable.
- Chuanxiong often used to promote blood circulation, hurricane and pain
- Chuanxiong Xin Wenxiang dry go without keeping, can not only disperse, up to the dome; and into the blood, down to blood.
- White peony also known as white peony, is a genus of peony. It has a long history of cultivation in China, is well known both at home and abroad, and its roots are incorporated into medicine. Perennial herbs or sub-shrubs can nourish blood and soften the liver, relieve pain, and absorb yin and sweat.
- Cnidium alias wild carrot
- Cnidium monnieri (L.) Cuss is a dry mature fruit of the umbelliferous plant Cnidium monnieri (L.) Cuss.
- L. umbelliferous plant Cnidium monnieri
- Indications warm kidney and impotence, dampness, hurricane, insecticide.
- For impotence palace cold, cold and wet, wet and low back pain; external treatment of vulvar eczema, vaginal itching, trichomonas vaginitis.
- Caobaizhi a perennial herb, can clear away heat and detoxify, nourish the heart and calm the nerves, and relieve pain.
- heart failure heart palpitations, cough, blood in the sputum, sore throat, fractures, etc.
- Black morning glory the root of the female leeks of the carnation plant. It has the effect of removing phlegm and dehumidifying blood and promoting blood circulation. It plays the role of detoxification to avoid the accumulation of toxins in the human body and affects the growth of hair. ⁇ live, return to the bladder; kidney.
- Sexual taste Weixin; bitterness; temperature. Indications exogenous cold; headache without sweat; oily cold dampness; feng shui edema; sore swollen poison.
- Sesame flower scientific name Physostegia virginiana, sesame flower harvested flowers in summer, used for drying. Seeds contain fatty oil, which can lower blood sugar, increase the glycogen content in the liver and muscle, and have a diarrhea effect. Sesame flowers are flat and sweet. It has hair growth and swelling effect. Can be used to treat hair loss, white hair, frostbite, constipation. ⁇ , the shape is like a sinuous and hollow, slightly curved. It is about 4cm long and about 2cm wide. The surface is yellowish brown, translucent and shiny.
- the head has a filamentous antennae of 1 pair, which has been broken, the compound eye is prominent, the apex of the neck is prominent, the muzzle is developed, the upper lip is short, and the lower lip is elongated into a tubular shape.
- the back of the chest is a cross-shaped lob, the slit is curled inward, and there are 2 pairs of small wings on both sides of the back; It is yellowish brown and fine.
- Abdominal obtuse a total of 9 knots. Light, hollow, and fragile. Odorless, mild. Function: Dissemination of wind heat, rash, pharynx, phlegm and phlegm.
- Burdock a dry mature fruit of the two-year-old herb of the Compositae (Arctium lappa L.). It belongs to the dissolving wind-heating medicine in the solution. Can evacuate wind and heat; clearing away heat and detoxifying rash; Xuanfei Liyan swollen and swollen. Wind-heat cold, warm disease at the beginning; wind heat or lung heat cough, sputum sputum; sore throat; spotted rash; early measles, rash out of the rash and itching; sore swollen poison and phlegm.
- Hemolysis Amaranth The saponin contained in the bulb has a strong hemolysis effect, and the affinity between the saponin and the blood cholesterol is particularly strong, and the molecular complex can form a sharp lipid on the surface of the red blood cell to destroy the red blood cell.
- Saponins can stimulate the gastric mucosa, reflexively cause increased secretion of respiratory mucosa and show sputum effect.
- the combination of the above compositions can enhance the conditioning effect, and is rich in minerals such as vitamin E, vitamin B1, linoleic acid, protein, sesame, polypentose, calcium, pity, iron and the like in black sesame oil.
- the combination of nutrients further enhances the elasticity and luster of the hair, making the hair loose and easy to comb.
- the effect criteria are: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, giving birth to small hair more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and reduction.
- the effect criteria are: significant, hair loss is not obvious, giving birth to small hair more than 10%; effective, giving birth to small hair more than 5%, hair loss is controlled; invalid, hair loss is basically no improvement and reduction.
- the preparation prepared by the invention can be applied to hair and scalp of various characteristics, and has no allergic reaction after washing the hair, has no toxic and side effects, and makes the drug It can quickly penetrate into the skin to achieve the purpose of hair growth, and it has quick effect, good hair growth and hair-raising effect, low cost and easy preparation process.
- Example 1 The preferred raw material quality of the invention is (g):
- the preparation method of the above-mentioned raw Chinese medicine preparation comprises the following steps:
- the cnidium, cypress, black glory, medlar, sesame flower, medlar, burdock, lotus must be proportioned, crushed by a pulverizer and passed through a 80 mesh sieve, and then at a high temperature of 50 ° C Dry, then naturally dry to room temperature for use;
- the above paste preparation is added to the remaining cnidium, cypress, black glory, medlar, sesame flower, medlar, burdock, lotus root mixture, and then stirred evenly; 6), the above-mentioned paste preparations are stirred once a day, morning and evening, each time for 10 minutes, after three days, slightly fry for half an hour, and then allowed to stand at room temperature, and then placed in a porcelain jar and served.
- the prepared cream preparation is used to wipe the scalp alone or to clean the hair. If it is mixed into a common shampoo, the effect will be better.
- the preferred raw material quality of the present invention is (g):
- the preparation method is as in Example 1.
- the mass of each component is (g):
- the preparation method is as in Example 1.
- the mass of each component is (g):
- the preparation method is as in Example 1.
- the mass of each component is (g):
- Black sesame oil 6. 5 liters black glutinous rice 100g black beans 100g white peony skin 80g raw shouwu 60g mulberry leaves 100g jingzi 100g haixiu 80g chuanxiong 80g white peony 100g scorpion 40g cypress cypress 70g black glory 80g ⁇ live 30g sesame flower 15g ⁇ 80g burdock 100g lotus root 80g ⁇ root 60g t
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Abstract
一种生发制剂及制备方法。由黑麻油、黑糯米、黑豆、白藓皮、生首乌、桑叶、蔓荆子、怀牛膝、川芎、白芍、蛇床子、草柏枝、黑牵牛、羌活、芝麻花、蝉蜕、牛蒡子、莲须、韭根经过混合、煎制等步骤制备成膏状制剂。单独用其擦拭头皮或清洗头发,或将其混入到普通洗发液中使用,使药物渗入皮肤吸收。
Description
一种生发制剂及其制备方法
技术领域
本发明涉及一种生发作用的中药制剂,具体的说是涉及这种生发 作用的中药制剂的配方及制备方法。 背景技术
在现代都市高效率、快节奏的工作生活中, 人们的脱发现象日渐 增多,也越来越严重,尤其是年轻人经常为很早就脱落的黑发所苦恼, 目前市场上治疗脱发的药物制剂不少, 但是对于西药来说, 一是价格 比较昂贵, 持续几个疗程的治疗, 给患者增加了不小的经济负担, 二 是长时间的用药容易给身体机能带来一定的副作用;对于市场上的纯 中药, 药效慢, 不稳定, 对头部毛囊的刺激作用虽然暂时有一部分毛 发生出, 如果一旦停止用药, 新生的小毛发容易脱落, 这主要和毛囊 的病变和毛发生长环境缺乏营养有关, 患者需要有一种疗效好, 使生 发持久, 并且价格相对比较低廉的药物来解决上述问题。 发明内容
本发明的目的即在于针对上述不足, 在祖传秘方的基础上, 结合 现代中西医技术, 提供一种生发作用的中药制剂, 具体的说提供这种 生发作用的制剂的配方及制备方法, 本发明制成的制剂, 可以适用于 各种特点的头皮, 用其清洗头发后无过敏反应, 无毒副作用, 使药物
能迅速渗入皮肤, 达到生发的目的, 而且成本低廉、 制取工艺简便易 行。
本发明的技术方案如下所述:
本发明制剂是由黑麻油、黑糯米、 黑豆、 白藓皮、生首乌、桑叶、 蔓荆子、 怀牛膝、 川芎、 白芍、 蛇床子、 草柏枝、 黑牵牛、 羌活、 芝 麻花、 蝉蜕、 牛蒡子、 莲须、 韭根制备成的组合物膏状制剂,
其中各组分的质量配比为:
黑麻油 6-8升 黑糯米 100-150g 黑豆 100-150g
白藓皮 60-80g 生首乌 40-60g 桑叶 80-100g
荆子 100-120g 怀牛膝 80-100g 川芎 60-80g
白芍 80-100g 蛇床子 40-60g 草柏枝 60-70g
黑牵牛 80-100g 羌活 20-30g 芝麻花 15-20g
蝉蜕 60-80g 牛蒡子 80-100g 莲须 80-100g
韭根 60-80g。
为了获得更好的效果, 本发明可优选的原料质量配比为
黑麻油 6-8升 黑糯米 100-120g 黑豆 100-120g
白藓皮 60-70g 生首乌 40-50g 桑叶 80-90g
荆子 100-l lOg 怀牛膝 80-90g 川芎 60-70g
白芍 80-90g 蛇床子 40-50g 草柏枝 60-65g
黑牵牛 80-90g 羌活 20-25g 芝麻花 15-18g
蝉蜕 60-70g 牛蒡子 80-90g 莲须 80-90g
韭根 65-70g。
当然, 为了获得进一步好的效果, 本发明还可优选的原料质量配 黑麻油 8升 黑糯米 120g 黑豆 120g
白藓皮 60g 生首乌 45g 桑叶 85g
荆子 108g 怀牛膝 88g 川芎 65g
白芍 88g 蛇床子 45g 草柏枝 65g
黑牵牛 85g 羌活 20g 芝麻花 18g
蝉蜕 60g 牛蒡子 80g 莲须 85g
韭根 68g。
上述生发中药制剂的制备方法, 包括如下步骤:
1 )、将黑糯米、 黑豆、 白藓皮、 生首乌、 桑叶、 蔓荆子、怀牛膝、 川芎、 白芍按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温下烘干, 然后自然晾到室温备用;
2 )、 将黑麻油放到铁锅内熬沸 3-5次, 然后将黑糯米、 黑豆、 白 藓皮、 生首乌、 桑叶、 蔓荆子、 怀牛膝、 川芎、 白芍的粉末, 下入油 锅内与芝麻香油同煎, 半个小时后取出清油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入粉碎并过 80 目 筛的韭根, 一直搅拌十分钟后, 静置经过至少一夜;
4)、将蛇床子、 草柏枝、 黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的 高温下烘干, 然后自然晾到室温备用;
5 )、在室温状态下,将上述膏状制剂加入剩余的蛇床子、草柏枝、
黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须混合物, 再搅拌均匀;
6)、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三 日后微火煎半小时, 并静置到室温, 然后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。 本发明的理论依据在于: 黑麻油, 自古以来就称为长寿不老的高级食品,芝麻含维生素 E、 维生素 Bl、 亚油酸、 蛋白质、 麻糖、 多缩戊糖、 钙、 憐、 铁等矿物 质和各种丰富的营养成分。其中含量最多,成为主要成分的维生素 E, 又常被人们称为防止衰老的维生素。它对改善头部的血液循环、促进 新陈代谢有很好的效果, 还有不饱和脂肪酸的亚油酸, 它有调节胆固 醇的功能, 因而又被称为 "永葆青春的营养源" 。 我国中医学对芝 麻的药用有较高的认识, 称它是一味强壮剂, 有补血、 润肠、 生津、 通乳、 养发等功效, 适用于身体虚弱、 头发早白、 贫血萎黄、 津液不 足、 大便燥结、 头晕耳鸣等症状。 黑糯米, 是水稻的一个品种, 属于糯米类, 仅四川、 贵州、 云南有少量栽培, 是较珍贵的水稻品种, 分紫粳、 紫糯两种。 紫 米颗粒均匀, 颜色紫黑, 食味香甜, 甜而不腻。 紫米煮饭, 味极 香, 而且又糯, 民间作为补品, 有紫糯米或 "药谷" 之称。 紫米 熬制的米粥清香油亮、 软糯适口, 因其含有丰富的营养, 具有很 好的滋补作用, 因此被人们称为 "补血米" 、 "长寿米" 。 黑糯
米被誉为 "黑珍珠" , 富含蛋白质、 碳水化合物、 B族维生素、 钙、 铁、 钾、 镁等营养元素, 其营养丰富, 多食具有开胃益中、 健脾暖肝、 明目活血、 滑涩补精之功, 对于生发、 妇女产后虚弱、 病后体虚以及贫血、 肾虚均有很好的补养作用。 白藓皮, 为芸香科多年生草本植物白藓的皮, 有清热燥湿, 解毒止痒的功效。 可祛风, 燥湿, 清热, 解毒。 治风热疮毒, 疥 癣, 皮肤痒疹, 风湿痹痛, 黄疸。 生首乌, 功能解毒、 消痈、 润肠通便, 常用于治疗瘰疬疮痈、 风疹瘙痒、 肠燥便秘; 首乌补益肝肾、 益精血、 壮筋骨。 首乌可 改善人的衰老征象, 如脱发、 齿落、 老年斑等, 能促进人体免疫 力的提高, 抑制能让人衰老的 "脂褐素"在身体器官内的沉积。 首乌还能扩张心脏的冠状动脉血管, 降血脂, 促进红细胞的生成, 所以对冠心病、 高血脂症、 老年贫血、 大脑衰退、 早老征象等, 都有预防效果。 桑叶, 是桑科植物桑的干燥叶, 又名家桑、 荆桑、 桑椹树、 黄桑等, 全国大部分地区多有生产, 具有降血压、 血脂、 抗炎等 作用, 可以疏散风热, 清肺润燥, 平抑肝阳, 清肝明目, 凉血止 血。 我国古代医学名录 《保生要录》 中曾有记载, 桑叶可以 "驻 容颜, 乌须发, 补髓填精, 祛疾延年" 。
蔓荆子, 英文名 FRUCTUS VITITCIS, 生于海边、 河湖沙滩上。 辛、 苦, 微寒。 归膀胱、 肝、 胃经。 可以疏散风热, 清利头目。 用于 风热感冒头痛, 齿龈肿痛, 目赤多泪, 目暗不明, 头晕目眩。 我国中 医药典 《药性论》 : "治贼风, 能长髭发。 " 《开宝本草》记载, 蔓 荆子 "味苦、 辛、 平、 温, 无毒。 主风头痛, 脑鸣, 目泪出。 令人光 泽, 脂致, 长须发。 " 怀牛膝(亦称牛膝), 苋科, 系多年生草本植物。怀牛膝药效高, 我国古代名医李时珍说它: "滋补之功, 如牛之力。 ", 牛膝气味苦 酸平, 主治寒湿痿痹、 四肢拘挛, 膝痛不可屈伸, 逐血气, 伤热火烂, 久服轻身耐老。 有补肝肾; 强筋骨; 活血通经; 引火(血)下行; 利 尿通淋等功效, 以达到养发需补肾的功效。 川芎, 常用于活血行气, 祛风止痛, 川芎辛温香燥, 走而不守, 既能行散, 上行可达巅顶; 又入血分, 下行可达血海。 活血祛瘀作用 广泛,适宜瘀血阻滞各种病症; 祛风止痛,效用甚佳,可治头风头痛、 风湿痹痛等症。用于本发明中, 可以充分的对头部进行活血, 增强血 液循环。 白芍, 也称白花芍药, 是毛茛科芍药属植物。在中国已有悠久的 栽培历史, 驰名中外, 其根并入药。 多年生草本或亚灌木, 可以养血 柔肝, 缓中止痛, 敛阴收汗。治胸腹胁肋疼痛, 泻痢腹痛, 自汗盗汗, 阴虚发热, 月经不调, 崩漏。
蛇床子, 别名野胡萝卜子, 为伞形科植物蛇床 Cnidium monnieri (L. ) Cuss.的干燥成熟果实。 夏、 秋二季果实成熟时采收, 除去杂 质, 晒干。 性味: 性温, 味辛、 苦。 功能主治: 温肾壮阳, 燥湿, 祛风, 杀虫。用于阳痿、 宫冷、寒湿带下、湿痹腰痛; 外治外阴湿疹、 妇人阴痒、 滴虫性阴道炎。 草柏枝, 为多年生草本, 可以清热解毒, 养心安神, 止痛。 用于 心脏衰弱, 心悸, 咳嗽, 痰中带血, 咽喉肿痛, 骨折等。 黑牵牛, 为石竹科植物腺花女娄菜的根。 有祛风除湿、 活血通经 的功效, 起到通便排毒的功效, 以避免人体毒素累计, 而影响到头发 的生长。 羌活, 归膀胱; 肾经。 性味: 味辛; 苦; 性温。 主治外感风寒; 头痛无汗; 油印寒湿痹; 风水浮肿; 疮疡肿毒。 芝麻花, 学名 Physostegiavirginiana, 芝麻花夏季采收花朵, 晒干用。种子含脂肪油, 可以降低血糖, 增加肝脏及肌肉中的糖元含 量, 有致泻作用。 芝麻花性平味甘, 平。 有生发, 消肿作用。 可以用 于治疗脱发白发、 冻疮、 便秘。 蝉蜕, 全形似蝉而中空, 稍弯曲。 长约 4cm, 宽约 2cm。 表面黄 棕色, 半透明, 有光泽。头部有丝状触角 1对, 多已断落, 复眼突出, 颈部先端突出, 口吻发达, 上唇宽短, 下唇伸长成管状。 胸部背面呈 十字形裂片,裂口向内卷曲,脊背两旁具有小翅 2对;腹面有足 3对,
被黄棕色细毛。腹部钝圆, 共 9节。体轻, 中空, 易碎。无臭, 味淡。 功能: 宣散风热、 透疹利咽、 祛风止痉。 用于外感风热、 发热恶寒、 咳嗽, 以及风疹、 皮肤瘙痒、 脱发等症。 牛蒡子, 为菊科二年生草本植物牛蒡(学名: Arctium lappa L. ) 的干燥成熟果实。属于解表药中发散风热药。 可以疏散风热; 清热解 毒透疹; 宣肺利咽散肿。 风热感冒、 温病初起; 风热或肺热咳嗽、 咯 痰不畅; 咽喉肿痛; 斑疹不透; 麻疹初期, 疹出不畅及风疹瘙痒; 疮 疡肿毒及痄腮等。 莲须, 睡莲科植物莲的干燥雄蕊。夏季花开时选晴天采收, 盖纸 晒干或阴干。含碳水化合物, 蛋白质, 脂肪, 钙, 憐, 铁等营养物质, 能清心通肾, 固精气, 促进毛发生长, 达到养肾生发效果。 韭, 多年生草本, 具特殊强烈气味。 韭菜的根含硫化物、 甙类和 苦味质。我国典籍《别录》记载, 韭根 "主养发", 它具有抗菌作用: 韭菜鳞茎中中主要含有蒜氨酸(all i in) , 蒜氨本身无抗菌作用, 但 在大蒜酶作用下可转变成大蒜辣素而显示强大的抗菌作用,抗菌范围 广, 对多种革兰阳性、 阴性菌均有抑制作用, 且对真菌, 立克次体及 阿米巴原虫也有效; 溶血作用: 韭菜鳞茎中所含的皂甙有很强的溶血 作用, 因皂甙与血中胆固醇的亲和力特别强, 可形成分子络合物作用 于红细胞表面尖脂质而破坏红细胞之故。祛痰作用: 皂甙能刺激胃粘 膜, 反射性地引起呼吸道粘膜分泌增加而显示祛痰作用。
上述组合物的配伍组合, 可以增强调理作用, 并与黑麻油中的维 生素 E、 维生素 Bl、 亚油酸、 蛋白质、 麻糖、 多缩戊糖、 钙、 憐、 铁 等矿物质和各种丰富的营养成分相结合进一步增进头发的弹性和光 泽, 使头发疏松易梳。 临床实验 1:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2011 年 2月到 2011年 7月的 6个月时间。
2 )、 观察对象: 选择 40例病例: 男 20例, 女 20例; 年龄: 16 一 25岁 18例, 25— 35岁 22例; 职业: 学生 10例, 工人 10例, 农 民 5例, 教师 10例, 其他 5例。 病程: 从发病到就诊时间, 2年内 20例, 2— 4年 10例, 4年以上 10例。
3 )、 使用方法: 将本发明制剂洗发液清洗头发, 每日 3次, 每次 饭后 1小时清洗, 1个月为 1疗程, 6个疗程作为疗效观察。
4)、 观察效果:
效果标准分为: 显著, 脱发不明显, 生出小毛发 10%以上; 有效, 生出小毛发 5%以上, 脱发得到控制; 无效, 脱发基本没有改善和减 轻。
结果 40例中, 显著 20例, 有效 13例, 无效 7例, 总有效率为 82. 5%。
临床实验 2:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2012
年 1月到 2012年 6月的 6个月时间。
2 )、 观察对象: 选择 20例病例: 男 10例, 女 10例; 年龄: 16 一 25岁 8例, 25— 35岁 12例; 职业: 学生 10例, 工人 2例, 农民 2例, 教师 2例, 其他 4例。病程: 从发病到就诊时间, 2年内 10例, 2— 4年 5例, 4年以上 5例。
3 )、 使用方法: 将本发明制剂清洗头发, 每日 3次, 每次饭前 1 小时清洗, 1个月为 1疗程, 6个疗程作为疗效观察。
4)、 观察效果:
效果标准分为: 显著, 脱发不明显, 生出小毛发 10%以上; 有效, 生出小毛发 5%以上, 脱发得到控制; 无效, 脱发基本没有改善和减 轻。
结果 20例中, 显著 14例, 有效 2例, 无效 4例, 总有效率为
80%。
结合以上临床数据及本发明的理论依据, 可见其有益效果在于, 本发明制成的制剂, 可以适用于各种特点的毛发和头皮, 用其清洗头 发后无过敏反应, 无毒副作用, 使药物能迅速渗入使皮肤吸收, 达到 生发的目的, 而且见效快, 生发养发效果好, 成本低廉、 制取工艺简 便易行。 具体实舫式
下面结合实施例对本发明详细加以说明:
实施例 1:
本发明优选的原料质量为 (克):
黑麻油 8升 黑糯米 100g 黑豆 100g
白藓皮 60g 生首乌 40g 桑叶 80g
荆子 100g 怀牛膝 80g 川芎 60g
白芍 80g 蛇床子 40g 草柏枝 60g
黑牵牛 80g 羌活 20g 芝麻花 15g
蝉蜕 60g 牛蒡子 80g 莲须 80g
韭根 60g。
上述生发中药制剂的制备方法, 包括如下步骤:
1 )、将黑糯米、 黑豆、 白藓皮、 生首乌、 桑叶、 蔓荆子、怀牛膝、 川芎、 白芍按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50°C 的高温下烘干, 然后自然晾到室温备用;
2 )、 将黑麻油放到铁锅内熬沸 3次, 然后将黑糯米、 黑豆、 白藓 皮、 生首乌、 桑叶、 蔓荆子、 怀牛膝、 川芎、 白芍的粉末, 下入油锅 内与芝麻香油同煎, 半个小时后取出清油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入粉碎并过 80 目 筛的韭根, 一直搅拌十分钟后, 静置经过至少一夜;
4)、将蛇床子、 草柏枝、 黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50°C的高温 下烘干, 然后自然晾到室温备用;
5 )、在室温状态下,将上述膏状制剂加入剩余的蛇床子、草柏枝、 黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须混合物, 再搅拌均匀;
6)、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三 日后微火煎半小时, 并静置到室温, 然后装于瓷罐后即成。
制取的膏状制剂单独使用擦拭头皮或清洗头发,如果将其混入到 普通的洗发液中使用, 效果会更好。
实施例 2:
本发明还可优选的原料质量为 (克):
黑糯米 150g 黑豆 150g
生首乌 60g 桑叶 lOOg
怀牛膝 lOOg 川芎 80g
白芍 lOOg 蛇床子 60g 草柏枝 70g
黑牵牛 lOOg 羌活 30g 芝麻花 20g
蝉蜕 80g 牛蒡子 lOOg 莲须 lOOg
韭根 80g。
制备方法如实施例 1。
实施例 3:
其中各组分的质量为 (克):
黑麻油 8升 黑糯米 120g 黑豆 120g
白藓皮 65g 生首乌 45g 桑叶 85g
蔓荆子 105g 怀牛膝 85g 川芎 65g
白芍 85g 蛇床子 45g 草柏枝 65g
黑牵牛 85g 羌活 25g 芝麻花 20g
蝉蜕 65g 牛蒡子 85g 莲须 85g
韭根 65g。
制备方法如实施例 1。
实施例 4:
其中各组分的质量为 (克):
黑麻油 6升 黑糯米 110g 黑豆 110g 白藓皮 68g 生首乌 48g 桑叶 88g 荆子 90g 怀牛膝 90g 川芎 68g 白芍 88g 蛇床子 48g 草柏枝 68g 黑牵牛 88g 羌活 28g 芝麻花 18g 蝉蜕 68g 牛蒡子 880g 莲须 88g 韭根 68g。
制备方法如实施例 1。
实施例 5:
其中各组分的质量为 (克):
黑麻油 6. 5升 黑糯米 100g 黑豆 100g 白藓皮 80g 生首乌 60g 桑叶 100g 荆子 100g 怀牛膝 80g 川芎 80g 白芍 100g 蛇床子 40g 草柏枝 70g 黑牵牛 80g 羌活 30g 芝麻花 15g 蝉蜕 80g 牛蒡子 100g 莲须 80g 韭根 60gt
制备方法如实施例 1
上述实施例仅是本发明众多实施方式的几种,如将各配方按技术 方案中的比例加大或减小药量, 制得的这种生发制剂疗效并不受影 响, 也将落在本发明的权利保护范围之内。
Claims
1、 一种生发中药制剂的配方, 其特征在于, 本发明制剂是由黑 麻油、 黑糯米、 黑豆、 白藓皮、 生首乌、 桑叶、 蔓荆子、 怀牛膝、 川 芎、 白芍、 蛇床子、 草柏枝、 黑牵牛、 宪活、 芝麻花、 蝉蜕、 牛蒡子、 莲须、 韭根制备成的组合物膏状制剂,
其中各组分的质量配比为:
黑麻油 6-8升 黑糯米 100-150g 黑豆 100-150g
白藓皮 60-80g 生首乌 40-60g 桑叶 80-100g
荆子 100-120g 怀牛膝 80-100g 川芎 60-80g
白芍 80-100g 蛇床子 40-60g 草柏枝 60-70g
黑牵牛 80-100g 羌活 20-30g 芝麻花 15-20g
蝉蜕 60-80g 牛蒡子 80-100g 莲须 80-100g
韭根 60-80g。
2、 根据权利要求 1所述的一种生发中药制剂的配方, 其特征还 在于, 各组分的质量配比为:
黑麻油 6-8升 黑糯米 100-120g 黑豆 100-120g
白藓皮 60-70g 生首乌 40-50g 桑叶 80-90g
荆子 100-l lOg 怀牛膝 80-90g 川芎 60-70g
白芍 80-90g 蛇床子 40-50g 草柏枝 60-65g
黑牵牛 80-90g 羌活 20-25g 芝麻花 15-18g
蝉蜕 60-70g 牛蒡子 80-90g 莲须 80-90g
韭根 65-70g。
3、 根据权利要求 1或 2所述的一种生发中药制剂的配方, 其特 征还在于: 各组分的质量配比为:
黑麻油 8升 黑糯米 120g 黑豆 120g
白藓皮 60g 生首乌 45g 桑叶 85g
荆子 108g 怀牛膝 88g 川芎 65g
白芍 88g 蛇床子 45g 草柏枝 65g
黑牵牛 85g 羌活 20g 芝麻花 18g
蝉蜕 60g 牛蒡子 80g 莲须 85g
韭根 68g。
4、 一种生发中药制剂的制备方法, 其特征在于, 其包括如下;
1 )、将黑糯米、 黑豆、 白藓皮、 生首乌、 桑叶、 蔓荆子、怀牛膝、 川芎、 白芍按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的高温下烘干, 然后自然晾到室温备用;
2 )、 将黑麻油放到铁锅内熬沸 3-5次, 然后将黑糯米、 黑豆、 白 藓皮、 生首乌、 桑叶、 蔓荆子、 怀牛膝、 川芎、 白芍的粉末, 下入油 锅内与芝麻香油同煎, 半个小时后取出清油油备用;
3 )、 将上述清油放入陶瓷罐子内盛放, 然后加入粉碎并过 80 目 筛的韭根, 一直搅拌十分钟后, 静置经过至少一夜;
4)、将蛇床子、 草柏枝、 黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须按比例配好, 经过粉碎机粉碎并过 80目筛, 然后在 50— 70°C的 高温下烘干, 然后自然晾到室温备用;
5)、在室温状态下,将上述膏状制剂加入剩余的蛇床子、草柏枝、 黑牵牛、 羌活、 芝麻花、 蝉蜕、 牛蒡子、 莲须混合物, 再搅拌均匀; 6 )、 将上述膏状制剂每日早、 晚各搅拌一次, 每次 10分钟, 三日后 微火煎半小时, 并静置到室温, 然后装于瓷罐后即成。
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CN104398663A (zh) * | 2014-11-11 | 2015-03-11 | 覃永红 | 一种乌发胶囊 |
CN111773167A (zh) * | 2020-08-18 | 2020-10-16 | 黄雯琦 | 一种产后月子期女性专用洗发水及其制备方法 |
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CN102698117B (zh) * | 2012-07-05 | 2013-07-03 | 袁志贤 | 一种生发中药制剂及其制备方法 |
CN102698118B (zh) * | 2012-07-05 | 2013-10-09 | 田志远 | 一种乌发中药制剂及制备方法 |
CN102961317B (zh) * | 2012-12-14 | 2014-05-28 | 柳州两面针股份有限公司 | 中药洗发护发剂 |
CN103301342A (zh) * | 2013-07-08 | 2013-09-18 | 袁志贤 | 一种促进生发中药制剂的配方及制备方法 |
WO2015006895A1 (zh) * | 2013-07-15 | 2015-01-22 | Tian Yi Er | 一种生发中药制剂的配方及制备方法 |
CN103316322A (zh) * | 2013-07-15 | 2013-09-25 | 田艺儿 | 一种生发中药制剂的配方及制备方法 |
DE102014015221A1 (de) | 2013-10-16 | 2015-04-16 | S & V Technologies Gmbh | Zusammensetzung zur Stimulierung des Haarwachstums |
CN108607049A (zh) * | 2018-06-08 | 2018-10-02 | 欧晋 | 一种生发组合物及其制备方法 |
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CN111773167A (zh) * | 2020-08-18 | 2020-10-16 | 黄雯琦 | 一种产后月子期女性专用洗发水及其制备方法 |
CN111773167B (zh) * | 2020-08-18 | 2023-09-12 | 黄雯琦 | 一种产后月子期女性专用洗发水及其制备方法 |
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