WO2013190455A3 - Procédé pour la préparation de chlorhydrate de lurasidone - Google Patents

Procédé pour la préparation de chlorhydrate de lurasidone Download PDF

Info

Publication number
WO2013190455A3
WO2013190455A3 PCT/IB2013/054975 IB2013054975W WO2013190455A3 WO 2013190455 A3 WO2013190455 A3 WO 2013190455A3 IB 2013054975 W IB2013054975 W IB 2013054975W WO 2013190455 A3 WO2013190455 A3 WO 2013190455A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
lurasidone
lurasidone hydrochloride
hydrochloride
base
Prior art date
Application number
PCT/IB2013/054975
Other languages
English (en)
Other versions
WO2013190455A2 (fr
Inventor
V. Vijayabaskar
S. Srimurugan
R.V. Sathish KUMAR
Munusamy Jayamani
Original Assignee
Shasun Pharmaceuticals Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shasun Pharmaceuticals Limited filed Critical Shasun Pharmaceuticals Limited
Publication of WO2013190455A2 publication Critical patent/WO2013190455A2/fr
Publication of WO2013190455A3 publication Critical patent/WO2013190455A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention porte sur un procédé pour la préparation de chlorhydrate de lurasidone présentant un profil d'impuretés moindre, consistant à isoler de la lurasidone sous forme de base sous forme d'un solide et soumettre la base à un mélange alcool isopropylique-acide chlorhydrique.
PCT/IB2013/054975 2012-06-18 2013-06-18 Procédé pour la préparation de chlorhydrate de lurasidone WO2013190455A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2411/CHE/2012 2012-06-18
IN2411CH2012 2012-06-18

Publications (2)

Publication Number Publication Date
WO2013190455A2 WO2013190455A2 (fr) 2013-12-27
WO2013190455A3 true WO2013190455A3 (fr) 2014-03-20

Family

ID=49769624

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/054975 WO2013190455A2 (fr) 2012-06-18 2013-06-18 Procédé pour la préparation de chlorhydrate de lurasidone

Country Status (1)

Country Link
WO (1) WO2013190455A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ306203B6 (cs) * 2013-12-06 2016-09-29 Zentiva, K. S Způsob syntézy lurasidonu
WO2017154021A1 (fr) * 2016-03-09 2017-09-14 Zcl Chemicals Ltd. Procédé amélioré de préparation de base de lurasidone et de ses intermédiaires
CN105891392A (zh) * 2016-03-29 2016-08-24 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定盐酸鲁拉西酮中间体有关物质的方法
CN106397424A (zh) * 2016-03-30 2017-02-15 北京万全德众医药生物技术有限公司 盐酸鲁拉西酮氧化杂质的一种制备方法
CN110734434B (zh) * 2019-11-19 2022-11-11 湖南洞庭药业股份有限公司 制备鲁拉西酮及其盐的方法
CN115073444A (zh) * 2022-08-05 2022-09-20 山东科源制药股份有限公司 一种盐酸鲁拉西酮环氧杂质的精制去除方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532372A (en) * 1990-07-06 1996-07-02 Sumitomo Pharmaceuticals Company, Ltd. Imide derivatives, and their production and use
US7605260B2 (en) * 2003-07-29 2009-10-20 Dainippon Sumitomo Pharma Co., Ltd. Process for producing imide compound
WO2013030722A1 (fr) * 2011-08-26 2013-03-07 Ranbaxy Laboratories Limited Chlorhydrate de lurasidone cristallin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532372A (en) * 1990-07-06 1996-07-02 Sumitomo Pharmaceuticals Company, Ltd. Imide derivatives, and their production and use
US7605260B2 (en) * 2003-07-29 2009-10-20 Dainippon Sumitomo Pharma Co., Ltd. Process for producing imide compound
WO2013030722A1 (fr) * 2011-08-26 2013-03-07 Ranbaxy Laboratories Limited Chlorhydrate de lurasidone cristallin

Also Published As

Publication number Publication date
WO2013190455A2 (fr) 2013-12-27

Similar Documents

Publication Publication Date Title
JOP20210065A1 (ar) عملية لتحضير 5- فلورو-1h- بيرازولوبيريدينات مستبدلة
WO2011138281A3 (fr) Procédé de production de dithiine-tétracarboxy-diimides
WO2013190455A3 (fr) Procédé pour la préparation de chlorhydrate de lurasidone
WO2014014835A8 (fr) Formes cristallines d'un inhibiteur de la prolyl hydroxylase
WO2012068234A3 (fr) Composés antiviraux
WO2010139981A3 (fr) Procédés d'élaboration de formes cristallines
WO2012015999A3 (fr) Procédé de préparation de mésylate d'imatinib
WO2014041559A3 (fr) Procédé de préparation d'étéxilate de dabigatran et ses intermédiaires
NZ602578A (en) Polymorphic forms st-246 and methods of preparation
WO2016092561A3 (fr) Nouveaux polymorphes d'ivacaftor, procédé de préparation de cette molécule et composition pharmaceutique la contenant
WO2017134684A3 (fr) Procédé amélioré de préparation d'ibrutinib
WO2015044853A3 (fr) Procédé de préparation de fumarate de diméthyle
WO2016142819A3 (fr) Nouveau procédé de préparation de ranolazine
MX339361B (es) Derivados de alternano.
WO2014125270A8 (fr) Procédé de production de sulfate d'atazanavir
MY164880A (en) Process for the preparation of isoxazolyl-methoxy-nicotinic acids
WO2016088081A8 (fr) Procédés de préparation d'ertugliflozine
SG10201901578UA (en) Processes for the preparation of pyrimidinylcyclopentane compounds
WO2017093866A3 (fr) Procédé de préparation amélioré de carmin d'indigo
WO2011095985A3 (fr) Sels de rasagiline et procédés de preparation de ces derniers
WO2014178064A3 (fr) Procédé amélioré de préparation de maléate de fluvoxamine
WO2010122575A3 (fr) Procédé de préparation de palipéridone pure
WO2009098082A3 (fr) Composés anti-infectieux et anti-tumoraux isolés à partir de lianes tropicales
WO2014195977A3 (fr) Nouveaux polymorphes de vismodegib
WO2014102759A3 (fr) Procédé de préparation de dasatinib et de ses intermédiaires

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13806775

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 13806775

Country of ref document: EP

Kind code of ref document: A2