WO2014195977A3 - Nouveaux polymorphes de vismodegib - Google Patents

Nouveaux polymorphes de vismodegib Download PDF

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Publication number
WO2014195977A3
WO2014195977A3 PCT/IN2014/000381 IN2014000381W WO2014195977A3 WO 2014195977 A3 WO2014195977 A3 WO 2014195977A3 IN 2014000381 W IN2014000381 W IN 2014000381W WO 2014195977 A3 WO2014195977 A3 WO 2014195977A3
Authority
WO
WIPO (PCT)
Prior art keywords
vismodegib
novel polymorphs
novel
preparation
provides
Prior art date
Application number
PCT/IN2014/000381
Other languages
English (en)
Other versions
WO2014195977A2 (fr
Inventor
Bandi Parthasaradhi Reddy
Kura Rathnakar Reddy
Dasari Muralidhara Reddy
Itiyala Srinivas Reddy
Bandi Vamsi Krishna
Original Assignee
Hetero Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Research Foundation filed Critical Hetero Research Foundation
Publication of WO2014195977A2 publication Critical patent/WO2014195977A2/fr
Publication of WO2014195977A3 publication Critical patent/WO2014195977A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une nouvelle forme cristalline de vismodegib, un procédé de préparation correspondant et des compositions pharmaceutiques contenant du vismodegib. La présente invention concerne une nouvelle forme amorphe de vismodegib, son procédé de préparation et des compositions pharmaceutiques contenant du vismodegib.
PCT/IN2014/000381 2013-06-05 2014-06-04 Nouveaux polymorphes de vismodegib WO2014195977A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2449/CHE/2013 2013-06-05
IN2449CH2013 2013-06-05

Publications (2)

Publication Number Publication Date
WO2014195977A2 WO2014195977A2 (fr) 2014-12-11
WO2014195977A3 true WO2014195977A3 (fr) 2015-11-12

Family

ID=52008674

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2014/000381 WO2014195977A2 (fr) 2013-06-05 2014-06-04 Nouveaux polymorphes de vismodegib

Country Status (1)

Country Link
WO (1) WO2014195977A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022271109A1 (fr) * 2021-06-23 2022-12-29 Deva Holding Nouveau polymorphe de vismodégib et son procédé de préparation
WO2023140809A1 (fr) * 2022-01-20 2023-07-27 Deva Holding Nouveau polymorphe de vismodégib et procédé de préparation
WO2023194300A1 (fr) 2022-04-05 2023-10-12 Synthon B.V. Formes solides de vismodégib

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888364B2 (en) * 2004-09-02 2011-02-15 Curis, Inc. Pyridyl inhibitors of hedgehog signalling
US20120184529A1 (en) * 2011-01-14 2012-07-19 Demario Mark D Combination therapy
US20120196865A1 (en) * 2009-07-24 2012-08-02 Universite De Strasbourg Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888364B2 (en) * 2004-09-02 2011-02-15 Curis, Inc. Pyridyl inhibitors of hedgehog signalling
US20120196865A1 (en) * 2009-07-24 2012-08-02 Universite De Strasbourg Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway
US20120184529A1 (en) * 2011-01-14 2012-07-19 Demario Mark D Combination therapy

Also Published As

Publication number Publication date
WO2014195977A2 (fr) 2014-12-11

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