WO2013110840A1 - Composition cosmétique pour traiter les cheveux et le cuir chevelu - Google Patents

Composition cosmétique pour traiter les cheveux et le cuir chevelu Download PDF

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Publication number
WO2013110840A1
WO2013110840A1 PCT/ES2013/070025 ES2013070025W WO2013110840A1 WO 2013110840 A1 WO2013110840 A1 WO 2013110840A1 ES 2013070025 W ES2013070025 W ES 2013070025W WO 2013110840 A1 WO2013110840 A1 WO 2013110840A1
Authority
WO
WIPO (PCT)
Prior art keywords
cosmetic composition
hair
composition according
scalp
agent
Prior art date
Application number
PCT/ES2013/070025
Other languages
English (en)
Spanish (es)
Inventor
Manuela Bermudez Vico
Lorenzo Delpani
Maria Luisa HARO TOBALINA
Laura TOBELLA LLERENA
Original Assignee
The Colomer Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Colomer Group filed Critical The Colomer Group
Publication of WO2013110840A1 publication Critical patent/WO2013110840A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Definitions

  • the present invention relates to a cosmetic composition for the hair and scalp to delay its aging by increasing the cellular longevity of the scalp and strengthening the hair.
  • the scalp also suffers aggressions due to menopause, tobacco, diets, medications and external agents such as chemical treatments (for example color and permanent treatments), sunrays, pollution and washing processes. These factors also accelerate the aging of the scalp cells and weaken the hair, losing vitality, elasticity and firmness. Hair becomes porous, dry, matte, with less volume, finer, fragile and weaker.
  • the aging of the skin and scalp is determined by two factors:
  • ROS free radicals
  • REPLACEMENT SHEET (Rule 26) Biological clock regulation: cells can divide a limited number of times. This possibility of replication is foreseen in the genetic pattern. The cells stop dividing because the telomeres, ends of the chromosomes, become shorter and shorter in each cell division and cannot protect the chromosomes as such.
  • the holders of the present invention have designed a product for the scalp to delay their aging, and provide shine and volume to the hair.
  • This product has a strengthening and revitalizing effect on the hair, so that it rejuvenates its appearance, giving it a healthier appearance.
  • the object of the present invention is to develop a product to increase the longevity of the hair leather cell, based on a combination of
  • REPLACEMENT SHEET (Rule 26) active ingredients that act on the scalp to combat the visible and invisible signs of hair aging derived from genetic inheritance and the environment.
  • a cosmetic composition suitable for increasing firmness, elasticity and restructuring of the skin and / or for delaying cellular senescence comprising at least one antioxidant agent, an ingredient that delays aging of scalp cells, a soothing and / or anti-irritant agent in a cosmetically acceptable vehicle for topical application on the scalp.
  • the oxidizing agent is selected from tocopherol derivatives, preferably tocopherol acetate (vitamin E derivative); vitamin C derivatives; flavonoids, preferably aspalatine, orientine and quercitin (contained in Rooibos tea extract), beta-carotenes, glutathione, selenium, zinc or mixtures thereof.
  • tocopherol derivatives preferably tocopherol acetate (vitamin E derivative); vitamin C derivatives; flavonoids, preferably aspalatine, orientine and quercitin (contained in Rooibos tea extract), beta-carotenes, glutathione, selenium, zinc or mixtures thereof.
  • the ingredient that slows the aging of the scalp cells is selected from retinol derivatives, preferably retinol palmitate (vitamin A derivative), baicalin, tiliroside and aloe.
  • the soothing and / or anti-irritant agent is selected from bisabolol, acetyl dipeptide-l-cetyl ester, allantoin or mixtures thereof.
  • the cosmetic composition additionally contains a hair conditioning agent.
  • the hair conditioning agent is selected from glycerin, pantothenic acid (vitamin B5) and its derivatives, maltodextrin, actin
  • REPLACEMENT SHEET (Rule 26) hydrolyzed, meadowfoamate of dimethicone PEG-8 or mixture thereof.
  • the cosmetic composition also contains at least one extract of seaweed and / or seawater.
  • the seaweed is selected from brown algae ⁇ Pheophyceas), preferably Fucus vesiclesus, red algae ⁇ Rhodophyceas), green algae ⁇ Chlorophyceas), preferably Cod ⁇ um tomentosum, Sp ⁇ rul ⁇ na, Chlorella, Dunal ⁇ ella or mixtures thereof.
  • kits comprising a) a cosmetic composition suitable for increasing firmness, elasticity and restructuring of the skin and / or for delaying cellular senescence comprising at least one antioxidant agent, an ingredient that delays the aging of the scalp cells, a soothing and / or anti-irritant agent in a cosmetically acceptable vehicle for topical application on the scalp, b) a device to facilitate the application of the cosmetic composition on the scalp.
  • the device for applying the cosmetic composition on the scalp is selected from an applicator, an eyedropper, a spray pump or single dose ampoules.
  • the kit comprising said cosmetic composition allows a treatment for hair and scalp care as described above specially designed for hair that is weakened, fragile, less dense, dry, rough, brittle, malnourished, stiff and dull, and / or has been mistreated by external conditions, either environmental or physicochemical, that have been deteriorating the hair until it lost its balance and natural beauty.
  • Vitamin E has a great capacity to prevent the formation of free radicals, and is used in cosmetics to help fight "oxidative stress”.
  • Vitamin C is present in organisms mainly in the liver, pituitary, crystalline, leukocytes, suprarenal glands, while it is found in lower amounts in the complexion. Many exogenous agents, to which we are exposed every day, can cause an increased consumption of this vitamin and, consequently, produce the corresponding deficiency. It is an antioxidant nutrient that contributes to the defense of some degenerative pathologies, neoplasms, cardiovascular diseases, cataracts and skin aging. It exerts a very beneficial action both with mitigation and prevention of the signs of aging and with the reduction of cellular damage caused by exposure to ultraviolet rays.
  • the cosmetic preparation must guarantee the presence of an active vitamin C so that it can fully carry out its action, since this is usually unstable. Vitamin C helps iron absorption.
  • Rooibos tea extract or red tea does not contain caffeine and the level of polyphenols is low. It contains flavonoids, such as orientin, quercitin and aspalatine (unique in Rooibos tea extract) that provide proven hair color protection characteristics. It is a powerful antioxidant and also has anti-irritant activity. It is considered a very valuable asset for formulations designed for the protection of skin and hair.
  • Beta-carotenes are precursors of vitamin A. They help prevent cell aging, since they reduce free radicals on the body. Stimulate the immune system by strengthening the body's natural defenses and favoring the production of white blood cells
  • Glutathione is a non-protein tripeptide that is derived from amino acids. It is an antioxidant that helps protect cells from reactive oxygen species such as free radicals and peroxides. It exists in the reduced (GSH) and oxidized (GSSG) states. It is the largest endogenous antioxidant produced by cells, directly participating in the neutralization of free radicals and reactive oxygen compounds, as well as the maintenance of exogenous antioxidants, such as vitamins C and E in their reduced (active) forms.
  • Zinc helps prevent hair loss. It maintains the immune system, helping cell division that is really important for healthy hair.
  • Retinol palmitate or vitamin A derivative belongs to the retinoid group. In cosmetics it is considered as the normalizing vitamin. His activity in the epidermis is of particular interest in the field of cosmetics. It is a good regulator of epithelial tissue growth. Together with copper, it is involved in keratinization reactions, and also has a certain synergism with vitamin E. It acts as a regulator in the processes of proliferation and keratinization of skin keratinocytes. It is essential for cell renewal in dry and dehydrated skin, as it slows the thinning of the epidermis and helps maintain elastic skin.
  • Baicalin is a flavonoid contained in the root of the Scutellar ⁇ a Baicalensis Georgi plant. It induces the telomerase expression of fibroblasts (major cells in the dermis) thus maintaining their integrity and inhibiting the process of cellular senescence.
  • Tiliroside is a natural bioflavonoid found in several ethnomedicinal plants. It has antioxidant and anti-inflammatory effect. Protects cells against UV radiation and short waves of visible light.
  • Aloe destroys dead cells, allowing their elimination, and regulates the pH in the three layers of the skin (epidermis, dermis and hypodermis). Protects and regenerates the dermis, exerting a deep bactericidal, moisturizing and cleansing action on the skin. It has antiseptic and healing functions, since with its natural nutrients they help the regeneration of the cells of all layers of the skin. Anti-inflammatory, analgesic, antiviral, antitoxic. It can be used as a hair strengthener for its nutritional agents, as it provides softness, resistance and flexibility. It is a biogenic stimulant that activates and vivifies skin cells.
  • Bisabolol in particular alpha-bisabolol, is one of the main active ingredients of chamomile.
  • Chamomile ⁇ Matricaria Chamomilla is a medicinal plant traditionally used in medicine. This molecule is used in cosmetics in preparations for the care of sensitive skin, baby cosmetics, sunscreens and post-sunscreens, aftershaves and oral hygiene products, for its proven anti-inflammatory, healing and bacteriostatic properties.
  • Panthenol or provitamin B5 is a precursor to vitamin B5 (unstable in cosmetic products), it is beneficial for the skin, hair and nails.
  • the topical application accelerates the cellular regeneration of the skin and allows it to remain hydrated and elastic. It is a moisturizer that acts by moisturizing the hair, providing a shine coating to the fat-free hair fiber, penetrating through the cuticle to moisturize the cortex. This increases flexibility and
  • REPLACEMENT SHEET (Rule 26) hair manageability, improving resistance to mechanical stress. It also helps to provide volume and amplitude to the hair.
  • Actin is composed of actin oligopeptides with a molecular weight of less than 1500.
  • Actin is a structuring protein of living cells. In combination with certain algae extracts, it acts as a factor of nutrition and stimulation of the vitality of anagen hair bulbs, as a bio-conditioner for hair and scalp, as well as a bio-structuring and cohesion enhancer of the cuticle scales of the hair.
  • Glycerin is hygroscopic; It is a moisturizer that acts as a water reservoir, moisturizing the skin and hair. It is a long-lasting plasticizer, which improves the elasticity of the stratum corneum and decreases the roughness of the skin.
  • PEG-8 dimethicone meadowfoamate is a PEG-8 dimethicone grade ester. It has a polyoxyethylene group in a silicone structure, as well as a fatty group attached to the polyoxyethylene group. The presence of the meadowfoamate group in the ester increases the solubility of the ingredient, allowing better penetration into the hair. Repair the hair cuticle, increasing its strength. It has emollient and lubricating properties.
  • Fucus vesiclesus is a seaweed that is found in Seanam ⁇ n, purified and concentrated active ingredient, obtained by the biotransformation of fish. It acts as a factor of nutrition and stimulation of the vitality of anagen hair bulbs, as a bio-conditioner for hair and scalp, as well as a bio-structuring and cohesion enhancer of hair cuticle scales.
  • the Cod ⁇ um tomentosum is a green algae that synthesizes a sulfated heteropolysaccharide rich in glucuronic acid (marine beta-hydroxy acid) and in osmotic substances. It has an anti-aging and hydration action thanks to its
  • REPLACEMENT SHEET (Rule 26) Long-term water retention capacity.
  • the extract used in the present invention is composed of sulfated polysaccharides of an anionic nature, glucuronic acid, sugars, minerals and proteins.
  • sulfated polysaccharides keep water inside the epidermis, forming a barrier film to dehydration.
  • the minerals allow to maintain a balance of water between the extra and intracellular compartments.
  • glucuronic acid controls desquamation, increases cell cohesion between corneocytes and stimulates the formation of skin lipids.
  • the seawater used in the present application is groundwater that sprouts to the surface. It has a high concentration of minerals (calcium, magnesium, silicon) highlighting the presence in traces of elements such as magnesium, zinc and copper. Stimulates cell metabolism, promotes cohesion of the epidermis and stimulates cell synthesis. It has a protective action of the skin thanks to its antioxidant activity. It also acts as anti-inflammatory and anti-allergenic
  • Diazolidinylurea also known as 1,3- bis (hydroxymethyl) -1- (1, 3, -tris (hydroxymethyl) -2,5-dioxo-imidazolidin-4-yl) urea is an antimicrobial preservative widely used in cosmetic products.
  • PEG-60 hydrogenated castor oil is a solubilizer of ingredients difficult to incorporate into aqueous media.
  • Sodium polyacrylate is an ingredient that gives consistency to the product providing a light texture and easy absorption.
  • solvents useful in the formulation of the compositions of the invention are propanediol, propylene glycol and water.
  • compositions were evaluated with two efficacy tests: one in Vitro and one in Vivo.
  • the in Vitro test the anti-aging and antioxidant efficacy of cosmetic compositions on the scalp was evaluated.
  • the results obtained showed that these cosmetic compositions decrease cell proliferation, increasing the longevity of human neonatal keratinocytes 3 times compared to those not treated and increasing up to 50% in the case of adult human keratinocytes.
  • the in vitro test performed demonstrates a total antioxidant action in
  • REPLACEMENT SHEET (Rule 26) human keratinocyte, since it completely inhibits the formation of intracellular oxygen reactive species (ROS).
  • ROS oxygen reactive species

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition cosmétique de soin des cheveux et du cuir chevelu permettant d'augmenter la solidité, l'élasticité et la restructuration de la peau, ou de retarder la sénescence cellulaire du cuir chevelu, ou une combinaison des deux.
PCT/ES2013/070025 2012-01-23 2013-01-22 Composition cosmétique pour traiter les cheveux et le cuir chevelu WO2013110840A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201230086A ES2427423B1 (es) 2012-01-23 2012-01-23 Composición cosmética para tratar el cabello y el cuero cabelludo
ESP201230086 2012-01-23

Publications (1)

Publication Number Publication Date
WO2013110840A1 true WO2013110840A1 (fr) 2013-08-01

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PCT/ES2013/070025 WO2013110840A1 (fr) 2012-01-23 2013-01-22 Composition cosmétique pour traiter les cheveux et le cuir chevelu

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ES (1) ES2427423B1 (fr)
WO (1) WO2013110840A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111920726B (zh) * 2020-09-27 2023-01-10 广州德谷个人护理用品有限公司 一种多效快速头皮止痒的组合物、其制备方法及洗发水组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231877B1 (en) * 1998-07-03 2001-05-15 Lanatech Laboratoire Nature Et Technique Cosmetic composition exploiting synergistic radical scavenging effects
US20050048008A1 (en) * 2003-08-29 2005-03-03 Bioderm Research Antiaging Cosmetic Delivery Systems
EP1600143A1 (fr) * 2003-02-13 2005-11-30 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo PREPARATION DERMIQUE A USAGE EXTERNE CONTENANT UN SUCRE DERIVE DE LA a,a-TREHALOSE

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231877B1 (en) * 1998-07-03 2001-05-15 Lanatech Laboratoire Nature Et Technique Cosmetic composition exploiting synergistic radical scavenging effects
EP1600143A1 (fr) * 2003-02-13 2005-11-30 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo PREPARATION DERMIQUE A USAGE EXTERNE CONTENANT UN SUCRE DERIVE DE LA a,a-TREHALOSE
US20050048008A1 (en) * 2003-08-29 2005-03-03 Bioderm Research Antiaging Cosmetic Delivery Systems

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Publication number Publication date
ES2427423B1 (es) 2014-10-01
ES2427423A1 (es) 2013-10-30

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