WO2013094992A3 - 성장인자의 발치된 치아의 손상된 치주조직과 치수조직을 재생시키는 용도, 이 성장인자를 활성성분으로 함유하는 조성물 및 조직재생용 키트 - Google Patents

성장인자의 발치된 치아의 손상된 치주조직과 치수조직을 재생시키는 용도, 이 성장인자를 활성성분으로 함유하는 조성물 및 조직재생용 키트 Download PDF

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Publication number
WO2013094992A3
WO2013094992A3 PCT/KR2012/011136 KR2012011136W WO2013094992A3 WO 2013094992 A3 WO2013094992 A3 WO 2013094992A3 KR 2012011136 W KR2012011136 W KR 2012011136W WO 2013094992 A3 WO2013094992 A3 WO 2013094992A3
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WO
WIPO (PCT)
Prior art keywords
tissue
growth factor
kit
extracted tooth
active ingredient
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Application number
PCT/KR2012/011136
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English (en)
French (fr)
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WO2013094992A2 (ko
Inventor
김수홍
Original Assignee
(주) 코웰메디
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Application filed by (주) 코웰메디 filed Critical (주) 코웰메디
Publication of WO2013094992A2 publication Critical patent/WO2013094992A2/ko
Publication of WO2013094992A3 publication Critical patent/WO2013094992A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 발치된 치아의 재식립술에서 성장인자를 이용하여 치주인대와 치조골 및 치아의 백악질로 구성된 치주조직을 재생하고 발치된 치아의 치수조직을 재생시켜 발치된 치아를 정상 저작 기능을 하는 치아로 이용하도록 하는 BMPs의 용도와 이 BMPs를 활성성분으로 함유하는 조성물 및 키트에 관한 것이다.
PCT/KR2012/011136 2011-12-20 2012-12-20 성장인자의 발치된 치아의 손상된 치주조직과 치수조직을 재생시키는 용도, 이 성장인자를 활성성분으로 함유하는 조성물 및 조직재생용 키트 WO2013094992A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0138707 2011-12-20
KR20110138707 2011-12-20

Publications (2)

Publication Number Publication Date
WO2013094992A2 WO2013094992A2 (ko) 2013-06-27
WO2013094992A3 true WO2013094992A3 (ko) 2013-08-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/011136 WO2013094992A2 (ko) 2011-12-20 2012-12-20 성장인자의 발치된 치아의 손상된 치주조직과 치수조직을 재생시키는 용도, 이 성장인자를 활성성분으로 함유하는 조성물 및 조직재생용 키트

Country Status (1)

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WO (1) WO2013094992A2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104707180B (zh) * 2015-02-06 2017-01-25 福州大学 负载bmp丝素蛋白/胶原蛋白支架材料及其制备方法
CN105126175B (zh) * 2015-09-10 2019-02-12 南方医科大学南方医院 一种静电纺丝纤维可载药牙周组织再生材料及其制备方法
RU2680797C1 (ru) * 2018-05-22 2019-02-26 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ подготовки костной альвеолы к имплантации
AU2020330857B2 (en) * 2019-08-12 2023-07-13 Corneat Vision Ltd. Gingival graft
CN113041400B (zh) * 2019-08-31 2022-03-08 深圳市立心科学有限公司 可诱导骨生长的人工骨复合材料
RU2758903C1 (ru) * 2021-01-22 2021-11-02 Общество с ограниченной ответственностью "Профессорская клиника Едранова" Способ двухэтапной реконструкции альвеолярного гребня для установки дентальных имплантатов

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
KIM, JI-SOOK ET AL.: "Effects of bone morphogenetic protein on the healing of periodontium after tooth replantation of the rat", JOURNAL OF KOREAN ACADEMY OF PERIODONTOLOGY, vol. 32, 2002, pages 501 - 521 *
KINOSHITA, A. ET AL.: "Periodontal Regeneration by Application of Recombinant Human Bone Morphogenetic Protein-2 to Horizontal Circumferential Defects Created by Experimental periodontitis in Beagle Dogs", JOURNAL OF PERIODONTOLOGY, vol. 68, 1997, pages 103 - 109 *
LEE, SE JUN ET AL.: "The study on periodontal regeneration of replanted teeth following the application of rh-BMP-4", JOURNAL OF KOREAN ACADEMY OF OPERATIVE DENTISTRY, vol. 25, 2000, pages 170 - 179 *
RIPAMONTI, U. ET AL.: "Bone morphogenetic proteins induce periodontal regeneration in the baboon(Papio Ursinus)", JOURNAL OF PERIODONTAL RESEARCH, vol. 29, 1994, pages 439 - 445, XP055079584 *
RIPAMONTI, U. ET AL.: "Periodontal tissue regeneration by combined applications of recombinant human osteogenic protein- and bone morphogenetic protein-2. A pilot study in Chacma baboons (Papio ursinus)", EUROPEAN JOURNAL OF ORAL SCIENCES, vol. 109, 2001, pages 241 - 248 *
SLOAN, A.J. ET AL.: "Stimulation of the rat dentine-pulp complex by bone morphogenetic protein-7 in vitro", ARCHIVES OF ORAL BIOLOGY, vol. 45, 2000, pages 173 - 177, XP055080075 *
TALWAR R. ET AL.: "Effects of carrier release kinetics on bone morphogenetic protein-2- induced periodontal regeneration in vivo", JOURNAL OF CLINICAL PERIODONTOLOGY, vol. 28, no. 4, 2001, pages 340 - 347, XP055080077 *
ZHANG, W. ET AL.: "Vital Pulp Therapy-Current Progress of Dental Pulp Regeneration and Revascularization", INTERNATIONAL JOURNAL OF DENTISTRY, vol. 2010, 2010, pages 1 - 9, XP003031285 *

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