WO2013089449A1 - 홍삼 먹인 달팽이 점액을 함유하는 화장료 조성물 및 그 제조방법 - Google Patents

홍삼 먹인 달팽이 점액을 함유하는 화장료 조성물 및 그 제조방법 Download PDF

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Publication number
WO2013089449A1
WO2013089449A1 PCT/KR2012/010836 KR2012010836W WO2013089449A1 WO 2013089449 A1 WO2013089449 A1 WO 2013089449A1 KR 2012010836 W KR2012010836 W KR 2012010836W WO 2013089449 A1 WO2013089449 A1 WO 2013089449A1
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WO
WIPO (PCT)
Prior art keywords
cosmetic composition
snail
red ginseng
skin
comparative
Prior art date
Application number
PCT/KR2012/010836
Other languages
English (en)
French (fr)
Korean (ko)
Inventor
박성민
박성노
윤미영
박지영
Original Assignee
주식회사 코씨드바이오팜
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 주식회사 코씨드바이오팜 filed Critical 주식회사 코씨드바이오팜
Priority to CN201280065814.2A priority Critical patent/CN104254318A/zh
Publication of WO2013089449A1 publication Critical patent/WO2013089449A1/ko
Priority to PH12014501342A priority patent/PH12014501342A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • the present invention relates to a cosmetic composition containing snail mucus, and more particularly to a cosmetic composition containing snail mucus derived from a snail fed red ginseng.
  • wound healing involves a complex process that involves inflammation, cell proliferation, cell migration, blood vessel proliferation, and cell matrix formation. These steps are continuous with some overlap without clear distinction, and the rate and extent of healing varies according to tissue and wound healing method. That is, there are various forms of skin wounds, and each wound has anatomical, physiological, pathological and microbiological factors that are related to each other according to their type. All these factors are involved in the wound healing process, but the basics of the process are as follows.
  • Johnston divides it into four phases: inflammatory, debride, repair, and mature. It should be noted that the characteristic of the wound healing process is that the cycle of abnormal cycles is continuous.
  • Mucin is composed of mucin, and mucin is composed of chondroitin sulfate.
  • Major nutrients are known as proteins (54.29%), lipids (4.18%), carbohydrates (30.45%), and ash (4.07%).
  • Allantoin the main ingredient of snail mucus, has a soothing effect on skin and pore shrinkage. Glycolic acid prevents skin trouble, and collagen and elastin maintain skin elasticity. It is known.
  • Korean Patent Publication No. 10-1995-0002741 (1995. 02. 16) relates to a "method of manufacturing cosmetics using a mucin component extracted from a snail", which is washed in clean water After immersing in hot water containing salt to completely remove impurities contained in the snail, the liquid mucin components are collected from the snails, and the collected mucin components are heated to evaporate moisture to extract pure mucin components and extracted mucin. It describes a cosmetic produced by mixing the ingredients in the mixing process of the basic ingredients in the manufacturing process of the cosmetic.
  • red ginseng refers to processed ginseng made by repeating the steaming process of steaming and drying steamed ginseng without peeling it.
  • Red ginseng is characterized by a very high content of physiologically active substance per gram of moisture due to evaporation of moisture as well as a visual difference of light yellowish brown or light reddish brown. It is known that red ginseng converts saponin glycosides to saponins during steaming to increase the concentration of saponins and to increase the species to 32 species.
  • the present invention is to combine the red ginseng and snail mucus having the excellent efficacy as described above, to be applied to skin cosmetics and to provide a cosmetic composition derived from a natural material harmless to the human body.
  • the snail mucus serving as a main component is a mucus obtained from a snail fed red ginseng.
  • Snail mucus obtained from the snail fed red ginseng showed better cell activity and skin moisturizing, atopic skin regeneration effect than the existing snail mucus, from which can have an excellent wound healing and skin regeneration effect.
  • the cosmetic composition of the present invention is excellent in skin moisturizing effect, cell activation effect, atopy improvement effect, so very excellent skin regeneration and wound healing effect, for skin regeneration, wound healing, skin irritation relief, atopic improvement, Can be used for skin moisturizing.
  • the formulation of the cosmetic composition of the present invention is preferably a lotion, gel, water-soluble liquid, cream, essence, oil-in-water (O / W) type and water-in-oil (W / O) type emulsion, ointment base cosmetic formulation, water
  • O / W oil-in-water
  • W / O water-in-oil
  • ointment base cosmetic formulation water
  • the present invention uses the snail mucus obtained from the snail fed red ginseng, it is possible to prepare a cosmetic composition excellent in safety because it is harmless to the human body.
  • the present invention can provide a cosmetic composition exhibiting excellent skin rejuvenation effect as well as excellent skin regeneration effect using the snail mucus obtained from the snail fed red ginseng, has an irritating effect.
  • red ginseng Five-year-old red ginseng was selected as a sample, thoroughly washed and ground, and then fed to the snail by adding 10% (w / w) to the general snail feed.
  • the snail for the experiment was Achatina fulica or Helix pomatia species, selected only for snails grown for 5 to 6 months, and 5 to 10 cm in size, preferably 6 to 8 cm. Do.
  • the feeding of red ginseng to the selected snails continued for 1 to 4 times for 150 to 180 days.
  • the snails which had eaten red ginseng, were washed in running water, and only similar sizes (6 ⁇ 8cm) were selected, sterilized thoroughly with 70% ethanol, and weighed to obtain accurate mucus.
  • Comparative Preparation Example 1 A mixed solution of snail mucus not fed red ginseng of Comparative Preparation Example 1 and red ginseng extract of Comparative Preparation Example 2 was prepared. Comparative Preparation Example 1 and Comparative Preparation Example 2 were each added 50% (w / w).
  • HDF Human dermal fibroblast
  • SLS is a substance that is used as a criterion for evaluation of skin irritation based on cosmetics, and is a substance that binds to cell membranes to inhibit cell metabolism and destroys cell membranes to cause skin irritation.
  • the phase 'B' recorded in Table 4 was heated and stored at 70 ° C., and preliminary emulsification was added to the stored phase 'B' by adding the 'ga' phase, and then uniformly emulsified with a homomixer, and then gradually cooled. Creams (Examples and Comparative Examples 1 to 4) were prepared.
  • Moisturizing of the test site of the subject before (0 week), 2 weeks and 4 weeks after product application was measured using a skin moisture meter (Corneometer). There were no adverse events in all subjects who participated in the 4-week trial.
  • the skin moisture meter measures the capacity of the minute current that is conducted to the sensor embedded in the probe's head when the probe is in contact with the surface of the skin and indicates the moisture content. This means a lot.
  • wound shrinkage was obtained by digitally imaging wound areas at 3, 7, 9, 11, and 14 days after 1 day in the autopsy group with an initial wound area of 100.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PCT/KR2012/010836 2011-12-13 2012-12-13 홍삼 먹인 달팽이 점액을 함유하는 화장료 조성물 및 그 제조방법 WO2013089449A1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201280065814.2A CN104254318A (zh) 2011-12-13 2012-12-13 含有用红参饲喂的蜗牛粘液的化妆品组合物及其制造方法
PH12014501342A PH12014501342A1 (en) 2011-12-13 2014-06-13 Cosmetic composition containing the slime of snails fed with red ginseng and method for manufacturing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0133374 2011-12-13
KR1020110133374A KR101208012B1 (ko) 2011-12-13 2011-12-13 홍삼 먹인 달팽이 점액을 함유하는 화장료 조성물 및 그 제조방법

Publications (1)

Publication Number Publication Date
WO2013089449A1 true WO2013089449A1 (ko) 2013-06-20

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PCT/KR2012/010836 WO2013089449A1 (ko) 2011-12-13 2012-12-13 홍삼 먹인 달팽이 점액을 함유하는 화장료 조성물 및 그 제조방법

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KR (1) KR101208012B1 (zh)
CN (1) CN104254318A (zh)
PH (1) PH12014501342A1 (zh)
WO (1) WO2013089449A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104434719A (zh) * 2014-11-04 2015-03-25 广州卡迪莲化妆品有限公司 一种蜗牛分泌物滤液在提升彩妆类产品贴肤性能中的应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104887596A (zh) * 2014-03-05 2015-09-09 广州澳医生物科技有限公司 一种全效修复的蜗牛原液及其制备方法
CN103860451B (zh) * 2014-04-01 2015-12-02 广东伊茗药业有限公司 一种含有蜗牛黏液提取物的功效性护肤品及制备方法
CN103976933B (zh) * 2014-05-28 2016-06-29 北京中亿世联科技发展有限公司 含蜗牛粘液提取物的组合物及其制造工艺
KR101649939B1 (ko) * 2014-09-24 2016-08-22 (주)차모스코스메틱 생광석을 먹인 달팽이 점액의 제조방법 및 이를 함유하는 화장료 조성물
KR101728686B1 (ko) * 2015-03-31 2017-04-21 주식회사 크릴랜드 베리과 열매를 섭취한 달팽이 점액을 함유하는 화장료 조성물 및 그의 제조방법
KR101802963B1 (ko) * 2016-02-26 2017-11-29 농업회사법인 우리엘바이오 주식회사 발효 추출물을 이용한 화장료 조성물
CN106727224A (zh) * 2016-12-16 2017-05-31 常州市鼎日环保科技有限公司 一种保湿防皲裂护手霜的制备方法

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KR960012607B1 (ko) * 1993-06-18 1996-09-23 엘지화학 주식회사 피부건조방지용 보습화장료 조성물
KR20010054526A (ko) * 1999-12-07 2001-07-02 금동우 달팽이 생진액을 이용한 화장료 제조방법
KR20030007999A (ko) * 2001-07-12 2003-01-24 신원의 천연소재를 이용한 마사지 크림 및 그의 제조 방법
US20100233111A1 (en) * 2008-04-06 2010-09-16 William Wang Gastropod biological fluid, method of making and refining and use

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CN1112831A (zh) * 1994-05-30 1995-12-06 乌力吉 含蜗牛提取液的长效多功能营养护肤水及其制法
KR101098400B1 (ko) 2010-08-31 2011-12-26 주식회사 코씨드바이오팜 홍삼 먹인 달팽이 점액의 제조방법 및 이를 함유하는 화장료 조성물

Patent Citations (4)

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KR960012607B1 (ko) * 1993-06-18 1996-09-23 엘지화학 주식회사 피부건조방지용 보습화장료 조성물
KR20010054526A (ko) * 1999-12-07 2001-07-02 금동우 달팽이 생진액을 이용한 화장료 제조방법
KR20030007999A (ko) * 2001-07-12 2003-01-24 신원의 천연소재를 이용한 마사지 크림 및 그의 제조 방법
US20100233111A1 (en) * 2008-04-06 2010-09-16 William Wang Gastropod biological fluid, method of making and refining and use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104434719A (zh) * 2014-11-04 2015-03-25 广州卡迪莲化妆品有限公司 一种蜗牛分泌物滤液在提升彩妆类产品贴肤性能中的应用
CN104434719B (zh) * 2014-11-04 2018-01-23 广州卡迪莲化妆品有限公司 一种蜗牛分泌物滤液在提升彩妆类产品贴肤性能中的应用

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PH12014501342B1 (en) 2014-09-15
PH12014501342A1 (en) 2014-09-15
KR101208012B1 (ko) 2012-12-04
CN104254318A (zh) 2014-12-31

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