WO2013042413A1 - Dispositif de traitement d'image radiographique en mouvement, dispositif de prise d'image radiographique en mouvement, système de prise d'image radiographique en mouvement, procédé de prise d'image radiographique en mouvement, et programme de prise d'image radiographique en mouvement - Google Patents

Dispositif de traitement d'image radiographique en mouvement, dispositif de prise d'image radiographique en mouvement, système de prise d'image radiographique en mouvement, procédé de prise d'image radiographique en mouvement, et programme de prise d'image radiographique en mouvement Download PDF

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Publication number
WO2013042413A1
WO2013042413A1 PCT/JP2012/065788 JP2012065788W WO2013042413A1 WO 2013042413 A1 WO2013042413 A1 WO 2013042413A1 JP 2012065788 W JP2012065788 W JP 2012065788W WO 2013042413 A1 WO2013042413 A1 WO 2013042413A1
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WIPO (PCT)
Prior art keywords
interest
region
radiation
moving image
unit
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PCT/JP2012/065788
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English (en)
Japanese (ja)
Inventor
北野　浩一
岩切　直人
西納　直行
中津川　晴康
大田　恭義
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富士フイルム株式会社
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Publication of WO2013042413A1 publication Critical patent/WO2013042413A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4225—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using image intensifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/46—Arrangements for interfacing with the operator or the patient
    • A61B6/467—Arrangements for interfacing with the operator or the patient characterised by special input means
    • A61B6/469—Arrangements for interfacing with the operator or the patient characterised by special input means for selecting a region of interest [ROI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/486—Diagnostic techniques involving generating temporal series of image data
    • A61B6/487—Diagnostic techniques involving generating temporal series of image data involving fluoroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
    • A61B6/542—Control of apparatus or devices for radiation diagnosis involving control of exposure

Definitions

  • the present invention relates to a radiation moving image processing apparatus, a radiation moving image capturing apparatus, a radiation moving image capturing system, a radiation moving image capturing method, and a radiation moving image capturing program.
  • radiation detectors such as FPD (Flat Panel Detector) that can arrange radiation sensitive layers on TFT (Thin Film Transistor) active matrix substrates and convert radiation dose into digital data (electrical signals) (referred to as “electronic cassettes”)
  • FPD Fluor Deposition Detector
  • TFT Thin Film Transistor
  • electrospray cassettes a radiation image capturing apparatus that captures a radiation image represented by the amount of irradiated radiation using this radiation detector has been put into practical use.
  • the radiation dose is, for example, interchangeably converted into a light emission amount and then converted into an electric signal, and then a direct conversion method in which the radiation dose is directly converted into an electric signal, and is selected as appropriate. Adopted.
  • a region of interest (ROI: Region Of Interest) is specified and ABC control is performed on the region of interest, whereby an image that is easy for a doctor to interpret can be obtained.
  • the region of interest may be set by an operation input or the like, but a technique for specifying the region of interest based on a captured image has also been proposed.
  • the ROI based on the magnitude of the density value feature amount between a plurality of images taken at different times. Specifically, the difference image of two images is divided into a plurality of blocks, the sum of squares of the density values of each block is calculated, and a block whose calculated sum of squares is equal to or greater than a threshold is extracted as an ROI. Has been proposed.
  • ABC control is performed in which a region of interest is set, a plurality of regions of interest are generated by dividing the set region of interest into a plurality, and weighted for each region of interest. Has been proposed to do.
  • the ROI based on the magnitude of the density value feature quantity.
  • the density value feature quantity depends on the shooting conditions such as ABC control. Since there is a possibility, there is room for improvement in order to extract an appropriate ROI.
  • the present invention has been made in consideration of the above-described facts, and even when there are a plurality of attention objects, a radiation moving image processing apparatus, a radiation moving image capturing apparatus, and a radiation moving image capturing capable of easily setting an appropriate region of interest.
  • a radiation moving image processing apparatus for processing radiation moving image signals
  • a radiation moving image capturing apparatus for capturing medical images
  • a radiation moving image capturing program for capturing medical images.
  • the radiographic imaging device is configured to provide a plurality of radiation doses that have been irradiated from a radiation irradiation unit that irradiates radiation with radiation irradiation energy corresponding to a set value that has been set and have passed through a subject.
  • One frame of still image information is received based on the gradation signal output from the radiation image capturing unit that outputs the gradation signal corresponding to the amount of radiation received for each pixel.
  • An image information generation unit configured to generate moving image information by combining a plurality of frames of the still image information continuously, and the still image information of each frame in the moving image information generated by the image information generation unit And calculating a difference between frames for the structure detected by the detection unit and the structure detected by the detection unit, and the calculated difference is a predetermined value.
  • the radiation irradiating unit emits radiation with the radiation irradiation energy corresponding to the set setting value, and the radiation image capturing unit irradiates from the radiation irradiating unit.
  • the radiation detector passes through the subject and is irradiated on the radiation detector.
  • the radiation detector outputs a gradation signal corresponding to the amount of radiation received for each pixel when the radiation is irradiated.
  • the image information generating unit generates still image information based on the gradation signal output from the radiographic image capturing unit, and generates moving image information by continuously combining the still image information.
  • the detection unit detects the structure of interest based on the still image information of each frame in the moving image information generated by the image information generation unit. That is, a structure that is a candidate for a region of interest is detected.
  • the region-of-interest setting unit calculates a difference between frames for the structure detected by the detection unit, and a structure having the calculated difference equal to or greater than a predetermined value is set as the region of interest.
  • a plurality of structures having a difference of a predetermined value or more as a region of interest are set.
  • the region-of-interest setting unit may calculate a difference in size of the structure between frames. This makes it possible to set a region of interest with movement.
  • At least one frame of the frame is based on the gradation signal in the region of interest set by the region-of-interest setting unit.
  • a control unit that feedback-controls the set value of the radiation energy irradiated from the radiation irradiation unit under a predetermined condition so that the calculated value of the gradation signal in a part of the still image information falls within a predetermined range. May be further provided. As a result, it is possible to appropriately control the radiation dose irradiated to the set region of interest.
  • the control unit when the plurality of regions of interest are set stepwise by the region-of-interest setting unit, the control unit, among the plurality of regions of interest, Feedback control of the set value of the radiation energy irradiated from the radiation irradiation unit under a predetermined condition so that the calculated value of the gradation signal in the initially set region of interest becomes a value in a predetermined range. You may make it do.
  • the control unit is newly set out of the plurality of regions of interest when the plurality of regions of interest are set in stages by the region of interest setting unit.
  • the set value of the radiation energy irradiated from the radiation irradiation unit may be feedback-controlled under a predetermined condition so that the calculated value of the gradation signal in the region of interest is a value in a predetermined range. Good.
  • the gradation signal in the non-interest region other than the region of interest set by the region of interest setting unit is represented.
  • the region of interest information is irreversibly compressed at a predetermined compression rate
  • the region of interest setting unit sets a plurality of regions of interest
  • the region of interest information is compressed at a compression rate higher than the predetermined compression rate. You may make it further provide the compression part which compresses irreversibly. Thereby, the slew rate at the time of information transfer can be improved.
  • the compression unit when the plurality of regions of interest are set by the region-of-interest setting unit, the compression unit performs gradation in the region of interest having a low predetermined weight.
  • the region-of-interest information representing the signal may be further irreversibly compressed at a lower compression rate than the non-region-of-interest information.
  • the moving image information A frame rate control unit may be further provided that performs control so that the frame rate is reduced and displayed on the display unit.
  • the moving image information A frame rate control unit that controls to increase the frame rate and display the frame rate on the display unit may be further provided. That is, when the frame rate is lowered, the slew rate at the time of information transfer can be improved. Conversely, when the frame rate is raised, the region of interest can be observed in detail.
  • the region of interest set by the region-of-interest setting unit can be discriminated based on the moving image information. You may make it further provide the display control part which controls to display a moving image on a display part. As a result, the identified region of interest can be displayed on the display unit.
  • the radiation amount irradiated from the radiation irradiation unit that irradiates the radiation with the radiation irradiation energy corresponding to the set value that has been set and passed through the subject is provided with a plurality of pixels.
  • the radiation irradiating unit that irradiates the radiation with the radiation irradiation energy corresponding to the set set value
  • the radiation moving image photographing apparatus according to the eleventh aspect of the present invention. It is good also as a radiation animation photographing system.
  • the radiation moving image capturing method irradiates the subject with radiation from the radiation irradiating unit toward the subject with radiation energy corresponding to the set value, and passes through the subject.
  • the amount is received by a radiation detector having a plurality of pixels, and one frame of still image information is generated based on a gradation signal corresponding to the amount of radiation received for each pixel, and the still image information is continuously generated.
  • a plurality of frames are combined to generate moving image information, a target structure is detected based on the still image information of each frame in the generated moving image information, and a difference between frames is detected for the detected structure And the structure having the calculated difference equal to or greater than a predetermined value is set as a region of interest, and when there are a plurality of structures exceeding the predetermined value or the region of interest is set When detecting the predetermined value or more of the structure, the multiple sets the predetermined value or more of the structure as the region of interest.
  • radiation is irradiated toward the subject with radiation energy corresponding to the set value that has been set, and the amount of radiation that has passed through the subject is determined using a plurality of pixels.
  • still image information is generated based on a gradation signal corresponding to the radiation dose received for each pixel of the radiation detector, and moving image information is obtained by combining a plurality of frames of the still image information of one frame continuously. Generate.
  • the structure of interest is detected based on the still image information of each frame in the generated moving image information. That is, a structure that is a candidate for a region of interest is detected.
  • the region of interest in the video is a moving structure. Therefore, a difference between frames is calculated for the detected structure, and a structure having the calculated difference equal to or greater than a predetermined value is set as a region of interest.
  • a plurality of structures having a difference between frames equal to or greater than a predetermined value are set as regions of interest.
  • a difference in size of the structure between frames may be calculated. This makes it possible to set a region of interest with movement.
  • the thirteenth or fourteenth aspect of the present invention a part of the still image information of at least one frame based on the gradation signal in the set region of interest.
  • the set value of the radiation energy irradiated from the radiation irradiating unit may be further feedback controlled under a predetermined condition so that the calculated value of the gradation signal in the above becomes a value in a predetermined range.
  • the first region of interest set in the region of interest is set first.
  • the set value of the radiation energy emitted from the radiation irradiating unit may be feedback controlled under a predetermined condition so that the calculated value of the gradation signal falls within a predetermined range.
  • the gradation signal calculation in the region of interest newly set out of the plurality of regions of interest is performed.
  • the set value of the radiation energy irradiated from the radiation irradiation unit may be feedback-controlled under a predetermined condition so that the value is in a predetermined range.
  • non-region-of-interest information representing a gradation signal in a non-region of interest other than the set region of interest is predetermined.
  • the non-region-of-interest information may be irreversibly compressed at a compression rate higher than the predetermined compression rate.
  • the region-of-interest information representing the gradation signal in the region of interest having a low predetermined weight is obtained. You may make it compress more irreversibly by a compression rate lower than non-region-of-interest information.
  • the frame rate of the moving image information is lowered as the number of set regions of interest increases. You may make it control further so that it may display on a display part.
  • the frame rate of the moving image information is increased as the number of set regions of interest increases. You may make it control further so that it may display on a display part. That is, when the frame rate is lowered, the slew rate at the time of information transfer can be improved. Conversely, when the frame rate is raised, the region of interest can be observed in detail.
  • the moving image based on the moving image information is displayed on the display unit so that the set region of interest can be discriminated. Further control may be performed as described above. As a result, the identified region of interest can be displayed on the display unit.
  • the radiation moving image photographing program is for causing a computer to function as each part constituting the radiation moving image processing apparatus according to any one of the first to tenth aspects of the present invention. .
  • the computer can function as each part constituting the radiation moving image processing apparatus according to any one of the first to tenth aspects of the present invention, the same as the invention according to the first aspect of the present invention.
  • an appropriate region of interest can be easily set even when there are a plurality of attention objects.
  • 4 is a flowchart illustrating an image processing control routine according to the embodiment. It is a flowchart which shows the structure detection and region-of-interest extraction routine which concern on embodiment. It is a figure for demonstrating the detection of a structure. It is a figure for demonstrating specification of a region of interest.
  • FIG. 1 is a schematic configuration diagram of a radiation information system (hereinafter referred to as “RIS” (Radiology Information System)) 10 according to the present embodiment.
  • the RIS 10 can shoot moving images in addition to still images.
  • the definition of a moving image means that still images are displayed one after another at a high speed and recognized as a moving image.
  • the still image is shot, converted into an electric signal, transmitted, and the still image is reproduced from the electric signal. This process is repeated at high speed. Therefore, the so-called “frame advance” in which the same area (part or all) is photographed a plurality of times within a predetermined time and continuously reproduced depending on the degree of the “high speed” is also included in the moving image.
  • frame advance in which the same area (part or all) is photographed a plurality of times within a predetermined time and continuously reproduced depending on the degree of the “high speed” is also included in the moving image.
  • the RIS 10 is a system for managing information such as medical appointments and diagnosis records in the radiology department, and constitutes a part of a hospital information system (hereinafter referred to as “HIS” (Hospital Information System)).
  • HIS Hospital Information System
  • the RIS 10 includes a plurality of radiographic imaging systems installed individually in a plurality of imaging request terminal devices (hereinafter referred to as “terminal devices”) 12, a RIS server 14, and a radiographic room (or operating room) in a hospital.
  • terminal devices hereinafter referred to as “terminal devices”
  • RIS server a radiographic room (or operating room) in a hospital.
  • imaging system which are connected to an in-hospital network 18 composed of a wired or wireless LAN (Local Area Network) or the like.
  • the hospital network 18 is connected to an HIS server (not shown) that manages the entire HIS.
  • the radiographic image capturing system 16 may be a single unit or three or more facilities. In FIG. 1, the radiographic image capturing system 16 is installed for each radiographing room. An imaging system 16 may be arranged.
  • the terminal device 12 is used by doctors and radiographers to input and view diagnostic information and facility reservations, and radiographic image capturing requests and imaging reservations are performed via the terminal device 12.
  • Each terminal device 12 includes a personal computer having a display device, and is capable of mutual communication via the RIS server 14 and the hospital network 18.
  • the RIS server 14 receives an imaging request from each terminal device 12 and manages a radiographic imaging schedule in the imaging system 16, and includes a database 14A.
  • the database 14A was photographed in the past as attribute information (name, gender, date of birth, age, blood type, weight, patient ID (Identification), etc.), medical history, medical history of the patient as the subject.
  • Information related to the patient such as a radiographic image, information related to the electronic cassette 20 used in the imaging system 16, such as an identification number (ID information), model, size, sensitivity, start date of use, number of times of use, etc.
  • ID information an identification number
  • model e.g., model, size, sensitivity, start date of use, number of times of use, etc.
  • an environment in which a radiographic image is taken using the electronic cassette 20 that is, an environment in which the electronic cassette 20 is used (for example, a radiographic room or an operating room).
  • medical-related data managed by medical institutions is stored almost permanently, and when necessary, a system (sometimes referred to as a “medical cloud”) that instantly retrieves data from the required location can be used outside the hospital. You may make it acquire the past personal information etc. of a patient (subject) from a server.
  • a system sometimes referred to as a “medical cloud”
  • the imaging system 16 captures a radiographic image by an operation of a doctor or a radiographer according to an instruction from the RIS server 14.
  • the imaging system 16 is a radiation generator that irradiates a subject with radiation X having a dose according to irradiation conditions from a radiation irradiation source 22A that emits radiation X under the control of a radiation irradiation control unit 22 (see FIG. 4). 24 and a radiation detector 26 (see FIG. 3) that generates radiation by absorbing the radiation X that has passed through the region to be imaged of the subject and generates image information indicating a radiation image based on the amount of the generated charge.
  • a built-in electronic cassette 20, a cradle 28 for charging a battery built in the electronic cassette 20, and a console 30 for controlling the electronic cassette 20 and the radiation generator 24 are provided.
  • the console 30 acquires various types of information included in the database 14A from the RIS server 14 and stores them in an HDD 88 (see FIG. 4), which will be described later, and uses the information as necessary to use the electronic cassette 20 and the radiation generator 24. Control.
  • FIG. 2 shows an example of the arrangement state of each device in the radiation imaging room 32 of the imaging system 16 according to the present embodiment.
  • the radiation imaging room 32 there are a standing table 34 used when performing radiography in a standing position and a prone table 36 used when performing radiation imaging in a lying position.
  • the space in front of the standing table 34 is set as the imaging position of the subject 38 when performing radiography in the standing position, and the upper space of the prone table 36 is used in performing radiography in the prone position. This is the imaging position of the subject 40.
  • the standing table 34 is provided with a holding unit 42 that holds the electronic cassette 20, and the electronic cassette 20 is held by the holding unit 42 when a radiographic image is taken in the standing position.
  • a holding unit 44 that holds the electronic cassette 20 is provided in the lying position table 36, and the electronic cassette 20 is held by the holding unit 44 when a radiographic image is taken in the lying position.
  • the radiation irradiation source 22A is arranged around a horizontal axis in order to enable radiation imaging in a standing position and in a supine position by radiation from a single radiation irradiation source 22A.
  • the support moving mechanism 46 is supported so as to be rotatable in the direction (arrow A in FIG. 2), movable in the vertical direction (arrow B in FIG. 2), and further movable in the horizontal direction (arrow C in FIG. 2). Is provided.
  • a drive source for moving (including turning) the radiation irradiation source 22A in the directions of arrows A to C in FIG. 2 is built in the support moving mechanism 46, and is not shown here.
  • the cradle 28 is formed with an accommodating portion 28A capable of accommodating the electronic cassette 20.
  • the built-in battery is charged in a state of being accommodated in the accommodating portion 28A of the cradle 28.
  • the electronic cassette 20 is taken out of the cradle 28 by a radiographer or the like, and the photographing posture is established. If it is in the upright position, it is held in the holding part 42 of the standing table 34, and if it is in the upright position, it is held in the holding part 44 of the standing table 36.
  • various kinds of information are transmitted by wireless communication between the radiation generator 24 and the console 30 and between the electronic cassette 20 and the console 30. Send and receive (details will be described later).
  • the electronic cassette 20 is not used only in the state of being held by the holding portion 42 of the standing base 34 or the holding portion 44 of the prone position base 36. When photographing, it can be used in a state where it is not held by the holding unit.
  • FIG. 3 is a schematic cross-sectional view schematically showing the configuration of the three pixel portions of the radiation detector 26 provided in the electronic cassette 20.
  • the radiation detector 26 has a signal output unit 52, a sensor unit 54 (TFT substrate 74), and a scintillator 56 sequentially stacked on an insulating substrate 50.
  • the sensor unit 54 constitutes a pixel group of the TFT substrate 74. That is, the plurality of pixels are arranged in a matrix on the substrate 50, and the signal output unit 52 and the sensor unit 54 in each pixel are configured to overlap each other.
  • An insulating film 53 is interposed between the signal output unit 52 and the sensor unit 54.
  • the scintillator 56 is formed on the sensor unit 54 via a transparent insulating film 58, and forms a phosphor that emits light by converting radiation incident from above (opposite side of the substrate 50) or below into light. It is what. Providing such a scintillator 56 absorbs radiation transmitted through the subject and emits light.
  • the wavelength range of light emitted by the scintillator 56 is preferably in the visible light range (wavelength 360 nm to 830 nm), and in order to enable monochrome imaging by the radiation detector 26, the wavelength range of green is included. Is more preferable.
  • the phosphor used in the scintillator 56 preferably contains cesium iodide (CsI) when imaging using X-rays as radiation, and has an emission spectrum of 400 nm to 700 nm upon X-ray irradiation. It is particularly preferable to use CsI (Tl) (cesium iodide with thallium added). Note that the emission peak wavelength of CsI (Tl) in the visible light region is 565 nm.
  • CsI cesium iodide
  • the sensor unit 54 includes an upper electrode 60, a lower electrode 62, and a photoelectric conversion film 64 disposed between the upper and lower electrodes.
  • the photoelectric conversion film 64 is made of an organic photoelectric conversion material that generates charges by absorbing light emitted from the scintillator 56.
  • the upper electrode 60 Since it is necessary for the upper electrode 60 to cause the light generated by the scintillator 56 to enter the photoelectric conversion film 64, it is preferable that the upper electrode 60 be made of a conductive material that is transparent at least with respect to the emission wavelength of the scintillator 56. It is preferable to use a transparent conductive oxide (TCO) having a high transmittance for visible light and a small resistance value. Although a metal thin film such as Au can be used as the upper electrode 60, TCO is preferable because it tends to increase the resistance value when it is desired to obtain a transmittance of 90% or more.
  • TCO transparent conductive oxide
  • the upper electrode 60 may have a single configuration common to all pixels, or may be divided for each pixel.
  • the photoelectric conversion film 64 includes an organic photoelectric conversion material, absorbs light emitted from the scintillator 56, and generates electric charge according to the absorbed light.
  • the photoelectric conversion film 64 including the organic photoelectric conversion material has a sharp absorption spectrum in the visible region, and electromagnetic waves other than light emitted by the scintillator 56 are hardly absorbed by the photoelectric conversion film 64, and X-rays are obtained.
  • the noise generated by the radiation such as being absorbed by the photoelectric conversion film 64 can be effectively suppressed.
  • the organic photoelectric conversion material constituting the photoelectric conversion film 64 is preferably such that its absorption peak wavelength is closer to the emission peak wavelength of the scintillator 56 in order to absorb light emitted by the scintillator 56 most efficiently.
  • the absorption peak wavelength of the organic photoelectric conversion material matches the emission peak wavelength of the scintillator 56, but if the difference between the two is small, the light emitted from the scintillator 56 can be sufficiently absorbed.
  • the difference between the absorption peak wavelength of the organic photoelectric conversion material and the emission peak wavelength with respect to the radiation of the scintillator 56 is preferably within 10 nm, and more preferably within 5 nm.
  • Examples of the organic photoelectric conversion material that can satisfy such conditions include quinacridone organic compounds and phthalocyanine organic compounds.
  • quinacridone organic compounds since the absorption peak wavelength in the visible region of quinacridone is 560 nm, if quinacridone is used as the organic photoelectric conversion material and CsI (Tl) is used as the material of the scintillator 56, the difference in peak wavelength can be made within 5 nm. Thus, the amount of charge generated in the photoelectric conversion film 64 can be substantially maximized.
  • the sensor unit 54 constituting each pixel only needs to include at least the lower electrode 62, the photoelectric conversion film 64, and the upper electrode 60.
  • the electron blocking film 66 and the hole blocking film are used. It is preferable to provide at least one of 68, and it is more preferable to provide both.
  • the electron blocking film 66 can be provided between the lower electrode 62 and the photoelectric conversion film 64.
  • a bias voltage is applied between the lower electrode 62 and the upper electrode 60, electrons are transferred from the lower electrode 62 to the photoelectric conversion film 64. It is possible to suppress the dark current from increasing due to the injection of.
  • An electron donating organic material can be used for the electron blocking film 66.
  • the hole blocking film 68 can be provided between the photoelectric conversion film 64 and the upper electrode 60. When a bias voltage is applied between the lower electrode 62 and the upper electrode 60, the hole blocking film 68 is transferred from the upper electrode 60 to the photoelectric conversion film 64. It is possible to suppress the increase in dark current due to the injection of holes.
  • An electron-accepting organic material can be used for the hole blocking film 68.
  • the signal output unit 52 corresponds to the lower electrode 62, a capacitor 70 that accumulates the electric charge transferred to the lower electrode 62, and a field effect thin film transistor (Thin) that converts the electric charge accumulated in the capacitor 70 into an electric signal and outputs it.
  • Film-Transistor (hereinafter sometimes simply referred to as a thin film transistor) 72 is formed.
  • the region in which the capacitor 70 and the thin film transistor 72 are formed has a portion that overlaps the lower electrode 62 in plan view. With this configuration, the signal output unit 52 and the sensor unit 54 in each pixel are thick. There will be overlap in the vertical direction. In order to minimize the plane area of the radiation detector 26 (pixel), it is desirable that the region where the capacitor 70 and the thin film transistor 72 are formed is completely covered with the lower electrode 62.
  • FIG. 4 is a control block diagram of the imaging system 16 according to the present embodiment.
  • the console 30 is configured as a server computer, and includes a display 80 that displays an operation menu, a captured radiographic image, and the like, and a plurality of keys, and an operation panel on which various information and operation instructions are input. 82.
  • the console 30 includes a CPU 84 that controls the operation of the entire apparatus, a ROM 86 that stores various programs including a control program in advance, a RAM 87 that temporarily stores various data, and various data.
  • An HDD (Hard Disk Drive) 88 that stores and holds, a display driver 92 that controls display of various types of information on the display 80, and an operation input detector 90 that detects an operation state of the operation panel 82 are provided. .
  • the console 30 transmits and receives various information such as irradiation conditions described later between the image processing device 23 and the radiation generation device 24 by wireless communication, and various types of image data and the like with the electronic cassette 20.
  • An I / F (for example, a wireless communication unit) 96 and an I / O 94 that transmit and receive information are provided.
  • the CPU 84, ROM 86, RAM 87, HDD 88, display driver 92, operation input detection unit 90, I / O 94, and wireless communication unit 96 are connected to each other via a bus 98 such as a system bus or a control bus. Therefore, the CPU 84 can access the ROM 86, the RAM 87, and the HDD 88, controls the display of various information on the display 80 via the display driver 92, and the radiation generator 24 via the wireless communication unit 96. Control of transmission and reception of various types of information with the electronic cassette 20 can be performed. Further, the CPU 84 can grasp the operation state of the user with respect to the operation panel 82 via the operation input detection unit 90.
  • the image processing device 23 includes an I / F (for example, a wireless communication unit) 100 that transmits and receives various types of information such as irradiation conditions to and from the console 30, and the electronic cassette 20 and the radiation generation device 24 based on the irradiation conditions. And an image processing control unit 102 for controlling. Further, the radiation generator 24 includes a radiation irradiation control unit 22 that controls radiation irradiation from the radiation irradiation source 22A.
  • I / F for example, a wireless communication unit
  • the radiation generator 24 includes a radiation irradiation control unit 22 that controls radiation irradiation from the radiation irradiation source 22A.
  • the image processing control unit 102 includes a system control unit 104, a panel control unit 106, and an image processing control unit 108, and exchanges information with each other via a bus 110.
  • the panel control unit 106 receives information from the electronic cassette 20 wirelessly or by wire, and the image processing control unit 108 performs image processing.
  • the system control unit 104 receives information such as tube voltage and tube current as irradiation conditions from the console 30, and irradiates radiation X from the radiation irradiation source 22A of the radiation irradiation control unit 22 based on the received irradiation conditions. Take control.
  • the imaging system 16 has a function of automatically setting a region of interest based on the operation state of the captured image. , Control for setting a region of interest (hereinafter sometimes referred to as “ROI”) is executed.
  • ROI region of interest
  • appropriate image information is obtained by performing feedback correction of the radiation dose of the radiation to the subject by ABC “Auto Brightness Control” control.
  • FIG. 5 is a functional block diagram specialized in a control system for radiographic imaging (including ROI setting) in the imaging system 16 (mainly the electronic cassette 20, the console 30, the image processing device 23, and the radiation generation device 24). It is. Note that this block diagram categorizes radiographic imaging control by function and does not limit the hardware configuration.
  • the imaging system 16 includes a radiation dose irradiation control unit 22, a radiation dose adjustment unit 120, a TFT substrate 74, a signal acquisition unit 122, a structure detection unit 138, a region of interest extraction unit 140, and a still image generation unit. 128, the moving image editing unit 130, the display driver 92, the display 80, the average QL value calculation unit 132, the ABC control unit 134, and the reference QL value memory 136.
  • the radiation irradiation control unit 22 irradiates radiation from the radiation irradiation source 22A based on the radiation dose adjusted by the radiation dose adjustment unit 120.
  • the radiation irradiated to the subject from the radiation irradiation control unit 22 passes through the subject and reaches the radiation detector 26 (see FIG. 3) of the electronic cassette 20.
  • the radiation detector 26 the phosphor film 56 (see FIG. 3) emits light with a light amount corresponding to the radiation amount, and photoelectric conversion is performed by the TFT substrate 74 to generate a gradation signal.
  • the signal acquisition unit 122 acquires the gradation signal generated by the TFT substrate 74 and sends it to the still image generation unit 128.
  • the photoelectric conversion signal may be an analog signal or a signal after being converted into a digital signal by the control unit in the electronic cassette 20.
  • the still image generation unit 128 sequentially generates still images based on the gradation signal for one frame.
  • the photoelectric conversion signal itself sent from the electronic cassette 20 is different between the case of moving image shooting and the case of still image shooting.
  • the transfer speed is set to be different.
  • a binning process is performed to give priority.
  • image data based on the maximum number of pixels on the TFT substrate 74 is generated in order to prioritize image quality.
  • the moving image editing unit 130 performs moving image editing by combining the image data for each frame generated by the still image generating unit 128.
  • the edited moving image is displayed on the display 80 via the display driver 92.
  • the still image generated by the still image generating unit 128 is displayed on the display 80 via the display driver 92.
  • the structure detection unit 138 detects a target structure (a structure that is a candidate for a region of interest) based on each frame of the moving image generated by the moving image editing unit 130. For example, an assumed structure is detected from a menu or the like operated by the user using a process such as a histogram or a spatial filter.
  • the region-of-interest extraction unit 140 extracts a structure having a large change from the structures detected by the structure detection unit 138 as a region of interest, and sends the extraction result to the moving image editing unit 130. Thereby, the moving image editing unit 130 performs processing for making it possible to determine the region of interest.
  • the average QL value calculation unit 132 calculates the average value of the QL values of each frame (or one frame appropriately extracted) of the moving image.
  • the calculation result of the average value QL value calculation unit 132 is sent to the ABC control unit 134.
  • the QL value is a value corresponding to the density of the film of the radiographic image obtained by irradiating the radiation, and may be the gradation signal itself, or a predetermined process is performed on the gradation signal. It may be a signal.
  • the ABC control unit 134 compares the QL average value calculated by the average QL value calculation unit 132 with the reference QL value stored in the reference QL value memory 136 and converges the QL average value to the reference QL value.
  • Correction information ⁇ X is generated. This correction information ⁇ X is applied as a correction coefficient for increasing or decreasing the radiation dose (radiation energy) emitted from the radiation irradiation source 22A.
  • the correction information ⁇ X generated by the ABC control unit 134 is sent to the radiation dose adjustment unit 120.
  • the radiation dose adjustment unit 120 increases or decreases the radiation dose XN based on the correction information ⁇ X (XN ⁇ XN ⁇ ⁇ X).
  • the radiation dose adjusting unit 120 starts irradiation from a predetermined initial value at the time when the irradiation instruction is given, and then increases or decreases the radiation dose based on the correction information ⁇ X, and performs predetermined conditions (for example, constant (Period or condition change) so that the reference QL value is obtained.
  • the correction information ⁇ X is used as a multiplication (division) coefficient when correcting the radiation dose XN.
  • an addition (subtraction) coefficient (XN ⁇ XN + ⁇ XN) may be used.
  • the description will be made assuming that the radiation amount is corrected by the ABC control unit 134 so that the average value of the QL values of one frame becomes the reference QL value.
  • the ABC control unit 134 has at least one frame.
  • the radiation dose may be corrected so that the calculated value of the gradation signal in a part of the still image information falls within a predetermined range.
  • the ABC control unit 134 has the highest occurrence frequency when the occurrence frequency of the gradation signal of one frame is a histogram (for example, a histogram in which the horizontal axis is the gradation signal and the vertical axis is the occurrence frequency).
  • the radiation dose may be corrected so that the gradation (or a predetermined range of gradations including the maximum gradation) falls within a predetermined range of values.
  • FIG. 6 is a functional block unit showing detailed functions of the structure detection unit 138 and the region of interest extraction unit 140 according to the embodiment of the present invention.
  • the structure detection unit 138 includes a frame memory 142, a 1/2 reduced blurred image generation unit 144, a 1/4 reduced blurred image generation unit 146, a 2 ⁇ re-enlargement unit 148, and a 4 ⁇ re-enlargement unit. 150 and the function of the synthesis unit 152.
  • the frame memory 142 sequentially stores each frame of the moving image generated by the moving image editing unit 130 and sends it to the 1/2 reduced blurred image generating unit 144 frame by frame.
  • the 1/2 reduced blurred image generation unit 144 reduces the image of each frame to 1/2 and sends it to the 1/4 reduced blurred image generation unit 146 and the 2 ⁇ re-enlargement unit 148.
  • the 1/4 reduced blurred image generation unit 146 further reduces the image reduced to 1/2 to 1/2, thereby generating a 1/4 reduced image with respect to the original image and re-enlargement 4 times. To the unit 150.
  • the double re-enlargement unit 148 enlarges the image that has been reduced to 1 ⁇ 2 to double the original size and sends the image to the synthesis unit 152 again. That is, pixel information is thinned out by reducing the original image to 1 ⁇ 2. Then, by enlarging again, an image blurred with respect to the original image is generated.
  • the 4 ⁇ re-enlargement unit 150 enlarges the image reduced to 1 ⁇ 4 to 4 times and sends the image to the synthesis unit 152 in order to restore the original size. As a result, an image that is more blurred than the image generated by the double re-enlargement unit 148 is generated.
  • the synthesizing unit 152 synthesizes the images generated by the original image, the 2-times re-enlargement unit 148, and the 4-times re-enlargement unit 150, detects a structure that is a region of interest candidate, and extracts a region of interest. The result is sent to the unit 140.
  • the structure that is the target of the region of interest such as an organ is an image having a certain amount of mass. Therefore, the structure that is a candidate for the region of interest is detected by detecting the mass.
  • region-of-interest extraction unit 140 includes functions of an inter-frame difference processing unit 154 and a region-of-interest specifying unit 156 as shown in FIG.
  • the inter-frame difference processing unit 154 identifies a moving structure by calculating a difference between frames. More specifically, the change amount of the structure is obtained by obtaining the difference between frames for the structure detected by the structure detection unit 138.
  • the region-of-interest specifying unit 156 compares the amount of change of the structure calculated by the inter-frame difference processing unit 154, and specifies a structure having a change amount greater than or equal to a predetermined value as the region of interest.
  • a structure that is a region of interest such as a heart or a catheter in a blood vessel
  • the difference between the structures between the frames is calculated and the time difference is calculated.
  • a candidate for a structure having a fluctuation of a predetermined value or more is specified as a region of interest.
  • a structure having a new fluctuation amount of a predetermined value or more When an object candidate is detected, each structure is set as a plurality of regions of interest.
  • the region of interest specifying unit 156 extracts a non-interest region other than the specified region of interest, performs compression processing (irreversible compression) at a predetermined compression rate, and sets the region of interest as non-compressed to a moving image editing unit. Forward to 130.
  • the slew rate of data transfer is improved by performing data transfer by setting the compression rate of the non-region of interest to a compression rate higher than a predetermined compression rate. It has become.
  • the structure is detected by generating a blurred image by reducing and then re-enlarging the image, but a Gaussian pyramid forming unit used as a filtering process for generating a blurred image and
  • the structure may be detected by using at least one filter processing of the Laplacian pyramid forming unit, or the structure may be detected by using a directional filter used for detecting a camera shake direction of a digital camera. .
  • FIG. 7 is a flowchart showing a radiographic imaging preparation control routine.
  • step 200 it is determined whether or not a shooting instruction has been issued. If the determination is negative, the routine ends. If the determination is affirmative, the routine proceeds to step 202.
  • step 202 an initial information input screen is displayed on the display 80, and the process proceeds to step 204. That is, the display driver 92 is controlled to display a predetermined initial information input screen on the display 80.
  • step 204 it is determined whether or not predetermined information has been input.
  • the process waits until the determination is affirmed, and the process proceeds to step 206.
  • On the initial information input screen for example, the name of the subject who is going to take a radiographic image, the part to be imaged, the posture at the time of imaging, and the irradiation condition of the radiation X at the time of imaging (in this embodiment, the radiation X is irradiated)
  • a message prompting the user to input a tube voltage and a tube current), and an input area for the information.
  • the photographer When the initial information input screen is displayed on the display 80, the photographer displays the name of the subject to be imaged, the region to be imaged, the posture at the time of imaging, and the irradiation conditions in the corresponding input areas on the operation panel 82. Enter through.
  • the radiographer enters the radiography room 32 together with the subject.
  • the radio cassette 22A is handled by holding the electronic cassette 20 in the holding unit 44 of the corresponding prone position table 36. After positioning at the position, the subject is positioned (positioned) at a predetermined imaging position.
  • the subject and the electronic cassette 20 are ready to capture the imaging target site.
  • the radiation source 22A are positioned (positioned).
  • step 204 is affirmed and the routine proceeds to step 206.
  • step 204 is an infinite loop, but it may be forcibly terminated by operating a cancel button provided on the operation panel 82.
  • step 206 information input on the initial information input screen (hereinafter referred to as “initial information”) is transmitted to the electronic cassette 20 via the wireless communication unit 96, and then the process proceeds to the next step 208.
  • the irradiation conditions included in the initial information are set by transmitting the irradiation conditions to the radiation generator 24 via the wireless communication unit 96.
  • the image processing control unit 102 of the radiation generator 24 prepares for irradiation under the received irradiation conditions.
  • step 210 the start of ABC control is instructed, and then the process proceeds to step 212, where the instruction information instructing the start of radiation irradiation is transmitted to the radiation generator 24 via the wireless communication unit 96. Ends.
  • FIG. 8 is a flowchart showing a radiation irradiation control routine.
  • step 300 it is determined whether or not there has been an irradiation start instruction. If a negative determination is made, this routine ends. If an affirmative determination is made, the routine proceeds to step 302.
  • step 302 the radiation dose (initial value) XN at the time of steady state is read, and the process proceeds to step 304.
  • step 304 irradiation is started with the read steady-state radiation dose, and the process proceeds to step 306. That is, irradiation from the radiation irradiation source 22 ⁇ / b> A is started by applying a tube voltage and a tube current corresponding to the irradiation upper limit received from the console 30 to the radiation generator 24. The radiation X emitted from the radiation source 22A passes through the subject and reaches the electronic cassette 20.
  • step 306 currently stored radiation dose correction information is read, and the process proceeds to step 306.
  • This radiation dose correction information is generated by ABC control and is stored as a correction coefficient ⁇ X.
  • step 308 correction processing based on ABC control is executed, and the process proceeds to step 310. That is, based on the gradation signal (QL value) obtained from the electronic cassette 20, an average value of the QL values of the region of interest image is calculated, and the average value of the QL values is compared with a predetermined threshold value. The radiation dose is feedback controlled so as to converge to the threshold value.
  • QL value the gradation signal
  • step 310 it is determined whether or not an instruction to end shooting is given. If the determination is affirmative, the process proceeds to step 312. If the determination is negative, the process returns to step 306 and the above-described processing is repeated.
  • step 312 the irradiation is terminated, and the radiographic image capturing control is terminated.
  • FIG. 9 is a flowchart showing an image processing control routine.
  • step 400 gradation information for one frame is sequentially captured, and the process proceeds to step 402.
  • the gradation signal generated by the TFT substrate 74 of the electronic cassette 20 is sequentially taken in by the signal acquisition unit 122.
  • step 402 a still image is generated, and the process proceeds to step 404. That is, a still image is generated by the still image generation unit 128 when a grayscale signal for one frame is captured. Note that when a still image is generated, a still image that reflects a result adjusted by gradation adjustment control described later is generated.
  • step 404 the moving image editing process is performed, and the process proceeds to step 406.
  • moving image editing is performed by the moving image editing unit 130 by combining still images for each frame generated by the still image generating unit 128.
  • step 406 image display processing is performed, and the process proceeds to step 408.
  • the moving image generated by the moving image editing process is sent to the display driver 92, whereby the display driver 92 displays the moving image.
  • step 408 the region of interest is set, and the process proceeds to step 409.
  • the region of interest is set by structure detection and region-of-interest extraction processing described later.
  • step 409 it is determined whether or not a plurality of regions of interest are set. The determination determines whether or not a plurality of regions of interest have been specified in the structure detection and region-of-interest extraction processing described later, or whether or not a region of interest has been newly specified other than the specified region of interest, If the determination is negative, the process proceeds to step 410, and if the determination is affirmative, the process proceeds to step 411.
  • step 410 the gradation signal of the region of interest specified by the region of interest specifying unit 156 is extracted, and the process proceeds to step 412.
  • step 411 gradation signals of a plurality of regions of interest specified by the region of interest specifying unit 156 are extracted, and the process proceeds to step 412.
  • step 412 the average QL value of the gradation signal of the region of interest is calculated by the average QL value calculation unit 132, the process proceeds to step 414, the reference QL value stored in the reference QL value memory 136 is read, and step 416.
  • the average QL value of the gradation signals of the plurality of regions of interest is calculated, but the average QL value of the gradation signal of one of the regions of interest is calculated. May be calculated.
  • the average QL value of the grayscale signal of the region of interest detected first may be calculated, or the grayscale signal of the region of interest having a large amount of change calculated when specifying the region of interest.
  • the average QL value may be calculated. Or you may make it calculate the average QL value of the gradation signal of the region of interest emphasized according to predetermined weighting.
  • step 416 the calculated average QL value and the read reference QL value are compared by the ABC control unit 134 to determine whether correction is possible or not, and the process proceeds to step 418.
  • the determination as to whether or not correction is possible may be a so-called on / off determination in which a predetermined amount of correction is performed if the difference is greater than or equal to a predetermined value and no correction is performed if the difference is less than a predetermined value. Then, based on the difference, it may be a solution of a calculation by a predetermined calculation formula (for example, a calculation formula based on PID control or the like).
  • step 418 radiation amount correction information ⁇ X is generated by the ABC control unit 134 based on the comparison / correction propriety determination result in step 416, and the process proceeds to step 420.
  • step 420 the generated correction information ⁇ X is stored by being sent to the radiation dose adjustment unit 120, and the image processing control is terminated.
  • FIG. 10 is a flowchart showing a structure detection and region-of-interest extraction routine.
  • step 500 each frame of the moving image generated by the moving image editing unit 130 is sequentially stored in the frame memory 142, and the process proceeds to step 502.
  • step 502 a reduced blurred image is generated, and the process proceeds to step 504. That is, as shown in FIG. 11, the image of each frame is reduced to 1/2 by the 1/2 reduced blurred image generation unit 144, and the image of each frame is further reduced to 1/2 by the 1/4 reduced blurred image generation unit 146. The image is reduced to generate a quarter image.
  • step 504 a re-enlarged image is generated, and the process proceeds to step 506. That is, as shown in FIG. 11, the image reduced to 1 ⁇ 2 by the 2 ⁇ re-enlargement unit 148 is enlarged 2 times, and the image reduced to 1 ⁇ 4 by the 4 ⁇ re-enlargement unit 150 becomes 4 times. Enlarged.
  • step 506 the re-enlarged images are synthesized and the process proceeds to step 508. That is, as shown in FIG. 11, the original image, the image enlarged by the 2 ⁇ re-enlargement unit 148, and the image enlarged by the 4 ⁇ re-enlargement unit 150 are synthesized by the synthesis unit 152, and the process proceeds to step 508. .
  • step 508 the structure candidate is detected by the synthesis unit 152, and the process proceeds to step 510.
  • the target structure such as an organ becomes an image having a certain amount of mass
  • the image synthesized in step 506 becomes a blurred image. Therefore, as shown in FIG.
  • a structure candidate can be easily detected by detecting a block having a concentration of a predetermined area or more as a structure.
  • step 510 the inter-frame difference processing unit 154 calculates the inter-frame difference, and the process proceeds to step 512.
  • the difference between frames as shown in FIG. 12, the difference between frames is obtained for the structure detected by the structure detection unit 138.
  • the amount of change in the structure can be obtained by obtaining the difference in size between the structure candidates.
  • the region of interest extraction unit 140 determines whether or not there are a plurality of candidate structures. The determination is based on whether there are a plurality of structure candidates having a variation amount greater than or equal to a predetermined value among the structure candidates detected in step 510, or a new value greater than or equal to a predetermined value other than the region of interest that has already been set. It is determined whether or not a structure candidate having a variation amount has been found. If the determination is negative, the process proceeds to step 514, and if the determination is positive, the process proceeds to step 518.
  • step 514 a structure candidate having a fluctuation amount equal to or greater than a predetermined value is specified as a region of interest by the region of interest specifying unit 156, and the process proceeds to step 516.
  • step 516 the non-region of interest other than the region of interest is compressed at a predetermined compression rate (low compression), the region of interest is uncompressed, and the process proceeds to step 522. That is, a non-interest region other than the region of interest specified by the region-of-interest specifying unit 156 is extracted, and the data of the non-region of interest region is compressed at a predetermined compression rate and transferred to the moving image editing unit 130. Then, the region of interest is transferred to the moving image editing unit 130 as it is.
  • a predetermined compression rate low compression
  • step 518 the plurality of detected structure candidates are specified as the region of interest by the region of interest specifying unit 156, and the process proceeds to step 520.
  • step 520 the non-region of interest is compressed at a compression rate (high compression) higher than a predetermined compression rate, the region of interest is uncompressed, and the process proceeds to step 522. That is, a non-region of interest other than the region of interest specified by the region-of-interest specifying unit 156 is extracted, and a compression rate higher than a predetermined compression rate for the data of the non-region of interest region (compression when there is a single region of interest). The compression process is performed at a higher compression ratio) and transferred to the moving image editing unit 130, and the region of interest is transferred to the moving image editing unit 130 as it is.
  • ROI display processing is performed, and the structure detection and region of interest extraction processing ends.
  • the moving image editing unit 130 performs processing for making it possible to determine the specified region of interest by sending each frame of the moving image in which the region of interest is specified to the moving image editing unit 130. Is done. Then, each frame is sent to the display driver 90 to display a moving image on the display 80.
  • the region of interest can be identified by performing processing such as blinking of the region of interest, and the identified region of interest is displayed as a moving image.
  • a target structure is detected, a difference between frames is calculated for the detected structure, and a structure having a difference greater than or equal to a predetermined value is specified as a region of interest. ing. This makes it possible to identify a region of interest in motion, so that a heart or a catheter in a blood vessel can be easily set as the region of interest.
  • a plurality of regions of interest can be set in order to set these as regions of interest.
  • the non-region of interest is compressed and the region of interest is compressed, thereby improving the data transfer slew rate. Further, when a plurality of regions of interest are specified, the compression rate of the non-region of interest is further increased, so that the slew rate can be prevented from decreasing.
  • the radiation dose is corrected so that the average QL value of the gradation signal in the plurality of regions of interest becomes the reference QL value.
  • a plurality of regions of interest are weighted, and the radiation dose is corrected so that the average QL value of the gradation signal in the region of interest in which weight is important is the reference QL value.
  • FIG. 13 is a flowchart showing a modification of the image processing control routine. The same processes as those in the above embodiment are described with the same reference numerals.
  • step 400 gradation information for one frame is sequentially taken, and the process proceeds to step 402.
  • the gradation signal generated by the TFT substrate 74 of the electronic cassette 20 is sequentially taken in by the signal acquisition unit 122.
  • step 402 a still image is generated, and the process proceeds to step 404. That is, a still image is generated by the still image generation unit 128 when a grayscale signal for one frame is captured. Note that when a still image is generated, a still image that reflects a result adjusted by gradation adjustment control described later is generated.
  • step 404 the moving image editing process is performed, and the process proceeds to step 406.
  • moving image editing is performed by the moving image editing unit 130 by combining still images for each frame generated by the still image generating unit 128.
  • step 406 image display processing is performed, and the process proceeds to step 408.
  • the moving image generated by the moving image editing process is sent to the display driver 92, whereby the display driver 92 displays the moving image.
  • step 408 the region of interest is set, and the process proceeds to step 409.
  • the region of interest is set by structure detection and region-of-interest extraction processing described later.
  • step 409 it is determined whether or not a plurality of regions of interest are set. The determination determines whether or not a plurality of regions of interest have been specified in the structure detection and region-of-interest extraction processing described later. If the determination is negative, the process proceeds to step 410. If the determination is positive, The process proceeds to step 411.
  • step 410 the gradation signal of the region of interest specified by the region of interest specifying unit 156 is extracted, and the process proceeds to step 412.
  • step 411 the tone signal of the region of interest that places importance on the weight among the plurality of regions of interest specified by the region of interest specifying unit 156 is extracted, and the process proceeds to step 412.
  • the region of interest that places importance on the weight may, for example, focus on the region of interest specified first, or may focus on the newly specified region of interest later. Or you may make it attach importance to the region of interest with a large variation
  • step 412 the average QL value of the gradation signal of the region of interest is calculated by the average QL value calculation unit 132, the process proceeds to step 414, the reference QL value stored in the reference QL value memory 136 is read, and step 416.
  • step 416 the calculated average QL value and the read reference QL value are compared by the ABC control unit 134 to determine whether correction is possible or not, and the process proceeds to step 418.
  • the determination as to whether or not correction is possible may be a so-called on / off determination in which a predetermined amount of correction is performed if the difference is greater than or equal to a predetermined value and no correction is performed if the difference is less than a predetermined value. Then, based on the difference, a solution calculated by a predetermined arithmetic expression (for example, an arithmetic expression based on PID control or the like) may be used.
  • a predetermined arithmetic expression for example, an arithmetic expression based on PID control or the like
  • step 418 radiation amount correction information ⁇ X is generated by the ABC control unit 134 based on the comparison / correction propriety determination result in step 416, and the process proceeds to step 420.
  • step 420 the generated correction information ⁇ X is stored by being sent to the radiation dose adjustment unit 120, and the image processing control is terminated.
  • FIG. 14 is a flowchart showing a modification of the structure detection and region of interest extraction routine. The same processes as those in the above embodiment are described with the same reference numerals.
  • step 500 each frame of the moving image generated by the moving image editing unit 130 is sequentially stored in the frame memory 142, and the process proceeds to step 502.
  • step 502 a reduced blurred image is generated, and the process proceeds to step 504. That is, as shown in FIG. 11, the image of each frame is reduced to 1/2 by the 1/2 reduced blurred image generation unit 144, and the image of each frame is further reduced to 1/2 by the 1/4 reduced blurred image generation unit 146. The image is reduced to generate a quarter image.
  • step 504 a re-enlarged image is generated, and the process proceeds to step 506. That is, as shown in FIG. 11, the image reduced to 1 ⁇ 2 by the 2 ⁇ re-enlargement unit 148 is enlarged 2 times, and the image reduced to 1 ⁇ 4 by the 4 ⁇ re-enlargement unit 150 becomes 4 times. Enlarged.
  • step 506 the re-enlarged image is synthesized and the process proceeds to step 508. That is, as shown in FIG. 11, the original image, the image enlarged by the 2 ⁇ re-enlargement unit 148, and the image enlarged by the 4 ⁇ re-enlargement unit 150 are synthesized by the synthesis unit 152, and the process proceeds to step 508. .
  • step 508 the structure candidate is detected by the synthesis unit 152, and the process proceeds to step 510.
  • the target structure such as an organ becomes an image having a certain amount of mass
  • the image synthesized in step 506 becomes a blurred image. Therefore, as shown in FIG.
  • a structure candidate can be easily detected by detecting a block having a concentration of a predetermined area or more as a structure.
  • step 510 the inter-frame difference processing unit 154 calculates the inter-frame difference, and the process proceeds to step 512.
  • the difference between frames as shown in FIG. 12, the difference between frames is obtained for the structure detected by the structure detection unit 138.
  • the amount of change in the structure can be obtained by obtaining the difference in size between the structure candidates.
  • the region of interest extraction unit 140 determines whether or not there are a plurality of candidate structures. The determination is based on whether there are a plurality of structure candidates having a variation amount greater than or equal to a predetermined value among the structure candidates detected in step 510, or a new value greater than or equal to a predetermined value other than the region of interest that has already been set. It is determined whether or not a structure candidate having a variation amount has been found. If the determination is negative, the process proceeds to step 514, and if the determination is positive, the process proceeds to step 518.
  • step 514 a structure candidate having a variation amount equal to or greater than a predetermined value is specified as a region of interest by the region of interest specifying unit 156, and the process proceeds to step 516.
  • step 516 the non-region of interest other than the region of interest is compressed at a predetermined compression rate (low compression), the region of interest is uncompressed, and the process proceeds to step 522. That is, a non-interest region other than the region of interest specified by the region-of-interest specifying unit 156 is extracted, and the data of the non-region of interest region is compressed at a predetermined compression rate and transferred to the moving image editing unit 130. Then, the region of interest is transferred to the moving image editing unit 130 as it is.
  • a predetermined compression rate low compression
  • step 518 the plurality of detected structure candidates are specified as the region of interest by the region of interest specifying unit 156, and the process proceeds to step 519.
  • the non-region of interest is compressed with a compression rate (high compression) higher than a predetermined compression rate (low compression), and the region of interest is compressed with a predetermined compression rate for each weight.
  • the process proceeds to 522. That is, a non-interest region other than the region of interest specified by the region-of-interest specifying unit 156 is extracted, and the data of the non-interest region is compressed at a compression rate higher than a predetermined compression rate to obtain a moving image.
  • the region of interest is transferred to the editing unit 130, and the region of interest is compressed and transferred to the moving image editing unit 130 according to a predetermined weight. For example, weighting is performed in descending order of the amount of variation (difference value between frames) used to identify the region of interest, and compression processing is performed by increasing the compression rate as the weighting decreases.
  • the area may be uncompressed.
  • ROI display processing is performed, and the structure detection and region of interest extraction processing ends.
  • the moving image editing unit 130 performs processing for making it possible to determine the specified region of interest by sending each frame of the moving image in which the region of interest is specified to the moving image editing unit 130. Is done. Then, each frame is sent to the display driver 90 to display a moving image on the display 80.
  • the region of interest can be identified by performing processing such as blinking the region of interest or the region including the region of interest, and the identified region of interest is displayed as a moving image.
  • weighting when a plurality of regions of interest are specified and ABC control is performed, weighting is performed, and ABC control is performed on the region of interest that places importance on the weights, thereby performing a plurality of regions of interest. It is possible to prevent the entire region from being difficult to interpret.
  • weighting emphasizes the region of interest identified first, identifies the region of interest identified later, and places importance on the region of interest in which a candidate for a structure having a large amount of change is detected.
  • the present invention is not limited to this, and when a region of interest is specified, a weight may be input to the user.
  • the compression rate of the region of interest is changed according to the weighting, so that the slew rate when a plurality of regions of interest are set can be improved as compared to the above embodiment. .
  • the slew rate of data transfer is improved by compressing the non-interest area and transferring the data.
  • the method of improving the slew rate is not limited to this. Absent. For example, as shown in the flowchart of FIG. 15, when a plurality of regions of interest are set, the slew rate may be improved by changing the frame rate.
  • step 512 when it is determined in step 512 that there are a plurality of structure candidates and a plurality of structures are specified as the region of interest in step 514, the process proceeds to step 517, and the frame rate is changed (frame rate is lowered). The process may then proceed to step 522 to perform ROI display processing. For example, when there are a plurality of regions of interest, it is possible to suppress a decrease in the slew rate by displaying the frame rate at half or by lowering the frame rate as the number of regions of interest increases. . In addition to the compression process, the frame rate may be changed.
  • the frame rate is changed by changing the frame rate in step 517 in order to improve the slew rate when a plurality of regions of interest are specified.
  • the frame rate may be changed so as to increase the frame rate. That is, when a plurality of regions of interest are set, the lesion site (region of interest) can be observed in detail by increasing the frame rate.
  • the present invention is not limited to this.
  • other radiation such as ⁇ -rays and ⁇ -rays included.

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  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Human Computer Interaction (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

La présente invention concerne un dispositif de traitement d'image radiographique en mouvement, qui comprend : une unité de génération d'informations d'image qui génère des informations d'image fixe pour un cadre sur la base d'un signal de tonalité qui est généré en réponse à la quantité de rayonnement reçue par chaque pixel, et combine de multiples informations d'image fixe pour de multiples cadres en continu pour générer des informations d'image en mouvement ; une unité de détection qui détecte une structure d'intérêt sur la base des informations d'image fixe pour chaque cadre dans les informations d'image en mouvement, et une unité de définition de région d'intérêt qui calcule la différence entre les cadres relativement à la structure, définit la structure pour laquelle la différence calculée est supérieure ou égale à une valeur prédéterminée comme une région d'intérêt, et lorsqu'il y a multiples structures ayant chacune une valeur supérieure ou égale à la valeur prédéterminée ou lorsqu'une structure ayant une valeur supérieure ou égale à la valeur prédéterminée est nouvellement détectée pendant la définition de la région d'intérêt, définit les multiples structures ayant chacune une valeur supérieure ou égale aux valeurs prédéterminée comme régions d'intérêt.
PCT/JP2012/065788 2011-09-21 2012-06-20 Dispositif de traitement d'image radiographique en mouvement, dispositif de prise d'image radiographique en mouvement, système de prise d'image radiographique en mouvement, procédé de prise d'image radiographique en mouvement, et programme de prise d'image radiographique en mouvement WO2013042413A1 (fr)

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JP2011-206240 2011-09-21
JP2011206240 2011-09-21

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WO2013042413A1 true WO2013042413A1 (fr) 2013-03-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019047461A (ja) * 2017-09-07 2019-03-22 富士通株式会社 画像処理プログラム、画像処理方法および画像処理装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008125610A (ja) * 2006-11-17 2008-06-05 Shimadzu Corp Ｘ線透視撮影装置
WO2011074471A1 (fr) * 2009-12-18 2011-06-23 株式会社 日立メディコ Dispositif de diagnostic par image à rayons x, procédé de commande d'exposition aux rayons x et programme associé

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008125610A (ja) * 2006-11-17 2008-06-05 Shimadzu Corp Ｘ線透視撮影装置
WO2011074471A1 (fr) * 2009-12-18 2011-06-23 株式会社 日立メディコ Dispositif de diagnostic par image à rayons x, procédé de commande d'exposition aux rayons x et programme associé

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019047461A (ja) * 2017-09-07 2019-03-22 富士通株式会社 画像処理プログラム、画像処理方法および画像処理装置

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