WO2013024534A1 - 皮膚線量評価支援装置及び治療計画装置 - Google Patents
皮膚線量評価支援装置及び治療計画装置 Download PDFInfo
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Definitions
- the present invention relates to the creation of a treatment plan for a radiation therapy system, and more particularly to a skin dose evaluation support apparatus that can evaluate a skin dose and a surface area dose of an important organ.
- Such a treatment plan is generally implemented by software operating on a computer system.
- a three-dimensional region of a normal tissue to be noted and its surroundings are set using image data, and the coordinates are stored in a memory.
- the irradiation range (referred to as the irradiation field) determined according to the size of the lesion, the irradiation direction and the irradiation intensity determined temporarily, the three-dimensional dose distribution inside the human body using image data according to a certain physical model
- DVH Dose Volume Histogram
- DVH Dose Volume Histogram
- the irradiation direction and irradiation intensity are adopted for the treatment.
- the irradiation direction and irradiation intensity are determined again, and the dose distribution is changed again.
- the irradiation direction and the irradiation intensity adopted for the treatment are determined by repeating such operations.
- Patent Document 1 describes a three-dimensional image processing method for outputting a three-dimensional display in which a human tissue and a dose distribution obtained by calculation are superimposed in order to visually evaluate a treatment plan.
- the three-dimensional display where the calculated dose distribution is superimposed on the human tissue when the maximum dose value is 100% target dose, the dose distribution is displayed in the area above 10% target dose, or the dose distribution is 95% target
- the display is performed in such a manner that it is displayed in an area exceeding the dose, that is, the display condition of the dose distribution is changed.
- the lesion was included in an area of 10% or more of the target dose and slightly exceeded the area of 95% or more of the target dose, and the dose to the lesion was evaluated.
- the conventional three-dimensional image processing method can visually evaluate the dose to the lesion, it cannot visually evaluate the skin dose that is the dose to the skin.
- the present invention has been made to solve the above-described problems, and an object of the present invention is to obtain a skin dose evaluation support device that can accurately and intuitively grasp a skin dose in the preparation of a treatment plan.
- a skin dose evaluation support device includes a skin region contour creation unit that creates skin region information including boundary coordinates of a skin region based on image data input during a radiation treatment treatment plan for a patient, and a treatment plan device. Based on the dose distribution data calculated by the dose distribution calculation unit and the skin region information, the skin dose in the skin region is extracted, and display calculation is performed to create display data for displaying the extracted skin dose in a predetermined display format. And equipped with.
- the skin dose evaluation support device calculates the skin dose in the skin region based on the dose distribution data calculated by the dose distribution calculation unit of the treatment planning device and the skin region information created by the skin region contour creation unit. Since the extracted skin dose is displayed in a predetermined display format, the skin dose can be accurately and intuitively grasped in the treatment plan creation.
- FIG. 1 It is a figure which shows the structure of the skin dose evaluation assistance apparatus and treatment planning apparatus by Embodiment 1 of this invention. It is a figure which shows the radiotherapy system provided with the skin dose evaluation assistance apparatus by Embodiment 1 of this invention. It is a figure which shows the computer system which comprises the treatment plan apparatus of FIG. It is a figure which shows the dose distribution of the skin dose in the designated cross section. It is the figure which represented dose distribution of the skin dose by the three-dimensional display. It is the figure which changed the viewing angle in the three-dimensional display of FIG. It is a figure which shows several DVH containing DVH of a skin area
- FIG. 1 is a diagram showing a configuration of a skin dose evaluation support apparatus and a treatment planning apparatus according to Embodiment 1 of the present invention.
- FIG. 2 is a diagram showing a radiotherapy system including the skin dose evaluation support apparatus according to Embodiment 1 of the present invention.
- FIG. 3 is a diagram showing a computer system constituting the treatment planning apparatus of FIG.
- the radiotherapy system will be described with reference to FIG.
- the radiotherapy system according to the present invention includes a CT apparatus 101, a treatment planning apparatus 102, and a treatment apparatus 104.
- the treatment device 104 includes an accelerator 106, a gantry 107, an irradiation nozzle 108, a treatment bed 109, and a control device 105 that controls them.
- the CT apparatus 101 acquires a tomographic image of the human body to be treated.
- the human tomogram acquired by the CT apparatus 101 is input to the treatment planning apparatus 102.
- the treatment planning apparatus 102 calculates a dose distribution based on various parameters 103, and evaluates and determines the result. Then, these parameters 103 are changed several times to determine the most appropriate irradiation condition.
- the determined irradiation condition is input to the control device 105 in the treatment apparatus 104.
- the treatment planning device 102 includes a computer main body 201, an input device 202 for inputting data such as image data and an operator instruction, a display device 203 for displaying the results, the treatment planning software itself and output results. It is comprised from the memory
- the skin dose evaluation support apparatus is realized, for example, as software that operates in the treatment planning apparatus 102 or the like, and can be distributed via a portable recording medium such as a flexible disk or a CD-ROM, or a network.
- the skin dose evaluation support apparatus and treatment planning apparatus includes processing units such as a tissue region setting unit 302, a skin region outline creation unit 304, a dose distribution calculation unit 303, and a display calculation unit 305, and each processing unit receives an image via an input / output unit 301.
- Data 306, extraction data 307, parameters 103, irradiation conditions 310, display data 309, dose distribution data 311, and the like are input / output to / from the storage device 204 and the display device 203.
- the processing units of the input / output unit 301, the skin region outline creation unit 304, and the display calculation unit 305 constitute a skin dose evaluation support device 320.
- image data 306 captured by the CT apparatus 101 or the like is used.
- the image data here refers to data in which image density is stored in a three-dimensional array of voxels.
- image data 306 is input. Then, an extraction range or the like is designated by the parameter 103, an extraction result is obtained by the tissue region setting unit 302, and the result is stored in the storage device 204 as extraction data 307. For example, when performing tissue region setting, one lesion is set and a plurality of important tissues are set.
- the tissue region setting unit 302 obtains three-dimensional coordinates such as a body outline 401, a lesion 403, and important tissues 404 and 405 from image data 306 that is a three-dimensional image stored in a three-dimensional array of voxels. Is.
- the human body sectional view of FIG. 4 shows a body outline 401, a lesion 403, and important tissues 404 and 405.
- the tissue region setting unit 302 pays attention to, for example, a semi-automatic extraction method such as a method using an image density threshold or a region expansion method using tissue connection information, or each slice image output to a display device.
- the organization area is set by an area designation method in which the person traces the organization area.
- the skin region contour creation unit 304 automatically creates a skin region contour 402 that is a boundary of the skin region without the user being aware of it.
- the skin region contour creation unit 304 creates skin region information using a region surrounded by the body contour 401 and the skin region contour 402 as a skin region. Specifically, when the user operates the tissue region setting unit 302 to generate the body contour 401, the skin region contour 402, which is the contour on the inner side of the skin, is located on the inner side of the body contour 401 (a number more than the body contour). Automatically generated inside the pixel).
- the skin region information is the three-dimensional coordinates of the skin region, and includes at least the three-dimensional coordinates (boundary coordinates) of the skin region outline 402.
- the number of pixels from the body contour 401 and the skin region contour 402 to be generated inside can be changed by the parameter 103.
- it can be corrected by the user tracing the skin region contour 402 to be corrected in each slice image output to the display device 203 in the edit mode. It is. In this way, the thickness can be adjusted by the patient or by the body part by the edit mode.
- the dose distribution calculation unit 303 calculates a dose distribution by a dose distribution calculation method based on a physical model of each radiation.
- the dose distribution calculation of particle beams such as proton beam and carbon beam is calculated by, for example, the broad beam method, and the dose distribution calculation of X-ray is calculated by, for example, the TPR method.
- the dose distribution calculation unit 303 executes dose distribution calculation and outputs the dose distribution as voxel data stored in a three-dimensional array. When there are a plurality of irradiation directions, dose distribution calculation is performed for each of the plurality of irradiation directions, and a dose distribution in each irradiation direction is output.
- the irradiation condition 310 is input, and the process by the dose distribution calculation unit 303 is repeated each time, and the result is evaluated, whereby the final irradiation condition 310 and the dose distribution data 311 are evaluated.
- the display calculation unit 305 outputs the dose distribution state to the display device 203 as the display data 309 and displays the dose distribution state on the display device 203.
- the display calculation unit 305 creates display data such as a three-dimensional display, a cross-section isodose diagram display, a DVH display corresponding to a lesion, a target organ, a skin region, and the like.
- display calculation unit 305 displays the dose distribution data 311 calculated by the dose distribution calculation unit 303 and the skin region information created by the tissue region setting unit 302. Based on this, the skin dose in the skin region is extracted, and display data for displaying the extracted skin dose in a predetermined display format is created.
- the human tissue which is three-dimensional distribution data, and the dose distribution are three-dimensionally overlapped and displayed on the two-dimensional projection plane in a translucent manner as in the conventional case.
- a cross-section isodose diagram display for displaying the isodose diagram in the designated cross-section, a DVH display for displaying DVH, and the like are also displayed in the same manner as in the past.
- FIG. 5 is a diagram showing the dose distribution of the skin dose in a three-dimensional display.
- FIG. 5 shows an example of a bird's eye view of a body contour assembly 504, which is a human body displayed in a three-dimensional manner by laminating a plurality of body contours.
- the dose distribution which is three-dimensional distribution data
- the body outline aggregate 504 is an aggregate of outlines in a plurality of cross sections.
- the dose on the skin surface is displayed by isodose lines 505, 506, and 507.
- Each isodose line 505, 506, 507 is obtained by connecting the portions where the relative dose is the same numerical value when the maximum dose in all slice images of the image data 306 is normalized as 100%.
- the isodose line 505 is a line representing a relative dose in the skin area greater than 0%, for example, 0.1%
- the isodose line 506 is a line representing 60% relative dose in the skin area.
- Reference numeral 507 denotes a line representing a relative dose of 70% in the skin region.
- the dose index 501 is a dose index.
- the dose index 501 indicates a relative dose index.
- a region between the isodose line 505 and the isodose line 506 is a dose region that is larger than 0% and less than 60% of the relative dose, including data on the isodose line 505.
- a region between the isodose line 506 and the isodose line 507 is a dose region including 60% or more and less than 70% of the relative dose, including data on the isodose line 506.
- the region surrounded by the isodose line 507 is a dose region that is 70% or more and less than 80% of the relative dose, including the data on the isodose line 507.
- the display pattern indicating the relative dose region is omitted in order to prevent the drawing from being complicated.
- the positional relationship between the skin and the dose distribution of the skin can be intuitively grasped in the three-dimensional space by performing the three-dimensional display.
- the three-dimensional human body is represented by a body contour assembly 504, which is a collection of contours in a plurality of cross sections
- the skin and dose distribution display is not mixed with the display of other human body tissues. Can be clearly grasped.
- a region divided by numerical values such as a region where the relative dose is A% or more and less than B%, it is possible to quantitatively evaluate the influence of the skin dose.
- the pointer 502 it is also possible to display the dose 503 at that point.
- the display point When the display point is designated by the pointer 502, the numerical value of the skin dose corresponding to the display point is displayed. Display on the device 203. Thus, the dose at each point can be directly grasped.
- the dose index 501 can be displayed as an absolute dose display (cGy). Moreover, you may use the dose in an isocenter as a reference
- FIG. 6 is a diagram in which the viewing angle in the three-dimensional display of FIG. 5 is changed.
- the user can freely change the viewing angle by a mouse operation or the like in the three-dimensional display.
- the user can confirm the dose distribution on the skin surface from a desired angle.
- FIG. 4 is a diagram showing a dose distribution of a skin dose in a specified cross section.
- the dose in the skin area is displayed with isodose lines 411, 412, and 413.
- Each isodose line 411, 412, and 413 is connected with a line where the relative dose is the same value when the maximum dose in all slice planes of the image data 306 is normalized as 100% as in the description of FIG. It is a thing.
- the isodose line 411 is a line representing a relative dose in the skin area greater than 0%, for example, 0.1%
- the isodose line 412 is a line representing 60% relative dose in the skin area.
- Reference numeral 413 denotes a line representing a relative dose of 70% in the skin region.
- the dose index 406 is a dose index.
- the dose index 406 indicates a relative dose index.
- the region between the isodose line 411 and the isodose line 412 is a dose region that is greater than 0% and less than 60% of the relative dose, including the data on the isodose line 411.
- the area between the isodose line 412 and the isodose line 413 is a dose area that is 60% or more and less than 70% of the relative dose, including the data on the isodose line 412, and corresponds to the dose area 408 in FIG. .
- the region surrounded by the isodose line 413 is a dose range of 70% or more and less than 80% of the relative dose, including the data on the isodose line 413, and corresponds to the dose range 409 in FIG.
- the positional relationship between the skin and the dose distribution of the skin can be intuitively grasped.
- a region divided by numerical values such as a region where the relative dose is A% or more and less than B%, it is possible to quantitatively evaluate the influence of the skin dose.
- the dose index 501 can be displayed as an absolute dose display (cGy).
- the dose in an isocenter as a reference
- region of the relative dose was shown in the example which attached
- the DVH display will be described.
- the display calculation unit 305 performs a dose on the horizontal axis for the lesion, normal tissue set as shown in FIG. 7 or the entire human tissue of the image data 306 captured by the CT apparatus 101, Volume is plotted on the vertical axis, and the total sum of the entire tissue that is equal to or higher than the dose value is displayed on a graph for each dose value.
- FIG. 7 is a diagram showing a plurality of DVHs including DVHs in the skin region.
- the DVH characteristic line 602 is a characteristic for a lesion whose area is set, and is a line connecting the vertices of each VDH bar (not shown).
- the DVH characteristic line 604 is a characteristic for normal tissue
- the DVH characteristic line 605 is a characteristic for the whole human tissue.
- DVH characteristic lines 602, 604, and 605 are the same as in the prior art.
- the display calculation unit 305 can also display the DVH characteristic line 603 of the defined skin region.
- the horizontal and vertical scales of the graph can be changed independently.
- the horizontal axis can be displayed not only as an absolute dose but also as an isocenter or a relative dose (%) when the maximum dose is normalized as 100%.
- the DVH display it is possible to know how much volume is irradiated above the lethal dose in the lesion that is the treatment target and target tissue, and how much volume is suppressed below the tolerated dose in normal tissue. By looking at the DVH of the entire human tissue, it is possible to know how much the dose is dispersed throughout. In DVH of the whole human body tissue, it can be determined that a treatment plan that has as much volume as possible in a low dose range is a desirable treatment plan. In the DVH display, the dose distribution as a calculation result can be quantitatively evaluated. That is, a numerical value can be read by DVH display. As shown in FIG. 7, it is possible to obtain information on how much dose cGy is in what percentage of the total volume.
- the area where cGy or more enters the target tissue is what percentage or more of the total volume, the area where what cGy or more enters the important organ falls within what percentage or less of the total volume, etc. Because it has its own treatment protocol, it is important to quantify it as a DVH display.
- the skin dose evaluation support apparatus 320 can also display the DVH characteristic line 603 of the defined skin region by the display calculation unit 305 in the DVH display as described above. Since the skin dose evaluation support apparatus 320 can display the DVH characteristic line 603 of the skin region, it is possible to obtain information on how many cGy in the skin region fall within the total volume of the skin region, and the dose that is the calculation result Distribution can be quantitatively evaluated.
- the display calculation unit 305 can display a dose on the horizontal axis and an area (cm 2 ) on the vertical axis, and can display an area that is greater than or equal to the dose value irradiated in the skin region. Can be quantitatively evaluated.
- FIG. 8 is a diagram showing the relationship between the dose and the area of the skin region. The relationship between the dose and area of the skin region shown in FIG. 8 is referred to herein as DAH (Dose Area Histogram). 701 in FIG. 8 is a DAH characteristic line of the defined skin region.
- Conventional DVH is an index for viewing the relationship between the dose and volume irradiated to a target tissue or important organ.
- Quantification of how much cGy of the part irradiated with the skin dose on the surface of the skin is how many cm 2 , that is, how high the area is irradiated by making the vertical axis the area like DAH display that displays DAH Information can be obtained.
- it can be used as a material for determining how much area of skin irritation occurs after irradiation.
- the vertical axis of the DAH display can be an area (%) in addition to the area (cm 2 ).
- the vertical axis of DAH display is the area (%), it is possible to obtain information on how many cGy of skin dose falls in what percentage of the total area of the skin region.
- the horizontal axis can be displayed not only as an absolute dose but also as an isocenter or a relative dose (%) when normalized with the maximum dose as 100%.
- the cross-section isodose map display (FIG. 4), the DVH display (FIG. 7), and the DAH display (FIG. 8)
- the skin dose evaluation support apparatus 320 of the first embodiment displays a predetermined display format for visually displaying the skin dose, specifically, a three-dimensional display, a cross-section isodose diagram display, a DVH display, and a DAH display. Can be displayed.
- the treatment plan apparatus 102 provided with the skin dose evaluation support apparatus 320 can accurately and intuitively grasp the skin dose in creating the treatment plan by using these displays. Since the treatment planning apparatus 102 can accurately and intuitively grasp the skin dose, it is possible to create a treatment plan that can reduce skin inflammation as much as possible.
- the treatment planning apparatus 102 can appropriately change the conditions in the treatment plan and repeat the simulation by the evaluation based on various displays of the skin dose of the skin dose evaluation support apparatus 320, and obtain a desired result with a short number of simulations.
- Whether or not skin irritation occurs will vary somewhat depending on the fractional irradiation, the site, etc., but the standard is determined to some extent such that it will occur when cGy or more is exposed. Therefore, by creating a skin region and displaying a DVH display or a DAH display, it is possible to obtain information such as what percentage of the region or how many cm 2 of the region has a dose of cGy or more. By assessing skin dose during treatment planning, it is possible to accurately and intuitively understand how much skin is inflamed, and based on the results, to minimize skin irritation It can be reflected in the treatment plan.
- the skin dose evaluation support apparatus 320 automatically creates a skin region contour by the skin region contour creation unit 304. Therefore, it is troublesome for the image data 306 captured by the user with a hundred or more CTs. It is possible to omit the work of defining (setting) the inner contour inside the body contour 401 for each slice image of the image data 306. In addition, when the task of creating the inner contour that determines the skin area is performed manually, this task takes time, and it takes a very long time to create a treatment plan that reflects the evaluation result of the skin dose. Such a problem occurs.
- the skin dose evaluation support apparatus 320 according to the first embodiment includes the skin region contour creation unit 304.
- the inner contour for determining the skin region that is, the skin region contour 402 can be created in a short time, and the evaluation result of the skin dose is obtained.
- the treatment plan to be reflected can be completed in a short time.
- the skin region contour 402 can be created by the skin region contour creating unit 304 and can be adjusted by the edit mode, so that the accurate skin region contour 402 can be created in a short time.
- the skin region information including the boundary coordinates of the skin region based on the image data 306 input when the radiation therapy treatment plan for the patient is performed.
- the skin dose in the skin region is extracted and extracted.
- the display calculation unit 305 for creating display data 309 for displaying the skin dose in a predetermined display format is provided, so that the skin dose in the skin region extracted based on the dose distribution data 311 and the skin region information is predetermined.
- the tissue region setting unit 302 that acquires the three-dimensional coordinates of the body contour, the important organ, and the lesion to be treated, and the radiotherapy Based on a model corresponding to the radiation to be used, a dose distribution calculation unit 303 that calculates the dose distribution of the patient, and a skin dose evaluation support device 320 that displays the skin dose in the skin area of the patient on the display device 203, are provided.
- the evaluation support apparatus 320 creates a skin region contour creation unit 304 that creates skin region information including boundary coordinates of the skin region, dose distribution data 311 calculated by the dose distribution calculation unit 303, and skin region information.
- the skin dose in the skin region is extracted, and display data 309 for displaying the extracted skin dose in a predetermined display format is obtained. Since a display calculation unit 305 for forming, by skin dose evaluation support apparatus 320 can be accurately and intuitively grasp the skin dose, it is possible to create a treatment plan that inflammation of the skin can be reduced even a little.
- the treatment planning apparatus 102 can appropriately change the conditions in the treatment plan and repeat the simulation by the evaluation based on various displays of the skin dose of the skin dose evaluation support apparatus 320, and obtain a desired result with a short number of simulations.
- FIG. 9 is a diagram showing a configuration of a skin dose evaluation support apparatus according to Embodiment 2 of the present invention.
- the skin dose evaluation support apparatus 801 includes an input / output unit 805, a skin region outline creation unit 304, and a display calculation unit 305.
- the input / output unit 805 takes in the image data 306, contour data 802, plan data 803, and dose distribution data 311 from the treatment planning apparatus 102 in the DICOM data format via the input / output unit 805.
- the skin dose evaluation support apparatus 801 is configured by a computer system as shown in FIG.
- the treatment planning apparatus 102 according to the second embodiment corresponds to the treatment planning apparatus 102 according to the first embodiment in which the skin region contour creation unit 304 is deleted.
- the contour data 802 is tissue region data set by the tissue region setting unit 302 of the treatment planning apparatus 102.
- the plan data 803 is irradiation conditions simulated by the treatment planning apparatus 102, and the dose data 804 is dose data calculated by the treatment planning apparatus 102 performing simulation.
- the skin dose evaluation support apparatus 801 automatically generates the skin region contour 402 inside the body contour 401 (several pixels inside the body contour) by the skin region contour creating unit 304.
- the display calculation unit 305 performs display processing such as three-dimensional display, isodose diagram display, and DVH display, and skin region contour creation for a conventional labeled tissue, normal tissue, or an entire human tissue imaged by a CT apparatus.
- Display processing of the three-dimensional display, isodose diagram display, DVH display, and DAH display of the skin region created by the unit 304 is performed.
- the input / output unit 805 outputs the display data 309 processed and generated by the display calculation unit 305 to the display device 203 and the storage device 204.
- the skin dose evaluation support apparatus 801 of the second embodiment is independent of the treatment planning apparatus 102, it can be easily added without making a major change to the existing treatment planning apparatus. Therefore, the effects described in the first embodiment can be exhibited while using an existing treatment planning apparatus.
- the skin dose evaluation support apparatus 801 of the second embodiment can visually display the skin dose, and can accurately and intuitively grasp the skin dose in creating a treatment plan.
- Embodiment 3 The dose evaluation technique in the skin dose evaluation support apparatus 320 of the first embodiment and the skin dose evaluation support apparatus 801 of the second embodiment can be applied to designated important organs.
- Embodiment 3 is an example in which the dose evaluation technique for skin dose is applied to designated important organs.
- FIG. 10 is a diagram showing a configuration of a skin dose evaluation support apparatus according to Embodiment 3 of the present invention
- FIG. 11 is a diagram showing a configuration of another skin dose evaluation support apparatus according to Embodiment 3 of the present invention.
- a skin region outline creation unit 315 is added.
- the skin region contour creating unit 315 automatically creates a contour for evaluating an important organ surface dose, and has the same function as the skin region contour creating unit 304.
- the organ surface region contour creation unit 315 includes the tissue region (outer contour) set by the tissue region setting unit 302 and the contour information (inner contour) for critical organ surface dose evaluation created by the organ surface region contour creation unit 315.
- the surface area information of the organ surface area surrounded by is created.
- the surface area information corresponds to skin area information.
- the skin dose evaluation support devices 320 and 801 display the surface area dose on the display device 203 in the display format of three-dimensional display, cross-section isodose diagram display, DVH display, and DAH display for the surface area of the designated important organ. To do. Intestinal organs such as the stomach, small intestine, large intestine, and rectum increase the risk of causing gastric ulcers, gastrointestinal bleeding, etc.
- the dose evaluation technology of the skin dose evaluation support devices 320 and 801 to the important organ, the dose can be visually displayed on the surface area of the designated important organ, and the treatment plan is created. Can accurately and intuitively grasp the surface area dose. In addition, it is possible to create a treatment plan that can alleviate a disorder such as a gastric ulcer in the surface area of an important organ.
- the surface area of the organ of the patient based on the image data 306 input when the radiation therapy treatment plan for the patient is used.
- the organ surface region contour creating unit 315 that creates surface region information including boundary coordinates of the organ surface region
- the dose distribution data 311 calculated by the dose distribution calculating unit 303 of the treatment planning apparatus 102 Since it has a display calculation unit 305 that extracts organ surface dose in the organ surface region and generates display data for displaying the extracted organ surface dose in a predetermined display format, dose distribution data 311 and organ surface region information are provided.
- the organ surface dose is visually displayed by displaying the organ surface dose in the organ surface area extracted based on Rukoto can, the organ surface dose can be accurately and intuitively grasp in treatment planning.
- the tissue region setting unit 302 that acquires the three-dimensional coordinates of the body contour, the important organ, and the lesion to be treated, and the radiotherapy Based on a model corresponding to the radiation to be used, a dose distribution calculation unit 303 that calculates the dose distribution of the patient, and the skin that displays the skin dose in the skin area of the patient and the surface area dose in the surface area of the patient organ on the display device 203
- the skin dose evaluation support device 320 includes a skin region outline creation unit 304 that creates skin region information including the boundary coordinates of the skin region based on the image data 306, and a radiation treatment treatment for the patient.
- surface area information including boundary coordinates of the organ surface area, which is the surface area of the patient's organ.
- the skin dose in the skin region is extracted, and the dose distribution data 311 and the surface region A display calculation unit 305 that extracts organ surface doses in the organ surface area based on the information and creates display data for displaying the extracted skin dose and surface area dose in a predetermined display format.
- the skin dose evaluation support devices 320 and 801 can accurately and intuitively grasp the skin dose and the surface area dose, and create a treatment plan that can alleviate the skin inflammation and the gastric ulcer in the surface area of important organs as much as possible. be able to.
- the treatment planning apparatus 102 can appropriately change the conditions in the treatment plan and repeat the simulation by the evaluation based on various displays of the skin dose of the skin dose evaluation support apparatus 320, and obtain a desired result with a short number of simulations.
- the apparatus which applied the dose evaluation technique of the skin dose evaluation support apparatuses 320 and 801 with respect to an important organ may be called a surface area dose evaluation support apparatus.
- the skin dose evaluation support device 320 and the treatment planning device 102 of the first embodiment, the skin dose evaluation support device 801 of the second embodiment, the skin dose evaluation support devices 320 and 801 of the third embodiment, and the treatment planning device 102 are the same.
- the present invention can also be applied to radiotherapy systems using charged particles such as electron beams, comma beams, and the like.
- Organ surface region outline creation unit 320 ... Skin dose evaluation support device, 401 ... Body outline, 404 ... Important organ, 405 ... Important organ, 502 ... Pointer, 504... Body contour aggregate (human body image), 603... DVH characteristic line, 701. DAH characteristic line, 801.
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Abstract
Description
図1は、本発明の実施の形態1による皮膚線量評価支援装置及び治療計画装置の構成を示す図である。図2は、本発明の実施の形態1による皮膚線量評価支援装置を備えた放射線治療システムを示す図である。図3は、図2の治療計画装置を構成するコンピュータシステムを示す図である。図2を用いて、放射線治療システムについて説明する。本発明の放射線治療システムは、CT装置101と、治療計画装置102と、治療装置104とから構成されている。また、治療装置104は、加速器106と、ガントリー107と、照射ノズル108と、治療ベッド109とこれらを制御する制御装置105から構成されている。
実施の形態1では、治療計画装置102に皮膚線量評価支援装置320が備えられた例で説明した。実施の形態2では、皮膚線量評価支援装置を治療計画装置102から独立させた例を説明する。図9は、本発明の実施の形態2による皮膚線量評価支援装置の構成を示す図である。皮膚線量評価支援装置801は、入出力部805、皮膚領域輪郭作成部304、表示計算部305を有する。入出力部805は、治療計画装置102からDICOMデータ形式にて、画像データ306、輪郭データ802、計画データ803、線量分布データ311を、入出力部805を介して取り込む。皮膚線量評価支援装置801は、図2のようにコンピュータシステムで構成される。実施の形態2の治療計画装置102は、実施の形態1の治療計画装置102から皮膚領域輪郭作成部304を削除したものに相当する。
実施の形態1の皮膚線量評価支援装置320や実施の形態2の皮膚線量評価支援装置801における線量評価技術を、指定した重要臓器に対しても適用することができる。実施の形態3では、皮膚線量の線量評価技術を、指定した重要臓器に対しても適用する例である。図10は本発明の実施の形態3による皮膚線量評価支援装置の構成を示す図であり、図11は本発明の実施の形態3による他の皮膚線量評価支援装置の構成を示す図である。実施の形態3による皮膚線量評価支援装置は、皮膚領域輪郭作成部315が追加されている。皮膚領域輪郭作成部315は、重要臓器表面線量評価用の輪郭を自動的に作成するものであり、皮膚領域輪郭作成部304と同様な機能を有する。
303…線量分布計算部、304…皮膚領域輪郭作成部、305…表示計算部、306…画像データ、309…表示データ、311…線量分布データ、
315…臓器表面領域輪郭作成部、320…皮膚線量評価支援装置、401…体輪郭、404…重要臓器、405…重要臓器、502…ポインタ、
504…体輪郭集合体(人体画像)、603…DVH特性線、701…DAH特性線、801…皮膚線量評価支援装置。
Claims (16)
- 患者の皮膚領域における皮膚線量を表示装置に表示する皮膚線量評価支援装置であって、
前記患者に対する放射線治療の治療計画の際に入力される画像データに基づいて、前記皮膚領域の境界座標を含む皮膚領域情報を作成する皮膚領域輪郭作成部と、
治療計画装置の線量分布計算部により計算された線量分布データと前記皮膚領域情報とに基づいて、前記皮膚領域における前記皮膚線量を抽出し、この抽出された前記皮膚線量を所定の表示形式に表示する表示データを作成する表示計算部とを備えたことを特徴とする皮膚線量評価支援装置。 - 前記表示計算部は、前記皮膚線量の分布を3次元表示された人体画像に重ね合わせて表示する3次元表示する表示データを作成することを特徴とする請求項1記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記皮膚線量の分布を前記患者の指定された断面に重ね合わせて表示する表示データを作成することを特徴とする請求項1または2に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記表示装置に表示された前記皮膚線量の分布において、ポインタによって表示点が指定された場合に、前記表示点に対応した前記皮膚線量の数値を前記表示装置に表示することを特徴とする請求項2または3に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記皮膚領域における前記皮膚線量と当該皮膚線量の数値を示す組織体積との関係を表すグラフである第1のDVHを作成し、前記第1のDVHを前記表示装置に表示することを特徴とする請求項1乃至4のいずれか1項に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記皮膚領域における前記皮膚線量と当該皮膚線量の数値を示す面積との関係を表すグラフである第1のDAHを作成し、前記第1のDAHを前記表示装置に表示することを特徴とする請求項1乃至5のいずれか1項に記載の皮膚線量評価支援装置。
- 前記皮膚領域輪郭作成部は、前記画像データに設定された体輪郭の情報に基づいて前記皮膚領域情報を作成することを特徴とする請求項1乃至6のいずれか1項に記載の皮膚線量評価支援装置。
- 前記画像データに基づいて、前記患者の臓器の表面領域である臓器表面領域の境界座標を含む表面領域情報を作成する臓器表面領域輪郭作成部を備え、
前記表示計算部は、前記線量分布データと前記表面領域情報とに基づいて、前記臓器表面領域における表面領域線量を抽出し、この抽出された前記表面領域線量を所定の表示形式にて前記表示装置に表示する表示データを作成することを特徴とする請求項1乃至7のいずれか1項に記載の皮膚線量評価支援装置。 - 前記表示計算部は、前記表面領域線量の分布を3次元表示された人体画像に重ね合わせて表示する3次元表示する表示データを作成することを特徴とする請求項8記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記表面領域線量の分布を前記患者の指定された断面に重ね合わせて表示する表示データを作成することを特徴とする請求項8または9に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記表示装置に表示された前記表面領域線量の分布において、ポインタによって表示点が指定された場合に、前記表示点に対応した前記表面領域線量の数値を前記表示装置に表示することを特徴とする請求項9または10に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記臓器表面領域における前記表面領域線量と当該表面領域線量の数値を示す組織体積との関係を表すグラフである第2のDVHを作成し、前記第2のDVHを前記表示装置に表示することを特徴とする請求項8乃至11のいずれか1項に記載の皮膚線量評価支援装置。
- 前記表示計算部は、前記臓器表面領域における前記表面領域線量と当該表面領域線量の数値を示す面積との関係を表すグラフである第2のDAHを作成し、前記第2のDAHを前記表示装置に表示することを特徴とする請求項8乃至12のいずれか1項に記載の皮膚線量評価支援装置。
- 前記臓器表面領域輪郭作成部は、前記画像データに設定された外側輪郭の情報に基づいて前記表面領域情報を作成することを特徴とする請求項8乃至13のいずれか1項に記載の皮膚線量評価支援装置。
- 患者に対する放射線治療の治療計画を作成する治療計画装置であって、
前記患者の画像データに基づいて、体輪郭、重要臓器、治療対象である病巣の3次元座標を取得する組織領域設定部と、
前記放射線治療に用いる放射線に対応したモデルに基づいて、前記患者の線量分布を計算する線量分布計算部と、
前記患者の皮膚領域における皮膚線量を表示装置に表示する皮膚線量評価支援装置とを備え、
前記皮膚線量評価支援装置は、請求項1乃至7のいずれか1項に記載の皮膚線量評価支援装置であることを特徴とする治療計画装置。 - 患者に対する放射線治療の治療計画を作成する治療計画装置であって、
前記患者の画像データに基づいて、体輪郭、重要臓器、治療対象である病巣の3次元座標を取得する組織領域設定部と、
前記放射線治療に用いる放射線に対応したモデルに基づいて、前記患者の線量分布を計算する線量分布計算部と、
前記患者の皮膚領域における皮膚線量及び前記患者の臓器の表面領域における表面領域線量を表示装置に表示する皮膚線量評価支援装置とを備え、
前記皮膚線量評価支援装置は、請求項8乃至14のいずれか1項に記載の皮膚線量評価支援装置であることを特徴とする治療計画装置。
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- 2011-08-17 US US14/118,729 patent/US9314646B2/en not_active Expired - Fee Related
- 2011-08-17 EP EP11870949.2A patent/EP2745874A4/en not_active Withdrawn
- 2011-08-17 CN CN201180072463.3A patent/CN103702716B/zh not_active Expired - Fee Related
- 2011-08-17 WO PCT/JP2011/068604 patent/WO2013024534A1/ja active Application Filing
- 2011-08-17 JP JP2013528884A patent/JP5665994B2/ja not_active Expired - Fee Related
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Cited By (8)
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WO2014167461A1 (en) * | 2013-04-11 | 2014-10-16 | Koninklijke Philips N.V. | Isodose optimization |
US10124189B2 (en) | 2013-04-11 | 2018-11-13 | Koninklijke Philips N.V. | Isodose optimization |
CN104107062A (zh) * | 2013-04-17 | 2014-10-22 | 深圳市医诺智能科技发展有限公司 | 一种评估放射治疗效果方法及系统 |
CN104107062B (zh) * | 2013-04-17 | 2016-08-10 | 深圳市医诺智能科技发展有限公司 | 一种评估放射治疗效果方法及系统 |
WO2015146164A1 (ja) * | 2014-03-28 | 2015-10-01 | 独立行政法人放射線医学総合研究所 | 放射線照射による皮膚変化予測装置と検証装置 |
JPWO2015146164A1 (ja) * | 2014-03-28 | 2017-04-13 | 国立研究開発法人量子科学技術研究開発機構 | 放射線照射による皮膚変化予測装置と検証装置 |
US10315052B2 (en) | 2014-03-28 | 2019-06-11 | National Institutes For Quantum And Radiological Science And Technology | Prediction device for skin change from radiation exposure, and verification device |
JP2021045560A (ja) * | 2016-10-28 | 2021-03-25 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 反復的治療計画のためのグラフィックユーザインターフェース |
Also Published As
Publication number | Publication date |
---|---|
US20140094642A1 (en) | 2014-04-03 |
US9314646B2 (en) | 2016-04-19 |
CN103702716B (zh) | 2016-03-30 |
JPWO2013024534A1 (ja) | 2015-03-05 |
EP2745874A1 (en) | 2014-06-25 |
CN103702716A (zh) | 2014-04-02 |
JP5665994B2 (ja) | 2015-02-04 |
TWI469766B (zh) | 2015-01-21 |
TW201309267A (zh) | 2013-03-01 |
EP2745874A4 (en) | 2015-03-25 |
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