WO2012114781A1 - 塗布具 - Google Patents
塗布具 Download PDFInfo
- Publication number
- WO2012114781A1 WO2012114781A1 PCT/JP2012/050047 JP2012050047W WO2012114781A1 WO 2012114781 A1 WO2012114781 A1 WO 2012114781A1 JP 2012050047 W JP2012050047 W JP 2012050047W WO 2012114781 A1 WO2012114781 A1 WO 2012114781A1
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- WO
- WIPO (PCT)
- Prior art keywords
- nozzle
- applicator
- tip
- light
- irradiation unit
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
- A61B2017/003—Steerable
- A61B2017/00318—Steering mechanisms
- A61B2017/00331—Steering mechanisms with preformed bends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
- A61B2017/00495—Surgical glue applicators for two-component glue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00491—Surgical glue applicators
- A61B2017/00522—Sprayers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00535—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
- A61B2017/00544—Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated pneumatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/0084—Material properties low friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2901—Details of shaft
- A61B2017/2904—Details of shaft curved, but rigid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
- A61B2090/309—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using white LEDs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/02—Spray pistols; Apparatus for discharge
- B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
- B05B7/0408—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing two or more liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/24—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas with means, e.g. a container, for supplying liquid or other fluent material to a discharge device
- B05B7/2402—Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device
- B05B7/2405—Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device using an atomising fluid as carrying fluid for feeding, e.g. by suction or pressure, a carried liquid from the container to the nozzle
- B05B7/2424—Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising containers fixed to the discharge device using an atomising fluid as carrying fluid for feeding, e.g. by suction or pressure, a carried liquid from the container to the nozzle the carried liquid and the main stream of atomising fluid being brought together downstream of the container before discharge
Definitions
- This invention relates to the applicator which discharges a chemical
- an anti-adhesion material is used to prevent such adhesion.
- the sheet-like anti-adhesive material is attached under the incision, the tissue under the incision moves, so that the incision and the tissue cannot be reliably separated.
- the present invention has been made in view of such problems, and an object thereof is to provide an applicator that can reliably apply a drug to a target site.
- the present invention provides an applicator that discharges a drug and applies it to a target site, the applicator main body, a nozzle extending from the applicator main body, and a tip of the nozzle. And an irradiating unit that emits light that is directed and diffuses toward the tip of the nozzle.
- the diffused light is irradiated in the direction in which the nozzle is directed by the irradiation unit provided at the tip of the nozzle, the direction of the nozzle tip and the position of the light irradiation and the size of the portion are determined.
- the approximate distance to the irradiated site can be predicted. Therefore, the medicine can be reliably applied to the target site.
- the nozzle has a long nozzle body extending from the applicator main body and having a curved portion on the tip end side, and a nozzle head provided at the tip of the nozzle body,
- the said irradiation part is good to be arrange
- the irradiation part is located on the opposite side of the nozzle tip from the side where the medicine tends to sag, so that the medicine hardly adheres to the irradiation part. Therefore, light can be reliably irradiated in the direction in which the nozzle tip is directed by the irradiation unit. Moreover, the position where the nozzle tip is oriented can be easily adjusted to the incision or wound.
- the nozzle is configured to spray the medicine, and the diffusion diameter of the medicine ejected from the nozzle and the diffusion diameter of the light emitted from the irradiation section may be approximately the same.
- the spray range of the drug can be predicted based on the size of the light diffusion diameter. Therefore, the medicine can be easily applied to a desired range.
- the irradiation unit may include a light source, and a conductive member that guides a current from a power supply unit to the light source may be disposed along the nozzle.
- the nozzle is provided at the tip of the nozzle body, and a long nozzle body extending from the applicator body and having a flexible curved portion on the tip side.
- the applicator further includes a shape regulating member that is movably provided along the longitudinal direction of the nozzle body and that changes the shape of the curved portion according to the position in the longitudinal direction.
- the conductive member may be disposed through the inside of the shape regulating member.
- a configuration in which light is irradiated in the direction of the tip of the nozzle can be configured at low cost.
- the conductive member is covered with the shape regulating member, the conductive member can be easily and well wired along the nozzle.
- the irradiation unit may be configured by a lens that diffuses light, and a light guide member that guides light from a light source to the lens may be disposed along the nozzle.
- the nozzle includes a long nozzle body extending from the applicator main body and having a flexible curved portion on the tip side, and a nozzle head provided at the tip of the nozzle body.
- the applicator further includes a shape regulating member that is movably provided along the longitudinal direction of the nozzle body and that changes the shape of the curved portion according to the position in the longitudinal direction. It is good to arrange
- the tip of the nozzle can be made compact. Moreover, since the light guide member is covered with the shape regulating member, the light guide member can be easily wired along the nozzle.
- the drug can be reliably applied to the target site.
- FIG. 4A is a schematic view of the applicator in a state where the curved portion of the nozzle is curved
- FIG. 4B is a schematic view of the applicator in a state where the curved portion of the nozzle is regulated in a straight line.
- FIG. 4B is a schematic view of the applicator in a state where the curved portion of the nozzle is regulated in a straight line.
- FIG. 1 is a partially omitted perspective view of an applicator 10 according to an embodiment.
- the applicator 10 applies two kinds of liquids having different liquid compositions (hereinafter, for convenience of explanation, the two kinds of liquids are referred to as “first liquid” and “second liquid”, respectively) while mixing.
- the first syringe (supplying means) 12a and the second syringe (supplying means) 12b are connected in parallel and integrally connected to the syringe (applicator main body) 12, and each tip of the syringe 12 is connected.
- the spray device includes a nozzle 14 that ejects the first liquid and the second liquid filled in the syringe 12 onto the application target.
- the applicator 10 inserts the nozzle 14 into the abdominal cavity, for example, during laparoscopic surgery, and mixes the first and second liquids having different liquid compositions supplied from the syringe 12 within the nozzle 14 It is used as a medical device for applying a drug solution as a mixture to an organ, abdominal wall, or the like.
- the syringe 12 includes a first syringe 12a and a second syringe 12b corresponding to two kinds of liquids mixed and ejected by the nozzle 14, and fills the first syringe 12a with liquid and fills the second syringe 12b with liquid.
- the first syringe 12a and the second syringe 12b have substantially the same configuration except that their outer diameters and excluded volumes are different.
- the second syringe 12b will be described with reference to the reference numerals (numbers) of the corresponding components of the first syringe 12a, and detailed description thereof will be omitted.
- the first syringe 12a includes an outer cylinder (cylinder) 20a having a reduced-diameter flow port (discharge port) 18a provided at the tip, a gasket 22a that can be slid in a liquid-tight manner within the outer cylinder 20a, and a gasket 22a. And a pusher (plunger rod) 24a that moves in the axial direction of 20a.
- the circulation port 18a is an opening for allowing the liquid to flow inside and outside the outer cylinder 20a, and is a tapered tapered protrusion protruding from the front end surface of the outer cylinder 20a.
- a thin plate oval flange 26 is formed on the outer periphery of the base end edge of the outer cylinder 20a so as to put an index finger, a middle finger or the like when the operator operates the pusher 24a.
- the flange 26 is formed by the second syringe 12b. Is formed integrally with the outer periphery of the base end edge of the outer cylinder 20b.
- a guide member 28 that guides the forward and backward movement of the pushers 24a and 24b is fitted into the proximal end side opening of each of the outer cylinders 20a and 20b. You may provide the scale (not shown) which shows a liquid quantity in the outer peripheral surface of the outer cylinder 20a (20b).
- the material of the outer cylinder 20a (20b) is not particularly limited.
- polypropylene, cyclic polyolefin, polyester, and the like are preferable.
- the outer cylinder 20a is transparent or semi-transparent in order to ensure internal visibility.
- the pusher 24a is a long rod whose cross section orthogonal to the axial direction is formed in a cross shape, and a cross-shaped guide hole (not shown) penetrating the first syringe 12a side of the guide member 28 in the axial direction. Is inserted. Similarly, the pusher 24b is inserted through a cross-shaped guide hole (not shown) that penetrates the second syringe 12b side of the guide member 28 in the axial direction.
- the bases of the pushers 24a and 24b are integrally connected by a bridge 24c, and are configured in a substantially U shape as a whole. That is, the advance / retreat operation of the pushers 24a, 24b is integrated by a common operation portion (operation disk) 24d provided in the bridge 24c.
- the material of the pusher 24a (24b) may be the same as that of the outer cylinder 20a described above. However, in order to improve the visibility in the transparent outer cylinder 20a, it is preferable that the material is non-transparent.
- the gasket 22a is formed of, for example, an elastic material, and is a piston that can be liquid-tightly slidable in close contact with the inner peripheral surface of the outer cylinder 20a by being connected to the tip of the pusher 24a.
- the gasket 22a can suck and fill the liquid from the flow port 18a into the chamber formed on the tip side, and can push the filled liquid from the flow port 18a.
- the material of the gasket 22a (22b) is not particularly limited.
- various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, polyamide
- elastic materials such as various thermoplastic elastomers such as olefins and styrenes, or mixtures thereof.
- the 2nd syringe 12b is the structure substantially the same as the above-mentioned 1st syringe 12a, is equipped with the distribution port 18b, the outer cylinder 20b, the gasket 22b, and the pusher 24b, and the flange 26 and the guide member 28 are made into 1st. It is shared with the syringe 12a.
- the first syringe 12 a and the second syringe 12 b are connected at the base end side by a flange 26, and a portion from the center to the tip end is connected by a flat plate-like connecting portion 30.
- the connecting portion 30 is provided with a hook member 34 constituting an engagement mechanism (lock mechanism) 32 that locks and unlocks the nozzle 14 when the nozzle 14 is attached to and detached from the syringe 12.
- the engagement mechanism 32 includes a hook member 34 and a claw member 36 on the nozzle 14 side with which the hook member 34 is engaged.
- the hook member 34 includes a main body portion 38 and a thin plate-like elastic piece (elastic body) 40 extending obliquely downward from the base end of the main body portion 38.
- the elastic piece 40 is a leaf spring-like member that is curved toward the inner surface side, and whose end is landed on the connecting portion 30 and is slidable on the connecting portion 30, and the main body with the pin 42 as a rotation axis. The tip of the part is biased in the direction of swinging downward.
- the 1st liquid with which the 1st syringe 12a is filled, and the 2nd liquid with which the 2nd syringe 12b is filled are suitably according to the use of the said applicator 10, an intended purpose, etc.
- one of the first liquid and the second liquid is one containing thrombin (solution or the like), and the other contains fibrinogen.
- a liquid (solution etc.) can be mentioned.
- one of the first liquid and the second liquid is a liquid (solution or the like) containing carboxymethyldextrin modified with a succinimidyl group
- the other includes a liquid (solution or the like) containing disodium hydrogen phosphate.
- the first liquid and the second liquid in such a combination are altered, that is, gelled (solidified) when they are mixed.
- gelling for example, a liquid medicine (a mixture, a mixed solution) in which a liquid and a liquid are mixed can be reliably retained in an applied biological tissue (target site).
- the function as an adhesion preventing material can be surely exhibited.
- the types and combinations of the first liquid and the second liquid are not limited to those exemplified above.
- the cylinder 86 shown as one configuration example of the gas supply source is filled with a high-pressure (compressed) sterile gas (hereinafter simply referred to as “gas”) in its internal space, and the gas is applied to the applicator 10 ( It can be supplied (sent) to the nozzle 14).
- gas a high-pressure (compressed) sterile gas
- carbon dioxide may be used as the gas.
- the cylinder 86 is provided with an openable / closable valve (cock) 87 for controlling supply / stop of gas supply to the applicator 10. When the applicator 10 is used, the valve 87 is opened.
- the nozzle 14 includes a long nozzle body 74, a nozzle support portion (housing) 76 that supports the base end portion of the nozzle body 74, and a nozzle head 78 provided at the tip of the nozzle body 74.
- the nozzle support portion 76 is made of, for example, a metal material or a resin material, and the outer shape forms a block shape.
- the nozzle support portion 76 is a member made of, for example, a metal material or a resin material, has a substantially triangular shape that is tapered in a plan view, and a circular opening 76a through which the nozzle body 74 is inserted is formed at the tip thereof.
- This is a box-shaped member in which a rectangular opening (not shown) is formed at the base end so that the flow path member 64 can be projected and retracted.
- a flow path member 64 that can be moved forward and backward is disposed inside the nozzle support portion 76.
- Connection ports 62 a and 62 b into which the respective flow ports 18 a and 18 b of the syringe 12 are fitted are formed on the base end surface of the flow path member 64.
- An outlet port 67 into which the proximal end portion of the nozzle body 74 is inserted and connected projects from the distal end surface of the flow path member 64, and a gas into which the tube 86a from the cylinder 86 is inserted and connected to the lower surface.
- a port (not shown) is provided.
- a first nozzle liquid channel (not shown) through which the first liquid supplied from the first syringe 12a flows, and a second nozzle (not shown) through which the second liquid supplied from the second syringe 12b flows.
- a two-nozzle liquid channel and a nozzle gas channel (not shown) through which the gas supplied from the cylinder 86 flows are provided.
- the first and second nozzle liquid flow paths extend in the tip direction in the nozzle body 74 and then merge with each other in a merge flow path 58 (see FIG. 2) disposed in the nozzle head 78.
- Each nozzle liquid flow path is integrally joined at the base end of the merge flow path 58 with each nozzle liquid flow path, so that the liquid and the liquid can be mixed uniformly and reliably.
- the nozzle head 78 has a cylindrical outer shape, and has an injection port 72 that opens at the tip wall portion 79.
- the tip of the combined flow path 58 is connected to the injection port 72.
- the ejection port 72 is an opening for discharging the mixture of the first liquid, the second liquid, and the gas mixed in the combined flow path 58.
- a constituent material of the nozzle head 78 For example, the same thing as the constituent material of the nozzle support part 76 can be used.
- the nozzle gas flow path through which the gas flows is constituted by the lumen of the nozzle main body 74 which is an outer tube connected to the outlet port 67 of the flow path member 64, and the first and second nozzle liquid flow paths and the combined flow path 58.
- the portion arranged as an inner tube it is constituted by a gap formed around these.
- the wall surface of the combined flow path 58 is formed of a gas permeable membrane through which gas can pass and liquid cannot pass, so that the gas that has circulated through the nozzle gas flow path flows into the inside from the tube wall of the combined flow path 58. .
- the liquid mixture which flows through the combined flow path 58 is atomized by being injected from the injection port 72 together with the gas flowing in from the surroundings, and is uniformly applied to the target site (affected part).
- the nozzle body 74 is formed of a long tubular body, and connects the distal end portion of the nozzle support portion 76 and the proximal end of the nozzle head 78.
- the nozzle body 74 has a curved portion 84 that is curved or bent at the tip (tip side) and has flexibility (softness).
- the bending portion 84 is bent or bent so that the tip thereof faces obliquely upward.
- the axis a ⁇ b> 2 of the nozzle head 78 is relative to the axis of the nozzle main body 74 (strictly, the axis of the portion on the proximal end side of the curved portion 84 of the nozzle main body 74) a ⁇ b> 1.
- the inclination angle ⁇ of the axis a2 of the nozzle head 78 with respect to the axis a1 of the nozzle body 74 when the bending portion 84 is bent or bent without being regulated by the sheath 21 hereinafter referred to as “maximum inclination angle ⁇ MAX”). Is preferably about 30 to 90 °, more preferably about 45 to 70 °.
- the curved portion 84 of the nozzle body 74 is made of a soft material, an elastic material, or the like. Further, the proximal end portion of the nozzle body 74 from the curved portion 84 may be made of a hard material, or may be made of a soft material, an elastic material, or the like and have flexibility.
- the curved portion 84 and the portion of the nozzle body 74 on the proximal end side with respect to the curved portion 84 may be configured by separate members, and may be fixed by adhesion, fusion, or the like, or may be integrally formed. Also good.
- the constituent material of the nozzle body 74 is not particularly limited.
- various soft or hard resins such as polyvinyl chloride, various rubber materials such as natural rubber and butyl rubber, various heat such as polyurethane and polyester.
- Various metal materials such as plastic elastomer, stainless steel, aluminum, copper or copper alloy, and various ceramics such as various glasses, alumina, silica and the like. Any of these can be used for the portion of the nozzle body 74 on the proximal end side with respect to the curved portion 84, and a soft material or an elastic material can be used for the curved portion 84.
- the applicator 10 further includes a sheath (elongate tube) 21 that functions as a shape regulating member that regulates the shape of the curved portion 84 of the nozzle body 74.
- a nozzle body 74 is inserted (inserted) into the sheath 21 (through hole of the sheath 21), and the sheath 21 extends along the longitudinal direction (axial direction) of the nozzle body 74 with respect to the nozzle body 74. It can be moved.
- the sheath 21 may be inserted into the sheath 21 so that at least the curved portion 84 of the nozzle body 74 is inserted. In this embodiment, the sheath 21 is inserted to the vicinity of the proximal end portion of the nozzle body 74. It has become.
- the sheath 21 is made of a hard material so that the shape of the curved portion 84 can be regulated, and it is desirable that the sheath 21 has necessary and sufficient rigidity, and further has low slidability.
- the constituent material of the sheath 21 include hard resins such as polyolefin resins such as polyethylene and polypropylene, various metal materials such as stainless steel, aluminum, copper, and copper alloys, and various ceramics such as various glasses, alumina, and silica. It is done.
- the shape of the curved portion 84 is changed by adjusting the protruding length of the curved portion 84 from the distal end of the sheath 21 by holding the sheath 21 and moving it in the axial direction.
- the inclination angle ⁇ of the axis a2 of the nozzle head 78 with respect to the axis a1 of the nozzle body 74 can be adjusted.
- the sheath 21 is in a state where the curved portion 84 is bent or bent without being regulated by the sheath 21, and the non-regulated position (first position) where the axis a ⁇ b> 1 of the nozzle body 74 is inclined with respect to the axis a ⁇ b> 2 of the nozzle head 78.
- the curved portion 84 is straightened (restricted) by the sheath 21 and becomes a straight line between the restriction position (second position) where the direction of the axis a2 of the nozzle head 78 and the direction of the axis a1 of the nozzle body 74 coincide. It can move.
- the entire bending portion 84 protrudes from the distal end of the sheath 21, and the bending portion 84 is bent or bent without being restricted by the sheath 21. It has become a state. At this time, the end portion 21a of the sheath 21 and the stepped portion 76b of the nozzle support portion 76 are in contact with each other, and the sheath 21 is positioned at the non-regulating position.
- the inclination angle ⁇ gradually decreases as the sheath 21 is moved in the distal direction.
- the entire bending portion 84 is inserted into the sheath 21 as shown in FIG. 4B, and the bending portion 84 is corrected by the sheath 21 and becomes linear.
- the stepped portion 76c provided in the nozzle support portion 76 and the projection 21b provided at or near the proximal end portion of the sheath 21 come into contact with each other, and the sheath 21 stops (positions) at the restriction position. . Note that when the sheath 21 is located at the restriction position, the nozzle head 78 protrudes from the distal end of the sheath 21.
- the operation for adjusting the tilt angle ⁇ may be performed concurrently with the operation for ejecting (ejecting) the first liquid and the second liquid, or the operation for ejecting the first liquid and the second liquid. It may be performed later or may be performed before the operation of ejecting the first liquid and the second liquid. Alternatively, the operation for adjusting the tilt angle ⁇ may be performed first, then the operation for ejecting the first liquid and the second liquid may be started, and then the operation for further adjusting the tilt angle ⁇ may be performed. .
- a finger for example, an index finger and a middle finger
- another finger for example, a thumb
- the operation unit 24d is mounted on the flange.
- the applicator 10 As shown in FIGS. 1 to 3, the applicator 10 according to the present embodiment is provided at the tip of the nozzle 14, and the irradiation unit 100 that emits light that is directed toward the tip of the nozzle 14 and diffuses, A power supply unit 101 that supplies power to the irradiation unit 100 and conductive wires (conductive members) 103 a and 103 b that guide current from the power supply unit 101 to the light source 102 are further provided.
- the irradiation unit 100 is provided at the tip of the nozzle 14 (nozzle head 78), and the light source 102 that generates illumination light and the light from the light source 102 is circular diffused light that is directed toward the tip of the nozzle 14.
- a lens 104 With such a configuration, the diffused light is irradiated in the direction in which the nozzle 14 is directed by the irradiation unit 100 provided at the tip of the nozzle 14. That is, light is irradiated to a target site where a drug (chemical solution) is to be applied.
- the irradiation unit 100 is disposed inside the curved shape of the curved portion 84 at the tip of the nozzle 14.
- the lens 104 constituting the most distal portion of the irradiation unit 100 is disposed at a position higher than the tip of the nozzle 14.
- a light emitting diode LED
- LD semiconductor laser
- a light bulb or the like
- the light emitting diode and the semiconductor laser can be configured to be small and light, they are suitable as the light source 102 provided in the nozzle head 78 that is desired to be small.
- the color of light generated by the light source 102 is not particularly limited as long as it is visible light, and examples thereof include white and light pink.
- the light emitted from the light source 102 is light of a color opposite to that of the organ, such as blue or green, it is easy to see the light irradiated to the target site, and the applied (sprayed) drug (for example, adhesion) Easy to identify.
- the light source 102 and the lens 104 are held by a holding member 106 and fixed to the nozzle head 78.
- the holding member 106 includes a pair of arm portions 108 a and 108 b extending opposite to each other, and a connecting portion 110 that connects the arm portions 108 a and 108 b, and is substantially U-shaped as a whole. It is a member having a shape, and is fixed to the nozzle head 78 by elastically holding the nozzle head 78 from both sides by a pair of arm portions 108a and 108b.
- the light source 102 and the lens 104 are provided in the connecting portion 110.
- the nozzle head 78 may be configured to hold the light source 102 and the lens 104 by the nozzle head 78 itself, instead of providing the independent holding member 106 as described above.
- the conducting wires 103 a and 103 b are electrically connected to the light source 102 and the power supply unit 101, and are disposed along the nozzle body 74 through the inside of the sheath 21. In other words, at least a part of the conducting wires 103 a and 103 b is covered and protected by the sheath 21. Further, as shown in FIGS. 1 and 2, when the nozzle body 74 and the conductors 103a and 103b are covered together with the tubular covering member 112, and the nozzle body 74 covered with the covering member 112 in this way is inserted into the sheath 21, Good.
- the covering member 112 is provided in a range from the vicinity of the curved portion 84 of the nozzle body 74 to the vicinity of the base end portion, and can be formed of, for example, a heat shrinkable tube.
- the conducting wires 103 a and 103 b penetrate the wall portion of the nozzle support portion 76, extend outside the nozzle support portion 76 in the form of a single cable 105, and are electrically connected to the power supply portion 101.
- the power supply unit 101 is, for example, a battery box that houses a battery, and is provided with a switch 114 that switches the power supply unit 101 on and off. When the power of the power supply unit 101 is turned on by operating the switch 114, current is supplied to the light source 102 through the conductive wires 103a and 103b, and the light source 102 emits light.
- the length of the cable 105 is such that the user holds the nozzle 14 and the syringe 12 by hand and puts the power supply unit 101 in a storage part (such as a pocket) provided in the user's clothes or hooks the user's clothes. In such a case, the length is sufficient to prevent the user from using the applicator 10.
- the power supply unit 101 is configured to be separated from the nozzle 14 and the syringe 12, it is not necessary for the user to have a weight including the power supply unit 101 when using the applicator 10, and usability is improved. Good.
- an adapter that can be connected to an external power supply may be provided, and power may be supplied to the light source 102 by the external power supply.
- an opening 124 for inserting the nozzle 14 is formed by leaving about 2 to 3 cm of the incised portion without sewing.
- the peritoneum 120 is grasped by grasping means (for example, forceps, gripper, etc.) 118, and the peritoneum 120 is lifted so that the peritoneum 120 and the organ 121 do not contact each other.
- the power supply unit 101 is operated to cause the light source 102 of the irradiation unit 100 to emit light, and the nozzle 14 of the applicator 10 is inserted into the abdominal cavity 119. And the nozzle 14 is arrange
- the tip portion (nozzle head 78) of the nozzle 14 cannot be directly viewed.
- the peritoneum 120 is thin, the light from the irradiation unit 100 is transmitted. A part penetrates the peritoneum 120. For this reason, the illuminated part can be visually recognized from the outside.
- the direction which the irradiation part 100 illuminates and the discharge direction of the adhesion prevention material from the nozzle 14 are substantially corresponded. . Therefore, the direction of the tip of the nozzle 14 can be predicted from the irradiation site that can be visually recognized from the outside.
- diffused light emitted from the irradiation unit 100 (hereinafter referred to as “diffused light” will be described with reference to “L” in the case of referring to FIG. 5) and an adhesion preventing material (hereinafter referred to as “diffused light”).
- the “adhesion prevention material” will be described with a symbol M), both of which are divergent, so that the spread of the diffused light L and the discharged adhesion prevention material M It is good to make the extent of spread substantially coincide.
- the nozzle 14 (specifically, the nozzle head 78) is set so that the diffusion diameter of the adhesion preventing material M discharged from the nozzle 14 and the diffusion diameter of the diffused light L emitted from the irradiation unit 100 substantially coincide.
- the irradiation part 100 is good to comprise.
- the diameter is 2.5 cm at an irradiation distance of 2 cm.
- the irradiation unit 100 is configured to emit light having a diameter of 3 to 3.5 cm at an irradiation distance of 5 cm. If comprised in this way, the distance from an irradiation site
- the irradiation site comes to the target site and the size of the irradiation site becomes a desired spray diameter (for example, 2.5 to 3.5 cm).
- the position and orientation of the nozzle 14 are adjusted. Once adjusted in this manner, the adhesion preventing material M is discharged from the tip of the nozzle 14 by pressing the operation portion 24d toward the tip. Thereby, the adhesion prevention material M can be reliably apply
- the spraying range of the adhesion preventing material M can be accurately predicted by the size of the light diffusion diameter, the adhesion preventing material M can be easily applied to a desired range.
- the position of the nozzle 14 is adjusted so that the irradiation site moves toward the opening 124 along the stitching portion 122 while maintaining the size of the irradiation site.
- the anti-adhesive material M is applied.
- the irradiation unit 100 is disposed inside the curved shape of the curved portion 84, when the adhesion preventing material M is discharged with the nozzle 14 facing upward, adhesion is performed from the tip of the nozzle 14.
- the irradiation unit 100 is positioned on the side opposite to the side on which the prevention material M is likely to sag, and the adhesion prevention material M is unlikely to adhere to the irradiation unit 100. Therefore, the irradiation unit 100 (in particular, the lens 104) is not shielded by the adhesion preventing material M, and the irradiation unit 100 can reliably irradiate light in the direction in which the tip of the nozzle 14 is directed.
- the irradiation part 100 is arrange
- the irradiation unit 100 is positioned on the axis line. Therefore, the position where the tip of the nozzle 14 is directed can be easily aligned with the position of the stitching portion 122, and the adhesion preventing material M can be applied more accurately at a desired target position.
- the first application method is an application method in which a drug (adhesion prevention material M) is ejected and applied to a target site, and is a hole formed in a membranous tissue (peritoneum 120) covering a living body organ 121.
- the step of inserting the tip of the nozzle 14 of the applicator 10 into the space (abdominal cavity 119) between the organ 121 and the membranous tissue, and the membranous tissue from the back side of the membranous tissue In contrast, the step of irradiating the diffused light L that is directed and diffused toward the tip of the nozzle 14 and the position and orientation of the nozzle 14 so that the irradiated part of the diffused light L with respect to the membranous tissue comes to the application target part. And a step of discharging the medicine from the tip portion of the nozzle 14.
- a predetermined surgical process for example, incision, excision, cauterization, suturing, etc.
- 100 light sources 102 are caused to emit light, and the nozzle 14 is inserted into the abdominal cavity.
- the size of the irradiation site is adjusted to a desired spray diameter (for example, 2.5 to 3.5 cm). Adjust position and orientation.
- the operation part 24d is pressed to the tip side to discharge (spray) the adhesion preventing material M from the tip of the nozzle 14.
- the adhesion preventing material can be reliably applied to the target site.
- the spray range of the adhesion preventing material can be accurately predicted by the size of the light diffusion diameter, the adhesion preventing material can be easily applied to a desired range.
- the target site has become the color of the adhesion preventing material (for example, white if the adhesion preventing material is white)
- the ejection of the adhesion preventing material is terminated.
- the pneumothorax is terminated by a normal method, and the operation is completed.
- the second application method is an application method in which a drug (adhesion prevention material M) is discharged and applied to a target site, and the tip of the nozzle 14 of the applicator 10 is passed through a hole formed in the abdominal wall of the living body. Is inserted into the abdominal cavity 119 of the living body, the living tissue in the abdominal cavity 119 is irradiated with diffused light L that is directed and diffused toward the tip of the nozzle 14, and the abdominal cavity 119 is passed through the laparoscope.
- a drug adheresion prevention material M
- the applicator 10 by providing the irradiation unit 100 that emits divergent light at the tip of the nozzle 14, the position and size (diameter) of the light at the irradiation site. ), The direction of the tip of the nozzle 14 and the distance from the object can be grasped, and thereby the adhesion preventing material can be reliably applied to the target site.
- the light source 102 is provided at the tip of the nozzle 14, and light is irradiated in the tip direction of the nozzle 14 by guiding current to the light source 102 through the conductive wires 103 a and 103 b disposed along the nozzle body 74.
- the configuration can be made inexpensively.
- the adhesion preventing material M can be prevented from adhering to the irradiation unit 100, and the position where the tip of the nozzle 14 is oriented is sewn. It can be easily fitted to the part 122 (incision) or the wound.
- the conductors 103a and 103b are disposed inside the sheath 21 which is a member for regulating the shape of the curved portion 84 of the nozzle 14, and the conductors 103a and 103b are thereby covered with the sheath 21. Therefore, the conducting wires 103a and 103b can be easily and well wired along the nozzle 14.
- the color of light emitted from the light source 102 may have a wavelength that is easily absorbed by the adhesion preventing material.
- the brightness of the irradiated part when viewed from the outside changes depending on the amount of application, it is possible to easily grasp how much the adhesion preventing material has been applied using the brightness as an index.
- the adhesion preventing material can be uniformly applied along the stitched portion 122 (coating unevenness can be reduced), and the amount of the adhesion preventing material used can be reduced.
- each fixture 130 has a shape in which a part of a circle is cut out in an angle range of less than 180 degrees, and a recess 132 is formed in the inner peripheral portion thereof.
- the fixing tool 130 can be elastically deformed to widen the distance between both ends, and in a natural state (a state where no external force is applied), the distance between both ends is smaller than the outer diameter of the sheath 21.
- a fixture 130 can be made of various metals, alloys, resins, etc. having elasticity.
- a plurality of fixtures 130 configured as described above are attached to the sheath 21 with the conductors 103a and 103b inserted into the recesses 132, whereby the conductors 103a and 103b are integrated with the outer periphery of the sheath 21. Fixed.
- the applicator 140 shown in FIG. 7 includes an irradiation unit 142, an optical fiber (light guide member) 144, and a light source 146.
- the irradiation unit 142 includes a lens 104, and the lens 104 is held by a holding member 106 a and fixed to the nozzle head 78. That is, unlike the irradiation unit 100 in the first embodiment, the irradiation unit 142 in the second embodiment does not include a light source. Instead, the light source 146 is disposed on the nozzle support unit 76 and emitted from the light source 146. Light is guided to the lens 104 by an optical fiber 144 disposed along the nozzle body 74.
- the holding member 106a is configured to be smaller than the holding member 106 shown in FIG.
- the light introduced into the lens 104 by the optical fiber 144 is turned into divergent light (diffused light) by the lens 104 and is irradiated toward the tip of the nozzle 14.
- the spread of the diffused light emitted from the irradiation unit 142 is set to be the same as that emitted from the irradiation unit 100 in the first embodiment.
- the optical fiber 144 shown in FIG. 7 is arranged so as to pass through the inside of the sheath 21 by being covered with the covering member 112, similarly to the wiring structure of the conducting wires 103a and 103b shown in FIG. Instead of the structure, it may be fixed to the sheath 21 along the outer peripheral portion of the sheath 21 by a plurality of fixtures 130 as in the wiring structure shown in FIG.
- the light source 146 a semiconductor laser, a light emitting diode, a light bulb, or the like can be used.
- the light source 102 is electrically connected to the power supply unit 101 via the cable 148.
- the switch 114 of the power supply unit 101 When the switch 114 of the power supply unit 101 is turned on, power is supplied to the light source 102 to emit light.
- the light from the light source 102 is introduced into the lens 104 through the optical fiber 144 as described above, is converted into diffused light by the lens 104, and is irradiated toward the tip of the nozzle 14.
- the irradiation unit 142 that emits divergent light at the tip of the nozzle 14
- the position and size (diameter) of the light at the irradiation site can be used.
- the direction of the tip and the distance from the object can be grasped, and thereby the adhesion preventing material can be reliably applied to the target site.
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Abstract
Description
Claims (7)
- 薬剤を吐出して目的部位に塗布する塗布具(10、140)であって、
塗布具本体(12)と、
前記塗布具本体(12)から延出したノズル(14)と、
前記ノズル(14)の先端部に設けられ、前記ノズル(14)の先端方向を指向し且つ拡散する光を出射する照射部(100、142)とを備える、
ことを特徴とする塗布具(10、140)。 - 請求項1記載の塗布具(10、140)において、
前記ノズル(14)は、前記塗布具本体(12)から延出するとともに先端側に湾曲部(84)を有する長尺状のノズル本体(74)と、前記ノズル本体(74)の先端に設けられたノズルヘッド(78)とを有し、
前記照射部(100、142)は、前記湾曲部(84)の湾曲形状の内側に配置されている、
ことを特徴とする塗布具(10、140)。 - 請求項1記載の塗布具(10、140)において、
前記ノズル(14)は、前記薬剤を噴霧するように構成され、
前記ノズル(14)から吐出される薬剤の拡散径と、前記照射部(100、142)から出射される光の拡散径とが略一致する、
ことを特徴とする塗布具(10、140)。 - 請求項1記載の塗布具(10)において、
前記照射部(100)は光源(102)を有し、
前記ノズル(14)に沿って、前記光源(102)に電源部(101)からの電流を導く導電部材(103a、103b)が配設される、
ことを特徴とする塗布具(10)。 - 請求項4記載の塗布具(10)において、
前記ノズル(14)は、前記塗布具本体(12)から延出するとともに先端側に可撓性の湾曲部(84)を有する長尺状のノズル本体(74)と、前記ノズル本体(74)の先端に設けられたノズルヘッド(78)とを有し、
前記塗布具(10)は、前記ノズル本体(74)の長手方向に沿って移動可能に設けられるとともに長手方向の位置に応じて前記湾曲部(84)の形状を変化させる形状規制部材(21)をさらに備え、
前記導電部材(103a、103b)は、前記形状規制部材(21)の内側を通して配設される、
ことを特徴とする塗布具(10)。 - 請求項1記載の塗布具(140)において、
前記照射部(142)は、光を拡散させるレンズ(104)により構成され、
前記ノズル(14)に沿って、前記レンズ(104)に光源(146)からの光を導く導光部材(144)が配設される、
ことを特徴とする塗布具(140)。 - 請求項6記載の塗布具(140)において、
前記ノズル(14)は、前記塗布具本体(12)から延出するとともに先端側に可撓性の湾曲部(84)を有する長尺状のノズル本体(74)と、前記ノズル本体(74)の先端に設けられたノズルヘッド(78)と備え、
前記塗布具(140)は、前記ノズル本体(74)の長手方向に沿って移動可能に設けられるとともに長手方向の位置に応じて前記湾曲部(84)の形状を変化させる形状規制部材(21)をさらに備え、
前記導光部材(144)は、前記形状規制部材(21)の内側を通して配設される、
ことを特徴とする塗布具(140)。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
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JP2013500917A JP5917484B2 (ja) | 2011-02-25 | 2012-01-05 | 塗布具 |
EP12749692.5A EP2679170A4 (en) | 2011-02-25 | 2012-01-05 | APPLICATOR |
US13/967,092 US9149587B2 (en) | 2011-02-25 | 2013-08-14 | Sprayer |
Applications Claiming Priority (2)
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JP2011-039160 | 2011-02-25 | ||
JP2011039160 | 2011-02-25 |
Related Child Applications (1)
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US13/967,092 Continuation US9149587B2 (en) | 2011-02-25 | 2013-08-14 | Sprayer |
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WO2012114781A1 true WO2012114781A1 (ja) | 2012-08-30 |
Family
ID=46720571
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PCT/JP2012/050047 WO2012114781A1 (ja) | 2011-02-25 | 2012-01-05 | 塗布具 |
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US (1) | US9149587B2 (ja) |
EP (1) | EP2679170A4 (ja) |
JP (1) | JP5917484B2 (ja) |
WO (1) | WO2012114781A1 (ja) |
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US11272953B2 (en) | 2016-04-05 | 2022-03-15 | Cilag Gmbh International | Articulation joint for surgical instrument |
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US9763743B2 (en) * | 2014-07-25 | 2017-09-19 | Arrinex, Inc. | Apparatus and method for treating rhinitis |
USD877890S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution device |
USD877891S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution and delivery device |
US10918790B2 (en) * | 2015-12-22 | 2021-02-16 | Guangzhou Bioseal Biotech Co., Ltd. | Dual syringe with funnel feeding kit |
US10959714B2 (en) * | 2018-04-19 | 2021-03-30 | Ethicon, Inc. | Dual syringe cartridge and housing |
KR102453400B1 (ko) * | 2020-06-25 | 2022-10-11 | (주)세원메디텍 | 자가혈 치료술용 포터블 스프레이장치 |
US20220193342A1 (en) * | 2020-12-18 | 2022-06-23 | Ethicon, Inc. | Dual cartridge container applicator with needle penetration connection to tip |
US20230309978A1 (en) * | 2022-03-31 | 2023-10-05 | Ethicon, Inc. | Sealant applicators having mixing and spraying assemblies with malleable sections and spray tips having reduced dimensions |
CN116832277B (zh) * | 2023-08-30 | 2023-11-17 | 上海埃立孚医疗科技有限公司 | 一种一次性雾化注射给药器 |
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Also Published As
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US20130331658A1 (en) | 2013-12-12 |
US9149587B2 (en) | 2015-10-06 |
EP2679170A4 (en) | 2015-06-24 |
JP5917484B2 (ja) | 2016-05-18 |
JPWO2012114781A1 (ja) | 2014-07-07 |
EP2679170A1 (en) | 2014-01-01 |
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