WO2012088620A3 - Concentrado de omega 3 - Google Patents

Concentrado de omega 3 Download PDF

Info

Publication number
WO2012088620A3
WO2012088620A3 PCT/CL2011/000082 CL2011000082W WO2012088620A3 WO 2012088620 A3 WO2012088620 A3 WO 2012088620A3 CL 2011000082 W CL2011000082 W CL 2011000082W WO 2012088620 A3 WO2012088620 A3 WO 2012088620A3
Authority
WO
WIPO (PCT)
Prior art keywords
mixture
fatty acid
liquid phase
placing
liquid
Prior art date
Application number
PCT/CL2011/000082
Other languages
English (en)
French (fr)
Other versions
WO2012088620A2 (es
Inventor
Juvenal Antonio SEPÚLVEDA REYES
Miriam Rosa BERRIOS CORNEJO
Miguel Ángel FUENZALIDA DÍAZ
Alejandro Markovits Rojas
Thomas Francis Harting Glade
Original Assignee
Golden Omega S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45606887&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2012088620(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to US13/994,785 priority Critical patent/US8957231B2/en
Priority to CN201180062711.6A priority patent/CN103281910B/zh
Priority to JP2013543482A priority patent/JP5861968B2/ja
Priority to ES11817504T priority patent/ES2716817T5/es
Priority to AU2011350073A priority patent/AU2011350073C1/en
Application filed by Golden Omega S.A. filed Critical Golden Omega S.A.
Priority to DK11817504.1T priority patent/DK2659780T3/en
Priority to EP11817504.1A priority patent/EP2659780B2/en
Priority to KR1020137013031A priority patent/KR101506412B1/ko
Priority to CA2822314A priority patent/CA2822314C/en
Publication of WO2012088620A2 publication Critical patent/WO2012088620A2/es
Publication of WO2012088620A3 publication Critical patent/WO2012088620A3/es
Priority to MA35967A priority patent/MA34715B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining
    • C11C1/10—Refining by distillation
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/08—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with fatty acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un proceso eficiente y simple para obtener un concentrado que comprende sobre 80% en peso de etil ésteres de ácidos grasos ω-3 a partir de una composición de materia que contiene ésteres de ácidos grasos ω-3 o ácidos grasos ω-3 libres, que comprende las etapas de: a) contactar la composición de materia con etanol de al menos 96% en peso y un hidróxido de un metal alcalino a una temperatura entre 60 y 200 °C para formar una mezcla líquida que comprende sales alcalinas de ácidos grasos; b) enfriar la mezcla líquida hasta una temperatura entre 50 y -20 °C para formar una fase sólida y una fase líquida y separar la fase líquida de la fase sólida; c) contactar la fase líquida separada de la etapa b) con un ácido para formar una mezcla acidificada con un contenido de agua menor a 10%, donde la mezcla consiste en una fase sólida que comprende la sal alcalino metálica del ácido y una fase líquida que comprende ácidos grasos ω-3; d) calentar la mezcla de la etapa c) entre 50 a 150 °C en presencia de un catalizador de esterificación para formar una mezcla que comprende ésteres etílicos de ácidos grasos ω-3; e) contactar la mezcla de la etapa d) con un álcali para formar una mezcla neutralizada; f) destilar la mezcla neutralizada para obtener un destilado que comprende sobre 80% en peso de ésteres etílicos de ácidos grasos ω-3.
PCT/CL2011/000082 2010-12-27 2011-12-25 Concentrado de omega 3 WO2012088620A2 (es)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CA2822314A CA2822314C (en) 2010-12-27 2011-12-25 Concentrate of omega 3
CN201180062711.6A CN103281910B (zh) 2010-12-27 2011-12-25 ω-3的浓缩物
JP2013543482A JP5861968B2 (ja) 2010-12-27 2011-12-25 オメガ３濃縮物を得るための方法
ES11817504T ES2716817T5 (es) 2010-12-27 2011-12-25 Concentrado de omega 3
AU2011350073A AU2011350073C1 (en) 2010-12-27 2011-12-25 Omega-3 concentrate
US13/994,785 US8957231B2 (en) 2010-12-27 2011-12-25 Concentrate of omega 3
DK11817504.1T DK2659780T3 (en) 2010-12-27 2011-12-25 Omega 3 concentrate
EP11817504.1A EP2659780B2 (en) 2010-12-27 2011-12-25 Omega 3 concentrate
KR1020137013031A KR101506412B1 (ko) 2010-12-27 2011-12-25 오메가 3의 농축물
MA35967A MA34715B1 (fr) 2010-12-27 2013-06-05 Concentre d'omega 3

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CL2010001587A CL2010001587A1 (es) 2010-12-27 2010-12-27 Proceso de preparacion de un concentrado de etil esteres de acidos grasos omega-3 que comprende sobre el 80% en peso de dichos esteres en configuracion cis y sus dobles enlaces separados por una unidad metilenica.
CL1587-2010 2010-12-27

Publications (2)

Publication Number Publication Date
WO2012088620A2 WO2012088620A2 (es) 2012-07-05
WO2012088620A3 true WO2012088620A3 (es) 2012-09-13

Family

ID=45606887

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CL2011/000082 WO2012088620A2 (es) 2010-12-27 2011-12-25 Concentrado de omega 3

Country Status (14)

Country Link
US (1) US8957231B2 (es)
EP (1) EP2659780B2 (es)
JP (1) JP5861968B2 (es)
KR (1) KR101506412B1 (es)
CN (1) CN103281910B (es)
AU (1) AU2011350073C1 (es)
CA (1) CA2822314C (es)
CL (1) CL2010001587A1 (es)
CO (1) CO6710941A2 (es)
DK (1) DK2659780T3 (es)
ES (1) ES2716817T5 (es)
MA (1) MA34715B1 (es)
PE (1) PE20140810A1 (es)
WO (1) WO2012088620A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014054435A1 (ja) * 2012-10-01 2014-04-10 日清ファルマ株式会社 高度不飽和脂肪酸アルキルエステル含有組成物の製造方法
ITMI20121681A1 (it) * 2012-10-08 2014-04-09 Milanotrading Srl Metodo di produzione di esteri etilici di acidi grassi poliinsaturi e loro impiego in formulazioni per uso orale nell'uomo
WO2015154997A1 (en) * 2014-04-07 2015-10-15 Epax Norway As Long chain monounsaturated fatty acid composition and method for the production thereof
DK3294850T3 (da) * 2015-05-13 2021-01-04 Epax Norway As Meget langkædede polyumættede fedtsyrer fra naturlige olier
SG11201801589SA (en) 2015-08-31 2018-03-28 Nippon Suisan Kaisha Ltd Free-polyunsaturated-fatty-acid-containing composition and method for manufacturing same
JP6967334B2 (ja) * 2015-12-21 2021-11-17 備前化成株式会社 高度不飽和脂肪酸のエステルを含む組成物
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586641A1 (en) * 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) * 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
US20230002700A1 (en) * 2020-01-30 2023-01-05 Silicycle Inc. Process of producing magnesium salts of pufas and composition containing same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679809A (en) * 1994-05-09 1997-10-21 Nestec S.A. Concentrate of polyunsaturated fatty acid ethyl esters and preparation thereof
EP1211304A2 (en) * 2000-11-30 2002-06-05 Sepu Fine Chem Co., Ltd. Method for isolating high-purified unsaturated fatty acids using crystallization
WO2009020406A1 (en) * 2007-08-07 2009-02-12 Granate Seed Limited Methods of making lipid substances, lipid substances made thereby and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57149400A (en) * 1981-03-12 1982-09-14 Kureha Chemical Ind Co Ltd Manufacture of high purity long chain highly unsaturated fatty acid ester
DE3227669C1 (de) 1982-07-23 1983-07-07 Hermann Dr. 4400 Münster Stage Verfahren und Anlage zum Desodorieren und/oder Entsaeuern von Speiseoelen,Fetten und Estern
JPS5921641A (ja) 1982-07-28 1984-02-03 Kureha Chem Ind Co Ltd エイコサペンタエン酸およびドコサヘキサエン酸の濃縮分離法
GB8314496D0 (en) 1983-05-25 1983-06-29 Unilever Plc Treating triglyceride oil
US4792418A (en) 1985-08-14 1988-12-20 Century Laboratories, Inc. Method of extraction and purification of polyunsaturated fatty acids from natural sources
US4804555A (en) 1986-10-21 1989-02-14 General Mills, Inc. Physical process for simultaneous deodorization and cholesterol reduction of fats and oils
IT1205043B (it) 1987-05-28 1989-03-10 Innova Di Ridolfi Flora & C S Procedimento per l'estrazione di esteri di acidi grassi poliinsaturi da olii di pesce e composizioni farmaceutiche e dietetiche contenenti detti esteri
US4915876A (en) 1987-07-20 1990-04-10 General Mills, Inc. Process for the deodorization and stabilization of polyunsaturated oils
CN1013858B (zh) * 1988-03-26 1991-09-11 山东省海洋药物科学研究所 二十碳五烯酸和二十二碳六烯酸及其酯类的分离制备方法
US4874629A (en) 1988-05-02 1989-10-17 Chang Stephen S Purification of fish oil
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
GB9404483D0 (en) 1994-03-08 1994-04-20 Norsk Hydro As Refining marine oil compositions
IT1274734B (it) 1994-08-25 1997-07-24 Prospa Bv Composizioni farmaceutiche contenenti acidi grassi poliinsaturi, loro esteri o sali, unitamente a vitamine o provitamine antiossidanti
CN1204638A (zh) * 1997-07-02 1999-01-13 湖南天海林实业股份有限公司 二十二碳六烯酸的制备和酯化工艺
KR20040086004A (ko) * 2003-03-27 2004-10-08 임호빈 오메가-3 지방산을 함유하는 종속영양 클로렐라 및유가배양에 의한 이의 고농도 제조방법
ITMI20051560A1 (it) * 2005-08-10 2007-02-11 Tiberio Bruzzese Composizione di acidi grassi n-3 con elevata concentrazione di epa e-o dha e contenente acidi grassi n-6
FR2894772B1 (fr) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Procede d'enrichissement en dha
CL2009001343A1 (es) * 2009-06-02 2009-07-10 Golden Omega S A Proceso de obtencion concentrado de esteres de epa y dha a partir de aceite marino, que comprende agregar al aceite alcali y agua a menos de 100 grados celsius, agregar solvente, separar fase de refinado, agregar acido, separar la fase no acuosa y agregar alcohol y un catalizador a menos de 150 grados celsius, desolventilizar y destilar.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679809A (en) * 1994-05-09 1997-10-21 Nestec S.A. Concentrate of polyunsaturated fatty acid ethyl esters and preparation thereof
EP1211304A2 (en) * 2000-11-30 2002-06-05 Sepu Fine Chem Co., Ltd. Method for isolating high-purified unsaturated fatty acids using crystallization
WO2009020406A1 (en) * 2007-08-07 2009-02-12 Granate Seed Limited Methods of making lipid substances, lipid substances made thereby and uses thereof

Also Published As

Publication number Publication date
JP2013545857A (ja) 2013-12-26
DK2659780T3 (en) 2019-04-29
MA34715B1 (fr) 2013-12-03
CA2822314A1 (en) 2012-07-05
JP5861968B2 (ja) 2016-02-16
EP2659780B2 (en) 2021-06-23
ES2716817T5 (es) 2021-12-29
CA2822314C (en) 2016-01-05
WO2012088620A2 (es) 2012-07-05
EP2659780B1 (en) 2019-02-13
ES2716817T3 (es) 2019-06-17
AU2011350073A1 (en) 2013-05-23
AU2011350073C1 (en) 2015-01-29
CO6710941A2 (es) 2013-07-15
CN103281910B (zh) 2015-04-15
CL2010001587A1 (es) 2013-01-11
AU2011350073B2 (en) 2014-07-17
EP2659780A2 (en) 2013-11-06
KR101506412B1 (ko) 2015-04-07
US20130267600A1 (en) 2013-10-10
US8957231B2 (en) 2015-02-17
PE20140810A1 (es) 2014-07-11
CN103281910A (zh) 2013-09-04
KR20130084302A (ko) 2013-07-24

Similar Documents

Publication Publication Date Title
WO2012088620A3 (es) Concentrado de omega 3
WO2012173660A3 (en) Co - products from biofuel production processes and methods of making the same
MX2016002618A (es) Proceso para purificar una composicion acida que comprende acido 2-formil-furan-5-carboxilico y acido 2,5-furandicarboxilico.
WO2013081777A8 (en) Antimicrobial mixture of aldehydes, organic acids and organic acid esters
EA201490361A1 (ru) Способ получения пав на основе жирных ациламидокарбоновых кислот
WO2014172540A3 (en) Improved acrylic acid and acrylate ester from lactide process
AR125817A2 (es) Utilización de ácido sulfónico para la recuperación de glicerol procedente de la reacción de transesterificación de triglicéridos
WO2012171001A3 (en) Food products containing beta-glucans and omega-3 fatty acids
WO2012112841A3 (en) [1,2,4]oxadiazol-3-yl acid salts and crystalline forms and their preparation
BR112012024286B8 (pt) Processo para obtenção de um éster de ácido carboxílico
PH12019550109A1 (en) Method for producing acetic acid
PL408509A1 (pl) Sposób wytwarzania mieszaniny estrów etylowych roślinnych kwasów tłuszczowych o wysokiej zawartości izomerów cis
Pintilie et al. Fatty acid ethyl esters from refined ostrich oil
WO2014181345A3 (en) A composition for preparing terephthalic acid
TH2001003018A (th) การสร้างมูลค่าของเกลือโพแทสเซียมที่ถูกผลิตร่วมในกระบวนการหมัก
UA102798U (ru) Способ получения дизельного биотоплива из пальмового масла
UA102806U (ru) Способ получения дизельного биотоплива из масла горчицы
UA102855U (ru) Способ получения дизельного биотоплива из подсолнечного масла
UA102823U (ru) Способ получения дизельного биотоплива из касторового масла
UA102803U (ru) Способ получения дизельного биотоплива из льняного масла
UA102802U (ru) Способ получения дизельного биотоплива из льняного масла
TH109985A (th) กระบวนการต่อเนื่องสำหรับการเปลี่ยนกรดไขมันให้เป็นเอสเตอร์โดยเร่งปฏิกิริยาแบบไม่เป็นเนื้อเดียวกัน
CN107432459A (zh) 蔗糖乳化剂
UA102805U (ru) Способ получения дизельного биотоплива из масла горчицы
MY156279A (en) A method of producing biodiesel using oil containing high content of free fatty acids

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11817504

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 13105810

Country of ref document: CO

ENP Entry into the national phase

Ref document number: 20137013031

Country of ref document: KR

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2011350073

Country of ref document: AU

Date of ref document: 20111225

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 001331-2013

Country of ref document: PE

ENP Entry into the national phase

Ref document number: 2013543482

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 13994785

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2822314

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2011817504

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE