WO2012056225A1 - Appareil permettant de produire de l'oxygène singulet - Google Patents

Appareil permettant de produire de l'oxygène singulet Download PDF

Info

Publication number
WO2012056225A1
WO2012056225A1 PCT/GB2011/052066 GB2011052066W WO2012056225A1 WO 2012056225 A1 WO2012056225 A1 WO 2012056225A1 GB 2011052066 W GB2011052066 W GB 2011052066W WO 2012056225 A1 WO2012056225 A1 WO 2012056225A1
Authority
WO
WIPO (PCT)
Prior art keywords
photosensitiser
singlet oxygen
oxygen
substrate
led
Prior art date
Application number
PCT/GB2011/052066
Other languages
English (en)
Inventor
Michael Brailey
Original Assignee
Soe Health Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Soe Health Limited filed Critical Soe Health Limited
Publication of WO2012056225A1 publication Critical patent/WO2012056225A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B13/00—Oxygen; Ozone; Oxides or hydroxides in general
    • C01B13/02—Preparation of oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
    • B01J19/122—Incoherent waves
    • B01J19/127—Sunlight; Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J2219/0873—Materials to be treated
    • B01J2219/0875—Gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J2219/0873—Materials to be treated
    • B01J2219/0892—Materials to be treated involving catalytically active material

Definitions

  • the present invention relates to an apparatus for producing singlet oxygen, and relates particularly, but not exclusively to an assembly for producing singlet oxygen in a flow of air.
  • Singlet oxygen is a reactive energetic form of oxygen which can be formed naturally by the interaction of electromagnetic radiation with atmospheric oxygen. It is desirable to artificially produce large quantities of singlet oxygen for medical and research purposes.
  • photosensitisers which are compounds such as dyes that initiate a photochemical reaction.
  • a photosensitiser is excited by light radiation and subsequent excitonic hits between oxygen molecules and the excited photosensitiser cause the oxygen molecule to become excited to the excited singlet state from the ground triplet stage of oxygen.
  • US6991831 As apparatus for producing singlet oxygen is described in US6991831.
  • This apparatus comprises a plurality of LEDs which are used to emit light radiation.
  • the LEDs and associated electronics are housed in a closed chamber bounded by a transparent glass surface.
  • a substrate on which a photosensitive dye acting as the photosensitiser is applied is disposed beyond the glass screen.
  • Light from the LEDs excites the photosensitive dye causing singlet oxygen to be produced .
  • This apparatus suffers from the drawback that when the LEDs and associated circuitry heat up, unpleasant odours can be produced.
  • the electronics must therefore be located in an enclosed chamber having a transparent screen to allow the light to escape and be projected onto the photosensitive dye. This increases the physical dimensions of the apparatus, which reduces the efficiency of the reaction. This also increases the cost of the apparatus and makes the apparatus more cumbersome to handle.
  • a preferred embodiment of the present invention seeks to overcome the above disadvantages of the prior art.
  • an apparatus for producing singlet oxygen comprising: an activating chamber comprising an inlet for receiving a flow of oxygen and an outlet for exhausting a flow of oxygen containing molecules of singlet oxygen formed in the activating chamber, at least part of an internal wall of the activating chamber being coated with a photosensitiser excitable by absorption of light to excite oxygen to a singlet state; and at least one LED arranged to illuminate the photosensitiser mounted to the internal wall of the activating chamber.
  • Mounting at least one LED internally in the activating chamber provides the advantage of a highly efficient apparatus for producing singlet oxygen that has relatively small physical dimensions. This means that the apparatus can be portable. Even though the LED is mounted internally in the activating chamber, this does not mean that the power supply or control electronics need be present in the activating chamber. This enables an odour free stream of singlet oxygen to be produced.
  • At least part of the internal wall of the activating chamber is formed from a substrate on which at least one surface mount LED arranged to illuminate the photosensitiser is mounted, and wherein control electronics for the at least one surface mount LED are mounted on the opposite surface of the substrate such that the substrate is substantially airtight.
  • the use of at least one surface mount LED arranged to illuminate the photosensitiser is advantageous because this enables the substrate on which the LED is mounted to be air tight. Furthermore, arranging the control electronics on the opposite side of the substrate and using surface mount techniques, rather than through hole techniques to mount the electronics enables the substrate to actually form the wall of the activating chamber without introducing unpleasant odours into the air flow.
  • Using surface mount LEDs enables the LEDs to be located much closer to the photosensitiser, for example within less than lmm, which greatly increases the efficiency of the reaction without causing any unpleasant odours.
  • At least part of the substrate is coated with photosensitiser.
  • Coating the substrate on which the LEDs are mounted with photosensitiser helps to increase the quantity of singlet oxygen produced.
  • a plurality of surface mount LEDs are disposed on the substrate, wherein the substrate surface between the plurality of LEDs is coated with photosensitiser. This further helps to increase the quantity of singlet oxygen produced .
  • the apparatus further comprises first and second activating chambers, wherein a part of the internal walls of each of the first and second activating chambers comprise two surfaces of a carrier, each of the two surfaces being coated with photosensitiser and being arranged in a back-to-back configuration.
  • This provides the advantage of increasing photosensitiser activation and photon reflection from the photosensitising surface to increase the rate of reaction and therefore production of singlet oxygen.
  • the carrier may be at least partially transparent. This provides the advantage of further increasing the rate of reaction.
  • the top and bottom side of each layer of photosensitiser will be illuminated to increase the active surface area.
  • An internal wall coated with photosensitiser may be finely pitted .
  • An internal wall coated with photosensitiser may be formed from polycarbonate, anodised aluminium or glass.
  • At least one LED may be covered by a polycarbonate lens.
  • At least one LED emits a wavelength corresponding to a maximum radiation absorption wavelength of the photosensitiser .
  • At least one LED may be an organic LED (OLED) .
  • organic LEDs can be flat, the overall height of the apparatus can be decreased to increase portability. Furthermore, organic LEDs can also be flexible which means that it is possible for the activation chamber to have many different shapes, for example tubes to be fitted into air conditioning units.
  • the photosensitiser may be a phthalocyanxne.
  • an assembly for producing singlet oxygen comprising: a housing; an apparatus for producing singlet oxygen as defined above mounted in the housing; and a fan mounted in the housing, the fan being adapted to cause air to flow between the inlet and the outlet of the apparatus for producing singlet oxygen.
  • Figure 2 is a perspective view of the apparatus of Figure 1 ;
  • FIG 3 is a perspective view of a housing into which the apparatus of Figures 1 and 2 is mounted.
  • an apparatus 20 for producing singlet oxygen comprises at least one activating chamber 2 comprising an inlet 4 for receiving a flow of oxygen and an outlet 6 for exhausting a flow of oxygen containing molecules of singlet oxygen formed in the activating chamber.
  • At least part of an internal wall of the activating chamber is coated with a photosensitiser 10 excitable by absorption of light to excite oxygen to a singlet state.
  • At least one LED 14 arranged to illuminate the photosensitiser is mounted to the internal wall of the activating chamber.
  • At least part of the internal wall of the activating chamber is formed from a substrate 12 on which at least one surface mount LED 14 arranged to illuminate the photosensitiser is mounted.
  • Control electronics 30 for the at least one surface mount LED 14 are mounted on the opposite surface of the substrate 12 such that the substrate is substantially airtight. All of the electronic components therefore employ chip on board (COB) technology which enables substrate 12 to T B2011/052066
  • a polycarbonate lens may also be cast over the LEDs 14. This helps to prevent any odours from the back of the substrate entering the airstream.
  • apparatus 20 is a LED module having first 2 and second 22 activating chambers which are separated by a carrier 24 having two surfaces 8 and 28 which are arranged in a back-to-back configuration. Each of the surfaces 8 and 28 of the carrier 24 are coated with photosensitiser 10. Photosensitiser 10 is also applied to substrate 12 between the plurality of LEDs 14.
  • the substrate 12 and carrier 24 may be formed from polycarbonate, anodised aluminium or glass and may be finely pitted. Carrier 24 may also be at least partially transparent to enable light emitted by LEDs 14 to impinge on all sides of the photosensitiser 10.
  • the photosensitiser is preferably formed from phthalocyanine .
  • the overall width of module 20 can be made very small, for example 10mm. This means that the light producing LEDs are in very close proximity (from less than 1mm to 5mm) of the photosensitiser 10. Photons can bounce around in the chambers 2 and 22 to excite the photosensitiser and produce singlet oxygen in a flow of air in the direction of arrow A.
  • the use of a photosensitiser excited by light to produce singlet oxygen is a well known process and will not be described in any further detail herein.
  • the at least one LED 14 emits a wavelength corresponding to a maximum radiation absorption wavelength of the phthalocyanine dye photosensitiser. This can be accomplished by using a wavelength between 600 and 700 nanometers .
  • the configuration of the module of Figures 1 and 2 therefore enables a highly portable apparatus 20 to produce a stream of odourless singlet oxygen.
  • the regions between the LEDs can be coated with photosensitiser 10 to further increase the rate of reaction and efficiency of the apparatus. This also helps to reduce the amount of photosensitiser required.
  • organic LEDs can be used. Since organic LEDs can be both flat and flexible, further dimensional reduction is possible and also different shapes of chamber such as a tubular chamber can be accomplished.
  • the photosensitiser 10 is applied in a substantially dust free environment such as a clean room.
  • a predetermined amount of photosensitiser 10 is applied to the substrate 12 or carrier 24, which may be formed from the same material .
  • a layer only a few molecules thick of photosensitiser is applied.
  • the surface to which the photosensitiser is applied is then rotated slightly and put under pressure with microfibers during a brief time of increased temperature. Mechanical fixation of the photosensitiser into the finely pitted surfaces requires a dust free environment to prevent multiple layers of photosensitiser forming. 11 052066
  • housing 40 comprises a fan aperture 42 into which a fan is disposed and a module aperture 44 in which the apparatus 20 of Figures 1 and 2 is disposed.
  • a filter cavity 46 is provided for an air filter and an air inlet 48 enables the fan (not shown) to draw air through the filter and into module 20, and then produce a stream of air through outlet 50 which contains a stream of singlet oxygen molecules .

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Electroluminescent Light Sources (AREA)

Abstract

La présente invention concerne un appareil (20) permettant de produire de l'oxygène singulet. Cet appareil comporte au moins une chambre d'activation (2) comprenant une entrée (4) destinée à recevoir un courant d'oxygène et une sortie (6) destinée à évacuer un courant d'oxygène contenant des molécules d'oxygène singulet formées dans la chambre d'activation. Au moins une partie d'une paroi intérieure de la chambre d'activation est revêtue d'un photosensibilisateur (10) excitable par absorption de lumière pour exciter l'oxygène et le faire passer à un état singulet. Au moins une DEL (14) conçue pour éclairer le photosensibilisateur est montée sur la paroi intérieure de la chambre d'activation.
PCT/GB2011/052066 2010-10-28 2011-10-25 Appareil permettant de produire de l'oxygène singulet WO2012056225A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1018204.6A GB201018204D0 (en) 2010-10-28 2010-10-28 Apparatus for producing singlet oxygen
GB1018204.6 2010-10-28

Publications (1)

Publication Number Publication Date
WO2012056225A1 true WO2012056225A1 (fr) 2012-05-03

Family

ID=43401437

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2011/052066 WO2012056225A1 (fr) 2010-10-28 2011-10-25 Appareil permettant de produire de l'oxygène singulet

Country Status (2)

Country Link
GB (1) GB201018204D0 (fr)
WO (1) WO2012056225A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013220210A1 (de) 2013-10-07 2015-04-09 Lr Health & Beauty Systems Gmbh Vorrichtung und Verfahren zur Erzeugung von Singulett-Sauerstoff
WO2016079726A1 (fr) 2014-11-20 2016-05-26 Z5 Global Group Limited Production d'oxydants
WO2016113535A1 (fr) 2015-01-13 2016-07-21 Soe Health Limited Méthodes de traitement thérapeutique et appareil destiné à être utilisé au cours de celles-ci
CN112062094A (zh) * 2020-09-03 2020-12-11 自然空气能量解决方案有限公司 一种单线态氧制备装置及单线态氧制备方法
WO2021041430A1 (fr) * 2019-08-28 2021-03-04 Portland State University Système et procédé faisant appel au stockage et à la libération photochimique d'oxygène
US20220211894A1 (en) * 2020-11-12 2022-07-07 California Institute Of Technology Photocatalytic generation of singlet oxygen for air purification

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991831B2 (en) 2000-09-28 2006-01-31 Natural Energy Solutions, Ag Method and device for producing singlet oxygen
EP1852391A1 (fr) * 2006-05-02 2007-11-07 Medical Biophysics GmbH Dispositif et procédé de génération d'un fluide activé par l'oxygène singulet
WO2009030477A1 (fr) * 2007-09-07 2009-03-12 Valkion Ab Dispositif de production d'un oxygène singulet par irradiation d'une matière sensible à la lumière
DE102010017892A1 (de) * 2010-04-21 2011-10-27 Kirsten Klemm Verfahren und Vorrichtung zur Sauerstoff-Anregung vom Triplett- zum Singulett-Zustand

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6991831B2 (en) 2000-09-28 2006-01-31 Natural Energy Solutions, Ag Method and device for producing singlet oxygen
EP1852391A1 (fr) * 2006-05-02 2007-11-07 Medical Biophysics GmbH Dispositif et procédé de génération d'un fluide activé par l'oxygène singulet
WO2009030477A1 (fr) * 2007-09-07 2009-03-12 Valkion Ab Dispositif de production d'un oxygène singulet par irradiation d'une matière sensible à la lumière
DE102010017892A1 (de) * 2010-04-21 2011-10-27 Kirsten Klemm Verfahren und Vorrichtung zur Sauerstoff-Anregung vom Triplett- zum Singulett-Zustand

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013220210A1 (de) 2013-10-07 2015-04-09 Lr Health & Beauty Systems Gmbh Vorrichtung und Verfahren zur Erzeugung von Singulett-Sauerstoff
EP3221259A4 (fr) * 2014-11-20 2018-08-01 Z5 Global Group Limited Production d'oxydants
WO2016079726A1 (fr) 2014-11-20 2016-05-26 Z5 Global Group Limited Production d'oxydants
US11007129B2 (en) 2014-11-20 2021-05-18 Z5 Global Group Limited Oxidant production
GB2539742B (en) * 2015-01-13 2019-05-22 Soe Health Ltd Therapeutic treatment methods, and apparatus for use therein
US20180021531A1 (en) * 2015-01-13 2018-01-25 Soe Health Limited Therapeutic Treatment Methods and Apparatus for Use Therein
GB2539742A (en) * 2015-01-13 2016-12-28 Soe Health Ltd Therapeutic treatment methods, and apparatus for use therein
US10632270B2 (en) 2015-01-13 2020-04-28 Soe Health Limited Therapeutic treatment methods and apparatus for use therein
WO2016113535A1 (fr) 2015-01-13 2016-07-21 Soe Health Limited Méthodes de traitement thérapeutique et appareil destiné à être utilisé au cours de celles-ci
WO2021041430A1 (fr) * 2019-08-28 2021-03-04 Portland State University Système et procédé faisant appel au stockage et à la libération photochimique d'oxygène
CN114340676A (zh) * 2019-08-28 2022-04-12 波特兰州立大学 利用光化学储存和释放氧的系统和方法
CN114340676B (zh) * 2019-08-28 2024-03-22 波特兰州立大学 利用光化学储存和释放氧的系统和方法
CN112062094A (zh) * 2020-09-03 2020-12-11 自然空气能量解决方案有限公司 一种单线态氧制备装置及单线态氧制备方法
US20220211894A1 (en) * 2020-11-12 2022-07-07 California Institute Of Technology Photocatalytic generation of singlet oxygen for air purification

Also Published As

Publication number Publication date
GB201018204D0 (en) 2010-12-15

Similar Documents

Publication Publication Date Title
WO2012056225A1 (fr) Appareil permettant de produire de l'oxygène singulet
US10632216B2 (en) Multifunction light-emitting diode lighting apparatus
US8579476B2 (en) Thermal management of led-based illumination devices with synthetic jet ejectors
US8777456B2 (en) Thermal management of LED-based illumination devices with synthetic jet ejectors
CN1167924C (zh) 冷冻冷藏冰箱
RU2010108010A (ru) Способ очистки окружающего воздуха и поверхностей и устройство для его осуществления
US20070024814A1 (en) Image projecting apparatus
KR20170114678A (ko) 공기 정화 기능을 내장한 엘이디 조명기기
KR20150112755A (ko) Uv led 램프를 사용한 포충기
KR101101137B1 (ko) 팬 장착 제균 조명장치
KR20170131250A (ko) 포충기
WO2009104119A2 (fr) Système de désinfection, fabrication et utilisation
WO2017158943A1 (fr) Dispositif de formation de motif et procédé de fabrication d'élément électroluminescent organique
RU115662U1 (ru) Устройство для обеззараживания воздуха
JP5023436B2 (ja) 紫外線照射装置
ES2277008T3 (es) Dispositivo para endurecer revestimientos endurecibles por radiacion uv.
KR101231695B1 (ko) 이온발생장치를 구비한 엘이디 램프
WO2016175274A1 (fr) Module de photocatalyseur et réfrigérateur le comprenant
KR200367905Y1 (ko) 엑시머 램프
CN206786374U (zh) 一种单排水冷紫外光源
CN213000999U (zh) 一种led-uv固化机
US20140268791A1 (en) Lighting fixtures for solid-state light sources
EP2192976A1 (fr) Dispositif de production d'un oxygène singulet par irradiation d'une matière sensible à la lumière
CN218268896U (zh) 可进行空气消杀的照明结构及具有其的灯具
TW201413169A (zh) 光觸媒照明燈具

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11779199

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11779199

Country of ref document: EP

Kind code of ref document: A1