WO2012053832A3 - 4-o-메틸호노키올의 합성방법 - Google Patents
4-o-메틸호노키올의 합성방법 Download PDFInfo
- Publication number
- WO2012053832A3 WO2012053832A3 PCT/KR2011/007819 KR2011007819W WO2012053832A3 WO 2012053832 A3 WO2012053832 A3 WO 2012053832A3 KR 2011007819 W KR2011007819 W KR 2011007819W WO 2012053832 A3 WO2012053832 A3 WO 2012053832A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methylhonokiol
- synthesising
- present
- purity
- extraction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
- C07C37/18—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by condensation involving halogen atoms of halogenated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
본 발명은 유용한 활성화합물인 4-O-메틸호노키올을 화학적인 방법으로 합성하는 제법에 관한 것이다. 본 발명에 의하면 종래의 천연물로부터 추출하여 4-O-메틸호노키올을 얻는 방법에 비해 월등히 높은 수율로 고순도의 4-O-메틸호노키올을 대량 생산할 수 있는 장점이 있다.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2010-0102491 | 2010-10-20 | ||
KR1020100102491A KR101492225B1 (ko) | 2010-10-20 | 2010-10-20 | 4-o-메틸호노키올의 합성방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012053832A2 WO2012053832A2 (ko) | 2012-04-26 |
WO2012053832A3 true WO2012053832A3 (ko) | 2012-06-21 |
Family
ID=45975738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2011/007819 WO2012053832A2 (ko) | 2010-10-20 | 2011-10-20 | 4-o-메틸호노키올의 합성방법 |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR101492225B1 (ko) |
WO (1) | WO2012053832A2 (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103664431B (zh) * | 2013-12-06 | 2016-11-16 | 德州学院 | 一种芳基-芳基联苯类化合物的制备方法 |
CN103664747A (zh) * | 2013-12-06 | 2014-03-26 | 刘雷芳 | 一种杂环联苯类化合物的制备方法 |
CN114907228B (zh) * | 2022-06-27 | 2023-11-28 | 深圳市锦泰医药科技合伙企业(有限合伙) | 一种秋水仙碱和厚朴酚复合物及其合成方法以及在抗新冠病毒方面的应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5053548A (en) * | 1989-02-08 | 1991-10-01 | Otsuka Pharmaceutical Company, Ltd. | Biphenyl derivative composition for nerve cell degeneration repairing or protective agent and process for preparing a phenyl derivative contained in the composition |
-
2010
- 2010-10-20 KR KR1020100102491A patent/KR101492225B1/ko active IP Right Grant
-
2011
- 2011-10-20 WO PCT/KR2011/007819 patent/WO2012053832A2/ko active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5053548A (en) * | 1989-02-08 | 1991-10-01 | Otsuka Pharmaceutical Company, Ltd. | Biphenyl derivative composition for nerve cell degeneration repairing or protective agent and process for preparing a phenyl derivative contained in the composition |
Non-Patent Citations (4)
Also Published As
Publication number | Publication date |
---|---|
WO2012053832A2 (ko) | 2012-04-26 |
KR101492225B1 (ko) | 2015-03-09 |
KR20120040959A (ko) | 2012-04-30 |
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