WO2011037976A3 - Formulations pharmaceutiques de pramipexole - Google Patents

Formulations pharmaceutiques de pramipexole Download PDF

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Publication number
WO2011037976A3
WO2011037976A3 PCT/US2010/049785 US2010049785W WO2011037976A3 WO 2011037976 A3 WO2011037976 A3 WO 2011037976A3 US 2010049785 W US2010049785 W US 2010049785W WO 2011037976 A3 WO2011037976 A3 WO 2011037976A3
Authority
WO
WIPO (PCT)
Prior art keywords
pramipexole
pharmaceutical formulations
manufacturing
methods
pharmaceutically acceptable
Prior art date
Application number
PCT/US2010/049785
Other languages
English (en)
Other versions
WO2011037976A2 (fr
Inventor
Snehalatha Movva
Hemanth Prakash Joshi
Pramod Kharwade
Badri Vishwanathan Narayanan
Prashanth Reddy Molugu
Prasad Vure
Ajmal Shareef Md
Nageswara Rao Vysyaraju
Prem Prakash Singh
Bhushan Subhash Yeola
Harshal Prabhakar Bhagwatwar
Original Assignee
Dr. Reddy's Laboratories Limited
Dr. Reddy's Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc. filed Critical Dr. Reddy's Laboratories Limited
Publication of WO2011037976A2 publication Critical patent/WO2011037976A2/fr
Publication of WO2011037976A3 publication Critical patent/WO2011037976A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Dans certains aspects, la présente invention concerne des formulations pharmaceutiques qui comprennent du pramipexole ou des sels pharmaceutiquement acceptables de celui-ci, des procédés de fabrication associés, et leurs utilisations. Dans d'autres aspects, la présente invention concerne des formulations stables à libération prolongées destinées à une administration par voie orale, qui comprennent du pramipexole ou des sels pharmaceutiquement acceptables de celui-ci et de la cellulose microcristalline, des procédés de fabrication associés, et leurs utilisations.
PCT/US2010/049785 2009-09-22 2010-09-22 Formulations pharmaceutiques de pramipexole WO2011037976A2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN2286CH2009 2009-09-22
IN2286/CHE/2009 2009-09-22
US31153410P 2010-03-08 2010-03-08
US61/311,534 2010-03-08
IN2570/CHE/2010 2010-09-03
IN2570CH2010 2010-09-03

Publications (2)

Publication Number Publication Date
WO2011037976A2 WO2011037976A2 (fr) 2011-03-31
WO2011037976A3 true WO2011037976A3 (fr) 2011-08-25

Family

ID=43796460

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/049785 WO2011037976A2 (fr) 2009-09-22 2010-09-22 Formulations pharmaceutiques de pramipexole

Country Status (1)

Country Link
WO (1) WO2011037976A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130209553A1 (en) * 2010-04-15 2013-08-15 Cadila Healthcare Limited Extended release pharmaceutical compositions of pramipexole
KR101307334B1 (ko) * 2010-07-02 2013-09-12 주식회사 바이오파마티스 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물
WO2013034173A1 (fr) * 2011-09-06 2013-03-14 Synthon Bv Comprimés à libération prolongée de pramipexole
EP2732812A1 (fr) 2012-11-15 2014-05-21 Aristo Pharma GmbH Comprimé de pramipexol à libération prolongée
CN103040781B (zh) * 2013-01-04 2014-07-16 杭州朱养心药业有限公司 盐酸普拉克索片剂药物组合物及其制备方法
AU2015295846B2 (en) 2014-07-30 2020-07-09 Merck Patent Gmbh Directly compressible composition containing micro-crystalline cellulose
CN105796519A (zh) * 2014-12-30 2016-07-27 浙江京新药业股份有限公司 盐酸普拉克索缓释片及其制备方法
CN106983729B (zh) * 2016-01-21 2021-02-26 北京北大维信生物科技有限公司 普拉克索缓释片及制备方法
CN109966256B (zh) * 2017-12-28 2022-08-02 北京北大维信生物科技有限公司 一种普拉克索缓释药物组合物、其制备方法及用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010999A1 (fr) * 2002-07-25 2004-02-05 Pharmacia Corporation Forme posologique a prise unique quotidienne de pramipexole
US20050226926A1 (en) * 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
WO2006046256A1 (fr) * 2004-10-27 2006-05-04 Alembic Limited Formulation a liberation prolongee de dihydrochlorure de pramipexole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010999A1 (fr) * 2002-07-25 2004-02-05 Pharmacia Corporation Forme posologique a prise unique quotidienne de pramipexole
US20050226926A1 (en) * 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
WO2006046256A1 (fr) * 2004-10-27 2006-05-04 Alembic Limited Formulation a liberation prolongee de dihydrochlorure de pramipexole

Also Published As

Publication number Publication date
WO2011037976A2 (fr) 2011-03-31

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