WO2011014855A3 - Désoxygénation de fluides biologiques - Google Patents

Désoxygénation de fluides biologiques Download PDF

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Publication number
WO2011014855A3
WO2011014855A3 PCT/US2010/044045 US2010044045W WO2011014855A3 WO 2011014855 A3 WO2011014855 A3 WO 2011014855A3 US 2010044045 W US2010044045 W US 2010044045W WO 2011014855 A3 WO2011014855 A3 WO 2011014855A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxygen
tubes
removal
biological fluids
concentration
Prior art date
Application number
PCT/US2010/044045
Other languages
English (en)
Other versions
WO2011014855A2 (fr
Inventor
William J. Federspiel
Tatsuro Yoshida
Paul J. Vernucci
Brian Joseph Frankowski
Laura Wheeler Lund
Original Assignee
University Of Pittsburgh -Of The Commonwealth System Of Higher Education
New Health Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Pittsburgh -Of The Commonwealth System Of Higher Education, New Health Sciences, Inc. filed Critical University Of Pittsburgh -Of The Commonwealth System Of Higher Education
Priority to CA2772320A priority Critical patent/CA2772320A1/fr
Priority to US13/387,528 priority patent/US20120129149A1/en
Priority to NZ598410A priority patent/NZ598410A/en
Priority to JP2012523121A priority patent/JP5770183B2/ja
Priority to AU2010278768A priority patent/AU2010278768A1/en
Priority to EP10805155.8A priority patent/EP2459247A4/fr
Publication of WO2011014855A2 publication Critical patent/WO2011014855A2/fr
Publication of WO2011014855A3 publication Critical patent/WO2011014855A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/022—Encapsulating hollow fibres
    • B01D63/0221—Encapsulating hollow fibres using a mould
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1627—Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/13—Use of sweep gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2626—Absorption or adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/40—Adsorbents within the flow path

Abstract

L'invention concerne un système de réduction de la concentration d'oxygène dans un fluide comportant des globules rouges comprenant un boîtier, une pluralité de tubes creux s'étendant à l'intérieur du boîtier et conçus pour que le fluide les traverse en s'écoulant, chaque tube comportant une entrée et une sortie, et un système vecteur réduisant la concentration d'oxygène sur une surface extérieure des tubes pour faciliter le transport d'oxygène du fluide s'écoulant à travers les tubes vers l'extérieur des tubes.
PCT/US2010/044045 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques WO2011014855A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA2772320A CA2772320A1 (fr) 2009-07-31 2010-07-31 Desoxygenation de fluides biologiques
US13/387,528 US20120129149A1 (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids
NZ598410A NZ598410A (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids
JP2012523121A JP5770183B2 (ja) 2009-07-31 2010-07-31 生体液からの酸素除去
AU2010278768A AU2010278768A1 (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids
EP10805155.8A EP2459247A4 (fr) 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23057509P 2009-07-31 2009-07-31
US61/230,575 2009-07-31

Publications (2)

Publication Number Publication Date
WO2011014855A2 WO2011014855A2 (fr) 2011-02-03
WO2011014855A3 true WO2011014855A3 (fr) 2011-06-16

Family

ID=43529974

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/044045 WO2011014855A2 (fr) 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques

Country Status (7)

Country Link
US (1) US20120129149A1 (fr)
EP (1) EP2459247A4 (fr)
JP (1) JP5770183B2 (fr)
AU (1) AU2010278768A1 (fr)
CA (1) CA2772320A1 (fr)
NZ (1) NZ598410A (fr)
WO (1) WO2011014855A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
BR112012008683B8 (pt) 2009-10-12 2022-11-08 Hemanext Inc dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias
WO2011046963A1 (fr) 2009-10-12 2011-04-21 New Health Sciences, Inc. Dispositifs d'appauvrissement en oxygène et procédés pour retirer l'oxygène de globules rouges
WO2012027582A1 (fr) 2010-08-25 2012-03-01 New Health Sciences Procédé pour augmenter la qualité et la survie pendant la conservation d'érythrocytes
PT2635114T (pt) 2010-11-05 2020-06-16 New Health Sciences Inc Irradiação de glóbulos vermelhos e armazenamento anaeróbico
JP2014510731A (ja) 2011-03-16 2014-05-01 メイヨー ファンデーション フォー メディカル エデュケーション アンド リサーチ 赤血球製剤および血小板製剤の有効貯蔵を延ばすための方法および材料
US9067004B2 (en) * 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
CN103492041B (zh) * 2011-03-28 2017-02-08 新健康科学股份有限公司 用于在红细胞血液处理过程中使用惰性载气和歧管组件去除氧和二氧化碳的方法和系统
DE102011052187A1 (de) * 2011-07-27 2013-01-31 Maquet Vertrieb Und Service Deutschland Gmbh Anordnung zum Entfernen von Kohlenstoffdioxid aus einem exkorporalen Blutstrom mittels Inertgasen
ES2923571T3 (es) 2011-08-10 2022-09-28 Hemanext Inc Dispositivo integrado de filtrado de leucocitos, oxígeno y/o CO2 y separación de plasma
GB201207543D0 (en) * 2012-05-01 2012-06-13 Haemair Ltd Treatment of transfusion blood
AU2014223165B2 (en) * 2013-02-28 2017-04-13 Hemanext Inc. Gas depletion and gas addition devices for blood treatment
KR20180012242A (ko) 2015-03-10 2018-02-05 뉴 헬스 사이언시즈 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
IL285359B2 (en) 2015-04-23 2024-01-01 Hemanext Inc Anaerobic blood storage containers
CA2985799A1 (fr) 2015-05-18 2016-11-24 New Health Sciences, Inc. Procedes pour le stockage de sang total et compositions correspondantes
EP3463466B1 (fr) 2016-05-27 2022-02-16 Hemanext Inc. Stockage de sang anaérobie et procédé d'inactivation de pathogènes

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US4749551A (en) * 1985-09-24 1988-06-07 Sorin Biomedica S.P.A. Hollow-fiber oxygenators for blood
US5192320A (en) * 1987-07-11 1993-03-09 Dainippon Ink And Chemicals Inc. Artificial lung and method of using it
US6162396A (en) * 1997-04-26 2000-12-19 The Regents Of The University Of California Blood storage device and method for oxygen removal
WO2006057473A1 (fr) * 2004-11-23 2006-06-01 Newheart Bio Co., Ltd. Module de filtre muni de parties multifonctionnelles correspondantes avec purification et/ou oxygenation de sang et procede de purification de sang ainsi que dispositif de purification et d'oxygenation de sang comprenant ce module

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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US4749551A (en) * 1985-09-24 1988-06-07 Sorin Biomedica S.P.A. Hollow-fiber oxygenators for blood
US5192320A (en) * 1987-07-11 1993-03-09 Dainippon Ink And Chemicals Inc. Artificial lung and method of using it
US6162396A (en) * 1997-04-26 2000-12-19 The Regents Of The University Of California Blood storage device and method for oxygen removal
WO2006057473A1 (fr) * 2004-11-23 2006-06-01 Newheart Bio Co., Ltd. Module de filtre muni de parties multifonctionnelles correspondantes avec purification et/ou oxygenation de sang et procede de purification de sang ainsi que dispositif de purification et d'oxygenation de sang comprenant ce module

Also Published As

Publication number Publication date
JP5770183B2 (ja) 2015-08-26
NZ598410A (en) 2014-04-30
WO2011014855A2 (fr) 2011-02-03
AU2010278768A1 (en) 2012-03-15
JP2013500794A (ja) 2013-01-10
US20120129149A1 (en) 2012-05-24
EP2459247A4 (fr) 2013-08-28
CA2772320A1 (fr) 2011-02-03
EP2459247A2 (fr) 2012-06-06

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