WO2011014025A3 - Dérivé d'acide hydroxycinnamique comprenant une liaison peptidique, son procédé de production, et composition cosmétique comprenant le dérivé - Google Patents

Dérivé d'acide hydroxycinnamique comprenant une liaison peptidique, son procédé de production, et composition cosmétique comprenant le dérivé Download PDF

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Publication number
WO2011014025A3
WO2011014025A3 PCT/KR2010/004999 KR2010004999W WO2011014025A3 WO 2011014025 A3 WO2011014025 A3 WO 2011014025A3 KR 2010004999 W KR2010004999 W KR 2010004999W WO 2011014025 A3 WO2011014025 A3 WO 2011014025A3
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WO
WIPO (PCT)
Prior art keywords
same
peptide
hydroxy
derivative
bonded
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PCT/KR2010/004999
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English (en)
Korean (ko)
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WO2011014025A2 (fr
Inventor
이윤식
곽선영
서효석
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서울대학교 산학협력단
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Publication of WO2011014025A2 publication Critical patent/WO2011014025A2/fr
Publication of WO2011014025A3 publication Critical patent/WO2011014025A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un dérivé d'acide hydroxycinnamique comprenant une liaison peptidique, son procédé de production, et une composition cosmétique comprenant le dérivé. Elle concerne plus particulièrement un dérivé d'acide hydroxycinnamique dans lequel est lié un peptide présentant un effet antioxydant; un procédé de production du dérivé; et une composition cosmétique pour le blanchiment de la peau et la prévention de la vieillesse qui comprend le dérivé et présente ainsi un effet antioxydant accru et sans toxicité pour les cellules.
PCT/KR2010/004999 2009-07-30 2010-07-29 Dérivé d'acide hydroxycinnamique comprenant une liaison peptidique, son procédé de production, et composition cosmétique comprenant le dérivé WO2011014025A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090069734A KR20110012148A (ko) 2009-07-30 2009-07-30 펩타이드가 결합된 하이드록시 시나믹산 유도체, 이의 제조 방법 및 이를 포함하는 화장품 조성물
KR10-2009-0069734 2009-07-30

Publications (2)

Publication Number Publication Date
WO2011014025A2 WO2011014025A2 (fr) 2011-02-03
WO2011014025A3 true WO2011014025A3 (fr) 2011-06-30

Family

ID=43529886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/004999 WO2011014025A2 (fr) 2009-07-30 2010-07-29 Dérivé d'acide hydroxycinnamique comprenant une liaison peptidique, son procédé de production, et composition cosmétique comprenant le dérivé

Country Status (2)

Country Link
KR (1) KR20110012148A (fr)
WO (1) WO2011014025A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9688722B2 (en) 2012-05-04 2017-06-27 The Board Of Regents Of The University Of Oklahoma Substrates and inhibitors of prolyl oligopeptidase and methods of use
KR101710486B1 (ko) * 2015-01-05 2017-02-28 주식회사 앤코스메슈 올리고펩타이드 유도체 및 이를 포함하는 주름개선용 조성물
KR101705338B1 (ko) * 2015-10-26 2017-02-09 주식회사 인코스팜 항산화, 항노화 및 자가포식 활성을 가지는 조성물 및 이의 용도
KR102101339B1 (ko) * 2017-03-29 2020-04-16 주식회사 비드테크 피부질환 예방 또는 치료용 조성물 및 제조방법
US10695279B2 (en) 2017-04-27 2020-06-30 Caregen Co., Ltd. Peptide having skin-whitening activity and use thereof
KR101970465B1 (ko) * 2017-06-09 2019-04-22 주식회사 바이오에프디엔씨 누에 유래 펩타이드 및 카페익산이 결합된 신규한 펩타이드 유도체의 용도
KR102124912B1 (ko) * 2018-05-24 2020-06-19 원광대학교 산학협력단 신규한 올리고펩타이드 유도체 및 이의 용도
KR101958207B1 (ko) * 2018-09-13 2019-03-14 (주)케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR102404228B1 (ko) * 2022-02-18 2022-05-31 주식회사 차메디텍 항산화 효과를 증대시키는 환원된 리포익산-펩타이드 유도체를 포함하는 조성물 및 이의 제조 방법
CN115581633B (zh) * 2022-10-14 2023-09-12 深圳市维琪科技股份有限公司 肽类化合物在制备用于皮肤延衰修复的组合物中的新用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276204A (en) * 1940-01-02 1942-03-10 Kilgore Dev Corp Chemical light filter
DE2728242A1 (de) * 1977-06-23 1979-01-11 Henkel Kgaa Kosmetische lichtschutzmittel fuer den uv-a-bereich
US6121243A (en) * 1994-12-13 2000-09-19 Beiersdorf Ag Treatment of skin with a formulation comprising alpha-glucosyl rutin and one or more cinnamic acid derivatives
US20080152603A1 (en) * 2005-04-19 2008-06-26 Thomas Rudolph Antioxidants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276204A (en) * 1940-01-02 1942-03-10 Kilgore Dev Corp Chemical light filter
DE2728242A1 (de) * 1977-06-23 1979-01-11 Henkel Kgaa Kosmetische lichtschutzmittel fuer den uv-a-bereich
US6121243A (en) * 1994-12-13 2000-09-19 Beiersdorf Ag Treatment of skin with a formulation comprising alpha-glucosyl rutin and one or more cinnamic acid derivatives
US20080152603A1 (en) * 2005-04-19 2008-06-26 Thomas Rudolph Antioxidants

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Publication number Publication date
WO2011014025A2 (fr) 2011-02-03
KR20110012148A (ko) 2011-02-09

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