WO2011002323A3 - Procédé pour la production directe de 99mtc (technétium 99 métastable) à partir d'accélérateurs à basse énergie - Google Patents

Procédé pour la production directe de 99mtc (technétium 99 métastable) à partir d'accélérateurs à basse énergie Download PDF

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Publication number
WO2011002323A3
WO2011002323A3 PCT/PT2010/000026 PT2010000026W WO2011002323A3 WO 2011002323 A3 WO2011002323 A3 WO 2011002323A3 PT 2010000026 W PT2010000026 W PT 2010000026W WO 2011002323 A3 WO2011002323 A3 WO 2011002323A3
Authority
WO
WIPO (PCT)
Prior art keywords
99mtc
target
protons
direct production
technetium
Prior art date
Application number
PCT/PT2010/000026
Other languages
English (en)
Other versions
WO2011002323A2 (fr
Inventor
Richard Ray Johnson
Luís Francisco De Oliveira Marques METELLO
Lídia Alexandra Dos Santos CUNHA
Vesna Sossi
Original Assignee
Isopor - Isótopos Para Diagnóstico E Terapêutica, S.A.
Best Cyclotron System, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT10465609A external-priority patent/PT104656A/pt
Application filed by Isopor - Isótopos Para Diagnóstico E Terapêutica, S.A., Best Cyclotron System, Inc. filed Critical Isopor - Isótopos Para Diagnóstico E Terapêutica, S.A.
Publication of WO2011002323A2 publication Critical patent/WO2011002323A2/fr
Publication of WO2011002323A3 publication Critical patent/WO2011002323A3/fr

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Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001—Recovery of specific isotopes from irradiated targets
    • G21G2001/0042—Technetium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Particle Accelerators (AREA)
  • Liquid Crystal (AREA)
  • Looms (AREA)

Abstract

L'invention concerne une cible, un logiciel informatique et un procédé pour la production directe de 99mTc au moyen d'accélérateurs à basse énergie. Le procédé consiste à positionner un support de cible à bombarder par un faisceau de protons, le support de cible présentant une cible qui possède une première couche centrale rigide, une deuxième couche centrale rigide, une troisième couche à haute teneur en 100Mo et un substrat, agencés dans cet ordre; à bombarder la cible avec le faisceau de protons, les protons présentant une énergie comprise entre 10 et 35 MeV et un courant compris entre 20 et 500 µA; et à achever le bombardement par le faisceau de protons après un intervalle temporel compris entre une demi-heure et huit heures.
PCT/PT2010/000026 2009-07-01 2010-06-30 Procédé pour la production directe de 99mtc (technétium 99 métastable) à partir d'accélérateurs à basse énergie WO2011002323A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PT104656 2009-07-01
PT10465609A PT104656A (pt) 2009-07-01 2009-07-01 Processo de produção de tecnécio-99 metaestável em ciclotrões de baixa energia e alvo de molibdnénio-100 utilizado no processo
US12/512,529 2009-07-30
US12/512,529 US20110002431A1 (en) 2009-07-01 2009-07-30 METHOD FOR DIRECT PRODUCTION OF 99mTc - TECHNETIUM 99 METASTABLE FROM LOW ENERGY ACCELERATORS

Publications (2)

Publication Number Publication Date
WO2011002323A2 WO2011002323A2 (fr) 2011-01-06
WO2011002323A3 true WO2011002323A3 (fr) 2011-04-07

Family

ID=42668084

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PT2010/000026 WO2011002323A2 (fr) 2009-07-01 2010-06-30 Procédé pour la production directe de 99mtc (technétium 99 métastable) à partir d'accélérateurs à basse énergie

Country Status (1)

Country Link
WO (1) WO2011002323A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9587292B2 (en) * 2009-10-01 2017-03-07 Advanced Applied Physics Solutions, Inc. Method and apparatus for isolating the radioisotope molybdenum-99
WO2018225761A1 (fr) * 2017-06-09 2018-12-13 株式会社カネカ Cible de rayonnement de faisceau de protons ou de faisceau de neutrons et procédé de génération d'une substance radioactive à l'aide de celle-ci
IT201800004594A1 (it) * 2018-04-17 2019-10-17 Processo per la realizzazione di target per la produzione di radioisotopi

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874811A (en) * 1994-08-19 1999-02-23 Nycomed Amersham Plc Superconducting cyclotron for use in the production of heavy isotopes
DE10028056A1 (de) * 2000-06-06 2002-01-10 Frank Roesch Radionuklidgenerator und Verfahren zur Abtrennung von trägerfreiem 72As

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874811A (en) * 1994-08-19 1999-02-23 Nycomed Amersham Plc Superconducting cyclotron for use in the production of heavy isotopes
DE10028056A1 (de) * 2000-06-06 2002-01-10 Frank Roesch Radionuklidgenerator und Verfahren zur Abtrennung von trägerfreiem 72As

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERNHARD SCHOLTEN, RICHARD M. LAMBRECHT, MICHEL COGNEAU, HERNAN VERA RUIZ AND SYED M. QAIM: "Excitation functions for the cyclotron production of 99mTc and 99Mo", APPLIED RADIATION AND ISOTOPES, vol. 51, no. 1, July 1999 (1999-07-01), pages 69 - 80, XP002599950, ISSN: 0969-8043 *
EGAN G ET AL: "An Investigation Into the Technical Feasibility of Cyclotron Production of Technetium-99m", 1 March 1994, ANZ NUCLEAR MEDICINE, LLE, PAGE(S) 25 - 31, ISSN: 1324-1435, XP001525420 *
TAKÁCS ET AL.: "Evaluation of proton induced reactions on 100Mo: New cross sections for production of 99mTc and 99Mo", JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, vol. 257, no. 1, July 2003 (2003-07-01), pages 195 - 201, XP002599949, ISSN: 0236-5731 *

Also Published As

Publication number Publication date
WO2011002323A2 (fr) 2011-01-06

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