WO2010142007A8 - Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais - Google Patents

Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais Download PDF

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Publication number
WO2010142007A8
WO2010142007A8 PCT/BR2009/000375 BR2009000375W WO2010142007A8 WO 2010142007 A8 WO2010142007 A8 WO 2010142007A8 BR 2009000375 W BR2009000375 W BR 2009000375W WO 2010142007 A8 WO2010142007 A8 WO 2010142007A8
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
prophylaxis
humans
animals
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BR2009/000375
Other languages
English (en)
French (fr)
Other versions
WO2010142007A1 (pt
Inventor
José Agustín QUINCOCES SUÁREZ
Durvanei Augusto Maria
Paulo Celso Pardi
Fernanda FAIÃO FLORES
Reginaldo Pereira Santos
Daniela GONÇALES RANDO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Academia Paulista Ancheta SC Ltda Universidade Bandeirante de Sao Paulo
Original Assignee
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Academia Paulista Ancheta SC Ltda Universidade Bandeirante de Sao Paulo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP, Academia Paulista Ancheta SC Ltda Universidade Bandeirante de Sao Paulo filed Critical Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Priority to EP09845661.9A priority Critical patent/EP2441452B1/en
Priority to JP2012514299A priority patent/JP5802658B2/ja
Priority to US13/377,194 priority patent/US9381169B2/en
Publication of WO2010142007A1 publication Critical patent/WO2010142007A1/pt
Anticipated expiration legal-status Critical
Publication of WO2010142007A8 publication Critical patent/WO2010142007A8/pt
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

A presente invenção refere-se a composições farmacêuticas que compreendem fenolatos metálicos polifuncionais que apresentam aplicações biológicas como adjuvantes antitumorais, citoprotetores, agentes antimetastáticos e agentes antimutagênicos quando associados a quimioterápicos. A presente invenção refere-se ainda ao uso fenolatos metálicos polifuncionais na preparação de medicamentos para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais.
PCT/BR2009/000375 2009-06-09 2009-11-11 Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais Ceased WO2010142007A1 (pt)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP09845661.9A EP2441452B1 (en) 2009-06-09 2009-11-11 Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals
JP2012514299A JP5802658B2 (ja) 2009-06-09 2009-11-11 人および動物の腫瘍性疾患の治療、抑制あるいは予防用医薬組成物、および医薬組成物の使用
US13/377,194 US9381169B2 (en) 2009-06-09 2009-11-11 Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0902039-0 2009-06-09
BRPI0902039A BRPI0902039B8 (pt) 2009-06-09 2009-06-09 composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais

Publications (2)

Publication Number Publication Date
WO2010142007A1 WO2010142007A1 (pt) 2010-12-16
WO2010142007A8 true WO2010142007A8 (pt) 2012-01-26

Family

ID=43308327

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2009/000375 Ceased WO2010142007A1 (pt) 2009-06-09 2009-11-11 Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais

Country Status (5)

Country Link
US (1) US9381169B2 (pt)
EP (1) EP2441452B1 (pt)
JP (1) JP5802658B2 (pt)
BR (1) BRPI0902039B8 (pt)
WO (1) WO2010142007A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115414465B (zh) * 2022-10-17 2025-01-10 苏州明人医药生物科技有限公司 Jwa多肽在制备抗肿瘤药协同增效剂方面的应用
CN120585875B (zh) * 2025-07-03 2026-02-06 河北医科大学第四医院（河北省肿瘤医院） 一种治疗耐药性卵巢癌的水凝胶微球及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4883666A (en) 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
DE3829752A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
DE3829766A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Verfahren zur herstellung von membranen
US5082670A (en) 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5618531A (en) 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
SG47470A1 (en) 1991-04-25 1998-04-17 Univ Brown Res Found Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products
US5854217A (en) 1992-09-28 1998-12-29 Bearsden Bio, Inc. Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function
SG48813A1 (en) 1993-08-12 1998-05-18 Cytotherapeutics Inc Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
EP1242379A1 (en) 1999-12-03 2002-09-25 Emory University Curcumin analogues for treating cancer
US7355081B2 (en) * 2002-04-17 2008-04-08 The University Of North Carolina At Chapel Hill Curcumin analogues and uses thereof
US8841326B2 (en) * 2004-02-12 2014-09-23 Stc.Unm Therapeutic curcumin derivatives
US20060258752A1 (en) * 2004-02-12 2006-11-16 Vander Jagt David L Method and compounds for cancer treatment utilizing NFkB as a direct or ultimate target for small molecule inhibitors
US20070010488A1 (en) 2005-04-13 2007-01-11 Khairia Youssef Compounds for modulating cell proliferation
JP2009521454A (ja) * 2005-12-20 2009-06-04 プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ 化合物、スクリーニング、および処置方法
BRPI0602640B8 (pt) 2006-07-06 2021-05-25 Anhanguera Educacional Ltda métodos de obtenção de penta-1,4-dien-3-onas e de cicloexanonas substituídas e derivados com propriedades antitumorais e antiparasitárias, processo para preparar 1,5-bis-(aril)-penta-1,4-dien-3-onas alquiladas e aciladas, processo para preparar 4-nitro-3,5-diaril-cicloexanonas substituídas, processo para preparar 2,6-dibenzilideno-4-nitro-3,5-diaril-cicloexanonas substituídas, processo para preparar uma mistura formada por quantidades determinadas dos compostos (1,5-bis(4-hidróxi-3-metóxi-fenil)penta-1,4-dien-3-ona) e (1,5-bis(3-metóxi-4-acetóxi-fenil)penta-1,4-dien-3-ona), compostos e seus usos, composição farmacêutica, método terapêutico para tratamento dos cânceres e composição sinérgica

Also Published As

Publication number Publication date
BRPI0902039A8 (pt) 2017-10-03
EP2441452A4 (en) 2013-01-02
BRPI0902039B8 (pt) 2021-05-25
EP2441452A1 (en) 2012-04-18
WO2010142007A1 (pt) 2010-12-16
JP5802658B2 (ja) 2015-10-28
BRPI0902039B1 (pt) 2021-03-30
EP2441452B1 (en) 2018-12-26
JP2012529439A (ja) 2012-11-22
US20120082703A1 (en) 2012-04-05
BRPI0902039A2 (pt) 2011-02-22
US9381169B2 (en) 2016-07-05

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