WO2010142007A1 - Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais - Google Patents

Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais Download PDF

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Publication number
WO2010142007A1
WO2010142007A1 PCT/BR2009/000375 BR2009000375W WO2010142007A1 WO 2010142007 A1 WO2010142007 A1 WO 2010142007A1 BR 2009000375 W BR2009000375 W BR 2009000375W WO 2010142007 A1 WO2010142007 A1 WO 2010142007A1
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
prophylaxis
humans
animals
prevention
Prior art date
Application number
PCT/BR2009/000375
Other languages
English (en)
French (fr)
Other versions
WO2010142007A8 (pt
Inventor
Quincoces suárez JOSÉ AGUSTIN
Maria Durvanei Augusto
Pardi Paulo Celso
Faião Flores FERNANDA
Pereira Santos Reginaldo
Gonçales Rando DANIELA
Original Assignee
Universidade Bandeirante De São Paulo - Academia Paulista Anchieta S/C Ltda
Fundação De Amparo À Pesquisa Do Estado De São Paulo - Fapesp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidade Bandeirante De São Paulo - Academia Paulista Anchieta S/C Ltda, Fundação De Amparo À Pesquisa Do Estado De São Paulo - Fapesp filed Critical Universidade Bandeirante De São Paulo - Academia Paulista Anchieta S/C Ltda
Priority to JP2012514299A priority Critical patent/JP5802658B2/ja
Priority to US13/377,194 priority patent/US9381169B2/en
Priority to EP09845661.9A priority patent/EP2441452B1/en
Publication of WO2010142007A1 publication Critical patent/WO2010142007A1/pt
Publication of WO2010142007A8 publication Critical patent/WO2010142007A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A presente invenção refere-se a composições farmacêuticas que compreendem fenolatos metálicos polifuncionais que apresentam aplicações biológicas como adjuvantes antitumorais, citoprotetores, agentes antimetastáticos e agentes antimutagênicos quando associados a quimioterápicos. A presente invenção refere-se ainda ao uso fenolatos metálicos polifuncionais na preparação de medicamentos para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais.
PCT/BR2009/000375 2009-06-09 2009-11-11 Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais WO2010142007A1 (pt)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2012514299A JP5802658B2 (ja) 2009-06-09 2009-11-11 人および動物の腫瘍性疾患の治療、抑制あるいは予防用医薬組成物、および医薬組成物の使用
US13/377,194 US9381169B2 (en) 2009-06-09 2009-11-11 Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals
EP09845661.9A EP2441452B1 (en) 2009-06-09 2009-11-11 Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0902039A BRPI0902039B8 (pt) 2009-06-09 2009-06-09 composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais
BRPI0902039-0 2009-06-09

Publications (2)

Publication Number Publication Date
WO2010142007A1 true WO2010142007A1 (pt) 2010-12-16
WO2010142007A8 WO2010142007A8 (pt) 2012-01-26

Family

ID=43308327

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2009/000375 WO2010142007A1 (pt) 2009-06-09 2009-11-11 Composição farmacêutica e uso de composição farmacêutica para o tratamento, profilaxia ou prevenção de doenças neoplásicas em humanos e animais

Country Status (5)

Country Link
US (1) US9381169B2 (pt)
EP (1) EP2441452B1 (pt)
JP (1) JP5802658B2 (pt)
BR (1) BRPI0902039B8 (pt)
WO (1) WO2010142007A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115414465A (zh) * 2022-10-17 2022-12-02 苏州明人医药生物科技有限公司 Jwa多肽在制备抗肿瘤药协同增效剂方面的应用

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US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4883666A (en) 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US4968733A (en) 1988-09-01 1990-11-06 Akzo N.V. Process for producing microporous powders and membranes
US4976859A (en) 1988-09-01 1990-12-11 Akzo N.V. Integral asymmetric polyether-sulfone membrane, process for its production, and use for ultrafiltration and microfiltration
US5082670A (en) 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
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US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
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US5284761A (en) 1987-11-17 1994-02-08 Brown University Research Foundation Method of encapsulating cells in a tubular extrudate
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Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4883666A (en) 1987-04-29 1989-11-28 Massachusetts Institute Of Technology Controlled drug delivery system for treatment of neural disorders
US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5284761A (en) 1987-11-17 1994-02-08 Brown University Research Foundation Method of encapsulating cells in a tubular extrudate
US4968733A (en) 1988-09-01 1990-11-06 Akzo N.V. Process for producing microporous powders and membranes
US4976859A (en) 1988-09-01 1990-12-11 Akzo N.V. Integral asymmetric polyether-sulfone membrane, process for its production, and use for ultrafiltration and microfiltration
US5082670A (en) 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5618531A (en) 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord
WO1992019195A1 (en) 1991-04-25 1992-11-12 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
WO1995005452A2 (en) 1993-08-12 1995-02-23 Cytotherapeutics, Inc. Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
WO1996011698A1 (en) 1994-10-14 1996-04-25 Symphony Pharmaceuticals, Inc. Allosteric modulators of the nmda receptor
WO2001040188A1 (en) * 1999-12-03 2001-06-07 Emory University Curcumin analogues for treating cancer
US20060258752A1 (en) * 2004-02-12 2006-11-16 Vander Jagt David L Method and compounds for cancer treatment utilizing NFkB as a direct or ultimate target for small molecule inhibitors
WO2006044379A2 (en) * 2004-10-15 2006-04-27 University Of North Carolina At Chapel Hill Novel curcumin analogues and uses thereof
US20070010488A1 (en) * 2005-04-13 2007-01-11 Khairia Youssef Compounds for modulating cell proliferation
WO2007075772A2 (en) * 2005-12-20 2007-07-05 President And Fellows Of Harvard College Compounds, screens, and methods of treatment
WO2008003155A2 (en) * 2006-07-06 2008-01-10 Uniban - Universidade Bandeirante De São Paulo - Academia Paulista Anchieta S/C Ltda Methods to prepare penta-1,4-dien-3-ones and substituted cyclohexanones and derivatives with antitumoral and antiparasitic properties, the compounds and their uses
BRPI0602640A (pt) 2006-07-06 2008-02-26 Fundacao De Amparo A Pesquisa método de obtenção de penta-1,4-dien-3-onas de cicloexanonas substituìdas e derivados com propriedades antitumorais e antiparasitárias, processo para preparar 1,5-bis-(aril)-penta-1,4-dien-3-onas alquiladas e aciladas, processo para preparar 4-nitro-3,5-diaril-cicloexanonas substituìdas, processo para preparar 2,6-dibenzilideno-4-nitro-3,5-diaril-cicloexanonas substituìdas, processo para preparar uma mistura formada por quantidades determinadas dos compostos (1,5-bis(4-hidróxi-3-metóxi-fenil)penta-1,4-dien-3-ona) e (1,5-bis(3-metóxi-4-acetóxi-fenil)penta-1,4-dien-3-ona), compostos e seus usos, composição farmacêutica, método terapêutico para tratamento dos cánceres e composição sinérgica

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See also references of EP2441452A4
SHUKO, Y., HUMAN AND EXP. TOXICOL., vol. 23, no. 5, 2004, pages 245 - 250
SILVA, S.: "C. Evaluation of possible genotoxic effects of Gergilim", SESAMUM INDICUM L., 2003
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115414465A (zh) * 2022-10-17 2022-12-02 苏州明人医药生物科技有限公司 Jwa多肽在制备抗肿瘤药协同增效剂方面的应用

Also Published As

Publication number Publication date
BRPI0902039A8 (pt) 2017-10-03
BRPI0902039B1 (pt) 2021-03-30
US9381169B2 (en) 2016-07-05
BRPI0902039A2 (pt) 2011-02-22
BRPI0902039B8 (pt) 2021-05-25
US20120082703A1 (en) 2012-04-05
WO2010142007A8 (pt) 2012-01-26
EP2441452B1 (en) 2018-12-26
JP5802658B2 (ja) 2015-10-28
EP2441452A1 (en) 2012-04-18
JP2012529439A (ja) 2012-11-22
EP2441452A4 (en) 2013-01-02

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